KR20180082435A - 박테리아 균주를 함유한 조성물 - Google Patents
박테리아 균주를 함유한 조성물 Download PDFInfo
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Abstract
본 개시내용은 염증성 및 자가면역성 질환을 치료 또는 예방하기 위한 박테리아 균주를 포함하는 조성물을 제공한다.
Description
본 발명은 포유동물의 소화관으로부터 단리된 박테리아 균주를 포함하는 조성물 분야 및 상기 조성물의 질병 치료에서의 용도에 관한 것이다.
인간의 장은 자궁에서 무균으로 여겨지지만 태어난 직후에는 매우 다양한 모성 및 환경 미생물에 노출된다. 그 후, 미생물 콜로니와 승계의 역동적인 기간이 발생하며, 이는 수송 방식, 환경, 식이 및 숙주 유전형과 같은 요인에 의해 영향을 받으며, 이들 모두는 특히 초기 생애 동안 소화관 미생물의 조성에 영향을 미친다. 결과적으로, 미생물은 안정화되고 성체와 같이 된다[1]. 인간 장내 미생물은 본질적으로 두 개의 주요 박테리아 분류인 박테리오데테스(Bacteroidetes)와 피르미쿠테스(Firmicutes)에 속하는 500 내지 1000 가지 이상의 다른 계통형(phylotype)을 함유한다[2]. 인간 장내 박테리아 콜로니에서 발생하는 성공적인 공생 관계는 다양한 신진대사, 구조적, 보호 및 기타 유익한 기능을 제공한다. 콜로니화된 장내 신진대사 활동이 강화되면 소화불량 식이 성분이 부산물을 방출하여 숙주에게 중요한 영양 공급원을 제공한다. 유사하게, 장내 미생물의 면역학적 중요성은 잘 알려져 있으며, 공생 박테리아의 도입에 따라 기능적으로 재구성된 면역 체계가 손상된 무균 동물에서 예시된다[3-5].
미생물 조성의 급격한 변화는 염증성 장 질환(IBD)과 같은 위장 장애에서 입증되었다. 예를 들어, IBD 환자에서 클로스트리디움 클러스터 XIVa 박테리아의 수치가 감소하는 반면 대장균 수가 증가하여 장내에서 공생균(symbionts)과 유해균(pathobionts)의 균형이 바뀌었다고 나타났다[6-9]. 흥미롭게도, 이러한 미생물 부조화는 또한 T 효과기 세포 집단내 불균형과 관련된다.
특정 박테리아 균주가 동물 장내에 미칠 수 있는 잠재적인 긍정적인 효과를 인식하여 다양한 질병의 치료에 다양한 균주가 제안되었다(예를 들어 [10-13] 참조). 또한 대부분 락토바실러스(Lactobacillus) 와 비티도박테리움(Bifidobacterium) 균주 를 포함한 특정 균주는 장에 직접 연결되지 않은 다양한 염증성 및 자가면역 질환의 치료에 사용하기 위해 제안되었다(문헌 [14] 및 [15] 참조). 그러나 다른 질병과 다른 박테리아 균주 사이의 관계, 특정 박테리아 균주가 장내와 전신 수준 및 특정 질병 유형에 미치는 정확한 효과에 대해서는 잘 알려져 있지 않다.
Seres Health, Inc.(참조 [16])은 대변 샘플로부터 수득된 박테리아가 면역계 장애의 치료에 유용할 수 있다고 예상하지만 박테리아가 효과적일 것이라는 지도가 제공되지 않는다.
Honda 등(참조 [17])은 클로스트리듐 속으로부터 종을 포함하는, 상이한 속의 20 박테리아의 혼합물이 Th17 세포의 증식 및 축적을 유도하는 방법을 기재한다. Honda 등의 조성물은 면역 기능의 개선 및 감염성 질환의 예방 또는 치료에 유용한 것으로 언급된다. 그러나, Honda 등은 개체에서 자가면역 및 염증성 질환을 치료하기 위해, Th17-유도 박테리아가, 예를 들어, 환자에 항생제 투여에 의해 억제 또는 사멸되어야 한다는 것을 교시한다.
염증 및 자가면역 질환을 치료하는 새로운 방법에 대한 요구가 있다. 장내 박테리아를 이용한 새로운 치료법을 개발할 수 있도록 장내 박테리아의 잠재적인 효과에 대한 요건도 있다.
본 발명자들은 염증 및 자가면역 질환을 치료하고 예방하기 위한 새로운 치료법을 개발하였다. 특히, 본 발명자들은 IL-17 또는 Th17 경로에 의해 매개되는 질병 및 병태를 치료 및 예방하기 위한 새로운 치료법을 개발하였다. 특히, 본 발명자들은 속 에리시펠라토클로스트리디움(Erysipelatoclostridium) 으로부터 박테리아 균주가 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 및 예방에 효과적일 수 있다는 것을 확인하였다. 실시예에서 기재된 대로, 에리시펠라토클로스트리디움 라모숨(Erysipelatoclostridium ramosum)을 포함하는 조성물의 경구 투여는 포도막염의 마우스 모델에서 Th17 염증 반응을 포함하는 염증 반응의 중증도를 감소시킬 수 있다.
따라서, 제1 구현예에서, 본 발명은, IL-17 또는 Th17 경로에 의해 매개된 질환 또는 병태의 치료 또는 예방하는 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 본 발명자들은 상기 종으로부터 박테리아 균주로 치료가 IL-17 및 Th17 경로에 의해 매개된 염증성 및 자가면역 질환의 마우스 모델에서 임상 이득을 제공할 수 있고, IL-17을 포함하는, Th17 경로의 일부인 사이토카인의 수준을 감소시킬 수 있고, Th17 염증 반응을 경감시킬 수 있다는 것을 확인하였다.
특정한 구현예에서, 본 발명은, 하기로 이루어진 군으로부터 선택된 질환 또는 병태의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다:포도막염; 암, 예컨대 유방암, 폐암, 간암, 결장암, 또는 난소암; 다발성 경화증; 관절염, 예컨대 류마티스성 관절염, 골관절염, 건선성 관절염, 또는 유년성 특발성 관절염; 시신경척수염 (데빅병); 강직 척추염; 척추관절염; 건선; 전신 홍반성 낭창; 염증성 장 질환, 예컨대 크론병 또는 궤양성 대장염; 소아지방변증; 천식, 예컨대 알러지성 천식 또는 호중구성 천식; 만성 폐쇄성 폐 질환 (COPD); 공막염; 혈관염; 베체트병; 죽상경화증; 아토피 피부염; 폐공기증; 치주염; 알러지성 비염; 및 동종이식편 거부반응.Th17 염증 반응에서 및 IL-17 및 Th17 경로에 의해 매개된 질환에서 속 에리시펠라토클로스트리디움 으로부터 박테리아 균주에 대하여 나타난 효과는 IL-17 및 Th17 경로에 의해 매개된 다른 질환 및 병태에 치료 이점, 예컨대 상기 열거된 것을 제공한다.
특히 바람직한 구현예에서, 본 발명은, 포도막염, 예컨대 후측 포도막염의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 본 발명자들은 에리시펠라토클로스트리디움 균주로 치료가 포도막염의 마우스 모델에서 질환 발병률 및 질환 중증도를 감소시킬 수 있고 망막 손상을 예방 또는 감소시킬 수 있다는 것을 확인하였다. 바람직한 구현예에서, 본 발명은, 포도막염의 치료에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 라모숨 을 이용하는 조성물은 포도막염 치료에 특히 효과적일 수 있다.
추가로 바람직한 구현예에서, 본 발명은, 천식, 예컨대 호중구성 천식 또는 알러지성 천식의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 균주로 치료는, 천식의 치료 또는 예방을 도울 수 있는, 폐 속에 호중구 및 호산구의 동원을 감소시킬 수 있다. 특정 구현예에서, 조성물은 호중구성 천식 또는 호산구성 천식을 치료 또는 예방하는 방법에 사용하기 위한 것이다. 본 발명의 조성물은 호중구성 천식 및 호산구성 천식의 치료 또는 예방에 특히 효과적일 수 있다. 실제로, 특정 구현예에서, 조성물은 천식의 치료 또는 예방에서 호중구성 염증 반응을 감소시키는 방법에 사용하기 위한 것이거나, 조성물은 천식의 치료 또는 예방에서 호산구성 염증 반응을 감소시키는 방법에 사용하기 위한 것이다. 바람직한 구현예에서, 본 발명은 천식, 및 특히 호산구성 또는 알러지성 천식의 치료에 사용하기 위한 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다. 또한, 에리시펠라토클로스트리디움 라모숨 은 천식 모델의 중성구에서 특히 확연한 효과를 가질 수 있고 에리시펠라토클로스트리디움 라모숨 으로 치료는 호중구성 천식 치료에 특히 효과적일 수 있다.
추가로 바람직한 구현예에서, 본 발명은, 류마티스성 관절염의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 균주로 치료는 류마티스성 관절염의 마우스 모델에서 임상 이득을 제공할 수 있고 관절 팽윤을 감소시킬 수 있다. 바람직한 구현예에서, 본 발명은, 류마티스성 관절염의 치료에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 라모숨 을 이용하는 조성물은 류마티스성 관절염 치료에 특히 효과적일 수 있다.
추가로 바람직한 구현예에서, 본 발명은, 다발성 경화증의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 균주로 치료는 다발성 경화증의 마우스 모델에서 질환 발병률 및 질환 중증도를 감소시킬 수 있다. 바람직한 구현예에서, 본 발명은, 다발성 경화증의 치료에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다. 에리시펠라토클로스트리디움 라모숨 을 이용하는 조성물은 다발성 경화증 치료에 특히 효과적일 수 있다.
추가로 바람직한 구현예에서, 본 발명은, 암, 예컨대 유방, 폐 또는 간 암의 치료 또는 예방의 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 제공한다. 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물은 유방, 폐 및 간 암의 마우스 모델에서 종양 성장을 감소시킬 수 있다. 특정 구현예에서, 조성물은 암 치료에서 종양 크기를 감소시키거나 종양 성장을 예방하는 방법에 사용하기 위한 것이다. 특정 구현예에서, 본 발명은, 암의 치료에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다.
특정 구현예에서, 본 발명의 조성물은 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태의 치료 또는 예방에서 IL-17 생산을 감소시키거나 Th17 세포 분화를 감소시키는 방법에 사용하기 위한 것이다. 특히, 본 발명의 조성물은 천식, 류마티스성 관절염, 다발성 경화증, 포도막염 또는 암의 치료 또는 예방에서 IL-17 생산 감소 또는 Th17 세포 분화 감소에 사용될 수 있다. 바람직하게는, 본 발명은, 천식, 류마티스성 관절염, 다발성 경화증, 포도막염 또는 암의 치료 또는 예방에서 IL-17 생산 감소 또는 Th17 세포 분화 감소에 사용하기 위한, 속 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다.
특정 구현예에서, 조성물은 증가된 IL-17 수준 또는 Th17 세포를 갖는 환자에 사용하기 위한 것이다. Th17 염증 반응과 강력하게 관련되는, 포도막염에서 에리시펠라토클로스트리디움 균주에 대하여 나타난 효과는 에리시펠라토클로스트리디움 균주가 상기 환자에 특히 유익할 수 있다는 것을 의미한다.
본 발명의 바람직한 구현예에서, 조성물에서 박테리아 균주는 에리시펠라토클로스트리디움 라모숨의 것이다. 밀접하게 관련된 균주, 예컨대 에리시펠라토클로스트리디움 라모숨의 박테리아 균주의 16s rRNA 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는 박테리아 균주가 또한 사용될 수 있다. 바람직하게는, 박테리아 균주는 서열 식별 번호: 1, 2 또는 3에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는다. 바람직하게는, 서열 동일성 서열 식별 번호: 3에 대한 것이다. 바람직하게는, 본 발명에서 사용하기 위한 박테리아 균주는 서열번호: 3으로 표시되는 16s rRNA 서열을 갖는다.
특정 구현예에서, 본 발명의 조성물은 경구 투여를 위한 것이다. 본 발명의 균주의 경구 투여는 IL-17 또는 Th17 경로-매개 질병 및 병태의 치료에 효과적일 수 있다. 또한, 경구 투여는 환자 및 종사자에게 편리하며 장내 수송 및/또는 부분적 또는 전체 콜로니화를 허용한다.
특정 구현예에서, 본 발명의 조성물은 하나 이상의 약학적으로 허용가능한 부형제 또는 담체를 포함한다.
특정 구현예에서, 본 발명의 조성물은 동결 건조된 박테리아 균주를 포함한다. 동결 건조는 박테리아의 수송을 허용하는 안정한 조성물을 제조하기 위한 효과적이고 편리한 기술이다.
특정 구현예에서, 본 발명은 상기 기재된 조성물을 포함하는 식품을 제공한다.
특정 구현예에서, 본 발명은 전술한 바와 같은 조성물을 포함하는 백신 조성물을 제공한다.
추가적으로, 본 발명은, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물의 투여를 포함하는, IL-17 또는 Th17 경로에 의해 매개된 질환 또는 병태의 치료 또는 예방 방법을 제공한다.
상기 발명을 개발함에 있어서, 본 발명자들은 치료에 특히 유용한 박테리아 균주를 확인 및 특성화하였다. 본 발명의 에리시펠라토클로스트리디움 라모숨 균주는 본원에서 기재된 질환, 예컨대 포도막염의 치료에 효과적인 것으로 나타난다. 따라서, 또 다른 측면에서, 본 발명은 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), 또는 이의 유도체의 세포를 제공한다. 본 발명은 또한 이러한 세포를 포함하는 조성물 또는 이러한 세포의 생물학적으로 순수한 배양물을 제공한다. 본 발명은 또한 치료법에서, 특히 본원에서 기재된 질환에 대하여 사용하기 위한, 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), 또는 이의 유도체의 세포를 제공한다.
도 1: 포도막염의 마우스 모델 - 대조군 그룹에서 TEFI 스코어.데이터는 평균± SEM으로 표시된다.
도 2: 포도막염의 마우스 모델 - 28 일째에 TEFI 스코어.데이터는 평균± SEM으로 표시된다.
도 2: 포도막염의 마우스 모델 - 28 일째에 TEFI 스코어.데이터는 평균± SEM으로 표시된다.
박테리아 균주
본 발명의 조성물은 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함한다. 그 예는 상기 속의 박테리아가 포도막염 및 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 유용하다는 것을 입증한다. 바람직한 박테리아 균주는 종 에리시펠라토클로스트리디움 라모숨의 것이다.
본 발명은, 치료법에 사용하기 위한, 예를 들어, 염증성 및/또는 자가면역 질환의 치료 또는 예방에 사용하기 위한, 에리시펠라토클로스트리디움, 예를 들어, 에리시펠라토클로스트리디움 라모숨을 제공한다. 유사하게, 본 발명은, 치료법에 사용하기 위한, 예를 들어, 염증성 및/또는 자가면역 질환의 치료 또는 예방에 사용하기 위한, 속 에리시펠라토클로스트리디움, 예를 들어, 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는 조성물을 제공한다. 특정 구현예에서, 본 발명의 조성물은 에리시펠라토클로스트리디움, 예를 들어, 에리시펠라토클로스트리디움 라모숨을 포함하고, 임의의 다른 박테리아 속을 함유하지 않는다. 특정 구현예에서, 본 발명의 조성물은 단일 종의 에리시펠라토클로스트리디움, 예를 들어, 에리시펠라토클로스트리디움 라모숨을 포함하고, 임의의 다른 박테리아 종을 함유하지 않는다. 특정 구현예에서, 본 발명의 조성물은 단일 균주의 에리시펠라토클로스트리디움, 예를 들어, 에리시펠라토클로스트리디움 라모숨을 포함하고, 임의의 다른 박테리아 균주 또는 종을 함유하지 않는다.
본 발명에 사용하기 위한 에리시펠라토클로스트리디움 종의 예는 하기를 포함한다: 에리시펠라토클로스트리디움 라모숨, (클로스트리듐) 코클레아툼, (C.) 사카로구미아, (C.) 스피로포르메, 및 (C.) 인노쿠움 ([18]에서 최근에 재분류됨). 에리시펠라토클로스트리디움은 그램-양성 염색한, 비-운동성, 절대적 혐기성 선형 또는 나선으로 만곡된 0.3-1.0 μm×2-4 μm의 로드(rod)이다. 포자 형성은 희귀하거나 결여된다. 따라서, 본 발명의 일부 구현예에서, 에리시펠라토클로스트리디움 박테리아 균주는 포자형성된 형태가 아니거나 임의의 포자가 존재하면 이들은 최소한 양으로 존재한다. 게놈 DNA의 G+C 함량은 27-33 mol%이다. 이들은 글루코스, 푸룩토오스 및 수크로오스 [18]를 발효시킨다. 에리시펠라토클로스트리디움 라모숨의 균주 유형은 ATCC 25582 = DSM 1402이다. 에리시펠라토클로스트리디움 라모숨 균주 DSM 1402의 16S rRNA 유전자 서열에 대한 유전자은행 수탁 번호는 (서열 식별 번호: 1로서 본원에서 개시된) X73440이다. 예시적인 에리시펠라토클로스트리디움 라모숨 균주는 [18]에 기재된다. 본 발명에 사용하기 위한 또 다른 균주는 에리시펠라토클로스트리디움 라모숨 균주 JCM 1298이다. 에리시펠라토클로스트리디움 라모숨 균주 JCM 1298의 16S rRNA 유전자 서열에 대한 유전자은행 수탁 번호는 (서열 식별 번호: 2로서 본원에서 개시된) NR_113243.1이다.
실시예에서 시험된 에리시펠라토클로스트리디움 라모숨 박테리움은 본원에서 균주 MRX027로서 참조된다. 시험된 MRX027 균주에 대한 16S rRNA 서열은 서열 식별 번호: 3에 제공된다. 균주 MRX027은 국제 수탁기관 NCIMB, Ltd.에 기탁되었고:(Ferguson Building, Aberdeen, AB21 9YA, Scotland) (4D Pharma Research Ltd.에 의해)(Life Sciences Innovation Building, Aberdeen, AB25 2ZS, Scotland) (2016년 11월 15일에) 수탁 번호 NCIMB 42688로 배정되었다. 용어들 “MRX027” 및 “MRx0027”은 본원에서 상호교환적으로 사용된다.
실시예에서 시험된 균주와 밀접하게 관련된 박테리아 균주는 포도막염 및 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적인 것으로 또한 예상된다. 특정 구현예에서, 본 발명에서 사용하기 위한 박테리아 균주는 에리시펠라토클로스트리디움 라모숨의 박테리아 균주의 16s rRNA 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는다. 바람직하게는, 본 발명에서 사용하기 위한 박테리아 균주는 서열 식별 번호: 1, 2 또는 3에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는다. 바람직하게는, 서열 동일성 서열 식별 번호: 3에 대한 것이다. 바람직하게는, 본 발명에서 사용하기 위한 박테리아 균주는 서열번호: 3으로 표시되는 16s rRNA 서열을 갖는다.
균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 및 JCM 1298의 생물형인 박테리아 균주는 포도막염 및 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적인 것으로 또한 예상된다. 생물형은 동일한 또는 매우 유사한 생리적 및 생화학적 특징을 갖는 밀접하게 관련된 균주이다.
균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298의 생물형인 그리고 본 발명에서 사용하기에 적합한 균주는 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298용 다른 뉴클레오타이드 서열의 서열분석에 의해 확인될 수 있다. 예를 들어, 실질적으로 전체의 게놈은 서열분석될 수 있고 본 발명에서 사용하기 위한 생물형 균주는 그의 전체의 게놈의 적어도 80%에 걸쳐 (예를 들면 적어도 85%, 90%, 95% 또는 99%, 또는 그의 전체의 게놈에 걸쳐) 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 서열 동일성을 가질 수 있다. 예를 들어, 일부 구현예에서, 생물형 균주는 그의 게놈의 적어도 98%에 걸쳐 적어도 98% 서열 동일성 또는 그의 게놈의 99%에 걸쳐 적어도 99% 서열 동일성을 갖는다. 생물형 균주 확인에서 사용하기 위한 다른 적합한 서열은 hsp60 또는 반복적인 서열 예컨대 BOX, ERIC, (GTG)5, 또는 REP 또는 [19]를 포함할 수 있다. 생물형 균주는 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298의 대응하는 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 서열 동일성을 가진 서열을 가질 수 있다. 일부 구현예에서, 생물형 균주는 NCIMB 42688로서 기탁된 균주 MRX027의 대응하는 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 서열 동일성을 가진 서열을 갖고 서열 식별 번호: 3에 적어도 99% 동일한 (예를 들면 적어도 99.5% 또는 적어도 99.9% 동일한) 16S rRNA 서열을 포함한다. 일부 구현예에서, 생물형 균주는 NCIMB 42688로서 기탁된 균주 MRX027의 대응하는 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 서열 동일성을 가진 서열을 갖고 서열 식별 번호: 3의 16S rRNA 서열을 갖는다.
대안적으로, 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298의 생물형인 그리고 본 발명에서 사용하기에 적합한 균주는 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298 및 제한 단편 분석 및/또는 PCR 분석의 이용에 의해, 예를 들어 형광 증폭된 단편 길이 다형성 (FAFLP) 및 반복적인 DNA 요소 (rep)-PCR 지문화, 또는 단백질 프로파일링, 또는 부분적인 16S 또는 23s rDNA 서열분석 이용에 의해 확인될 수 있다. 바람직한 구현예에서, 상기 기술은 다른 에리시펠라토클로스트리디움 라모숨 균주를 확인하는 데 사용될 수 있다.
특정 구현예에서, 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298의 생물형인 그리고 본 발명에서 사용하기에 적합한 균주는 증폭된 리보솜 DNA 제한 분석 (ARDRA)에 의해 분석된 경우, 예를 들어 Sau3AI 제한 효소를 이용한 경우 (예시적인 방법 및 지도에 대하여 참고, 예를 들어, [20]) 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298과 동일한 패턴을 제공하는 균주이다. 대안적으로, 생물형 균주는 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298과 동일한 탄수화물 발효 패턴을 갖는 균주로서 확인된다.
본 발명의 조성물 및 방법에서 유용한 다른 에리시펠라토클로스트리디움 라모숨 균주, 예컨대 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298의 생물형은, 실시예에서 기재된 검정을 포함하는, 임의의 적절한 방법 또는 전략을 이용하여 확인될 수 있다. 예를 들면, 본 발명에서 사용하기 위한 균주는 혐기성 YCFA에서 배양 및/또는 2형 콜라겐-유도된 관절염 마우스 모델에 박테리아 투여 및 그 다음 사이토카인 수준 평가에 의해 확인될 수 있다. 특히, 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298과 유사한 성장 패턴, 대사 유형 및/또는 표면 항원을 갖는 박테리아 균주는 본 발명에서 유용할 수 있다. 유용한 균주는 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), ATCC 25582 또는 JCM 1298과 비교할만한 면역 조절 활성을 가질 것이다. 특히, 생물형 균주는, 실시예에서 기재된 배양 및 투여 프로토콜을 이용함으로써 확인될 수 있는, 실시예에서 나타난 효과에 포도막염 질환 모델에서 비교할만한 효과를 유도할 것이다.
본 발명의 특히 바람직한 균주는 균주 MRX027 균주 (특히 NCIMB 42688로서 기탁된 MRX027)이다. 이것은 실시예에서 시험된 예시적인 균주이고 질환 치료에 효과적인 것으로 나타난다. 따라서, 본 발명은 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), 또는 이의 유도체의 세포, 예컨대 단리된 세포를 제공한다. 본 발명은 또한 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), 또는 이의 유도체의 세포를 포함하는 조성물을 제공한다. 본 발명은 또한 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027)의 생물학적으로 순수한 배양물을 제공한다. 본 발명은 또한 치료법에서, 특히 본원에서 기재된 질환에 대하여 사용하기 위한, 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027), 또는 이의 유도체의 세포를 제공한다. 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027)의 유도체는 딸 균주 (자손) 또는 최초로부터 배양된 (아클론화된) 균주일 수 있다.
본 발명의 균주 유도체는 생물학적 활성을 제거하지 않고 예를 들어 유전자 수준에서 변형될 수 있다. 특히, 본 발명의 유도체 균주는 치료적으로 활성이다. 유도체 균주는 에리시펠라토클로스트리디움 라모숨 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027)에 비교할만한 면역 조절 활성을 가질 것이다. 특히, 유도체 균주는, 실시예에서 기재된 배양 및 투여 프로토콜을 이용함으로써 확인될 수 있는, 실시예에서 나타난 효과에 포도막염 질환 모델에서 비교할만한 효과를 유도할 것이다. 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027)의 유도체는 일반적으로 균주 MRX027 (특히 NCIMB 42688로서 기탁된 MRX027)의 생물형일 것이다.
에리시펠라토클로스트리디움 라모숨 균주 MRX027의 세포에 대한 참고문헌은 균주 MRX027과 동일한 안전성 및 치료 효능 특징을 갖는 임의의 세포를 포함하고, 상기 세포는 본 발명에 의해 포함된다. NCIMB 42688로서 기탁된 MRX027에 대한 참고문헌은 기탁된 MRX027 균주만을 지칭한다.
에리시펠라토클로스트리디움 라모숨 균주 DSM 1402의 게놈 서열은 서열 식별 번호: 4로서 본원에서 개시된다. 상기 서열은 전체의 게놈 샷건 서열분석을 이용하여 수득된 게놈 스캐폴드이고 유전자은행 수탁 번호 NZ_DS499659.1을 이용하여 또한 이용가능하다. 특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4에 서열 동일성을 가진 염색체를 갖는다. 일부 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4의 적어도 30%에 걸쳐 (예를 들면 적어도 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 95%, 96%, 97%, 98%, 99% 또는 100%에 걸쳐) 서열 식별 번호: 4에 적어도 90% 서열 동일성 (예를 들면 적어도 92%, 94%, 95%, 96%, 97%, 98%, 99% 또는 100% 서열 동일성)을 가진 염색체를 갖는다. 예를 들어, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4의 35%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 45%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 70%에 걸쳐 서열 식별 번호: 4에 적어도 90% 서열 동일성, 또는 서열 식별 번호: 4의 80%에 걸쳐 서열 식별 번호: 4에 적어도 90% 서열 동일성, 또는 서열 식별 번호: 4의 90%에 걸쳐 서열 식별 번호: 4에 적어도 90% 서열 동일성, 또는 서열 식별 번호: 4의 100%에 걸쳐 서열 식별 번호: 4에 적어도 90% 서열 동일성, 또는 서열 식별 번호: 4의 70%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 80%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 90%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 100%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성, 또는 서열 식별 번호: 4의 70%에 걸쳐 서열 식별 번호: 4에 적어도 98% 서열 동일성, 또는 서열 식별 번호: 4의 80%에 걸쳐 서열 식별 번호: 4에 적어도 98% 서열 동일성, 또는 서열 식별 번호: 4의 90%에 걸쳐 서열 식별 번호: 4에 적어도 98% 서열 동일성, 또는 서열 식별 번호: 4의 95%에 걸쳐 적어도 98% 동일성, 또는 서열 식별 번호: 4의 100%에 걸쳐 서열 식별 번호: 4에 적어도 98% 서열 동일성, 또는 서열 식별 번호: 4의 90%에 걸쳐 서열 식별 번호: 4에 적어도 99.5% 서열 동일성, 또는 서열 식별 번호: 4의 95%에 걸쳐 적어도 99.5% 동일성, 또는 서열 식별 번호: 4의 98%에 걸쳐 적어도 99.5% 동일성, 또는 서열 식별 번호: 4의 100%에 걸쳐 서열 식별 번호: 4에 적어도 99.5% 서열 동일성을 가진 염색체를 가질 수 있다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 16S rRNA 서열을 측접하는 영역에서 서열 식별 번호: 4에 서열 동일성을 가진 염색체를 갖는다. 일부 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4에서 16S rRNA 서열의 직접 업스트림 및/또는 다운스트림으로 0.5kb 서열에 적어도 95% (예를 들면 적어도 96%, 97%, 98%, 99%, 99.5% 또는 100%) 서열 동일성을 가진 염색체를 갖는다. 일부 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4에서 16S rRNA 서열의 직접 업스트림 및/또는 다운스트림으로 1kb 서열에 적어도 95% (예를 들면 적어도 96%, 97%, 98%, 99%, 99.5% 또는 100%) 서열 동일성을 가진 염색체를 갖는다. 일부 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4에서 16S rRNA 서열의 직접 업스트림 및/또는 다운스트림으로 1.5kb 서열에 적어도 95% (예를 들면 적어도 96%, 97%, 98%, 99%, 99.5% 또는 100%) 서열 동일성을 가진 염색체를 갖는다. 일부 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 서열 식별 번호: 4에서 16S rRNA 서열의 직접 업스트림 및/또는 다운스트림으로 2kb 서열에 적어도 95% (예를 들면 적어도 96%, 97%, 98%, 99%, 99.5% 또는 100%) 서열 동일성을 가진 염색체를 갖는다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는, 예를 들어 상기에 기재된 바와 같이, 서열 식별 번호: 4에 서열 동일성을 가진 염색체, 및 예를 들어 상기에 기재된 바와 같이, 임의의 서열 식별 번호: 1, 2 또는 3에 서열 동일성을 가진 16S rRNA 서열, 바람직하게는 하기에 적어도 99% 동일한 16s rRNA 서열을 가진 염색체를 갖는다: 서열 식별 번호: 3, 더 바람직하게는 서열 식별 번호: 3의 16S rRNA 서열을 포함한다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는, 예를 들어 상기에 기재된 바와 같이, 서열 식별 번호: 4에 서열 동일성을 갖는 염색체를 갖고, IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적이다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는, 예를 들어 상기에 기재된 바와 같이, 서열 식별 번호: 4에 서열 동일성을 갖는 염색체를 갖고, 하기에 서열 동일성을 가진 16S rRNA 서열을 갖고: 임의의 서열 식별 번호: 1, 2 또는 3, 예를 들어 상기에 기재된 바와 같이, 그리고 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적이다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 하기로 표시되는 16s rRNA 서열에 적어도 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖고: 서열 식별 번호: 3 (예를 들어, 서열 식별 번호: 3의 16S rRNA 서열을 포함한다) 및 서열 식별 번호: 4의 적어도 40%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성을 가진 염색체, 그리고 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적이다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 하기로 표시되는 16s rRNA 서열에 적어도 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖고: 서열 식별 번호: 3 (예를 들어, 서열 식별 번호: 3의 16S rRNA 서열을 포함한다) 및 서열 식별 번호: 4의 적어도 90%에 걸쳐 서열 식별 번호: 4에 적어도 95% 서열 동일성을 가진 염색체, 그리고 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적이다.
특정 구현예에서, 본 발명에 사용하기 위한 박테리아 균주는 에리시펠라토클로스트리디움 라모숨이고 하기로 표시되는 16s rRNA 서열에 적어도 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖고: 서열 식별 번호: 3 (예를 들어, 서열 식별 번호: 3의 16S rRNA 서열을 포함한다) 및 서열 식별 번호: 4의 적어도 98%에 걸쳐 (예를 들면 적어도 99% 또는 적어도 99.5%에 걸쳐) 서열 식별 번호: 4에 적어도 98% 서열 동일성 (예를 들면 적어도 99% 또는 적어도 99.5% 서열 동일성)을 가진 염색체, 그리고 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 또는 예방에 효과적이다.
바람직한 구현예에서, 본 발명의 조성물 중의 박테리아 균주는 생장 가능하고 장을 부분적으로 또는 전체적으로 콜로니화할 수 있다.
치료 용도
실시예에서 입증된 바와 같이, 본 발명의 박테리아 조성물은 Th17 염증 반응을 감소시키는 데 효과적이다. 특히, 본 발명의 조성물로 치료는 IL-17 및 Th17 경로에 의해 매개된 병태의 동물 모델에서 임상 개선을 달성하고 IL-17A 수준 및 다른 Th17 경로 사이토카인에서 감소를 달성할 수 있다. 따라서, 본 발명의 조성물은 염증성 및 자가면역 질환, 특히 IL-17에 의해 매개되는 질병 또는 병태를 치료 또는 예방하는 데 유용할 수 있다. 특히, 본 발명의 조성물은 IL-17 염증 반응의 상승을 감소 또는 방지하는 데 유용할 수 있다.
Th17 세포는 예를 들어 IL-17A, IL17-F, IL-21 및 IL22를 생성하는 T 헬퍼 세포의 하위 집합이다. Th17 세포 분화 및 IL-17 발현은 IL-23에 의해 유도될 수 있다. 이들 사이토카인 및 다른 것들은 Th17 경로의 중요한 부분을 형성하는데, 이는(예를 들어 [21, 22, 23, 24, 25, 26]에서 기재된 바와 같이) 다수의 염증 및 자가면역 질환에 기여하고 근원이 되는 잘 확립된 염증 신호 수송 경로이다. Th17 경로가 활성화되는 질병은 Th17 경로-매개 질병이다. Th17 경로-매개 질병은 Th17 세포의 분화를 줄이거나 Th17 세포의 활성을 감소시키거나 Th17 경로 사이토카인의 수준을 감소시키는 등 Th17 경로를 억제함으로써 개선 또는 완화될 수 있다. Th17 경로에 의해 매개되는 질병은 IL-17A, IL-17F, IL-21, IL-22, IL-26, IL-9와 같은 Th17 세포에 의해 생성되는 사이토카인의 증가된 수준을 특징으로 할 수 있다([27] 에서 검토). Th17 경로에 의해 매개되는 질병은 Stat3 또는 IL-23R과 같은 Th-17-관련 유전자의 발현 증가를 특징으로 할 수 있다. Th17 경로에 의해 매개되는 질병은 증가된 Th17 세포 수준과 관련이 있을 수 있다.
IL-17은 염증 및 자가면역 질환 및 병태의 발병 기전에 기여하는 전염증성 사이토카인이다. 본원에 사용된 IL-17은 IL-17A, IL-17B, IL-17C, IL-17D, IL-17E 및 IL-17F를 포함하는 IL-17 계열의 임의의 구성원을 지칭할 수 있다. IL-17-매개 질병 및 조건은 IL-17의 높은 발현 및/또는 질병 또는 병태에 의해 영향을 받는 조직에서의 IL-17-양성 세포의 축적 또는 존재를 특징으로 한다. 유사하게, IL-17-매개 질병 및 병태는 높은 IL-17 수준 또는 IL-17 수준의 증가에 의해 악화되고 낮은 IL-17 수준 또는 IL-17 수준의 감소에 의해 완화되는 질병 및 병태이다. IL-17 염증 반응은 국소 또는 전신성일 수 있다.
IL-17 또는 Th17 경로에 의해 매개될 수 있는 질환 및 병태의 예는 하기를 포함한다: 포도막염; 암, 예컨대 유방암, 폐암, 간암, 결장암, 또는 난소암; 다발성 경화증; 관절염, 예컨대 류마티스성 관절염, 골관절염, 건선성 관절염, 또는 유년성 특발성 관절염; 시신경척수염 (데빅병); 강직 척추염; 척추관절염; 건선; 전신 홍반성 낭창; 염증성 장 질환, 예컨대 크론병 또는 궤양성 대장염; 소아지방변증; 천식, 예컨대 알러지성 천식 또는 호중구성 천식; 만성 폐쇄성 폐 질환 (COPD); 공막염; 혈관염; 베체트병; 죽상경화증; 아토피 피부염; 폐공기증; 치주염; 알러지성 비염; 및 동종이식편 거부반응. 바람직한 구현예에서, 본 발명의 조성물은 이들 병태 또는 질병 중 하나 이상을 치료 또는 예방하는 데 사용된다. 추가의 바람직한 구현예에서, 이들 병태 또는 질병은 IL-17 또는 Th17 경로에 의해 매개된다.
일부 구현예에서, 질환 또는 병태의 발병은 장에 영향을 준다. 일부 구현예에서, 질환 또는 병태의 발병은 장에 영향을 주지 않는다. 일부 구현예에서, 질환 또는 병태의 발병은 장에서 국재화되지 않는다. 일부 구현예에서, 치료 또는 예방은 장이 아닌 부위에서 발생한다. 일부 구현예에서, 치료 또는 예방은 장에서 그리고 또한 장이 아닌 부위에서 발생한다. 특정 구현예에서, 질환 또는 병태는 전신성이다.
특정 구현예에서, 본 발명의 조성물은 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태의 치료 또는 예방에서 IL-17 생산을 감소시키거나 Th17 세포 분화를 감소시키는 방법에 사용하기 위한 것이다. 특정 구현예서, 본 발명의 조성물은 염증성 또는 자가면역 질환의 치료 또는 예방에 사용하기 위한 것이며, 상기 치료 또는 예방은 Th17 염증 반응의 상승을 감소 또는 방지함으로써 달성된다. 특정 구현예에서, 본 발명의 조성물은 염증성 또는 자가면역 질환을 갖는 환자를 치료하는 데 사용하기 위한 것으로, 환자는 IL-17 수준의 상승 또는 Th17 세포의 증가 또는 Th17 염증 반응을 나타낸다. 특정 구현예에서, 환자는 만성 염증성 또는 자가면역 질환 또는 병태로 진단되었을 수 있거나, 본 발명의 조성물은 염증성 또는 자가면역 질환 또는 만성 염증성 또는 자가면역 질환 또는 병태로 진행되는 병태를 예방하는 데 사용하기 위한 것일 수 있다. 특정 구현예에서, 질병 또는 병태는 TNF-α 억제제에 의한 치료에 반응하지 않을 수 있다. 본 발명의 이러한 용도는 이전 단락에 열거된 특정 질병 또는 병태 중 어느 하나에 적용될 수 있다.
IL-17 및 Th17 경로는 종종 만성 염증성 및 자가면역 질환과 관련되기 때문에, 본 발명의 조성물은 상기 열거된 만성 질환 또는 병태를 치료 또는 예방하는 데 특히 유용할 수 있다. 특정 구현예에서, 조성물은 만성 질환을 갖는 환자에게 사용하기 위한 것이다. 특정 구현예에서, 조성물은 만성 질환의 발병을 예방하는 데 사용하기 위한 것이다.
본 발명의 조성물은 IL-17 또는 Th17 경로에 의해 매개되는 질병 및 병태를 치료하고 Th17 염증 반응을 다루는 데 유용할 수 있기 때문에, 본 발명의 조성물은 만성 질환의 치료 또는 예방, 다른 치료법에 반응하지 않은 환자의 질병의 치료 또는 예방(예를 들어 TNF-α 억제제에 의한 치료) 및/또는 조직 손상 및 및 IL-17 및 Th17 세포와 관련된 증상의 치료 또는 예방에 특히 유용할 수 있다. 예를 들어, IL-17은 연골 및 뼈 조직에서 기질 파괴를 활성화시키는 것으로 알려져 있으며, IL-17은 연골 세포 및 골아 세포에서의 기질 생성에 억제 효과를 가지기 때문에, 본 발명의 조성물은 골 침식 또는 연골 손상을 치료 또는 예방하는 데 유용할 수 있다.
특정 구현예에서, 본 발명의 조성물로 처리하면 IL-17 수준, 특히 IL-17A 수준의 감소를 제공하거나 상승을 방지한다. 특정 구현예에서, 본 발명의 조성물로 치료는 TNFα, IFN-γ 또는 IL-6 수준에서 감소를 제공하거나 상승을 방지한다. 이러한 사이토카인의 증가된 수준의 감소 또는 예방은 염증성 및 자가면역 질환 및 병태, 특히 IL-17 또는 Th17 경로에 의해 매개되는 것들을 치료 또는 예방하는 데 유용할 수 있다.
포도막염
바람직한 구현예에서, 본 발명의 조성물은 포도막염의 치료 또는 예방에 사용하기 위한 것이다. 그 예는 본 발명의 조성물이 포도막염의 동물 모델에서 질환 발병률 및 질환 중증도의 감소를 달성하고 그래서 이들이 포도막염의 치료 또는 예방에서 유용할 수 있다는 것을 입증한다. 포도막염은 포도막의 염증으로 망막 조직 파괴를 일으킬 수 있다. 이것은 다른 해부학적 형태(전방, 중간, 후방 또는 확산)로 나타날 수 있으며, 전립선자가면역 장애를 포함하여 다르지만 관련된 원인으로 인해 발생할 수 있다. IL-17 및 Th17 경로는 포도막염에 집중적으로 관여되고, 그래서 포도막염 치료에 대한 본 발명의 조성물의 효능은 본 발명의 조성물이 IL-17 또는 Th17 경로에 의해 매개된 질환 및 병태의 치료 및 예방에 특히 효과적일 수 있다는 것을 나타낸다. 참고문헌 [28, 29, 30, 31, 32, 33, 34, 35]는 하기를 기재한다: 포도막염 환자에서 인터류킨-17A의 상승된 혈청 수준, 범포도막염과 IL17A 유전적 변이체의 특이적인 회합, 실험적 자가면역 포도막염의 발병에서 Th17-관련된 사이토카인의 역할, 단상 실험적 자가면역 포도막염 동안 Th17 세포와 조절 T 세포 사이 불균형, 포도막염 및 활성 아다만티아데스-베체트 및 포크트-고야나기-하라다 (VKH) 질환을 가진 환자에서 IL-17A의 상향조절, 세쿠키누맙 (항-IL-17A 항체)으로 비-감염성 포도막염의 치료, 및 포도막 눈에서의 Th17.
특정 구현예에서, 포도막염은 후방 포도막염이다. 후방 포도막염은 망막 및 맥락막의 염증으로 주로 나타나고 그 예는 본 발명의 조성물이 망막 염증 및 손상 감소에 효과적인 것을 입증한다.
특정 구현예에서, 본 발명의 조성물로 치료하면 망막 손상이 감소한다. 특정 구현예에서, 본 발명의 조성물은 포도막염의 치료에서 망막 손상을 감소시키거나 예방하는 데 사용하기 위한 것이다. 특정 구현예에서, 조성물은 망막 손상의 위험이 있는 중증 포도막염 환자를 치료하는 데 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 치료하면 시신경 유두 염증이 감소된다. 특정 구현예에서, 본 발명의 조성물은 시신경 유두 염증을 감소 또는 예방하는 데 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 치료하면 염증 세포에 의한 망막 조직 침윤이 감소된다. 특정 구현예에서, 본 발명의 조성물은 염증 세포에 의한 망막 조직 침윤의 감소에 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 치료하면 시력이 유지되거나 개선된다. 특정 구현예에서, 본 발명의 조성물은 시력 유지 또는 개선에 사용하기 위한 것이다.
특정 구현예에서, 조성물은 베체트 병, 크론 병, 푸치 이성변색 홍지모양체염, 다발 혈관염을 동반한 육아종증, HLA-B27 관련 포도막염, 청소년 특발성 관절염, 유육종증, 척추 관절염, 교감 신경 안검, 세뇨관 간질 신염 및 포도막염 증후군 또는 보그-고야나기-하라다 증후군과 같은 비-감염성 또는 자가면역 질환과 관련된 포도막염의 치료 또는 예방에 사용하기 위한 것이다. IL-17A는 예를 들어 베체트 및 보그-고야나기-하라다 질병에 관여하는 것으로 나타났다.
포도막염의 치료 또는 예방은 예를 들어 증상의 중증도의 완화 또는 재발 방지를 의미할 수 있다.
암
바람직한 구현예에서, 본 발명의 조성물은 암의 치료 또는 예방에 사용하기 위한 것이다. IL-17 및 Th17 경로는 암 발병 및 진행에서 중추적 역할을 갖고, 그래서 본 발명의 조성물은 암 치료 또는 예방에 유용할 수 있다.
암에서 IL-17 및 Th17 세포의 역할이 완전히 이해되지 않아도, IL-17 및 Th17 세포의 수많은 전-종양 효과는 공지되어 있다. 예를 들어, Th17 세포 및 IL-17은 혈관신생을 촉진시킬 수 있고, 종양 세포의 증식 및 생존을 증가시킬 수 있고 종양-촉진 전사 인자를 활성화시킬 수 있다 [36, 37, 38].
특정 구현예에서, 본 발명의 조성물을 사용한 치료는 종양 크기의 감소 또는 종양 성장의 감소를 초래한다. 특정 구현예에서, 본 발명의 조성물은 종양 크기를 감소시키거나 종양 성장을 감소시키는 데 사용하기 위한 것이다. 본 발명의 조성물은 종양 크기 또는 성장 감소에 효과적일 수 있다. .특정 구현예에서, 본 발명의 조성물은 고형 종양 환자에게 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물은 암 치료에서 혈관신생을 감소 또는 예방하는 데 사용하기 위한 것이다. IL-17 및 Th17 세포는 혈관신생에 중추적 역할을 한다. 특정 구현예에서, 본 발명의 조성물은 전이를 예방하는 데 사용하기 위한 것이다.
특정 구현예에서, 본 발명의 조성물은 유방암의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 유방암 치료에 효과적일 수 있고, IL-17 및 Th17 세포는 유방암에서 중요한 역할을 한다[39]. 특정 구현예에서, 본 발명의 조성물은 종양 크기 감소, 종양 성장 감소, 또는 유방암의 치료에서 혈관신생 감소에서 사용하기 위한 것이다. 바람직한 구현예에서, 암은 유방암이다. 바람직한 구현예에서, 암은 IV 기 유방암이다.
특정 구현예에서, 본 발명의 조성물은 폐암의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 폐암 치료에 효과적일 수 있고, IL-17 및 Th17 세포는 폐암에서 중요한 역할을 한다[40]. 특정 구현예에서, 본 발명의 조성물은 종양 크기 감소, 종양 성장 감소, 또는 폐암의 치료에서 혈관신생 감소에서 사용하기 위한 것이다. 바람직한 구현예에서, 암은 폐암이다.
특정 구현예에서, 본 발명의 조성물은 간암의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 간암 치료에 효과적일 수 있고, IL-17 및 Th17 세포는 간암에서 중요한 역할을 한다[41]. 특정 구현예에서, 본 발명의 조성물은 종양 크기 감소, 종양 성장 감소, 또는 간암의 치료에서 혈관신생 감소에서 사용하기 위한 것이다. 바람직한 구현예에서, 암은 간암(간세포 암종)이다.
특정 구현예에서, 본 발명의 조성물은 암종의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 암종 치료에 특히 효과적일 수 있다. 특정 구현예에서, 본 발명의 조성물은 비-면역원성 암을 치료 또는 예방하는 데 사용하기 위한 것이다. 본 발명의 조성물은 비-면역원성 암 치료에 효과적일 수 있다.
추가 구현예에서, 본 발명의 조성물은 급성 림프아구성 백혈병(ALL), 급성 골수 백혈병, 부신피질 암종, 기저-세포 암종, 담도암, 방광암, 골 종양, 골육종/악성 섬유질 조직구종, 뇌간 신경아교종, 뇌종양, 소뇌 별아교세포종, 뇌 별아교세포종/악성 신경아교종, 뇌실막세포종, 수모세포종, 천막상 원시 신경외배엽성 종양, 유방암, 기관지 선종/카르시노이드, 버킷 림프종, 유암종, 자궁경부암, 만성 림프구성 백혈병, 만성 골수성 백혈병, 만성 골수증식성 장애, 결장암, 피부 T-세포 림프종, 자궁내막 암, 뇌실막세포종, 식도암, 유잉 육종, 안구내 흑색종, 망막모세포종, 담낭암, 위암, 위장 유암종, 위장 기질 종양(GIST), 생식세포 종양, 신경아교종, 소아기 시각적 경로 및 시상하부, 호지킨 림프종, 흑색종, 소도세포 암종, 카포시 육종, 신장 세포 암, 후두 암, 백혈병, 림프종, 중피종, 신경교세포종, 비-호지킨 림프종, 구강인두 암, 골육종, 난소암, 췌장암, 부갑상선암, 인두 암, 뇌하수체 샘종, 형질 세포 신조직형성, 전립선암, 신장 세포 암종, 망막모세포종, 육종, 고환암, 갑상선암, 또는 자궁암을 치료 또는 예방하는 데 사용하기 위한 것이다.
