LU88482A1 - Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules - Google Patents

Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules Download PDF

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Publication number
LU88482A1
LU88482A1 LU88482A LU88482A LU88482A1 LU 88482 A1 LU88482 A1 LU 88482A1 LU 88482 A LU88482 A LU 88482A LU 88482 A LU88482 A LU 88482A LU 88482 A1 LU88482 A1 LU 88482A1
Authority
LU
Luxembourg
Prior art keywords
biocompatible polymer
particles
stirring
support phase
active principle
Prior art date
Application number
LU88482A
Other languages
English (en)
French (fr)
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of LU88482A1 publication Critical patent/LU88482A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
LU88482A 1993-05-15 1994-05-11 Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules LU88482A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (1)

Publication Number Publication Date
LU88482A1 true LU88482A1 (fr) 1994-12-01

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
LU88482A LU88482A1 (fr) 1993-05-15 1994-05-11 Procédé pour la préparation de particules préparées à sec, particules préparées à sec ainsi obtenues et compositions pharmaceutiques contenant de telles particules

Country Status (35)

Country Link
JP (1) JP3139913B2 (nl)
KR (1) KR100341261B1 (nl)
CN (1) CN1050534C (nl)
AT (1) AT406017B (nl)
AU (1) AU685094B2 (nl)
BE (1) BE1008323A3 (nl)
BR (1) BR9401968A (nl)
CA (1) CA2123481C (nl)
CH (1) CH688572A5 (nl)
DE (1) DE4416812C2 (nl)
DK (1) DK171454B1 (nl)
DZ (1) DZ1779A1 (nl)
ES (1) ES2097083B1 (nl)
FI (1) FI112915B (nl)
FR (1) FR2705232B1 (nl)
GB (2) GB9310030D0 (nl)
GR (1) GR1002034B (nl)
HK (1) HK1002831A1 (nl)
HU (1) HU220617B1 (nl)
IE (1) IE940392A1 (nl)
IN (1) IN182330B (nl)
IT (1) IT1269508B (nl)
LU (1) LU88482A1 (nl)
MA (1) MA23194A1 (nl)
NL (1) NL9400795A (nl)
NO (1) NO307403B1 (nl)
NZ (1) NZ260520A (nl)
OA (1) OA09939A (nl)
PL (1) PL175780B1 (nl)
PT (1) PT101518B (nl)
RU (1) RU2125869C1 (nl)
SE (1) SE519004C2 (nl)
SG (1) SG46631A1 (nl)
TN (1) TNSN94046A1 (nl)
ZA (1) ZA943316B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69435055T2 (de) * 1993-01-06 2008-12-04 IPSEN Manufacturing Ireland Ltd., Blanchardstown Bioabbaubare Polyester zur Herstellung ionischer molekularer Konjugate mit bioaktiven Polypeptiden
DK0678018T3 (da) * 1993-01-06 2003-04-28 Kinerton Ltd Ion molekylærkonjugater af bionedbrydelige polyestere og bioaktive polypeptider
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
ES2491866T3 (es) 1999-11-15 2014-09-08 Piramal Healthcare (Canada) Limited Disolución biopolimérica acuosa autogelificante controlada por la temperatura y dependiente del pH
KR100558119B1 (ko) 2000-06-16 2006-03-10 가부시키가이샤 닛폰 쇼쿠바이 가교 중합체, 그것의 제조 방법 및 용도
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (nl) * 1987-10-14 1990-01-15 Debiopharm Sa
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
KR0168849B1 (ko) * 1990-04-12 1999-01-15 요시또시 가즈오 피목 조성물 및 그의 제조방법
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE467815B (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
JPH07507768A (ja) * 1992-03-12 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド Ａｃｔｈ含有マイクロスフェアの制御放出
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
EP0644771B2 (en) * 1992-06-11 2006-12-06 Alkermes Controlled Therapeutics, Inc. Erythropoietin drug delivery system
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
PL175780B1 (pl) 1999-02-26
IT1269508B (it) 1997-04-01
FR2705232A1 (fr) 1994-11-25
IN182330B (nl) 1999-03-20
CN1104557A (zh) 1995-07-05
AU685094B2 (en) 1998-01-15
GB2277915B (en) 1997-10-29
AT406017B (de) 2000-01-25
HU9401412D0 (en) 1994-08-29
ATA98794A (de) 1999-06-15
GR1002034B (en) 1995-10-31
CA2123481A1 (en) 1994-11-16
JPH072652A (ja) 1995-01-06
IE940392A1 (en) 1994-11-16
PT101518B (pt) 2000-12-29
AU6308494A (en) 1994-11-17
KR100341261B1 (ko) 2002-09-27
HU220617B1 (hu) 2002-03-28
DK171454B1 (da) 1996-11-04
DZ1779A1 (fr) 2002-02-17
HUT67599A (en) 1995-04-28
NO941810D0 (no) 1994-05-13
SG46631A1 (en) 1998-02-20
NO941810L (no) 1994-11-16
NZ260520A (en) 1994-12-22
CA2123481C (en) 2005-01-11
FR2705232B1 (fr) 1995-08-25
SE9401557L (sv) 1994-11-16
DE4416812C2 (de) 2003-02-06
GB9310030D0 (en) 1993-06-30
NL9400795A (nl) 1994-12-01
SE9401557D0 (sv) 1994-05-05
ES2097083B1 (es) 1997-12-01
TNSN94046A1 (fr) 1995-04-25
SE519004C2 (sv) 2002-12-17
CN1050534C (zh) 2000-03-22
ZA943316B (en) 1995-01-16
BR9401968A (pt) 1994-12-13
DK54994A (da) 1994-11-16
ITMI940931A1 (it) 1995-11-11
JP3139913B2 (ja) 2001-03-05
FI942222A (fi) 1994-11-16
OA09939A (fr) 1994-11-15
NO307403B1 (no) 2000-04-03
BE1008323A3 (fr) 1996-04-02
GB2277915A (en) 1994-11-16
MA23194A1 (fr) 1994-12-31
HK1002831A1 (en) 1998-09-18
FI942222A0 (fi) 1994-05-13
RU2125869C1 (ru) 1999-02-10
PT101518A (pt) 1995-03-01
DE4416812A1 (de) 1994-11-17
FI112915B (fi) 2004-02-13
CH688572A5 (fr) 1997-11-28
ITMI940931A0 (it) 1994-05-11
ES2097083A1 (es) 1997-03-16
GB9409565D0 (en) 1994-07-06

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