LU86747A1 - Nouveaux derives de dihydrobenzofuranne-et de chromane-carboxamides,leurs procedes de preparation et leur utilisation comme neuroleptiques - Google Patents

Nouveaux derives de dihydrobenzofuranne-et de chromane-carboxamides,leurs procedes de preparation et leur utilisation comme neuroleptiques Download PDF

Info

Publication number
LU86747A1
LU86747A1 LU86747A LU86747A LU86747A1 LU 86747 A1 LU86747 A1 LU 86747A1 LU 86747 A LU86747 A LU 86747A LU 86747 A LU86747 A LU 86747A LU 86747 A1 LU86747 A1 LU 86747A1
Authority
LU
Luxembourg
Prior art keywords
methyl
formula
water
group
carboxamide
Prior art date
Application number
LU86747A
Other languages
English (en)
French (fr)
Inventor
Jacqueline Franceschini
Josette Margarit
Original Assignee
Delagrange Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delagrange Lab filed Critical Delagrange Lab
Publication of LU86747A1 publication Critical patent/LU86747A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
LU86747A 1986-01-30 1987-01-28 Nouveaux derives de dihydrobenzofuranne-et de chromane-carboxamides,leurs procedes de preparation et leur utilisation comme neuroleptiques LU86747A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8601279A FR2593504B1 (fr) 1986-01-30 1986-01-30 Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
FR8601279 1986-01-30

Publications (1)

Publication Number Publication Date
LU86747A1 true LU86747A1 (fr) 1987-06-02

Family

ID=9331629

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86747A LU86747A1 (fr) 1986-01-30 1987-01-28 Nouveaux derives de dihydrobenzofuranne-et de chromane-carboxamides,leurs procedes de preparation et leur utilisation comme neuroleptiques

Country Status (40)

Country Link
US (1) US5006570A (cs)
EP (1) EP0231139B1 (cs)
JP (1) JPS62277376A (cs)
KR (1) KR870007160A (cs)
CN (2) CN1016420B (cs)
AT (1) ATE70063T1 (cs)
AU (1) AU593605B2 (cs)
BE (1) BE1000164A5 (cs)
BG (1) BG46600A3 (cs)
CA (1) CA1300161C (cs)
CH (1) CH670827A5 (cs)
CS (2) CS264288B2 (cs)
DD (1) DD260065A5 (cs)
DE (2) DE3702005A1 (cs)
DK (1) DK46987A (cs)
ES (2) ES2038679T3 (cs)
FI (1) FI870347A (cs)
FR (1) FR2593504B1 (cs)
GB (1) GB2187188B (cs)
GR (2) GR870134B (cs)
HU (1) HU206107B (cs)
IE (1) IE870128L (cs)
IL (1) IL81299A (cs)
IN (2) IN164389B (cs)
IS (1) IS1446B6 (cs)
IT (1) IT1205729B (cs)
LU (1) LU86747A1 (cs)
MA (1) MA20861A1 (cs)
NO (1) NO168582C (cs)
NZ (1) NZ219068A (cs)
OA (1) OA08472A (cs)
PH (1) PH23392A (cs)
PL (2) PL152404B1 (cs)
PT (1) PT84224B (cs)
SU (2) SU1609451A3 (cs)
TN (1) TNSN87012A1 (cs)
YU (1) YU46185B (cs)
ZA (1) ZA87552B (cs)
ZM (1) ZM987A1 (cs)
ZW (1) ZW1387A1 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611713B1 (fr) * 1987-02-27 1990-11-30 Adir Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2611715B1 (fr) * 1987-02-27 1989-05-12 Adir Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
JP2726306B2 (ja) * 1989-04-14 1998-03-11 本田技研工業株式会社 車両の前後輪操舵装置
US5122361A (en) * 1989-04-17 1992-06-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and imaging agents
EP0412939A3 (en) * 1989-08-11 1991-09-04 Ciba-Geigy Ag Certain benzopyran and benzothiopyran derivatives
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
GB9005014D0 (en) 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
WO1991017144A1 (en) * 1990-05-02 1991-11-14 Yoshitomi Pharmaceutical Industries, Ltd. Amide compound, pharmaceutical use thereof and novel 1-substituted pyrrolidinemethyl-amines
US5114947A (en) * 1990-12-27 1992-05-19 Erbamont Inc. Method for alleviating anxiety using benzobicyclic carboxamides
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
CA2129112A1 (en) * 1992-02-06 1993-08-19 Francis David King Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists
US5708174A (en) * 1992-03-12 1998-01-13 Smithkline Beecham P.L.C. Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists
US6127379A (en) * 1993-02-01 2000-10-03 Smithkline Beecham P.L.C. Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途
JPH0820586A (ja) * 1994-07-05 1996-01-23 Sanwa Kagaku Kenkyusho Co Ltd １−アザビシクロ［３．３．０］オクタン誘導体、その塩及び製法並びに用途
JPH0873463A (ja) * 1994-07-05 1996-03-19 Sanwa Kagaku Kenkyusho Co Ltd ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135545A1 (en) * 1983-02-19 1985-04-03 Beecham Group Plc Azabicycloalkyl benzamide and anilide derivatives
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体