본 발명의 조성물은 추가의 치료제와 조합하여 사용될 때 특히 효과적일 수 있다. 본 발명의 조성물의 면역-조절 효과는 보다 직접적인 항암제와 조합될 때 효과적일 수 있다. 따라서, 특정 구현예에서, 본 발명은 속 에리시펠라토클로스트리디움의 박테리아 균주 및 항암제를 포함하는 조성물을 제공한다. 바람직한 구현예에서, 항암제는 면역 체크포인트 억제제, 표적 항체 면역요법, CAR-T 세포 요법, 온콜리틱 바이러스 또는 세포증식 억제제이다. 바람직한 구현예에서, 상기 조성물은 하기로 이루어진 군으로부터 선택된 항암제를 포함한다:Yervoy (이필리무맙, BMS); Keytruda (펨브롤리주맙, Merck); Opdivo (니볼루맙, BMS); MEDI4736(AZ/MedImmune); MPDL3280A(Roche/Genentech); 트레멜리무맙(AZ/MedImmune); CT-011(피딜리주맙, CureTech); BMS-986015(리릴루맙, BMS); MEDI0680(AZ/MedImmune); MSB-0010718C(Merck); PF-05082566(Pfizer); MEDI6469(AZ/MedImmune); BMS-986016(BMS); BMS-663513(우렐루맙, BMS); IMP321(Prima Biomed); LAG525(Novartis); ARGX-110(arGEN-X); PF-05082466(Pfizer); CDX-1127(바릴루맙; CellDex Therapeutics); TRX-518(GITR Inc.);MK-4166 (Merck); JTX-2011 (Jounce Therapeutics); ARGX-115 (arGEN-X); NLG-9189 (인독시모드, NewLink Genetics); INCB024360 (Incyte); IPH2201 (Innate Immotherapeutics/AZ); NLG-919 (NewLink Genetics); 항-VISTA (JnJ); Epacadostat (INCB24360, Incyte); F001287 (Flexus/BMS); CP 870893 (University of Pennsylvania); MGA271 (Macrogenix); 에막투주맙 (Roche/Genentech); 갈루니세르팁 (Eli Lilly); 울로쿠플루맙 (BMS); BKT140/BL8040 (Biokine Therapeutics); 바비툭시맙 (Peregrine Pharmaceuticals); CC 90002 (Celgene); 852A (Pfizer); VTX-2337 (VentiRx Pharmaceuticals); IMO-2055 (Hybridon, Idera Pharmaceuticals); LY2157299 (Eli Lilly); EW-7197 (Ewha Women's University, Korea); 베무라페닙 (Plexxikon); 다브라페닙 (Genentech/GSK); BMS-777607 (BMS); BLZ945 (Memorial Sloan-Kettering Cancer Centre); Unituxin (디누툭시맙, United Therapeutics Corporation); Blincyto (블리나투모맙, Amgen); Cyramza (라무시루맙, Eli Lilly); Gazyva (오비누투주맙, Roche/Biogen); Kadcyla (아도-트라스투주맙 엠탄신, Roche/Genentech); Perjeta (페르투주맙, Roche/Genentech); Adcetris (브렌툭시맙 베도틴, Takeda/Millennium); Arzerra (오파투무맙, GSK); Vectibix (파니투무맙, Amgen); Avastin (베바시주맙, Roche/Genentech); Erbitux (세툭시맙, BMS/Merck); Bexxar (토시투모맙-I131, GSK); Zevalin (이브리투모맙 티욱세탄, Biogen); Campath (알렘투주맙, Bayer); Mylotarg (젬투주맙 오조가마이신, Pfizer); Herceptin (트라스투주맙, Roche/Genentech); Rituxan (리툭시맙, Genentech/Biogen); 볼록식시맙 (Abbvie); 에나바투주맙 (Abbvie); ABT-414 (Abbvie); 엘로투주맙 (Abbvie/BMS); ALX-0141 (Ablynx); 오자랄리주맙 (Ablynx); 악티맙-C (Actinium); 악티맙-P (Actinium); 밀라투주맙-독스 (Actinium); Emab-SN-38 (Actinium); 납투몬맙 에스타페나톡스 (Active Biotech); AFM13 (Affimed); AFM11 (Affimed); AGS-16C3F (Agensys); AGS-16M8F (Agensys); AGS-22ME (Agensys); AGS-15ME (Agensys); GS-67E (Agensys); ALXN6000 (samalizumab, Alexion); ALT-836 (Altor Bioscience); ALT-801 (Altor Bioscience); ALT-803 (Altor Bioscience); AMG780 (Amgen); AMG 228 (Amgen); AMG820 (Amgen); AMG172 (Amgen); AMG595 (Amgen); AMG110 (Amgen); AMG232 (아데카투무맙, Amgen); AMG211 (Amgen/MedImmune); BAY20-10112 (Amgen/Bayer); 릴로투무맙 (Amgen); 데노수맙 (Amgen); AMP-514 (Amgen); MEDI575 (AZ/MedImmune); MEDI3617 (AZ/MedImmune); MEDI6383 (AZ/MedImmune); MEDI551 (AZ/MedImmune); 목세투무맙 파수도톡스 (AZ/MedImmune); MEDI565 (AZ/MedImmune); MEDI0639 (AZ/MedImmune); MEDI0680 (AZ/MedImmune); MEDI562 (AZ/MedImmune); AV-380 (AVEO); AV203 (AVEO); AV299 (AVEO); BAY79-4620 (Bayer); 아네투맙 라브탄신 (Bayer); 반틱투맙 (Bayer); BAY94-9343 (Bayer); 시브로투주맙 (Boehringer Ingleheim); BI-836845 (Boehringer Ingleheim); B-701 (BioClin); BIIB015 (Biogen); 오비누투주맙 (Biogen/Genentech); BI-505 (Bioinvent); BI-1206 (Bioinvent); TB-403 (Bioinvent); BT-062 (Biotest) BIL-010t (Biosceptre); MDX-1203 (BMS); MDX-1204 (BMS); 네시투무맙 (BMS); CAN-4 (Cantargia AB); CDX-011 (Celldex); CDX1401 (Celldex); CDX301 (Celldex); U3-1565 (Daiichi Sankyo); 파트리투맙 (Daiichi Sankyo); 티가투주맙 (Daiichi Sankyo); 니모투주맙 (Daiichi Sankyo); DS-8895 (Daiichi Sankyo); DS-8873 (Daiichi Sankyo); DS-5573 (Daiichi Sankyo); MORab-004 (Eisai); MORab-009 (Eisai); MORab-003 (Eisai); MORab-066 (Eisai); LY3012207 (Eli Lilly); LY2875358 (Eli Lilly); LY2812176 (Eli Lilly); LY3012217(Eli Lilly); LY2495655 (Eli Lilly); LY3012212 (Eli Lilly); LY3012211 (Eli Lilly); LY3009806 (Eli Lilly); 식수투무맙 (Eli Lilly); 플란보투맙 (Eli Lilly); IMC-TR1 (Eli Lilly); 라무시루맙 (Eli Lilly); 타발루맙 (Eli Lilly); 자놀리무맙 (Emergent Biosolution); FG-3019 (FibroGen); FPA008 (Five Prime Therapeutics); FP-1039 (Five Prime Therapeutics); FPA144 (Five Prime Therapeutics); 카투막소맙 (Fresenius Biotech); IMAB362 (Ganymed); IMAB027 (Ganymed); HuMax-CD74 (Genmab); HuMax-TFADC (Genmab); GS-5745 (Gilead); GS-6624 (Gilead); OMP-21M18 (demcizumab, GSK); 마파투무맙 (GSK); IMGN289 (ImmunoGen); IMGN901 (ImmunoGen); IMGN853 (ImmunoGen); IMGN529 (ImmunoGen); IMMU-130 (Immunomedics); 밀라투주맙-독스 (Immunomedics); IMMU-115 (Immunomedics); IMMU-132 (Immunomedics); IMMU-106 (Immunomedics); IMMU-102 (Immunomedics); 에프라투주맙 (Immunomedics); 클리바투주맙 (Immunomedics); IPH41 (Innate Immunotherapeutics); 다라투무맙 (Janssen/Genmab); CNTO-95 (인테투무맙, Janssen); CNTO-328 (실툭시맙, Janssen); KB004 (KaloBios); 모가물리주맙 (Kyowa Hakko Kirrin); KW-2871 (에크로멕시맙, Life Sciennce); 소네프시주맙 (Lpath); 마르게툭시맙 (Macrogenics); 에노블리투주맙 (Macrogenics); MGD006 (Macrogenics); MGF007 (Macrogenics); MK-0646 (달로투주맙, Merck); MK-3475 (Merck); Sym004 (Symphogen/Merck Serono); DI17E6 (Merck Serono); MOR208 (Morphosys); MOR202 (Morphosys); Xmab5574 (Morphosys); BPC-1C (엔시툭시맙, Precision Biologics); TAS266 (Novartis); LFA102 (Novartis); BHQ880 (Novartis/Morphosys); QGE031 (Novartis); HCD122 (루카투무맙, Novartis); LJM716 (Novartis); AT355 (Novartis); OMP-21M18 (뎀시주맙, OncoMed); OMP52M51 (Oncomed/GSK); OMP-59R5 (Oncomed/GSK); 반틱투맙 (Oncomed/Bayer); CMC-544 (이노투주맙 오조가마이신, Pfizer); PF-03446962 (Pfizer); PF-04856884 (Pfizer); PSMA-ADC (Progenics); REGN1400 (Regeneron); REGN910 (네스바쿠맙, Regeneron/Sanofi); REGN421 (에노티쿠맙, Regeneron/Sanofi); RG7221, RG7356, RG7155, RG7444, RG7116, RG7458, RG7598, RG7599, RG7600, RG7636, RG7450, RG7593, RG7596, DCDS3410A, RG7414 (파르사투주맙), RG7160 (임가투주맙), RG7159 (오빈투주맙), RG7686, RG3638 (오나투주맙), RG7597 (Roche/Genentech); SAR307746 (Sanofi); SAR566658 (Sanofi); SAR650984 (Sanofi); SAR153192 (Sanofi); SAR3419 (Sanofi); SAR256212 (Sanofi), SGN-LIV1A (린투주맙, Seattle Genetics); SGN-CD33A (Seattle Genetics); SGN-75 (보르세투주맙 마포도틴, Seattle Genetics); SGN-19A (Seattle Genetics) SGN-CD70A (Seattle Genetics); SEA-CD40 (Seattle Genetics); 이브리투모맙 티욱세탄 (Spectrum); MLN0264 (Takeda); 가니투맙 (Takeda/Amgen); CEP-37250 (Teva); TB-403 (Thrombogenic); VB4-845 (Viventia); Xmab2512 (Xencor); Xmab5574 (Xencor); 니모투주맙 (YM Biosciences); Carlumab (Janssen); NY-ESO TCR (Adaptimmune); MAGE-A-10 TCR (Adaptimmune); CTL019 (Novartis); JCAR015 (Juno Therapeutics); KTE-C19 CAR (Kite Pharma); UCART19 (Cellectis); BPX-401 (Bellicum Pharmaceuticals); BPX-601 (Bellicum Pharmaceuticals); ATTCK20 (Unum Therapeutics); CAR-NKG2D (Celyad); Onyx-015 (Onyx Pharmaceuticals); H101 (Shanghai Sunwaybio); DNX-2401 (DNAtrix); VCN-01 (VCN Biosciences); Colo-Ad1 (PsiOxus Therapeutics); ProstAtak (Advantagene); Oncos-102 (Oncos Therapeutics); CG0070 (Cold Genesys); Pexa-vac (JX-594, Jennerex Biotherapeutics); GL-ONC1 (Genelux); T-VEC (Amgen); G207 (Medigene); HF10 (Takara Bio); SEPREHVIR (HSV1716, Virttu Biologics); OrienX010 (OrienGene Biotechnology); Reolysin (Oncolytics Biotech); SVV-001 (Neotropix); Cacatak (CVA21, Viralytics); Alimta (Eli Lilly), 시스플라틴, 옥살리플라틴, 이리노테칸, 폴린산, 메토트렉세이트, 사이클로포스파마이드, 5-플루오로우라실, Zykadia (Novartis), Tafinlar (GSK), Xalkori (Pfizer), Iressa (AZ), Gilotrif (Boehringer Ingelheim), Tarceva (Astellas Pharma), Halaven (Eisai Pharma), Veliparib (Abbvie), AZD9291 (AZ), Alectinib (Chugai), LDK378 (Novartis), Genetespib (Synta Pharma), Tergenpumatucel-L (NewLink Genetics), GV1001 (Kael-GemVax), Tivantinib (ArQule); Cytoxan (BMS); Oncovin (Eli Lilly); Adriamycin (Pfizer); Gemzar (Eli Lilly); Xeloda (Roche); Ixempra (BMS); Abraxane (Celgene); Trelstar (Debiopharm); Taxotere (Sanofi); Nexavar (Bayer); IMMU-132 (Immunomedics); E7449 (Eisai); Thermodox (Celsion); Cometriq (Exellxis); Lonsurf (Taiho Pharmaceuticals); Camptosar (Pfizer); UFT (Taiho Pharmaceuticals); 및 TS-1 (Taiho Pharmaceuticals).
일부 구현예에서, 하나 이상의 에리시펠라토클로스트리디움 박테리아 균주는 본 발명의 조성물에서 단지 치료적으로 활성제(들)이다. 일부 구현예에서, 조성물에서 박테리아 균주(들)은 본 발명의 조성물에서 단지 치료적으로 활성제(들)이다.
천식
바람직한 구현예에서, 본 발명의 조성물은 천식의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 집먼지 진드기 추출물로 감작화 및 공격 이후 기도 내부에 호중구 및/또는 호산구의 동원에서 감소를 달성할 수 있고 그래서 이들은 천식의 치료 또는 예방에서 유용할 수 있다. 천식은 염증과 기도의 제한을 특징으로 하는 만성 질환이다. 천식에서의 염증은 IL-17 및/또는 Th17 세포에 의해 매개될 수 있고, 따라서 본 발명의 조성물은 천식의 예방 또는 치료에 특히 효과적일 수 있다. 천식의 염증은 호산구 및/또는 호중구에 의해 매개될 수 있다.
특정 구현예에서, 천식은 호산구성 또는 알레르기성 천식이다. 호산구성 및 알레르기성 천식은 말초 혈액 및 기도 분비의 호산구 수가 증가하고 병리학적으로 기저막 부위가 두꺼워지고 약리학적으로 코르티코스테로이드 반응성과 관련이 있다 [42]. 호산구 모집 또는 활성화를 감소시키거나 억제하는 조성물은 호산구성 및 알레르기성 천식을 치료 또는 예방하는 데 유용할 수 있다.
추가의 구현예에서, 본 발명의 조성물은 호중구성 천식(또는 비-호산구성 천식)의 치료 또는 예방에 사용하기 위한 것이다. 호중구 수가 많으면 코티코스테로이드 치료에 민감하지 않은 심각한 천식이 동반된다. 호중구 모집 또는 활성화를 감소시키거나 억제하는 조성물은 호중구성 천식을 치료 또는 예방하는 데 유용할 수 있다.
호산구성 및 호중구성 천식은 상호 배타적인 조건이 아니며 호산구와 호중구 반응을 다루는 치료법은 일반적으로 천식 치료에 유용할 수 있다.
증가된 IL-17 수준 및 Th17 경로의 활성화는 심한 천식과 관련되기 때문에, 본 발명의 조성물은 중증 천식의 발병을 예방하거나 중증 천식 치료에 유용할 수 있다.
특정 구현예에서, 본 발명의 조성물은 천식의 치료 또는 예방에서 호산구성 염증 반응을 감소시키는 방법에 사용하거나, 또는 천식의 치료 또는 예방에서 호중구성 염증 반응을 감소시키는 방법에 사용하기 위한 것이다. 위에서 언급했듯이, 천식의 호산구 수치가 높으면 병리학적으로 기저막 부위가 두꺼워지므로 천식 치료 또는 예방에서 호산구성 염증 반응을 감소시키는 것이 이 질병의 특징을 구체적으로 다룰 수 있다. 또한 상승된 호중구는 호산구 증가와 함께 또는 부재시에 중증 천식 및 만성 기도 협착과 관련이 있다. 따라서 호중구성 염증 반응을 감소시키는 것은 중증 천식을 치료할 때 특히 유용할 수 있다.
특정 구현예에서, 조성물은 알레르기성 천식에서의 기관지주위 침윤을 감소시키거나, 알레르기성 천식의 치료에서 기관지주위 침윤을 감소시키는 데 사용하기 위한 것이다. 특정 구현예에서, 조성물은 호중구성 천식에서 기관지주위 및/또는 혈관주위 침윤을 감소시키거나, 알레르기성 호중구성 천식의 치료에서 기관지주위 및/또는 혈관주위 침윤을 감소시키는 데 사용하기 위한 것이다.
특정 구현예에서, 본 발명의 조성물로 치료는 TNFα 수준에서 감소를 제공하거나 상승을 방지한다.
특정 구현예에서, 본 발명의 조성물은 호산구성 및/또는 호중구성 염증 반응의 감소를 초래하는 천식 치료 방법에 사용하기 위한 것이다. 특정 구현예에서, 치료될 환자는 예를 들어 혈액 샘플링 또는 객담 분석을 통해 확인된 바와 같이, 상승된 호중구 또는 호산구 수치를 갖거나 이전에 확인된 것이다.
본 발명의 조성물은 신생아 또는 임산부에게 투여될 때 신생아에서 천식 발병을 예방하는 데 유용할 수 있다. 상기 조성물은 소아 천식의 발병을 예방하는 데 유용할 수 있다. 본 발명의 조성물은 성인-발병 천식을 치료 또는 예방하는 데 유용할 수 있다. 본 발명의 조성물은 천식을 관리하거나 경감시키는 데 유용할 수 있다. 본 발명의 조성물은 집먼지 진드기와 같은 알레르겐에 의해 악화되는 천식과 관련된 증상을 감소시키는 데 특히 유용할 수 있다.
천식의 치료 또는 예방은 예를 들어 증상의 중증도의 완화 또는 악화 빈도의 감소 또는 환자에게 문제가 되는 유발인자의 범위를 나타낼 수 있다.
관절염
바람직한 구현예에서, 본 발명의 조성물은 류마티스성 관절염(RA)의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 마우스 모델에서 RA의 임상 징후에서의 감소를 달성할 수 있고, 연골 및 골 손상을 감소시킬 수 있고, IL-17 염증 반응을 감소시킬 수 있고, 그래서 이들은 RA의 치료 또는 예방에서 유용할 수 있다. RA는 주로 관절에 영향을 미치는 전신성 염증 질환이다. RA는 관절의 팽윤, 활막의 과형성 및 연골과 뼈의 파괴를 가져오는 염증 반응과 관련이 있다. 예를 들어, IL-17은 연골 세포와 골아 세포에서의 매트릭스 생산을 억제하고 매트릭스 메탈로프로티나아제의 생산과 기능을 활성화시키고 RA 질병 활성은 IL-17 수준 및 Th17 세포수와 상호 관련되기 때문에 IL-17과 Th17 세포는 RA에서 중요한 역할을 할 수 있으며[43, 44], 따라서 본 발명의 조성물은 RA의 예방 또는 치료에 특히 효과적일 수 있다.
특정 구현예에서, 본 발명의 조성물은 RA의 치료 또는 예방에서 IL-17 수준을 낮추거나 IL-17 수준의 상승을 방지하는 데 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 처리하면 IL-17 수준, 특히 IL-17A 수준의 감소를 제공하거나 상승을 방지한다. 특정 구현예에서, 본 발명의 조성물을 사용한 치료는 IFN-γ 또는 IL-6 수준의 감소를 제공하거나 상승을 방지한다.
특정 구현예에서, 본 발명의 조성물로 치료하면 관절의 팽윤이 감소한다. 특정 구현예에서, 본 발명의 조성물은 관절이 부어 오른 환자 또는 관절이 부어질 위험이 있는 환자에게 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물은 RA에서 관절 팽윤을 감소시키는 방법에 사용하기 위한 것이다.
특정 구현예에서, 본 발명의 조성물로 치료하면 연골 손상 또는 골 손상이 감소된다. 특정 구현예에서, 본 발명의 조성물은 RA의 치료에서 연골 또는 골 손상을 감소 또는 예방하는 데 사용하기 위한 것이다. 특정 구현예에서, 조성물은 연골 또는 뼈 손상의 위험이 있는 중증의 RA 환자를 치료하는 데 사용하기 위한 것이다.
증가된 IL-17 수준과 Th17 세포수는 RA에서 연골과 뼈 파괴와 관련이 있다[43,44]. IL-17은 연골과 뼈 조직에서 기질 파괴를 활성화시키는 것으로 알려져 있으며 IL-17은 연골 세포와 골아 세포에서 기질 생산에 억제 효과가 있다. 따라서, 특정 구현예에서, 본 발명의 조성물은 RA의 치료에서 골 침식 또는 연골 손상을 예방하는 데 사용하기 위한 것이다. 특정 구현예에서, 조성물은 골 침식 또는 연골 손상을 나타내는 환자 또는 골 침식 또는 연골 손상의 위험이 있는 것으로 확인된 환자를 치료하는 데 사용하기 위한 것이다.
TNF-α는 또한 RA와 연관되어 있지만 TNF-α는 질병의 후기 단계의 발병 기전에 관여하지 않는다. 대조적으로, IL-17은 만성 질환의 모든 단계에서 역할을 한다[45]. 따라서, 특정 구현예에서, 본 발명의 조성물은 만성 RA 또는 연골의 관절 파괴 및 손실을 포함하는 질병과 같은 말기 RA의 치료에 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물은 이전에 항-TNF-α 치료법을 받은 환자를 치료하기 위한 것이다. 특정 구현예에서, 치료될 환자는 항-TNF-α 치료법에 반응하지 않거나 더 이상 반응하지 않는다.
본 발명의 조성물은 환자의 면역계를 조절하는 데 유용할 수 있기 때문에, 특정 구현예에서, 본 발명의 조성물은 RA의 위험이 있다고 밝혀지거나 초기 단계 RA로 진단된 환자에서 RA를 예방하는 데 사용하기 위한 것이다. 본 발명의 조성물은 RA의 발생을 예방하는 데 유용할 수 있다.
본 발명의 조성물은 RA를 관리하거나 경감시키는 데 유용할 수 있다. 본 발명의 조성물은 관절 팽윤 또는 골 파괴와 관련된 증상을 감소시키는 데 특히 유용할 수 있다. RA의 치료 또는 예방은 예를 들어 증상의 중증도의 완화 또는 악화 빈도의 감소 또는 환자에게 문제가 되는 유발 요인의 범위를 나타낼 수 있다.
다발성 경화증
바람직한 구현예에서, 본 발명의 조성물은 다발성 경화증의 치료 또는 예방에 사용하기 위한 것이다. 본 발명의 조성물은 다발성 경화증의 마우스 모델 (EAE 모델)에서 질환 발병률 및 질환 중증도에서의 감소를 달성할 수 있고, 그래서 이들은 다발성 경화증의 치료 또는 예방에서 유용할 수 있다. 다발성 경화증은 특히 뇌와 척수에서의 신경 세포의 수초 외피에 손상을 일으키는 염증성 질환이다. 다발성 경화증은 만성 질환으로 점차적으로 무력화되고 에피소드로 진화한다. 예를 들어 IL-17 수치가 다발성 경화증 병변과 관련이 있고 IL-17이 혈액 뇌 장벽 내피 세포 결막을 파괴할 수 있고 Th17 세포가 중심 신경계로 이동하여 신경 손실을 일으킬 수 있기 때문에 IL-17 및 Th17 세포는 다발성 경화증에서 핵심적인 역할을 할 수 있다[46, 47]. 따라서, 본 발명의 조성물은 다발성 경화증의 예방 또는 치료에 특히 효과적일 수 있다.
특정 구현예에서, 본 발명의 조성물로 치료하면 질병 발병 또는 질병 중증도가 감소한다. 특정 구현예에서, 본 발명의 조성물은 질병 발병 또는 질병 중증도를 감소시키는 데 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 치료하면 운동 기능의 저하가 방지되거나 운동 기능이 향상된다. 특정 구현예에서, 본 발명의 조성물은 운동 기능의 저하 또는 운동 기능의 개선에 사용하기 위한 것이다. 특정 구현예에서, 본 발명의 조성물로 치료하면 마비의 발병을 예방할 수 있다. 특정 구현예에서, 본 발명의 조성물은 다발성 경화증의 치료에서 마비를 예방하는 데 사용하기 위한 것이다.
본 발명의 조성물은 환자의 면역계를 조절하는 데 유용할 수 있으며, 따라서 특정 구현예에서, 본 발명의 조성물은 다발성 경화증의 위험이 있는 것으로 확인되었거나 초기 단계의 다발성 경화증 또는 "재발-완화형" 다발성 경화증으로 진단된 환자에서 다발성 경화증을 예방하는 데 사용하기 위한 것이다. 본 발명의 조성물은 경화증 발병을 예방하는데 유용할 수 있다.
본 발명의 조성물은 다발성 경화증을 치료 또는 경감시키는 데 유용할 수 있다. 본 발명의 조성물은 다발성 경화증과 관련된 증상을 감소시키는 데 특히 유용할 수 있다. 다발성 경화증의 치료 또는 예방은 예를 들어 증상의 중증도의 완화 또는 악화 빈도의 감소 또는 환자에게 문제가 되는 유발 인자의 범위를 나타낼 수 있다.
투여 방식
바람직하게는, 본 발명의 조성물은 본 발명의 박테리아 균주로 장내 수송 및/또는 부분적 또는 전체 콜로니화를 가능하게 하기 위해 위장관에 투여될 수 있다. 일반적으로, 본 발명의 조성물은 경구 투여되지만, 직장, 비내, 또는 협측 또는 설하 경로를 통해 투여될 수 있다.
특정 구현예에서, 본 발명의 조성물은 발포체로서, 스프레이 또는 겔로서 투여될 수 있다.
특정 구현예에서, 본 발명의 조성물은 예를 들어 테오브로마 오일(코코아 버터), 합성 경질 지방(예를 들어, 붕해제, 위텝솔), 글리세로-젤라틴, 폴리에틸렌 글리콜, 또는 비누 글리세린 조성물의 형태로 직장 좌약과 같은 좌약으로서 투여될 수 있다.
특정 구현예에서, 본 발명의 조성물은 비위관, 위관, 위선, 공막 절개관(J 관), 경피 내시경 위장관(PEG), 또는 포트 예컨대 위장, 공장 및 기타 적합한 액세스 포트에 대한 액세스를 제공하는 흉벽 포트와 같은 관을 통해 위장관으로 투여된다.
본 발명의 조성물은 한번 투여될 수 있거나, 치료 요법의 일부로서 순차적으로 투여될 수 있다. 특정 구현예에서, 본 발명의 조성물은 매일 투여될 수 있다.
본 발명의 특정 구현예에서, 본 발명에 따른 치료는 환자의 장내 미생물의 평가를 동반한다. 본 발명의 균주로의 수송 및/또는 부분적 또는 전체 콜로니화가 달성되지 않아 유효성이 관찰되지 않는 경우 치료는 반복되거나 또는 수송 및/또는 부분적 또는 전체 콜로니화가 성공적으로 이루어지고 효능이 관찰되는 경우 치료는 중단될 수 있다.
특정 구현예에서, 본 발명의 조성물은 자궁속 및/또는 태어난 후에 아이에서 발생하는 염증성 또는 자가면역 질환을 예방하기 위해 임신 동물 예를 들어 인간과 같은 포유동물에 투여될 수 있다.
본 발명의 조성물은 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태로 진단되거나 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태의 위험이 있는 것으로 확인된 환자에게 투여될 수 있다. 상기 조성물은 또한 건강한 환자에서 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 증상의 발병을 예방하기 위한 예방적 조치로서 투여될 수 있다.
본 발명의 조성물은 비정상적인 내장 미생물을 갖는 것으로 확인된 환자에게 투여될 수 있다. 예를 들어, 환자는 에리시펠라토클로스트리디움에 의해 감소된 또는 결여된 군집화를 가질 수 있다.
본 발명의 조성물은 영양 보충제와 같은 식품으로 투여될 수 있다.
일반적으로, 본 발명의 조성물은 가금류, 돼지, 고양이, 개, 말 또는 토끼와 같은 단포 포유동물을 비롯한 동물을 치료하는 데 사용될 수 있지만, 인간의 치료를 위한 것이다. 본 발명의 조성물은 동물의 성장 및 성능을 향상시키는 데 유용할 수 있다. 동물에게 투여하면, 경구용 위관 영양법을 사용할 수 있다.
조성물
일반적으로, 본 발명의 조성물은 박테리아를 포함한다. 본 발명의 바람직한 구현예에서, 조성물은 동결-건조된 형태로 제형화된다. 예를 들어, 본 발명의 조성물은 본 발명의 박테리아 균주를 포함하는 과립 또는 젤라틴 캡슐 예를 들어 경질 젤라틴 캡슐을 포함할 수 있다.
바람직하게는, 본 발명의 조성물은 동결 건조된 박테리아를 포함한다. 박테리아의 동결 건조는 잘 확립된 절차이며 관련 지침은 예를 들어 참고문헌[48, 49, 50]에서 얻을 수 있다.
대안적으로, 본 발명의 조성물은 살아있는 활성 박테리아 배양물을 포함할 수 있다.
일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 불활성화되지 않았고, 예를 들어, 열-불활성화되지 않았다. 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 사멸되지 않았고, 예를 들어, 열-사멸되지 않았다. 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 약화되지 않았고, 예를 들어, 열-약화되지 않았다. 예를 들어, 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 사멸, 불활성화 및/또는 약화되지 않았다. 예를 들어, 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 살아있다. 예를 들어, 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 생존가능하다. 예를 들어, 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 장에서 부분적으로 또는 전적으로 군집할 수 있다. 예를 들어, 일부 구현예에서, 본 발명의 조성물에서 박테리아 균주는 생존가능하고 장에서 부분적으로 또는 전적으로 군집할 수 있다.
일부 구현예에서, 조성물은 살아있는 박테리아 균주 및 사멸되어 있는 박테리아 균주의 혼합물을 포함한다.
바람직한 구현예에서, 본 발명의 조성물은 박테리아 균주를 장내로 수송할 수 있도록 캡슐화된다. 캡슐화는 예를 들어 압력, 효소 활성 또는 pH의 변화에 의해 유발될 수 있는 물리적 붕괴와 같은 화학적 또는 물리적 자극에 의한 파열을 통해 표적 위치로 수송될 때까지 조성물이 분해되지 않도록 보호한다. 임의의 적절한 캡슐화 방법이 사용될 수 있다. 예시적인 캡슐화 기술은 다공성 매트릭스 내의 포착, 고체 담체 표면상의 부착 또는 흡착, 응집 또는 가교 결합제에 의한 자기 응집 및 미세다공성 막 또는 마이크로캡슐 후의 기계적 봉쇄를 포함한다. 본 발명의 조성물을 제조하는 데 유용한 캡슐화에 대한 지침은 예를 들어 참고문헌 [51] 및 [52]에서 이용가능하다.
상기 조성물은 경구 투여될 수 있고, 정제, 캡슐 또는 분말의 형태일 수 있다. 캡슐화된 생성물이 바람직한 것은 에리시펠라토클로스트리디움 라모숨 이 산소성생물이기 때문이다. 기타 성분(예컨대, 비타민 C, 예를 들어)은 생체 내에서 수송 및/또는 부분적 또는 전체 콜로니화 및 생존을 개선하기 위해 산소 제거제 및 프리바이오틱 기질로서 포함될 수 있다. 대안적으로, 본 발명의 프로바이오틱 조성물은 우유 또는 유청 기반의 발효 낙농 제품과 같은 식품 또는 영양 제품 또는 의약품으로서 경구 투여될 수 있다.
상기 조성물은 프로바이오틱으로 제형화될 수 있다.
본 발명의 조성물은 치료 유효량의 본 발명의 박테리아 균주를 포함한다. 치료 유효량의 박테리아 균주는 환자에게 유익한 효과를 발휘하기에 충분하다. 박테리아 균주의 치료학적 유효량은 환자의 장내 수송 및/또는 부분적 또는 전체 콜로니화를 초래하기에 충분할 수 있다.
예를 들어, 성인 인간에 대한 박테리아의 적합한 일일 투여량은 약 1 x 103 내지 약 1 x 1011 콜로니 형성 단위(CFU)일 수 있고; 예를 들어, 약 1 x 107 내지 약 1 x 1010 CFU; 다른 예에서는 약 1 x 106 내지 약 1 x 1010 CFU이다.
특정 구현예에서, 조성물은 조성물의 중량에 대하여 약 1 x 106 내지 약 1 x 1011 CFU/g의 양으로 박테리아 균주를 함유한다; 예를 들어, 약 1 x 108 내지 약 1 x 1010 CFU/g이다. 투여량은 예를 들어 1g, 3g, 5g 및 10g일 수 있다.
전형적으로, 본 발명의 조성물과 같은 프로바이오틱은 임의로 적어도 하나의 적합한 프리바이오틱 화합물과 배합된다. 프리바이오틱 화합물은 일반적으로 올리고- 또는 폴리사카라이드 또는 설탕 알코올과 같은 비-소화성 탄수화물이며, 이는 상부 소화관에서 분해되거나 흡수되지 않는다. 공지의 프리바이오틱은 이눌린 및 트랜스갈락토-올리고사카라이드와 같은 시판 중인 제품을 포함한다.
특정 구현예에서, 본 발명의 프로바이오틱 조성물은 총 중량 조성물에 대해 약 1 내지 약 30 중량%(예를 들어, 5 내지 20 중량%)의 양으로 프리바이오틱 화합물을 포함한다. 탄수화물은 하기로 이루어진 군으로부터 선택될 수 있다:프룩토-올리고사카라이드(또는 FOS), 단쇄 프룩토-올리고사카라이드, 이눌린, 이소말토-올리고사카라이드, 펙틴, 자일로-올리고사카라이드(또는 XOS), 키토산-올리고사카라이드(또는 COS), 베타-글루칸, 경질 검 개질 및 저항성 전분, 폴리덱스트로스, D-타가토스, 아카시아 섬유, 캐롭, 귀리 및 감귤류 섬유.하나의 측면에서, 프리바이오틱은 단쇄 프룩토오스-올리고사카라이드(이하, 간단히 FOSs-c.c로 나타냄)이다; 상기 FOSs-c.c는 일반적으로 사탕무 설탕의 전환에 의해 얻어지고 3개의 글루코오스 분자가 결합된 사카로스 분자를 포함하는 소화가 가능한 탄수화물은 아니다.
본 발명의 조성물은 약학적으로 허용가능한 부형제 또는 담체를 포함할 수 있다. 적합한 부형제의 예는 참고문헌 [53]에서 확인할 수 있다. 치료적 사용을 위한 허용가능한 담체 또는 희석제는 약학 분야에 잘 알려져 있으며, 예를 들어 문헌 [54]에 기재되어 있다. 적합한 담체의 예로는 락토오스, 전분, 글루코오스, 메틸 셀룰로오스, 마그네슘 스테아레이트, 만니톨, 솔비톨 등이 포함된다. 적합한 희석제의 예는 에탄올, 글리세롤 및 물을 포함한다. 약학적 담체, 부형제 또는 희석제의 선택은 의도된 투여 경로 및 표준 약제 실습과 관련하여 선택될 수 있다. 약학적 조성물은 담체, 부형제 또는 희석제로서 또는 이들 외에 임의의 적합한 결합제, 윤활제, 현탁화제, 코팅제, 가용화제를 포함할 수 있다. 적합한 결합제의 예는 전분, 젤라틴, 천연 당류 예컨대 글루코오스, 무수 락토오스, 자유-유동 락토오스, 베타-락토오스, 옥수수 감미료, 천연 및 합성 검 예컨대 아카시아, 트라가칸트 또는 나트륨 알기네이트, 카복시메틸 셀룰로오스 및 폴리에틸렌 글리콜을 포함한다. 적합한 윤활제의 예로는 올레산 나트륨, 스테아린산 나트륨, 스테아린산 마그네슘, 안식향산 나트륨, 아세트산 나트륨, 염화나트륨 등이 포함된다. 보존제, 안정화제, 염료 및 향미제조차도 약학 조성물 중에 제공될 수 있다. 보존제의 예는 나트륨 벤조에이트, 소르브산 및 p-하이드록시벤조산의 에스테르를 포함한다. 항산화제 및 현탁화제가 또한 사용될 수 있다.
본 발명의 조성물은 식품으로서 제형화될 수 있다. 예를 들어, 식품은 영양 보충제와 같이 본 발명의 치료 효과 이외에 영양적인 이득을 제공할 수 있다. 유사하게, 식품 조성물은 본 발명의 조성물의 맛을 증강시키거나 또는 약학 조성물보다는 일반적인 식품 품목에 보다 유사함으로써 조성물을 소비하기에 더 매력적이도록 제형화될 수 있다. 특정 구현예에서, 본 발명의 조성물은 우유-기재 제품으로 제형화된다. "우유-기재 제품"이란 용어는 다양한 지방 함량을 갖는 액체 또는 반고체 우유 또는 유청 기반 제품을 의미한다. 우유-기재 제품은 예를 들어 암소 우유, 염소 우유, 양 우유, 탈지유, 전유, 분유로부터 재조합된 우유 및 임의의 비-가공 우유 또는 가공된 제품 예를 들어 요구르트, 응유, 커드(curd), 산유, 산전유, 버터 밀크 및 다른 산유 제품일 수 있다. 또 다른 중요한 그룹에는 우유 음료, 예를 들어 유장 음료, 발효 우유, 응축 우유, 유아 또는 아기용 우유와; 맛을 낸 우유, 아이스크림; 과자와 같은 우유-함유 식품이 포함된다.
일부 구현예에서, 본 발명의 조성물은 속 에리시펠라토클로스트리디움의 하나 이상의 박테리아 균주를 포함하고 임의의 다른 속으로부터 박테리아를 함유하지 않거나, 또 다른 속으로부터 박테리아의 겨우 최소한 또는 생물학적으로 무관한 양을 포함한다. 따라서, 일부 구현예에서, 본 발명은, 치료법에서, 임의의 다른 속으로부터 박테리아를 함유하지 않거나 또 다른 속으로부터 박테리아의 겨우 최소한 또는 생물학적으로 무관한 양을 포함하는, 속 에리시펠라토클로스트리디움의 하나 이상의 박테리아 균주를 포함하는 조성물을 제공한다.
특정 구현예에서, 본 발명의 조성물은 단일 박테리아 균주 또는 종을 함유하고 임의의 다른 박테리아 균주 또는 종을 함유하지 않는다. 이러한 조성물은 다른 박테리아 균주 또는 종의 최소한 또는 생물학적으로 무관한 양만을 포함할 수 있다. 이러한 조성물은 다른 유기체 종이 실질적으로 없는 배양물일 수 있다. 따라서, 일부 구현예에서, 본 발명은 치료법에서 사용하기 위해 임의의 다른 속으로부터 박테리아를 함유하지 않거나 또 다른 속으로부터 박테리아의 겨우 최소한 또는 생물학적으로 무관한 양을 포함하는, 속 에리시펠라토클로스트리디움의 단일 박테리아 균주 또는 종을 포함하는 조성물을 제공한다.
일부 구현예에서, 본 발명의 조성물은 1 초과 박테리아 균주 또는 종을 포함한다. 예를 들어, 일부 구현예에서, 본 발명의 조성물은 동일한 종 내로부터 1 초과 균주 (예를 들면 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40 또는 45 초과 균주) 를 포함하고, 선택적으로, 임의의 다른 종으로부터 박테리아를 함유하지 않는다. 일부 구현예에서, 본 발명의 조성물은 동일한 종 내로부터 50 미만 균주 (예를 들면 45, 40, 35, 30, 25, 20, 15, 12, 10, 9, 8, 7, 6, 5, 4 또는 3 미만 균주)를 포함하고, 선택적으로, 임의의 다른 종으로부터 박테리아를 함유하지 않는다. 일부 구현예에서, 본 발명의 조성물은 동일한 종 내로부터 1-40, 1-30, 1-20, 1-19, 1-18, 1-15, 1-10, 1-9, 1-8, 1-7, 1-6, 1-5, 1-4, 1-3, 1-2, 2-50, 2-40, 2-30, 2-20, 2-15, 2-10, 2-5, 6-30, 6-15, 16-25, 또는 31-50 균주를 포함하고, 선택적으로, 임의의 다른 종으로부터 박테리아를 함유하지 않는다. 일부 구현예에서, 본 발명의 조성물은 동일한 속 내로부터 1 초과 종 (예를 들면 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 15, 17, 20, 23, 25, 30, 35 또는 40 초과 종)을 포함하고, 선택적으로, 임의의 다른 속으로부터 박테리아를 함유하지 않는다. 일부 구현예에서, 본 발명의 조성물은 동일한 속 내로부터 50 미만 종 (예를 들면 50, 45, 40, 35, 30, 25, 20, 15, 12, 10, 8, 7, 6, 5, 4 또는 3 미만 종)을 포함하고, 선택적으로, 임의의 다른 속으로부터 박테리아를 함유하지 않는다. 일부 구현예에서, 본 발명의 조성물은 동일한 속 내로부터 1-50, 1-40, 1-30, 1-20, 1-15, 1-10, 1-9, 1-8, 1-7, 1-6, 1-5, 1-4, 1-3, 1-2, 2-50, 2-40, 2-30, 2-20, 2-15, 2-10, 2-5, 6-30, 6-15, 16-25, 또는 31-50 종을 포함하고, 선택적으로, 임의의 다른 속으로부터 박테리아를 함유하지 않는다. 본 발명은 전술한 것의 임의의 조합을 포함한다.
일부 구현예에서, 조성물은 미생물 컨소시엄을 포함한다. 예를 들어, 일부 구현예에서, 조성물은 미생물 컨소시엄의 일부로서 에리시펠라토클로스트리디움 박테리아 균주를 포함한다. 예를 들어, 일부 구현예에서, 에리시펠라토클로스트리디움 박테리아 균주는 장에서 생체내 공생적으로 살 수 있는 다른 속으로부터 하나 이상의 (예를 들면 적어도 2, 3, 4, 5, 10, 15 또는 20) 다른 박테리아 균주와 조합으로 존재한다. 예를 들어, 일부 구현예에서, 조성물은 상이한 속으로부터 박테리아 균주와 조합으로 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함한다. 일부 구현예에서, 미생물 컨소시엄은 단일 유기체, 예를 들면 인간의 대변 샘플로부터 수득된 2개 이상의 박테리아 균주를 포함한다. 일부 구현예에서, 미생물 컨소시엄은 사실상 함께 발견되지 않는다. 예를 들어, 일부 구현예에서, 미생물 컨소시엄은 적어도 2개의 상이한 유기체의 대변 샘플로부터 수득된 박테리아 균주를 포함한다. 일부 구현예에서, 2개의 상이한 유기체는 동일한 종, 예를 들면 2명의 상이한 인간이다. 일부 구현예에서, 2개의 상이한 유기체는 영아 인간 및 성인 인간이다. 일부 구현예에서, 2개의 상이한 유기체는 인간 및 비-인간 포유동물이다.
일부 구현예에서, 본 발명의 조성물은 NCIMB 42688로서 기탁된 균주 MRX027과 동일한 안전성 및 치료 효능 특징을 갖지만, NCIMB 42688로서 기탁된 MRX027이 아니거나, 에리시펠라토클로스트리디움 라모숨 이 아니거나 에리시펠라토클로스트리디움이 아닌 박테리아 균주를 추가적으로 포함한다.
본 발명의 조성물이 1 초과 박테리아 균주, 종 또는 속을 포함하는 일부 구현예에서, 개별적인 박테리아 균주, 종 또는 속은 개별, 동시 또는 순차적인 투여를 위한 것일 수 있다. 예를 들어, 조성물은 1 초과 박테리아 균주, 종 또는 속의 모두를 포함할 수 있거나, 박테리아 균주, 종 또는 속은 개별적으로 저장될 수 있고 개별적으로, 동시에 또는 순차적으로 투여될 수 있다. 일부 구현예에서, 1 초과 박테리아 균주, 종 또는 속은 개별적으로 저장되지만 사용에 앞서 함께 혼합된다.
일부 구현예에서, 본 발명에서 사용하기 위한 박테리아 균주는 인간 성인 대변으로부터 수득된다. 본 발명의 조성물이 1 초과 박테리아 균주를 포함하는 일부 구현예에서, 모든 박테리아 균주는 인간 성인 대변으로부터 수득되거나 다른 박테리아 균주가 존재하면 이들은 최소한 양으로만 존재한다. 박테리아는 인간 성인 대변으로부터 수득된 및 본 발명의 조성물에서 사용된 다음 배양되어질 수 있다.
상기에서 언급된 바와 같이, 일부 구현예에서, 하나 이상의 에리시펠라토클로스트리디움 박테리아 균주는 본 발명의 조성물에서 단지 치료적으로 활성제(들)이다. 일부 구현예에서, 조성물에서 박테리아 균주(들)은 본 발명의 조성물에서 단지 치료적으로 활성제(들)이다.
본 발명에 따라 사용하기 위한 조성물은 시판 승인을 필요로 할 수도 있고 필요로 하지 않을 수도 있다.
특정 구현예에서, 본 발명은 상기 박테리아 균주가 동결건조되는 약학적 조성물을 제공한다. 특정 구현예에서, 본 발명은 상기 박테리아 균주가 분무 건조되는 상기 약제학적 조성물을 제공한다. 특정 구현예에서, 본 발명은 상기 박테리아 균주가 동결건조되거나 분무 건조되고 살아있는 상기 약제학적 조성물을 제공한다. 특정 구현예에서, 본 발명은 상기 박테리아 균주가 동결건조되거나 분무 건조되고 생존가능한 상기 약제학적 조성물을 제공한다. 특정 구현예에서, 본 발명은 상기 박테리아 균주가 동결건조되거나 분무 건조되고 장에서 부분적으로 또는 전적으로 군집할 수 있는 상기 약제학적 조성물을 제공한다. 특정 구현예에서, 본 발명은 상기 박테리아 균주가 동결건조되거나 분무 건조되고 생존가능하고 장에서 부분적으로 또는 전적으로 군집할 수 있는 상기 약제학적 조성물을 제공한다.
일부 경우에, 동결건조된 또는 분무 건조된 박테리아 균주는 투여에 앞서 재구성된다. 일부의 경우, 재구성은 본원에 기재된 희석제의 사용에 의한다.
본 발명의 조성물은 약학적으로 허용가능한 부형제, 희석제 또는 담체를 포함할 수 있다.
특정 구현예에서, 본 발명은 하기를 포함하는 약학적 조성물을 제공한다:본 발명에서 사용된 바와 같이 박테리아 균주; 및 약학적으로 허용가능한 부형제, 캐리어 또는 희석제; 여기서 상기 박테리아 균주는 필요로 하는 대상체에 투여된 경우 장애를 치료하는 데 충분한 양이고; 여기서 상기 장애는 하기로 이루어진 군으로부터 선택된다: 포도막염; 암, 예컨대 유방암, 폐암, 간암, 결장암, 또는 난소암; 다발성 경화증; 관절염, 예컨대 류마티스성 관절염, 골관절염, 건선성 관절염, 또는 유년성 특발성 관절염; 시신경척수염 (데빅병); 강직 척추염; 척추관절염; 건선; 전신 홍반성 낭창; 염증성 장 질환, 예컨대 크론병 또는 궤양성 대장염; 소아지방변증; 천식, 예컨대 알러지성 천식 또는 호중구성 천식; 만성 폐쇄성 폐 질환 (COPD); 공막염; 혈관염; 베체트병; 죽상경화증; 아토피 피부염; 폐공기증; 치주염; 알러지성 비염; 및 동종이식편 거부반응.
특정 구현예에서, 본 발명은 하기를 포함하는 약학적 조성물을 제공한다:본 발명에서 사용된 바와 같이 박테리아 균주; 및 약학적으로 허용가능한 부형제, 캐리어 또는 희석제; 여기서 상기 박테리아 균주는 IL-17 또는 Th17 경로에 의해 매개된 질환 또는 병태를 치료 또는 예방하는 데 충분한 양이다. 바람직한 구현예에서, 상기 질환 또는 병태는 하기로 이루어진 군으로부터 선택된다: 포도막염; 암, 예컨대 유방암, 폐암, 간암, 결장암, 또는 난소암; 다발성 경화증; 관절염, 예컨대 류마티스성 관절염, 골관절염, 건선성 관절염, 또는 유년성 특발성 관절염; 시신경척수염 (데빅병); 강직 척추염; 척추관절염; 건선; 전신 홍반성 낭창; 염증성 장 질환, 예컨대 크론병 또는 궤양성 대장염; 소아지방변증; 천식, 예컨대 알러지성 천식 또는 호중구성 천식; 만성 폐쇄성 폐 질환 (COPD); 공막염; 혈관염; 베체트병; 죽상경화증; 아토피 피부염; 폐공기증; 치주염; 알러지성 비염; 및 동종이식편 거부반응.
특정 구현예에서, 본 발명은 박테리아 균주의 양이 조성물의 중량에 대하여 약 1 x 103 내지 약 1 x 1011 콜로니 형성 단위/g인 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 조성물이 1 g, 3 g, 5 g 또는 10 g의 투여량으로 투여되는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 경구, 직장, 피하, 비강, 협측 및 설하로 이루어진 군으로부터 선택된 방법에 의해 조성물이 투여되는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 락토오스, 전분, 글루코오스, 메틸 셀룰로오스, 마그네슘 스테아레이트, 만니톨 및 솔비톨로 이루어진 군으로부터 선택된 담체를 포함하는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 에탄올, 글리세롤 및 물로 이루어진 군으로부터 선택된 희석제를 포함하는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 전분, 젤라틴, 글루코오스, 무수 락토오스, 자유-유동 락토오스, 베타-락토오스, 옥수수 감미료, 아카시아, 트라가칸트, 알긴산 나트륨, 카복시메틸 셀룰로오스, 폴리에틸렌 글리콜, 올레산 나트륨, 스테아르 산 나트륨, 스테아르산 마그네슘, 안식향산 나트륨, 아세트산 나트륨 및 염화나트륨으로 이루어진 군으로부터 선택되는 부형제를 포함하는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 보존제, 항산화제 및 안정화제 중 적어도 하나를 추가로 포함하는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 나트륨 벤조에이트, 소르브산 및 p-하이드록시벤조산의 에스테르로 이루어진 군으로부터 선택된 보존제를 포함하는 상기 약학적 조성물을 제공한다.
특정 구현예에서, 본 발명은 조성물을 약 4℃ 또는 약 25℃에서 밀봉된 용기에 저장하고 상기 용기를 50% 상대 습도를 갖는 대기에 두었을 때, 콜로니 형성 단위로 측정한 박테리아 균주의 적어도 80%가 적어도 약 하기의 기간 이후 남아있는 상기 약학적 조성물을 제공한다:1 개월, 3 개월, 6 개월, 1 년, 1.5 년, 2 년, 2.5 년 또는 3 년.
일부 구현예에서, 본 발명의 조성물은 본원에서 기재된 바와 같이 조성물을 포함하는 밀봉된 용기로 제공된다. 일부 구현예에서, 밀봉된 용기는 샤세트 또는 병이다. 일부 구현예에서, 본 발명의 조성물은 본원에서 기재된 바와 같이 조성물을 포함하는 주사기로 제공된다.
본 발명의 조성물은, 일부 구현예에서, 약제학적 제형으로서 제공될 수 있다. 예를 들어, 조성물은 정제 또는 캡슐로서 제공될 수 있다. 일부 구현예에서, 캡슐은 젤라틴 캡슐 (“겔-캡”)이다.
일부 구현예에서, 본 발명의 조성물은 경구로 투여된다. 경구 투여는 화합물이 위장관에 들어가도록 연하 및/또는 화합물이 입으로부터 직접적으로 혈류에 들어가는 구강, 혀, 또는 설하 투여를 포함할 수 있다.
경구 투여에 적합한 약제학적 제형은 하기를 포함한다: 고형 플러그, 고형 미세미립자, 반-고체 및 액체 (다중 상 또는 분산된 시스템 포함) 예컨대 정제; 다중- 또는 나노-미립자, 액체 (예를 들면 수용액), 에멀젼 또는 분말을 함유하는 연질 또는 경질 캡슐; 로젠지 (액체-충전된 것 포함); 츄스; 겔; 빠른 분산 복용 형태; 필름; 질좌약; 스프레이; 및 구강/점막접착성 패치.
일부 구현예에서 약제학적 제형은 경구 투여로 장에 본 발명의 조성물의 전달에 적합한 장용성 제형, 즉 위-저항성 (예를 들어, 위 pH에 저항성) 제형이다. 장용성 제형은 조성물의 박테리아 또는 또 다른 성분이 산-감수성인, 예를 들면 위 병태하에 분해하기 쉬운 경우 특히 유용할 수 있다.
일부 구현예에서, 장용성 제형은 장용 코팅물을 포함한다. 일부 구현예에서, 제형은 장용 코팅된 복용 형태이다. 예를 들어, 제형은 장용 코팅된 정제 또는 장용 코팅된 캡슐, 등등일 수 있다. 장용 코팅물은 경구 전달을 위한 종래의 장용 코팅물, 예를 들어, 정제, 캡슐, 등등용 종래의 코팅물일 수 있다. 제형은 필름 코팅물, 예를 들어, 장용성 폴리머, 예를 들면 산-불용성 폴리머의 박막 층을 포함할 수 있다.
일부 구현예에서, 장용성 제형은 장용 코팅물에 대한 필요 없이 본질적으로 장용성, 예를 들어, 위-저항성이다. 따라서, 일부 구현예에서, 제형은 장용 코팅물을 포함하지 않는 장용성 제형이다. 일부 구현예에서, 제형은 열겔화 물질로부터 제조된 캡슐이다. 일부 구현예에서, 열겔화 물질은 셀룰로오스 물질, 예컨대 메틸셀룰로오스, 하이드록시메틸셀룰로오스 또는 하이드록시프로필메틸셀룰로오스 (HPMC)이다. 일부 구현예에서, 캡슐은 임의의 막 형성 폴리머를 함유하지 않는 외피를 포함한다. 일부 구현예에서, 캡슐은 외피를 포함하고 외피는 하이드록시프로필메틸셀룰로오스를 포함하고 임의의 막 형성 폴리머를 포함하지 않는다 (예를 들면 참고 [55]). 일부 구현예에서, 제형은 본질적으로 장용성 캡슐이다 (예를 들어, Capsugel제 Vcaps®).
일부 구현예에서, 제형은 연질 캡슐이다. 연질 캡슐은, 캡슐 외피에서 존재하는, 연화제, 예컨대, 예를 들어, 글리세롤, 소르비톨, 말티톨 및 폴리에틸렌 글리콜의 첨가 때문에, 특정 탄력성 및 유연도를 가질 수 있는 캡슐이다. 연질 캡슐은, 예를 들어, 젤라틴 또는 전분에 기초하여 생산될 수 있다. 젤라틴-기재 연질 캡슐은 다양한 공급자로부터 상업적으로 입수가능하다. 투여의 방법에 의존하여, 예컨대, 예를 들어, 경구로 또는 직장으로, 연질 캡슐은 다양한 형상을 가질 수 있고, 이들은, 예를 들어, 원통형, 타원형, 직사각형 또는 어뢰형일 수 있다. 연질 캡슐은 종래의 방법으로, 예컨대, 예를 들어, 쉬어러(Scherer) 방법, 악코겔(Accogel) 방법 또는 액적 또는 취입 방법으로 생산될 수 있다.
배양 방법
본 발명에 사용하기 위한 박테리아 균주는 예를 들어 참고 참고문헌 [56]-[58]에 기재된 표준 미생물 기술을 사용하여 배양될 수 있다.
배양에 사용되는 고체 또는 액체 배지는 YCFA 한천 또는 YCFA 배지일 수 있다. YCFA 배지는 하기를 포함할 수 있다(100ml 당, 근사값): 카시톤 (1.0 g), 효모 추출물 (0.25 g), NaHCO3 (0.4 g), 시스테인 (0.1 g), K2HPO4 (0.045 g), KH2PO4 (0.045 g), NaCl (0.09 g), (NH4)2SO4 (0.09 g), MgSO4, · 7H2O (0.009 g), CaCl2 (0.009 g), 레사주린 (0.1 mg), 헤민 (1 mg), 바이오틴 (1 μg), 코발라민 (1 μg), p-아미노벤조산 (3 μg), 엽산 (5 μg), 및 피리독사민 (15 μg).
백신 조성물에 사용하기 위한 박테리아 균주
본 발명자들은 본 발명의 박테리아 균주가 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태의 치료 또는 예방에 유용하다는 것을 확인하였다. 이는 본 발명의 박테리아 균주가 숙주 면역계에 미치는 효과의 결과일 가능성이있다. 따라서, 본 발명의 조성물은 또한 백신 조성물로서 투여될 때 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 증상을 예방하는데 유용할 수 있다. 특정 상기 구현예에서, 본 발명의 박테리아 균주는 생존가능하다. 특정 상기 구현예에서, 본 발명의 박테리아 균주는 장에서 부분적으로 또는 전적으로 군집할 수 있다. 특정 상기 구현예에서, 본 발명의 박테리아 균주는 생존가능하고 장에서 부분적으로 또는 전적으로 군집할 수 있다. 다른 특정 상기 구현예에서, 본 발명의 박테리아 균주는 사멸, 불활성화 또는 약화될 수 있다. 이러한 특정 구현예에서, 조성물은 백신 보조제를 포함할 수 있다. 특정 구현예에서, 조성물은 피하 주사와 같은 주사를 통한 투여를 위한 것이다.
일반
본 발명의 실시는, 달리 명시하지 않는 한, 당해 분야의 숙련 범위 내에서 화학, 생화학, 분자생물학, 면역학 및 약리학의 통상적인 방법을 사용할 것이다. 이러한 기술은 문헌에 충분히 설명되어 있다. 참고, 예를 들면, 참고문헌 [59] 및 [60-66]등.
