IL81299A - N-(2-pyrrolidinylmethyl)-dihydrobenzofuran-and chroman-carboxamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
N-(2-pyrrolidinylmethyl)-dihydrobenzofuran-and chroman-carboxamide derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL81299A IL81299A IL81299A IL8129987A IL81299A IL 81299 A IL81299 A IL 81299A IL 81299 A IL81299 A IL 81299A IL 8129987 A IL8129987 A IL 8129987A IL 81299 A IL81299 A IL 81299A
- Authority
- IL
- Israel
- Prior art keywords
- dihydrobenzofuran
- chroman
- preparation
- carboxamide derivatives
- pyrrolidinylmethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polyamides (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8601279A FR2593504B1 (fr) | 1986-01-30 | 1986-01-30 | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL81299A0 IL81299A0 (en) | 1987-08-31 |
| IL81299A true IL81299A (en) | 1991-09-16 |
Family
ID=9331629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81299A IL81299A (en) | 1986-01-30 | 1987-01-19 | N-(2-pyrrolidinylmethyl)-dihydrobenzofuran-and chroman-carboxamide derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US5006570A (cs) |
| EP (1) | EP0231139B1 (cs) |
| JP (1) | JPS62277376A (cs) |
| KR (1) | KR870007160A (cs) |
| CN (2) | CN1016420B (cs) |
| AT (1) | ATE70063T1 (cs) |
| AU (1) | AU593605B2 (cs) |
| BE (1) | BE1000164A5 (cs) |
| BG (1) | BG46600A3 (cs) |
| CA (1) | CA1300161C (cs) |
| CH (1) | CH670827A5 (cs) |
| CS (2) | CS264288B2 (cs) |
| DD (1) | DD260065A5 (cs) |
| DE (2) | DE3702005A1 (cs) |
| DK (1) | DK46987A (cs) |
| ES (2) | ES2038679T3 (cs) |
| FI (1) | FI870347A (cs) |
| FR (1) | FR2593504B1 (cs) |
| GB (1) | GB2187188B (cs) |
| GR (2) | GR870134B (cs) |
| HU (1) | HU206107B (cs) |
| IE (1) | IE870128L (cs) |
| IL (1) | IL81299A (cs) |
| IN (2) | IN164389B (cs) |
| IS (1) | IS1446B6 (cs) |
| IT (1) | IT1205729B (cs) |
| LU (1) | LU86747A1 (cs) |
| MA (1) | MA20861A1 (cs) |
| NO (1) | NO168582C (cs) |
| NZ (1) | NZ219068A (cs) |
| OA (1) | OA08472A (cs) |
| PH (1) | PH23392A (cs) |
| PL (2) | PL152404B1 (cs) |
| PT (1) | PT84224B (cs) |
| SU (2) | SU1609451A3 (cs) |
| TN (1) | TNSN87012A1 (cs) |
| YU (1) | YU46185B (cs) |
| ZA (1) | ZA87552B (cs) |
| ZM (1) | ZM987A1 (cs) |
| ZW (1) | ZW1387A1 (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2611713B1 (fr) * | 1987-02-27 | 1990-11-30 | Adir | Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2611715B1 (fr) * | 1987-02-27 | 1989-05-12 | Adir | Nouveaux acetamides derives de la dihydro-2,3 phenyl-3 benzofurannone-2, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
| JP2726306B2 (ja) * | 1989-04-14 | 1998-03-11 | 本田技研工業株式会社 | 車両の前後輪操舵装置 |
| US5122361A (en) * | 1989-04-17 | 1992-06-16 | Trustees Of The University Of Pennsylvania | Dopamine receptor ligands and imaging agents |
| EP0412939A3 (en) * | 1989-08-11 | 1991-09-04 | Ciba-Geigy Ag | Certain benzopyran and benzothiopyran derivatives |
| US5420151A (en) * | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| US5616610A (en) * | 1989-12-22 | 1997-04-01 | Astra Aktiebolag | (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans |
| GB9005014D0 (en) | 1990-03-06 | 1990-05-02 | Janssen Pharmaceutica Nv | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
| WO1991017144A1 (en) * | 1990-05-02 | 1991-11-14 | Yoshitomi Pharmaceutical Industries, Ltd. | Amide compound, pharmaceutical use thereof and novel 1-substituted pyrrolidinemethyl-amines |
| US5114947A (en) * | 1990-12-27 | 1992-05-19 | Erbamont Inc. | Method for alleviating anxiety using benzobicyclic carboxamides |
| MA22647A1 (fr) * | 1991-09-14 | 1993-04-01 | Smithkline Beecham Plc | Procede de preparation d'un ester ou d'un amide d'un nouveau produit . |
| CA2129112A1 (en) * | 1992-02-06 | 1993-08-19 | Francis David King | Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists |
| US5708174A (en) * | 1992-03-12 | 1998-01-13 | Smithkline Beecham P.L.C. | Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists |
