LT2069B - Alpha-arilo-4-/4,5-dihidro-3,5-diokso-1,2,4--triazino-2-(3h)-il/benzolacetonitrilu gavimo budas - Google Patents

Alpha-arilo-4-/4,5-dihidro-3,5-diokso-1,2,4--triazino-2-(3h)-il/benzolacetonitrilu gavimo budas

Info

Publication number
LT2069B
LT2069B LTRP370A LTRP370A LT2069B LT 2069 B LT2069 B LT 2069B LT RP370 A LTRP370 A LT RP370A LT RP370 A LTRP370 A LT RP370A LT 2069 B LT2069 B LT 2069B
Authority
LT
Lithuania
Prior art keywords
dioxo
alpha
benzolacetonitrill
dihidro
arilo
Prior art date
Application number
LTRP370A
Other languages
English (en)
Lithuanian (lt)
Inventor
Gustaaf Maria Boeckx
Alfons Herman Marg Raeymaekers
Victor Sipido
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LT2069B publication Critical patent/LT2069B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Lubricants (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
LTRP370A 1984-08-01 1993-02-26 Alpha-arilo-4-/4,5-dihidro-3,5-diokso-1,2,4--triazino-2-(3h)-il/benzolacetonitrilu gavimo budas LT2069B (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63653884A 1984-08-01 1984-08-01
SU853929257A SU1443799A3 (ru) 1984-08-01 1985-07-31 Способ получени @ -арил-4- @ 4,5-дигидро-3,5-диоксо-1,2,4-триазин-2-(3Н)-ил @ -бензолацетонитрилов

Publications (1)

Publication Number Publication Date
LT2069B true LT2069B (lt) 1993-06-15

Family

ID=24552347

Family Applications (1)

Application Number Title Priority Date Filing Date
LTRP370A LT2069B (lt) 1984-08-01 1993-02-26 Alpha-arilo-4-/4,5-dihidro-3,5-diokso-1,2,4--triazino-2-(3h)-il/benzolacetonitrilu gavimo budas

Country Status (36)

Country Link
EP (1) EP0170316B1 (fr)
JP (2) JPS6143176A (fr)
KR (1) KR870000787B1 (fr)
CN (1) CN1016687B (fr)
AT (1) ATE53206T1 (fr)
AU (1) AU579653B2 (fr)
BG (1) BG46599A3 (fr)
CA (2) CA1244024A (fr)
CY (1) CY1656A (fr)
CZ (1) CZ277962B6 (fr)
DE (1) DE3577984D1 (fr)
DK (1) DK166414B1 (fr)
DZ (1) DZ814A1 (fr)
EG (1) EG17589A (fr)
ES (2) ES8609284A1 (fr)
FI (1) FI90235C (fr)
GR (1) GR851837B (fr)
HK (1) HK68092A (fr)
HU (1) HU194191B (fr)
IE (1) IE58076B1 (fr)
IL (1) IL75962A (fr)
LT (1) LT2069B (fr)
LV (2) LV5027A3 (fr)
MA (1) MA20497A1 (fr)
NO (1) NO171634C (fr)
NZ (1) NZ212770A (fr)
PH (1) PH21137A (fr)
PL (1) PL147667B1 (fr)
PT (1) PT80903B (fr)
RO (1) RO92300B (fr)
SG (1) SG65992G (fr)
SK (1) SK557685A3 (fr)
SU (1) SU1443799A3 (fr)
ZA (1) ZA855793B (fr)
ZM (1) ZM5385A1 (fr)
ZW (1) ZW12385A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8602556A (pt) * 1984-06-12 1987-02-03 Fmc Corp Composto herbicida;composicao herbicida e processo para controlar o crescimento de plantas indesejadas
DE3531919A1 (de) * 1985-09-07 1987-03-19 Hoechst Ag Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
EP0364765A3 (fr) * 1988-10-08 1991-07-17 Bayer Ag 1,3,5-Triazinetriones substituées, procédé pour leur préparation et leur application contre des protozoaires parasitaires
DE58905324D1 (de) * 1989-01-09 1993-09-23 Bayer Ag Mittel gegen protozoen bei insekten.
EP0377903A3 (fr) * 1989-01-09 1991-07-17 Bayer Ag Des hexahydro-1,2,4-triazinediones substitués, procédés pour leur préparation, des intermédiaires et leur utilisation
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) * 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
EP0476439A1 (fr) * 1990-09-18 1992-03-25 Bayer Ag Triazine-1,2,4 diones substituées, procédé et produits intermédiaires pour leur préparation et leur utilisation
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
TR200000153T2 (tr) * 1997-07-10 2000-07-21 Janssen Pharmaceutica N.V. İl-5 inhibite eden 6-azaurasil türevleri.
US6867207B2 (en) 1997-07-10 2005-03-15 Janssen Pharmaceutica N.V. IL-5 inhibiting 6-azauracil derivatives
EP0987265A1 (fr) 1998-09-18 2000-03-22 Janssen Pharmaceutica N.V. Dérivés de 6-azauracile comme inhibitrices de l'interleukine-5
PL198205B1 (pl) 1998-12-18 2008-06-30 Janssen Pharmaceutica Nv Inhibitująca IL-5 pochodna 6-azauracylu, jej zastosowanie i sposób wytwarzania, kompozycja farmaceutyczna, sposób znaczenia in vitro receptora i sposób obrazowania in vitro narządu
ATE318811T1 (de) 1999-08-06 2006-03-15 Janssen Pharmaceutica Nv Interleukin-5 hemmende 6-azauracil derivate
CN101265238B (zh) * 2007-12-12 2010-06-16 重庆天极旅业有限公司 一种三嗪环衍生物的合成方法
CN101265216B (zh) * 2007-12-18 2012-06-27 重庆华邦胜凯制药有限公司 4-(取代乙氰基)-苯腙衍生物及其合成方法
CN102911080B (zh) * 2012-09-12 2015-01-21 衢州学院 一种制备2,6-二氯-α-(4-氯苯基)-4-硝基苯乙腈的方法
CN107746390B (zh) * 2017-11-21 2021-03-16 连云港市亚晖医药化工有限公司 抗球虫药地克珠利的制备方法
CN113999139A (zh) * 2021-12-03 2022-02-01 杭州臻峰科技有限公司 制备2，6-二氯-α-（4-氯代苯基） -4-硝基苯乙腈的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905971A (en) * 1971-03-29 1975-09-16 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
US3912723A (en) * 1971-03-29 1975-10-14 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
GB1448696A (en) * 1973-05-29 1976-09-08 Pfizer 2-phqnyl-astriazine-3,4-2h,4h-diones

Also Published As

Publication number Publication date
ES8705403A1 (es) 1987-05-01
IL75962A0 (en) 1985-12-31
FI90235B (fi) 1993-09-30
DE3577984D1 (de) 1990-07-05
HK68092A (en) 1992-09-18
NO853037L (no) 1986-02-03
PT80903A (en) 1985-09-01
JPH0517454A (ja) 1993-01-26
EP0170316A2 (fr) 1986-02-05
ATE53206T1 (de) 1990-06-15
AU579653B2 (en) 1988-12-01
PT80903B (pt) 1987-11-11
FI852958L (fi) 1986-02-02
CZ557685A3 (en) 1993-02-17
CY1656A (en) 1993-05-14
PH21137A (en) 1987-07-27
EP0170316B1 (fr) 1990-05-30
DK166414B1 (da) 1993-05-17
LV5772B4 (lv) 1997-06-20
NZ212770A (en) 1988-10-28
BG46599A3 (en) 1990-01-15
ES552443A0 (es) 1987-05-01
IE58076B1 (en) 1993-06-30
AU4566485A (en) 1986-02-06
CN85105673A (zh) 1987-01-14
CN1016687B (zh) 1992-05-20
ES545744A0 (es) 1986-07-16
KR870000787B1 (ko) 1987-04-18
NO171634C (no) 1993-04-14
FI852958A0 (fi) 1985-07-31
IE851911L (en) 1986-02-01
CZ277962B6 (en) 1993-07-14
DZ814A1 (en) 2004-09-13
KR860001796A (ko) 1986-03-22
HU194191B (en) 1988-01-28
JPS6143176A (ja) 1986-03-01
LV5772A4 (lv) 1996-12-20
HUT39433A (en) 1986-09-29
PL147667B1 (en) 1989-07-31
ZM5385A1 (en) 1987-03-27
EG17589A (en) 1991-12-30
SK278310B6 (en) 1996-09-04
PL254700A1 (en) 1986-09-23
ZA855793B (en) 1987-03-25
JPH0625177B2 (ja) 1994-04-06
LV5027A3 (lv) 1993-06-10
MA20497A1 (fr) 1986-04-01
IL75962A (en) 1989-09-28
DK347585A (da) 1986-02-02
FI90235C (fi) 1994-01-10
GR851837B (fr) 1985-12-02
SK557685A3 (en) 1996-09-04
DK347585D0 (da) 1985-07-31
ZW12385A1 (en) 1987-02-25
CA1305479C (fr) 1992-07-21
NO171634B (no) 1993-01-04
CA1244024A (fr) 1988-11-01
ES8609284A1 (es) 1986-07-16
RO92300B (ro) 1987-12-02
JPH0420435B2 (fr) 1992-04-02
SU1443799A3 (ru) 1988-12-07
RO92300A (fr) 1987-11-30
SG65992G (en) 1992-09-04
EP0170316A3 (en) 1986-11-05

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