용어 "포함하는"은 "포함하는"뿐만 아니라 "이루어지는"을 포함하고, 예를 들면, X를 "포함하는" 조성물은 X만으로 이루어질 수 있거나, 예를 들어, 부가적인 것 예를 들어 하기를 포함할 수 있다: X + Y.
수치 x와 관련하여 "약"이라는 용어는 선택 사항이며 예를 들어 x 플마기호 10%를 의미한다.
"실질적으로"라는 용어는 "완전히" 제외하지 않고, 예를 들어 Y가 "실질적으로 없는" 조성물은 Y를 전혀 함유하지 않을 수 있다. 필요한 경우, "실질적으로"라는 용어는 본 발명의 정의로부터 생략될 수 있다.
2개의 뉴클레오타이드 서열 사이의 백분율 서열 동일성에 대한 언급은, 정렬시, 뉴클레오타이드의 백분율이 2개의 서열을 비교할 때 동일하다는 것을 의미한다. 이러한 정렬 및 퍼센트 상동성 또는 서열 동일성은 당해 기술 분야에 공지된 소프트웨어 프로그램 예를 들어 하기의 참고문헌 [67]의 섹션 7.7.18에 기재된 소프트웨어 프로그램을 사용하여 결정할 수 있다. 바람직한 정렬은 12의 갭 오픈 패널티 및 2의 갭 연장 패널티, 62의 BLOSUM 매트릭스를 수반한 아핀 갭 조사를 이용하는 스미쓰-워터맨(Smith-Waterman) 상동성 검색 알고리즘에 의해 결정된다. 스미쓰-워터맨 상동 검색 알고리즘은 참고문헌 [68]에 기술되어 있다.
특별히 언급하지 않는 한, 다수의 단계를 포함하는 공정 또는 방법은 상기 방법의 시작 또는 끝에서 추가적인 단계를 포함하거나, 또는 추가적인 개재 단계를 포함할 수 있다. 또한, 적절한 경우, 단계들은 결합되거나 생략되거나 대체 순서로 수행될 수 있다.
본 발명의 다양한 구현예가 본원에 기술된다. 각 구현예에서 특정된 특징은 추가의 구현예를 제공하기 위해 다른 특정 특징과 결합될 수 있음을 이해할 것이다. 특히, 본원에서 적합한, 전형적 또는 바람직한 것으로 강조되는 구현예는 (상호 배타적일 때를 제외하고) 서로 조합될 수 있다.
실시예
실시예 1 - 포도막염의 마우스 모델에서 박테리아 접종물의 효능
요약
본 연구는 포도막염에 관한 박테리아 투여의 효과를 시험하기 위해 인터포토리셉터 레티노이드-결합 단백질 (IRBP)-유도된 포도막염의 마우스 모델을 사용하였다. 포도막염은 안구내 염증 및 망막 조직 파괴에서 비롯한 시각을 위협하는 병태이다. 상기 질환은 실험적 자가면역 포도막망막염 (EAU)의 모델로 설치류에서 연구될 수 있다 [69]. EAU는 Th1/Th17 세포가 망막 항원을 향해 유도되고 조직 파괴를 초래하는 상주하는 및 침투하는 단핵 세포를 활성화하는 사이토카인을 생산하는 장기-특이적인 장애이다. EAU는 인터포토리셉터 레티노이드 결합 단백질 펩타이드 (IRBPp)를 포함하는 망막 항원으로 공격함으로써 마우스에서 유도될 수 있다. 질환 개시는 정상적으로 8-9 일째부터 발생하고 14-15 일째 이후 피크이다. 임상 질환의 징후는 국소 내시경 안저 이미지형성 (TEFI)을 이용하여 모니터링될 수 있다.
균주
MRX027:에리시펠라토클로스트리디움 라모숨.
이 실시예에서 사용된 균주는 NCIMB 42688로서 기탁되어 있다.
생물학적 치료는 글리세롤 스톡으로 제공되었다. 미생물학적 성장 배지 (YCFA)는 제제의 배양에 사용되었다.
마우스
마우스는 균주 C57BL/6이었고 연구의 초기에 6 주령 이상이었다. 72 마우스는 사용되었다 (+ 36 위성 동물). 병약한 동물은 연구로부터 제외되었다. 동물은 자동온도조절장치로 모니터링된 대기실 (22 ± 4 ℃)에서 특이적인 병원체 없는 (spf) 병태로 하우징되었다. 동물은 사용에 앞서 최소의 1 주 동안 표준 동물 하우스 병태하에 순응하게 되었다. 동물의 건강 상황은 상기 기간 내내 모니터링되었고 실험적 용도로 각각의 동물의 적합성은 연구 시작에 앞서 평가되었다. 마우스는 연구의 지속기간 동안 케이지당 최대 10 동물의 그룹으로 하우징되었다. 조사된 펠렛 다이어트 (Lab 다이어트, EU 설치류 다이어트 22%, 5LF5) 및 물은 순응 및 연구 기간 내내 선택적으로 이용가능하였다. 다이어트 또는 물의 임의의 구성요소가 연구를 방해하지 않았을 것 같다.
실험적 개요
성체 암컷 C57BL/6 마우스는 실험적 그룹으로 무작위로 위치되었고 1 주 동안 순응하게 되었다. 치료는 아래 계획에 따라 투여되었다. 0 일째, 동물은 피하 주사에 의해 2.5 mg/ml 마이코박테리움 투베르쿨로시스 H37 Ra로 보충된 완전한 프로인트 아쥬반트 (CFA)내 200 μg의 인터포토리셉터 레티노이드 결합 단백질 펩타이드 1-20 (IRBP p1-20)을 함유하는 에멀젼으로 투여되었다. 또한 0 일째, 동물은 복막내 주사에 의해 1.5 μg 보데텔라 페르투스시스 독소로 투여되었다. -14 일째부터, 동물은 주당 3회 계량된다. -1 일째부터 42 일째 실험의 끝까지, 동물은 국소 내시경 안저 이미지형성 (TEFI)을 이용하여 포도막염의 임상 징후에 대하여 매주 2회 모니터링된다.
투여 계획
모든 그룹은 n=12이다
경구 투여용 비히클은 YCFA 배지이다.
매일 2회 경구 투여용 투여 용적은 5 ml/kg이다.
양성 대조군 그룹은 약물 사이클로스포린 A로 치료를 이용하여 또한 시험되었다.
판독
체중.-14 일째부터, 동물은 1 주 3회 계량된다. 2 연속 사례로 그의 초기 (0 일째) 체중보다 15% 이상의 체중 감소를 가진 동물은 도태된다.
비-특이적 임상 관찰.-14 일째부터 실험의 끝까지, 동물은 비정상 자세 (굽은), 비정상 모질 상태 (털세움) 및 비정상 활성 수준 (감소된 또는 증가된 활성)을 포함하는 비-특이적 임상 징후에 대하여 매일 체크된다.
임상 점수:국소 내시경 안저 이미지형성 (TEFI)에 의한 망막 이미지형성.-1 일째부터 실험의 끝까지, 동물은 포도막염의 임상 징후에 대하여 매주 2회 채점된다. 망막 이미지는 트로피카마이드 1% 그 다음 페닐에프린 하이드로클로라이드 2.5%를 이용한 동공 팽창 이후 비-마취된 그러나 구속된 동물에서 TEFI를 이용하여 포착된다. 망막 이미지는 하기 시스템을 이용한 스코어이다. 최대 누적 스코어는 20이다.
결과
연구 결과는 도 1 및 2에 나타낸다.
임상 점수:국소 내시경 안저 이미지형성 (TEFI)에 의한 망막 이미지형성.0 일째부터 28 일째까지 대조군 그룹에서 측정된 TEFI 스코어 데이터는 비-매개변수 데이터에 대한 크루스칼-왈리스 시험 그 다음 실험적 일자 사이 다중 비교를 위한 던의 사후-시험에 의해 분석되었다.
IRBP 투여는 대조군 그룹에서 0 일째에 비교된 경우 14 일 (p < 0.01)째부터 및28 일 (p < 0.0001)째에 측정된 TEFI 스코어에서 유의미한 증가를 유도하였다 (도 1).
28 일째에 실험적 그룹에서 측정된 TEFI 스코어는 단방향 ANOVA를 이용하여 분석되었다. 예상대로, 스코어에서 상당한 감소는 양성 대조군 사이클로스포린 A 그룹에서 관측되었다. 음성 대조군에 비하여, MRX027-치료된 그룹 (p<0.05)에 대한 스코어에서 통계적으로 상당한 감소가 또한 있었다 (도 73).
결론. TEFI에 의해 결정된 임상 점수는, IRBP-유도된 포도막염의 상기 모델에서 예상대로, 14 일째부터 증가하였다. 28 일째까지, 질환 발병률 및 질환 중증도에서 놀랄만한 및 통계적으로 상당한 감소는 MRX027-치료된 그룹에서 관측되었고, 이는 양성 대조군 그룹에 대하여 보여진 것과 비교할만한 하였다. 특히, 이들 데이터는 균주 MRX027로 치료가 염증성 세포에 의한 망막 손상, 시신경 유두 염증 및/또는 망막 조직 침윤을 감소시켰다는 것을 나타낸다 (참조 상기 TEFI 망막 이미지 평점 체계). 이들 데이터는 균주 MRX027이 포도막염의 치료 또는 예방에 유용할 수 있다는 것을 나타낸다.
실시예 2 - 안정성 시험
본원에 기재된 적어도 하나의 박테리아 균주를 함유하는 본원에 기재된 조성물은 25℃ 또는 4℃에서 밀봉된 용기에 저장되고, 상기 용기는 30%, 40%, 50%, 60%, 70%, 75%, 80%, 90% 또는 95%의 상대 습도를 갖는 대기 중에 배치된다. 1 개월, 2 개월, 3 개월, 6 개월, 1 년, 1.5 년, 2 년, 2.5 년 또는 3 년 후, 박테리아 균주의 적어도 50%, 60%, 70%, 80% 또는 90%는 표준 프로토콜에 의해 결정된 콜로니 형성 단위로 측정시 그대로 유지되어야 한다.
서열
서열 식별 번호: 1 (에리시펠라토클로스트리디움 (클로스트리듐) 라모숨 16S rRNA 유전자, 균주 DSM 1402 - X73440)
서열 식별 번호: 2 (에리시펠라토클로스트리디움 라모숨 균주 JCM 1298 16S 리보솜
RNA 유전자, 부분 서열 - NR_113243.1)
서열 식별 번호: 3 (에리시펠라토클로스트리디움 라모숨 균주 MRX027에 대한 공통 16S rRNA 서열)
서열 식별 번호: 4 (에리시펠라토클로스트리디움 라모숨 균주 DSM 140의 게놈 서열) - 참고 전자 서열 목록.
참조문헌
SEQUENCE LISTING
<110> 4D PHARMA RESEARCH LIMITED
<120> COMPOSITIONS COMPRISING BACTERIAL STRAINS
<130> P067605
<150> GB 1520631.1
<151> 2015-11-23
<160> 4
<170> SeqWin2010, version 1.0
<210> 1
<211> 1526
<212> DNA
<213> Erysipelatoclostridium ramosum
<400> 1
nnnnnnngag agtttgatcc tggctcagga tgaacgctgg cggcgtgcct aatacatgca 60
agtcgaacgc gagcacttgt gctcgagtgg cgaacgggtg agtaatacat aagtaacctg 120
ccctagacag ggggataact attggaaacg gatagctaag accgcatagg tacggacact 180
gcatggtgac cgtattaaaa gtgcctcaaa gcactggtag aggatggact tatggcgcat 240
tagctggttg gcggggtaac ggcccaccaa ggcgacgatg cgtagccgac ctgagagggt 300
gaccggccac actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa 360
ttttcggcaa tgggggaaac cctgaccgag caacgccgcg tgaaggaaga aggttttcgg 420
attgtaaact tctgttataa agaagaacgg cggctacagg aaatggtagc cgagtgacgg 480
tactttattt tagaaagcca cggctaacta cgtgccagca gccgcggtaa tacgtaggtg 540
gcaagcgtta tccggaatta ttgggcgtaa agagggagca ggcggcagca agggtctgtg 600
gtgaaagcct gaagcttaac ttcagtaagc catagaaacc aggcagctag agtgcaggag 660
aggatcgtgg aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccagtg 720
gcgaaggcga cgatctggcc tgcaactgac gctcagtccc gaaagcgtgg ggagcaaata 780
ggattagata ccctagtagt ccacgccgta aacgatgagt actaagtgtt ggatgtcaaa 840
gttcagtgct gcagttaacg caataagtac tccgcctgag tagtacgttc gcaagaatga 900
aactcaaagg aattgacggg ggccgcacaa gcggtggagc atgtggttta attcgaagca 960
acgcgaagaa ccttaccagg tcttgacata ctcataaagg ctccagagat ggagagatag 1020
ctatatgaga tacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta 1080
agtcccgcaa cgagcgcaac ccttatcgtt agttaccatc attaagttgg ggactctagc 1140
gagactgcca gtgacaagct ggaggaaggc ggggatgacg tcaaatcatc atgcccctta 1200
tgacctgggc tacacacgtg ctacaatgga tggtgcagag ggaagcgaac cgcgaggtga 1260
agcaaaaccc ataaaaacca ttctcagttc ggattgtagt ctgcaactcg actacatgaa 1320
gttggaatcg ctagtaatcg cgaatcagca tgtcgcggtg aatacgttct cgggccttgt 1380
acacaccgcc cgtcacacca cgagagttga taacacccga agccggtggc ctaaccgcaa 1440
ggaaggagct gtctaaggtg ggattgatga ttggggtgaa gtcgtaacaa ggtatcccta 1500
cgggaacgtg cggctggatc acctcc 1526
<210> 2
<211> 1488
<212> DNA
<213> Erysipelatoclostridium ramosum
<400> 2
agagtttgat cctggctcag gatgaacgct ggcggcgtgc ctaatacatg caagtcgaac 60
gcgagcactt gtgctcgagt ggcgaacggg tgagtaatac ataagtaacc tgccctagac 120
agggggataa ctattggaaa cgatagctaa gaccgcatag gtacggacac tgcatggtga 180
ccgtattaaa agtgcctcaa agcactggta gaggatggac ttatggcgca ttagctggtt 240
ggcggggtaa cggcccacca aggcgacgat gcgtagccga cctgagaggg tgaccggcca 300
cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga attttcggca 360
atgggggaaa ccctgaccga gcaacgccgc gtgaaggaag aaggttttcg gattgtaaac 420
ttctgttata aaggaagaac ggcggctaca ggaaatggta gccgagtgac ggtactttat 480
tagaaagcca cggctaacta cgtgccagca gccgcggtaa tacgtaggtg gcaagcgtta 540
tccggaatta ttgggcgtaa agagggagca ggcggcagca agggtctgtg gtgaaagcct 600
gaagcttaac ttcagtaagc catagaaacc aggcagctag agtgcaggag aggatcgtgg 660
aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccagtg gcgaaggcga 720
cgatctggcc tgcaactgac gctcagtccc gaaagcgtgg ggagcaaata ggattagata 780
ccctagtagt ccacgccgta aacgatgagt actaagtgtt ggatgtcaaa gttcagtgct 840
gcagttaacg caataagtac tccgcctgag tagtacgttc gcaagaatga aactcaaagg 900
aattgacggg ggcccgcaca agcggtggag catgtggttt aattcgaagc aacgcgaaga 960
accttaccag gtcttgacat actcataaag gctccagaga tggagagata gctatatgag 1020
atacaggtgg tgcatggttg tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca 1080
acgagcgcaa cccttatcgt tagttaccat cattaagttg gggactctag cgagactgcc 1140
agtgacaagc tggaggaagg cggggatgac gtcaaatcat catgcccctt atgacctggg 1200
ctacacacgt gctacaatgg atggtgcaga gggaagcgaa gccgcgaggt gaagcaaaac 1260
ccataaaacc attctcagtt cggattgtag tctgcaactc gactacatga agttggaatc 1320
gctagtaatc gcgaatcagc atgtcgcggt gaatacgttc tcgggccttg tacacaccgc 1380
ccgtcacacc acgagagttg ataacacccg aagccggtgg cctaaccgca aggaaggagc 1440
tgtctaaggt gggattgatg attggggtga agtcgtaaca aggtaacc 1488
<210> 3
<211> 1370
<212> DNA
<213> Erysipelatoclostridium ramosum
<400> 3
tgcggttagg ccaccggctt cgggtgttat caactctcgt ggtgtgacgg gcggtgtgta 60
caaggcccga gaacgtattc accgcgacat gctgattcgc gattactagc gattccaact 120
tcatgtagtc gagttgcaga ctacaatccg aactgagaat ggttttatgg gttttgcttc 180
acctcgcggc ttcgcttccc tctgcaccat ccattgtagc acgtgtgtag cccaggtcat 240
aaggggcatg atgatttgac gtcatccccg ccttcctcca gcttgtcact ggcagtctcg 300
ctagagtccc caacttaatg atggtaacta acgataaggg ttgcgctcgt tgcgggactt 360
aacccaacat ctcacgacac gagctgacga caaccatgca ccacctgtat ctcatatagc 420
tatctctcca tctctggagc ctttatgagt atgtcaagac ctggtaaggt tcttcgcgtt 480
gcttcgaatt aaaccacatg ctccaccgct tgtgcgggcc cccgtcaatt cctttgagtt 540
tcattcttgc gaacgtacta ctcaggcgga gtacttattg cgttaactgc agcactgaac 600
tttgacatcc aacacttagt actcatcgtt tacggcgtgg actactaggg tatctaatcc 660
tatttgctcc ccacgctttc gggactgagc gtcagttgca ggccagatcg tcgccttcgc 720
cactggtgtt cctccatata tctacgcatt tcaccgctac acatggaatt ccacgatcct 780
ctcctgcact ctagctgcct ggtttctatg gcttactgaa gttaagcttc aggctttcac 840
cacagaccct tgctgccgcc tgctccctct ttacgcccaa taattccgga taacgcttgc 900
cacctacgta ttaccgcggc tgctggcacg tagttagccg tggctttcta ataaagtacc 960
gtcactcggc taccatttcc tgtagccgcc gttcttcctt tataacagaa gtttacaatc 1020
cgaaaacctt cttccttcac gcggcgttgc tcggtcaggg tttcccccat tgccgaaaat 1080
tccctactgc tgcctcccgt aggagtctgg gccgtgtctc agtcccagtg tggccggtca 1140
ccctctcagg tcggctacgc atcgtcgcct tggtgggccg ttaccccgcc aaccagctaa 1200
tgcgccataa gtccatcctc taccagtgct ttgaggcact tttaatacgg tcaccatgca 1260
gtgtccgtac ctatgcggtc ttagctatcg tttccaatag ttatccccct gtctagggca 1320
ggttacttat gtattactca cccgttcgcc actcgagcac aagtgctcgc 1370
<210> 4
<211> 965322
<212> DNA
<213> Erysipelatoclostridium ramosum
<400> 4
gtggcaggtc tcgcctgtgg tggattctcg aaactaagaa ttttcatcac taaaaaacat 60
aaatcgaaag gaaggatgga ttttagtaaa tagttgaaaa tagtaatcaa gcaaacacca 120
aaataggtaa agtaagaaag agcgtatggc ggatgcctag gcacagagag gcgaagaagg 180
acgcagcaaa cagcgaaatg cgacggttag cagtaagcat gcaacgatcc gtcgatgtcc 240
gaatggggga acccacctgg agtagagacc aggtatcctg aagtgaataa atagcttcag 300
agaggcgaga ctcagggaac tgaaacatct aagtacctga aggaagagaa aataaacgaa 360
tgattcccta agtagcggcg agcgaaaggg gaagagccca aaccgatctt aggatcgggg 420
ttgtaggact gtcggcaaag agcaagaaat cattataggc gaacggaatg ggaagtccgg 480
cgaaacaggg tgacagcccc gtagccgaaa tagtgaagaa gcacgagaca gcacctgagt 540
acggcgggac acgaggaatc ctgtcggaat ccaccaggac catctggtaa ggctaaatac 600
tcctctgtga ccgatagtga accagtaccg tgagggaaag gtgaaaagaa ccccgggagg 660
ggagtgaaat agaacctgaa accatatgct tacaagaagt tagagcccgt taaagggtga 720
tagcgtgcct tttgtagaat gaaccggcga gttacgatat ggagcgaggt taagcaggat 780
atgcggagcc gaagcgaaag cgagtcttaa cagggcgaaa gttgcatgtc gtagacccga 840
aaccgagtga tctagccatg accaggttga agttggggta aaacccgatg gaggaccgaa 900
ccgacccccg ttgaaacgtt ggcggatgag ttgtggctag gggtgaaatt ccaatcgaac 960
tcggagatag ctggttctcc ccgaaatagc tttagggcta gcgtcgaggt aaagtcgtgt 1020
gaaggtagag cactgaatat gtgatggccc catctcgggg tactgaacat aatcaaactc 1080
cgaatgtcac aaagatatac tcggcagtca gacagtgggt gataaggtcc attgtcaaaa 1140
gggaaacagc ccagaccatc agctaaggtc ccaaaatata tactaagtgg aaaaggatgt 1200
ggagatgtcc agacaactag gaggttggct cagaagcagc catcctttaa agagtgcgta 1260
acagctcact agtcgaatga ctctgcgccg ataatttacc ggggctaagt atattaccga 1320
agctatggat ttacgcgtaa gcgtgagtgg taggggagcg ttctatgtgc ggagaagcgg 1380
taccgtaagg agccgtggag cgcatagaag agagaatgcc ggtgtgagta gcgaaacgtg 1440
ggtgagaatc ccacgcaccg aaaacccaag gtttccagag gaaggttcgt ccgctctggg 1500
taagtcggga cctaaggcga ggccgagagg cgtagtcgat ggacaacagg tagagattcc 1560
tgtacttacg gtatgaatga tggagtgacg gagaaggcta gcggatcctg ctgatggaaa 1620
tgcaggtgca agcgaggtag ccgacagcca ggcaaatccg gctgtcgaaa ggcaaaggcg 1680
tgaggcgtat ggaaagctgc ggcaagtaca gaagtccgtg aagccagctt ccaagaaaag 1740
cttctagtga taatcataca gtaacccgta ccgaaaatgg acacacatgg gtgaggagag 1800
aatcctaagg tgagcgagag aactatagct aaggaactct gcaaaatgac tccgtaactt 1860
agggataagg agtgctcata gagatatgag ccgcagtgaa acggcccaag cgactgttta 1920
ccaaaaacac agctctatgc taagtcgaaa gacgacgtat atggggtgac gcctgcccgg 1980
tgctggaagg ttaagaggat gtgtcagcgc aagcgaagca ttgaattgaa gccccagtaa 2040
acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcagg taagttctga 2100
cccgcacgaa aggcgtaacg atttgggcgc tgtctcagct gtagactcgg tgaagtctta 2160
gtacctgtga agatgcaggt tacccgcgac tagacggaaa gaccccatgg agctttactg 2220
tagcttgata ttggactttg atgcaagatg tacaggatag gtaggagact gagagacatg 2280
cacgccagtg tgtgaggagt caatgttggg atactactct tcttgtattg gagttctaac 2340
cggatgccat ggaactggca acgggacagt gtcaggtggg cagtttgact ggggcggtcg 2400
cctcccaaag agtaacggag gcgcccaaag ataccctcag cttggatgga aatcaagcgc 2460
agagtgcaaa ggcataaggg tgtttgactg cgagacctac aagtcgagca gggacgaaag 2520
tcgggcttag tgatccggcg gtgctgaatg gaaaggccgt cgctcaacgg ataaaaagct 2580
accctgggga taacaggctg atctccccca agagttcaca tcgacgggga ggtttggcac 2640
ctcgatgtcg gctcatcgca tcctggagct gaagtcggtt ccaagggttg ggctgttcgc 2700
ccattaaagc ggtacgcgag ctgggttcag aacgtcgtga gacagttcgg tccctatctg 2760
tcgtgggcgt aggaagtttg agaagatctg tcctcagtac gagaggaccg ggatggacat 2820
atcaatggtg caccagttgt cacgccagtg gcacagctgg gtagctaaat atggaaggga 2880
taaacgctga aggcatctaa gtgtgaaacc cacttcaaga tgagacttcc cattacgcaa 2940
gtaagtaaga ccccttaaag acgataaggt tgataggtca ggagtgtaag catggcgaca 3000
tgttcagcgg actgatacta ataggtcgag gacttaacct agagaaaaag ggttaaggct 3060
tgaaactgaa agaagacaaa gtggaagaca aaagacgcaa gaaaactatt atctagtttt 3120
gagtgattct cgaaaggaat tgcttagaaa agaagatctg gtagcgatag catgatggac 3180
acacctgttc ccataccgaa cacagaagtt aagcatcata acggcgaaga tagtaccaag 3240
gtgcgacaat agcaagctgc cggttctttt tttatttacg gatacctctg cgtatccttt 3300
ttttatttta tatccggctt taataatgaa ttctaagatg ggaatattta gaaaaaaaga 3360
aggtcacttt atttgacctt cgatttttat gttttatatt tcaactgctt ctttaactaa 3420
tgcaactact tcttccatag ttccacagtt aatagcttta gcagctaatt cattcatttc 3480
agattttttc attgatctga ttaactttct ttgagaaaga atagatgtag cagacataga 3540
gaattcatct agtcctaaac cgattagtag tggtgcagca attgcttctc cagccatttc 3600
tccacacata cctgtccatt taccttcggc atgggctgaa tcaattacat gtttaactaa 3660
acgtaagatt gatgggtgga atggttgata taaataagaa accccagatg acattctatc 3720
agcagcaaat gtgtattgaa ctaaatcgtt tgtaccaatt gagaagaaat caacttcttt 3780
ggcaaattga tcagctaaca ctgctgcagc tggaatttca atcatgatac ctacttgtaa 3840
tgtatcagat acttcgattc cttcactaat taatttttct ttttcttcca ttaagattcc 3900
tttagctttt ctaaattcat ctaaagtagc aatcattggg aacataattc ttaaatcacc 3960
atatactgaa gctctaagta atgctcttaa ttgaactcta aagatgtctt ctctttggaa 4020
acataaacga accgctctaa ctcctaagaa tggattcatc tctttaggta aatcaattgc 4080
ttcgatttct ttatctccac caatatctaa agtacgaaca acagcaggtt ttccttctaa 4140
tccttcaaga acctctttat aaacattgaa ttgttcttct tcagttggta attgagcaga 4200
ttccatatat aagaattcag ttctgaataa cccaactcct tcaccaccat tgtctagtac 4260
accttggatg tcttttggag atccaatatt agcaactagt tcgacgtgat gatcatctag 4320
agtaacagat ttttcatttt tcattttctt taattcttcc ttgtatgcga tgaatgcttc 4380
acgtttagct tgatattctt taatttcatc atcactagga ttaataatta caataccagc 4440
ttcaccatct aaaacaacca tatcagcatc attagtttca tcagttattg ttttacaaga 4500
aacaaccgca ggaatttcta atgaacgcgc catgattgct gagtgagaag ttctaccacc 4560
aatattagta gcaaatcctc taactaagtt tttatttaat tgcgcagtat cagatggagt 4620
taagtcatca gcaataataa caacttcttc atcgattaaa gcaggatttg gcaatgactt 4680
acctagtaag ttagctaata aacgacgaga tacgtccttg atatcagccg ctctttctct 4740
aaaataatca tcatccatac tttcaaacat tgcaataaaa gtattagcaa cttcatctag 4800
agcagcatca gcgttaatct tttcatttct gattttatcc tctacttgag tttttaattc 4860
aggatcttgt aatactaatg catgagcatc aaatacagca gcttcttctg cagataaatt 4920
tttagcagca gcttccttaa ttgattctaa ttcttttgca gtttgtgaca ttgcatcgtc 4980
aaattttttg atttctgcct cagcatcttc tactgttact tttgtcactg ttaaatccgg 5040
cattactagt ttgtatgctt tagcaatcgc gataccacta gatgccccaa taccttttat 5100
catattaaaa acacctccat atacattcct attttacctt atttttagca aaaaataaag 5160
aaatatcgaa ctgtgactag gtattttcgc gttatgaaaa aagggctttc aaaagggact 5220
tacaaattaa tagactttga caaaaaatac atgactcgtt tttttcgagt tttgaaaaat 5280
gattgatatt tccggccttt aacttgaagt tttaaggtaa aaatagtatc atataagtgg 5340
agggacacaa aatgaaatta attatagttg aaaattatga agaagcaagc attgaagctg 5400
caaaagttat gttagaagtt gttaaaaaca atccaactgc taatttggga ttggctacgg 5460
gatctacacc aatcagaatg tatgaattga tgatcgaaga tcacaagaag aacgggactt 5520
cttataaaga tatcaaatca tttaacttag atgaatattt tggattagaa gctactcatc 5580
cacaaagtta tcattatttt atgaataaac atttattctc tggaattgac attaatcctg 5640
aaaatgtaca tgtaccaaat ggtgctggag atattcaagt aagttgtgat gattacaata 5700
aattattagc tgaaaatcct atcgatatcc aattgttagg aattggttca aatggacata 5760
ttggttttaa tgaaccagga acttcttttg attcagtaac tcatatgatt gaattaaaag 5820
aaagtacacg tcaagataat gcccgtttat tctttgatgg gaaaattgat gaagtaccta 5880
ctcatgcgat tactatggga attttaaata ttttacaagc taaaaaagta ttattagttg 5940
cgtgtggtga aaataaagct caaccaatca aagtattggt tgaaggtgaa aaaactacag 6000
acgtaccagc aagtgcactt caagatcata atgatgttgt tgtaattgtt gataaagcag 6060
ctgctagttt attaactaaa taataaaagg aaagatttat aaatctttcc ttttttaaaa 6120
cctttttttt acctttaaag aaatgtgttt aatttgttta cgtaagataa ataacgtata 6180
attattatat gggggtacta aatatgacaa aaaatttatt taaagaagta gcgatgaatg 6240
aaacaaatcc aaactactca aaagcaatat caagacttga accattgtat caaagaagta 6300
atgatctacg tagtgagttt ggtcgtgatt atacgagaat tatcttttct caggcatacc 6360
gacgtttaaa acataagaca caggtgtttt ttgcagttaa ggatgatcat gtttgtacac 6420
gtagtgaaca tgttaactta gttgaatctg taagttatac aattgcaaat tacttaggtt 6480
tgaatactga attaactaaa gcaatagcag taggccatga tttaggacat gccccatttg 6540
gtcatggtgg tgaacgtatt attaacgagc ttgctaaaat acatgggctc gattcttttt 6600
ggcatgagcg caatagtctt catctcattg atgaaataga aacattagaa gataatgaac 6660
atcatcgcca taatttaaat ttgacatatg ctattcgtga tggaattatt tctcattgtg 6720
gagaaatgaa tcaaatgagt attaaaaagc gagatgagta tattgattta caaaattata 6780
ctagcccagg acaatacagt ccttatactt gggaaggatg tgttgtaaaa atggcagata 6840
agattgccta tttagcacgt gatattgaag acgctttacg tctcaaggta ctaaaagaga 6900
ataaagttga agtcttgaaa gcttcgctca ataatattac tagtgaatat cattttacag 6960
caatcaataa tggaactgtc gttaattatt ttattcaaga tgtatgcagt catagtaatc 7020
caagcgatgg aatttcatta tcaaaagaag cttttgaaat aatgaaaaca attatgaagt 7080
ttaattatca aaatatatat ttaattgata gagtacaaat tcatactaat tatgttaaat 7140
tgattttaaa ttctattttt gatttcttta ttaaatacga tttaatggct cgagatagta 7200
atactaatat tattgatgaa atttctaagg ataaagatca atttccccat gcaatcaatg 7260
gatttatcca ttggcttgaa aaatatagtg tgatgaatgg agcaaaacgt gattcgcttt 7320
atcaaaataa agttatttat gattttatta atgatgataa agcaattatt aaaagcattt 7380
tagattattt atcaggaatg tcagatgcct atattattca aatatttaat gagcttattt 7440
cattttaatc cattgaagaa attcaatgga tttattattt ttacttaaat tattagaata 7500
gatgtggtaa actaatcatt attagggagg tttaaatatg cctattaaaa taccaaatga 7560
tttaccagca agtaaaatat taaaagaaga aaatatcttt gtgatggatg aaaatcgtgc 7620
tttagctcaa caaattaggc cattgcaatt attaatttta aatattatgc cgactaaagt 7680
agtaactgaa acacagcttt taaggatgct gtcgaataca ccacttcaaa tcgaggtaga 7740
ctggattcat atggccagtc atgaatctaa aaacacacct caagaacact tattagcttt 7800
ttataagaca tttgaggaaa taaaagataa taaatatgat ggtttgatta ttactggagc 7860
accggtggaa aaacttaggt ttgaagatgt tgattactgg ttagagatgg aaaagatttt 7920
agaatggtca aaaactcatg tatttagctc attttttatt tgttgggctt ctcaagcagc 7980
attgcattat ttttatggta ttgagaaaca tgaattaaaa gaaaaactga caggtgttta 8040
ttttcatcat actaatgttg ataaaatgaa gcgaaagata cttagaggct ttgattatca 8100
attttatgct cctcattcac gttatacaac aattatggca gaagatatag caacgatttc 8160
tagtcttgat attttagctg ctagcgatga agcaggggtt tatttgattg cagaaaaaga 8220
tggctcacgt ttttttgtaa ctggtcatcc tgagtatgat cctgatacat tagataaaga 8280
atataatcgt gatctggcaa tttctgatca agctactatg cctaaaaatt attataaaaa 8340
tgatgatatg cacaatgaaa ttttagtaaa atggcgttct catgcttatt tattatttag 8400
taattggtta aattattacg tttatcaaga aactccatat gatttaaatg agttagaaag 8460
tttaaaacta ggtaaataat gtaatattgt atttacgata agtttaaaag ttgaagaaat 8520
aaatcttgct caaattaagt aaatcttcta agttggacca gcaaatgata tgtatcaaga 8580
attctagaca catatcattt ttggtccaat ttttagaatc ggtacaattt gagtaatcag 8640
taaatttata tataatttct aaataatgca gtagaattaa gtttctattt cttttaagag 8700
tttactttga gtttgtctgt atcttagtgg tgtaaggccc attgtttttt tgaatatttt 8760
atcaaaatat tcaatattat taaagccaca ttcaaaagct atatttagaa ttgataattc 8820
agtagataaa aggagttcta ttgccttatc tatttttttt atttaaatat tggctaggag 8880
tcatatttaa atattcatga aattttttaa ttgtatattg tttagaatat ggtgagatga 8940
taaaaatatc ttttgtttct ttaattttat ttaaatcttg tatttctaat aataatgatt 9000
taaaccaatt tggatatata ttcgtatctt ttgattgatg atagattaat tcttttatca 9060
tttgatataa gaacaattct atatctttat ttaactcata ataagaatcg ttgagattga 9120
tatcattata gtaattaatt agttttctag atttttcatc agataagtgt cctattacag 9180
tatcattaat taaatgaaaa cctccaaata tagtctgaac tctattcata attttgtcag 9240
aaaaagctaa attgatatat tttaaggaaa tattttcatt aatagtaaca agttcatgaa 9300
aaatattttt tttcattaaa ataatgttat ttcataatat gtctgataat gttttcctac 9360
ttcagatttt tttctttttc ggtgttgcca gtgaatatct ttgctgttat tgatgatttc 9420
tagacttagt tcttgcataa agcacctcca ttatttttat tatattataa ttttgattta 9480
aataaaatta aaaataaagt tagaaaaata agataaaatg aatgctttgt ttaataaagt 9540
ttaaaaagcg aatatatgtt aagtatgata taccttgtta tgatactctt tatatgaaaa 9600
ggaggtagac aaatgaatga aattcaatat ttaaaagagt ttacgagatt gtataaagaa 9660
aatagtcatg ataaatacaa tcgggaagta gaatgccatt tctttatgca caaggaaaat 9720
cgtacaaaaa taacgagcga tgattatttc ttatcatgtt ttcctagtgc aatttgtggt 9780
tttggatcaa gaaatactaa ctttatttac aattgcaaat tagaacgatt agcaaaatta 9840
atcgaaggta cacatgatgt tgaaaaagaa gaattagaag aattgtatac gttttgggct 9900
gatgagaatg ataaagaacg tcttagaaga tattatccaa atgatataaa agaattaatg 9960
ccatatgatg attttgaaaa tgattattat acagcgtatc ctttatatag attaggagga 10020
gcttatcttg attttgaaaa attatttgat ttaggaatag atggattgat tcatgaaatt 10080
gattctcaac cactcaatag ttttttaaga gcttgtaaga aatcgcttat ttacttaaaa 10140
gaattaataa aactgtatcg tgatgatgcc atggacatta atcctgaatt ggcttatacg 10200
ttaaatgaat tacttgaaca tagaccacaa aatatgaaag aagcgattca attaatgtgg 10260
atttatgtag gcgttagtga aattagaaac tatggaagaa tggataatca attagcacgt 10320
tttttagatg atgaacaaga tgcatataag aatattgcag aatatttcaa ggtaattaga 10380
caacgaaata cgatttacaa tggtcgtatt attttaggtg gagagggtcg tcatgatctt 10440
gaaaaagcaa acaagatatg cagtatagct cttaaagtta tgaaagattt acatttaact 10500
gaaccacaat taacacttag gtggtcaaaa gatatgcctg atagtatttt tgataatgcg 10560
attgattgta tagaaagtgg ttgtagttat ccattattat acaatgacac ggttaatatt 10620
aaaaatgtca aagaatcaat gaatgtatca tataaagaag cagttgatta tgttcctctt 10680
ggttgtggtg aatatgtttt ggatcataaa agcattggtt cacctaatgg aatcattaat 10740
ttagctaagg tattagaggg gctggttaat gatggaaaat gtatgaattt agtagttgga 10800
gcaactggca aagacagaaa taatactatc ggaggacata aggcatgagt gctattattc 10860
atttaaagca ttatatttca aaaaagcatc tacctacgtc tttagagaaa aatgttcagt 10920
acagtttcct tgtatatgaa agttaaaacg taaagaacta ttaaaatatg tgtggtaata 10980
ttgagtggtg cttttaattc cctacttgcc acatatccaa caaaatattt aggaatatct 11040
attgtggaat gtgttatttc caatacaata ctattcgcta aaattgacat atcttcgtca 11100
ataatatgat attttaaaga aatatctggt atgttaaaat gttataaaat aatagaaata 11160
tttttatact ctgttggtgt cattccgtat gctttcttga aattacgaga aaatatttca 11220
tggtatcatc atagaaaacg aggaatacag tataactgaa aacgctaatg ttgtgttgac 11280
gaatgaaaat atcaagaaaa tgctgaaaaa aatatcagtc aaataaataa agcaatataa 11340
gcataacggt tgacttattc caaaccaaca aaaaaagtga gtagcgtatt agatattttt 11400
ctcattaaat ttagagttat tgggagtgaa tagatttcta ggtttagtga tcgtgtttta 11460
acggtaagac ggaaaccgtt aatactatta gaatttccaa tatcaatatg tatacaatag 11520
tattctatgc tatactaaaa atgtgaggaa ggttaaaaca atgaaagaaa agattttaaa 11580
gaattgtaaa aaatactggt atgttatagc atttatcatt gtaggcttta tcgttttaaa 11640
taaagagcca gattatcttg tattgaaaaa aaatactttt aaagttgaac ttggtacacc 11700
attcaatata aaacctgaaa catatttaaa tacagaaaaa ttagataccg atgtaaaaaa 11760
ggatgtattg gaaaacgcaa aggtaactgt tgataaagat ttgaataata ttgaaaattt 11820
ttgtttagat gttggaaaat ataaagttac cgtttcatat aaaaacgaaa aagaaacttt 11880
tacttataaa gttgaagata ctaccgcccc agtaattaca ggtgcagaaa gtattgatat 11940
agtacaaagt actgatttaa gtacttatga ttttaaagtt ctttatacaa ttgatgattt 12000
atctcaaaca gatgttaagt atgatactag tgcaattgat gtaaatacaa ttggtgctta 12060
tactttaaaa attatttcag aagacaatta tggaaataaa tgtgataaag aagtagctat 12120
aaatgttgtt gctccattga gtgctgatga agtaattgtt gaggaaacag tatcaaacgc 12180
tgatggtaca acaactacaa agattgtaac tagaaagaaa accgaagcac agagtggtga 12240
ttttcgcata gttacttcgg gtgatacatc aaaatcaagt aataatagtt cttattcatc 12300
ttctagtagt tcatctaaca gtatttcaac tattaaacca agtggtagta catcatcaaa 12360
tagttcatct aataataatt ctagtgctgc taagcctaat aatggtaatt taataattga 12420
ttaaaataaa ttaagcaatt ttttacagtt gctttttttg ttgaataaaa atgtaattca 12480
aaatatttag ctttatttga tagatcagta aagtatccca attacaggaa tggaaaagaa 12540
aaatggtatt tgaaatttgg gtattggaga gtattagatg gtgcaaattc ttggaactat 12600
agactttttt attgattaga acattcaaaa tagtaagtgg atttgacgct ttggtgcccg 12660
aattttccat agtgaaataa aacgatatgg acaaatataa agaaatgata gagaaattcg 12720
tattgagtgc tataatttta gcaaacaaat ttgaagttgt ggtgggatgg gcagtatggg 12780
cggatttaaa ccaactattg gtaaatggta tgattataaa aactacgata tagatgagcc 12840
acagtggaga cgtcttttga atactgctga aaagcttgaa aatgaatttg gagacttgtt 12900
tgtatatgaa agagatgggt cgattggcta cggtcttgag attatttcca gtccaatgac 12960
aaaaggatat tatgaaaaaa tatcaataag tttaaaaacc tgttaaatat ttttaatgag 13020
tttcactatg tttctacaaa aggaaataaa tgtggttcac acatttattt caatagaaaa 13080
acactaggtt ttaattctaa agaatacagt tctctattaa gtaatcttaa taataatata 13140
agaaaagcag aagaagtaga ccacaaaaga gcaaataaaa ccattgaaaa tgtggttgct 13200
gttatggaat tatatcgaga agaattaatc aaaatcagtg gacgaaataa aagcagttta 13260
cgctggtgtc agtttgaaac atcaaatgga tatgatatag aagttataaa aaaagttgca 13320
aaagataaaa ttaaaagcga tagaaatcgt cacaatagat acaaggttgt taatactaca 13380
aatgaaaaaa ctgttgagat tagattatgt cgaggaacgc tgttatggga atcttttaat 13440
acacgtatca atttaatgta taatattgta aatgtatcta gaaactatca aggcttgatt 13500
aatttggaaa aattaattgt atataaaaat aatgataaaa caatacaaat gatgaaaaat 13560
tatattgaga ataatgatat agaaaataga aaagttgata taaaggaagt gaaaaaaact 13620
atcattaatg cctaataata gtttaagacc atcaagtttt atgtttggca aataaatata 13680
gatagacgtt aattaaaaca attaattcat tttattgttt tgatttttta catgaaatag 13740
gttctagatg tctgggaaca ttgcttactc acccgaagaa aataaggaat gcattcctta 13800
attaaagaag aaagaggcaa tgaatatgtg tataattatt gtaaaaaata gcagaatgga 13860
cttaccggat aaagagattt taaaaagatg ttggaataaa aatcctcatg gtgcagggtt 13920
catgtacaat tataatgatg tagttattat taaaaaaggt tttatgtttt tgatgatttt 13980
tatgaaaatt tgcaaataaa tgataagctc tataaattga aaaatcaaag tgttgtattt 14040
cattttagaa tatcaacaag tggtaaaatt gatgagggaa attgtcatcc atacccgctg 14100
actgatgaca gtatatacct tagaaaaaca aatttacgtt gttctattgg aattgcacac 14160
aatgggataa ttcaaaaata taaccgtaaa gatagtgtgt taaatgatac ataactgttt 14220
ataaaaaaca taatttatga tttgattaca aattaaaaag aaaattgatg aagagaaagt 14280
tacagtttct aaatgcgaag agcagctgaa gaaatcaaaa atcagcctat ctaactttga 14340
aaaggataaa aaggcactgc tgagactaaa gaaaaaagta gatgatttta atagaaaaat 14400
cagcgaaagt ctatcggaat ttgactgaat ttaatgtctt tgaacatttc aaaaaacacc 14460
ctcaacttct gattatcatg caacatatga attttttgtt attttgttat aatgttttta 14520
ttaatcatat tattgtgcta aaattgataa taacttgata caatacaaac aaaaaagagt 14580
gtctattgac catagatcac tctaagagac catctaattc taaaaagcag ttagaatcga 14640
tgaacaatat atatatacta tatattgatt gatttatata tgttttaaaa aatataagtt 14700
aaataataac ttgtatttag tatatcatat taaaaaatca attcaactat aatagcatcg 14760
tttttaaact tcgctttagc tagattaaat ggttatatag aaacattttt tggaataacc 14820
ttttaactaa ctgttgttcg aagtgaaaaa aatggtgccg gagctaagaa tcgaacttaa 14880
atttcatgat taccattcat gcgttctgcc attgaactac accggcattg gtgcagacag 14940
cgagatttga actcgcacga gctattgctc actaccccct caagatagcg cgtataccag 15000
tttcgccatg tctgcaagta ttaatagttt atcaaattat tgcagaaaaa taaagcctag 15060
aacgtaaagt tctagacttt tttctttaat ctgccttaat caagttgtat aaagcatgac 15120
aataaatttc tgttgctttc aataacgaat cgattttgat attttcatta ttaccatgaa 15180
ttaaattatc ttcacccaaa aattcagctc caaaagcaac acagtttggc attgacttag 15240
cataagtccc gccaccaatt gcttgaggtt tgttaactgt atctccagtt acactaacat 15300
aagcttcatg caaattagta attaacttag aattaggatc gatatataga gccttgccca 15360
aatcatgagt ttctctgaat tcatagtttg cacaagcatg tttaaatttt gtaaccattg 15420
catcaaaatc catgtcatga gggcaacgta agtcgagaac gattttaact tcttctttat 15480
aataagatat aactcctaaa ttaagagtaa gaggacccat taaaccggta tggtcaattc 15540
ctaatttttt accatgacag tcatctaaat attcaagaac aaaatcaaca actttgttat 15600
caacgacagt tgctaaatat ttgcataaat atacaacagc attaatgccc tcttcaggag 15660
tacttgcgtg tgctgatttc cctttaagaa ttaatttagt atgatttcct tcctcttcaa 15720
tatccccagt taaattatta gtatttagga atttcttata agattcagta tattgtttgt 15780
aattcccttc aattactgct tcgcaagttt ctggaacaat atttggacga cttcctgcac 15840
ataaatagat taatccacct ttttcaacat gtcctgtgat ttcaaaacca caacctgctt 15900
tttcaccata aacaacagga aaagcagcat caggagtaaa tcccatttta ggataaggca 15960
tctttgtgaa ataatatttt acacaattac tacctaattc ttcattgcat ccaaagataa 16020
ccctagtttt catttttgta ggaatattta aagaattaat gatctttgca gcataataac 16080
cagccattaa tggtccttta tcatctgcga ctccacgtcc gtaaagcttt ccttctttag 16140
taataacttc aaatggatca ctatcccatc caaccttgtt tacaggaact acatcaagat 16200
ggcccaaaat tccaaaagtt tcatcaccag ttccaatatc aatatgtcca gcatgtccat 16260
caacatcctg cacttcaaag ccatcacgtc gaccaatttc taacattgca tctaaagctc 16320
ggcgattggc tgcgccatag ggagcaaact cagcaacggt actatcatct tgagttgaag 16380
ggatggcaca taacattttt atatcatcaa tcatttgatc ttttattttt aaaacttccg 16440
ctttaaaatc aatcatatta tcacctcgtc atcaattata acactattag ttataatatt 16500
taaacaattt tagtaataat agtgttatga tatatataat aatcggaggt atgacatgaa 16560
taatgtaaga tttcacataa cagtcaaagg aattgtcgta ttaaataacc agattctttt 16620
aatgaaacga attcgaccat caagtgatgg tcttggttat tgggagttac caggtggtgg 16680
gttggaatat ggtgaaacac ctaatcaagc attaatcaga gaattacaag aggaaaccgg 16740
attagatatt atcataatca aaccagctta tactttcact aaaattagaa aagattatca 16800
aaccgtagga atcggatatt tgtgtattcc caagaatgat catgtccgtt tatcgcatga 16860
gcatagtgat tatcgctttg tgagtataca agaggcaaaa gaactgttaa atccagaaat 16920
ttataatgat ataattttta caattgaaga atattatcag aacgttcatg atatccagtg 16980
ataatatttt aaatttgatt atagtcatcc aaaataacgg tcttgaaatt caagactttt 17040
tcttttatca gttgatattt tatttatttg aagtaaaata aggtagttga aaacaaatag 17100
aattaaggag ttattatgaa cgaagaaatt attgcaatag catcaaaaga attagaaata 17160
actaaaaaac aaatcaatgc tgttttatca ttattagaac agggaaatac tgtgcctttt 17220
attgctcgtt atcgtaaaga agcaacagga gggttagatg aagatcaaat cagaaatatt 17280
gataaatatt atcaatatca agttagttta ttaaaacgaa aagaagatgt aattcgttta 17340
attgaagaaa aagggatgtt aacagatcaa ctaagggctg atattttaaa agcaacaaag 17400
ttaaatgaag tagaagacct ttatcgtcct tataaagaaa aaagaaaaac aaaggctact 17460
gaggctaaag ctaaaggttt agaaccatta agtaagtgga ttttatcact gccaagggga 17520
gaacttaaag aagaagcaaa aaaatattta aatgataaag ttgagactgt agaagaagca 17580
attcagggag ctttagatat tattgcagaa gtaattagtg atgatattaa atatcgtaaa 17640
tttgttaaag atataatata taaatctggt acgattgaaa caaaagtaaa aaagaagaat 17700
cctgatgaaa ataaagtata tgaaatgtac tatgattatc acgaacgagt taatcgaatt 17760
gtatcacacc gtattttagc gattaatcgt gccgaaaatg aaaaagttat tactgttaat 17820
attgttttag ataaagaatt tttaattcaa tatattaatc gtggagtgac tagaaatcgt 17880
aatagcagtg ttaatgaata tttattgaaa gctgtagaag acagtttaaa tcgtttatta 17940
ttgccatcga ttgaacgcga agtgcgcaat gaattaactg aaaaagccag cgagcaggcc 18000
ttaaaagtat tttcaatcaa tttagaaaag ttattaatgc aggcaccttt aaaagataaa 18060
atggttttgg gtctggatcc tgcttatcgg acaggatgta aattagctgt tgttgatcag 18120
accggaaaag tattgaagat tgataaagta tttattacta ttccaaaaga taattatgat 18180
aaagaaaaaa gaattttatt aaatttgatt aaaaaatata aaattgaaat tattgcgatt 18240
ggtaatggta ctgcaagtcg tgaaagtgaa gcttttattt ctcaattaat caaagataat 18300
aatttagatg ttgattatgc aattatttct gaagctggag catcagtata ttcagcaagt 18360
aaattagcta aagaggagtt tccagattat caggtagaag aaagatcagc ggtttcaatt 18420
gcacgacgtc ttcaagatcc attagcagaa ttagtaaaga ttgagccaaa agcaattagt 18480
gtcggacaat atcaacatga tattgctcaa aaacaattag aagaacaatt agattttgtt 18540
gttgaaaaag cggtaaataa tgttggagtt gatatcaata ctgcttcagt atcattatta 18600
caatatgttg ctgggttaaa tagcggagtg gccaaaaata ttattaaata tcgtgatgaa 18660
aatggtaaat ttacaaatcg taaagaaatt atgaatgtta gtaaattagg tgcaaaaaca 18720
tatcagcagg caatcggatt tttgcgaatt cctggagcta atgatccatt tgatgcaaca 18780
gcaattcatc cggaaaacta tcaacaagca aaaaaattac ttaaattaat agatgctgat 18840
gctagtttat taggaacaaa tgaaattgct gataaattat caaatattaa caaagaggaa 18900
gtaatgaatg aactaaatat cgacaattat acgttagatg atattattga tagttttata 18960
aagccaaatc gctcaccccg tgatgcatat gcaacaccat tattaaagaa agatatttta 19020
aaaattgaag atttaaaacc cggtatgcaa ctagaaggaa cagttaggaa tgttgttgat 19080
tttggagctt ttgtcgatat tgggttaaaa aatgatggat tagtccatat ttcgaagatt 19140
tctcatgaaa gaattaagca tcctttggat aaactaagta taggtgatat tgttgaagtc 19200
tatgtcattg atgtagatgt caacaaacat cgtgttggat taagtatgat taaataaagg 19260
atgagttgat gaaaaagttt ctagttggaa tagttattat aataattgcc agtattggct 19320
ttaatttaaa acctgataaa agagatcaag ctgttgtggt tcaagaagag cctgtagtta 19380
aaaaagaaga agttattact tataaagaac tattagaata tcttgatatt tttaaaacag 19440
gagatattat taatattgaa aatactaatt atttaagttc atatgctatt ccaggaagat 19500
ggaaacatac tattttctat ctaggaacat atcagcagtt tagtcaggtt tttacacctg 19560
aagataaata ttatgaggaa attaataaac attataagaa tcaagatgag gttttagtac 19620
tcgacagtaa ttctacgggt gttaaaatac ggacatttga tcaaatggct aatcttaaag 19680
aagaatcgta tttaaaagca ctttccggct atcgttttaa tgaggatgat aattttatta 19740
agacatattt aagtcgggcg ttagattatt tgggaacacc gtatgattac agcatgacaa 19800
cttatgatga taaagcttta tattgtagtg aattagttta ttatgcacta ctagctaata 19860
atatagaagt gactaaaacg agcagtattg tcgaacatgt tgtaattacc ccaacagatt 19920
taagtgattt tttagaaaca ttagaagata ttgaccatgt atatttgctt gaaaaagaag 19980
ataattggat aaatgatgcg ataaatgact agtttttgct ttattttact tgtattccta 20040
ctttaatact agtattatat aaacgaggtg aacatcatga aaatttcaac caaagggcgt 20100
tatgcaatta gagttatcct tgatattgcg atgcacgatg atggtaaata tattccactg 20160
aaagatattg ctaaaagaca agatctgacg gttaagtatt tagaacaaat aatttcatta 20220
ctaaataaag cgggctattt acaaagtctt cgtggtaatg ctggaggtta tcgcttatca 20280
aaaaaacctg aagaatgtat aattggtgat attctaagaa ttacagaagg tgatttagct 20340
ccaattccct gcttgaaaga tgaaattaat aattgcagtc gtgccaatga atgtattaca 20400
ttaccgtttt ggcaaggatt agataaagtg attaaagact atgttgaaag tgtaactatt 20460
caagatttaa tcgatcatgc aaatatgcaa gtgaataatt attcaatata aaaagccgta 20520
aggctttttt attatataac tattgacata aatttgctct caaggtataa tcatattaat 20580
ccgataggaa aagagggaac tataatgaat gagctaattt tttataaaaa tagaggctgt 20640
tgttaataat agatttgatt agataaagaa aatggaggaa atagtaatga cttataataa 20700
tcatattagt gaattagtag gaaatacccc aattttaaaa ttaaacaatt atgttacaaa 20760
aaatcaatta aaagcaaata tttttgctaa actagaatat tttaatcccg caggaagtgt 20820
taaggatcga attgctaaag ccatgttatt taaagctaaa gaagatggaa ttttaaaacc 20880
ggattctgta atcattgaac caacgagcgg taatactgga attggattag cttctctagg 20940
aacatcctta ggacaccaag taattttaac tatgccagag acaatgtcga ttgaacggcg 21000
aaatttatta aaagcctatg gagctaaagt agttttaact ccaggaggac taggcatgaa 21060
gggagcaatt gccaaagcag aagaattggc caaagaatac aaaaatgcgt ttattcctag 21120
tcaatttgaa aatcaagcaa atccaaatgc acattatcta acaacaggtc ctgaaatcta 21180
ccagcagcta gaaggtaaga tagatatctt tgtcgctggt gttggaactg gaggaacaat 21240
tagtggaatt ggaaaatatt taaaagaaaa aaatcctagt attaaggttg tagcaattga 21300
acctgctgcc tcaccagttt tatctaaagg aactccagga ccacatgcaa ttcaagggat 21360
tggtgcaggt tttgttccta ataccttaaa tactgatatt tatgatgaaa ttattacaat 21420
tgaaaatgaa gcagcctttg ctactagccg tgcaattgct agagaagaag gagtgttagt 21480
aggtatttct tctggtgcag cactttatgg agcaacagta ttagcgaaaa gaattgaaaa 21540
tgctggcaaa aacattgttg tgttgttacc agatactggt gaacgctatt tatcaactgc 21600
attagttgaa caagattaat aatatggata ctgtctttag ggacagtatc tttttctaac 21660
tacaaaaata atttttaatt ataattatat tttaaaagtc tatcataaaa atatgagtgt 21720
ttgttatgca actaggataa acaactaata atttaaagtt taataatgag attcactatt 21780
taaaaatata aatagacggg aagaagagca gagaaagatg attagttgta atgaggtgat 21840
tgtagtcaat atcaatatta gccaaaaaga ttgtccaaaa tatctttaaa ttatggacaa 21900
tctttttttt gttatagtat acaaaaaagt acttggaata tttgtaattg atatcttaat 21960
aaacagaaat tatatcattg aggtgatatg ataagttgtc ttgtatggac gagcttaaac 22020
aaaaaagttc agttaaaatc ctgttgattt gaaaaagtaa ttagtacagt taaaaagaat 22080
aaatcaaaat taaagttata gaggataatg tattggttat tataataata agatatcatt 22140
ctacattctc actggacatt taggaaaata aaaaacatag tctgaagagc attgtgtaaa 22200
atacttttaa tgctactcaa ttgctatgcc ttttattcaa ataatgttgt tgataagtaa 22260
cgttctccag tatctggcag tagaacaacg atgtttttat ttttatctgt tattttagtt 22320
gctccatgca gggcagctcc agcagttatt ccaactagta ggccttcttt ttttgctaat 22380
attcgtgcag cctcataagc atcatccgta gaaactgtta tcacttcgtc gactagatcc 22440
aaatcgagaa ttttaggaat aaaatttgct ccaattcctt gcaaatcatg cgctccagct 22500
tttcctttag tgattaatgg agaatctttt ggttcgattc caataatttt aatatcagga 22560
tatttctttt ttaatatccg agcaattcct gtaattgtcc ctccagtacc aattccggca 22620
acaaaatagt caatattatc atcaaaatca tcaataattt ctaatgccgt tgtttcttca 22680
tgggctaagg gattacttgg attaacaaat tgacctggaa tatagctatt ttcaatctta 22740
ttagcaagtt cgttagcttt atcgactgat ccttgcattc ctttttctcc agccgttaat 22800
acgattttag ctccgtaagc ttttaataat ttttgacgtt ctaatgacat agtttcaggc 22860
atcgtcaaaa ttaattcatt accatagata gcacacgcaa ttgctagacc aatgccagta 22920
ttaccactag taggttcaat aatcgtagtt tttttattga ttagttgatc ctcataagcc 22980
tgttcaatta atttaagacc aacacgatct ttaacactgc caccaggatt aaagaattct 23040
actttggcaa atattttgtt gtttacttca catgcttttt taaagcggtc aatttgaatt 23100
aatggagttt ttccaattgt atccaaaaca ctttttttaa tagtcatatt aaattcacat 23160
cctttttctt tttatatcac atattgaagt gtaagtgata taaaaattat aattttattt 23220
agttgtcttt attaaaatag taatttataa tacttttaaa ggggactgtt tatgaaggat 23280
tataaatatt tagaagttta tcaaactatt gttgatgata ttgaaaatgg ttatttaaaa 23340
tataatgata aaataccatc aattcgtaaa atggcaaaac aattagatgt aagcagaact 23400
acggttgaaa gtgcatattt acaattatta gtcgagggtt atatttacgc aaaagaaaaa 23460
gtaggatatt atgtggatgt gcaatttagt aatcaaatta aaaataaaaa gaatccaaaa 23520
gtaattacaa aaattgatag tcaccattat cgatatgatt ttagtggacg tcttgttgat 23580
gtggaaagct ttaatttaga tacttggaaa aagtatatta aaaaagcatt aaatcaaagt 23640
gaagatttaa tgagttatgg agaaccatta ggggaaatgc ctttaagagt agctttgcag 23700
gaatatagcc atgaataccg tggagttcgg catcctgtaa ataattatat tattggtgcg 23760
ggatttcaaa ttcttcttta tcatgtttgt agtctttttg gtaaagataa tatagtcgga 23820
attgaggaag gaggattcaa acaggcagag gccgtttttc atgattgtca tatgcaggta 23880
gttaagttac cggttgatga agaaggcatt actttagagg gattaagaca agctaattta 23940
aaattattat atttaaatag ttcttctgga gggtatcatg gtcatcctat caaacaacag 24000
cgtcgtttag aaatcattga atatgcgaga gctaatcaag tctatattat tgaagatgat 24060
cataatggag aattgaaatt taacactaaa ccaatcgatg caatgtcaaa actagacaat 24120
gaccacatta tttacattgg ttcattttca aaattattac taccttcaat aagaattagt 24180
tatatggcat taccaaacca attagttcag ttattttatg aaaagtctcg agattatcat 24240
cagactgcat caaaattaga acagctggct ttagctatgt atgttgaaga tggacagtta 24300
gcacgacatt taaagcgatt aagaaaacat taccgcaata aaagtactca tttgttacaa 24360
aagcttcgaa ctacttttcc tcaacataaa ttcgaattat atgaaacctc attaaaaatc 24420
acaatggcaa ttaaggctga tttggttgat caatatattg ctttagcaaa acaaaatgat 24480
attttagtta ataaaaatag taataatcag attactttat ctttttcagg aatcttagat 24540
caagatattg atgaagcagt tgatagatta aaagaaattt ggataaatta aaaacagtgc 24600
attgcactgt ttatttatta agatgtttac agctgtaata agcaggaata ccgtttaaat 24660
aattaatatg tacttcacct tgaattaacg gatacaagta atcatataat tcttgggtaa 24720
tatcatttcc agcttcatta atccaggcag ttggaatttt ttgttctaag ttagctactt 24780
ttcttacatc agttgaaata taatcaattt cataaggggt atttgaaatt cgtttaaatc 24840
ccattacttg gccggatttt ccagttaacg cagtttctat tgctttttgt ccaactacaa 24900
atgactcatt taaatctgtt ttactcccaa tatgcatagc acatcgttgt aagacgttta 24960
attcaatact tctaacttta cattgaaatt ctttgaaaac taatgattct agcatttttc 25020
cagttcctga atgaagtaca tgaccaaaag cgtctttttt agcatattta gaatcatcat 25080
cgaggaagtg accatcttta tctttgatac cttcgcttac agcaattaca acacagcgtt 25140
tacgtttaaa tacttctcga atatcttcta agaatttttc tttatcaaaa actacttcag 25200
gtagataaat taaatcaggg gcttcattat attcattacg agccagtgca gcagctgctg 25260
tgagccatcc ggcatttctt cccataattt caataattgt tactgattgc agctgataga 25320
ttaaactatc atgaactact tctaagattg aagaagctac atatttggca gctgaaccaa 25380
agcctggggt atgatcagta cccattaaat cattgtcaat tgttttagga ataccgataa 25440
attgaatttc actattgatt gattttgcgt aatcatctag tttcatgaca gtatccattg 25500
aatcattacc accaatataa taaaaatcag taatttctaa ttcagttaaa atttcaaata 25560
attttacata tgtttcttgg ttgtcaatat gtgttggtaa tttaaaacgg catgaaccaa 25620
gatacatagc tggtgtttgt tttaaagcat taattttttc acctgtatca aattcctcaa 25680
gcaggtccat ataacgacct tctaataaac ctttaatccc gttgatcatt ccataaacat 25740
tttcatattc ttcgctatgt ttagctttat gaatgattcc agcaagactt gcattaattg 25800
cgattgtggg tcctccagat tgtccaataa tacaatttct ttttttcatc ttattctcct 25860
ttttcctgcc taattctatc atttttagac agtaaaaaaa agacatatta agtgattaac 25920
gtctttttct taaaataatg taaagaatta taattagtgc aacaaagata aaaatatttg 25980
caggctgagt cgtttgatgc cgattactag aaatgattga aattgacttc gtttcatcct 26040
gagttaaaaa atctaataga ttaatcttga cttgattatc ctggatcttt ccataactag 26100
tttcgctaat atttcccggc attttaatat ttaaatttag ctcgagtccc atagtcttca 26160
aatttgttag agaataatta ttaatatctt caatttcact tgtattaaaa atattgttaa 26220
tagtactgtg atcaatcgta acttgataag ttccttcttt tttatttgta gtgaagaaac 26280
tcaataagct tttattaata tcttttggtg caataagctg aaatcctata tattgggtac 26340
cattaatatc tttttttagt tctttatttt cccacgtact caactcacta ttagttaatt 26400
tatgttttaa atcagtaagt gaggtaccat aagaatctaa taaatcttct tgaatgagta 26460
cttcaattgt taaagatgca ttactttcat caataaattc gatgtcaaca tttcctttta 26520
cgcagcctgt taatgataac aacatgatac ctaccaaaaa taattttttt accatcatct 26580
acctcctaat gttagtgtgc cacaatcttc attttctaaa attaaaaagt ggatttaaaa 26640
ttgttaaatg atataattta atcatggtta acatatagtt cacaaaaaca ctttaaaata 26700
tagaaggtga tataaatgag agtagaaatt ctatatacaa gtaaatcaaa acacatcaag 26760
cctgttgctg aagctatggc aagatgggtt aaaacatatg caaagacgat tgatcaattt 26820
gatgctcttg ctccagtcga tttattagtt attggctttg atgattcggc ttggaaagat 26880
ccgcagttag agacatttat taaaagttta aatagacaaa aagtacataa tattgctttg 26940
tttaatgctt tctacattaa tgatcataaa atgaaaaata tgattaaatt atgtcaagaa 27000
acagatttac cacttatgcg tgagcaatat tcatttaagc ttacatttag gcagttaaag 27060
gaaattgatc aatgtgtaat agatgctgct cgtttatatg tagaagatat ggtgaacttg 27120
gtaagggatt attattaaat tagtaaattt atactaataa caaattatta aaagctatct 27180
taggatagct ttttcttttt attataaaga atttaaggaa atttattaat attttaatta 27240
aattataatt tgttaaaatc ctaaatttaa taaaaatata tatttataaa aatattaatt 27300
gacaataatt tattattctg atagtatttt tttaagattt aaaggcgata aactttaaat 27360
caaaaaataa agggggaatt ttaagtatga aaaaactaga aatcattatc agacctgaga 27420
agctagaaat tttaaaagat attctaactg attgtgggat taccggaatg atggtttcaa 27480
atattatggg ttttggtaat caaatgggct atactcaaca atatcgggga actaaatatt 27540
cggtaaactt agtttctaag ttacggattg aaacagttgt taaagatgaa gtagttgatc 27600
aaatgattaa agaaattaca accaaacttt catctggtaa tgtgggtgat ggtaaagtat 27660
ttgtttatcc agtagaacag gcagtacgaa ttcgaactgg tgaaacagga gaaaatgctc 27720
tgtaacagat ttataaaaat taaaaggggg atcaaatatg gaacaattaa ttaatattgt 27780
ttgggtgttt cttggtgcgg taatggttat gctgatgcaa gctggttttg ctattttgga 27840
agctggctta actcggcaaa aaaactgcaa caatgtttta atgaaaaata ttatggattt 27900
tgcaattgga tcaattatat ttttagtagt aggttttggt ttgatgttcg gcgaatcatt 27960
agggggaatt gtaggtataa caggattcat tgatccgacg acattaaatt tatcacagtt 28020
tgaggcactt tcaccaacag tatttatctt ttttcaaaca gtcttttgtg ctacggcagc 28080
aacaattgtt tctggtgcga tggcagaaag aactaaattt tcatcatatt taatttatac 28140
gttagtaatt agtttagtaa tttacccaat ctctggtcat tggatctggg gtggaggttt 28200
tttatcaaaa ataggattta ttgattatgc tggttctact gctgttcact cagttggtgg 28260
ttgggccgca ttaatggggg cagttgtttt aggtccacga atgggaaaat ataataggga 28320
tggcagtact aatgcaattc ctggtcataa tatcatgatg gccactttag gcgtatttat 28380
tttatggttt tgctggtttg gatttaatcc aggttcttct ttagaagcag caggttatat 28440
aggtcatatt gcgatgacaa caaacttatc agcatgtgct ggtgcattag tagcaatgtt 28500
tcttacttgg aaaaaatatg gaaaaccaga tgtttcaatg actttaaatg gtattttagc 28560
tggtttagta gcgattacgg ctggttgtca tattgtttca ttatatggtg caattgcaat 28620
tggagctgtt ggcgggattt tagtagttta tggctgtgaa atcttagatc aaaaattaca 28680
tgttgatgat cctgttgggg cagttggggt acattgttta aatggtgtct ggggaacact 28740
tgcagttgga ttatttgcat gcaatacccc agcaagtgaa ggaactttag gcttattctt 28800
tgggggtgga actgctttac tgattacgca attgattggt gtaattattg tagcagtttg 28860
ggtatgttca atgtccttca tcatgtttac tttaattaag aaaacggtta gggttgcgag 28920
taacacctca ggaagaactt gctggtcttg atttaggaga acatggttct gaggcatatc 28980
ctgattttct taaaaaataa tttatcgtaa ggttgggaga ccaacctttt tatatggaaa 29040
aaaagctcaa ggtgtgatac aattttatca attttaggag gagatactat ggataataaa 29100
aactatggtt ttgaaacatt acaaatccat gctggtcaaa agccagatgt gacaactaag 29160
gctacgggga tgcctttata tttatcaaat gcttttacat ttgaagatgc tgatcaagcg 29220
gcgcgaattt ttgcgttaga ggaaggagga tacttctatt ctcgattatc taatccaaca 29280
gttgatgctc tacaacaaag aatggcggct ttagatggcg gattcggggc tgtagcattt 29340
gcttctggaa ctgcagcaat tatgggattg attatgactg tgtgtgaaac tggagatgaa 29400
attgttgctg caaataattt gtatggtggt acgattggtt ctttatcagg aacgatggca 29460
ggaatgggat ttaagacaca ctttattaat ccaactgatt tagaggcttt aaaagcggca 29520
atcaacgata aaacaaaaat tatttttgtt gaatcggtag gaaatcctaa tggagatatg 29580
ttagactttg aagcaattag tgctattgct aaagaatatc aaattttatt tgttgttgat 29640
aacacaacac caacccctta tttatttaaa ccaattgaat atggagctga cttagtagtc 29700
tattcaacta ctaaatatct agctggtcat ggtaatgtta tgggtggtgt gatcgttgat 29760
agtgggaact ttaaatggaa agataatcct cgctatccat tatttaacat gcctgacaaa 29820
gcttatcatg atatagttta tgctgattta ggagcgggtg ctttttgtac taaagcagta 29880
gcaaagacat tacgtgattt aggagggtgt atgtcaccgt ttaatgcgta tatgacttta 29940
ttaggattag aaacattatc attaagaatg aaaaaacacg ttgaaaatgc ccgattatta 30000
gcaaaatttt taaatgagtg tgatgatgtt gaatgggtta gttacgcgga attaccagat 30060
agtcctaact atgaactagc taaaaaatat ttccccaatg gttttggtgg attatatact 30120
tttggagtca aaggtggtgt tgctggtggt aaaacagtaa ttaataatat taaattattt 30180
attcatgtta ctaattttgc tgattcacgt tcattgctga ctcatcctgc aagtacgaca 30240
catgctcaaa tgtcagagga agagagaata gcaggtgggg taaaacaaga aacaattaga 30300
atgtctgttg gtcttgaaga tgttgaagat ttaattgcgg atttaaaaca agcatttgct 30360
aaaatataaa ataattagga ctattgttta ttgttcaaaa caatagcctt ttttctagtt 30420
tttttattag tcctcatgta taattttaat gaggtgatta aatgcagagt tttttagcca 30480
tgcatattaa taatatagtt atgatcctgc tgctttttat ctatgtagtc tgtttaaatg 30540
gactattttc aatgcgacgt cgtcttataa aatggcgccg tttctttgcg ttcttattta 30600
ttattagtac cgcgggttta atgttaggaa ccattcgtaa tgagctgatg gtttattggt 30660
ttaataatgc tagttttaat attgagagca attttgaatg gatgattaag ataggttatg 30720
atctgattag tttaattatt atgattttaa tgattttttt ggtgaaaaat attttagatt 30780
ttattaaaaa tagtagtcgt gatgcaattc gtaaattagc tattaatgcc gatattatag 30840
ctatcttaat tattattaga actgtaatcg ttccgctgat tgttaaacta gctagagtat 30900
tggaattatt tggattaaat aatcaaacta gcagctctaa tgatatattt ctttatgctt 30960
tgccatactt gggattaccg gaggttgcaa ttattgttgt tacaatcttt atcaatatac 31020
taggaataag ttattggaat cgagatgctg aagatgttat ggcaaaataa aagttatgat 31080
ctagttagtt atctcgaaat aataataggt attattgcct tgatttgttt gctatcatta 31140
ctttatttgt ggtaccaacc caaatgtcaa aacaagttta ataatattgt ttttttagga 31200
cacttgataa tttgttttga tctttattta ttagtagata aagttgccca tttattaatg 31260
agcttttatc aggcttatct gcatcatcta aaatacaata tttacgatta tgcattatta 31320
agcagtgata ttttattaac agtggtttta atttttagta cttttttgtt tatcaataat 31380
ctagaacatt tattaataaa gaaagatagt aaagaagagt ataatttaat tttaaatcga 31440
gtttttaagg cctataattg tttgatggta gtatttattt ttaaagatgt tgtattaaaa 31500
attgtatatg atttcttggt agatgttaga ggaattaggt tacattatca cccttatacg 31560
attaataatt taatggttac aatcgtatta atgttgttat taggcttggt aataaatttt 31620
tataagaaaa aaacgacttg atctgcagca cttcttaaag ttagagtaac tttttgaaga 31680
cactacaaat agtcgttttt ttaatcaata accatagcat taggaatagg tgctaaagga 31740
ttttctttgt tgatacggtc atagaacaaa gttccctcga agtgatctag ttcatgttgt 31800
aaacaaattg ataagaatcc tcgagcaaca attttcactt cttgatcagt caaaacatca 31860
tatcctttaa cggtcacctt agcgtagcgt ggtacatatc cttgaacttc atcattaaca 31920
gataaacatc cttcaccatc ttttaaataa gattgttttt cggtatgtga aatgattttt 31980
gggttaacta aagcatagtc atcagcccca ataacatttc catcttcatc aaaatctaaa 32040
acatgaatag cagtcattcg tttaggaatt cctaattgaa tagccgcaat tcctacagct 32100
gggcgtaaat catatttttc agaagtttca gggtcttgag agttaacaag aaactcatgc 32160
atttgtaata aaagttcgcg ttcttcattt gtgattggta atgctacttc ttttgagacc 32220
tcacgaatct tttcattatg gtcatcaatt atatctttca ttgttatcat aggttcacct 32280
cattttaatt ctgatagtat tatatcataa aatgaggtga aataaagact ttatccgact 32340
ctaattcttg aatttccaca aatgattaat aataagaata caactaagac aatggcaaac 32400
cagtttgaag aaccgaaacc accgcaacca caaccgcatc cattgcttga aatgttacag 32460
ctgttgcatc caccacatcc aaatggatta gtgataaaag gattgtatga attacatcca 32520
catccagaat agttaaatcc gcagttcata ttatcgcctc ctttagtata tcctattcta 32580
atatttatct tttgtttggg ttattgtaga taatcgataa attttaagtt ataatataaa 32640
gcaattaagg agtgtgttag tatggattac aattatccgt tagactatag atggtcaaca 32700
gaagaaataa ttgatgtaat ggcattatat aatgctgttg aaaaagctta tgaagaaggt 32760
attagcaaag aagaatttat gcaggcatat cgtaagttta aagcaattgt tgatagtaaa 32820
agtgaagaaa agcaattgga caaacaattt tacgaaattt ctcattattc tatatatcaa 32880
gttgttaaag cagccaaaaa taatgatttt attcgagtag gtgaataaat tggcaggaat 32940
agaaaagatt aagcgattat ttaaaagtcg tggggtcgat aaaggtattt atgctagtgt 33000
ttttgttttg gcaatttttg gaataattat gattggttca gcatcagttg gaagtgtgac 33060
ttctcatggg gttacttatg ctttaaaaaa tatgattact caaagtgttt atgtaattgc 33120
tggggctggg gtaatgattt ttattgccag agtatttaaa actcggtata ttacttatag 33180
tgcatcgatg aaattatact tattaggaat ctttttaatg ataatctgta tattttttgg 33240
tagtactaaa ggctctcatg catggattaa atttggttct ttatttagta ttcagccagc 33300
tgagttcatg aaagttgcaa tgatactgat aatgagttat tttttaactg aaagtgataa 33360
agcctttgta gtaaaaggta gatttaaaac acaacagctg aaatctgctt tttataaaga 33420
aaagttttta aaatgtgttt tcctgccaat gatgttagta gcaattgctg ctggagttgg 33480
gatctttgtg caaaaagatt ttggaacaac tgttatttta gtaactattt gttttgtttg 33540
ttttattggg acaccgcgtc aatactttaa gaaatacaag cgaatcgtat gggtgttcat 33600
tggggtttgt ggagtattgt ttttaattat tgggacttca gtattaaaag gttaccaatt 33660
agggagaatt tctacatggt tagcaccatt aagtgatcct tatgatacaa gtatgcaatt 33720
atcaaatgct ttaattgctt ttaataatgg tggtcttttt ggtgttggtt taggaaattc 33780
aacccaaaaa tttggatata ttccagagtc acaaaacgat tttattggtg ctattatata 33840
tgaagaatta ggtatcattg gtttaggctt aataattatt ccaacatgta tcattatttt 33900
taagttatta aaatattcac aagaaattaa agaaaataaa tcacggatta ttttgttggg 33960
aattgcttca tatttctttt tacatttatt gattaacctt ggtggaatat ctggattaat 34020
tcctatgacc ggagtaccat tactgttaat ttctgctggt ggatcttcat cagttactgc 34080
atttgtagca gttggtgtcg cacaagcaat aattgcaaaa cataatcgtc aaaaatttga 34140
caccgattag gctaatatac atataatata ttaggtgatc ttatggatga atttaaagag 34200
ttcttaaaaa caatccctag tataaaacaa gatgttctta atggacgtta tacttggcaa 34260
cagttatatg aaatttttgt tatgtatggt aaagatgata aattttggtt accatataaa 34320
acaggtaata gtggttttga tttaaatatg ttactagaag taattaagaa tattgattta 34380
aatgctttat cgagtagttt aggttcaatt gaaaaagttt taaatgttgc tagtactttt 34440
ttagataaaa aagagcctgc taaggaaaga aaatggtatg atgaatgaag aaattagata 34500
ttatcttcgt tatcatccta attggtatat agttttatct cggtatcctc aagaatacga 34560
gcatttaatt caagaatata aagatggtaa aaatcaacaa tttattgaca agattgatca 34620
agtatccatg ttaattaata tggtagaaat gatgatgtag gtaagatgga agagatatta 34680
gataaattaa ttacagaaat aaaactggat cagcgatata ttgattatgt tgaagctgaa 34740
aagaaacttc ataatcagga gattgattca ttattgcatg aatatcaaaa taaactgaat 34800
caatatgatg aattaaagaa atataatcaa tatattgata atcaggagat taaagatgaa 34860
attcgtgatt taaagaagaa aattgcaagt aatgaagata ttttagatta ttattgtaag 34920
tatcatcgtt taaatgattt tttagatgaa ataactaaag tagtatttgg gggtatttct 34980
aatgagttag atttatcacc atatcaatta taagagggct tatgagagta attgcaggta 35040
agtataaaag tagacagtta aaaagtgtta aatcaaattt gacaagaccg acaacagatc 35100
gtaataaaga aaatctgttt aatatcattg gaccatactt tgatggtgga gcagtactgg 35160
atttatttgc tggtagtggt ggtctaggta ttgaagcatt atcaagaggg tatgaacatt 35220
tgtatagtgt tgataaccag tatgcagcat ttcaagtaat taaagaaaat tttacaatgt 35280
tgaaattagc taatgctcat gtatataaat tagattatcg taaagcatta aaacgatttg 35340
ctaatgaaaa acttaaattt gatttaattt tattagatcc tccttatgga aaaggattag 35400
tagatgatat attagaattt ctaattgtaa atgaaatgtt aaatgatgaa tgtatgatag 35460
tagtagaaga gttaaaggaa gtagaattta aaccatttaa agaattagat ttgatcaaaa 35520
aaaatgatta tggcattaca gctttaaatg tatttaaatt tatggcagga taggacgatg 35580
aagaaaaata ttgcggttta tgcaggaaca tttgatcctg taacaaatgg acatttagat 35640
attattgaac gagcaagcag aatgtttgat actttatatg taacgatttg tattaatcct 35700
aataaacaag gactcttttc aattgatgaa agaaaagaat tattaaaggc ggcatgtcaa 35760
cagtttgata atgtgatcat tgattcttct gataaattat cagttgaata tgctaaagat 35820
gttggttctc gaattattgt tcgaggaatt agagcaacta tggattttga atacgaatta 35880
caacttgctt tttctaatca atatttagat aaagaagtag atatggtctt tttaatgaca 35940
aaaccatcac attcatttat atcttcttcg gcagttaaag aaatggtgag ccataaccgc 36000
agtgttgcag ggctagtacc accatgtgtt gaatcagctt tacgaaagaa atatcaaggg 36060
gaataaatat ttcccttttt atatggtaaa ataattgtca aaataaccta tttttgttat 36120
gatgtaaaaa gaaaaaaaac tatgtcaact gggtataatt aatattattt cccaattata 36180
cctcgttaga ggtatttttt atggaggaag attatgaaca tatttacatt aaaagatttt 36240
tcaacagaag aaattaatca gattttggat gaagctgaag agtttaaaaa cggtaaaaaa 36300
gttgatttca aaggacaaaa agtagttgca aacttatttt ttgaaccatc aacaagaacg 36360
cattatagtt tcgataaagc tgcttataat ttaggttgtc gaactcaaaa ttttgaagca 36420
gcaaattcaa gcgttcaaaa aggagaaact ttatatgata cggttaagtt ttttgaatca 36480
attgggtgtg atgctgtcgt aattcgccat cccaaggaaa actattatga ggatttaatt 36540
gaaagaatta agattcctgt tgtcagtggt ggtgatggaa ctgggaatca tccaagtcaa 36600
tctcttttag atttaatgac aattcgtgaa gaattcggtc attttgaagg gttgaagatt 36660
gtaatcgttg gggatatcgt tcactctcga gtcgctcata gtaattatga gataatgcag 36720
cgtttaggaa tggaagtata tactagtgga ccacgtgaat ttgaagaagc tggatataac 36780
tatgttgatt ttgacaaaat tttaccagaa gttgacattg tgatgttatt acgagtacaa 36840
catgaacgtc atcatgattt gatgcgatta acgactgatg aatatcatca gatgtttggc 36900
ttgaatcaaa aacgtgttga taaaatgaaa gaaggggcga ttataatgca tccagcacca 36960
tttaaccgta atgttgaaat agctgatgaa attgttgaat gtgcacaaag ccgtattttt 37020
agacaaatgg aaaatggtgt atttgtaaga atggcattat taaatcgggt gttaacaaat 37080
gactaaaata ttattcaaaa atggtaatgt attttatcat aataaactcc aaaaattaga 37140
tgttttgatt gaaaatgatc gtattgcagc aatcgctcaa gaattaacgg atgctgatga 37200
gattattgat ttaaaaggta acttattaac acctggattt gttgatattc atgttcattt 37260
aagagagcct ggatttgaac acaaagaaac tattgcaacc gggactaatt ctgctaaata 37320
cggtggttat actcatctag ttgcaatggc taatacaatc ccatgtatgg atgatgtagc 37380
cacaattaaa gattttgctt tgcgggtagc aaaagatgcg aaggtacata cttatacata 37440
tagtgcaatt acgactgaat taagaggtca agaactagta gattttgatg ctaatagtaa 37500
agaagaaatt gtagttggtt tttcagatga tggtcgtgga gttcaatcat ctatgatgat 37560
ggaaacggca atgaaagctg caaaagcgaa taatagtatt attgtagctc attgtgaaga 37620
cgaagctgaa ttacagccag gtgcttgtat caacgatggt aattatgcaa aagaacataa 37680
tttagttgga ataaataatg catctgaatt taatcatgct gttcgtgatt taaagttggc 37740
aagtgaaatc ggaaatcgtt atcatatttg tcatatatca actaaagaaa cagtagcggc 37800
attaaccgaa gctcggaaaa caaatccatt agttagcggt gaagcatgtc cacaccattt 37860
aattttaact gatgataata ttaaggatat gaatcccaat tataaaatga atccaccgct 37920
tcgaagtaaa gaagatttag cggcattgat tcaaggaatc aataatgggg gtgtaactgt 37980
aatttctact gatcatgcac cacatgcgat tgaagaaaaa aataaaccaa tcgacaaagc 38040
tccatttgga attattggga atcaacatgc atttagctta atgtatacat atttagttaa 38100
aaaaggactt atttctttag aaaaagtttt gacatgtatg tctataaatc cagcaaaggt 38160
aattggaatc gagcatgatc tagaagttgg gttaaaggca aatcttgctg tttttgattt 38220
agaagaagaa tatgtaatta caaaagaaag tattaaatca aaatcaatta atacaccatt 38280
tcttgaaact aagtgttttg gagcattaaa gtatcatgtt ttagatggta aagttacaaa 38340
aatataggag gcattatggc aaacttacat gggatgatga agattacaag cattaaaaat 38400
attgcagatg atgtatatga aatgatttta gaaggtgaag gagctaaata tatcagtgct 38460
ccgggccaat ttatcaatat taaaatcaat gatagtttac aaccttattt aagaagaccg 38520
atgtcaatca gtgattatga tgatagtcat attgtgattg tttttaaagt agttggagaa 38580
ggaactaaaa tcttaaaaaa taaagaaatc ggcagctatt tagattgttt gattgggtta 38640
ggtaatggat ttaccattaa ggatggtaaa gctttattga ttggtggtgg attaggaaca 38700
ccacccctat ataatttagg taaaaagctt gcagccaaag gaatagagat aacgacagta 38760
ctaggttttg gcagtgcaaa agatgttttt tatcaagaaa aatttgctga attttctaat 38820
gtttttgtcg caacaatgga tggcagcacc ggaacaaaag gaacggttgt tgatgtaatt 38880
aaaaatgaag gtttgacttt tgataattat tatacttgtg gaccagaacc aatgctagat 38940
gctttagcac ttaattatcc agaaaatggg caattatcat ttgaagctcg gatgggatgt 39000
ggctttggtg cctgcatggg atgctcttgc aaagttaaaa ctagaccata taaaagaatc 39060
tgcgttgaag gaccaatctt agaaagtaac gaggtgattg taaatggcta atttaaaagt 39120
atctttacct ggtttagaaa tgaaaaatcc cattattcca gcgagtggaa catttgggtt 39180
tggatatgag ttcgcaaagt tttatgatat caatattctt ggttcaatga tgcttaaagg 39240
aactacgtta gaacctcgct atgggaaccc tctacctcga attgctgaag gaccaagtgg 39300
tttgttaaat gcaattggtt tgcaaaatcc tggtgttgat gctgttatgg ctgaggaatt 39360
agaaaaacta agaccgctat ataatgataa agtaattgct aatattggtg gtagtgcacc 39420
tgatgattat gtcgaaactg ctaaaaggat ttctactcat gacatggtag gagccttaga 39480
attgaatatt tcatgcccga atgtccatag tggtggaatt caatttggaa ctaatccaga 39540
aatggcagct gatttaacac gtcgagttaa ggaagtttct aaagttccag tttatgttaa 39600
attatcacca aatgttactg atattgtagc aatggctaaa gcagttgaag cggctggggc 39660
tgatggtata acgatgatta atactttagt agggatgcgc tttgatttta aaacaggaaa 39720
accaattatt gctaataaga cgggaggata ttcgggaccc gcaattttcc cggttgctct 39780
aagaatggtt tatcaagtaa gtcaagcagt aaagatacca gtaattggta tgggcgggat 39840
tcaaaatgcc cgtgatgtta tcgaaatgat gtcggctggt gcaagtgctg ttgcaattgg 39900
ttgtcagaat ttaattgatc catatgtatg tgaaaaaatt attaatgatt tagaaccatt 39960
attagaacaa attggtatta atgatataaa tgatttagtt ggacgttcac ataaatttta 40020
ataaaaatac tagagtttat tttaatacaa actctagtat ttttatttat tgtatcgttt 40080
ttctttttta tcgagtatta ctaaactaaa taaggcagtt tttagtaaat ttaaatataa 40140
taaattattg ctatctctaa ttttagcagt tatttattcc aaatcaaatg gttttatagt 40200
agaagtttca tttttagtat gaatatagtt attagggtca acgttttcat aattataaat 40260
caaatcatta agattattta aataatattt tctgattaat ataatggttt gtttatatat 40320
gcttgcactt aattaaattg tatagcctat tattgaggtt tacaagatga taaattatat 40380
tcaatatttg aaaaatgagc caagtattga acatagaaaa aacctcacta aacatagtga 40440
gattttttga gtgttttagt tatgtctttt cttttttaat actaatggta atactaacgc 40500
acccataata aataatgaag tgtatagagc gatatttgta ttatcactag ttttgacgtt 40560
accttgttta acatcgtctt ttttattagc atctggagtg ttaggtgtag ttggctctgc 40620
tggagtaact ttaactaaat tattgatggc attttgtaag ttgtcatatg cggtttcaat 40680
ttcggtaaca gtggcaactt cattggctgc aacagctttt acatcaataa gaatattagc 40740
taatgctgcc cagctttcac tagtgtattc tgcactattc aatgattcag ctttattaat 40800
taattcgtta agggcatctt tatttggttt tagtcttagc tgtaagaagg ctcttactaa 40860
tttatcgtgc gcttcttgaa cttctggttc taaagcattt tgattattaa caacaacttt 40920
agcttcatct aaaacaggta acattgcatt ccaagtgctt gttagataat cttcagcatt 40980
tagtttagca atttttttaa ttaaattttc taaattagtt ttatcacctt ttttgaaaga 41040
taatttttgc attacgtcac ttaaacggtc aaacgatgca tttacttctt cttgcgtagc 41100
taaagaagtt ccattgatct gttgagcttc tgctagagcg gctttaaatt ctgtaactac 41160
agcaggaaca atagtattta attctgcttc agtaacttta agtgcttcct caattgcaat 41220
atttaaaaga ttctttttaa ctactacgta ctcaacattt tcgtaattat aaatcaaatc 41280
attgataata tctgtgtaga aactatcttt ttgataatta gcagggtttg ctttaacatc 41340
actgatcata gcatttaaat tatcaatatt ttcttgaact gcagtatttg ttgtagtttt 41400
gtcagccaga gcggtttcga ttttatttat tactagatct agatcagtct tgttgtagtt 41460
gatttttgat tgtgtaaata aatcatcacg tggtgatcca agtgtataca tcagtctttc 41520
aaagctttcg taatccattt ccttttgata ttctgctccc catgttttta atgcaaatcc 41580
agcataacgt gggaatagtg tcctagtcaa aatatattct ggtacatacc cgtgggcatc 41640
atcccaaatt gggaatactt gtcctaatga cttgtcaaga ttttctgtta atacttcatc 41700
atttccataa tgatatgatg attttgaata atgatatctt gtaaattctt catatgtccg 41760
ttttggtaat ggacggtcta gtttgctctg tccttgttgt ggccataaat catgatagtt 41820
tgatgaagaa cttgacatga ttgtatatcc agcattagct gtagtactgg ctttgattga 41880
tccgtacatt cctccagccc agaaatcaac aattagacgg ctgtctaatg gtactattcc 41940
tcctaaatca aagatgttgt cattccatac tagtactttt aagttttgtt tgattagttc 42000
gtctcccgct tcattgaaga aaagtttgat agcatcatgg tctgtcgcag cttcatttcc 42060
tgtcacttga cgtgcccatt cctgtaaaac tgttttaccg gcagttgtat aaccactttg 42120
gaaatattca tcaccaccga tatgaatcgt tttagcatgg aagaaatctg ctgcttcttt 42180
ataaacagag atcatatatt cacgaacttc ctgtttagaa aagtctaatg ctttggttga 42240
accaggaatg caccatccgc tatggaaatt tgcttcttgt tcagcgtgac ctgggaagtc 42300
gatttcagga ataacttcga tattgaattt agctgcatag ctgactaatt catcaacttc 42360
ttcctgagtc caaaatccac ctttacggtc aacaaaatca gcagcaattt tcgaatcata 42420
acgaataccc tcgttgtctt taagtctcag ctgtaagata ttctgtttgt aatatgccat 42480
ttgttcaatc tgatctttta accattgaat tgaatagtat cttcttccag agtcgacctg 42540
aagcccacga acaacttgat cactgtaatc ttgaacagaa ccagcaggaa ggctttttct 42600
ttgagcgaag gcctgcaata tagtcattgc accattttga ataccttgaa tgtagtcaga 42660
atggatgaca gttttgtctt gatcgatatc gatttgatag gcatcgattt tgcttgctgt 42720
tacagctgca ggaagttcaa aagtgattgg ctgtttaact aaaacaatac cttcaccttg 42780
tgaggcatca gtaacagttt tgatcgtata gtctttgatc agcccttttt taaccatact 42840
gtcggctaga tattgggtct tagctttact gaattcatca gttgaaaaaa cttgcttagc 42900
tgtatttaat ttataaattt catttccatt tttttcaaaa ttctgaacag ctgggacagt 42960
ttctgggaat tcagagaagt ctgcatcata gttgatagaa gctttctctt caactgtttt 43020
gttttctact ttttcaattt tgaaatcatc gatatagaaa actccagaac ctaagtcatt 43080
accagtccat tccatatagg caaaaccgta aatttcatta gttctaggac cagtagtgat 43140
agtatgttca ttagtctgcc actcagtgct gaccttttgg ttagtttgga tattagaagc 43200
aagctgccaa ggagacgtag tatgcttacc ttcaatatca agaactccgg tagacatctt 43260
tactccggat tcattccagt aatgggtagt aatcttgtat gtagtgttag gctcaacgtt 43320
atggaaaata acattaacac tacctttacc ataattataa cgccagatag gaacttcaga 43380
aggattttca ggtttaggat tcccaacttt gatagagtat tttccgtcaa aagctttttc 43440
gtcagttctg acagctttgt agagttgaac ttcattttta tcaatttcgt gttcaaaaga 43500
cggattagta attagtggag catcggcagc tttaagtgga ccgacgttga tcgacatagc 43560
cataagtgag gccatgacaa tcggtaataa tctctttttc tttttcatat atctctttcc 43620
ctttcatgat atgataataa ataaaatata gcagttattt gcgataacac ctcctgatta 43680
atatgatgat ttgtctatac atttctgtat ctaactaaat tgtaaagggc atgaggaaat 43740
gttacaatat agaaaattgc aaatgatttt taatttttga atagattttc aaaaatagaa 43800
tatcttttca cttcttgaaa agtagtgtta taataatggc atgggttagt gctgttatag 43860
ttttatgaat aagaggggaa caataaaagc caaagaattt tgaagtagta cgggaaagga 43920
ggatatcgag gagattcctc gataacagac aatggctggt tttatttata aactgcaaaa 43980
tattgtaaac acatcaccag atagcgatga tacaaatata aatatcgcta gatgcatttt 44040
aaaaaatatt gataaaataa aaaaacggac ttcattgcaa gattttgctg atatttgtta 44100
tacatcacaa tcaagtatta gtcgtttttc gcagtattta ggttatgcaa attttaatga 44160
ttttaaagct gactgtattg ggattcaaga agaaacagat gaaatgatca tagatactcg 44220
agcgactaaa aaaattaatt gtgttgacta tgcccaagca atttctgaaa gtttagtaag 44280
aatgcaagaa acatcaattg atcaagaaat tgaacagttg tgtgagtata ttcataatgc 44340
taaaagaatt tttatttttg caactcatat tcctggcgat cttgcctgca ttatgcaacg 44400
tgcaatttta acaacgggta agtttattga attttatcct cgtaaagagc atcaaatgga 44460
ggttgctaag caaatccgtc gagatgatct ctgtattttt ttatcattag aagggacatt 44520
attaatggaa aaagcaatca ctattccagc aattatttca ttagctaaaa atgttctgat 44580
aactcaaaat gttcatatta aattttcaga acaatttaca caagtaattg gattaggtgg 44640
gcatgatagt gaaagtattg gaaaatataa gttattgttc tttattgatt gtttgttaaa 44700
tcgttattat cataagtaca tagtaaataa ttaaagtaga agtacagtta tttggacaaa 44760
taactgtact ttatttttaa aggatatttt taggtgttaa agaaaaaata tcttgagaga 44820
aataatattt tatatatctt ttatatttaa tatcatatat aatatatcgg tggtggtgat 44880
tagatggaat tagatgaatt attaaataaa aatcaaaaag aagcagcaac atatcttgat 44940
agtcatttga gaataattgc tggagcagga tctggaaaaa cacgggtggt aacgtatcga 45000
attgcttatt tgattgatga aatcggtgtt gacccgcgaa aaattctagc tattactttt 45060
actaataaag cggcaaacga gatgaaagaa cgaattacat cattattagg acctcatgca 45120
ttaggttcgt tagtttgcac aattcattca ttatgtgtcc gaatattaag acgacatatt 45180
aatgtgatta attatccaag taattttatg attatggatg aagaagatca aaaagcatta 45240
attaaaaaaa tttataataa tttagatatt gatgcaaaaa caatcagtat taaaagtatg 45300
attgcatcca tttcaaatta taaaatggct aatattgatc ctgaacgagc aatggaatta 45360
gcaggtcagt ttcaaggtga aataaagaaa gctaaagtat ataaagaata tcttgaatat 45420
caagaaaatc attttatgct tgattttgat gatcttttat taaaagcagt atatattttt 45480
gaaaattatc cagatgtatt agaaaaatgg cagcataaat ttcaatacat ccatgttgat 45540
gaatttcaag atgttggcaa tattgaatat cgtttagtta aattgatgtc acaagatgca 45600
attacttgtg ttgtaggcga tcctgatcaa accatctatt catttagagg ggctaatgtt 45660
aattatattc ttgattttga taaagatttc aaaccttgta aaacagtgat tttagaccaa 45720
aattatcgct ctacgggaaa cattttaaat atttccaata gcttaattcg taaaaatcga 45780
aatcgattag aaaaagacct ttatactgag gctactggtg gtagtgaagt tattcattat 45840
atgggaaaga gtgaacagga agaagcagat tatatttgta gccagattga aaaaataatt 45900
agtgaagttg acggagtcaa ttatcgcgat tttgcaattt tatatcgtgc taattattta 45960
tctcgaacaa ttgaacaaag tatgattagt catggaatag attaccggat ttttggtggt 46020
ttgaaattct ttagtcgaaa agaggttaaa gatgcattga gctatctgca gttagtatgt 46080
aatgatgaag atcttgcatt cgaacgaatt atcaatgttc ctgctcgggg aattggaaaa 46140
aaaacattag aaaatattca attagtagct ttgaataatc aggttagttt gtatgaggcg 46200
ttgacactat ttagtgatca aattaagctg tcatcaaaag ccaaaaaaga aataatcaca 46260
ttggttaaag ctgttgaaac agcaaaacag tcaagtctgc cgcttcatga aatgtttgaa 46320
aatttgatga acgatgttgg atatattgat atgttgaaaa aggatttaga agataatcga 46380
attgataata ttcatgagtt acaacggtca atttatgaat ttcaaaatca aaatcctgat 46440
attgcaacaa ttgaaaatta tttacaagaa atttcattat atacagataa tgataatttg 46500
gatgatggac aatatgtcag tctgatgtca attcatatgg ctaaaggtct agagtttgat 46560
tacgtttttg ttttaggttt atcggaaggg attttcccaa gtttcagagc attaagcgaa 46620
tcagatgaag gattagagga agagcggcgt ttggcttatg ttgcttttac tcgagcaaga 46680
aaacaattgt ttttgacaga tagtgaaggc tttagttttg taacagattc tcctaaaatt 46740
tcaagtcgct ttattgatga aatcgggagt gaggggatta agcatgtagg aacaaagcca 46800
cgatttaaaa cagcaaactt tattaataca gctccaacta aagaagaatt agtagggaat 46860
aatgaagtga ctgactggtc aaatggggac tttgttttac atgatacttt tggtaaaggt 46920
gttgttgtta aagtcaatgg taatacttta gatatagctt ttgaattgcc tgctggttta 46980
aagactttga tggcaaatca caaagcatta aagaaactaa caaattaatg tgctaaacgc 47040
acattttttg ttttatagtt atacgtattt tggtataata gttaagatta aattaggagt 47100
gagataatgg atgatttaag tagatataag gaactaaaag caacaatttt atatcataat 47160
gatcgttatt acaatcaaga taatccagag attactgatt atgaatacga tatgatgatg 47220
caggaattaa aaggattaga acaaaaacac cctgaatata ttactagtga ttcaccgact 47280
caaaaagtag gtggtagtgc aaagcgtgaa gctggtgtac tcgtacgtca taatgtgccg 47340
atgttatcat tgcaggatgt attttctaag gaagatgtag atgcatttgt tgcggatatg 47400
caagaacaac tggtagatcc gacttttgtg gttgaataca agattgatgg gttgtcaatg 47460
gcattgcgct atgtcaatgg taagcttgat gttgctgtta ctcgtggtga tggtgtctta 47520
caaggtgaag atgttactgt taatgctaaa gtaatcaagg atgtaaaaaa tactttaaaa 47580
gaaccgattg aatatcttga agtccgtggt gaagtctata tgaccaatga agcatttgat 47640
aaagttaatg aaattcagga aattaaaggg aagaaacttt ttgcgaatcc tcgcaactgc 47700
gctgctggaa cgttaagaca gcttgatagt tcaattacta aagagagaaa tttatcaatg 47760
tttgttttta atattcaaga tgctaaaggc agagaattta taagccacag tgaaggatat 47820
gaatatttaa aacggcaagg aattaaaatc attgaagatt ataaaatttg taaaacagct 47880
aaagaggttt gggaggcaat tgaggcgatt ggtgaaaatc gtgataaact tggatatgat 47940
attgatggtg ctgttgttaa aatcgatagt tttgctgatc gacaaaaact cggagcaaca 48000
gctaaagtac ctcgttgggc agtagcttat aaatatccgc ctgaagaaaa agaaacaaaa 48060
ttattagcaa tcgaattgtc agtaggtaga actggaagaa taactccaac agccattttt 48120
gaaccaattc gtttatgtgg aacgactgta tctcgagcaa ctttacataa tcaggatttt 48180
atcgatgatc tagatgtgcg gattggtgat acgatcgttg tttataaatc tggtgagata 48240
attcccaagg ttaaaggagt cgttaaagaa aaacgccccg ctgatagtgc tccatatgta 48300
attggcaata cttgtccagt ctgtggagct ccagctgtac gtgaaggtga taatgcggat 48360
ataaaatgca cgaatcatag ctgtccaagt aagttagtta gaaatattgt taactttgtt 48420
ggacgtgatg ctatggatat taaaggtttt ggctttgctt atgtagaaac attagtggat 48480
catggttatt taaaagattt aagtgatatt tatggtttaa ttgataaacg tcaggaatta 48540
cttgataaaa aaattattgg tttagttaaa agtacagata atttattaaa tgcaattgaa 48600
ggtagtaaaa ataatgatgc aattaaattg ctaacgagtt tggggattag taatgtggga 48660
aaatctgccg ctaaaagttt aatgaaaaaa tttaaaagta ttgataattt gatgaaagct 48720
agttatgctc agttgattga agtcaatgat attggtgata ttagtgctat ggcaattata 48780
aattacttta agaatcctga taatcaggca gttgttcaac gtttaaaaga gtatggagtt 48840
aatatgaata ttatcgaagc tcaagatggc gatgaacgtt ttgatggcaa aacatttgtc 48900
gtaacaggga cattaccaac tctttcaagg aaagccgcaa gtgaattgat tgagaagcat 48960
ggcggtaaag tctcaggttc ggtgtctaaa aaaacggatt acttattagc tggtgaaaat 49020
gcgggaagta aacttaccaa ggcccaaaat ttgggaatta atgtaattag tgaagaaact 49080
ttactagaga tggtgaagta gctaaaatag tgttataatg cactgtataa aggaggaaca 49140
ctagaatgaa aaaaatagtg gctttattag cgatagcatt ggtgctgagc ggttgtagtg 49200
atgctaaaga gaccgttgaa aatcaaacag caaatgatgt atccactacc gatagtttag 49260
atgattcatt ttatcgagta gttaatttta atacgaattt aagtcgagaa gattattata 49320
ctgcttttgg aaatactatg gattttcaaa caattggacg agaattacag attttatcta 49380
ctgatcattt ctcaactaat gattattata tgtctgaagg gcaatatctt aaaacggatg 49440
atatgaatca attattaaaa cgctctgagg atactagtaa atatccttat accttacaag 49500
cacagcgggg aactactatt ggcggagttg caaatccaat catggtaagt acagtgcatg 49560
aacaagatta ttatgaaaaa aacggatctg aatatgtctt aaagggtcta tcattagcaa 49620
tcgtactaga tcctcgtgat gaaaaaaatg aacgtttaga cacctcatta gatgaatcgt 49680
tagttgttga ttttgggcgt gaagcaatta gtaaattata caaatattta cagagtaaaa 49740
aagacttaaa agatattcct gctaatattt gtgtttatta tgcgactaat actaacgaaa 49800
gtgatattaa tggtcgttat attttaaaaa gttattgtga tggcagtgtg ggaaatattg 49860
aaacattaga ttacaaaaat tatatgttta caagtacaga agcaactgct gctgatgaag 49920
atacagcatc acaatttgaa atttttaaaa gtaatatgaa aaaagctgca actgaggcag 49980
ttggtgtaat tggctatggt cgttataaaa atggtcagat tcagtcaatg aaaataaatt 50040
taaaagtaaa tattaaaaca tatactgaat tgctttattt gatttctact gcagctgatg 50100
aattaaatac tcaatttagt ggttttgata ttaaagtatt agttagttca caagatcaac 50160
tagaggcatt gattgttaaa gataaaggtg aagatgcgaa gagtatcttg ttgtattagg 50220
aggtaattta tggaaaataa agaagaaatg ttaaaaaagc ttggattgaa aacaatgttt 50280
aatattactg atgcagaaat gccagagtta gtagaagaat atgagatttt tatgaatcac 50340
gttgccgtat tagagaaaat agacactgat ggtaaggcac cattagcata tccttatgaa 50400
attgagacat gctttttacg tgatgatgaa ccgattgatg taataagccg agaagatgtt 50460
ttaaaaaatg ctaagagtgt tcaagataat caaattaaag taccaaaggt ggtgggataa 50520
tgaaagttta ttcaattgaa gaattgcata atttaatcgt taatcaagaa atagatttaa 50580
atgaatatta ttatgattta tttaaagaag tggaatttca acaaaatcgc ttaaatgcat 50640
ttgttacaat cactaaaact caagcaatgg ataatattaa agaacttaaa atatctgatg 50700
aagaaatatt gaaagggatt cctggagtat ttaaagataa ttacaatact aaaggaatta 50760
aaacgacagc ttcaagtaaa atgctagagg attatgtacc agtttacgat gctgcggttg 50820
ttgaaaaatt atataatgaa ggtgttagtt taattggtaa atcaagtatg gatgagttag 50880
caatgggtgg tactaacaaa tccgctctaa ctgggcctgt atataatccg tgggattcat 50940
caaggatagc gggaggatca tcaggtggca gtgcagcact tgttggtagt ggggttgttc 51000
catttgcctt aggtagtgat accggagatt caattcgtaa accggctgga ttctgtggtg 51060
tagttggttt caagccaact tggggaagaa tttcaagatt tggtgttatt ccttatgctt 51120
caagtttaga tcacgtaggt gcttttactc gaaatgttcg tgatatggca attgtaactg 51180
aagcattagc tggtcgtgat gaaagagata tgacttcaag cacacggcca gtaccacatt 51240
atttaaaaga attgaatagt gatattagga atatgaaaat tgctgtttta aaaacagtta 51300
gtaatgaaat tagaaatgat gatattaaaa ataatttcaa ccatgtagtt gcaaccttaa 51360
aacaattagg ggcatgtgtc gaagaggtag aaattccagt tcatctagct aaagcaattt 51420
taccaactta cacgattatc gctaatagtg aagcaacaag taatcattcg tgcttagatg 51480
