LT4602B - 2-fenil-1,2-benzizoselenazol-3(2h)-ono panaudojimas alchaimerio ligos gydymui skirtai farmacinei kompozicijai gauti - Google Patents

2-fenil-1,2-benzizoselenazol-3(2h)-ono panaudojimas alchaimerio ligos gydymui skirtai farmacinei kompozicijai gauti Download PDF

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Publication number
LT4602B
LT4602B LT99-016A LT99016A LT4602B LT 4602 B LT4602 B LT 4602B LT 99016 A LT99016 A LT 99016A LT 4602 B LT4602 B LT 4602B
Authority
LT
Lithuania
Prior art keywords
compound
alzheimer
treatment
disease
phenyl
Prior art date
Application number
LT99-016A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT99016A (en
Inventor
Ikuro Maruyama
Kazuhiro Abeyama
Hiroyuki Masayasu
Original Assignee
A. Nattermann & Cie. Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A. Nattermann & Cie. Gmbh filed Critical A. Nattermann & Cie. Gmbh
Publication of LT99016A publication Critical patent/LT99016A/xx
Publication of LT4602B publication Critical patent/LT4602B/lt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
LT99-016A 1996-08-27 1999-02-23 2-fenil-1,2-benzizoselenazol-3(2h)-ono panaudojimas alchaimerio ligos gydymui skirtai farmacinei kompozicijai gauti LT4602B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22551296 1996-08-27

Publications (2)

Publication Number Publication Date
LT99016A LT99016A (en) 1999-10-25
LT4602B true LT4602B (lt) 2000-01-25

Family

ID=16830487

Family Applications (1)

Application Number Title Priority Date Filing Date
LT99-016A LT4602B (lt) 1996-08-27 1999-02-23 2-fenil-1,2-benzizoselenazol-3(2h)-ono panaudojimas alchaimerio ligos gydymui skirtai farmacinei kompozicijai gauti

Country Status (29)

Country Link
US (1) US5948800A (fi)
EP (1) EP0826370B1 (fi)
KR (1) KR20000035859A (fi)
CN (1) CN1112922C (fi)
AT (1) ATE219361T1 (fi)
AU (2) AU3866997A (fi)
BR (1) BR9711259A (fi)
CA (1) CA2213794C (fi)
CZ (1) CZ295364B6 (fi)
DE (2) DE59707550D1 (fi)
DK (1) DK0826370T3 (fi)
EE (1) EE03953B1 (fi)
ES (1) ES2177849T3 (fi)
FI (1) FI119622B (fi)
HK (1) HK1020317A1 (fi)
HU (1) HU225264B1 (fi)
IL (1) IL127113A (fi)
LT (1) LT4602B (fi)
LV (1) LV12251B (fi)
NO (1) NO312812B1 (fi)
NZ (1) NZ332292A (fi)
PL (1) PL188481B1 (fi)
PT (1) PT826370E (fi)
SI (1) SI9720060B (fi)
TR (1) TR199700858A2 (fi)
TW (1) TW501925B (fi)
UA (1) UA59367C2 (fi)
WO (2) WO1998008511A1 (fi)
ZA (1) ZA977644B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0729756T3 (da) * 1993-10-27 2000-06-05 Daiichi Seiyaku Co Granulært farmaceutisk præparat
JP2000016935A (ja) * 1998-07-01 2000-01-18 Dai Ichi Seiyaku Co Ltd シクロオキシゲナーゼ阻害剤
CA2368484A1 (en) 1999-03-31 2000-10-05 Daiichi Pharmaceutical Co., Ltd. Substrates for thioredoxin reductase
WO2003010154A1 (en) * 2001-07-26 2003-02-06 Samsung Electronics Co. Ltd. Seleno compounds containing nitrone moiety, their preparation and their therapeutic uses
WO2003010143A1 (en) 2001-07-26 2003-02-06 Samsung Electronics Co., Ltd. Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses
WO2003010153A1 (en) 2001-07-26 2003-02-06 Samsung Electronics Co. Ltd. N-alkyl-n-phenylhydroxylamine compounds containing metal chelating groups, their preparation and their therapeutic uses
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder
CN103965188A (zh) * 2013-01-29 2014-08-06 中山大学 含硒多奈哌齐类似物
EP2950102A1 (en) 2014-05-30 2015-12-02 Biocross, S.L. Method for the diagnosis of alzheimer s disease and mild cognitive impairment
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
EP3067699A1 (en) 2015-03-11 2016-09-14 Neuron Bio, S.A. Method for diagnosing alzheimer's disease
PL237739B1 (pl) 2018-06-06 2021-05-17 Univ Gdanski Genisteina do zastosowania do leczenia choroby Alzheimera
CN113116888B (zh) * 2021-04-19 2022-08-26 上海兴糖生物技术有限公司 依布硒啉的用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0238591A (ja) 1988-07-27 1990-02-07 Fujikura Ltd 高純度銅の製造方法
WO1992002221A1 (en) 1990-08-06 1992-02-20 Rhone-Poulenc Rorer Gmbh Use of 2-phenyl-1,2-benzisoselenazol-3(2h)-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3616923A1 (de) * 1986-05-20 1987-11-26 Nattermann A & Cie Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on
DE3638124C2 (de) * 1986-11-08 1996-09-05 Nattermann A & Cie Neue pharmazeutische Verwendung von Ebselen
JPH01131113A (ja) * 1987-08-27 1989-05-24 Dai Ichi Seiyaku Co Ltd 脳障害治療剤
US5385726A (en) * 1990-08-06 1995-01-31 Rhone-Poulenc Rorer Gmbh Use of 2-phenyl-1,2-benzisoselenazol-3-(2H)-one
FR2669633B1 (fr) * 1990-11-23 1993-01-22 Adir Nouveaux derives de la benzoselenazolinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JPH07233056A (ja) * 1993-09-03 1995-09-05 Dai Ichi Seiyaku Co Ltd リポキシゲナーゼ阻害剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0238591A (ja) 1988-07-27 1990-02-07 Fujikura Ltd 高純度銅の製造方法
WO1992002221A1 (en) 1990-08-06 1992-02-20 Rhone-Poulenc Rorer Gmbh Use of 2-phenyl-1,2-benzisoselenazol-3(2h)-one

