KR20230090333A - 조성물 - Google Patents

조성물 Download PDF

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Publication number
KR20230090333A
KR20230090333A KR1020237015719A KR20237015719A KR20230090333A KR 20230090333 A KR20230090333 A KR 20230090333A KR 1020237015719 A KR1020237015719 A KR 1020237015719A KR 20237015719 A KR20237015719 A KR 20237015719A KR 20230090333 A KR20230090333 A KR 20230090333A
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KR
South Korea
Prior art keywords
group
compound
polymer
molecular weight
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237015719A
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English (en)
Korean (ko)
Inventor
신지 사쿠마
타쿠미 토모노
고헤이 미야타
코이치 시게노
Original Assignee
각코호우징 조쇼 가쿠엔
가부시키가이샤 아데카
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 각코호우징 조쇼 가쿠엔, 가부시키가이샤 아데카 filed Critical 각코호우징 조쇼 가쿠엔
Publication of KR20230090333A publication Critical patent/KR20230090333A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/36—Amides or imides
    • C08F222/38—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
KR1020237015719A 2020-10-16 2021-10-11 조성물 Pending KR20230090333A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020174704 2020-10-16
JPJP-P-2020-174704 2020-10-16
PCT/JP2021/037523 WO2022080294A1 (ja) 2020-10-16 2021-10-11 組成物

Publications (1)

Publication Number Publication Date
KR20230090333A true KR20230090333A (ko) 2023-06-21

Family

ID=81208159

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237015719A Pending KR20230090333A (ko) 2020-10-16 2021-10-11 조성물

Country Status (6)

Country Link
US (1) US20230383037A1 (https=)
EP (1) EP4230223A4 (https=)
JP (1) JPWO2022080294A1 (https=)
KR (1) KR20230090333A (https=)
CN (1) CN116507364A (https=)
WO (1) WO2022080294A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502667A (ja) 2006-09-07 2010-01-28 エフ．ホフマン−ラ ロシュ アーゲー Ｓｎａｃ（サルカプロザートナトリウム）の製造法
WO2010134537A1 (ja) 2009-05-20 2010-11-25 東レ株式会社 細胞膜透過性ペプチド
WO2016136708A1 (ja) 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチドを側鎖に有する高分子化合物
JP2019522020A (ja) 2016-04-06 2019-08-08 イファ ユニバーシティ−インダストリー コラボレーション ファウンデーションＥｗｈａ Ｕｎｉｖｅｒｓｉｔｙ − Ｉｎｄｕｓｔｒｙ Ｃｏｌｌａｂｏｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ 細胞膜に浸透する能力を有するペプチド

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4099831B2 (ja) 1994-07-14 2008-06-11 昭和電工株式会社 高重合性ｎ−ビニルカルボン酸アミドおよびその製造方法
JP5281358B2 (ja) * 2008-10-27 2013-09-04 学校法人常翔学園 高分子、経上皮吸収促進剤、及び医薬用製剤
JP5808082B2 (ja) * 2010-04-30 2015-11-10 株式会社Adeka 細胞への水溶性高分子量物質の導入方法及び導入剤
CN107207627B (zh) * 2015-02-27 2022-05-24 学校法人常翔学园 具有膜透过性肽链的多糖衍生物
CN112424239B (zh) * 2018-07-11 2023-12-05 学校法人常翔学园 高分子化合物及使用了该高分子化合物的细胞内化合物导入促进剂

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502667A (ja) 2006-09-07 2010-01-28 エフ．ホフマン−ラ ロシュ アーゲー Ｓｎａｃ（サルカプロザートナトリウム）の製造法
WO2010134537A1 (ja) 2009-05-20 2010-11-25 東レ株式会社 細胞膜透過性ペプチド
WO2016136708A1 (ja) 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチドを側鎖に有する高分子化合物
JP2019522020A (ja) 2016-04-06 2019-08-08 イファ ユニバーシティ−インダストリー コラボレーション ファウンデーションＥｗｈａ Ｕｎｉｖｅｒｓｉｔｙ − Ｉｎｄｕｓｔｒｙ Ｃｏｌｌａｂｏｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ 細胞膜に浸透する能力を有するペプチド

Also Published As

Publication number Publication date
US20230383037A1 (en) 2023-11-30
CN116507364A (zh) 2023-07-28
EP4230223A1 (en) 2023-08-23
JPWO2022080294A1 (https=) 2022-04-21
EP4230223A4 (en) 2025-03-05
WO2022080294A1 (ja) 2022-04-21

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Patent event date: 20230509

Patent event code: PA01051R01D

Comment text: International Patent Application

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Patent event code: PA02012R01D

Patent event date: 20240812

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