JPWO2022080294A1 - - Google Patents

Info

Publication number
JPWO2022080294A1
JPWO2022080294A1 JP2022556954A JP2022556954A JPWO2022080294A1 JP WO2022080294 A1 JPWO2022080294 A1 JP WO2022080294A1 JP 2022556954 A JP2022556954 A JP 2022556954A JP 2022556954 A JP2022556954 A JP 2022556954A JP WO2022080294 A1 JPWO2022080294 A1 JP WO2022080294A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022556954A
Other languages
Japanese (ja)
Other versions
JPWO2022080294A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2022080294A1 publication Critical patent/JPWO2022080294A1/ja
Publication of JPWO2022080294A5 publication Critical patent/JPWO2022080294A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/36Amides or imides
    • C08F222/38Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2022556954A 2020-10-16 2021-10-11 Pending JPWO2022080294A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020174704 2020-10-16
PCT/JP2021/037523 WO2022080294A1 (ja) 2020-10-16 2021-10-11 組成物

Publications (2)

Publication Number Publication Date
JPWO2022080294A1 true JPWO2022080294A1 (https=) 2022-04-21
JPWO2022080294A5 JPWO2022080294A5 (https=) 2024-10-07

Family

ID=81208159

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022556954A Pending JPWO2022080294A1 (https=) 2020-10-16 2021-10-11

Country Status (6)

Country Link
US (1) US20230383037A1 (https=)
EP (1) EP4230223A4 (https=)
JP (1) JPWO2022080294A1 (https=)
KR (1) KR20230090333A (https=)
CN (1) CN116507364A (https=)
WO (1) WO2022080294A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010100781A (ja) * 2008-10-27 2010-05-06 Josho Gakuen 高分子、経上皮吸収促進剤、及び医薬用製剤
JP2011229495A (ja) * 2010-04-30 2011-11-17 Adeka Corp 細胞への水溶性高分子量物質の導入方法及び導入剤
WO2016136707A1 (ja) * 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチド鎖を有する多糖誘導体
WO2016136708A1 (ja) * 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチドを側鎖に有する高分子化合物
WO2020013265A1 (ja) * 2018-07-11 2020-01-16 学校法人常翔学園 高分子化合物及びそれを用いた細胞内化合物導入促進剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4099831B2 (ja) 1994-07-14 2008-06-11 昭和電工株式会社 高重合性n−ビニルカルボン酸アミドおよびその製造方法
BRPI0716539A2 (pt) 2006-09-07 2016-11-01 Emisphere Tech Inc métodos para sintetização de ácido n-(8-[2-hidroxibenzoil]amino) caprílico e de sal de sódio deste
RU2548807C2 (ru) 2009-05-20 2015-04-20 Торэй Индастриз, Инк. Пептиды, проникающие в клетку
US10918727B2 (en) 2016-04-06 2021-02-16 Icure Bnp Co., Ltd. Peptide with ability to penetrate cell membrane

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010100781A (ja) * 2008-10-27 2010-05-06 Josho Gakuen 高分子、経上皮吸収促進剤、及び医薬用製剤
JP2011229495A (ja) * 2010-04-30 2011-11-17 Adeka Corp 細胞への水溶性高分子量物質の導入方法及び導入剤
WO2016136707A1 (ja) * 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチド鎖を有する多糖誘導体
WO2016136708A1 (ja) * 2015-02-27 2016-09-01 学校法人常翔学園 膜透過性ペプチドを側鎖に有する高分子化合物
WO2020013265A1 (ja) * 2018-07-11 2020-01-16 学校法人常翔学園 高分子化合物及びそれを用いた細胞内化合物導入促進剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
佐久間信至、日渡謙一郎: "オリゴアルギニン固定化高分子を用いた低膜透過性分子の細胞膜透過促進", DRUG DELIVERY SYSTEM, vol. Vol.28-2, JPN6021047554, 2013, pages 109 - 118, ISSN: 0005702683 *
田原章寛 ET AL.: "膜透過ペプチド固定化ヒアルロン酸を用いた抗体医薬の経鼻吸収促進", 第35回日本薬剤学会年会講演要旨集, JPN6021047553, 8 May 2020 (2020-05-08), pages 170 - 2, ISSN: 0005828388 *

Also Published As

Publication number Publication date
US20230383037A1 (en) 2023-11-30
KR20230090333A (ko) 2023-06-21
CN116507364A (zh) 2023-07-28
EP4230223A1 (en) 2023-08-23
EP4230223A4 (en) 2025-03-05
WO2022080294A1 (ja) 2022-04-21

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