IT1269508B - Procedimento per la preparazione di particelle lavorate a secco, particelle lavorate a secco cosi' ottenute e composizioni farmaceutiche contenenti le particelle - Google Patents

Procedimento per la preparazione di particelle lavorate a secco, particelle lavorate a secco cosi' ottenute e composizioni farmaceutiche contenenti le particelle

Info

Publication number
IT1269508B
IT1269508B ITMI940931A ITMI940931A IT1269508B IT 1269508 B IT1269508 B IT 1269508B IT MI940931 A ITMI940931 A IT MI940931A IT MI940931 A ITMI940931 A IT MI940931A IT 1269508 B IT1269508 B IT 1269508B
Authority
IT
Italy
Prior art keywords
particles
dry
worked
procedure
preparation
Prior art date
Application number
ITMI940931A
Other languages
English (en)
Italian (it)
Inventor
Jean Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ITMI940931A0 publication Critical patent/ITMI940931A0/it
Publication of ITMI940931A1 publication Critical patent/ITMI940931A1/it
Application granted granted Critical
Publication of IT1269508B publication Critical patent/IT1269508B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
ITMI940931A 1993-05-15 1994-05-11 Procedimento per la preparazione di particelle lavorate a secco, particelle lavorate a secco cosi' ottenute e composizioni farmaceutiche contenenti le particelle IT1269508B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (3)

Publication Number Publication Date
ITMI940931A0 ITMI940931A0 (it) 1994-05-11
ITMI940931A1 ITMI940931A1 (it) 1995-11-11
IT1269508B true IT1269508B (it) 1997-04-01

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940931A IT1269508B (it) 1993-05-15 1994-05-11 Procedimento per la preparazione di particelle lavorate a secco, particelle lavorate a secco cosi' ottenute e composizioni farmaceutiche contenenti le particelle

Country Status (35)

Country Link
JP (1) JP3139913B2 (nl)
KR (1) KR100341261B1 (nl)
CN (1) CN1050534C (nl)
AT (1) AT406017B (nl)
AU (1) AU685094B2 (nl)
BE (1) BE1008323A3 (nl)
BR (1) BR9401968A (nl)
CA (1) CA2123481C (nl)
CH (1) CH688572A5 (nl)
DE (1) DE4416812C2 (nl)
DK (1) DK171454B1 (nl)
DZ (1) DZ1779A1 (nl)
ES (1) ES2097083B1 (nl)
FI (1) FI112915B (nl)
FR (1) FR2705232B1 (nl)
GB (2) GB9310030D0 (nl)
GR (1) GR1002034B (nl)
HK (1) HK1002831A1 (nl)
HU (1) HU220617B1 (nl)
IE (1) IE940392A1 (nl)
IN (1) IN182330B (nl)
IT (1) IT1269508B (nl)
LU (1) LU88482A1 (nl)
MA (1) MA23194A1 (nl)
NL (1) NL9400795A (nl)
NO (1) NO307403B1 (nl)
NZ (1) NZ260520A (nl)
OA (1) OA09939A (nl)
PL (1) PL175780B1 (nl)
PT (1) PT101518B (nl)
RU (1) RU2125869C1 (nl)
SE (1) SE519004C2 (nl)
SG (1) SG46631A1 (nl)
TN (1) TNSN94046A1 (nl)
ZA (1) ZA943316B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69435055T2 (de) * 1993-01-06 2008-12-04 IPSEN Manufacturing Ireland Ltd., Blanchardstown Bioabbaubare Polyester zur Herstellung ionischer molekularer Konjugate mit bioaktiven Polypeptiden
PT678018E (pt) * 1993-01-06 2003-08-29 Kinerton Ltd Conjugados moleculares ionicos de poliesteres biodegradaveis e de polipeptidos bioactivos
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
ES2491866T3 (es) 1999-11-15 2014-09-08 Piramal Healthcare (Canada) Limited Disolución biopolimérica acuosa autogelificante controlada por la temperatura y dependiente del pH
GB2374072B (en) * 2000-06-16 2004-09-22 Nippon Catalytic Chem Ind Crosslinked polymer method for manufacturing it and use thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (nl) * 1987-10-14 1990-01-15 Debiopharm Sa
AU2810189A (en) * 1987-10-30 1989-05-23 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
ES2096624T3 (es) * 1990-04-12 1997-03-16 Shionogi & Co Composicion revestida y su procedimiento de preparacion.
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE467815B (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
ATE154240T1 (de) * 1992-03-12 1997-06-15 Alkermes Inc Acth enthaltende mikrokugeln mit gesteuerter abgabe
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
DK0644771T4 (da) * 1992-06-11 2006-12-27 Alkermes Inc Lægemiddelsystem til levering af erythropoietin
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
RU2125869C1 (ru) 1999-02-10
ES2097083A1 (es) 1997-03-16
ATA98794A (de) 1999-06-15
BE1008323A3 (fr) 1996-04-02
DK171454B1 (da) 1996-11-04
SE519004C2 (sv) 2002-12-17
KR100341261B1 (ko) 2002-09-27
CA2123481C (en) 2005-01-11
CH688572A5 (fr) 1997-11-28
LU88482A1 (fr) 1994-12-01
DK54994A (da) 1994-11-16
ES2097083B1 (es) 1997-12-01
JPH072652A (ja) 1995-01-06
CA2123481A1 (en) 1994-11-16
OA09939A (fr) 1994-11-15
GR1002034B (en) 1995-10-31
AU6308494A (en) 1994-11-17
GB9409565D0 (en) 1994-07-06
FI942222A0 (fi) 1994-05-13
CN1104557A (zh) 1995-07-05
FI942222A (fi) 1994-11-16
DE4416812C2 (de) 2003-02-06
ZA943316B (en) 1995-01-16
AU685094B2 (en) 1998-01-15
GB2277915A (en) 1994-11-16
DE4416812A1 (de) 1994-11-17
NO307403B1 (no) 2000-04-03
PT101518B (pt) 2000-12-29
HU9401412D0 (en) 1994-08-29
FR2705232B1 (fr) 1995-08-25
SE9401557L (sv) 1994-11-16
HK1002831A1 (en) 1998-09-18
CN1050534C (zh) 2000-03-22
IE940392A1 (en) 1994-11-16
SG46631A1 (en) 1998-02-20
DZ1779A1 (fr) 2002-02-17
HU220617B1 (hu) 2002-03-28
SE9401557D0 (sv) 1994-05-05
NZ260520A (en) 1994-12-22
ITMI940931A0 (it) 1994-05-11
HUT67599A (en) 1995-04-28
TNSN94046A1 (fr) 1995-04-25
FI112915B (fi) 2004-02-13
AT406017B (de) 2000-01-25
NL9400795A (nl) 1994-12-01
BR9401968A (pt) 1994-12-13
GB9310030D0 (en) 1993-06-30
ITMI940931A1 (it) 1995-11-11
PT101518A (pt) 1995-03-01
GB2277915B (en) 1997-10-29
FR2705232A1 (fr) 1994-11-25
IN182330B (nl) 1999-03-20
NO941810D0 (no) 1994-05-13
NO941810L (no) 1994-11-16
MA23194A1 (fr) 1994-12-31
JP3139913B2 (ja) 2001-03-05
PL175780B1 (pl) 1999-02-26

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529