gaattaagta tggtgatcgg caacctggtt catcaactga cgaagtaatg attaattctc 51540
gaactgatgg atttggtgct catattaaac gtcgttttat tttaggaaat ttagccttag 51600
ctacagaaaa tcaggaacgg atgtttagaa aagctcaacg agtacgtcgt ttgattgtag 51660
aagaattaaa taaaatttat gataattatg atattatttt gactcctaat ggtggtagtg 51720
tagccccaaa acttgatgaa gcaaatgatg atcgcctatc agatgaatac ttgattttag 51780
aaaatcattt agctttagga aattttgctg ggacgccaag tatttcaatt ccgtctggtt 51840
ttagtgaagg aatgccgatt gctataaatc tgatgggacg tttatttgaa gaacaaacag 51900
tattaaatgt cgcttatgct ttagaacaag cattaggatt tgaaaatcaa tattcaagag 51960
aggggtagag agaatgaatt ttgaaactgt tattggatta gaagttcatt gtgaacttaa 52020
aacaaaatcg aaaatgtttt ctggggcccc agtaacattt ggtgaggcac caaatacaaa 52080
tgccaatatc gtcgatatgg ggatgacagg ggcaatgccg gtactaaata aatctggtgt 52140
tgaatttgcg atacgggtat gtaatgcttt aaatatggaa atagatgaac tggtacaatt 52200
tgatcgtaaa aattattact attcagattt accaaaagga ttccaaatta cgcaagatcg 52260
tttcccaatt gggcgaaatg gaacaatgaa gattgaggta aatggtcaaa cacaagtaat 52320
tgaaattgaa agattacata tggaagaaga tactgcaaaa caattacact ttgacgatta 52380
ttcattgatt gattataacc gagctggtat tccgttaatt gaaattgtta ctaaaccgac 52440
gatccgcagt ggtgcggcag cagctgccta tttagaaaga ttaagacaaa ttttcttatt 52500
tacagaagtt agtgatgcta aaatggaaga aggctcaatg agatgcgatg tcaatgtatc 52560
aattcgacca tatggtagtg aaaaatttgg tacaagaaca gaaattaaaa atttaaattc 52620
aatttcaaat gtacaaaaag caattgaatt tgaagttgct cgacaagaga aagtcttaat 52680
tagtggtggt gaggtactcc aagaaacacg ccgttatgat gaagatagta aagaaactgt 52740
agtaatgaga gctaaaggtg atgcagtaga ttacaaatat tacccagaac caaatatttt 52800
acctattcga ttgaatcatc aatgggttga aggaattatt gaaagaattc cagagatgcc 52860
agaatcacga gtagctcgat acataaatga atacaaaatt cctaaaactg atgcattgat 52920
acttgttcaa actaaagaag tttcggattt ctttgatgcg acagttgctt atactaagca 52980
ttataaaatt gcatctaact ggttattagg cgaggtacaa gcatatttaa ataaaaataa 53040
tttgattatt acagatacta atataactcc tgagtattta gcaaaaatga tcaattatat 53100
tcaagatgga acaatctcaa gtaaacaagg aaagaaagtg tttgaaatct tgatgaatga 53160
aggtaaagat ccagaaatta ttattgaaga aaataatatg aaacaaattt cttcaccgga 53220
agaattaact aaaattatta atgaagttct tgataataat cctcaatcaa ttgaagatta 53280
tagcaatggt aaagatcgag ctgtgggatt cttagttgga caaattatga aaaaaaccgg 53340
tggtcaagct aatcctggtc ttacaagtaa attactaatt gaactattga aacaaagaat 53400
ttcataatgt acaaataatt ctatatttgg tacaatggtt gaaggaggat ataaatatgt 53460
ctcaaagaaa aagatttagt tttgatgatg aagtagatga tacaattgat ctatcaaaag 53520
atgatcttaa aaattcatca ataactaata atgataaacc ttcaaacgac aatgtctttg 53580
ctgatgaaga tggtttagat gccaaagctt atcctactga taacggggga gataaatcaa 53640
tgaaaaacaa gaagaaacgc aagtttaaaa ttaagaaatg gcaaattgca ttaattgctt 53700
ttctatcaat aattattgtg ttcgtcatct atgtatttgt tgctggagga aatgatggac 53760
cagtttatgg tgatcgttgt gcttctttaa ttgcaattga caaaagtaaa tttacaggag 53820
ttgaagatgc aatcaaagca gacccaagcg ttaatagtat caatattgaa gtagattgtc 53880
gaattgttaa aattagtatg aattttgttg ataatacttc ttcagatact gctaaacaac 53940
tggcaacaaa cgccttacac acattagatg atactttagg tgaaaataag gaagaaggta 54000
gagcatatag taatttattt actactgcta atggccgtgg acaatacaac gtagagtttg 54060
ttctaacgag caatggtgat actaatttcc ctatatttgg tactaaacat ccaaatagtg 54120
atgatattac ttttactgga gctaatgtag ttgatcaagc tgcaactgat cgtgcggcta 54180
atacgaacgc taatcaatag acgagcatgg ctcgtcttta tttatgagga ggactaaatg 54240
aaaaaaaatg attattttta tggtgaatgc acagatttaa ctcacgatgg tcaaggagtt 54300
gttaagattg ataactttac atactttgta aaaggtatgc ttacgggtga aagaggacgg 54360
ctaaaagtaa taaaggtatt aaagaattac ggaattgcac gtttaattga attagaagtt 54420
acttcaaaat atcgtattga tcccaaatgc tctgtcttta gaccatgcgg aggctgtcag 54480
ttacaacatc ttaatcctca aggacagatg atttataaaa caaaacgggt caaagattgt 54540
ttagaaagaa tcgggaattg taaagtggcg gtaaatgatt gtattatgat ggaaaaaccg 54600
tggcattatc gcaataaagt tcaaatgcca gttggagtta aaggaaatca tttagtaact 54660
ggtttctata aacaaaagtc taatgaaatc atcccatgtg aaaactgtta tattcaaaat 54720
gaattatcaa atcagataac taatcgagtt aaagaattaa tggaagagtt taaaatttac 54780
ccatatgata agttagctca tcaaggtaat attaagcata ttttgactaa acacggttat 54840
catacagacg aagtaatgtt agtactaatt agttatcgta ataaaattaa agatatagat 54900
aaattagtgg aaataattac aaaagaattt ccaatgatta aaacagttat tcaaaatatt 54960
aatcatcgca ctgataatgt aattttaggt gaacaagaag tcattttgtt tggtaatgga 55020
tatatttatg atactttatt aggtaataaa tataaaattt ctttaaaatc tttttatcaa 55080
gttaatccaa tccaagtaga gaaattgtat tcaaaagcaa ttgaatttgc tggtttatct 55140
aaagaagaca tagttttaga cgcatattgt ggaattggaa caattacatt atcagtagcc 55200
aaatacgtaa aaaaagtgta tggtgttgaa atcgttgaaa cggcaattga tgatgcaaaa 55260
aataatgcag ttttaaataa tattagtaat gctgaattta aatgtagtga tgctggtaaa 55320
tatatgctag aactagttaa tcaagatcag catttagatg ttgtctttgt tgatccacca 55380
cgtaaggggt gttcaacaga atttttggat aatttgattc aagcagaacc caagaaaata 55440
atttatattt cttgtgatgt agctactcaa gcacgtgata tcaagtatct tcaagaattt 55500
gggtatcatg ctgatgtctg tcagcctgtt gatatgtttc ctcacacaac acatatagaa 55560
aatatagttc gtttgtcaaa atagccatga taaaaataat tactaaacag atttcctaaa 55620
agaagtctgt ttttttataa tttatgacga gtaaattgat ttcaattgtt ctaaatctat 55680
aattatagta aaattagata acctaataaa agcgggcgac tgattgtgaa aaaatggtat 55740
aatgaagaat atgaatttac aattgaagta acagttttta cgtgggaata aagcagaaca 55800
ttattgctgt aatggtgaag aaattggtga taaatacact tgtacatatg gttgctctaa 55860
gaggtaatga tgatcatgtt tccaattata ggggtagtta gattagaaat aggggaaaca 55920
aaatgaatgc atttatttta cttattcctt ttttattaat agcatttatt aacgaaggtg 55980
caatcaaacg ggctggatat tttgctccac tgcaaggcaa tgagaaaata gcttatgtaa 56040
tttatcagat ggccaatatc ggaatcttta tatatttttt cttatcagta ataattgatt 56100
tatcttggca gttttgttta ggtctactgg tttatttgtt aggattggga atgtgcattg 56160
ttttggttaa agattttttc tccaagaaat gatggcttaa atactaacga gatttaccgt 56220
ttctctcgaa atccaatgta tatgtcatat tttattttct ttttaagaac cgtattatta 56280
acacaatcaa taatcttatt tataatttta ttactatttc aaatctctat acattgggtt 56340
attctttcag aggagcaatg gtgtatcagc aagtttggaa ttgcttatga acaatatatg 56400
aatcaagtaa gaagatatat atagttaaat aaagaattat aaaaagaaca ataataaata 56460
ttagtagcat acttatgatg tcttattgtt gttttgaagt aatattaatg gtatactgag 56520
ttccagtata gaggtgcgaa aatgaaaata gagtttaaaa tgtcttataa attaggatta 56580
ttagaattta aagttggcga tcaactagaa attagtaaga acactatatt tgaaagtata 56640
aatgataagt attatatgtt aattttaaaa ggattgcgtt atgatcttct taaagaagat 56700
attaaaatta ttcaataaaa tatttaattt ggctatatct tagtgattag ccattttttg 56760
ttatggaaaa taaacttaaa ataattttat tatctgtgct ataataaata ttactaataa 56820
acatttaata tttaacaatt attatttata aggaggaaat atgcaataca tatctaaata 56880
tacttcaccg ttaggagcaa taacattagc tagtaatggt gaagcattaa caggtctatg 56940
gtttgatggt caaaaatatt ttggcgctaa tttatcaaaa gaatataaga acgtagagtt 57000
accagtattt aaacaaacaa aggaatggct taacttatat tttaatggtc aaaagccaga 57060
ttttattcct cttttggctc ttcaagcaag tgaatttcgt cttgctgtat ggcaaatatt 57120
gctagaaata ccatatggac aaaccctcag ctatggcgac atttcagccg ttttagcaaa 57180
gcaaaaaggt ttaaaaacaa tgtcagcaca ggctgttggc ggtgcagttg gacacaatcc 57240
gatctcaatc attattcctt gtcatcgagt cgttggaagt aacggaaact taactggtta 57300
tgctggtggt cttgaaaaaa agattgcact gcttcaatta gaaggagcgg atatgggagc 57360
gctgtttact cctaaaaaag ggacagcatt ataagttaat taaacttaaa aatggaggca 57420
tttattatga atgattttgt gaatcttatt aaagatgaag ttataaaatc tccattttat 57480
tatagtcaag ggtaccaata tagggattgg agattactgt tttattaatt ttgattgtat 57540
tttttagatt tgaatataat aaccttgagt taccatgtaa gaaatatata atttatgcaa 57600
taaattgtaa caaataaatg aatatagtat aatatattta aatattatag gaaagaagga 57660
atgtagttta tgaacaaaga agtattaaat tatattgctg aaaagacacg tgaattgatt 57720
gttgctccaa cttgcagtaa tgaaacaaag gaagctgccc aagcatggtt aaatgcgatt 57780
ggaacagaaa gcgaaatggc tgagactaag aaatatatcg ctgaattaga agaagatatt 57840
atgccaattg ataatttaat taggtttgct ggttctgaca atggtaaagc ttattttggt 57900
gaagaaaatg ctaaaaatat tgaaagccat gctaaagaaa ttaaagctaa cggggctaaa 57960
tattgcgatt gtccggcttg tttagttgtt gctcaaattc ttgaaaagaa gtctgaatta 58020
tttaatgaaa aataataggt ttatgaaaat attgttcctt taggaacaat atttttattt 58080
aaaatgtaaa tcctttttac aaaaatattc ttttttaagg attgatttgt aaaacctctt 58140
ctaaatagac tttaatgtat ttaagtaaat aaaatatgat gttaaattaa atgcaagaaa 58200
atattagagg aggagtttaa atgagagcag taacaacaat atttcctgtt atatttatga 58260
ttggaatagg aactttttca agaataagag gttttattac accaagtcaa aaagatggag 58320
caaataaaat agtatttaat attttatttc caataatgat ttttaatatc ctttttactt 58380
ctaagctaga gacttcagct atttttattg ttttatatgt gtttattgca tattgtgtta 58440
ttttgtttat tggaagattt ataataaatt ttactgggga aaaatttgct catatttcac 58500
cttacttgtt aacgacatgt gaaggtggta atgtagcttt gcccttgtat ctatcaattg 58560
taggggcttc aagtaatact gtaatatttg atttagcagg tgtttttatg gcttttgtaa 58620
ttattccaat tatggttgca agagcgggtg ctggtgaaac aaggattagg gaacttatta 58680
aaacaattct aactaattca tttgtaattg cagttatttt ggggttagga cttaatttat 58740
taggtacata taatttttta tcaaacagtt catatttagg aatatacagt aatacaatca 58800
cccaagtaac agcaccgatt gtaggcgtaa ttttatttat cattgggtat gatttgaata 58860
tcaatatgga aatattggga gcagtgttaa aattgttagt tgctagaatt attttttata 58920
ttctagtgat tattggtttc tttatcttct ttccagggct tatgattgat aaggttttta 58980
tgattgcagt tttgatttat tttatgagtc ctactggttt tgctattcca atgcagattt 59040
cccctttata taaaagtaat gatgattgcg gttttgcttc ggcaatcatt tctttgaata 59100
tgataatcac tttagtagtt tatgctttga tcgttgtgtt tattgcttaa tgttagtatt 59160
gttaataaat ttttgatatg gcataatgaa aatatattat tattggagat agtttatggt 59220
tatttgattt taacatattt ttagtagccg taagagaaga aaatatgact aaagcgtcta 59280
aattatatat tcaatttagc tgatattgct atggtggttg atgcagttgg aagaagaatt 59340
aggtgtaaaa ctatttaaga gcaacaatca cagcatttat ttaacagatg aaagaaaatt 59400
gtctagtaac gggctcaaga aattgttaat ttaactaaaa aggtgcaaga agaacttatt 59460
aaagatgaca tggctttatc tggtgttatt acgagaggtt gtggtggaat gcaaagtatt 59520
gaagaagcaa caagattaat aactgataaa aaagacttat caacaaagga gtattaataa 59580
tatggatagt acaataaaat tcgatggcct agcaaatctt tatgaggatg gtagaccgga 59640
gtacccgact atattaatag aaaagttata tactgactat ggttttaaat caacatccat 59700
aatcgcagat ataggtgctg gaactggtaa attttcaaag ctgttattag gacaaggtag 59760
taaggttttt tgtgtcgaac ctaataaaga tatgagaaat gaattagtca ataaattaaa 59820
taaatataat aaattgcatg ctatcaatgg aactgctggt aatactacgt tagatactag 59880
ttctgttgat tttattacat ctgctcaggc atttcattgg ttcaatgttc atgagtttaa 59940
aagagaatgt aagagaatct taaaattaga agggcgggta gcattggttt ggaatgtacg 60000
agaaatggag tcaccattga atcaagagtg ctttcaaatt tataaacagt attgccaaaa 60060
ctttgttggg tttaatggtg ggattaaacg cgatgatgaa agaataaagg aattttttga 60120
tatgcactat aagcgtatgg agtttccaaa tcctttattt tttgaccaga agggttttat 60180
taagcgctgt atctcaggtt catattcttt aaaaaaaact gatcagaatt attttgaata 60240
cattgctgcc ttagaaaatg tatttgataa atatagcaat aacggacagt tagtaatgga 60300
gaataagacg gttgtttata taggaagatt aaaataaatg tagttcaatg tcaatgagaa 60360
atacttttat agctttacca ttagttaaag gggcatatat gattatatag tcataaaagc 60420
gctttcttaa tttaggcggt aataggaagg aagagatggc catgtaccat agattcccaa 60480
ctaaatatct tgaattagaa ttgactgaaa caatggtctt tgcctaacta gaagttttta 60540
gtaaaattat tgagaaaatt cattaggctg gattcaacta ctctatggat gattttggaa 60600
gtggctattc ttttttagga atataaaaag attcagatat cgttaagctt gatggtacat 60660
tcttttcttc tgaaacgatg aataagggga aagaaaatat tattgataag aaatagtgat 60720
taaatcactg aacaaattat ttatagttaa cattttgata gcattatcaa acattagata 60780
ctattacatt gattaaagct atattataat ataattggat ttaaaatttg agatataaat 60840
gtaagggagt taaaccatgg gctttaatga tgaaagaaaa cgaatgaatg agggtgaact 60900
ttatcgttca aatgatgcgg aaattctaaa agaacaacta cagtgtgtag aaaaattata 60960
tgattataat gtaacaaggc cttcagaaaa acaaaaacgt aagggattgc taaaagaaat 61020
gtttgcagtg attggtgatg gatgtcatat tgaaccacca tttcatgcta attggggtgg 61080
gaagtatgta cattttggta aaggagtata tgccaatttc aatctaactt tagtagatga 61140
tgttgagatt tatgttggtg attatactat gatgggtcca aatgttacaa ttattactgg 61200
aactcaccca attttaccgg aattaagaaa agaagcatat caattcaatc ttccagttta 61260
tattggtgaa aatgtatgga ttggtgctgg aacaattatt ttaccaggta ttacaattgg 61320
tgataatagt gttattggtg ctggaagtat tgtaacaaaa gatattccta aaaatgttgt 61380
tgcttatggg caaccatgca caattaaacg ggaaataaat gatcatgata aaatttatta 61440
ttataaggaa agaaaaatca aaagtgttta atatttttga tttttttatt tatggattaa 61500
atacgtatta ctaataatat tagtaatagc tttaggttta agctataata taaaagtata 61560
atgtaatatt attgtgatcc aatccaagaa gatagtaaga tgcttaaaga agcaaagaat 61620
gaggatttag aagcactacc agaactttat acacaatttg aaaacgtggt tactgcttaa 61680
gcattggaaa gttagccctt gttcaatgac tctaaatcaa tatgcctaat caaattaata 61740
ttaatgatag aacaaaagaa ttcaaaataa gaagatattt attttatttt tattgcaatt 61800
tttttattat cttatcattg ttaaaggtga aaatgcctag cactgagtct atctgtttat 61860
aaaggtttat ttaatagttg acagtaaaaa atagttagat aataattagt aaattaaaat 61920
tttgattgat aagggggagt atggtgatgg agaatatatt agtaattggt aacggctttg 61980
atattgcaca tggttttaat actcgttacg aagattttat aaatttttgt aagactattg 62040
caacggttta tcaaggattt aaggataatc aattcatata tcaaaatgaa tataatgata 62100
tattaaaaga aaaattagat aaggttttta aagaaaagtc ggtttctgcc aaagcaataa 62160
aatatttttc aaacttaact ccaacatctg aaacttctca atttatcaaa gcatgtaaag 62220
aaaattattg gcttacatat gtcttaaaaa ataaaagtat gattggggat aagtggtcag 62280
atcttgaata tgtcattgct aaacaaatag agatattatc atatatttca aataatctta 62340
actggcatac tcgagaagaa actatgctcg cttcacgata ttctagtaat ttaattgaat 62400
tatttaagat tgtaacagaa gaacgtggaa ataataccga ttttcagcat cagatagaac 62460
tcacaaagaa acatttatat cgagaattgg aagaattaac atggttatta gaaatatatt 62520
taacacgatt tttaaatact aaaaccaaga aaattgaatt atttaaatat ttaccagtaa 62580
ctaaactcat ttcttttaat tatactgata cgtacacaag aatgtataaa aaagaaacaa 62640
atacagttca ttatattcat ggatttgctg ctaaagatag gataaaagaa gaaaataata 62700
tggtttttgg aattggctca gaaattaaaa atgtcaccga taatgataag tatgattatc 62760
ttgaatttca aaagtattat caaaggattg ttaaaaaaac aggtaataac tacactaaat 62820
ggttaaatga caatgaacaa ttttatatct atttttttgg tcattcctta gatattgtag 62880
atggagatgt aattagaaaa ctgattcatt gtaaaaaagc aaaagtaatt atcttttatt 62940
ataatcaaaa agccttgaat gcattagttg ttaatttagc aaagatttta ggaaaagatg 63000
aacttattca attcactaat gaagaaaaaa tcacttttta taaatctgat gattttgaaa 63060
taattaaaaa acttaaaaat acaatgtatc aaactcgtca tgagaagctt aagagtacag 63120
ttagataaat ccaattagaa atgaggaaat aatatggaga aaatcattaa agtgggaata 63180
ggtgttttgt taatcaagaa taatcagatt cttttaggac atcggataaa agatggggtt 63240
gatactggtg gcatctatga accggacaca tggtgtctac caggtggaaa acaagagtat 63300
catgaaacta tttttgaagg agcaattaga gaagttaaag aagaaactaa tttaaatatc 63360
tcacagatag aagtttttaa tgtagtcgat gatattcaat taaataagca ctatgtaacg 63420
atacatatta ttgctaaaaa ttacgatgga gatttaaaag ctatggaacc agataaacaa 63480
gatgagtggt gctggtttga aatagaaaag ctgcctaata atatttattc cccttcaaaa 63540
aaatttattg aagcatattt agatagaagt atcacctaga taaatcttat tataagaacg 63600
atatttttga aatcattggc gttgaagaat agactaaata cattattaac aatgtggtta 63660
acacgtgttt atactattaa aggaaatatt atgaataaat atacaatgat aaaagaagtt 63720
atttgaaaaa caacaagata ttaaaaaagc agataaaacg tcaaaatata tgagagattt 63780
atttacattt tatggaattc cctcacccta gcgcaaagat aagacaaata caaacttgct 63840
ggagcaaaaa attgttaata gttttggaag tgatgagttt tttattaata aagcaattgg 63900
ctggagttta agaaattatt ctagaactaa tttggtatgg gtaataaact ttattattaa 63960
atatcgtact ctaatgaata agctaagtat taaagaagct agtaaatatt tataatttat 64020
agtgttgcat gtattttttt gatatttaag atggatataa ttgataatat acaaagttat 64080
tataagaata tattttatga aagagtattt cgcctgtagg tatgatttgt taatagactg 64140
tttattctga gagtctgaca aatcttaaag attgagacgc atatgagtct gttattttat 64200
atagaaaatt ttgtagttgt aggaaggaca tatcctttaa tatataccga ggaaaaggaa 64260
aaaggcaaga cattatttat tgaaatacta ttaattggag ttggactcgc aatggctaca 64320
ttgttgtatc aatttataaa gcttaaggaa taaaaaatag ctaattatgc tattggaaga 64380
attgatatta gaaatacagt tttaaaagaa tattacctcc attgattatt gggtagtgtt 64440
acttttttaa ctattattga tggaaaatga tttttgaata tttaggaatg cttgtatttt 64500
tatatataag ttaaaagagg ggaaacatga cagtctctct tcttttaacc cttcattcca 64560
atataaatac caattatata aggaatcaac catattgacc aaacgataat actaaattta 64620
tgaaaagttt ttttagcacg atcatttttt ttaattagta ttactgttgc ccaaactgca 64680
tgaaaagcca ttaaaagtaa agcaattgat ccagtaatga cgtggagatt aaaattaaaa 64740
ttgtgccctg atatttgtcc cataatattc gttcctgatg tatcacaaat aaagccaagc 64800
caaaatatca aagcatgcca ttttagtaaa ctgccactct tttttcagca aaaacaccga 64860
ttgtataaaa aaccagtgct agcgtcatga aaataattgc cataataagt aatattgaca 64920
tataaatgta tttctcctta atctgtaaat tcttttttta aagaaattaa taatattagt 64980
aatgcaatca tcatagtaat atgtgaaagt cctgcaaaac cagaaagcat cttatctatc 65040
aaactattta tagccgtatt agttatttgt agaatcccac gaattagcat agtgaggatc 65100
ataaaaggta aagaaaaatt ataaatgatt acaaattttt taaatagtcg attattttgt 65160
atatttgtca cttttgcaat tacagctagg atgataaaca gtaatgttcc taaaattaat 65220
aaatgaggat gaattacact taatacggta ggcattgaat aagcataaaa ttttgtaaat 65280
tcacgataaa aaacaccccc agccattgct aaaataaaat atataatagc aatatttatt 65340
aaagatttag gagaataatc taaagtctta tttaatgatt tatagtaatt taaaccaaag 65400
atgataccgg ccaaaaatag cgcagctcct aaaccagtat agaaaatagc gataaatcta 65460
tccggtaata aattaaatgt tcgaattgtt ataccaaaaa ttatcataaa tgccataata 65520
ataaatgatt taagatcaaa gaaatttaaa aagaattgtt tttctatttc atagctatga 65580
attctatggg tatgtttttt agttaatttg taaaatatag caaaccaaaa aataataaaa 65640
acaatgattg agagaaagaa atttaataac tttgtatatc caacatatgt ttcaattcca 65700
atttttaaaa tattgaaacc agcaataagc cacacgattg aagctattaa taataaatta 65760
tactttttta ctttcataat aaacctccat aattaatctg aacactgttc actttgaatt 65820
ataagtattc ccacttcgta ataagtgggc tagtataaat atcgttcaac taactcaata 65880
ataccttggt agttttgttg tggattaacg attgaaaaaa tgaaaagttc aaaaatatac 65940
tcaatgaata aagtttgatc taatttttga ttaaaagcat cttttcttat tttttgatct 66000
ttttttaata caattaataa attttgtttt aaatggaaaa aatatttttt catcattttt 66060
tgtccaacga ctttatcttc agcagctaaa gacattgcat gttttgaaag aaattcagga 66120
tattcttggc tgccttcttg aatactttca aataaccaag tcaaacattc aatgaaattc 66180
gtaaaactaa attgttcact agacatgtga aaaatatctt tccaaatact ttcgatagtc 66240
gaacataaga gttctgattt tgatggaaaa tagttatata ttgcgcctac tgaaacacta 66300
cattcaattg caacagaacg catattaatt gaagatagac ctttttcttt agctaaacgt 66360
tgacagatag aaattatttc ttcttttgat gttgatggta aattcaaaat atttcctcct 66420
tataatttta tatgaaccat gttcatgttg aataatacgc cttattttta taatagtcaa 66480
acataatgac tttgcttttt tatcaattat tttaaatgaa tctagagttt ggctgattac 66540
tattttatgt tagaatgata gtatcaaaat aaattatatt tgaggtgaaa aataatgttg 66600
attgttgatg gagaaaaata tcttgcggaa ataaaagaat tgatcattga gtatacaaat 66660
tcattgaatc gagatttctc ttttcaaaac atagatgctg aattagaaga tttaaaaaga 66720
agatatctat agtctcatgg gcgtatttta gcggttgtcg actgatggta aagctgttgg 66780
ctgtattgct tattgtcacc atcgtaatca atgctgtgaa atgaaacgtc tatatgtaaa 66840
accagatttt cgtaatcagt gacaaggtca aaaattaatt gaagcaatta ttgaaactgc 66900
tcaaggagat ggttttggat acaatcaaac cgttaaaaag ggcgatttcg ttatataaaa 66960
aatatgtttt taaaaaaatt gaaccacatt atgataatcc aacggatgac gtaatttata 67020
tgaaattagt attctaataa gcaaagaaag tgagataggt taatgggaat attattggtt 67080
aggcttattg atgtaataaa tgaatatagt gaagatagta ctttttatag tattgcttat 67140
acaatgcttt tgaattttga taatttgcaa aatcttagta ttaatgatgt tgcaaattta 67200
tgtcatgtat caaaatcaac tattagtaag tttgtacgat cattaaattt tgaagattat 67260
tccgatttta aggcagaagc atattttaag gaaaatcgtt ttaacagtga ttataattat 67320
gttgccaata tccaacaata tattgctaat caagacgcaa atacctatat tgacaaagtt 67380
attcaggata ttgaaataat caaaaatatt gatatgacag tgattagaaa aattgctcaa 67440
ataatttatc aatatccaaa agtcacggca tttggaacac ttttttcaca attgggagcg 67500
ttagatttgc agtataaact ggcctataat cataaattta ttatgagtta tgtaaatgat 67560
gttaaacaag acgaatactt aaaaaataat agtgaacaag gtgttgtgat catttattct 67620
aattctggta actatttaaa taagtatcag ttatcatcat ttgatgaaaa gaaaaaatac 67680
gactataaaa ataaaaaggt tattttaatt actgcaaacg aaatgatggt aaatcatccc 67740
gatgttgata tttgtcttgt ctatcagcat ttatctaaat tacaaacaca tagttatatc 67800
tatcctttga ttaatgactt gattgttgct gaatatagaa gtttccaaaa tgcgaacttt 67860
taagtttata taaaaaactc cgttataata gtagtatcaa aggaggaaca aagtatgagt 67920
agatttccag ataatttttt atggggtgga gctagtgctg attttcaata tgagggtgga 67980
tttggtgaag gtaatcgcgg cttgattaca gcagattttg taacagatgg taatgttgat 68040
acgttacgtc aggtaactta taagtgtaaa gatggaacgc ttggttcgtc accattaaag 68100
gctgaaattc ctgaaggagc aactggatat attgatcctg agcgttatta tccaagtcat 68160
gatggagttg atttttatca tcgttataaa gaagatatcg ctttaatggc agaaatggga 68220
tttaatgttt atcgttttag tatttgctgg acaagaattt ttccgacagg cgaagaggct 68280
gaaggaaatg agttaggttt gaagttttat gagaatgtta ttgatgaatt attaaagtat 68340
cacatagagc ctttaattac aatttgtcat gatgaaattc ctgcatattt agctgatcat 68400
tatgatggat ggtcatcacg ccatacaatt aattgctact taaaattatg taaaacatta 68460
tttgaacgtt ttaaagggaa agtaaaatat tggttgacat ttaatgagct taatgttgta 68520
aagggttatg ctcaaatggg aactcataaa attgatagtc aaacgcatta tcaagcgatg 68580
catcatgttt ttgttgctag ttcattggca acaaaaatgg ctcatgaaat gatgccaggg 68640
tgcatggtag gaacaatgta tgcaatgagt ggtttatatc cattaacttg caagcctgag 68700
gacatgatgg cacatatgaa tactagaaga ttatcatatt tttatgcaga cactatggta 68760
actggcggat atccatatta tgcacaagca ttatttgaaa aagaaggggt cgtactggtt 68820
aaggagccag gtgatgatga tttactaaaa gaatatccac tagattttat tacttttagc 68880
tactatagaa caacaaccgt taatgctaac actaaattaa atattatcgg attagcaatg 68940
gatctaaatc cctatttaga agcaacccct tggggttggc caattgatcc tgttggattg 69000
cgctatgtta tgaatgaact ttatgatcgt tataaaaaac caattatgat tgttgaaaac 69060
ggaatgggtg aaatcgatca ttttgaaaat gatacagtta tagatgatta tcggatccga 69120
tatttaaaag atcattttaa aaacatgaaa gatgccatta atattgatca tgtagattgt 69180
attggttata cgatgtgggg ggctattgat cttgtttcac ttagtaccgg ggaaatgaaa 69240
aaacgttatg gttttgttta tgtagataaa aatgatgatg gtagcggaac atataatcga 69300
tataaaaaga aaagttttga ttggatgaaa gaagttattg caacaaatgg agaaaagata 69360
taaggaggga aataaaattc ccttttttta aattttaatc gggtctattt ataatttagg 69420
ttaatatatt taaaggagga atgattagga ggaatcatag atgtgtacag caataaagat 69480
atattcagat aatggagata tttattttgg tcgaacaatg gatttttcat ttgaattaaa 69540
tcctgaactt tattatattc ctgcaaaata ccagtggcgc aatgttctaa atactcatga 69600
tattgaaaat aagtacaata ttcttggtat cgggcaagat gtctctcctg ttgctttaag 69660
tgatggtgtt aatgaccatg gatttgcagt tgcggcatta tatttttctg ggtttgctca 69720
atatgatggg ctaaaaaaag ataatacatc aattatcccg atcgctgctt ttgaactagt 69780
ttatttttta ttaagtcaat gtgcttcagt aaaagaagct caagaattaa taaaagtcat 69840
caaaattatt ggtgtagaag atagtattac acatatagca gctcctcttc attggataat 69900
aagcggtgca aataacaatt gtatggtgat tgaaaaaaca atagatggtc tacatgcgat 69960
taataatcct attggtgttc ttgcaaatag tccagatttt tcttggcata tgactaattt 70020
atgaaattat tacaatttat cgccatatca atttcaagaa gcaatatgga acaatataaa 70080
acttactcca tttggacaag gtgcaggaac attaggctta ccaggggatt atacaccacc 70140
atcacgtttt attagagcag catttcaaaa aacatataca gatattccaa ttgatcgtca 70200
tcaagctgtg ataacttgtt ttcggatcat ggaaacggtc agtattccta aaggggtcgt 70260
cattacagca aatcaaactt ctgattatac tcaatatacg atgtttatta acttagcaac 70320
tcgagaatat tattttaaaa catattggaa taatcagata acaagagttg aatttcctca 70380
atatgatgaa aaagatatga aaatgctttc attaggaccg ttaaatcaaa cgattgaatt 70440
taaaactaga agtatttttt tataaaagga tgtgttgtta gatacatctt tttttgttta 70500
tatttatgat tattgtgaaa gaataaaata tgcttaagca tattcgttga agataatcga 70560
atgactatgc tagaatggca ttctaaggat gtgaaaaaaa tgttgataca aaaaagaaat 70620
ggtctttttc aagactatga taacaacaaa atagaaacag caataaaaaa agctttttgc 70680
agtttatctg aaacaataaa agatgatgaa ttaaaaaaga tgattgcaga tattgaaaaa 70740
catattatag ctgatatgtc tgttgaagca attcaagatt tggttgaaga aacattgatg 70800
aaacatggat atcttcaagt agcaaaagct tatattttat atcgtcaaaa gcatacggag 70860
cagcgattga taattgatga actgcttgcc ttattgggag atcaaaatct aaaaaaggtt 70920
ctattgaaga ttcacaaaga ctatcctcaa gaagaatatt cattgcaatt attattagtg 70980
aaatttaaaa cattttataa agagggtatg agtcattttg aagcgttgaa aatgttgatg 71040
aaagcgagtg tggaattaat tagtaaagaa gcacctaaat gggagatgat ttcagctcga 71100
tttttaactt atgatgtaaa tcaacaggtt gaccaaaaaa tgaataccgc tggtagatat 71160
actttttatg agcggattaa ctatttagca caacaaggtt attatggaca atatattctt 71220
gaaagctatt caaaagatga aatagacatg ttaggacagt atattagcga atcgcgaaat 71280
gaattattta catatagtgg tcttgaattg attgttaaaa gatacttgat tcaaaatcat 71340
gaccgcgaaa ttattgaaaa accacaggaa atgtttatgt caattgctat gcatttggcc 71400
atgaatgaat caaatagagt taagtgggca aaagagattt atgatatttt aagtacttta 71460
aaagtgacga tggcaacacc aactatgtct aatgcgagaa agccatttca tcaaatgagt 71520
tcatgtttta ttgatactgt cgatgattca ttagcaggaa tatataaaag tatagataat 71580
tttgctaaag tttcaaaaaa cggtggtgga atgggactgt attttggaaa agtacgtgct 71640
aatggaagta gtatcagagg tttcaaagga gcagcaggag gtgtgattcg atggcttaaa 71700
cttgtaaatg atactgcaac agcagtagat caattaggag ttcggcaggg agcagcagca 71760
gtatatttgg atgcatggca taaagatcta cccgaatttt tacaaattag aacaaataat 71820
ggcgatgatc gaatgaaagc acatgatatt tttcctgcgg tttgttatcc agatttattt 71880
tggaaattag ctaaaaatga tttggaagct tcatggtaca tgatgtgtcc acacgagata 71940
catgaagtta aaggttatta tttagaggat tgttatggtg aagagtggga aaggaaatat 72000
tatgagtgcg ttgaagatga ccgaattcct aaacgcgtta tgacagttaa agaaattgtt 72060
cgtttaatta ttaaatcact agttgaaaca ggaactcctt tcacatttaa tcgcgatcat 72120
gttaataatt ttaatcctaa tcctcatcag ggaatgatat attgcagtaa tctttgcaca 72180
gaaattgctc aaaatatgca agcgatggag atcttaccgt ctgaggaaat tgaggttaat 72240
ggtgaaacta ttattgttga aaaaacaaaa ccaggtgatt ttgtagtttg taatttagct 72300
tcattaacat taggtcatct tgatgtctta aatgatgatg aattgagaca cgttatcagt 72360
gttgtaatta gggctttgga caatgtaatt gatttaaatt attatccaat tccttttgcc 72420
aaaataacta atcaaaaata tcgtgcgatt ggattaggaa caagtggtta tcatcatatg 72480
ctggtaaaat tgaaaatgtc atttgaaagt gatgagcatt tacagtttat tgagcagctt 72540
tatgaaaaga ttaattactt tgcgttggaa gcttcatgtg atttagctaa agaaaaagga 72600
agttactcat tgtttaatgg tagtgatttt gaaacaggtg catactttat aaaacgtcgc 72660
tatcaaagta aagcatggca aaatcttcaa gctaaaatca aagaaaatgg tttaagaaat 72720
ggatatcttt tagcgattgc cccaaccagt tcaacttcaa ttattgctgg aacaacagca 72780
gcggttgatc ctatcatgaa aaagtatttt atggaagaga aaaagggaag tatgattact 72840
agagttgctc ccgacttaga ttctgaaact ttttggttat ataaaaatgc gcattatatt 72900
gatcaagagt ggattgttaa agcagcggga attaggcagc gtcatctcga ccagtcacaa 72960
tcagttaatt tatatatgac aaatgagttt acttttagaa agttgcttaa tttgtatatt 73020
aaagcttggg agtatggtgt taaaacatta tattatgtta gaagccagtc tttagaagtt 73080
gaagaatgtg aatcatgcag ttcataggag gtaataatgg aacttaaaca aaaagcatta 73140
tttaatgcta aaggtgatat tgatgtaaga aaacgtcgaa tgataaatgg aaatacaaca 73200
aatcttaatg attttaataa tatgaaatat cagtgggtca gtgattggta ccgtcaggcg 73260
atgaataatt tttggattcc agaagaaata aatttgactc aagatattag agattatcgt 73320
ttgttaagtg aggcagaacg aaccgcatat gataagattc tttcattttt agttttctta 73380
gattctttac agacagccaa tcttcctaat attggtgagt atattacagc aaatgaaatt 73440
aatctttgtt taaccattca agcatttcaa gaagcggtcc attcacaaag ttatagctat 73500
atgcttgatt caatttgttc accaactaaa cgagatgaaa ttttatatca atggaaattt 73560
gatgaacatt tgttgaagcg aaatgaattt attggtgaac agtataatgc atttcttgaa 73620
cataaagata gttttcattt aatgaaaacg attatggcta attatatttt ggaaggaatt 73680
tatttttatt caggatttat gttcttttat aatttagggc gaatgggtaa gatgtcggga 73740
tcagctcaag agattcgtta tattaatcgt gatgaaaata cacatttatg gttatttaga 73800
aatatgatta ttgagctgca aaaggaagaa ccgacattat ttacccctga aaagattgag 73860
gtttatcgta atatgctaaa acgtggagtt gaagaggaaa ttgcttgggg gcaatatgtc 73920
ttgggaaatc gaattgaggg tctaacgatg gatatggtca gtgattatat tcattatctc 73980
ggtaatttaa gagcattttc attgaatttt gaaccattat atgaaggatt tgagacagaa 74040
cctgaagcaa tgaaatgggt aagtatttat agtaatgcaa ataacattaa gaccgatttt 74100
tttgaagcaa aatctactgc ttatgcaaag tctagtgcta ttgaagatga tttatagaat 74160
atttagaaaa gcaagataga aaactacctt gcttttttga ttgatctatt gttcagctat 74220
ttgatgcata aacgtttatt agaggaggat atattgatgt atagaataaa aaaatccgtt 74280
attattttct tcgcttatcg catttattgt tagcctgatc tatttattaa tatctatagt 74340
aatagcagta tattataatc tatggaatgg tctattcctt cattcttatt gtaattcagt 74400
cgtttttgtg ttttgtttcc tgtgataatg atgagaaatt ttttatacac cgctatatat 74460
tttattttca aatattaatg tggatgtatc attggataat ttagctttgt cttcaccagt 74520
tgtctcgagc atgtacttaa atatcattat gatagcatca gtaggaatca tcggttatat 74580
aattttacag tctattcacc ttaataaaca gccaccttta attactgtct ttagtatttc 74640
agcgatgcat aggtgctatt ttaatgattt taattttatt ttgtcaaagc tccgatgcta 74700
ttattaaggc gtgaacatga agctattgtt aatcatcaat tatgtatcac taatactttt 74760
gaacaggttt ttaaagaaaa aatgctaaaa ctttataaaa aagttcggta tctttgtaat 74820
actcatggat atccttttac taaaaatatt cattcaaaat atcttgctga tttaatttat 74880
ctaaaaatga agcttctatg atacttttta ctgattatct atctggtaga cagtaagctt 74940
aaaaactgta ttgcaatgtg atatattaaa ctttgcctaa aaataataac tatgctagta 75000
atagtttatt tttttattat atatttgttt gacaagtcta acaccaggag ataagatata 75060
attgttggtt agattaggct aactattata attgttttaa ttgaaatatt tagcattaaa 75120
tcctatttta aaaagattat agagggtgtt gtgtggtgaa tcggatgatt ctattcgaaa 75180
aatcaatttg taagattgaa aaatgagaat tatccatatt gtgtgatgat ggaaattaat 75240
gggatgagtt gtaccgattg tcagcaacaa attgaaaatg agtttaatca gaagaaaatt 75300
tatttagaac agcatttggc tgtacttcta ccaaaacaag atgcaagtgt ggaatcagtc 75360
taggttttaa tagagatagt tggctatcgt gttattaaat taaaaaaatc tgaattaaaa 75420
gataggggga tttatatgta tttgcaatta gaaaatgtag aaaaatatta tggtgaaaat 75480
gaaaatcggg ttcaagtttt aaaaggggtc aatggttcaa tagaacgcgg tgaaatctgt 75540
gttatgctag gaccttcagg ctctggtaaa tcaacattat taaatttaat tggaggtatc 75600
gaaataattg attatggtaa tgtgatagtt ggtggaattg atttagcatc tttatcaaaa 75660
acaaaattag ggttataccg gcgggatact ttgggctttg ttttccaatt ttatcatcta 75720
gtcccaaatt taacagtaaa agaaaatatt gaaacaggtg catatttgag taagacacca 75780
ctagctgttg aaacactatt agataaatta ggattaaaag aacattgcaa taggtatcct 75840
aatcaattat caggaggaca gcagcaacga actgcaattg gtcgtgctct agcaaaaaat 75900
cctaaattat tattatgtga tgaaccgaca ggagctttag attatcatac atctaaagat 75960
attttagaat tattagaaca gattaatcag gattatggaa caactatttt aattgttact 76020
cataatgatg caattgctaa aatggcacat cgcgtgctgc gtttgcgaga tggacaaatt 76080
gtttcaaact atttaaatac atcacgaatc aatgctaaag agttagaatg gtagtagggt 76140
gttagcatga aaaatccatt aaataagagt ttaaaaaaag aattcactga taacttagct 76200
cgttatctag cacttgcttt ggtcatgata gttatgattg caactgtttc aggttttttt 76260
agtgtagctt atagtgttaa taatctatta aaacaaaatc aagatgaatg tttagtcgag 76320
gatggacagt ttactgtttt aaaaccattg actaaagaag taattaaaga aattgaaaaa 76380
gagcctgtaa aactttatga aaatttctat agcgagcaaa agatcaaaaa tagtgctaca 76440
ttaaggatat atcaagatcg tgaaaatatt aatttggtta cagtttacca agggaaactc 76500
ccaaaaaagc atcaagaaat agcattagat cggctttttg caataaaaaa tggttataaa 76560
ataaatgatc aaattaaggt caatggtata aagttaacta tcgttggata tttaagccta 76620
cctgactata gttcgttgat taaggataat agtgatttaa tgatggatcc tatccatttt 76680
ggagttgcta ttgtagatga gtcagatttt gctttattaa aagagaataa tattaattat 76740
acttatagtt ataaatcaaa tgatgattta agtagtaaag aaaattacga tcaattaaat 76800
caaattagag atatcgtagt tgatagtgga tgtagcttaa caggaatgat gacccaagag 76860
atgaaccagg caatatcatt tttacctaat gatatgggtg gtgatatccc aatgatgaat 76920
atgttgtttt atatcatttt ggttatttta gcctttattt ttgttgtaat ttcacaggcg 76980
ataattgaag accaagcaac tgcaattggc acattactag ctaatggtta tacaaaacaa 77040
gagttgattc accattatct tactttagta atgatcattg tttttgtaag tggactagtg 77100
ggaaatgtta ttggatatac aataatgcct tcattttttt ctaatatgta ctataacagt 77160
tattgcttgc caccattaca gttaaaattt attcctagtg tatttgttaa tactactgtg 77220
attccttttt tggttatttt gatagtcaat tatttaatgt tatggcataa attaaatatt 77280
tcgccattaa aatttttaag acaagatcta catgaaaata agaaaagtca ttatattcat 77340
ttaaagcaaa cgtcgtttat taagcgctat cgtcaaagag tgattcttca aaataaggga 77400
agttatttgg ttttaatgat tggaattatt tttgctagtt ttcttttaac ttttggtttt 77460
tgtattaccc cgtcgattga acgttattta gaaaatatgg aaaatagtat taaaacaaac 77520
taccaatatc ttttaaaggt accagttgaa gctgctggag aaaaaataac atatacatta 77580
ttacaaacct attttgctgc tggggaaatt gacttagatg tttcattcta tggattagat 77640
gataattcta tatattatgc ggatattgat ttgccaaagg aaaaagatca aattattatt 77700
tcctacgatt ttgctaaaaa agttggctta gaaaaaggag ataaagtaac gtttacaaac 77760
caatatactg aacaagaata tcagttaaag gtttttgata tttataatag ccgaactaat 77820
ataagtgttt atatgtcacg tgaatcatta aataatttac tcgaagaaga tctgaattat 77880
tataatagtt atttatcaga tcagaagtta aatattgata aaaaatatct tagtacgatg 77940
attactagga cagatatgct gaaaattggc gatcaaatga cggaaacctt ttcacagatg 78000
attccgatta tgagtgggat agcgatagtt atttatttag ttgtaatgta tattctaaca 78060
aaactagtat tagatcgaaa tactaattat atgtcgtttt taaaagtgat aggctataac 78120
agccaagaaa ttgctaagat atatcttaaa gctacagctt tggtagtagt attttcatta 78180
ttgattagtt taccaatttg taaatatggt ttagaaatat tgtttattca agcaatgatg 78240
agatttgcag gatatataga aatctatatt ccaacctacc tctatgtaat gatttttact 78300
gttggcttaa ttacttattt tgttgttaat tggctattga ataaacaaat tcaaagaatt 78360
gatttaggga aatctttaaa agaaacagaa taactatagg ttattctgtt ttcacctaaa 78420
aggaggagat tttaatgctt gaagatatta agctgccgtt tatagataaa aaggttatta 78480
ataagcatga aagagagtat caaataggtt taatcgatgg acagggagta atgacgagca 78540
tagatattta tccagggata caagttatat ataataattt tcattgtttt actgctccga 78600
ctgatcaatc tctcaatcgg catcgttata ttgaaattaa tcattgtcta aaaggtaaat 78660
ttgaatgtca gtataataaa aattattatg catatttatg tcaaggagat ttagcaatta 78720
gtggtggaac attaaataaa ttaactcact catttccatt gggttattat aatggtgtag 78780
aaattttgat tgaagtagaa aaagctaaag agaataaatt attagatgaa ttcaatattg 78840
atattgattt aatcagtaaa cgtttaaaag aaagccataa tgtatatatt tttcgtgcta 78900
ctgctcaaat tgaacatatt tgtttagaaa tgtatgagat agaagaggaa ttaaagagga 78960
attacctaaa aataaaagtg ttagaactgt tattattttt atcacatcat gactttggaa 79020
ttttagaaaa tgaaaagcat tattatccaa aaaaacaaat tgagattatc aaggcaataa 79080
aaacagagct tagtaacaat atttcagcta aatatgatct tgaaaaacta gtaaaacaat 79140
acaatattaa tattcataca tttcgtaaag catttaaaga gattcacggt aaaccaatct 79200
atcagtggta taaagaatat cgtttagagt atagtttagg tctactgatt aataccgata 79260
ttccaattat cgaaatagct aatgagattg gttattctaa tccaagtaaa tattcagctg 79320
cattttatca atatacttct atgacacccc agcaatatcg taaatcacat cttaaaatgg 79380
agcaataata acaaaatgga gtagcagtaa taatatttag gagttatact ctcttataaa 79440
gttagtctat tctaactaaa ggagggttaa tatgacagta ttaaaatctt tatttgctta 79500
tgctggcaaa tataaatatt taacaatact ttctttagta ttttcaatga taagtgctat 79560
tttattatta atgccattta ttatgatttg gaaagttatt gaggttattt tggcagagta 79620
tccaaacttt gcccaaggaa gtattgcgat acaatacggc tggtacgcgt taatttttgc 79680
tgcagttgga attttattgt atgtttcggg cttactttgc tcacatttag ctgcatttag 79740
aattgcttca aatatgcgta aaaaagcttt acatcatgct gttcaattac cacttggata 79800
ttttgctaaa gaaggaagtg gtaaattaag aaaaattatt gatgaagctg cagcttcaac 79860
agaaacttat ttagcacatc aattaccgga tatggcacaa ttgattacta ctgtttgtgc 79920
ggtaatagtc tgtttattta tttttgattg gaagtttggg atagctgcac taattccaac 79980
gattttagca ctatcaaata tgtttaaaat gattggtcct ggcttacagg aatcaatgaa 80040
agcatatatg gatgcacttg aaggaatgag taatgaagca gttgaataca ttcgtgggat 80100
acctgttgtt aaaacatttc aacagacagt tttttctttt gatcgttttc atcaatcaat 80160
taataattat gaaaaatttg caattggtta tacaaataag atgcgtttcc caatgacttt 80220
gtttacgacc ttcatcaata gtattttcat tttcattatt ggcacaatga tgttattgat 80280
cttaaacggt tttgatttaa attctttaat gccagatttc ttattttatg ttatttttac 80340
accaattatt gcagtaacaa ctaataaaat tatgtttgca agtgaaaata caatgatggc 80400
tgcagatgct ttaaaccgaa tcgaaggaat tattaatcaa aagccgttta cgtataagca 80460
tagtctgcaa gaaatcacca atagtgatat cgaatttgag catgtctctt ttacttatcc 80520
agaaagtgaa aatgaagtca ttcatgatgt taatttgaaa ataaaaagtg gttctattgt 80580
tgcttttgtt ggtaaaagtg gaggtggtaa atcaacgcta gtatccctaa taccgagatt 80640
ttatgatgtg actaaaggga ctattaaaat tggtggtgtc gatgttaaag aaattagtga 80700
aaaagaatta atgagtaaga tttcattcgt atttcaagac agtcgtcttt taaagaaaag 80760
ttttaaagaa aatattaaga tgggatcaaa tgcaagtgtt gaagatattc agacggcagt 80820
tcataaagct caatgtgatg atattataga gaaatttgat caaggattag aaactaagat 80880
tggtagtaaa ggggtttatt tatcaggtgg ggaaacccaa agactgacat tagcacgagc 80940
cattgttaaa gatgctccaa ttttgttatt agatgaggct actgcttacg ctgatagtga 81000
taatgaagtc ttaatgcaaa aagcaattat ggaattagca aaagacaaga ctacgattat 81060
gattgctcat cgactttcaa caattgtaaa tgttgactgt atctatgttg ttgataatgg 81120
tgaaattatt gagagcggaa cgcatcaaga attattaatt aaaaacggat tatatgctca 81180
aatgtggcat caatattgtc agtcagtaga atggaaagta ggtgaacaag aatgataaaa 81240
aaggttcaag agcgttttgc tttaacccat ttgggagcag ttaatttaat taaggcttgt 81300
