LV10053B - Process for preparing a concentrate of blood coagulation factor viii-von willebrand factor complex from total plasma - Google Patents

Process for preparing a concentrate of blood coagulation factor viii-von willebrand factor complex from total plasma Download PDF

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Publication number
LV10053B
LV10053B LVP-92-496A LV920496A LV10053B LV 10053 B LV10053 B LV 10053B LV 920496 A LV920496 A LV 920496A LV 10053 B LV10053 B LV 10053B
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LV
Latvia
Prior art keywords
quot
treatment
concentration
buffer
chromatography
Prior art date
Application number
LVP-92-496A
Other languages
English (en)
Latvian (lv)
Other versions
LV10053A (lv
Inventor
Thierry Burnouf
Miryana Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of LV10053A publication Critical patent/LV10053A/xx
Publication of LV10053B publication Critical patent/LV10053B/lv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
LVP-92-496A 1989-09-05 1992-12-24 Process for preparing a concentrate of blood coagulation factor viii-von willebrand factor complex from total plasma LV10053B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8911567A FR2651437A1 (fr) 1989-09-05 1989-09-05 Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.

Publications (2)

Publication Number Publication Date
LV10053A LV10053A (lv) 1994-05-10
LV10053B true LV10053B (en) 1995-02-20

Family

ID=9385124

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-496A LV10053B (en) 1989-09-05 1992-12-24 Process for preparing a concentrate of blood coagulation factor viii-von willebrand factor complex from total plasma

Country Status (24)

Country Link
US (1) US5679776A (enExample)
EP (1) EP0416983B1 (enExample)
AT (1) ATE91896T1 (enExample)
AU (1) AU627618B2 (enExample)
BR (1) BR9004626A (enExample)
CA (1) CA2024667C (enExample)
CZ (1) CZ277939B6 (enExample)
DD (1) DD298110A5 (enExample)
DE (1) DE69002427T2 (enExample)
DK (1) DK0416983T3 (enExample)
ES (1) ES2057475T3 (enExample)
FI (1) FI95654C (enExample)
FR (1) FR2651437A1 (enExample)
HR (1) HRP920768B1 (enExample)
HU (1) HU206378B (enExample)
LT (1) LT3418B (enExample)
LV (1) LV10053B (enExample)
NO (1) NO178716C (enExample)
PL (1) PL164754B1 (enExample)
RU (1) RU2025129C1 (enExample)
SI (1) SI9012034B (enExample)
SK (1) SK279367B6 (enExample)
UA (1) UA26847C2 (enExample)
YU (1) YU48356B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3904354A1 (de) * 1989-02-14 1990-08-16 Behringwerke Ag Pasteurisiertes, gereinigtes von willebrand-faktor-konzentrat und verfahren zu seiner herstellung
ES2042138T3 (es) * 1989-05-24 1993-12-01 Miles Inc. Filtracion en gel del factor viii tratado termicamente.
AT403991B (de) * 1990-04-04 1998-07-27 Atomic Austria Gmbh Alpinschi
AT403992B (de) * 1991-02-22 1998-07-27 Head Sport Ag Ski
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie
IT1256622B (it) * 1992-12-04 1995-12-12 Sclavo Spa Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii:c-fvw) da plasma umano totale.
DE4430205A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
AT406373B (de) * 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
EP1029546A1 (en) * 1997-11-05 2000-08-23 Yoshitomi Pharmaceutical Industries, Ltd. Heparin cofactor ii preparations and process for producing the same
DE69811628T2 (de) 1998-02-11 2003-12-18 Zlb Bioplasma Ag, Bern Verfahren zur Entfernung von Erregern übertragbarer spongiformer Encephalophatien aus Proteinlösungen
PT2193809E (pt) 1999-02-22 2015-08-24 Baxter Int Formulações de fator viii livres de albumina
DE19937218A1 (de) * 1999-08-06 2001-02-08 Aventis Behring Gmbh Verfahren zur Reindarstellung der den Blutgerinnungsfaktor VII aktivierenden Protease, ihres Proenzyms oder eines Gemisches beider Proteine mittels Affinitätschromatographie
ES2229931B1 (es) * 2003-10-03 2006-01-16 Grifols, S.A. Composicion liquida bilogicamente estable de fviii, de fvw o del complejo fviii/fvw humanos.
RU2253475C1 (ru) * 2004-02-02 2005-06-10 Общество с ограниченной ответственностью "Гемоцентр" Способ получения препарата фактора viii
FR2874216B1 (fr) * 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
BRPI0921429B1 (pt) 2008-11-07 2022-07-12 Takeda Pharmaceutical Company Limited Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável
US20150080309A1 (en) 2012-04-24 2015-03-19 Nova Nordisk A/S Compounds Suitable for Treatment of Haemophilia
ES2693380T3 (es) 2013-11-08 2018-12-11 Csl Limited Nuevo método para concentrar el factor de von Willebrand o complejos de este
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
CN104231073B (zh) * 2014-09-25 2017-01-25 广东双林生物制药有限公司 一种人凝血因子viii的制备方法
CN105315365A (zh) * 2015-11-17 2016-02-10 上海洲跃生物科技有限公司 一种人抗凝血酶iii的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803115A (en) * 1972-05-17 1974-04-09 Baxter Laboratories Inc Stabilization of ahf using heparin
ES471858A1 (es) * 1977-07-25 1979-02-01 Monsanto Co Un metodo para separar el factor especifico de coagulacion de la sangre de una mezcla con otras proteinas de la sangre en un medio fluido
US4386068A (en) * 1980-02-26 1983-05-31 Cutter Laboratories, Inc. Antihemophilic factor concentrate and method for preparation
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
US4435318A (en) * 1981-05-22 1984-03-06 Ionics, Incorporated Electrodialysis preparation of purified AHF concentrate
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4495175A (en) * 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
US4952675A (en) * 1985-02-01 1990-08-28 New York University Method for purifying antihemophilic factor
FR2632309B1 (fr) 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus

