LT2807165T - Pirimido[4,5-b]indolo dariniai ir jų panaudojimas kraujodaros kamieninių ląstelių dauginime - Google Patents

Pirimido[4,5-b]indolo dariniai ir jų panaudojimas kraujodaros kamieninių ląstelių dauginime

Info

Publication number
LT2807165T
LT2807165T LTEP13740815.9T LT13740815T LT2807165T LT 2807165 T LT2807165 T LT 2807165T LT 13740815 T LT13740815 T LT 13740815T LT 2807165 T LT2807165 T LT 2807165T
Authority
LT
Lithuania
Prior art keywords
haircle
pyrimide
reproduction
indole derivatives
indole
Prior art date
Application number
LTEP13740815.9T
Other languages
English (en)
Lithuanian (lt)
Inventor
Guy Sauvageau
Yves Gareau
Réjean RUEL
Stéphane GINGRAS
Iman FARES
Original Assignee
Université de Montréal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48872865&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2807165(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Université de Montréal filed Critical Université de Montréal
Publication of LT2807165T publication Critical patent/LT2807165T/lt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LTEP13740815.9T 2012-01-27 2013-01-25 Pirimido[4,5-b]indolo dariniai ir jų panaudojimas kraujodaros kamieninių ląstelių dauginime LT2807165T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261591521P 2012-01-27 2012-01-27
PCT/CA2013/050052 WO2013110198A1 (en) 2012-01-27 2013-01-25 Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells

Publications (1)

Publication Number Publication Date
LT2807165T true LT2807165T (lt) 2019-07-25

Family

ID=48872865

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13740815.9T LT2807165T (lt) 2012-01-27 2013-01-25 Pirimido[4,5-b]indolo dariniai ir jų panaudojimas kraujodaros kamieninių ląstelių dauginime

Country Status (24)

Country Link
US (3) US9409906B2 (enExample)
EP (1) EP2807165B1 (enExample)
JP (1) JP6250556B2 (enExample)
KR (1) KR102098122B1 (enExample)
CN (1) CN104144931B (enExample)
AU (1) AU2013212457B2 (enExample)
BR (1) BR112014018524B1 (enExample)
CA (1) CA2862140C (enExample)
CY (1) CY1121799T1 (enExample)
DK (1) DK2807165T3 (enExample)
ES (1) ES2733946T3 (enExample)
HR (1) HRP20191189T1 (enExample)
HU (1) HUE044070T4 (enExample)
IL (1) IL233587B (enExample)
LT (1) LT2807165T (enExample)
NZ (1) NZ627188A (enExample)
PL (1) PL2807165T3 (enExample)
PT (1) PT2807165T (enExample)
RS (1) RS59002B1 (enExample)
SG (1) SG11201404241SA (enExample)
SI (1) SI2807165T1 (enExample)
SM (1) SMT201900360T1 (enExample)
TR (1) TR201909582T4 (enExample)
WO (1) WO2013110198A1 (enExample)

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JP6401773B2 (ja) * 2013-03-11 2018-10-10 ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン Betブロモドメイン阻害剤およびこれを用いる治療方法
US9757378B2 (en) 2013-05-17 2017-09-12 Universite De Montreal Methods to modulate acute myeloid leukemia stem/progenitor cell expansion and/or differentiation
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CN106414445B (zh) * 2014-04-22 2020-07-03 蒙特利尔大学 化合物及其在扩增造血干细胞和/或造血祖细胞中的应用
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BR112014018524A2 (pt) 2021-06-08
ES2733946T3 (es) 2019-12-03
SI2807165T1 (sl) 2019-08-30
US20150011543A1 (en) 2015-01-08
PT2807165T (pt) 2019-07-12
US20170334904A1 (en) 2017-11-23
SG11201404241SA (en) 2014-08-28
AU2013212457B2 (en) 2017-02-16
BR112014018524B1 (pt) 2023-03-28
RS59002B1 (sr) 2019-08-30
KR20140121454A (ko) 2014-10-15
HK1203945A1 (en) 2015-11-06
JP6250556B2 (ja) 2017-12-20
US10336747B2 (en) 2019-07-02
CA2862140A1 (en) 2013-08-01
AU2013212457A1 (en) 2014-09-18
WO2013110198A1 (en) 2013-08-01
EP2807165A4 (en) 2015-08-26
TR201909582T4 (tr) 2019-07-22
PL2807165T3 (pl) 2019-09-30
IL233587B (en) 2019-11-28
IL233587A0 (en) 2014-08-31
HUE044070T4 (hu) 2019-12-30
CN104144931A (zh) 2014-11-12
EP2807165A1 (en) 2014-12-03
JP2015504902A (ja) 2015-02-16
US20160222017A1 (en) 2016-08-04
HRP20191189T1 (hr) 2019-10-04
CN104144931B (zh) 2018-04-10
NZ627188A (en) 2015-12-24
KR102098122B1 (ko) 2020-04-07
CY1121799T1 (el) 2020-07-31
EP2807165B1 (en) 2019-05-15
CA2862140C (en) 2020-04-21
US9409906B2 (en) 2016-08-09
HUE044070T2 (hu) 2019-09-30
DK2807165T3 (da) 2019-07-15
SMT201900360T1 (it) 2019-07-11
BR112014018524A8 (pt) 2017-07-11

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