gtttcatgta cgatatcata tttagcaatc gcaatgtcaa ttggagtgtt atattatttt 81360
acttgtgatg ttttagaaat gctatatggc agttcaaata caatcttata ttcaatgtat 81420
ctgattgaat ttgtaatagt tgttatctta atttttatcg ctcactatat tcaatataat 81480
atgacttttt ataatactta taaagaaagt gcaagattaa ggattcgtgt tgctgaaaaa 81540
cttcgaaaat tcccgttaat gtttttttca aaacgtgatt tatcagattt aacaacaaca 81600
attttgtctg atgttacggg aatggaacag gctctatcac attttattcc tgaattcttt 81660
gggtcaatag cttccacact tttactatct atatcgatgt tctttttcga ctttaggatg 81720
gctttagcag ctgtttggtg tgttcctgta tcatttttat tagtagttct ggctaaacga 81780
aaattaagta atgctggatt taaagatcgt caaaaacaat tagttcgaac tgaaaagatt 81840
caagagacgc tggagacaat tagggattta aaagctaatc actatactca gcagtatctt 81900
aatgaggtag atcaagttat tgatgattgt gaaaagagtc aaattaaaac agaacttaca 81960
aatgctttat ttgtagttag ttcacaattg attttaaaat taggaattgc aacagtagtc 82020
atttatggag taacatcact aatcaatcaa atgattgatc tgaaagtctt tatgttattt 82080
ttaattgttg cttctcgtct ttatgatcct cttagtggga cattacaaaa cttagcagcg 82140
attatcagtt gcgatcctaa aattgctcgt ctaaatgaaa tagaaaatta tccccttcaa 82200
actggtgaag aaaaatttga accaagtaac tatgatattg aatttaaaaa tgtaagtttt 82260
gagtaccaat ctgaaaaaaa ggtacttgaa gatgtaagtt ttgttgctaa acaaaatgaa 82320
attacggctt taattggaaa tagtggtggc ggtaaaacaa cctgtgcttc attagctgct 82380
cgtttttatg aattaaacga aggggttatt aaaataggtg gaattgatat ttctacagtt 82440
gatcccgaaa tactattatc aaaattttct attgtttttc aagaggttgt tttatttaat 82500
aatactattt tagaaaatat tcgcattggt aaaaaagatg caactgacga agaagtcatg 82560
gaagcagctc aaaaagcttt ttgtgatgag tttgttgaaa aactgccaga tggatataat 82620
acggttattg gtgaaaatgg ttcaaaatta tcaggtgggc aacggcagcg aatttcaata 82680
gctcgagcaa ttcttaaaga tgcacctatt attttattag atgaagcaag tgcttcattg 82740
gatgttgaaa gtgagacctt tgtacaaaaa gcgttatcac gtttgattgc taatcgaacc 82800
gtcattatga ttgctcaccg gatgaggacg attgctaatg cctctaagtt gattatttta 82860
gaagatggac atgtagttga gcaaggaact ccagaacaat tattacgtaa agaaggggtt 82920
tatcaaagaa tggttgacct gcaaaaaatg agtaacgagt ggaaattata aaaactagca 82980
agatattgct ggtttttttg ttagatttat ataactttag attgactatg acgaaaaaaa 83040
gagtattcta atagtatagg gtgttagttt tgactaacat ctttataata agttaggagg 83100
aacattaatg aaagatttat taaaaaacaa aactgtatta tcctttgtag gaggaattgc 83160
agcaacgatt gctggtgcaa agtttttaaa aagcgataaa gctagaacaa tggcggttaa 83220
ttctttagct tcgggaatga agctaaaaga cgatgcgatg gctacttatg aaacgatcaa 83280
ggaagatgca aaagatattt gttacgaagc aaaagctaaa aatgagggag aatagatagg 83340
ttatgaaagc ttatcaaatt gttcatgata tgcctggacg aatgcgaatt cgttatggta 83400
aatatacttt ttcaaaaact gcagcaattg gattaagcta tgaattagaa cgttggaaaa 83460
tggttaataa ggtcgaagct aatgatataa caggaagtat tttatttatt tatgataaaa 83520
atagaagaag agaattatta gctttaatac gacaatttga aatagaaaaa tttgatgtaa 83580
caccatatct agcgacaatc aaggagtata attcttatga aataacacaa aaagaagtta 83640
gccaaaatta tacttctaaa tttataaagt tattgcttcg ccgttattca attcggtggt 83700
ttttaccaac tccgatacaa tatttaagca gtatcgtttt agcggttaaa tatttcaaaa 83760
aggggctagc ttcattaggt aaaggacata ttgatgtgcc agttcttgat gcgacaagta 83820
tcgctgtatc gatgcttaat agacagttta aaacagctgg cgatattatg tttttattgt 83880
cggtatcaca attattagaa gactatacaa gaaaaaaaac aactttacaa ttaaaagaat 83940
cattatcact tcatctagat aaggtttgga tcttagaaaa tgagtcagaa atagaaattc 84000
ctagtgatac tctaaaaaga ggtgatatag ttattgttca catggggacg atgatccctg 84060
ttgatggaga aataaccgat ggtcaggctt tgatcaatga atcaagtttt actggtgagc 84120
ctctaagtaa agcggttggt aaggatgata ctgtttttgc aggaacaatt gtagaagaag 84180
gaaaaattta tgtaaaagtt agaaatctac aaaaagaaag tcgtattaat aaaattgttg 84240
atatgatcga tgttaatgaa acattaaaag ctggtgttca atcgcgagct gaacatcttg 84300
ctgattcgat tgttccattt agtttttttg gcttctttgg attgctatta tggacaagaa 84360
gtctaacaag agcgacttca attttattag ttgattattc gtgtgcaatt aaattgacta 84420
catcaatttc tatcatcagt gcaatgcaag aggctggaaa acattcaatc atggttaaag 84480
gtggtaaata tcttgaagcg atggctcaag ccgatacaat tgtctttgat aaaacaggaa 84540
ctttaactaa tgcgactcca ttcgttcaag aagtaacacc actagatgac tacagtcgtg 84600
atgaagtact tagaattgca gcttgtcttg aagaacattt ccctcacagt gttgctaacg 84660
caattgttaa gcaagcccaa gatgaggaat tgttacatca agaagaacat gctgaagtag 84720
aatatattat tgctcatggt attgctacta atttacatgg tcaaagagca attattggta 84780
gtgagcattt tgtttttgat gatgaacaga ttgaaaaacc ccctgaaata gttcagttga 84840
tcagcaaatt acatagtaaa ggagctagtt cattgattta tttagcaata ggtcaacgcc 84900
tagcaggaat cattagtatt tatgatccgc tcaagccgga agccaagcat gtaattaata 84960
atttacggga gattggtttt aaaaaggtta ttatgttaac tggagattgt gaaaacgctg 85020
cagggcatat tgcaaatgaa ctaggaatag atgattataa agctggtatt ttaccagaag 85080
ataaagctga gtatataaga cggttaaaag cgaaaggtaa aaaagtcgtg atggtgggtg 85140
atggcgtaaa tgatactccg gcactatcaa gtgcagatgt atctatttca atgcaagata 85200
gttccgatat tgcccgtgaa ctagcagatg tgacattgac ttcaagtcgt ttggatgaaa 85260
ttgttgaatt taaaaagatt tcgatattac taatgcaaag aataaaacat aattatacta 85320
atatcgtggc atttaatagt ttattaattt tatctggact aattggatta ttacagccta 85380
atacaagtgc atttttacac aatacttcaa cattcctatt ttctgctgtc tcaacaaaac 85440
cgcttcttta taaaaaagaa aattaagcaa gtagggagat ttccttactt gcttttataa 85500
tcaattgaat tataagataa ataaatgtct atactataaa aaattaataa atttaaggga 85560
gaagtggtta tgggagaagc actggaagat tatttagaag ctattttaat tttatctaat 85620
caaaataaag ccgttcgttc tgttgattta gcagtgtatc gaggatattc tagggcaagt 85680
attagttatg cagttaaaga gcttagaaat aaaaattatt tagaagtaaa taaagatggt 85740
catctcaagt taacatcgag tggtcaagta cttgctaata gaatttatga acgacactgt 85800
ttttttaaaa aacttttaat cgctgctggc gtaagttcaa accaagcaga aatagaagct 85860
tgtaaaatgg aacatggaat tagtgatgac agttttgaaa agttgaaaac gttgttagat 85920
ttttagcatg gaatttttgt ttgagtataa acatagatat tgtaaaaatt gattgaatag 85980
aaatttatta aaaaaatgct gttaatatgt tttaaaataa aaagacaaaa tcaaatattt 86040
ttggttttga ttttatccgt tcatttatct gaattttaat ggtatatatt tttataagaa 86100
aatttcgtta tttgctgatt tcagcataaa tgtgtaattg atgtagagaa tgaatataat 86160
cattaagcac atgtaatctt agttgtgtat caactggtaa tgataaaaaa tattcgcgag 86220
aactagaact gcgctggatt aattcatgta agttttgata tttaatgtca ctcacctcta 86280
aacatatcat agccgttatt gataaaaata tacaggttca aaaacataat gatttaattg 86340
cataaaatag aaaaggaaat acaagcatat taaaattgca cgttgctaga aacattcata 86400
cgtaacaaat gtattttaaa ttatccttta ttatctataa taaaaaagag aaaaaaataa 86460
aggtgattat aaaattaata aggaaaagta tttcaatagc tatgcggttg aatccaaatt 86520
ggataatact gtttaatagt agaaagaata atggagctat aaaatcaaca acagctgcaa 86580
agtcatgaat tattgcttca atcgtatctg ggtcttttgt taatactaaa gcattcagac 86640
aggagctcgc ctccaaagga taatatcatg atggataaca ccattagcga tacaatagga 86700
aatgagaaag attttaaaat gataaaaaat ctaatggtaa tataactaag aaaaattcta 86760
agccaaatca gctaaaaatt ataaattctt tttacagggt ctttagaatt ttctaatata 86820
ccttattatc ataaatctac ttttacagct agaataaaat gattttaaga tttctggtaa 86880
taaaaattca ccaaaatcat tattaaaaga atcaactaag taaattgatg tataggtagt 86940
ttttcataat aactcatcac tttatttaat aattatatta ttttgttgat taacttaata 87000
aacaataaaa acatgacata agtcatgttt ttattggctc cagcctttgg tattattacg 87060
gacattgata aaatcttggt atattccagt ttgtttgatt aactggttat ggcttccgct 87120
ttgtgcaatt tttccatcag ctatgacaag aatcttatct gcgtagcgaa tagtgtttaa 87180
acgatgtgct attactaata aggtttttcc ttgacataac tgtgtaattg cttcttggat 87240
ataattttcg ttatcaccat caatactgga agttgcttca tcaaggataa taataggagc 87300
atcttttaaa atacatcgag caattgaaat tcgttgtttt tcaccaccgg aaaggcttgt 87360
accaccttcc ccaataattg tttgaaaacc atttggcagt gccatgataa aatcataaca 87420
ccgagctttt ttagctgctt caatgacttc tttttccgta gcctcaagtc gtccgatgct 87480
aatattatta tagatagtat cctgaaataa ataaacacgt tggaaaacca tactgatatg 87540
attcattaaa tcagcaagtt taacgttttt gatatttgtt ccacggatgt ttattgaccc 87600
gctatcaacg tcccaaaaac gtgttaatag attagcaatc gtacttttac cgcctcctga 87660
tggacccaca agagcaagca tcttattttt ttctaatgta aaatttatat tgtgtaatac 87720
ttctttttta tcataagaga aactaacatt tttaaatttt atttctggta gatcactttg 87780
ttctggaatt acttccatac catcatcagg cagttctttt tgagctaaga catcttcgac 87840
acgatccata caactactca ttacagttaa ccgtgtactt tgactataca acgctttaag 87900
tggaccaaat aagtcaaata caaataaagt tactccaatc aagtaaggaa cagttagtaa 87960
attttgagtt tgtagatata atgagagtgc taaaatagca gctattccta aaccataaat 88020
aatatttagc caacgttgcc agggagcatg tgtttcttca aattctaaat tagttcggca 88080
gctctcttta aaattattag aaagttcagc tgatttttca cctaacagat tataagtttt 88140
aataatacta ataccctcaa taaaatcaag tacagcatta gtgagttttt cactttgttc 88200
ttgtctgata gttgaatgtt ctaatgtttg ttgttccatc gctttaccta accataggat 88260
tgctccagca attaacaatg aaagtatccc caaccaaata tttaaataga acataaagat 88320
gatcataata atttcagcaa aaatatagct catcatgtca gcaatcacgg tcatacaatt 88380
ttcttctata aagaccatat ccgtagataa tactgaacta attttcccaa tatttccttc 88440
agtaaagtaa cccattggca attttctaag atgacggcct aattccatgc gcatatctga 88500
aaaaattcga taaccagaat caccttgtaa acgatcagaa atattttgaa aaactgcttg 88560
aaataaaaca caaactatta atgtaatacc aagcagaaaa cataatcgat cagacatttt 88620
attattataa aaagcattaa aagcaataaa tgctagtccg attggggatt ttgctaacat 88680
tgattttaaa aacgagaaaa taaaagcgat tttaatattg cgacgatatt ttccggcgat 88740
agcaaggatt cgtgacatta atgagatcat aattaattac ctccttgatt atgactaact 88800
ctccaattag cactattatt tgccatggtc cataactttt ggtattcaag gcaagtatct 88860
ataagttctt gatgagttcc tactgcgttt aaatagccat ttttaagtac acaaatctga 88920
tgtgcattga taattgaatg tagatggtgg gcaataacaa taacagtttt atctttgata 88980
acttctgcaa ttgcggcatt cattttttct tcattttctg gatccataaa tgcagtagct 89040
tcatcaagaa caatgattgg agcatctttg agaattgccc gagcaagaga aattctttgt 89100
cgttcaccac cggataattg ttttcctcca tcacctgcca aagtatgaat tcctaattca 89160
agacggctta aaaattcatc acactgtgct ttactagctg cttgataaac ttcttcatca 89220
ctagcatcaa gccgtcccat tctaatattt tccatcaaag ttgtattaaa tagaaattgt 89280
tcttgtgata cataggcaat ttgattattt aacgtttcaa tgctcatttg tcgtaaatct 89340
tgatttccaa ttttgatcga acctgaatgg acatcataaa aatgaacaag cagttttgct 89400
aatgtgcttt ttccacttcc agattcccca atcaaagccg ttagtgagcc ttctttaatt 89460
tctaagttaa tattatgtaa aactacatta ttattgtatg caaaactaac attatcaaag 89520
ctgatatgat ggtttctgtc tttaaaacaa tcagatgttt gttgtagtgg cggtgcactt 89580
aacatttttt caagagactc aattttataa ctgatttgtg gtaaagttga gacaaacgcc 89640
aaagcccgta aaagcggagt accaattgcg aatgataagc aaagaataag aactaagtca 89700
ggtaaactcg aatagttgtg aagaactaac caagatccaa atggtagagt aagtaaagct 89760
acacatggta aaatactatt atagagtgcc atccatggcc aacaagcttt gtaccaggca 89820
agagtgaaat cacgatatcc acgtatatca ttttcaaaac gatgatatga ttcaccatcg 89880
cgattgaata ctttaacaac ttccattcca ttaacatatt caataatagt attattcatt 89940
ttttgtgcag atgcgtagta attactcatt tctttcatac caattttgaa cattgccccc 90000
atcgctaata aaccaatggg aagagaacct aaagataata aggcaagttt ccaatcaaca 90060
ataaacataa caatatagat gaagagggga atagctaagt tcgagatccc ttccggcaaa 90120
gcatgtgcca atagtagttc aattgcttca atatcatcaa taaaagtttt tttatgagct 90180
ccaactcctt tttcttgaat aactcctaat ggttgctttt caagtttgca ttgtaaagaa 90240
attcgtagat tttttaatgt gtgatatgca ctttggtgtg ataaggcaag acctttaaca 90300
taaaaaacgg catataagat aagtgaaatt gcaatggcaa taactctaaa aataatataa 90360
tgagtgctta tttgctgatg catgattaaa ggtgtaataa tttgatagat aaaaagaaat 90420
ggtaagatat tcattcctac tccaatcagc attgtggcaa tagcttgata agtttttttt 90480
cgataatcac cagcgtattc taatactttt ttaagcatgt aatcccttct ttctggttag 90540
ttttagctaa cctaagtttt ttttaaaact cccatctagg gagtttaacg tgtatatcca 90600
agaacttggt accagttaaa gaaatggcag acaatttggc aatgattctc tatttgctcc 90660
caactaaaac catggatgaa tggctcatag atcgtagtcc aaaaagaaga tagtagagta 90720
tgaaattccg ttttactgat ttccgtagta aaaattcctc gatttttagc ttcaagataa 90780
tattcataag tatagatgga cattttttca acccagtcgt gagtaaaatt agaaaaggaa 90840
gtaccttgtg agcatgatag taatagaata aagccatcat aatggctata taaaaattta 90900
aaccaccata acattacatc gttattcata ttccaggctt caattaattc aaattctgta 90960
actgtttcaa aattgatcct acggttgtca gcgacttcat ttaaagcttc taaagtaggg 91020
gtaactactg ctgtaaataa ttcctcttta cttttatagc gtttgtaaag tgcccctgta 91080
gtaacctttg catttgcaca gattgttttc aaagaagctt tctcataacc ttgtgataaa 91140
aattcttctt tagcactttt taaaattctt ggatcaatag atttatcggg ttttgacaat 91200
ttatcgcctc cttttatact gataattaaa ttatcgataa tctaattatc agtataaaag 91260
taattgcact tgatgtcaat cgttacaata aaattttagg ttgaaagtaa taaatttgtt 91320
tttataaaaa tttaattgga ataaataaaa aagccaactt ttgaataatg tataagttga 91380
ctttttgagg attatttaat ttagaggtat ttcaagtata tgtgctttat tgatgataac 91440
gctttaaaag aatttttttt aaataagctt taatatagaa aattaaactt agcaataatg 91500
ctaaaaggat caatgtttca atcataatta aacagtaact agttttttac cctgatcagc 91560
aacagcatcg atcttctctt ttaataacgt ttcatcacct aaatagtaat gttttattac 91620
tttaaattca tcatcaaatt catatactaa aggaattcca gttggaatat taatattcat 91680
gattgcttcg ttacttaact tatcaaagta tttaaccaac gctcttaatg aattaccatg 91740
tgcaacaatt aaggctcgtt taccagcctg catatctttt tttactgttt cattaaaata 91800
aggaataacc cgctcaattg ttgtttttaa gctctcacct gctggtaaaa gagcagagtc 91860
aatatttcga tacattgcct gcttttgcgc gctgcgttta tcatttatat ttaaagctgg 91920
tggcagtaca tcaaatgaac gacgccaaat tttcacctgt tcttcaccgt atttttctgc 91980
agtttccgct ttatttaatc cttgtaaagc accataatga cgttcgttta gtttccagct 92040
tttattgaca ggcagccagc agagatccat ttcatctaat atatgattta atgtgtgaat 92100
ggctcttttc agataagaag tgtagcatac atcaaattca taaccttcat tttttaaaat 92160
cgtgcctgct tgtattgctt ctcgatggcc agtttggctt aaatctacat ctgtccatcc 92220
tgtaaaaaga tttaatttat tccagtcact ttctccatga cgtactaata ctagtttcat 92280
aatatctctc cttttagtta gcttaagcta actatatttg tataatattc caatgaacaa 92340
aatttgtcaa ctaagatgat aataaaagca agctgttaca atatttttca caaaagaatt 92400
aatctgattt tactgactga aaagattaag atttcatttg aaatgatttt tagttataat 92460
aattttatag gcttgagaag ttagagagtg agggaatggt tatagtaaca gcaagcactg 92520
atgtggcttt ttgattatca atgaaaatat atataaaaat atgataatat tttagtaaca 92580
ttggaaataa aaatgccggt atcgattaat attgatgaaa gcgacttttc aacttttgaa 92640
aatgctggat ttaatattaa aaataatgat atattagaaa taatgaaagc gatttaatga 92700
ggtaggaaaa tgagtagagt aaaaagttta aatatcaagt atgtagccag tcaagtattt 92760
tattttgcaa cctttgccgc aatgatggga tatgcctcag tatacctatt gcacaaaggt 92820
tttagtaatt caacaattgg tataattttg tccctatgca atattttagc ggtgttcatg 92880
caaccggcat tagcaacttt tgctgataag aatcaaaaga ttgaaattcg taaaattatt 92940
acaactatcg ttgcaatagc aattgcttta tctgcaattt tattagtagt tccaagtaat 93000
caggcaatta tttttatttt gattgtatca atcttttcat taatgacaac gataatgccg 93060
ctaatgaata ctttggcatt tgtttttgaa aagtatggaa ttcaagtgaa ttatggcttg 93120
gctcgagggc tggggtctgt tgcttacgct gttgcatcaa tggtattagg acatgcagtt 93180
gatgctttta gtccggattt attaccagta tgttatgttg tctttaatgc actattattt 93240
attgttgttc atggctatgt attgccaaaa agtgaacaaa tcgaagttgc agttgagaca 93300
aatgacgagg atgaagttgc agtaaataat gaaggtttgc taagatttgc tggtaaatat 93360
aaaaaattta ttgtattttt attagggttt gtttttgttt attttgccca tacaattatt 93420
aataatttct ttatccaaat aattactaat gtaggcggta atagtagtga tatgggaaat 93480
gctgtatttt tagcagcgat gttagaatta ccgacaatgg catattttac gaagcttagt 93540
aaaaaagtta attgtggaac gttaattaaa atttctatta ttctattctt agtaaaacat 93600
gtgattactt attttgcaga tggaatgaca atgatctata tagctcaagc tttccaaatg 93660
ggggcttatg ctttatttat tccggcatct gtttattatg tgaattgtaa aattgcccca 93720
caagatatgg ttaaaggtca atcatttgtg actacttcaa tgacagtagc aggggttttt 93780
ggtaacttga ttggtgggat gttactagat tcagttggtg ttagccaagt actgttaatt 93840
agtgctgttc tatcattaat aggtgcggta attgtagtaa tgtctgttga aaaagtataa 93900
ttttatagaa ttaatgaaag tgtcggttta gttatttaaa atggtgcttt aaaataatat 93960
agggtactaa acaaaaagct ttaacaaaaa gtagggttag aagatgtata atcttcaata 94020
attatcctac ttttttatgt ctagatatag tattatttca ttttttattt gtttttgttt 94080
ttcttgattt gttttttatt aatagaaatt gtatacgtat ctaaaagatt ctgagaatac 94140
ataattctat ttctagctct gtcaaaattg gtcattccat ttacattaga tagaatcttt 94200
tttacataat tattttttcc ttcaatacat ccgttagata ttcttcttca ttatattcat 94260
tttctttaac atcattaaat acacgataat cttcttttaa attataagcc atttttaatt 94320
ctttgtttat agaaagaaca cattctaata ctcctgcttc actagttgta taacctaatg 94380
tacgatcaaa aaagtacttt tcatcattta ttttatcgcc actctttaaa agcagttcgt 94440
atctatattt taataatttg tattcttgac tatctttgta acgtcttaat atccttttcc 94500
taactgaatt tagacaatct gtaatcttct ttaaaatatg gaaactgtca atacatatta 94560
tagctttagg aaaatatagt ctcattaaag tgcggtaatg attatacata tccatagaaa 94620
tgtattttac tttatcacgt tcactcttag gaatggagaa gaaataatca ttaagtttct 94680
cttcacatct agattcaacg atatctagga taagttagtt tttgaatccc ataatcataa 94740
atgcatattt atatttagaa cgtctgtcga aatagaaatc atctatacat atgatttctt 94800
gtaagtggtg tctttttaat tgaacatgat tatcaaatat tcttactact gttgaagggc 94860
taacgttata gcatttggca atagatgagt aagtagctgt ataatgttta agatcattta 94920
atatagaaat taatgtaaca tttgtaatag aactataact cttatcaaaa gaatttggtt 94980
cattaaatgt tttccttcag taaggacata tcattcttct taattcgtaa ttaatatatg 95040
tatcagtagc atttatgatt tgataaacat attttctttt tttatattct tttactttag 95100
aagttagttt aagacattga ggacatctgc aaggttatcc attaagatgt acatataaca 95160
atatttgtgg ttgagtttct tactgtctca atgttctcta cctcttcttg ttttaaatct 95220
aataaattaa tgataaaatt tttgataagg gcttctctgg ttatacttat atctagacaa 95280
aataattata acaaggaacc cttttaatgt tgaaaaaacc tacttatgtt aaagcaagaa 95340
aatgaaaaac cctacaaaat tttgttatac ctttaaaatg ctagatcaac actgtttata 95400
tagaaaaata aattttattt taataatata aaataaaatc taattaatac ttaagttact 95460
ttgatattta tgttagaatc ttaatattgc gaataggagg aaatatatga gtaaagtaat 95520
taagttaggc aattataaag gaatcgaggc agaagtaaca aaacaacctg ttgctgatac 95580
agaggtagat aatgagattc aacgtttagt tgctcaaagt acaagtctaa tcgaaaaaga 95640
tggtgatgtt actaatggcg atgtaacaac tattgatttt gaaggtttta aagatgaagt 95700
tgcttttgat ggtggaaaag ctgaaggttt tcaactagaa atcgggtctg gtcaatttat 95760
tcctggattt gaagaacaaa tgattgggat gaaaaaaggt gaaacaagag aattaaattt 95820
aacttttcca gaaaattatg gagctgcaga tcttgctgga gcagatgttg tttttaaggt 95880
aactgttcat aaaattgaag agaaaaaaga agctgagtta aatgatgcgt ttgtagcatc 95940
actaaatgca cctggaatcg aaacgattga tcaattgcgc gataatataa aagcatcttt 96000
agaagcccaa catgaacagg catttatggc tgctaaagaa aatgcagcat taggaaaatt 96060
aattgatgac tgtgaagtag aagtagagga aagtgatatt gaaaaagcgc tgcaacaaca 96120
acttcaacat atcagtatgg aacttgctag tcaaggaatg caattagaac aatatttaca 96180
aatgatggga atgaatcaag agacattatt acaacaatta gcaccttcag ctaaacaaca 96240
agcaactttt gaagccatta ttgatgaaat tgtggcgatt gaaaatttag agactagtga 96300
tgaagaagca aatcaacaag tagaagcaat tgccgcacat aatcaagtgt ctaaagaaga 96360
tgttttaaat caaattgata ttgaaagttt gaaacgtgat ttaaatagaa ttaaagcaag 96420
ccgattaatt atggataaca ctgtttttat tgaagtataa tagaaagaat tattgatatc 96480
tttattaaga tatcataatt ctttttttat aataagtatg aagattgtac agttacttaa 96540
tccaagatga aaaataattg ttataattag aaaaagttga taatttaaat cgagggttat 96600
atgaaaaaaa ttttaattag tattatttta tgtggatgta aaacagctgt gagtcgagaa 96660
attaaaacag aaacacgata taatcaaatt gaaatcaatg cagctatgga tgaaattgaa 96720
atggaatttg caaattgcac cttattggaa ttatcttttg atgaaacaaa tgagcaaaat 96780
caaaattttg atagtgggaa aattattgtt tatggtaaaa tcaaggttga cgagacaatt 96840
ggtatcgaaa atttagagat taacagtatt tgtgataaat tttttttaat tttggaagtt 96900
aacatgcatg gtgagtggaa aatagcaagc tatggatgtt gaattctagg aactagaagt 96960
atttaggaaa gtaaaaacga taataaagga ggaattgatg atgcaacgtg gtattttaat 97020
tacgggtggc gctcatggga ttggaaaaca aatttgtttg gattttttaa ggcaagggga 97080
taaagtatgt ttcatagata ttaatgaaga ggcatcaaaa cgctttgaaa gtgaatatca 97140
tgatttatac tattattacg gtgatgtagc aaatccagat acattgaaaa attatgttga 97200
ttttgctaaa aaaaggttag gacgaattga tgtattagtt aataatgcct gtaaagggat 97260
gaggggaata ttatcggata ttgattataa tacttttgat tatgtacttt caataggttt 97320
aaaagcccct tatgaattaa gtcgattgtg taaagaagaa ttaattaaaa ataaaggaaa 97380
gattattaat attgcttctt cacgagcgtt tcagtcagag cccgatagtg aggcatatgc 97440
cagtgcaaaa ggtggaatcg tagctttaac acatgcatta gcgatatcac tgggtcctga 97500
cgtattagtt aattgtattg ctcccggatg gatcaatgtt gatgaaatag aaaattttgg 97560
tgaacttgat aaggcttctc taccggctgg gaaagtagga acaccaaagg atatttctaa 97620
aatggtttta tttttatgtg ggcaagattt tattaccgga gaaacgatta cgattgatgg 97680
cggaatgaac aaacggatga tttatcatgg tgactggaat tggcaatatc atgaagaata 97740
aaaaatagta gtatactaat ttttgttatt ttaattttaa agctaaatat aaaatattag 97800
catcacgaaa ttttcgtgga ttataaccac ataatttatg gatacgatct aatttatact 97860
gtaatgtatt tttatggata aaaagacgat tagcagtatt taataaggac atatcctctt 97920
caaaatatat gtgtaataaa tttaaatctt ctaatgataa cattgcaatt gttttattta 97980
gatagtcttt tttgtcataa atggatattg attgaagaat aatttcaagt gttaacacat 98040
catagttaat atattgatgg tcttgaatat ttcttagagc aattaaggca gaatgataag 98100
attcactaag ttttattaaa ggaatttgtt taccaacagc tattgaaacc tgattaccgg 98160
caagtttttt gagcttatat tcacatctat taaagtaatc agcatctatt attgctagaa 98220
aacgattggg gtactgatag tgatataccg gaatggctaa gctatgaagt tcttggataa 98280
tagactgctc atttacgagc cgttttgcta aaataatcaa aagacgataa ttgtttttta 98340
aatctaactg aaaatatttt aacatatctg aaaaatattg ggagtcaagg ttttcttggt 98400
ccagtaatga ttgtaacaga taatgcattt tttcagcctg gctacgatta aattcattca 98460
gctctttttc tcgaattaat agatttgtga ttttttgtgc taaataggca tattttttta 98520
ctttatcagg tttaccactg attccaataa cagcaataat ttgatcgtgg taatagactg 98580
gtaaattaac tccctgaaga ctaccattaa aactagtatc atcatacact tcgataattc 98640
ttttctcctt gatggctaaa agaccagctt catggaagga accaattctt tttatatctg 98700
tactggcata gataattcct tgacaatcaa taaaattaat atcgtggtca caaatatctt 98760
taactgtttc aacgatttga gtagctaatt ggttattaat atacatataa tcctcctttg 98820
gtataagtac taaataaata tgcattttat ttaaataaca tgttaattat aacatattat 98880
ttataaaaat aatttgttat attataacta agaaaaacaa gggggataaa ataatgaaaa 98940
tagttattgc gatcgattcg ttaaaaggaa gtttatcttc aattgaagct ggagaagcaa 99000
tcaaagcagg aatagagcat gtatatgatg atgcaaaagt aatagtaagc ccactagctg 99060
atggtggaga aggaacggtt gaggcattaa ccgagggtat ggatggaaat atgcgttctc 99120
ttgaagttac ggggccatta ggcactagag tagtttgtca atatggaatt attacagaaa 99180
cgaagacggc agttattgaa atggcgagtg ctgcaggaat tactttggta gctccagatc 99240
agagaaatcc cttactgaca acaacttacg gtgttggtga aattattgct gatgcaatta 99300
caatgggatg tcggcatttt attataggga ttggcggtag tgccacaaat gatggaggaa 99360
taggaatgtt acaggcacta ggttaccgtt ttttagataa atatggaaat caagtaacat 99420
atggagcaca aggactggaa caattagttg aaatcgatga cagtggggtt gtttcttcgt 99480
tgaacgagtg tacttttaaa attgcttgtg atgttaataa tccgctatgt ggtaaactag 99540
ggagtagtgc tgtttatgga ccgcaaaaag gggcgactgc tgaaatgata aaaaaaatgg 99600
ataaggggct taatgattat gctaaattag cgaaattaaa atatcctaac gctgatccgg 99660
aactacccgg tactggagct gccggtggtc taggctttgc atttttgaca tttttaaatg 99720
cacaattaga atcaggtatt aaaattgttt tagaagaaac acgattagaa gaatatataa 99780
aggatactga tattgttatt actggtgaag ggcgtcttga ttttcaaaca gccatgggta 99840
aagctccaat aggggttgct aaattagcga agaagtatca taagccagta attgcttttg 99900
ctggaagtgt gacagcggat gctaatgaat gtaatcacca aggtatcgat gcttattttc 99960
cgattgttcg tggtgttaca actttagagg aagcaatgga gagcagtaat gctaaaaata 100020
atttaatagc tactgttgaa caggtgtttc gtttgtggaa gataaaataa gatgatatga 100080
taaatgtata taaaatttgt tcaaaaagga gcgatgggaa tgggaatctg gattaaacag 100140
tagcatgcag ggctttactg tttatagcct tgctcgataa aaaattcagg aggcagaata 100200
tgatatattt taaatacaag aaaaaaatgt ttattgtcag atgttagggg aagagtaacc 100260
gctattgttt ttgcatggaa atacagcatc agctggagtg tttgaataaa ttttatcact 100320
atatcaagat gagtataaac ttattttaat tgatttttta ggacatggta aattacagtg 100380
aatagcgagg tttcctactg acttatggtg acaagaagct gatcagctaa tcgctttatt 100440
agaatcctta aatattaaag atgttacttt aatcgaaaca agtggaggtg tttggggtgc 100500
agttaatgct gcattaagac gctcagattt aatcacttgt gtagtggcag atagttttga 100560
tgggcgaact cttcgtcggg gatttgccaa agcattaatc gaggagtggg tcatggcaat 100620
aaacaatctt gcagcaagac aattttatca atggtgtcaa agtgataatt gggagacttt 100680
ggtgaatcaa gatactgagg cactgttaag acgaattgat ttgggtttac cgtagaagta 100740
cctttaaata ctttaaaggt actattgttg ttaattacta gtgggaagga tgcgatgtta 100800
cacagtgata tcatagaaga atatgaaaaa attatatacg agcatccacc tgttaaaatg 100860
attatctttc caacgggtaa gcatccttcg ttattatcaa atgccgtggc agcatccact 100920
gctataaaag aatttttgag cagtagtaaa caaaggagtt aactcctttg ttttagactt 100980
cagttaataa aaatagtatt tatattataa ttacaaatga tatactcata ttaattagta 101040
aaaggagaaa cagaaatgat aaaagcgata ttttttgata ttgatggaac actagtgagt 101100
tttaaaaatc atcaaatacc tgcctcaact atcgagtcgt taaaaaagct aaaagaaaag 101160
ggaatcaaaa tttttgttgc tacaggacgg ggaaaggatg gtttagatat tttagatgag 101220
attgagtttg atggctatat aaccttaaat ggtcagtatt gttatgttga taatcaaata 101280
atatatgaaa atacaattaa acgagatgat ttacagaaac ttttgaatta tttagaagac 101340
catccttttc catgtgggtt cacggaagaa cataataaat attttaatct tcgtgatgct 101400
cgagttgatg aaattcatcg cattactttg aatgatgatc atccagctgg tgattgtagt 101460
gatgtagtta ataaaaaaat ttatcaatgt atgtgcttta ttgatgagcg ggaagaacaa 101520
aaattaatgc agattatgcc taattgtatt tctgcgcgat ggcatccact tttttgtgat 101580
gtttctccca aaggaggaac aaaacaaaat ggaattgata agtttttaga tttttaccat 101640
attgatcgta atgaaacaat ggcttttggt gatggtggga atgacattga gatgttacaa 101700
catgtggcat tatcagtggc aatggaaaat ggtaatgata aagttaaaga aattgctgat 101760
tatgtgactg ctgatgtaga cgaagatgga attttaaaag cactgcagta tttcagtatt 101820
ctttaaaata agatgatgac ttatcattaa tgatgaaagt gatatttcaa gggagtataa 101880
tattgtttgt aagaggtgat taaaatggat gaaattaaag tgccttcaac tagatatcat 101940
aaaatagtaa atcttctttg tataataata ttgacaggaa cactagtctt tttggtaact 102000
aattggacga tgatcccgga tcaaattcca ggacattatg atagtgctgg agtaatcaat 102060
cgatggacaa gtaagtcagg gctatggata gtttattttg ttggaatcat aatgtttgcg 102120
ggattatcag taatagaaca ttttcctaaa acgtggaata ctggtgtagc tattactaag 102180
gaaaatcaaa aacatgttta tcaattaata aaaggaatga tagtaaccct gaaattatgt 102240
atcaccacaa tatttatgtt tttaacactg tatacgactt tgatgattaa tttgccaaaa 102300
tggtttacac cgctttttct aattattaca tttggttcaa tgatagttta tggtataatg 102360
atttatagag ctcgatgaaa ttacctaata attaagggtg tattaatctc ttattaaaaa 102420
tacgaaaatg atatttgttt ttaataataa attgaactat cgcttttaat agtgttcttc 102480
tgtaaaaaaa ttatttccgt gtctaataca ttttttttgt acaaaaataa tatattgata 102540
gcattccttt atattttatg tcttttctgt agacgatagt ttacagaaat atatcctttt 102600
attataaata atggttgacc taaagttcac tttaggtagt acaatgtatt ttgaggtggt 102660
aaaagtgaaa tatcgggaat taggaagaac aggtttaaaa gttagtgaaa taggtttagg 102720
ctgtgaagga tttatgaaaa tggatactga tcaagttaag aaatttgttg ctcaggcttc 102780
aaaaatggga ataaatttta tagatttttt ttcatcaaac ccacatgggc ggagtgcttt 102840
tggtaaagcg atagctggta aacgtgaaaa gtggattatt gaagggcata tatgtacttt 102900
ttggaaaaat gaacagtatt tgagaactcg taaaatggat gaagtaaaag ctgggtttga 102960
agatttgctg gcaagactgc agactgacta tattgatatt ggaatgatcc attacattga 103020
tgctaaaaaa gattttgaag aagtttttaa tggtgaagta attgagtatg taaagggttt 103080
aaaaaaacgt ggaattatta aacatattgg aattagttct cataatccac ttattgcaat 103140
tgaagctgtt aagacaggat tagttgatgt aatactgttt tcaattaatc cttgttatga 103200
tatgttgcct ccatctgaaa atgttgatga tttgtgggat gatgaaaggt atgcggaacc 103260
gctttttaat attgatccag tccgtcaaga attgtatgaa ttgtgccaaa ctaaaggagt 103320
tgcattaact gtgatgaaag catttggagg gggagattta ttagatgaaa agttatcgcc 103380
gtttaaggtt aaaatgacac cgttacagtg tattcattat tgtttaacgc gaccgggagt 103440
agcttcgatc atggcaggaa gtcatagtat taaagagatg atggaggcat tagcttatga 103500
agatgcaagt atggtagaaa aagattttgc taatgtttta gctaatatac caaaacattc 103560
atttgaagga aattgtgtat attgcggaca ttgtgctcca tgtgtcaaag gcattaatat 103620
agctgatgta aataaatttg cagatttatg tgttgctcaa ggggaagtac cagaaacagt 103680
tagagaacat tatgaagttt tagctcatca tgcaagtgaa tgtattgaat gtggggtatg 103740
tataaaaaat tgcccattca atgttaagat tattgaaaaa atgaaagcag cagtagcaat 103800
ttttggttat taaagctatt gcgtgaggaa acattatggt tgaaaagttt gatatagtaa 103860
tcacacaact tggattagag cgaacaatcc atgtatattt accagaagat tattatgata 103920
gtgatgaaca atatccagtg atgtatatgt ttgatggaca taatttattt tatgaccatg 103980
atgctactta tggaaaatcg tggggactaa aggaatttct tgatacctat gataaaaagt 104040
tgattattgt aggaattgaa tgtaatcatg aaggacaaaa acgcttaagt gaatattgtc 104100
cctatcaaat agaaagtaaa tattttggtc atctcaatgg acaaggaaag atattgatgg 104160
attgggttgt taacgaatta aagattctcg tcgatcaaaa gtatcgcact tatctgtttc 104220
gtgaatgcac aggcattgct ggaagttcaa tggggggatt aatggcgttt tatactgtta 104280
tttattacaa taagtatttt tcaaaagcag cttgtatatc gccatcgatt tcaatgtgta 104340
tggaagaatt gaaaaatgaa tatactcaag ctaaaatcat ggaagatacg cgggtatact 104400
ttagttttgg aactgatgag gtcaaaggga aaaatgggat tcaatggatg ttgaataata 104460
tcttatattt taatgataga ctgattgaaa gtaatgcatc tagttatata aatgttgtgg 104520
aaaaaggtca gcataatgaa gcatcctggc agttagaaaa tcaaatatat ctagattatt 104580
tatggaaata aaatattttt ttagtgattg cgattgcaga taaaatatat taaattaagg 104640
ttatagctaa gcatggttga aaccatgctt ttatttttga ttttacctaa tatggcttgt 104700
gtgatacaat tattaaagat accaacaaac caaacagaaa taatcattta tagggataaa 104760
aaaatgaaac gaaaaaagag aaaatttgcg ataaatgtaa tgtcgttagc tgtaataccg 104820
atactgattt taggaatgtt tgtaatcttt ataacctcaa gtttaattta tactgcctta 104880
aagggcgaag ttgctaataa tcttgaagat ttggctagag tatcatatca agactttgac 104940
atgcaatatc caggtgatta ttacttaaat aataaccatt tatataaggg aacagaagat 105000
attcaaaatg attttaattt ggtggattta attaaaaata ataccggggt cgatgcaact 105060
ttgttttatc aagataaacg catactaaca acaattcgtc aagaagatgg caaaagagtt 105120
gttgatacga ttgcaccaga tgaagttatc gaaacagttt taaataatga taaagaattt 105180
ttttcagatt ctgttgtaat taatgatagt agttattttg gtttttacat gcccgtaaaa 105240
aatactgatc agcacgtcgt tggaatgctt tttatggggc gtccacgtgc tgatgttatg 105300
aatcatatta tgcataatat ttatcttgtt tctctttcaa tcgttacaat tatgataatt 105360
gcaattattg tatcttatta ttatagtaaa aaaacgattt ttgctttaaa tacaacaaaa 105420
cattttttag gagcagtagc aaatggagat ttgacgactg aaatagatcc atatgtatta 105480
cagcgtcatg atgaaattgg tgatatgggg cgttttgcgg ttatgatgaa agagtctctt 105540
agtgatttag ttggaaaaga tccgttaacg ggattacata atcgccatag ttgtgatgtg 105600
gttttagcga gtttaattca gcgtgtaaaa caaaagaaca cttcttttgc agtggcaatg 105660
ggagatgttg atttttttaa atatgttaat gatacatatg gtcatcaagc aggtgatgaa 105720
actttacgtc aacttgctaa agttatttcg acccatatgg aacacctggg atttgtattt 105780
agatggggtg gtgaagaatt tgtcttgatc tatgaagata tggatcggta tcaggctttt 105840
aagcatttag aaatcttaca agaacagatt tatcaagaga gtatttattg gaaagatgac 105900
aaagttaaga ttacaatgac atttggctta gcggattcta atgaatacaa tgatcttgat 105960
gaattgatca atttaattga tgataatctt tatcgaggga aaaaagaagg tcgtaaccga 106020
attgttttta atactttaaa atagaaatta aaacatgacc gttaagataa ttttaacggt 106080
tttttagata aagatttcta attgagaaaa tatctttaat gtttcaaaag attagataca 106140
atagaactat aaactttatt aaaggtatga ggtatgaaaa atgataaaat taattgtatc 106200
agatatggat ggaacactat tggcgcatga ttcatcaatt tcaaagggaa atattgaagc 106260
aattaggtat gctcaaagta aaggagtgca atttgcaatt gctaccgggc gtgattattc 106320
aagccttaag gggatattag aggcacatga tttaaaatgt tttagcattt taggaaatgg 106380
agcacaattt tgtaatgaaa atggagaaat tttatcaagt gcatattttc ctaaaaaatg 106440
ttttaaacaa gttttacaaa tatttgatga actaaagatt cattatatga tttttactgc 106500
gaatggtttt tattcaacag ctgagccaaa tgttgttcgt gatgctttta ttgatcgctg 106560
tgttgttcag ttcaagcgca aacgagagga ctacttagat gatggctgta atcaagatat 106620
ggcgtgtatg aagttaaaaa aaataggtga cttagatgat tttattaatt cttcaattga 106680
tattattaag gttgaagcat ttaataatga tgtatcatta attgaaaaag ctaaagaaaa 106740
acttcaggaa attgatggga tagcttattt atcatcattt gatgataata ttgaagttac 106800
cgataaggca gctcaaaaag gattgatttt ggaaaatgtt attgaagaat taggttattc 106860
aaaagatgaa gtaatggttt taggtgacgg tctcaatgat attacattat ttgagcggtt 106920
taagtattct tttgcgccag gtaatgctaa tgagacaatt aaagcaatgg cttatcaggt 106980
agttggagca tgtgaagaag acggtgtttc ccaagcaatc tatatgatgt tataataaag 107040
aggattgata agatcttctt tttttgatgg gaggaattta atgatagaaa ttaaattttt 107100
aaaaagtacg gatgaatatt gggatacaat gattgactat gttcaaaatt gttcttggcg 107160
tgctggtaaa tctttggcta ataaaatgaa gacagggtat tttactaaat ggcagtgtgt 107220
agttggggtt tggtatgata ataaaattgt tggtttttcg acttttgttg aaagtgatag 107280
tatagataat agtggctatc agccttttat tggctatatc tatgtgaatc cgaattaccg 107340
tggtcaacgt ttaagtgaag tgatgattaa agaaattatt gtatgtgcaa gaaaaatggg 107400
ttttaaaaaa atatatatac atagtagtga atttggttta tatgaaaaat ttggatttaa 107460
aataattgat tgtggaaaaa cgtgttcggg aagatatgaa aatatttatg aaaggaagat 107520
tgcttaatga ttttgtattt tagcgggact ggaaatagcc gatatattgc agaggtaatt 107580
aattcagtga ttgaagataa attagtttct atcaatgaat gtttaaaaaa taatttaatt 107640
gtttcattag agcagcagta tattattgtt tgccctacat atgcgtggcg tattcctcgg 107700
gtagtggagc aatttattcg gactaatcat tttgtttcgg gaactaaaat ttattttata 107760
atgacatgtg gtggagatat tggaaatgct gctaaatata ttaaccgttt atgtaatgaa 107820
aaaaatatga ttttaatggg agtcggagag attgttatgc cagaaaattt tattactatg 107880
tttaaggcac cagaaaatcc agaagtgatt atttcacatg gtgtagaaac tgcactttta 107940
ctagcagctg aaatcaaagc aggaaaatat tttttagaaa ctaaacctac gtttatagga 108000
cgatttaata gtggcatagt caataggctt ttttatccaa tgtttgttag ggctaaagga 108060
tttcatgttg aagatacttg tattggttgt ggtcaatgta tccatgcttg tccattaaag 108120
aacattagtc tagttgattc tagacctatt tgggatgaac attgtacaca gtgtatggca 108180
tgtatcagta tttgtccaaa agctgcaatt gagtataaaa ataagacaaa gggaaaaaga 108240
cgctactatc ttaaagatag ttataataag gaaattaaat gaaaattgta attactccag 108300
ctaaacggat gaacgataat attgattata tagacgtaga aagtttacct gtttttttgc 108360
cacaaacgga ggaactgcta ggaattctta agacactaaa agtcgatgaa gtaaaaaaga 108420
tgttaggttg caatgatcaa attgctcaaa ttgcatactt gaattatcag atgatggatc 108480
taaaaaagga cacagttcca gcactgctag cttatgaagg aattcaatat actaatacgg 108540
cagctcatgt tttaactgat gatgattatg aatatacaaa acaacattta cgcatcttat 108600
ctggatttta tggtatttta agaccgttcg atggtgttgt gccatatcgt ttagaattaa 108660
ataataaagt aaagacagaa aaatttaaaa gtttatatga gttttggaac agtcgaattt 108720
atgatgaatt gacaaaagat gataatcaaa tactagatct tggggcaaaa caatatacta 108780
aaatcataaa aaaatattta acatctagca taaaatatgt taaatgccac tttaaagagg 108840
agagtgatga agggtatagg gaaataggtg tttatgtaaa gatggcaaga ggacaaatgg 108900
ttcgttattt aattgaaaat cgaattgatt catttgaggc agtaaaacaa tttaattatt 108960
taggttatca atattgtgaa gcattatcag atgtggaaac atatgtattt atacggaaaa 109020
aggggacatg atatgaaaac attaattaaa aatggaattg tgattcttga tggaattaaa 109080
cggcttaata acggtgcggt gatgattgaa ggtggaaaga ttacaggtat ttataaagat 109140
tatgaaggat tagaagctga tagtgttatt gatgttcaaa ataattatat tattcctggt 109200
cttttggata cccatacaca tggggcgatg ggatatgatt ttaataagta ttcatcaaag 109260
caggagttag aaataatcag tgatagctta ttagatgagg gagttactgg ttttaacgct 109320
agtattgttt gtgaaagcca tcacgacaca ttgaatcttt tacaaatgta tgaaggaaat 109380
accccagata atttaattgg tgttcatctt gaaggaccgt atttaaatat taagaataaa 109440
ggtgtaatga aagaagaaca tttacgttta gtaaattttg atgaatttaa tcagtatatt 109500
tcaacttgca gaaaagtgaa tgcaatgaca attgcccccg agctgcctaa tgctttagaa 109560
ttaatcaatt atgcaagtaa ccatggctat gtgatgaatg tggggcattc aagtgcaagt 109620
gctaaagagg taaaaaaggc acaagcatac ggtgcaaaag gaattactca tctttataac 109680
gcaatgtcac agcatttgca ccgtgatcct ggagttgtaa ctggtgcaat tttatcagat 109740
ttaatgtgtg agcttatcgt ggatggcttt catattgata aagatgttat tcgtgcgaca 109800
tacaaagcaa ttggaaaaga gcgaattatt ttgattactg atgctaatcc ctgtaaggga 109860
ttgccagatg ggcaatatca tttttctggt aaagatattg taattgtcgg gggacatgct 109920
acagtcaaag aaactggtag aattgcagga agcacattag ggttaaatga agcttgtgct 109980
aatatgatgc gttattgtga ctgttcaatc gatgatgccg tactaatggc ggcagttaat 110040
ccagctaaat tatatggatt aaagcagggg aagatagaaa ttggttatca gggtgatatt 110100
gttgtcatag ataaagagtt tacaatctta gcagttatca atcggggaat tataaaaaga 110160
aataagttta tttaaatatt tagtgattta acttgacttt aagaagatat ttgatagaat 110220
attattcgcg gcaacgtcta ggatatacga gtactcgacg tatagcttgg agttagctaa 110280
gttaaacaac aggaggataa ttagaatgtt aactaaagca gaaaaaacag ctattatgca 110340
aaaatatgct actaaagaag gagatacagg atctccagaa gtacaaatcg cagtattaac 110400
agcagatatc aacaaattaa atggacattt caaacaacat ccaaaagata atcattcaaa 110460
tagaggatta ttaaaaaaaa gttggtagaa gaagagattt attaaaatat ttaaaaaata 110520
aagatattga aagatattct tctttatgtg aaagtttagg tttaagaaaa taattggacg 110580
ctttggcgtc ttttttcttt acaaaaaagc tgaattgaat tcaactcagc ttttaagaga 110640
gggttcaccc ttattttgaa taagcttttt taatgataat catgtagata accaagaaat 110700
aaccaacaaa gagttgctga taaagaataa acataaaaaa cgccatagtc aaacattccg 110760
ccaataaatt cactaacaac aattaatgta aaaatcatta tctttagata attggaactt 110820
tgctgtttta ctttaaataa ttttagaata gatttaaatg aagcaataaa aaatattata 110880
aatagactcg ctccagcgat tccagttgtt acaagagttt ccaaaaagac attatgacta 110940
tgaacaacct ggatttgttt gacaacatta ctgttggtca ggtgcctacc aatagtttga 111000
aaattaccgg caccaattcc taaaataggg ttggtttgcc aaatttcaat tgaagtatta 111060
aataattcaa tacgtccact gctgatctga ttaatttgat ttaaacttgg ctgaaaatct 111120
ccttgaaaaa acaattcaat tgattcaatt actttattaa tttgaaaacg gctgcttgtt 111180
tcgtgatgat taccacttaa atatgataga ccgttagcgg tgatgatact agtaatgaaa 111240
ataatgatag aaagacctaa agaaaataga tatttcttta actttgaata ataacaatct 111300
ttaaaaaaat aagtatatat taaaccagtc aaaatgacag ccaaaataac tagagctgct 111360
cggcattgag tcaaaataat atataatagt tggacaatga tatttagttt atataatcgt 111420
ggatgtgtat attcgttttt taatgcataa agtgctaata aaatagtaat tgcactcaaa 111480
aaggctgcag gattacaatt aaaatataca ccaaataatc gatttcctac taatccgatt 111540
ggccatccat tttgaatttt cgagaattta aataaataca ttattaaaga acagattcca 111600
gctagaccgg ttaataggtt ggtcagagga ataatacttt ttaattcatc gtagatattg 111660
tttgatgaaa aacttttttg attcccgtag atcaaaaaaa agatcattag ctgtaaaagt 111720
gcaattaaat atgattttaa attactatat ggattgatcg ctgttgcaag gaacaaaatc 111780
aggccatagg taataattaa aataaattta atatcatggt aattaatttg tttttgataa 111840
aagtcccatc caatgataag tcctccccat ccaatcatga taaataacaa aatattaaga 111900
ttgaaaccta ggtaacctag ggcaagtgta ttgataaaag cataaataat aaatgctaat 111960
ttaaaatatt ttcttgataa tagataagtc tgcataatcc ccctccatga tattcattct 112020
aacaaaatat tgatattaat actactttaa tttgtttgct gcgatttgct tattacaata 112080
actattaaaa tagttaaaga tagtgtataa ttaatgaaga atatttagaa atgagggact 112140
ttatgaagaa tattacattg gttattatgg cggccggaat tggtagtcgt tttggaggtg 112200
gcattaaaca attggcacca gtaggaccaa atggtgaaat aatcatggat tattccattt 112260
atgatgctaa aaaggcaggt tttaataaag tagttttcgt tattcgtaag gatttagaag 112320
cagaatttga tgctgtgatt ggatcacgaa tcaaacaaat tattgatgtt gaatatgttt 112380
ttcaagaact agataatatt cctgacgaat accaagaaac atttaaacaa agaacaaaac 112440
catggggaac agggcaggca attttatgtt gcaaggatgt aattaatgaa ccatttttag 112500
ttattaatgc tgatgactat tatggtaaac aggcatacga agaagcttat aaatacttaa 112560
atgaaaatca tgataatacg gctaaacaac agattgcgat ggttagtttt gtacttaaaa 112620
atactttgag tgataatggt ggtgtaacac gtggggtgtg cacggttgat caaaacaatc 112680
atctttgtga tattgttgag acacataata ttgaaaaagg tgataattgt gcatttgtta 112740
aaaaagaaaa tcaaattatt gaacttgatc tcgaggtacc ggtatcaatg aatatgtggg 112800
ctctacaacc agaaatattt gatattttag attctaagtt caaattgttt ttatctcaat 112860
tagagaatga taattttaaa gatgagtatc tattaccaac tattataggt tcactattaa 112920
aagaaaatca ggttgaagtg actgtgttaa aatcgttaga taattggttt ggagttacat 112980
ataaagaaga taaacaaaca gttattgaaa gtattcaaaa attaacagct gtcggtgttt 113040
atccacaaaa attattttaa tagaaaccga aggaagatgt gggtatcttc cttttgtctt 113100
tcatcagcat atactctttg gtataattaa taatgatatg aaaaacgggg aaagtcgaat 113160
ggaacaaatt aaattaattg aaaaattatt agaaataagg aaatataagg aaattaaaga 113220
aatcttaaaa gaaatgaacg atgtggatgt tgccgaaatg ctcgaaggtt tttctgatga 113280
aaatatgata cgtatattta gattattgcc aaaagatgat gctgcagata tttttgcata 113340
tatgtcaagc gacagagaac atgcgttaat agattcgtta accaataaag agttagagaa 113400
tattattaat gatctttatt cagatgacgt aatggaactt cttgaagagt tacccgctaa 113460
tgttgtgaag cgaattattg ctgcttccaa tcctgagact cgtcgtgata taaatcattt 113520
attacgctat cctgaagatt ctgcaggtag taatatgaat atcgattttg ttgatttacg 113580
tgcagatatg acagttaagg aagcgattgc acgaattaga cgtattggag tagataaaga 113640
aacaatcaat acttgttatg taatcgataa ttttcgtcat cttttgggaa ttgttacttt 113700
gagaaagtta gttttatcat cacaaagtgc tttgattgag gagattatga acgataatct 113760
tattacagtt catacgatgg aggatcaaga ggatgtagca catgattttc aaaaatatga 113820
cttaacttca atgcctgtgg ttgataatga aaatcgttta gttggaatca ttacagttga 113880
tgatattgtt gatatcatgc aggaagaaac aactgaagat atcgaaaaaa tggccgcaat 113940
ggtaccgtca gacaagcctt atattaaaaa tggcccgttt gaaacattta aaaaaagaat 114000
accgtggctt ttgttattaa tgatttcagc ttctattact ggaaaaatca ttcaaggatt 114060
tgagcatgct ttagcgggct ctgtgatttt aacggctttt attccaatgt taatggatac 114120
tggtggtaat tcaggttcgc aagcctctgt ctcaattatt cgggctttgt cactagatga 114180
aatcaaacat agtgatatcg tcaaaattgt ttttaaagaa tttagagttg caattttagt 114240
tggggttact ttagcagcat gtaattttat taaaatgatg attattgatc atgtttcaat 114300
catgatagct gctgtagttt gtctaacttt gatagttact gtaatcattg ctaaaatcgt 114360
tggctgcact ttaccaattt tagctgataa attaggcttt gatcccgctg tgatggctag 114420
cccgtttatc actacgatcg ttgatgcttt gtcattgttg atctatttta cgattgctac 114480
taatttatta aatttataaa gtctctggaa gattccagag actagttttt atttacaaga 114540
atcattattg cgtagatctt gtaatgcttc aatagcacaa caggcttttt cttttaatgc 114600
gttttctagt tcctttacag taccaattgt ctgtgctgct gattcattga ttgcaattaa 114660
ttcatcgata catttagcta aacatactgc ttttttaatt ttttcacttt cagcacataa 114720
aattgcagct aaggcacctt cttgcattgc aactgattgt aaaacagccg ctaaggcaca 114780
acgttcatca acgcaacaac cttcaataca gcaattgtcc atgcagcagt catcgataca 114840
aaaatctcga ttacatgaat tcatgggttt catctccttc catactataa gatatgcaag 114900
gggaatagat tgttagtggc ttatgtcttg aaaaacaaaa agagcgtgat aacaacgctc 114960
ttatatattt attcaactgt tactgattta gctaaattac gaggtttatc aacatcgcaa 115020
cctttaagtt tagcggcata ataactgatt aactgcagtg ggattgcaac taatactgct 115080
tgtaaaattg gatttacatc gggcatgtaa taagtttcat caacatttcc aacctcttca 115140
ccggttaatg taaataaaat gacttttgct cctcgagcaa ttgtttcttg aatattgcta 115200
attgtttttg aagctatatg tggttgtgta gcaactgcaa ttactacact gccttcttca 115260
atcaaagcaa ttggaccatg ctttaattca ccagcaatat aagcatcagc atggatatat 115320
gatacttctt ttagttttaa agcaccctct aggacggaag cataatctaa acttcgccca 115380
atatagtagg catctttttg attttttaaa tagttcgcat atttttcaaa tagtggttca 115440
tcttttaaaa tattttcgat ttgtttaggc aatttagcaa ttccgttaat aatgtcttta 115500
tagatatcat tttcttttcc tagggtctgt gcaacataca ttgctaataa taataagaca 115560
ataacttgcg tagtataggc tttagtactt gctacagcaa tttctggtcc tgcacaagta 115620
taaattgttg cttcagcttc acgcgagata gttgaaccaa gaacattagc tacggcaatc 115680
gtagtacaac ctttattttt tgctaaacgt aaagcagcca tggtatctgc agtttcaccc 115740
gattgtgaga caaaaataca cagagttttt tcatcaatga tagggtcacc atatctaaat 115800
tctgaagcgg cttgggtaaa agtaggaata ccagttaagc gttccataat attggctcct 115860
gaaaggcaag catgatatgc agttccgcaa gcgacaaaat atactttatt aaaagttgta 115920
aaacgttctt tcaatatttc tagttcaggc aaaataattc gatcattacc ttcaactcgg 115980
cctcttaaag tttcactaat agcatatggc tgttcgtgaa tttcttttaa catgaaagta 116040
tcgtaaccgc ctttttgagc tgcttcatta tcataaggga tatgtgtaat ttctttttga 116100
atttcgttgc cttcagcgtc atagaaagtt attttatttt tacataattt agcaatttca 116160
aaatcatcaa taaaatagac atctttggtg tagtctaata aagcaggaat atcacttgcc 116220
ccaaaacttg cacagtcact tgtccctaat actaatggac tgtctttttt agttacataa 116280
actacatccg gctctaaagt agaaacaatg cataaagcgt aacttccatc aatgtgagta 116340
atgacctttt ttaatgcttt cagcatatca ccatcatagt aagaatctag tagatggacg 116400
acaacttcac tatctgtttc gctatggaat ttatacccct tagctactag ttgttccttt 116460
aattctcgat aattttcaat gattccatta tgcactagtg aaatagtgtt tttattattg 116520
gtatggggat gagaattaag gttagatggg actccatgag ttgcccagcg agtgtgacca 116580
attccgacac agccaattgg agtatcttga tctagtcgat ctatgagatt ttgcaatctt 116640
cctttcgttt taatcgtgaa aagtttatct ttatctacaa gggttacacc agctgaatca 116700
tagccacgat actctaattt agaaagtcct tgaagtaaga atggtaaagc ttcttcttta 116760
ccggaaaacg cagtaattcc acacataaaa attcctccat agttttgatt attcaattgt 116820
tattatgtta tcaatggagg ataccgaatg aatttgttta atgattaccc attatttttg 116880
ttcattgttt aggtagtatc atacctctag accatccgcc gaatatttcg ataagtctag 116940
ccctcgtcaa ctaattactt agtcctggcg ctattttgta tttctgtctc cttaataaca 117000
gttgctatta tatacaaata aaattaaaaa agcaacccat attataatat gaagtatttg 117060
ataatagatg caaagaaata aagcataaat aattagtttt attatttaca ttgactcatt 117120
tcctgataat ttttaattat tttatgaata aattaaaaaa aattgtaaaa aataaaagtg 117180
attttccaag tttaggagta aatgataata ggagggataa attatgagtg tacatgaaaa 117240
tttaattgaa ataagtaaat cattagagaa tttagaagaa acaggtattt atgacgttga 117300
aaaatacagc tgttcattga aacatttgac aaatcaacta gaatattttt attgtcattt 117360
agttaaagaa aatggacgtg atattgacag tacatattat catctttcta atcgaccaca 117420
agttcatcaa ttagcatatt tcaatatcgg acgtggtttc cctaaagaat taatggatgg 117480
gcactggtgt tatattttaa aggatcttgg ctataaaatg ctgattattc catgtacttc 117540
tataaaagga acaagtgcta atccagaatt tgaaatggat attgaagtga tgatgtcggg 117600
cgtaaagact aaaagtcgtt tacagttgag tgagatacgt tgcgttgata tgcagcggct 117660
tgatttaaga aagacatttt gtgatgtttt gagcagtcat gatgatatta taaagtatgt 117720
aaaagagcat ttgttaaaat aaaaatagcc taacaagtag gctaataaac taaaatgagt 117780
agagttatca aaagtaatat acaacaaaat aacagcgcac attgtccaaa aatattaatt 117840
aaacctgtag caataatggc tccaatgata aaaaagaaga taataatcaa atagcgaaaa 117900
caatgatgta acgcatcttt atcatgagcg aataaatatg ctgatagttt ttgaccggca 117960
gatctcaaat tcccagtaca cattgtcgag gcatacggta aaccattagt tgttctaaat 118020
gtatttactt gtaaagaaca aactagacca attgttacgt tgcaaacact atagggaatc 118080
tctttaggga tgaatgcaat gatcgtcaga ataataattt caataattaa gattaaatgt 118140
tgccattcaa catattggac attacttaaa cgatgcttaa tgtattcact aataacaata 118200
cctaaaaaga aagctgatat tggtaataaa taatataaag cacctaaata gttttgctca 118260
gcgattttaa gtcccataag aaccatgttt ccagtttggg cattagcaaa aacattgcct 118320
tttagaagat aggtataaat atctaaaaag cccccaacga tagcaagcaa gattcctgtt 118380
aaaagtgatt catgaatcgt tgcttttaaa aaatttttaa ttttcatcac gttaaaacat 118440
gtagcaggaa tgctacatgt ttattttata agtttagtag acgttttgta tcgcgagcaa 118500
ttactaattc ttcattagtt gggataacga atacttttac ttttgaatta ggagtactaa 118560
ttaaacgatc tccttgacca ttaacatttg catcttcatc aagttcgata cctaaagcat 118620
cttttaataa atcacaaatt ccttttcttg caaagaatga attttcacca attcctgcag 118680
taaagcaaat tgcatcaaca ccacctaatg caataaaata acgaccaata taagcaataa 118740
cacgacgata gaaaatatcg attgcaagtt gagctctttc attaccttct aaagcagcat 118800
tttgaacatc tctaaaatca cttgacacac cagaaatacc aagtagtcca gattctttat 118860
ttaacatcgt aataacttct ttcatgtcca ttccaacttc ttcaatcaaa taatcgatta 118920
cagaaggatc gacgtcacca ctacgagttc ccatcataat tcctgcaagt ggagtgaatc 118980
ccattgaagt atttactgat ttaccgtctt taacagctgt taaagatcca ccagctccta 119040
aatgagccac aataactttg gaatgttcag gatttccaag catttcgatt gctcgttgag 119100
aaacatagaa atgactagtt ccgtgagcac catatttacg tactttatag tctgtataat 119160
atttatatgg aattggataa atatagcatt taggatctaa agtttggtga aaagcagtat 119220
caaatacagc tacagctcca gcttcaggga ttgcttcctt aaatgcataa tatccagtta 119280
aatgagcggg attatgtaat ggtgctaatg attttaattc gtcaatttta ctaacaacat 119340
cttcatcaat gattgctgaa gaatcaaagt atgatccccc ttgaacgaca cgatgcccaa 119400
cacctttgat ttcatttaac tcttttacaa ttcctttttc aattaaagta tctaataaaa 119460
gttgtactgc aactttatga tctttaattg ggttagttgt aacagtcttt tttccttgat 119520
atttaatcgt aaagattgaa tcttctaatc caattctttc gattactcca gatgtaatta 119580
cagattcgtc atccatttca aataattgaa actttaatga agaactacct gcatttacag 119640
aaataatttt tgccatttta taaagcctcc ttaatctatc gtcattatat catcattttg 119700
taaaatttct agataaaagc attacgttta ttaattttaa tatagatttt tttaatcatt 119760
ggataaaaag aatacaaatt attattaata ggtagatttt taactttaaa gttagataaa 119820
atataaaaat attttttata aatgttgtat tgtcgaaata ttgaacgagt ttaggcaata 119880
ctgcacttgt agaagaaata atttattata aaggagaaga ttatggaaaa caaagtgtat 119940
ggttatgcaa gagtttcaac aagagaacaa aatgaggatc ggcaaatgat tgccttggag 120000
aattatccaa tgtcaaggaa acaaatttat cttgataaat taagcgggaa agattttaat 120060
cggccgcaat atcaaaaatt attaaggaaa attcgtgctg gagatacaat cgttattaaa 120120
tcaatcgatc ggttgggacg tgattatgaa gaaatacaaa accaatggcg taaaatcact 120180
aaagaaaaaa atgtaaatat tgttgttttg gatatgccat tattagatac acggagtact 120240
ggtgataatt taacgggaac attcgtggca gacttggttc tacagattct ttcttacgtt 120300
gctcaaacag agcgtgaaaa tattcgtcag cgtcaaagag aagggattga agcagcacga 120360
atgcgtggtg tgagatttgg acgccctcgc aaagaaattc ccgaaaattt tgaaattttg 120420
aagcatcaat ggcaacaaaa tttaattgct tcacggcagg ctgctaaaga attaggcgtt 120480
tcacaggata cttttttaag atgggctcat ggaaaataac attagtacat ttatttgtcc 120540
ttaaaaggta gacaatatcg ttcaaatgta ttaaaataat atatatgttt ttatagtgtg 120600
aaatttgtta ttttataata ttttattacg aattttgacc gcataataga tgcttgataa 120660
tctctgattt atcgttctct atatgcaata aaagcatatg aatttcggta tatgcgttta 120720
gggagagaaa cgcatatatt ttattttaga aaaggagaaa agcgatgggt ctacttgaaa 120780
aaatagccga tattatgcag tgtacctata tttctgattt aagaggaaga ttatcgcttg 120840
accatgaaca gttacagttt ttaaatgaat taagagctga aacatacgct ttgtctgaat 120900
ggcaagaagc agtaaggtat attactggta atttagattc ttttaattcg gcagcagaag 120960
gaaaaaacat cttattggat tactatatta aaaaagaagc tacagaaata tcaataaaat 121020
gatttttttc ttgatattat aataagataa tctataatag tatacgagcc aggggtgcaa 121080
aattgctgag aagggcataa gcctgatccc ttatcatctg aactgggtaa tgccagcgta 121140
gagagagcaa atttaaaatt gtttgctttt ttgcgttcgc aaagaagcat tttttaattt 121200
tgttaggctc tttcataagg aaggggaaaa acaaatatga aaaacaaaac atttaagatt 121260
acaaccaaaa caattgctta tatggcgatg tttatggctt tacaagtagt tttagaatta 121320
gcttttaaag tcgttccggg acagcctcag ggaggaagta ttacgctgtc attagtaccg 121380
atcctattag cctcatattt attaggtgga tattacggta ttgttgttgg agcctgctgc 121440
tgtggactgc attttgtttt agggttggct acatattggg ggccatggtc attattttta 121500
gattatttaa ttccactagc tgtaattggt atagcatcat tttttaaaaa ctttgagatt 121560
aaaggtcatg tagtttatcc tggaattatt gttgtaatga ttcttaagtt tatctcacat 121620
tatttatctg gagcatggct gtttggagca tatgctcctg agggaatgaa tccatggtgg 121680
tattcatttg gttataattt agcctattgc ctaccaactt taattatttg ctacatcgga 121740
tttgccttaa tatatccacg attaaataat tcgattaaac tgtaaaagaa aagtagcttg 121800
ctacttttct tttcttctgt ctttaaaaag gatagtaatt tgtgtataat agtactgtta 121860
taaagagagg tagtaaaaga tgtcagattc tctggtagga aaaaaagtat taattcactg 121920
ttataagcac gatggaagta ttcatcgatg ctgggccaaa ggattcatct tagatgaaaa 121980
tgatgatcat tttattgcaa tcaataatcg caccttagta actgaatctg atggtcgaat 122040
gtggcataca agagagcctg ccatctgtta ttttcctaaa aataagtggt acaatgtgat 122100
ttgtatgatt cgtaaaacag gagtttatta ttattgtaat attgcttcac caactttata 122160
tgatggtgag gcattgaaat atattgatta tgatttagat ttaaaagtat tcccagataa 122220
taactatcgg gttttagatg aagaagagta taagcaacat gctaaacaga tgaattattc 122280
aaaagaattg gatagaatat taaaaaaaca attagaactg ctaattgatt tagcaacgaa 122340
acgtgaagga ccgtttagtg aagattttac gaaacattgg tatcatgtat atgaagattt 122400
gacacaagga taggagaata caatggaaaa agtaattaaa gtaaataacc ttgaagaaac 122460
gattgctttg ggtaatcgtt taggcttgtt attacaacca aatatgctat tgactttaag 122520
tggcgactta ggagccggga agacgacctt taccaaagga attggtcaag gattagggat 122580
taccaaggtt attaatagtc ctacttttac cattttaaaa caatatcaag gtcgcttgaa 122640
tttgtcacat tttgatgctt atcgtttaga aggacaggat gatgatttag gatttgaaga 122700
aatttttgat agtgatgatg tttgtgttgt tgaatgggct aattttattg aagatatttt 122760
accggtagac cgtttaacaa ttgaaataaa aaaaattgat gaaaatattc gcgaatttgt 122820
ctttaaaaca aatagtgaaa aatacgctca agttgtggag gctttaacat gaagacaatt 122880
gtaatggata catcaaatgc ttatttagtt attggcttat acgaagatga tcaatgtatt 122940
gataagtatc aagcagatgg aaatcggcgg caatctgagt acgctttaac acatcttgat 123000
gaaatgttga aaaaacatca ttgggaagtt ttaaatgtgg atgaaatgat aattacgatt 123060
ggtcctggtt cttatactgg tcaacgggtc gctttgacga ttgccaaaac tttggcagca 123120
atttcaaaaa taaaaatcaa ggcagtttct tcgttacatg gttatgctgg agcttctaag 123180
gcaatcagtg taattgatgc tcgaagcaaa aagatttttg ttggggtata tgagcataat 123240
caggccataa ttgatgatca aatcatgttg attgatgatt ttgctaattt taaagaacaa 123300
tatcctgatt ttcaagtgat tggtgatagt gatttagtcg gaattaacaa agttaaactc 123360
gatttaagtg attgtattta tcaagctggt aaaagtgttg attattgtca aaatattgat 123420
aatcttgttc ctcattattt aaaagatgtt gaggcgaaaa aaatatgtta atcagacgga 123480
tggatttagg tgatattgaa gaagttgtaa agttagagca tgatttattt agttcgccat 123540
ggaatgaaga agcttttaaa tatgaattag aaaaaaatgc tttttcatca attttgattt 123600
tggaagataa taatataatt gttggttata taggaatgtg gacactagga gaccaaactc 123660
aaataacaac tatcggtgtt agaaaagagt tccaaggaaa aggctatgct aaaatattaa 123720
tgactaaatg tgatgaaatt acaaagcatt taggctattc gaatattaat ttagaagtcc 123780
gagtttctaa tactaaagca attagtttat atcaaaaatg tggctttaaa attgccgcaa 123840
caagaaaaaa ttactatcag gataatcatg aagatgcgta tttgatggta aaagaaatgg 123900
aggaataacg gtgtcactta ttttagcaat tgaatcaagt tgtgatgaga tggctatggc 123960
aatcttaaaa gatgaacgag aatttcttag tagtgtcgtg gcctcacaga ttgatgttca 124020
tgcgatgtat ggtggagtag tgccagaaat tgcaagtagg aaacatgttg aatgtgtttc 124080
gctagtatta aaagaaactt tgaataaggc taacgttacg attgatgaaa ttgatgctat 124140
tgcggtaact aaaggaccgg ggttagttgg gtctttgcat atcggtttac aggccgctaa 124200
aacgattgca atggcttatc ataagccatt gattggagta catcatattg ctggacatat 124260
ttatgccaat aactatgttc aaaatattat ctatccaagt ctttgtttag ttgttagtgg 124320
tggtcatagt gaacttgtct tattaaaagc tccttttaaa tttgaagtaa ttgggcaaac 124380
ccttgatgat gctgttggag aagcatatga taaagtggga cgagttttaa atttaccata 124440
tcccggggga cctataatcg ataaaatggc tgctaaaggt aatcatactt ataatttacc 124500
agtgcctttg gatgatgaaa gctataattt tagttttagt ggattaaaat ctgctgtaat 124560
taatttaaat cataaagcga tgcagcgaaa tgaagaaatc aatcaagaag atttagctgc 124620
ctcttttcaa gatgtggttt tatcggtttt agtcaataaa acaatacgtg ctactaaaga 124680
atatggtatt aaacaagtat taatggcagg aggcgtgagt gctaatcgtg gattgcgaaa 124740
tgcgatgggt gaagcggttg gccaattaga tggagtagaa ttattattac cgccaatgag 124800
ttgttgtact gataacgcaa tgatgattgc tttagcagca aaacagatgt acgatttgaa 124860
attatttagt gatttgtcat tagggattaa gccaaattta gatttagaaa atgaatcggt 124920
tagcggggga aatcaaaatg gataaaaaaa tatcaaacgc tacaatgtct cgttatcctg 124980
tttatcttaa agctttaaga aaaatgcagc atgaaggtaa agaaaattgt ttatcaagcg 125040
aattatctag tttaacaggt attcaagata cgacgattcg tagagatttt acttatttat 125100
caaagacaga taattttggc caacgtggta aaggttatga tgtaaaacat ttaattgacg 125160
gattaagtga ggtattagga ttaggactag acgaatcaat tattttgatt ggtatcggaa 125220
atcttggtag tgcaatttta aaatataacc gttggcaata tacagtggga aaaattgtct 125280
gcggctatga tcaagataaa aataaagagg gagagcgttt tggtgttaaa ctctataata 125340
ttgatgattt agaaaaaact tttcctaaag actgtaaaat tgcaatcttg gctatttctg 125400
aaaacgttca accaacagtt gatcgtttaa tggatttagg aattaaaggt atcgttgatt 125460
ttacacatac acattttaca gttcgtgaag gagtcgaggt acaacaggta gatgttgttg 125520
tagcaattca agaattagtt attaagatgg attcaaatcg tcaataatac ttgaataatg 125580
gataaaataa agtatataat aggaaaaact aggaggatta atatgtttga atttataacg 125640
gttagagaac tatatgaaat gtttttaagt aaccaaatga tggatttaga aggttacgaa 125700
tatgttgaac ttgagggatg ggttcgaact aatcgtaaca atgggaaatt gggatttatt 125760
gctctaaatg atggtacata cttcaaaaat ttacaagttg tatatacaga agcagaaatt 125820
tctaactatg aagaaatcga taaattatct actggtagtt caattcgagt agttggaaaa 125880
ttaaagttga cacctgaagg aaaacaacca tttgaagttg aagcaactga gattgaaatc 125940
gaaggtaaat gtgatgaaga ttttccatta caaaagaaac gtcattcatt cgaatatatg 126000
cgtgaaatac cgcatttaag acctcgtgcg aacactttct atgcaatttt tagattgcgc 126060
agtgttttat caatggctat tcatgaattt ttccaatcac aagggtttgt ttatgttcat 126120
acaccaatta tcactggaaa cgatggtgaa ggggccggag aaatgtttag agcaacaact 126180
attgatggaa ctaattttga agatgatttc tttgaaaaag aggctttctt aacagttact 126240
ggtcaattac atgttgaagc ttttgcaatg gcttttagag atgtttatac atttggtcct 126300
gcatttagag cagaaaactc taatacttct cgccatgcta gtgaattttg gatgattgaa 126360
cctgaaattg cttttgctga tttagaggat gatatggatt taattgaaga tatggttaaa 126420
tattgtatcg attacgtttt agataatgct cctgcggaaa tggaattctt tgcttcaatg 126480
attgataaag attgcatcaa tcgaattact aaagttaaaa acagtgattt caaacggatg 126540
acatacactg aagcaattga aattttagaa aaagcagatg ttaaatttaa aaataaagtt 126600
tcatggggaa tggatttaaa tagtgaacat gagcgctata tttgtgaaca ggttgttaaa 126660
ggaccagttt tcttgacaga ctatccaaaa gaaatcaagg ctttctatat gcgtttaaat 126720
gatgataata aaacagtggc tgcttgtgat ttattggttc caggaattgg agaattagtt 126780
ggaggaagtc aacgtgaaga aagatatgat gttcttgaaa gaatcatgga tgaaaaagga 126840
atgtctaaag atggtttaca atggtatatg gacttacgtc gctatggtgg ctgtaaacat 126900
gcgggattcg gtttaggatt tgatcgtttc ttaatgtatt taactggaat gcaaaatatt 126960
cgtgatgttg aacctttccc aagaacacca agaaatttaa aattttaaca aaaaggccta 127020
tattttatat aggcttttgc tttgaatggg ttataataat agataaggag gcgatcaaat 127080
aatgaatgag tatgatttaa taaatgctta tctaaattta atttttgatg atagcataac 127140
ttattttagt cgcattcttg acgaatatcg tggtttatgc cagttgagaa aatggatgcg 127200
taaacgtggt attaatttaa aagccattga aaatattggt tatgatatgt ttttagcttt 127260
tagtaaagct aaaaatgctg aacaaatcat ggaaaaaatg gatccgactc atttagaaga 127320
attaaaagag tatattaata cagaacgtaa taaatatcag atcgtagtat tatcaagttt 127380
tgattatagt gagccaatta atgcgtattt aacctcaaat cagattgtgg atgatttaga 127440
cagtgataat attagggttt taaattgtca taatctatta aaaaaagaag atttatcatt 127500
ttatggacct tttaaacatt ttgttacggc cttatatcaa attgatcgct ggcctggatt 127560
tttaattttt aaaggtgatg agtgtgcatt tgttcctatt tatactactc aggacattga 127620
agaagtcatt tttaaaattg aacatgatac aattttttca attcgatatt taagtcctta 127680
tgatagcttt tttgtgcagc taagtgattt acaccttggt agcaaaaaga agaatatcgg 127740
tcgtttggca cttgaagata gtcttgatca aactgttaaa cagctacgtt cttattatcc 127800
tttaaagttt ttgattacgg gggatttaat gaattcacca aatcgaaaaa atatgtatga 127860
ggcatcaggg tttatgaaag ggttaaaaaa tcgttataat gcagatgttt cctttatttt 127920
aggaaatcat gatgtaattg ttaatggttt taatattttt aagcgtcaga aaagtaaagt 127980
aatcgccttt ttgttaaatg aaagcattaa agtatttgaa gaagaaaaga ttgttttaat 128040
taagattgat tcaactgtag aaggtaattt agcgcgtggt aaagttggaa tgaaacaatt 128100
aaacaatatt gatgaagagc ttgccgctat taaaaattta ggagattata caattgttgc 128160
aatgctgcat catcatctgt ttccaattac ccgtgatgat tttttaaagc aaaaatggcg 128220
tgaaaagatt tttgttggga aaattatgga tagttctaag gcattagtag acagccgtga 128280
tttagtagaa tggttaagaa aacaccaaat tcagtatgtt ttgcatggtc ataaacattt 128340
accatttttt agcagtcaag aagggatgta tgtgattgct gctggttctt catgtggcag 128400
tggagcaaaa gaatcaaaga gtcgatattt aagttataat gtattaaaat atgaccatcg 128460
ttataaacga tttaaatact gttttatcat ttatgatgat atgacgatgc aagaccgtca 128520
aagaatagtt ataaatattt tttaggagag aaaaatgaag ttagtagatg gaatgaaaga 128580
tgaaaaatta gggagtgctt tattgtattg ctttactaaa ggttatggag ctgtaccgat 128640
ggatctttat aatcttgttt taccattatt atttgatgat atttttagag aagaggtaaa 128700
gataagcaaa gattttagta gttgtattag ggcttgtatt caaaaaaatt ctgaatttgt 128760
taatcaaatt ctaaatagtg ttgaagaatt agaagaggta acgagtcgca gtttaggaat 128820
ttctttatta aataaagatc ttgattttca aatcaatgat ggtgtaatga gcggaaattg 128880
tcgaccatca aaaattcttg atttaaatga agctattatt ttaggaaaaa tgatacaagg 128940
aaaaggtttt gatgaagtag ttacaatgat gaaaagtgat tttaagattg tctttttgga 129000
tagtgagaca ctgggtagtg atattgatgt cagcaaatta aatcgatatg gtgatgtaac 129060
aatatatcat caaagtcaag ttagtgaggt tcctgagcgg attaaagatg cgagtgttgt 129120
aattactaat aagcatatat tgaaagagga acagttaaaa gatgctcata aattaaaact 129180
tatttgtgtt actgcgacag gtgttaataa tattgatctt gaatattgta aggctgccgg 129240
tataaccgta tgcaatgtta aaggctattc aacaaatgca gtagcacaac atacattcgc 129300
tttattatta gatttataca ataaaaatca ttattaccat aattatgttg agagcggtaa 129360
ttatgcatca agctctatgt ttacccattt aggatacact ttccacgaat tgactggtaa 129420
aacttgggga atcgttggaa tgggcgatat tggccgtaaa gttgctgaaa ttgcaaccgc 129480
atttggctgt caggttcaat attattctac aagtggaaaa aataaccagc aaaattatca 129540
acaggttgat tttgatacat tactggaatc aagtgacatt attagtattc atgcaccttt 129600
aaatagtcaa acagaaaatc tttttgacca atcagttttc gcaaaaatga aggattcagc 129660
atatttaatt aatgttggaa gaggaaaaat tgtaaatgaa gcagatttag ttgaggcatt 129720
aaaagaacat cgcttagcag gagctggctt agatgttttt gaaaatgaac cattctgttg 129780
caacagtccc ttattagaaa tcaaagatgc aacaaaatta ataatgacac cacatattgc 129840
ctgggcacca attgaaactc gtaatcgtgt gattgaagag gtttgtttaa atattgaagg 129900
atttaaaaca aataatttac gaaacgtttg taatatgtta taatttagtt ctagtcgtgg 129960
tgaaagattc gcttctttta tcatatattg gagatagctt tgctatttcc atttttttga 130020
tttattgatt ttaaaacctt tttataggat ttaaactgca taataaaaat gcataaagtc 130080
ttttctttgt ttataatata agtgtaaata aaggaggaac taaaaatgaa atatgctgta 130140
gtagatggaa aattaacaca tgtaaataag gttcctaaag gaacaattgc aagagaattt 130200
ggttattcta attatcctgt aattgcctgc aaaggaaaat atcgctcata ttggaaatat 130260
gtaagtgtta ataaagcaaa ctatgcctaa ttcaaactct catctttcga tgagagtttg 130320
ttttgattta aaaacaattt attgcatttc atgtttaact aagctagaat tattaagaaa 130380
tattaataga agggtttaat ttcatgaaag aaagagaaaa attttcatca agattaggtt 130440
ttatcttgat atcagcaggg tgcgcgattg gacttggaaa tgtatggcgt tttccatatg 130500
ttgttggtca atatggtggg gcactatttg tattaattta tttatttttt ttaattgctt 130560
taggagcacc aattatgaca atggaatttg cagtcggacg tgcaagccaa aaaagtgcgg 130620
cattagcatt tcattcgctg gtacctaaga gaaaattttg gggtgcaatt ggaaaatttc 130680
aaatggctgg aaattatatg ttgatgatgt tttatacaac cgtcggaggc tggatgattg 130740
cttatttttt taaaatgata aaaggtgact ttaacggtat tactccagca caagttggag 130800
atatatttaa taattcgctc caagatccat ttatgcaagt attctggatg attgtagtgg 130860
ttgttttggg atttggaatt tgttccttgg gccttcaaaa tggtgtagaa aagattacta 130920
agatcatgat gagttcatta ttaattatta ttttgatttt ggtgatacgt gctgttactt 130980
tacctggtgg tagagacggt ttggcgtttt acttaattcc taatttagcg gcaattaaac 131040
aatatggtct tttagagatt atttttgctg caatgggaca agcatttttc actttaagtt 131100
taggaattgg ggcaattgct atttttggaa gctatattgg caaagaacgg cgtttatttg 131160
gtgagacaat aagtgtatgt actttagata cgttagtggc attattatca ggcttaatta 131220
tttttcccgc atgttttgct tttggagtaa atcctgaaag tggaccgggt ctggtattta 131280
ttacgttgcc tagcattttt aatgaaatgt ggttaggaca agtatgggga tgcttatttt 131340
ttgtctttat gagtttcgca gctttatcaa ctataattgc agtatttgaa aatattattt 131400
catttgggat ggatttattt aattggagtc gtaaaaaagc agttgtagtt aattttatta 131460
ttattttaat tttatcttta ccttgtgccc ttggctttaa tattcttagt gatattactc 131520
catttggtat cggaacaaca attcaagatc ttgaagattt cttggttaca tataatttcc 131580
tgccacttgg ttcattagcg tatttgttat tttgcacatg tcgttatggc tggggatttg 131640
atggttttct ccaagaagct aatacaggaa caggaattaa attcccaaaa tggacaaaaa 131700
attatttaaa atttattctt ccttgtgtga ttatttttat atttattcaa ggatattata 131760
cgtttttcat taaataattg tttgataaaa ggtgttgctt taagtaacac cttttatgca 131820
agttatttgt tgaattttga taatatttga ttgttctaac cgataaagag taaatatgca 131880
atagttgcaa gaaggcaagc aatcgcatca agccaaagac ctaattttaa ggcgtatcga 131940
ttattttgaa gttttatact gccaaaatac aaggttacaa cataaaatgt agtatcgctg 132000
cctgtctgaa taatggagcc aagaatgcta taaggatgat caaccccata ctttaaaaag 132060
atattattta aaatagttag tgatccattt gaagaaaatg gtctaacaat catcatcata 132120
aagatatcaa taggaatatt caaaatagca aaaatactct taaaaccgat ttctagtagt 132180
tcaattaggc cgcaatactg aaaacatgtg acccatagtg taaaagccat cattgttgga 132240
aataaagtaa ttaggagttt actgccttcc tttacccctt cgataaattc attaaaaata 132300
tcaacgtgtt taaaacttgc ttcgactaga gctattaaaa tgataattaa gattacacta 132360
tccataatgt tcaatcacct tacttgcaat aataccgacg attgtaatga cgaaaccaat 132420
agtaagacta tagccaaaga agccaaggat gtcgtggctg ccataacttt gtcttaacgt 132480
catcattgtt gtaggaatga ttgaaaggcc agtagtgttt aaaataacta aaagcatcat 132540
ttctttgcat ggagtctttg gatcacgttg gtattttgtc agagattgca ttgcttttaa 132600
accactaata gaagccaaag aaccaactcc taataaatta gcaataaaat tagttgagag 132660
atatagataa acttgatcat cttcgaccgt attaccatag ataagtttta aaatcggctt 132720
aagtaaaaac gataattgtt taataagtcc cgaagcttta ataatattta aaaatccatt 132780
ccaaagacaa gcacttaaaa cgattacttt gattaagtca aaaacttgtt gtggtgaact 132840
taaaattgct tcaaacattt tattttgatt attagtgcaa aaagcaatta tcacaaagaa 132900
aattaaacca aatttaaaaa ctttagccat agaataaatc cttcaggacc attttgaaac 132960
ctaaaaagta attgtatgga acaacttttt gtttagcaat tggctggtta tttaataaaa 133020
ttacaatttc attattattt aatgaaactt caactttatc agttggtttt ttattaacat 133080
agacatcaaa gtctaaatag tactgttgtt gtttaaattc aacgatacct tttgagaata 133140
ttttagttgc ttttaaatta gcataacatt cttcaaattt cttttgatga aattcaaaat 133200
catttccaca attaaaagta acaataatta aatcaagatc atctttacga gccatggtaa 133260
ttagggttcg tcgtgctttt ttggtaaaac cagtttttcc accaatacaa tattcatagt 133320
tggttaataa tttatttttg ttatgccaag tcccattacc gtcttcgcgt ttgtattctt 133380
tagtactgac aatttcatta aaaattggat tttgatggca ataggccatt aatcgtgcca 133440
tatcataaac agtggattga ttcccgttat cttcttcatc taaacctgtt ggattagaaa 133500
aagttgtgct atgcaactga agttcttttg ctttgtcatt catcatatca acaaattttg 133560
gaatttcttt accaactgct ttagcaatca ttacagcagc atcgttgcca cttctaagca 133620
tcaaaccata tagtaagtca cgtagactga ttttatcacc tatatgtata tagacaccac 133680
ttccccaggc tttatttatt gtatcatcaa ctgtaatgat agtatcaagt tccatgtttt 133740
caatcgcaat aatacaggtc ataatttttg aaattgaagc aacgctctga atgtaatctt 133800
gattactgcc ttcgattacg atttgatgac tagcttccat gacaatataa ctttttcctt 133860
ggaagggtac agcactgacg tttgtattta ctagtgtcat cattaaactt ataattaatc 133920
ctaatttcat tttcttcacc cctttaaaca tatgttgaac ttggaaaaat agaagtttta 133980
gagtagaaaa taaaactgtc aaaatatcct aatatttgta attataatat taattgtatt 134040
aaatccaggt aagatatata actataagca ttgaatttgt ttcaataacc caaaatttaa 134100
tattagtctt tgtggcatga ggagaatccc taccgatggt tacagttcat gacccatatt 134160
ttataatatg gctgagttag taaaattcta atatcgacgg ttaaagttca gatgagaaaa 134220
gacattttct agaattctat cgaaggcatt ttattatgtt ttcggttttt tattttagga 134280
ggaagaaagt tgaaaagagg aaagacaagg taattagtgt tgaacgcaat tttaggggca 134340
ttataggcga tgctgatggt attttgattc ccattacctt taataccacc atttttatat 134400
tttgatacag cttatgttta caggtgaatt acaaagtttt atggttaagt attgctttgg 134460
tttaaccagc agccttgatc tatcgttatg ataaaactaa aattgttact tttaaaggaa 134520
cgtgggttga aattattatt aatgtaggag ttgttctctt taatttaatt aaaagtatta 134580
ttgtatattt gattacatta ttggtatata aaaaactaag tactataatt catcatcata 134640
caggtgacta aaagaaaaga gaggtgattt ttgaagatgg agctgtttta ttttttaaaa 134700
aattaggaaa ttggaaaatt atgtattagc gactagtgta gatgattatg taacggttcg 134760
taatattagt tgtttatttt aaaacagata aaaattttag aaaaactcaa caattattta 134820
aaaatcctca agttgcatta tgcaatggaa gaattcaaat agaagggctg acgaaaaata 134880
taggcttagt gattgaaaaa ctgggacgta aatttgagca gttatatcgt cagtatttat 134940
gacaaaatta caatgcgtat agttatgaaa aacagagatt ttaattgagg ctacacctaa 135000
gttcgttgaa atttgggatg aaaatgaaaa tcattttact tttcaaactt ttattgattt 135060
tgaataaaaa cagttacaat aaaaaatgtg attaaaggct aaaaaaacaa ataatccctt 135120
gtcgttcgac aagggattat atcattaaat tttagacttt atttatattc ttcaattagt 135180
cgttccaaat aatctttata tttagaatca ttggcattaa gtttatcaga actattggta 135240
tattttttta ctgcggttgt agctctagtg attggtaata aagttccagc tccagcaaca 135300
caaccaccgg gacaagccat accttcaagt agataaccgt catatttacc actttttgct 135360
aatttaagca tttttttaca atttgctaat ccttctgctg attccactaa tacttcacgt 135420
tcaggctctt tagctttaat acaatttacg actgctttag caaccccacc gctaacggca 135480
aaaccgcgac catcactact agcctgagta aatggatcag cttcatctgg ttttaaagaa 135540
gcaaaatcaa tgcctttagc ttcaaacatt gcgccaattt cttcaaatgt taaaacaaaa 135600
tcaacctcac ttcgtactga ttttctagaa gcttctagtt tttttgctgc acatggccct 135660
acaaaaacaa ctcggctatt aggatgtttt tcttttatca aacgagcggt taataccatt 135720
ggtgttaaag ccattgatat ataagattta aattccggga attctttttt ggccatcatt 135780
gaccaagaag gacaacatga tgttgccata aacggttgct gagcaggtac tttttctaaa 135840
aagtcctttg cttcatcaat tgtacataaa tcagccccaa tggcaacctc aaccacatcc 135900
ttaaaaccta attgctgcat tgcttttttt aaaacttctg gtgtgacttt aggaccaaat 135960
tgtccaataa atgcaggagc tactgctgca ataatttcat cgccggcctt aattgcttga 136020
attaattgga aaatttgact tttatcagca atggccccaa agggacagct aactaagcac 136080
attccacaag agacgcattt atcataatta atgtgggcat taccatattc atcagtttca 136140
atagcatcca ttccacaagc cttagcacat ggtctttctc tttttaaaat tgcatcatat 136200
ggacaattag ttttacaaag accacattta atacatttat cttgatcaat atatgctttc 136260
ccgtctttaa agctgattgc atttttagga caaacttcga tacatgggtg cgctaaacag 136320
gcctggcagc cactactgac ctcaaatttc ttttctggac atttattaca ggcaaattta 136380
ataatgttga ttaatggtgg ttcgtaatat ttgtcggcaa taatactttc ttcaatccct 136440
ttagatattg gtgctggttc atcaataggg cgcaatgata atcccatcgt taaacgaatt 136500
ctttcaccga caatagcccg ttccaaaaaa atactgtcac gataagttgc gacttctcca 136560
ggaattactt tatagggtaa attttcgata cgactataat cattcccctc ataggctaac 136620
tttgcaactt caacaaaaac tttacgtcga attttagtta atgatgaata aattcctctc 136680
atagtgtttc ctccatatta tttataacta tattttactc caaagtgcaa gtttataaaa 136740
gtgaactgta ggatatttat ataaaaataa gttattcgta agataattgg ttgcttttaa 136800
ttgacaattc agtataatga ttacgaagta ggtgaaaaga catggaaaga ttacaaaaag 136860
caattgcggc aagtggttat acttcgcgaa gaaaagcgga agacttgatc gttcaaggaa 136920
aagttgaagt aaatggcaaa gtcgttactg aattaggaac caaagtaaaa cagggagatt 136980
taattacagt tgaaggaaag ccgttggttg gtgaaaataa agtatattat gttttttata 137040
aacctaaagg gtgtgtttgt actttagatg atgaatttga ccgacctatt attacagatt 137100
attttactga agttaaagaa agaatttatc cagttggaag actagatttt gatacaacgg 137160
gattaattat tatgtctaat gatggagaat ttgctaatat gattatgcat cctcgttcac 137220
atttagaaaa aatttatgaa gtatctatta aaggtttaat tactggacca actttaaata 137280
aactggaaaa gggtgtttat ttagaagggg ttaaaacttt accatgtaag attaaagtcg 137340
ttgacaaaga taccgaacat aaaaccacaa tgctgaaaat aaagttagta gaaggtaaaa 137400
accgacaagt taagaaaatg tttgagagtg taggacatcc ggttaaaaga ttgcatcgtg 137460
taagtattgg tggaattaat ttaaaagggc taacaccagg aagatatcgt attttaaaac 137520
cgcaagaagt aaaagatcta aaaaaattag ttaatacgga taagtagatc acttatccgt 137580
atttattttg acaattattt taatttgttt ggtgcatact gtattttggg tgatgaaaat 137640
gagaatacaa atagttgaac cacaaaataa aattgaatgt ggaatatgca aagccgaggg 137700
tgattggatc aaacgaataa atgtacgggg gattcaagct ttatattgta tcaagtgtga 137760
cacagtgaca atgtttaata agatgccatc aaagtttgtt tataaggcat taaaaaaaga 137820
aaccgaaaat attcggatgg cttataattt aaaacaagac gaaaaagtta aataaacaaa 137880
ttagttgact ttaatcaata aatgagtaga attagtatag taaatagatg cgatgattta 137940
ggatatgtct agataatact ttgattcaga gaaaagacgg gtggtgcaag tcttgataag 138000
gttatttagg tactccctaa tatgcaacac tcgaaagaga atgtcggtag tgcgttatag 138060
ctttgaggtt atttcgataa caaattaagg tggtaccacg atactctcgt cctttggatg 138120
agagtttttt tattaaaaaa cagtaaagga gaaaaataat gattgatttt aaagaagacg 138180
aaaaactaag tgtattaaat cactcttgtg ctcatgtaat ggcacaagca attaaacatc 138240
tttatcctca agctaaattt tgggttggtc cagttgttag tgaaggattc tattatgatg 138300
ttgatttagg aaatgatgta atcaaagatg aggatattcc taaaatcgaa aaagaaatga 138360
aaaagatttg taaagatggc aaacgtatta ctcgccaaga aatttctaaa gaagaagcct 138420
tagaaatgtt caaagatgat gaatataaaa tagatttgat caataatttt gaaaatgata 138480
caactattag ttgttatcgt caaggagatt ttgttgattt atgtagaggt ccgcatgttg 138540
aaacagttaa agcttgtaag aactttaaat tgactaaaca ttcaggtgcg tattggaagg 138600
gtgacaaaga aaataaggta ctacaaagaa tttatggtgt ttgttttgaa acttctgaag 138660
acttagctaa acatcttgaa ttattggaag aggcaaaacg gcgggatcat aagaagctag 138720
gtaaagaact aggattattt atgatgagtg aatacgctcc tgggatgcca tttttcttac 138780
cgaaaggaat gattttaaga aatactttag aacaattctg gtacgaagaa catgctaaag 138840
aaggatatga attcattaaa acaccaatta tgatgtcacg tgaattatgg gaaactagtg 138900
gtcattggga aaattataaa gaagatatgt atactagtat ggttgatgac cgtgaatttg 138960
caattaagcc tatgaactgt ccaggaagtt tgttagtata taaaaattcc ttacattcat 139020
acaaagattt accattaaga atgggtgaac taggtcaagt tcatcgccat gaagctagtg 139080
gagccttgaa tggtttattt agagtacgta cttttactca agatgatgca catatctata 139140
tgacacctga tcaaattgaa ggtgaaatta taaggttgat taatttcatt gatcgtgttt 139200
atggaagctt aaatttaagt tatgaaattg aattatctac ccgtcccgag aagaaatata 139260
ttggtgattt agcaatctgg gaaaaaagtg aagctgcttt agctgccgct tgtaaagcag 139320
caggtaagga ttataaagta aatcctggag atggtgcttt ctatggacca aaactcgatt 139380
tccatgttaa agattcatta gggagagttt ggcaatgcgg aacaattcaa ttagacatga 139440
atttaccaga gagattcgat attacttata ttgatgataa aggtgaaaaa gttcgtccag 139500
ttatgctgca tcgtgttatc tttggatcga ttgaaagatt tattggaatt ttaattgagc 139560
attttgctgg tgtgttccca ttatggttgg cacctgttca agttaaagta ttgccggtta 139620
ataatgagta tcatttagac tatgctaaag aagtaactga gttattaaag gataaaggct 139680
ttaaagttga actagatgct cgtgaagaaa aattgggtta tcgaattcgt gagggacaaa 139740
tggaaaaggt accttattta ttagtattag gtaataatga acgtgatgaa aaaactgtta 139800
catatcgtaa acatggagag caaaaacaaa ttactgttcc atttgatgat tttgtcgcaa 139860
tgctaaatca gcagattgtt gataaaaaat agtaaacact tagcaaatta aatttgctaa 139920
gtgttctttt tggtttgata aacttctatt ttatagatgc gtaattaaaa ttattagaat 139980
aaatttacat tatttatatt tcgaagaaag atatagatgt gatataatta aaatattgaa 140040
aagagggata aaaagatgaa atattattta gcaatggatg ttggtggaac gtcaataaaa 140100
tatggtgttg tcaatgatca gggaaaaatc attaatactg ataaaatcgt aacgcccgat 140160
tcactagaaa aaatgtatca ggcaatgggt gagatttatc ataattgtaa ttatgaagta 140220
acgggaattg cattaagcat gccaggtgcc gttaacagtg aagttgggaa tattgaagga 140280
gcaagtgctt tagattatat ccatgggccg aatatcaaag aggatctaca aaaacgcttc 140340
aacacaaaag tttcaattga aaacgacgct aactgtgcag cattagcaga agtttggaaa 140400