Also Published As

Publication number Publication date
YU203490A (sh) 1993-05-28
SI9012034B (sl) 1999-12-31
EP0416983A1 (fr) 1991-03-13
DD298110A5 (de) 1992-02-06
PL286746A1 (en) 1991-05-06
HU905797D0 (en) 1991-03-28
HRP920768A2 (en) 1995-02-28
CA2024667C (en) 2001-07-31
AU627618B2 (en) 1992-08-27
ATE91896T1 (de) 1993-08-15
SK431290A3 (en) 1998-10-07
EP0416983B1 (fr) 1993-07-28
HUT56858A (en) 1991-10-28
FI904381A0 (fi) 1990-09-05
LT3418B (en) 1995-09-25
HRP920768B1 (en) 1998-12-31
ES2057475T3 (es) 1994-10-16
NO903865D0 (no) 1990-09-05
SK279367B6 (sk) 1998-10-07
US5679776A (en) 1997-10-21
FI95654C (fi) 1996-03-11
DE69002427T2 (de) 1993-12-23
AU6221890A (en) 1992-03-12
DE69002427D1 (de) 1993-09-02
DK0416983T3 (da) 1993-10-04
LTIP263A (en) 1994-10-25
FI95654B (fi) 1995-11-30
LV10053A (lv) 1994-05-10
NO903865L (no) 1991-03-06
PL164754B1 (pl) 1994-10-31
CZ431290A3 (en) 1993-01-13
NO178716B (no) 1996-02-12
CA2024667A1 (en) 1991-03-06
FR2651437B1 (enExample) 1994-08-19
FR2651437A1 (fr) 1991-03-08
SI9012034A (en) 1997-10-31
HU206378B (en) 1992-10-28
BR9004626A (pt) 1992-03-24
NO178716C (no) 1996-05-22
UA26847C2 (uk) 1999-12-29
YU48356B (sh) 1998-07-10
CZ277939B6 (en) 1993-06-16
RU2025129C1 (ru) 1994-12-30

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