| US6127379A (en) * | 1993-02-01 | 2000-10-03 | Smithkline Beecham P.L.C. | Benzopyran, benzothiopyran and benzofuran derivatives as 5-HT4 antagonists |
| JP2999669B2 (ja) * | 1993-08-24 | 2000-01-17 | 株式会社三和化学研究所 | ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途 |
| JPH0820586A (ja) * | 1994-07-05 | 1996-01-23 | Sanwa Kagaku Kenkyusho Co Ltd | １−アザビシクロ［３．３．０］オクタン誘導体、その塩及び製法並びに用途 |
| JPH0873463A (ja) * | 1994-07-05 | 1996-03-19 | Sanwa Kagaku Kenkyusho Co Ltd | ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0135545A1 (en) * | 1983-02-19 | 1985-04-03 | Beecham Group Plc | Azabicycloalkyl benzamide and anilide derivatives |
| JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
| CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
| JPS63139180A (ja) * | 1986-12-02 | 1988-06-10 | Tanabe Seiyaku Co Ltd | カルボン酸誘導体 |
-
1986
- 1986-01-30 FR FR8601279A patent/FR2593504B1/fr not_active Expired
-
1987
- 1987-01-16 NO NO870199A patent/NO168582C/no unknown
- 1987-01-19 IL IL81299A patent/IL81299A/xx not_active IP Right Cessation
- 1987-01-20 IE IE870128A patent/IE870128L/xx unknown
- 1987-01-21 IS IS3189A patent/IS1446B6/is unknown
- 1987-01-21 IN IN43/MAS/87A patent/IN164389B/en unknown
- 1987-01-21 AU AU67855/87A patent/AU593605B2/en not_active Ceased
- 1987-01-23 DE DE19873702005 patent/DE3702005A1/de not_active Withdrawn
- 1987-01-23 ZW ZW13/87A patent/ZW1387A1/xx unknown
- 1987-01-26 ZA ZA87552A patent/ZA87552B/xx unknown
- 1987-01-27 YU YU11387A patent/YU46185B/sh unknown
- 1987-01-27 FI FI870347A patent/FI870347A/fi not_active Application Discontinuation
- 1987-01-27 NZ NZ219068A patent/NZ219068A/en unknown
- 1987-01-27 MA MA21095A patent/MA20861A1/fr unknown
- 1987-01-27 GR GR870134A patent/GR870134B/el unknown
- 1987-01-28 LU LU86747A patent/LU86747A1/fr unknown
- 1987-01-28 CA CA000528418A patent/CA1300161C/fr not_active Expired - Lifetime
- 1987-01-28 TN TNTNSN87012A patent/TNSN87012A1/fr unknown
- 1987-01-28 GB GB8701870A patent/GB2187188B/en not_active Expired
- 1987-01-28 BG BG78228A patent/BG46600A3/xx active Active
- 1987-01-28 CN CN87100978A patent/CN1016420B/zh not_active Expired
- 1987-01-28 KR KR870000673A patent/KR870007160A/ko not_active Application Discontinuation
- 1987-01-29 HU HU87283A patent/HU206107B/hu not_active IP Right Cessation
- 1987-01-29 ZM ZM9/87A patent/ZM987A1/xx unknown
- 1987-01-29 IT IT47583/87A patent/IT1205729B/it active
- 1987-01-29 PH PH34786A patent/PH23392A/en unknown
- 1987-01-29 EP EP87400194A patent/EP0231139B1/fr not_active Expired - Lifetime
- 1987-01-29 SU SU874028919A patent/SU1609451A3/ru active
- 1987-01-29 CH CH300/87A patent/CH670827A5/fr not_active IP Right Cessation
- 1987-01-29 DD DD87299591A patent/DD260065A5/de unknown
- 1987-01-29 ES ES198787400194T patent/ES2038679T3/es not_active Expired - Lifetime
- 1987-01-29 PT PT84224A patent/PT84224B/pt not_active IP Right Cessation
- 1987-01-29 DE DE8787400194T patent/DE3774888D1/de not_active Expired - Lifetime
- 1987-01-29 DK DK046987A patent/DK46987A/da unknown
- 1987-01-29 OA OA59056A patent/OA08472A/xx unknown
- 1987-01-29 AT AT87400194T patent/ATE70063T1/de not_active IP Right Cessation
- 1987-01-29 CS CS87578A patent/CS264288B2/cs unknown
- 1987-01-29 ES ES8700216A patent/ES2003671A6/es not_active Expired
- 1987-01-30 PL PL1987263885A patent/PL152404B1/pl unknown
- 1987-01-30 PL PL1987272298A patent/PL152491B1/pl unknown
- 1987-01-30 BE BE8700065A patent/BE1000164A5/fr not_active Expired
- 1987-01-30 JP JP62021649A patent/JPS62277376A/ja active Pending
- 1987-01-30 US US07/008,916 patent/US5006570A/en not_active Expired - Fee Related
-
1988
- 1988-01-19 CS CS88362A patent/CS264300B2/cs unknown
- 1988-05-23 IN IN343/MAS/88A patent/IN167060B/en unknown
- 1988-06-28 SU SU884355973A patent/SU1607688A3/ru active
-
1992
- 1992-01-04 CN CN92100139A patent/CN1062144A/zh active Pending
- 1992-01-27 GR GR920400082T patent/GR3003653T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |