KR950703659A - 보존된 g₄핵심서열을 갖는 올리고누클레오티드(oligonucleotioes having a conserved g₄core sequence) - Google Patents
보존된 g₄핵심서열을 갖는 올리고누클레오티드(oligonucleotioes having a conserved g₄core sequence)Info
- Publication number
- KR950703659A KR950703659A KR1019950701139A KR19950701139A KR950703659A KR 950703659 A KR950703659 A KR 950703659A KR 1019950701139 A KR1019950701139 A KR 1019950701139A KR 19950701139 A KR19950701139 A KR 19950701139A KR 950703659 A KR950703659 A KR 950703659A
- Authority
- KR
- South Korea
- Prior art keywords
- conserved
- sequence
- oligonucleotides
- telomere length
- oligonucleotioes
- Prior art date
Links
Classifications
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1133—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against herpetoviridae, e.g. HSV
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01004—Phospholipase A2 (3.1.1.4)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
- C12N2310/151—Nucleic acids forming more than 2 strands, e.g. TFOs more than 3 strands, e.g. tetrads, H-DNA
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/341—Gapmers, i.e. of the type ===---===
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95418592A | 1992-09-29 | 1992-09-29 | |
US7/954,185 | 1992-09-29 | ||
PCT/US1993/009297 WO1994008053A1 (en) | 1992-09-29 | 1993-09-29 | Oligonucleotides having a conserved g4 core sequence |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950703659A true KR950703659A (ko) | 1995-09-20 |
KR0172153B1 KR0172153B1 (ko) | 1999-02-01 |
Family
ID=25495059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950701139A KR0172153B1 (ko) | 1992-09-29 | 1993-09-29 | 보존된 g4 핵심 서열을 갖는 올리고누클레오티드 |
Country Status (15)
Country | Link |
---|---|
US (5) | US5523389A (ko) |
EP (2) | EP1016715A1 (ko) |
JP (1) | JP2818031B2 (ko) |
KR (1) | KR0172153B1 (ko) |
AT (1) | ATE222290T1 (ko) |
AU (1) | AU668604B2 (ko) |
BR (1) | BR1100614A (ko) |
CA (1) | CA2145664C (ko) |
DE (1) | DE69332206T2 (ko) |
FI (1) | FI951467A0 (ko) |
HU (1) | HUT70965A (ko) |
IL (1) | IL107150A0 (ko) |
NO (1) | NO951191L (ko) |
NZ (2) | NZ256787A (ko) |
WO (1) | WO1994008053A1 (ko) |
Families Citing this family (101)
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US6369209B1 (en) | 1999-05-03 | 2002-04-09 | Isis Pharmaceuticals, Inc. | Oligonucleotides having A-DNA form and B-DNA form conformational geometry |
US5489508A (en) * | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
US6007989A (en) | 1992-05-13 | 1999-12-28 | Board Of Regents, The University Of Texas System | Methods of screening for compounds that derepress or increase telomerase activity |
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US5830644A (en) * | 1992-05-13 | 1998-11-03 | Geron Corporation | Method for screening for agents which increase telomerase activity in a cell |
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US5989807A (en) * | 1992-05-13 | 1999-11-23 | Geron Corporation & Board Of Regents | Detecting cancerous conditions by assaying for telomerase activity |
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US5648215A (en) * | 1992-05-13 | 1997-07-15 | Board Of Regents, The University Of Texas System | Telomerase diagnostic methods |
US5686306A (en) * | 1992-05-13 | 1997-11-11 | Board Of Regents, The University Of Texas System | Methods and reagents for lengthening telomeres |
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EP0713705A4 (en) * | 1994-03-25 | 1998-09-02 | Akira Kaji | NEW ANTI-HIV MEDICINE |