Also Published As

Publication number Publication date
PL152491B1 (en) 1990-12-31
KR870007160A (ko) 1987-08-17
CN1062144A (zh) 1992-06-24
IS3189A7 (is) 1987-07-31
US5006570A (en) 1991-04-09
CH670827A5 (cs) 1989-07-14
CN87100978A (zh) 1987-09-16
YU11387A (en) 1988-06-30
CS36288A2 (en) 1988-09-16
AU593605B2 (en) 1990-02-15
NZ219068A (en) 1990-12-21
NO168582C (no) 1992-03-11
DD260065A5 (de) 1988-09-14
GR870134B (en) 1987-05-28
IE870128L (en) 1987-07-30
ES2038679T3 (es) 1993-08-01
HU206107B (en) 1992-08-28
ZM987A1 (en) 1987-09-30
ES2003671A6 (es) 1988-11-01
FR2593504A1 (fr) 1987-07-31
ZW1387A1 (en) 1987-10-28
IS1446B6 (is) 1990-12-14
FR2593504B1 (fr) 1988-12-09
PL263885A1 (en) 1988-09-15
IT1205729B (it) 1989-03-31
CN1016420B (zh) 1992-04-29
PL272298A1 (en) 1989-02-20
AU6785587A (en) 1987-08-06
IN164389B (cs) 1989-03-04
OA08472A (fr) 1988-07-29
PL152404B1 (en) 1990-12-31
ATE70063T1 (de) 1991-12-15
NO168582B (no) 1991-12-02
DK46987A (da) 1987-07-31
EP0231139B1 (fr) 1991-12-04
HUT47093A (en) 1989-01-30
PT84224B (pt) 1989-03-30
CA1300161C (fr) 1992-05-05
EP0231139A3 (en) 1988-04-27
BG46600A3 (en) 1990-01-15
GB2187188A (en) 1987-09-03
TNSN87012A1 (fr) 1990-01-01
PT84224A (fr) 1987-02-01
DE3774888D1 (de) 1992-01-16
YU46185B (sh) 1993-05-28
IL81299A (en) 1991-09-16
IT8747583A0 (it) 1987-01-29
IN167060B (cs) 1990-08-25
GB8701870D0 (en) 1987-03-04
IL81299A0 (en) 1987-08-31
DE3702005A1 (de) 1987-08-06
MA20861A1 (fr) 1987-10-01
CS264288B2 (en) 1989-06-13
SU1609451A3 (ru) 1990-11-23
FI870347A0 (fi) 1987-01-27
CS264300B2 (cs) 1989-06-13
FI870347A (fi) 1987-07-31
JPS62277376A (ja) 1987-12-02
DK46987D0 (da) 1987-01-29
GB2187188B (en) 1989-11-08
GR3003653T3 (cs) 1993-03-16
PH23392A (en) 1989-07-26
ZA87552B (en) 1987-10-28
BE1000164A5 (fr) 1988-07-05
NO870199L (no) 1987-07-31
NO870199D0 (no) 1987-01-16
EP0231139A2 (fr) 1987-08-05
SU1607688A3 (ru) 1990-11-15
CS57887A2 (en) 1988-09-16

Similar Documents

Publication Publication Date Title
LU86747A1 (fr) Nouveaux derives de dihydrobenzofuranne-et de chromane-carboxamides,leurs procedes de preparation et leur utilisation comme neuroleptiques
CA2057578C (fr) Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
FR2567885A1 (fr) Derives 3-aminopropoxyaryliques, leur preparation, leur application comme medicaments et compositions pharmaceutiques les contenant
EP0210084A1 (fr) Amides, procédés pour leur préparation et médicaments les contenant
EP0449699A2 (fr) Dérivés de pyrazole antagonistes des récepteurs à l'angiotensine II, leurs procédés de préparation, compositions pharmaceutiques les contenant
FR2581993A1 (fr) Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
BE1003848A3 (fr) Nouveaux derives de la thiouree, leur preparation et leur utilisation comme medicaments.
FR2584713A1 (fr) Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
EP1885695B8 (fr) Composes de l'indoline
FR2534582A1 (fr) Nouveaux derives de benzofuranne et de benzothiophene, utiles comme agents anti-hyperuricemie et anti-hypertension, et leur procede de fabrication
EP0858459B1 (fr) Nouveaux derives de pyrazoles acides, leur procede de preparation, leur application a titre de medicaments, leur nouvelle utilisation et les compositions pharmaceutiques les renfermant
CA2015669A1 (fr) Derives du 4-phenylmethyl 1h-indole, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
EP0891358A1 (fr) Composes derives d'oxazolidin-2-one, leur procede de preparation et leur application en therapeutique
FR2512443A1 (fr) Derives de phenoxy-3 propanol-2, leur preparation et leur application en therapeutique
EP0382628B1 (fr) Dérivés aminoalkoxyphényle, leur procédé de préparation ainsi que les compositions en contenant
EP0282390B1 (fr) Nouveaux dérivés de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acétique et les compositions pharmaceutiques qui les contiennent
EP0728755B1 (fr) Nouveaux composés du thiophène, leur procédé de préparation et les compositions pharmaceutiques les renfermant
CH624389A5 (en) Process for the preparation of new methylamine derivatives
EP0233801B1 (fr) Nouveaux amides substitués, leur préparation et les compositions pharmaceutiques qui les contiennent
EP2185511A2 (fr) Dérivés de 1-oxo-isoindoline-4-carboxamides et de 1-oxo-1,2,3,4-tetrahydroisoquinoleine-5-carboxamides, leur préparation et leur application en thérapeutique
CA1313872C (fr) Acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
CH667873A5 (fr) Derive de n-imidazolidinylmethyl benzamide.
FR2551753A2 (fr) Benzotriazine-1,2,3-ones-4, procede de preparation et medicaments les contenant
EP0288647B1 (fr) Dérivés du [(pyrrolidinyl-1)-2éthoxy]-5 p-cymène, le procédé de préparation desdits dérivés et les médicaments contenant lesdits dérivés
EP0057337A1 (fr) Dérivés du 4H-benzo(4,5)cyclohepta(1,2-b)furanne, leur procédé de préparation et leur application en tant que médicaments