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
D.A. DAWSON ET AL.: "The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat", NEUROSCIENCE LETTERS, 1995, pages 65 - 69, XP002040434, DOI: doi:10.1016/0304-3940(94)11226-9
MÜLLER A, ET AL.: "A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen).", BIOCHEM PHARMACOL., 1984, pages 3235 - 3239, XP000654591, DOI: doi:10.1016/0006-2952(84)90083-2
STOHS SJ.: "The role of free radicals in toxicity and disease", J BASIC CLIN PHYSIOL PHARMACOL., 1995, pages 205 - 228, XP002040436

Also Published As

Publication number Publication date
HK1020317A1 (en) 2000-04-14
UA59367C2 (uk) 2003-09-15
CN1112922C (zh) 2003-07-02
HUP9903213A3 (en) 2000-12-28
AU3529897A (en) 1998-03-05
FI982689A0 (fi) 1998-12-11
NO973912L (no) 1998-03-02
SI9720060B (en) 2001-12-31
ZA977644B (en) 1999-02-26
TW501925B (en) 2002-09-11
LV12251B (lv) 1999-08-20
HUP9903213A1 (en) 2000-07-28
KR20000035859A (ko) 2000-06-26
FI982689A (fi) 1998-12-11
PT826370E (pt) 2002-10-31
EE9900007A (et) 1999-06-15
ATE219361T1 (de) 2002-07-15
PL321796A1 (en) 1998-03-02
BR9711259A (pt) 1999-08-17
US5948800A (en) 1999-09-07
HU225264B1 (en) 2006-08-28
CZ295364B6 (cs) 2005-07-13
TR199700858A2 (xx) 1998-03-21
PL188481B1 (pl) 2005-02-28
NO973912D0 (no) 1997-08-26
DE59707550D1 (de) 2002-07-25
SI9720060A (sl) 1999-06-30
FI119622B (fi) 2009-01-30
AU3866997A (en) 1998-03-19
IL127113A0 (en) 1999-09-22
CZ31799A3 (cs) 1999-11-17
WO1998008831A1 (fr) 1998-03-05
IL127113A (en) 2003-07-06
AU725534B2 (en) 2000-10-12
EP0826370A1 (de) 1998-03-04
CA2213794A1 (en) 1998-02-27
EP0826370B1 (de) 2002-06-19
CA2213794C (en) 2006-10-03
NZ332292A (en) 2001-07-27
CN1223580A (zh) 1999-07-21
WO1998008511A1 (de) 1998-03-05
ES2177849T3 (es) 2002-12-16
LT99016A (en) 1999-10-25
LV12251A (lv) 1999-04-20
DE19733690A1 (de) 1998-03-26
DK0826370T3 (da) 2002-10-07
NO312812B1 (no) 2002-07-08
EE03953B1 (et) 2003-02-17

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Effective date: 20050407