AU3889595A (en) * | 1994-10-05 | 1996-05-02 | Amgen, Inc. | Method for inhibiting smooth muscle cell proliferation and oligonucleotides for use therein |
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US5741677A (en) * | 1995-06-07 | 1998-04-21 | Geron Corporation | Methods for measuring telomere length |
US6004939A (en) * | 1995-07-06 | 1999-12-21 | Ctrc Research Foundation Board Of Regents | Methods for modulation and inhibition of telomerase |
US6054442A (en) * | 1995-07-06 | 2000-04-25 | Board Of Regents, University Of Texas System | Methods and compositions for modulation and inhibition of telomerase in vitro |
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US5691145A (en) * | 1996-08-27 | 1997-11-25 | Becton, Dickinson And Company | Detection of nucleic acids using G-quartets |
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JP4627369B2 (ja) | 1998-06-10 | 2011-02-09 | バイオグノスティック ゲゼルシャフト フュア バイオモレキュラー ダイアグノスティック ミット ベシュレンクテル ハフツング | 免疫系を刺激する方法 |
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- 1993-09-29 AU AU51673/93A patent/AU668604B2/en not_active Expired
- 1993-09-29 WO PCT/US1993/009297 patent/WO1994008053A1/en active IP Right Grant
- 1993-09-29 US US08/403,888 patent/US5952490A/en not_active Expired - Lifetime
- 1993-09-29 CA CA002145664A patent/CA2145664C/en not_active Expired - Lifetime
- 1993-09-29 AT AT93922788T patent/ATE222290T1/de not_active IP Right Cessation
- 1993-09-29 KR KR1019950701139A patent/KR0172153B1/ko not_active IP Right Cessation
- 1993-09-29 EP EP99203835A patent/EP1016715A1/en not_active Withdrawn
- 1993-09-29 JP JP6509299A patent/JP2818031B2/ja not_active Expired - Lifetime
- 1993-09-29 DE DE69332206T patent/DE69332206T2/de not_active Expired - Lifetime
- 1993-09-29 HU HU9500911A patent/HUT70965A/hu unknown
- 1993-09-29 EP EP93922788A patent/EP0672193B1/en not_active Expired - Lifetime
-
1995
- 1995-03-27 NZ NZ256787A patent/NZ256787A/en not_active IP Right Cessation
- 1995-03-28 FI FI951467A patent/FI951467A0/fi unknown
- 1995-03-28 NO NO951191A patent/NO951191L/no unknown
-
1997
- 1997-02-17 NZ NZ314251A patent/NZ314251A/xx not_active IP Right Cessation
- 1997-05-13 BR BR1100614-5A patent/BR1100614A/pt active IP Right Grant
-
2006
- 2006-05-17 US US11/436,901 patent/US20070015723A1/en not_active Abandoned
- 2006-08-09 US US11/502,008 patent/US20070270363A1/en not_active Abandoned
-
2010
- 2010-08-04 US US12/849,886 patent/US20110124715A1/en not_active Abandoned
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US20070270363A1 (en) | 2007-11-22 |
US20070015723A1 (en) | 2007-01-18 |
HUT70965A (en) | 1995-11-28 |
DE69332206D1 (de) | 2002-09-19 |
EP0672193A1 (en) | 1995-09-20 |
WO1994008053A1 (en) | 1994-04-14 |
NO951191D0 (no) | 1995-03-28 |
BR1100614A (pt) | 2000-04-11 |
AU668604B2 (en) | 1996-05-09 |
JP2818031B2 (ja) | 1998-10-30 |
HU9500911D0 (en) | 1995-05-29 |
CA2145664A1 (en) | 1994-04-14 |
CA2145664C (en) | 2002-08-20 |
AU5167393A (en) | 1994-04-26 |
US5523389A (en) | 1996-06-04 |
NO951191L (no) | 1995-03-28 |
EP0672193A4 (en) | 1995-11-22 |
ATE222290T1 (de) | 2002-08-15 |
EP0672193B1 (en) | 2002-08-14 |
US5952490A (en) | 1999-09-14 |
KR0172153B1 (ko) | 1999-02-01 |
DE69332206T2 (de) | 2003-05-28 |
FI951467A (fi) | 1995-03-28 |
FI951467A0 (fi) | 1995-03-28 |
NZ256787A (en) | 1997-04-24 |
JPH08500738A (ja) | 1996-01-30 |
EP1016715A1 (en) | 2000-07-05 |
US20110124715A1 (en) | 2011-05-26 |
IL107150A0 (en) | 1993-12-28 |
NZ314251A (en) | 1999-05-28 |
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