ggatctggaa gtgatgtgga tgactgtatg ttcattgtta gtggcactgg gataggtggt 140460
gctgttgtta aggatcgaat gattcataaa ggaaaacatc ttcatggcgg tgaatttggc 140520
tatatggtgg ccttaaatga tcttgataat gattcctata tttcttggtc tactgcagga 140580
tctacagttg caacagtaaa aggggttgct aaagaattgg gagttgatta tcaaacttta 140640
gatggtaaag tgatttttga tcaagcacaa gataacccta tttatcaaaa atatgttgat 140700
cggtactata gtgtcttagc aatggggata tataatcttc aatatgtcta tgatcctgaa 140760
aaaattatta ttggtggagc aattagtgta cgacctgatt taattgaaca gattgaaagt 140820
cgtttagaaa aaatatatga tagtattcct gttgcaaaaa ttcatcctaa agtagttaaa 140880
tgtcgttttg gaaatgaagc aaatttaatt ggagcagttt atcactttat tcatagctag 140940
tcattaagaa ttcatattat tgtattaaaa tattattaaa taaaacaagg ggaggtaaaa 141000
aaatgaaaag agaagcacca aaaatcaaca cacagctaag aagccataca attatggtac 141060
cagagtgtat ccgcaatgcc agtggaatag ttattaatgg caaaagaatt aaatcattat 141120
tattctcaac agatgttgca gtaatatcca attgtaatgc tgatgctgta atcgcggttt 141180
atccatttac cccaaccatg caaattacta attcaattat cgatgtagca caacgtcctg 141240
tttttgcggg cgttggcggt ggaacaacag caggacctcg agtacgggag attgctttgg 141300
atgcagaatt acatggtgca actgcagttg ttttaaatgc acctacaaaa actgaattta 141360
ttcaagaatt atctgattat gttgatattc cagtagtatt atcaatcgtt tctttagatg 141420
aaaatcttga ggaacgcatg ttacattctg gagcgacaat tgttaatgtt tcgggtggta 141480
agaatactgt tgcaatcgtc aaagcattaa gagagatttc tcaagatttt ccaatcattg 141540
ctaccggtgg acctaatctt gaaacaattc aggcagttat tgaagcaggt gcaaatgcca 141600
ttacatatac accgccttca aatggtgaaa tttttaaagc gatgatggag gactatcgac 141660
agcgttgcca acatcaatga tttgttttgg gtagattgat atctaccttt tttgttgttc 141720
aaactggtat tttattgtac aatagttgct gaggtgtaaa aaatgaaaca atatctagat 141780
atgtgtaaat atgtattaga aaacggagaa aatcgcgagg atcgaacagg aacaggaaca 141840
cgtagtgttt ttggatatca aactcgttat gatttgagag atggtttccc gttgatgaca 141900
actaaaaaaa tgtttttgcg gccaattgct gaagaattat tgtggtttat taagggtgat 141960
acaaatatca agtatttagt tgatcgcaat gtcaaaatat ggaatgaatg gccatatgaa 142020
gattttaaga aatcacctga ttttaatggt gaaacaattg aagagtttgt agaaaaaatt 142080
aagacagatg atgaatttgc aaaaaaacat ggtgatttag ggccggtata tggcgctcaa 142140
tggcgtgatt ttaattatga aggggttgat cagttagcaa aattagttga tagtctgact 142200
aacaatcctt tttcaagaag acatattata tgtgcatgga atccagcaca agtagataat 142260
atggcgctgc cgccatgtca tgcattttta cagttttatg ttagtgcaga taaaaaatat 142320
ctgtcttgtc aactatatca acgtagtgcg gatatttttt taggggtacc gtttaatatt 142380
gcttcgtatg ctttaatgac ggaaatgtta gcgagaactt gtggatatga agcaaaagaa 142440
tttatccata cgattggtga tgctcatatt tataaagatc attttgaagt agttaaacaa 142500
caaattgcaa gagaaccatt accaaaatgt aaattagtat taaatccaga tgtgaaatca 142560
atttttgatt ataagattga agatattaag atagaagatt accaaagtca tggtaaatta 142620
gttggaaagg taagtgtata atgataaata taattgttgc aacagatgag gatctgttaa 142680
ttggaaagaa ggattcacga aatggaatgc cttggaatgt tccggaagat ttacaacatt 142740
ttaaggcaac gactttaaat aaaacaattt tgatgggatt gactacatat caggcaatcg 142800
gacgtccttt gcctaatcgt aaaactattg ttgttagttt tgaaccgttt gaagatgaac 142860
gagtagaagt gagaagctca ttagaagaag taatagaaga ataccgtagt agtggtgaag 142920
atttatttat ttcgggtgga gcttcaattt ataaacagtg tttaccaatt gcagaccagt 142980
tgttaatctc aaggattcct ggaaaacatg aaggtgaaac atattttcct aattttgatg 143040
aatacggtta caaattggtt gctcaaaaac catttgagac atttacatta gaaacatata 143100
agcgaggata attaaatgaa gagaattgca ttgattgtta ttcgtgttat ttggcggtta 143160
ccatattggt ggggatataa agtcaataag tataaacata ttgataaata ttctgctgat 143220
gaacgctatg ggtttataca tcaagttgta gcaattgtaa cacgcaaagc aagggtagag 143280
ctagagtgtt atggggtaga aaatttaccc aagaaatctg gttattttgt tgcccctaat 143340
catcaaggat tgtttgaccc gctagcaatt tttcaaaccc atagtcgtcc aattcgagca 143400
atcgtaaaaa aagaattggt atcagtcatt ttagtaaagg atgttattaa gatgctggaa 143460
tttatttcga tggatcgcag taatgttcga gaaagtgcaa aaatcattaa atatgttgct 143520
aatgaagtag cggcgggaaa aaactttttt gtttttccag aagggacaag aagtagagac 143580
ggcaataata ttttagaatt taaaggggga acttttaaaa ttgcgactaa agcaaaagca 143640
ccaattgtgc cggtagcttt gattgattgt tataaagtat ttgataataa tacgataaaa 143700
aaaacaacag ctcaaattca ttatttaaaa ccaatttatt atgaagaata taaagatctt 143760
catactaacg atattgccaa attagttcat gatcggattg aaaaatgtat taaagaaaat 143820
gacaaaggat agaaatatcc tttgttttat gttataatct atttagaaaa tattctaaat 143880
agattggagt gatgattgtg gggtttgcag aaacatttaa ggcactttca gatccggttc 143940
gtcgtgaaat attggtgtta cttaaagatg gtaaactctc agcaggagaa attgcaggat 144000
gttttgaaat gactcaagca acagtatctt atcatttatc aaaattaaaa caagcagatt 144060
tgatttttga aaataaatac aaaaattata tttattatga aattaatact tctgtttttg 144120
aagaagtaat gttatggctt agccaatttg gaggatttaa agatgaaact taaaacggca 144180
ttaattacat gcggagtatg tttgctgccg attctatttg gactaattat ttatgattgc 144240
ttaccagcac aaatgccaat tcattggaat atagcaggtg aaatagataa ttatgctagt 144300
aaagagattt ttgtttttct attaccgata ttgatgagtg gaattcaact attgtgcttg 144360
tttatgatgc aaatggatcc taaatacaag aattattcat ctaagatgtt aaaaattgtt 144420
gtttggataa ttccaacgat aacaattgtt ttagaagcaa taacatatgc aatcgtattt 144480
ggatatgaaa tctcaattaa tatagttgtt ccaatatttt taggaatatt atttgttatt 144540
ttagggaatt atttacctaa atgtcgtcaa aattttacta tgggctaccg attaccatgg 144600
actttgaatg acgaggataa ttggaataaa acaaatcgtt tagctgggta tgtaatggtc 144660
cttgggggta ttttaattat tattatgagt ttctttgatc tggctttttg ggcagtaatt 144720
ttgtttgttg gagcgatttt aataatccct tcagtgtatt catttttact ctatcgaaaa 144780
aaataataaa atagatgatt cgatacattt ttatttaaag aattaaatag aaatgtatct 144840
ttttagatgc tttgtttttt tatttgaagt acaataagag taggagatga taatatggga 144900
aaattggagg atttaccaaa tattggtaag gtagtagcac aacagctgat acaagtagga 144960
attgatgatc cgataaaact gaaagaagtt ggagcaaaag aggcatggtt aaaaatacag 145020
caaatcgatg aatctgcatg tattcatcgc ttatatgcac tagagggggc agttgaggga 145080
attaaaaaaa cgcaattaga ttatgaaacg aaagcagaat taaagcaatt ttataatgag 145140
cataagttat gaaaatatta gttaatggta ttgagttatt ttatgaaata tcgggtcagg 145200
gacggccgct tattttagtt catggtaacg gtgaggatca tcatattttt gatgcattag 145260
tggccaaatt gaaaaatcac tatacttgtt attgtgttga cagtcgtggg catggtttaa 145320
gttctagtgt agctgtatat agttatcaat caatggctga ggacataatt gagtttatta 145380
aaagcttaaa attatcggag gttgcctatt atggttttag tgatggggga atcgtcggat 145440
tattagtagc gagccaaagt aaactgataa aatatttaat gattagcggt gctaatgctg 145500
accctgatgg cttaaaaaat tgggcttatt atttgatgaa aatacagtat tatttaaaaa 145560
aagatgtaaa gattaaaatg atgctggaac aaccacatat taatgaatat caattggcta 145620
agataactgc aaagacgcta attttggtag gaagtgatga tatgatcaaa gaatctcata 145680
cgttatatct cgctcacaat ataagtggaa gtcaactaat gatcttgcct aatgaaaatc 145740
atagtagtta tattattaat agtgcaaaac ttgcgccaat tattttggca tttttaaaag 145800
tcgcttaatg aggtgaatac aattttttgg acgctaagtt agttatatta ttaataagga 145860
ttgattcttg ttaagtagac aaatgaaata aataaaaagt gtgagatgtt ttactgattt 145920
ggtgaaatgt cttttttata tcagtatata attattgtgt aaaattctta aattatcgaa 145980
atactcttga atatgtatat cttcttttat aggatactga gttggttcct tgactgtatc 146040
taaagctata aagcgtactt ctggtggtgt tatatttttg aatcgttctt gtaacttttg 146100
ttattgtaga aatttatata ggaattaatg gattctttta atccttcata aacatgaaat 146160
ttctttaaat catgcacatt gtgctttcct agcttatacc cttttgataa tgaaataagt 146220
aatattcctt gtatttgttt aatatagata ccaatttttt gctctgttgt tggctttgct 146280
ataataaaaa ccccaaaagt tggttatatc cagctttcgg ggtttgcttc acaatgtgac 146340
ttttttaaat aggtatttaa ttcttcaata tttggtaagc cttcgttatc tccaagtgtt 146400
tgaacttgaa tcgcgccaat tgcattcgca cgaatcaaca tatctttact acataatgct 146460
tccaaatgac ctgaaataat tcctgctgca aagccatctc cagcaccaac tgtatcaatc 146520
acttttttta cattaaatcc aggaactgtt aaagtttcat ttttactgct gtaataagca 146580
ccttgggaac caagctttat tacgagttca tcacagccta gctggtgata atatacagcg 146640
attttttcag gatcatcact gcccatgaga atttttcctt cgttattgcc tggtaagaac 146700
atattacaat atttggccat ttcattagtg gtatcgatca ttgttgtttg attaggccaa 146760
agagatggtc ttaagttcgg atcaaatgaa atataaagac cggcttcacg agcttttttt 146820
acaagcctta aactagtttc tcgagtttta gaagacagtg ctagggggat acctgtaata 146880
tgtaattggt caaagtcatt taaattgatt tgatcaatta gattagtgtc aatattcgaa 146940
aaagcagaac cttgacgata atagtaaata tcaggatcac cctcaataac ttgatttttc 147000
atcatcattc cagttggaaa aagactatta tagtaaacta atcttgtatc aattccttct 147060
tgataaagct tttttttaat gtaatgaccc catggatcat cacctaaaac agttaaatac 147120
gtagcttgat gccctagtct tgttaatccg atagcaacat taacctcggc tccagctagt 147180
gtctttttaa acatctcggc ttcatctaat gaatcatacg atgttgttgt aagcagagcc 147240
attggctctc caaatagtaa tatttttttc attttatccc tccagacata aatgacattt 147300
acaaccgctt attagttcat taaaatagat aaattcgatt ttatttttat ggttgtaacg 147360
agcagtttgc atatcaaaag tataaccttg tttttctaga aagaatattg cccgttcaat 147420
actcttggtt gacaaacata ggtggtggag ggaaccacta ggcgtatcaa acataaattc 147480
tatttcatct accattcttg aaatagaaag atttttttga tgaggactat tgattagagc 147540
cgctaattga gcacctcgat caccagctcc gattccaaca tgatgaaatt taatatctag 147600
catggtttta actgcttgtt tagtaatagc agtaatttca tcccatttat gttctttaat 147660
taattcatcg ctgaccatcc aagtcccgcc acaagcaata attttatcaa atgctaaata 147720
ttcagttaaa ttactagtgt ttattccgcc ggttggcatg aattttaagt tgcaatatgg 147780
cgctgacatt gccttgattg cgggaagccc accatttgct tgagctggaa agaattttac 147840
tacatctagg cctaattcaa tcgcctgctc catatcactt gggttggcac aaccaggtaa 147900
aataggaata tctttatcaa gacaatattg aacggtcttg ggattaagac cgggtgaaac 147960
aataaattca ctaccagctt caattgctga atttacttgt gctggattta aaactgtacc 148020
agcaccaata atcatttgtg gacaagcttt cttcatagct ataattgctt ctttggcaca 148080
tgcagttcgg aaagttacct cagcaactgg tagaccgcct tcgcataaag ctttggcaag 148140
atatggagca tcttctaaac actctatttt aattactgga actataccat ataatgatat 148200
atcgttgatt attttattca tgttattatc ctttcatttt tccgccattc attggtgaag 148260
tagcaagttt tgtgtagatt gataaaattc catttttata ttttggttct tttggcttcc 148320
atttagcatg gcgctccttt aatatttttg taatttcttg tgaggtacgt tgttttcctt 148380
caattccaat aatttctaat cgacgttgag gaacatcaat tttgatcaag tcattttcct 148440
cgattaaagc aattggtcct ccctcactag cttctggtga gacatgacca ataactggtc 148500
ctttgctagc tccagaaaaa cgtccatcag taattagtgc aatactcttg gctagttcct 148560
gatcagaact aatggcttca ccagtataga acatttcagg cattccacta cctttaggtc 148620
cttcgtaacg aataaatact gcatcaccgg gtttgatttg ttttttgatg atcgcgtcaa 148680
tggctgcctc ttcgctatca aatgggcggg ccctaagaac agcttgcatc atttcttgag 148740
gacatgctga atgtttgatt actgctccat ctggtgctaa attccctttt aaaatggcaa 148800
ttgttccatc ttttccaatg ggatcatcat atggtctaat aatatcagtg ctttttagat 148860
tgatcttatc caaaaatgtt tggcaatttt catagtaacc attatttttt aattcttcca 148920
aattttcacc taaagtttta ccagtaactg tcattacatc taaattaaga ttctctttaa 148980
ttgcttccat gaccgctgga acaccacccg catagtaaaa atattcagcc gggtattttc 149040
ctgcaggacg aatatcaaga agataatgtg cattttgatg catctgatca aataaatcag 149100
catttagatc aattccaaac tcacttgcaa tagctggtaa gtgtaacagt gaattagtac 149160
ttccagaaat tgctgcatga accataattg cattttcaaa tgatttcatg gtgacaatat 149220
cgcgagctgt taaatccatt ttggctaatt taattatttg ttttcctgct ttataggcct 149280
gctcttttaa atctttacaa gtagctggca ttaatgctgt accaggtaac atcaatccta 149340
atgcttcggt cataatctgc attgttgaag cagtccccat gaaactacaa gctccacagc 149400
ttggacaggc atgatgctga taatactcaa attgctcttt ggagatttca ccacgtaaat 149460
acatggcact atattttccg atttgttcta aggttagcat atctggacca gcttccatta 149520
cacctccagt tacaaagata caaggattgt taattcttcc ggctcccatt aagtgagcgg 149580
gcataccttt atcacaactt gcaacaaaaa cactgccatc aaagggagtt gcattattgt 149640
gaatttcaat cataccagca atcatatctc tagatgctag agaataattg ataccgtcat 149700
gcccttgtgc ctcaccatca caaatatcgg tagtgaaaaa ttttgaggct ttagcaccat 149760
gatcattgat ccctttttca acctcataga ctagatctaa aagaccaaca cttccggggt 149820
gggagtcacc gtaagtactt tcaatcataa tttgaggttt gcttagatcg gcaacactcc 149880
atccagtacc aatccttagt ggatcaattt caggtgcaat tttacgtaat tcttgtgatt 149940
tcattttatc ctcctatgac gtatgacgtc ttaaatataa tttaattcta aaaggcttga 150000
tgatgtttgt caatagcgtt aattaaaatt gacaaaaata ataaaatgtg taagaattta 150060
taggcgaggc gagaaaatga aaaaattagg aagtaaaaaa acgctgccag agttggcagt 150120
agagcaaatt attggctata taaacgaaaa tggtcttcaa ccaggtgatc aattacctaa 150180
tgaagttgac ttaatgaata aacttaaagt tggacgtgga acgatccgtg aagcgattaa 150240
aagtctaaat tcaaaaggag tcgtaataat taaacgtggg attggaactt ttgtggctga 150300
tcagccagga atcagtgatg atccactggg gtttactttt gaaactgata aaactaaagt 150360
tttaatggat gctttggagg tccgattgtt gatagaaccg caaatgatta ttaaaacaat 150420
tgataatatt agtgcaaaac aacttaagga attatcagac ttagctgatg aaattgaaag 150480
cttaattaac aaaaataaag attatactgt acaagatatt gaatttcata ctttattagc 150540
tcgggttagc ggtaatcggg ttattggaaa attaattcca attattgctg gagcgattga 150600
acaagctatc gatgtaactg ataaatccct tgtccaagaa acaattatta cacatcgttt 150660
gattgttgaa gctgttgcta ataaagataa agaaggagct agtaaagcga tggctagaca 150720
tatccaagat aatattgata tattaaagac aatttaaaaa aagcttagta aagatgagat 150780
atcgcctaaa gttagattcg ataactaacg atcggagatt gattgaataa actaagcatt 150840
tttatttata aggaaattac ttacaaatag ataactaatc aatgctgcaa ggaatttgaa 150900
tggggcataa taaagaatag ggataaccaa ggggaaaata tttagtagta catcgataat 150960
ttactaattt atgatagaaa aaataaccta aagtaataaa gaaagaggca cagccaggcg 151020
gcataaaccg ttgttaataa ggatatatag attaaaatta agtggtttga ataatttgct 151080
atgaataaca attactttaa ttgctatggg tcggcggatt aaattaatac ttttattttc 151140
tatggaactg attctccttt tatctattgt aggcacaaaa aagaaagcaa ttactatttg 151200
ctttctataa gacgattaat tcttttctgt ttttcactgg ttaaaagggc ctcaggatca 151260
ttaaggtatt ggattaaaag gtcagcattt tttattaatt cgctatattt atcatcaatt 151320
ctttctttat ttgaatgatt ttttattgct gttacaatag tatctatttc atttgctgaa 151380
aagagttcat ctttttttaa tagttctgag gcaattaaac tactacgatt agcgtgatca 151440
aagctagaat tcaatttata tgtagcaaga tcatgtaaaa tgccgattgt tgcagcaatt 151500
tctatattta ggttattttg gattgctaga tatttcatca ttgcagcaac gctaaatagg 151560
tgttctaaac catgtttacg cttattacca aagcaattag tgtttaaaat ttgataaact 151620
tcgtccttga ttatctcata tcttctcatc gtcttaaccc ctttggaaaa agatttttta 151680
cttgattgtt actttctttg taaaatgcta atggataacc atcgacaaga atcaaaccat 151740
aacctttttg gttattaccg attagagttt ctccgtgaag atatttggaa atatttaaat 151800
catcagcttt aaagttataa tagcgtttaa catcttcttt ttttaaagaa agagccagag 151860
aatgacttgg ttcaaaacgc ccttttttac attctcctaa atataaacca ttacgtaaga 151920
cttttgtccc ctttagatct gggaattgcg gtaaaattgc ataaatatgg ttattagaat 151980
tatataaata ttgggggact ggaaggttta agttattgtg ataaaattta gtaacaagat 152040
ttaattgatc tttagtaaca ttcggtttta agaaatttat tttttttgtt gaaccattag 152100
tatgtttttt caaaagagca ataaattgcc cctcaccttt attaagatga ggatacattc 152160
ggacaacttt atcattctga taaccagaag ccattcctgg ctgttttttt atttctaata 152220
actccatttg taaatcattg gtcatatatt taacttgatc ttcattttct tcaagcgaat 152280
aggtacaagt ggagtaaatt agaatacctt catctttaag catttgataa gcgctgttaa 152340
ttaaatttct ttgaatataa gcacactcat ttactttttc aattgaccag gtctctactg 152400
cttgatcaag tttacgaaac attccttcgc ctgagcaagg agcatcaagg atgatcttat 152460
caaaaaaatt attaaaatac ttttctagtt taactgggtc gctattagtt acaattgtat 152520
tttgaagacc aaaacgttca acattttcag ataaaatacc agctctaagt ttattgatgt 152580
cattagcaat cattaaacca gcactactta acttactagc tgtaaagcat gtctttccac 152640
caggcgcggc acacatatct aatacataat cgtcatgatc aaagtcaagg cagttagcta 152700
ctgccatagc acttggttct tgaatgtaat ataaaccaca gttaaaataa ggatgttttc 152760
ctaactgata attttcataa tcataaaaat aagcatcatt gatgtaggga tgtttggtta 152820
aaaatgctga atttaaatgt tcaatacttc catgctttag gggatttaaa taaaaacttt 152880
taataggttt ttgatttaat gcggattcaa atgcaggata gtcattctgt aaaagctttt 152940
gcattcgttg ttcaaatagt ttgttcatag ttcacctctt ttttattata caagaattat 153000
aaataaaaag acaagcatcg cttgtcttta attatttttc attaataata tgacttaatt 153060
cagccagtcg atttgctaaa cggcttaatt cttgaattgg ggcttcaaga tataaatcaa 153120
catcaatttt ctttattgct tcttcgtgtt tagcgttttc ttgtaaaccg actaatgttt 153180
ctgttgtagc gtctaatgaa gtagtaattt catttaattc gctaataatg ttttcatatt 153240
ccataatatt acttcctttg tccataattt tgttcatccc tatattttat actaaaaata 153300
cgttattttt attcattcgt caatagatat tctaaaatta ctaaaacaag tgaagaataa 153360
gtttgattaa aatttttttc tatgacgtaa aaagtgttga tatagagaca gtttttttac 153420
ttgaatttaa taaaaatatt tttttgttaa attcatttaa atttagtatt gcttttatta 153480
aaagaattct ttataattaa ttctgttagt tgccgttgta ggcacatggt tatatgtgaa 153540
atgacaattt tgccagaatg tcatatttat atatagcata aatttatttt gcccgagtga 153600
tgaaattggt agacatgaac gactcaaaat cgtttggttt ataccatgtc ggttcgagtc 153660
cgacctcggg taccattgaa ataatagccg atactgctgt attggctttt ttttataaat 153720
atgtatataa gtgcactatg ttttatacaa taacactagt catctaatta attggccaat 153780
tgaattggat aacttctaca tctttattat tacatcatat gacagtgatt tttgtcgttt 153840
tttggtttaa taggttattt tttaaagttg tttggaaatg tgatttaaat atgatactat 153900
taggctgaca gtgaaagagg gataaataat tatgaaagta ttaaatgttg gatcgttaaa 153960
tattgaccat acatatcagt tagaacgaat tgttgcccca ggagagacaa ttacatctaa 154020
acaaatgagc gtatatgctg gtggaaaagg tttgaatcag tcaattgcta tagctcgagc 154080
agggatagag gtatatcatg ctggtaaaat cgggattgat ggacagtttt tgattgaact 154140
ttgcaatgat agtggagtga attctacttt tattgaaact ggcgtgatac ctaccggtaa 154200
tgctattatt caagtaactt cgcaaggaca aaatagtatt attttgtatc ctggagctaa 154260
tcgaagttta gataaagctt ggattgacaa agttctgact gaatttagta aaggggatat 154320
attattactg caaaatgaag tcaatttaat cgattattta attattgaag gtaaaaagaa 154380
agggatgaat atttttttaa atccttcacc atacgatgag tatattgata aatgtgattt 154440
atcattagtc aatacttttt taatgaatga agttgaaggt gcccaaatta ctggatgtta 154500
tgaccccgag tgtattttaa caagaatgaa aaatctttat ccacaggcta aagttgtttt 154560
aactctggga caagatggag tatattttca agataaggag cagcgcgtgt atcaacccgc 154620
acgaacggtc aaagcggtag atacaactgg agctggagat acttttacag gatattatat 154680
agctgctgta attgaaggta aaagtgcaat tgaagcattg acttttgcta ctaatgccgc 154740
tgcgttagca gtcatgaaag ctggcgctgc aaatgcaatt ccaaaacgtc acgatgttga 154800
aaaatactag gatgatttga tggataggta atgaagaaag tagtgaaata agatgaataa 154860
tagtagaacc agagaagaat tatttttatt tagggatttg gcaaaaacaa atatgactga 154920
attcgaacaa ttgatttcta tttcaattgg agcagttgga aaaattgttt atgatccaca 154980
gtttacagta atatattgta gtgagggaat ttctaaattg attggagttg attttattgg 155040
cagtggtgaa agatattttt cgagcagtca gtttattcat gacgatgatc gtgaatatgt 155100
atatcaagaa atcggcaagt atgttaattc taaagagcca tttagtttga aatatcgttt 155160
aaaatgttca aagggtaaag aagcttgggt gcaagctaaa ggaatttttt tagatgaatt 155220
atatgaggat aaagacccta taatgtatat ggtttatact gatattacgc cattagtaga 155280
agctaatgag cgcctagaac aagaaattca acggtatcag atttttactg agtttgttca 155340
agaatgcttt tttgattatg aaattggata tgatagtttg atgttttatg gaagtgatgt 155400
taatgataaa aatgatcaag aaaactggta taatatttgg agaataaaca aacgattaat 155460
tttagaacat ttttaccaaa ataatcatca tcttgataat gatctagaag ttgatttaat 155520
cgataaaagt aaatgctggt gtcattttcg tgcgaaagga atttataata cttatcacga 155580
tttagttaga atcgttggaa caatgaaaaa tatccagtcg gaaaaagagc gggaatcaag 155640
acgcaaagag tatgaagaaa aattaaaaaa taaggcacat tatgatcata tgacaggttt 155700
gctaaatcgt tttgcatgtg aaacaattgt taatcaagtg ttagatgaag gattggaaaa 155760
tgtaacagga gtagtaattg atgttgataa ctttaaagaa ataaatgatc tacatggtca 155820
ttatattggt gatcaagttt tgattaaaat aggtgaatta tttcaaaaat attgtcgcag 155880
tgatgatatt gctgcgcgtc ttgggggtga tgaatttttc ttgatgtttc ttgggcttat 155940
gcagcaagat acgattcgag caagattaca aacaatgcat caagagattc ataatattgc 156000
tcgagagcta aaactaaaag taccagtatc tgttagtatg ggagttacta aaatatattc 156060
aacggataaa acctttgatg atatttatgt ccgagctgac gaaacaatgt atcaagcaaa 156120
attatcaggc aaaaatacat tgatttgttt taatgaggaa taataaaacc ttaacagata 156180
aataaaatta tcgttaaggt ttttttcgaa acatcttttg ttgcttggct agatcagact 156240
ggctaactaa tttctttatt tcttgaacaa attcttgctg ctgaatcggt gtgagacgat 156300
gataaatatt gattaattca taattatgaa tatatatttg agatttttca gcttcataac 156360
attcgtcacc gattgcgctt aaatagccag attgacttaa tagatcaact aaactcattt 156420
caaaagcgtg agctatttta acaagtgatg gtaaagaaat attataagaa acgccacgat 156480
ttcctaattc gatattacta atggaggatg ctgataaacc ggttattttt tctaatttgg 156540
attgcgacca gccttttgaa aggcgagtac tttttatata tttaccaatt aatgctatat 156600
caatattttc cataatacgc ctccttttaa caagattata acgtacttaa actattgtga 156660
ccgccagaat tatgtagact tatatggact ataaaataga aataaaaaaa ctttttatta 156720
aaaaagattg acattattca ttctattgta tacaatgttt tcaacaacat ctgatataaa 156780
tactgtgaaa agaaatagta ggtattcaaa atagtttaga gagctcttgg ctggtgtaaa 156840
agagtctatt agagaatatt gaattcatct tggagtagag gactgaatcg ttagtagtag 156900
gtctctccgg caacacccgt taacgtgtaa gagtatgaac tatttgatta gcgtactcga 156960
tgaggttagt gtagcaatac attaataaat taaggtggta tcacgaagca taagctctcg 157020
tccttttata ggaagagagt tttttattta tatacagagt tgaaataaaa caaaagggga 157080
tagaaaaatg attattgtaa tgaaaatgac agcgacagaa aaagatgtcg aaaaagtatc 157140
aaaaatggtt actgacaagg ggttaaatgt tagtgttgta aatggaactg gtcaatcagt 157200
tatcggaatt attggggata caactcaaat tgatcctaaa gcaattgaag tagatgaagc 157260
agttgatcat gtaatgcgtg tatctgagcc atataaactt gctaaccggg cttttcatcc 157320
tgatgatacg atcgttgatg ttgctggtgt taaagttggg ggtgacaacc ttgctttgat 157380
tgctggtcca tgttctgttg aaagtgaaga acaagtaatc gagattgcta aagctgccaa 157440
agctgccggt gctaatattt taagaggagg cgctttcaaa ccaagaactt caccgtatgc 157500
attccaggga atggggtctt ctggtctgga tattcttgtt gcagctaaag aagcaactgg 157560
attgccaatc tgttcggaac tgatggatgc ccagtattta gaagaattca atgagaaagt 157620
agatctaatt cagatcgggg caagaaatat gcaaaacttc gacctgttaa agaaagtggg 157680
agcaggaaca aagaaaccaa tcttattaaa gagaggatta agtgcgacat ttgaagaatg 157740
gatcatgtca gcggaatata tcatggcaaa cgggaatccg aatgtaattt tatgtgaacg 157800
aggggtaaga acatttgaga catatacaag aaacacgttg gatttacagg ctataccggt 157860
agtaaagaaa ttaacacatt taccaattat aattgatcca agccatgcag gagggaaatg 157920
gtggttagtg gaaccaatgg caaaagcagc agtagcagca ggagcagatg ggttaatgat 157980
cgaagtgcac aacaatccgg agaaggcact gtgtgatgga ccacagtcat taagaccgga 158040
aagatatgaa gaattattaa aacaaatttc taaaatagct gaagttgttg gaaagaaagt 158100
ataattaatt aggaggaaat ataacgatgg aaatgacagt ttcattaaaa gaaaatagct 158160
atccaatcta tattgaaaaa ggaattttaa accaagctga taaatatatc aaggagatat 158220
atcaaggtaa taaaatcatg ataatttcgg atgatcaagt ttatcattat tatggtgatt 158280
tattaacaaa cgttctaaat aaagaataca ttgttgagca tgtaacggtt cctcatggtg 158340
aacagtctaa acgttttgat attttaccat cgttatataa atctttatta gattttaaat 158400
taacaagaac agatttaatc atcgctttag gcggcggtgt tattggggat ttagccgggt 158460
ttgttgcagc gaccttttta cgaggtgtta aattggtcca aatcccaact tcattattag 158520
cacaagttga ttcttcagta ggggggaaag tagcagttga tctaccagaa ggaaaaaact 158580
tagtgggggc tttttatcat ccgagaatgg ttttgattga tccaaatact ttaaaaacat 158640
taccagagcg ttttattaat gacgggatgg gagaagtaat caaatatggc tgtattaaag 158700
ataaaagttt gtttgataaa ctaaatagtt atgataactt tgaacagtta tacatggata 158760
tcgatgaaat aatttatcgt tgcattggta ttaagcgtga tgtagtcgaa agagatcagt 158820
ttgacttcgg ggatcgttta ttactgaact ttgggcatac acttgcacat gcaattgaac 158880
aatattatca ttatgagaaa tattcacatg gtgaagcagt tgcaatagga atggtacaat 158940
taactaaaat tgccgaagaa aatgatttat caccagtggg gactagtgat ataataaaag 159000
aaatttgtat taaatataat ttaccagttt atagcggatt aaaaacaacc gacttactgg 159060
aggcaataag tcttgacaag aaaaatatta ataaaaaatt atcgttagta ttgttaaagg 159120
aaatagggga tagctatgtc tatcaaagta atctttcatt aattcaagca aaggataggg 159180
tatagaatga cagcagtaaa aattacaccg actaaattaa gtggtgtggt ccaagtacca 159240
ccgtcaaaat cattagctca ccgagctatt atatgtgcta gtttagctaa aggaatcagt 159300
cgtatcgata atattgaata ttctaaagat attcaagcaa caattaaagc aatgcaatca 159360
ttgggaacca aaatagagaa atatgatgac tatttaatca ttgatggcac aactacttat 159420
acaaagcaaa atagtgagat tgattgtgaa gaatctggat cgacgctaag gtttatggtt 159480
ccaattgcaa ttgttgagga aaataaagct cattttgttg gacgcggtaa tttggggaaa 159540
cgaccgctaa atacttttta tgaaatattt gagcgtcaaa atattggtta tctttataaa 159600
gaggatatcc ttgatctata tgtaattggt aagttaaaac ccgatcatta taaggttcct 159660
gggaatattt cttcacagtt tatcactgga ctgctatttg cattacctct attagatggt 159720
gattcgatta ttgagatcac ttcaccgttg gaatcaaaag gatatattga tctaactttg 159780
cagatgttaa atcaatatgg aattaaaatt gtcaataatg attataaaag ttttattgta 159840
atggggaaac aagaatacca ggctcatgac tatcgagttg aggcagattt ttctcaggcg 159900
gctttttatc tagttgctgg agcgattggg aatgatgttg tattaacaga tttgaatctt 159960
gattcgttac agggagataa agcaacttta gaatttcttg aagccatggg ggctaaaatt 160020
tctgtagtta gtgatggtat caaggttacg ggtgaaaact tagcagcaac aattgttgac 160080
gctagtcaat gccctgatgt tatacctgtg gtttcagtag ctttagcttt agctcaaggt 160140
aaaagtgatg ttattaatgc taaaagattg agaattaaag aatgtgatcg aatcatagca 160200
actcgttcac agcttaatga attaggtgga accgtcacag agttacctga tggaatgacg 160260
attcgcggtg ttaatgagtt tactggcggt aattgttcta gttttgcgga ccatcgaatt 160320
gcaatgatgt tagcaattgc tgctactcgc agcagtcagc ctgttgttat tgataatatg 160380
gaatgtgtag aaaaatctta tccaaatttt tgggaagatt accagtcatt aggaggaatt 160440
attgatgtca tcgacgtgga aaaataatat tgagataaca atttttggag aatctcatgg 160500
aaaagcaatt gggattgttt taggaaatct accaagcgga atcaagattg atttagagga 160560
agtagccaaa gaaatgaaac gtcgtgctcc tggacaggat aaaatgtcaa ctgctcgaaa 160620
agaagctgac aaggtagaaa taatgagtgg gttacaggat gatgtaacga ctggtgcacc 160680
attatgtgga ataatttata atagtgatca gcattctaaa gattattcat tattaaaaga 160740
aaaaatgcgt cctggtcata gtgattatcc agcttttatt aaatatagag gatttaatga 160800
tgtacgtggc ggtggccatt tttcaggaag aatcactgct ccggttgttt ttgctggggc 160860
tatagcaaaa caaattttgg caaaacaggg gattcaaatt ggagcacata ttctaagtat 160920
taaaaacgag tatgatgaaa attttgatat gcgtttatca actaagacac ttgaatattt 160980
acgcagacaa cattatcctg tcattaatca agaaaaatat gaaaagtttg ttaatattgt 161040
tgatgctgca cgaatggatc aagactcagt aggtggcaag gttgaatgtg cgattattgg 161100
tttaaaacct ggtcttggtg aaccgttttt tgattcaatt gagagtcatt tatcaagttt 161160
gttattttca attccagcag ttaaatcagt agcttttgga aatgataaga ttagtgaatt 161220
atttggtagt gaagctaatg actgttacta ttatcaagat gctctagtaa aaactactag 161280
taataacaat ggtgggatta ctggtggaat ttctaatgga atgccagtcg tttttacagt 161340
tggaatcaaa ccgacacctt ctatttctaa agaacaaaaa acgattgatg taaaaaaaca 161400
tgaaaataca acattaggag ttcatggacg tcatgatcct tgcattgttt ttagagcaac 161460
tgtagttgtc gaagctatgg cagcattagc aatgttggat ttggtgaggt aatttatgaa 161520
agatttagaa caatgtcgtc gtgaaatcga tgaaatcgac caacaattga ttaaattatt 161580
tgagcagcga atgaatgtta gtaaagatgt tgtcacttac aaattagctc atggattaga 161640
aatttttcaa ccagaacgtg aaaaagcagt aattgaaaaa aatgctgcac ggatgatgaa 161700
tccagagctt gctgattatg cacgtaattt tatgcaagat gttatggatg tcgggaagag 161760
ctatcaagct acttttattc ctctaaataa tctttataat ttagctgcac caaaacgaga 161820
aaatattaaa gttggatatg caggggtgcc tggtgctttt gctcatcagg cgatgttaga 161880
atactttgga aatgtagaaa atactaacta tgttaatttt cgtgatgttt ttgaggcttt 161940
aaaaaatgcg gaaattgatt atgggattgt tcctctagaa aattcttcaa ctggagcaat 162000
taatgataat tatgatttag ttcgggatta cgatttctat attgttggtg agcacagtgt 162060
ctgtatttca caacatttat tagggattaa gggggctaaa attgaaaata tcaaaacagt 162120
ctatagtcat ccccaaggaa ttcagcagtc agctgatttt ttaagaaata atcctcaaat 162180
gttgtctcaa gacttttcga atacagctgc agcagcaaag tatgtaagtg aatgtaatga 162240
tttatctaaa ggagcgattg cttcaaaagt ggctgcaaaa ctgtatgatt tagaagtatt 162300
acaggaaaac attcataatg aaaaaactaa taatactaga tttattattt ttgctaaaca 162360
tcttgaagat catcctcaaa ctgatcgggt gagtattgta tttacattac agcataaagt 162420
tggggcttta tatggggtgt taaaagcaat taaagatcac caaataaatt tatcaagaat 162480
tgagtcgcgt cctataaagg ataaacgttg gcaatattat ttttatattg attttgaagg 162540
tagtcttcat gatgataatg tcaaattggc attagaacaa atgaaaacaa attgtcttac 162600
cttaagagtc ttaggcaatt accatcatgc atagggagaa aagatgaaaa atattgtatt 162660
aattggcatt atgggatgtg gtaaaactac tttatctaga atgcttggtg aaaaattaaa 162720
cagaccagtt attgacattg acgaatatat tgttgaaaaa tatcatcaaa caattccaga 162780
gatgtttgaa gttagtgaaa catattttag gaataatgaa actgctggat gtaaagatgt 162840
ttccgactta aatgggcata ttatttcaac tggtggaggg gttgttttaa gacctgaaaa 162900
tattaaatat ttaaagcaaa atggaataat catttatatt gatcgaccta ttgataatat 162960
tttaacggat gttcaagtta caagtcgtcc tttgttaaaa gagggcccac agaaactata 163020
tgaattagat aaacaacggc atcagcttta tcttgaagct tgtgatcatc gtattgttaa 163080
tgatgatact ttagaaaata ttactgataa aattattgag ttaataacta aaaataagtt 163140
tgaggattaa tcctcaaact tatttttttc tttatttagt tttttatttg tatacatttt 163200
agcatctgcg cgtttgaatg tatcctttaa atcatgatca attttaggat cataaacagc 163260
aaaaccaata gagattgata atttttcatc agtttgtttt gaaagctctg tttgaattgc 163320
tgttacaaca gctttgattt gctgtttggc atcatgatga ataagaatga taaattcatc 163380
cccgccaaaa cgataaactg tatttttttg gacatgtttt tcaagaattt tagcaacttt 163440
tttaatatat tcatcaccag tacgatgtcc atatgtatca ttgatttttt ttagatcatt 163500
aagatcggta ataattattc cggtattgtg cttatgtgtt gataagtttt caaaatctat 163560
ttcaaaagca ttccgattat gtaaatttgt taagtaatca gtattagcca tatctttaaa 163620
acgaggattt gaaattcttc taaatgatag aacggcaatg atagtagcga taagactagc 163680
cataatggca atcaacggtg taataattcg aatttgttta aaggcttcaa attgatgact 163740
agcatcaaat tcaattccta gcacgccaac tacttttcct tcgtcgtgta tagggtaata 163800
tgaaacaaaa atgggacccc aggtagtttc cttaatctga tctggcaaaa taattttatt 163860
ttttaatgct gctttaagct caggaattat ttctttttca attttatctc caggataacg 163920
aaaatctgga cttgcagttg gcagtccatc gacaagatag atatattcgc cttcatctgt 163980
catttttgca gtatagagat acaaaacatt tgttgcattt tttacatctt ctaatttttg 164040
ttttatttgt ttataagtat catttttcat atcaagagaa aaattatgat taaaagtatc 164100
tttgtctaaa taattttcta cataatgata tatcgtgttt gaacgttctt ttagactata 164160
gatcatatca tcgtgagtga ttttataatt aaaaatatag acacaaaaaa aggatgcaca 164220
aacaattatg attgtaatga tcgatacttg ataatctacc cgatcgagcc gtttaaattt 164280
cattggtttc aacccctttc tttgattcta ccataaattg actaaattgt gtttagatat 164340
gctgattata aaaccaaata ttgtcagtca aagtaataat attcatcctc atcaaaatgg 164400
tatttatgat ataatgtgtt aaggtgatag agatgcagtt agaaaaacaa atatatattg 164460
ataaagattt accagctggc tggaaaccat attatatttt tttaatgaaa gtaaacaatg 164520
aaattgtggg gcgaatgact ttacgagaag gtagttgtga agaacgatac tatgatggac 164580
atattggtta tactgttgag cccgaatttc gtgggcatta ttatgcgtat caaggagtcc 164640
agttaataaa accaatagcc ttaaaactag ggtttaagga actgataatt acttgttcac 164700
caaataattt agcttctaaa aaaacgattt taaaattaca agcacaatat ttagaaacag 164760
tagaaatacc taaaaaatat cggaaagatt ttgaagccgg tgaaacaatt aaagaggttt 164820
atttaattaa attataagga ggaaaataat gagatttgtt catattagtg atattcattt 164880
aggaaagttg ttatatcaac aaaatttatt agaaattcaa gctgatttac tgaatcaagt 164940
ttgtgattat ttagtcgata acgaaataga cgttttagtc atggctggag atatttatga 165000
tcggagtgtt cctagtaatg aagctattga tgttttaaat gattttttaa caaaagttat 165060
tttaaagtat cacaaaaaag ttttgatgat agcgggaaac catgatagtg cgagtcgatt 165120
aagttttgtt agcggattgc taagacaaga aggattgtat attgaagcat atccggctaa 165180
acaaatgaag ccgatagaaa ttgaaggggt taatttttat ttaatgcctt tttttaaacc 165240
atcttatatt cgctatttgt atgaagatga acaaattgtt acatatcagg atgcttttcg 165300
atgttatctt gaacatcaaa aaatagattt tactaaaccg aatgttttaa ttacccatca 165360
atttattgct ggaaatagtg aagttatgcg aagtgaaagt gaaacagtat taagtgtagg 165420
tggaacggaa attattgatg tttcattagt taaacaattt gattatgtag ctttggggca 165480
tatccatgca cctcaaaaaa tatcaactga aactattcgc tatagtggca gtttaatgcg 165540
ttattctttt gacgaagtta atcaaactaa aagtatagtt gaggtaacga ttgataataa 165600
aaaagtatcc tatcagcttg tatcattaca acctaaacaa gacttaatta aaatcactgg 165660
gagttttgat gaaatcatgg cagattcgtt tgccattaat aataatgatt ttattgcagt 165720
tgaattaaca gattcaatgt tagtgcctaa tgcgattgat tatttaagaa caaaattttc 165780
aaatgtattg cagattactt atccaaaact aataagtaat gaaacgagta ataatactaa 165840
agctgatcct ggatttgaaa aacttgattc agttgcttta tttgaacaat tttatcaaaa 165900
aataaaaggt acagaactaa gtgctgaagc caaacagatt gttacagaaa tcatgatggg 165960
agggaaagaa aatgttgcct aatcgtctta ctatgtcagc atttgggccg tatcatcaag 166020
tagtgacaat tgattttgag ccatttattc aagatggttt atttttgatt actggtccta 166080
ctggagctgg aaaaacaatg atttttgatg ctattatgtt tgctttgtat ggagtatcaa 166140
gtgggagtga acgtagtagt gaacaatttc gaagtgacca agctaatcat gatactccta 166200
cttttgttga acttgatttt attttacata atcagcatta tttaattaag cggtcaccac 166260
gatatttatt agaaggtaaa aaaacaccta agttacccac tgcattatta acattgccgg 166320
gtggtaaaat gatagaagga atcaaagaag ttaattataa aattaaagaa atcctgggaa 166380
tcgatgataa gcaatttaaa caaattgcta tgattgccca aggtgaattt acaaaactta 166440
tttatgcagg gagtgaagag cgagaaaaag tattacgcaa tttatttaag acagataatt 166500
ttagatgctt agaagaacag ctgaaattgc gagttaaaga atataagagt aaatatgatt 166560
tactttttaa acaaagagag atgttgttaa agagtcttga tgtagaagat gagaaaattg 166620
atttagatga atatttggat tcactagaaa aaaagataaa gattaaagcg atggagtacc 166680
agcaaaatgc acaatattat gagcaaaagg caaaagagct aaatgtcatt gagataaata 166740
atcgtcgctt agaatatcta gatgatttaa aaatccagct atcgaattat ttaagcaaag 166800
aggattatta tcgagaatta gagaagatga tcaaagattt aaaaagagcc aatcaacttc 166860
aaaatatcta ttcactaatg attagtagta aaactaaatt agctaagcta agagaaaaag 166920
aaaaagtctt aaatgaacgc ttatcatttg caaaaaatga tttaaaaaag caggagaaac 166980
agtatgcttt agtctctaaa tatcacgatg aagttgctca gggacaaatt gaattagaaa 167040
aaatggtaga actaaaacaa aatgttttag tatatcaaaa agatttaaat cagggaaata 167100
acttaaggaa acagattaaa gtaattgaga gtaaaaatat cggtttaaat gatagattac 167160
aaaaaagtgc taaaattatc gaacgagata gtaatagtat tgctcattta gataaactta 167220
agggtgatta tgagttgata aatcaaaatt atcaaaaaat tcatgctcat aaacttgaga 167280
ttcataactt aagctctgat tatgataaat ttttaagaga agaggaacat tgttatgagc 167340
ttcgtgaaca gtatcaaaaa attgaagaaa aatatttgaa tgaaaaaaat aaatatgatc 167400
aaatggaaca tcattttaga tcaagccagg ctggtatttt agcaagcagt ttaaaggaaa 167460
atgagccgtg tcctgtttgt ggttctttaa accatccaca attggcagat tttgatcaaa 167520
aaatagttta tcaagaagat ttaaaaaaag caaaaaagaa ttttgataag tgtagcgaaa 167580
cacgaaatga tatttataat gctttaatat taaaacagca agaagttact ttattaaaga 167640
aacaaatgga aaatgattgt cagcgcttag gaattgaaga agaattgggg aaagaagttt 167700
ttattaaagt attaggaaag atcaatatcg atgaaaataa attattaaaa caggctaaag 167760
aattggataa tgaaattatt tatttaaata acttaaaaat aagtttagct aatcatcaga 167820
aggatctaga tttattagaa cagaatattc aaaaaaataa tgcacaagta caagcttata 167880
aagatcaatt aaatcaagtc attggacgaa tggaacaaaa taaacaatta aaagatttaa 167940
cgcatcatca ggttgatcag caaattgaag aaaagcaaaa agaattgtta ggtttgacta 168000
aaataattaa agatattgaa gaaaaatacc gttctataaa tgaacagatt attcaattgg 168060
aagctcaaaa taggtcgtat tgccagcaaa tcaaagatga ggaaaataat tatcagcaag 168120
tactaagaga atatcgtggg aaactgaata gtttatttac agatgaaaag gaatttttag 168180
agattattaa aaacgtcagt cagcttgaaa ataaagaaaa ggagtatcag gcttatttaa 168240
ttgccaagga ttctttgaat aaacaaattc atgaattgca acttgaatta aagggaattg 168300
aagttataga tgttgaagtc gtaaaagaaa aactaattat tttaaaacaa aaattagatt 168360
ctgctttaaa tattttaaat aatttaaatg cccaattaat gacagtaacc agtacaatca 168420
agaatattaa aaatattgat caggaattaa gtaatagcca tgatatttat caatgttatt 168480
tagatttaag tgaggttaca tctggaaaaa acagctatcg aatttcattt gaacgttatg 168540
ttttagcggc atattttgaa aatattctag tttatgctaa taccctgcta aaacgtatgt 168600
cgcaaggacg ctatcagctt tatcgtcgtg ataaccgctc taaaggggca ggaaagcaag 168660
gactggaatt agatgttctt gatttagaaa gtggactttt acgtgatgtt aaaacattgt 168720
cgggtggaga gtcttttaaa gcggcattat ctttagcttt agggctttct aaaatgattc 168780
aaggttatgc tggagggata gaattaaata ctttatttat tgatgagggc tttggttctt 168840
tggatagtca atcattagat caagcaattg actgtttgat tgatattcaa caagatggta 168900
aattaattgg aatcatttcg catgttagtg aattgaaaga gcgaattgat cataaaatta 168960
ttctttcacg gaagaacaaa gaaacaaaga ttgctattga ataatcactt tattaatagt 169020
aaaataggga aagattataa tgaaatgagg agaaataatg gcaaataata agaaaaatga 169080
tgcaataacg gcgatggaag acgattttgc tcagtggtat actgatgtct gtcgtaaagc 169140
agaattaatg gattacagca gcgtaaaagg atttattatc tatcgaccat atagttatgc 169200
gatgtgggaa gcaatccaac aatacatgga taaacgtttt aaagaaacag gacatgagaa 169260
tgtttatatg ccgatgctta ttccacaatc attattacaa aaagaatctg atcacgttga 169320
aggatttgca ccagaatgcg caatagtaac gaaaggtggg ttagatgatc tagaagaaaa 169380
tttgatcatt cgtcctactt cagaaacact tttttgtgag cattatgcta aaatagttaa 169440
ttcatatcgt gatttaccaa aattatataa tcaatggtgt tcggtagtac gttgggaaaa 169500
aacgacaaga ccatttttaa gaggatctga atttttatgg caagaaggtc atactgttca 169560
tgcgagtgaa acagaagctc gggctgaaac attgcaaatg ttagaaatct atgaagatac 169620
tgctaaaaac ttattagcaa tcccaatgct aacgggacgg aaaactgaac gtgaaaaatt 169680
tgcaggagct gaagaaactt atacgattga agcactaatg catgatggta aagctttaca 169740
gtcaggcact agtcattatt ttggacaagg ttttgctaaa gcgtttgata tgaaattttt 169800
atcaaaagaa aataaattag aatatgttta tcaaacatct tggggagttt caacaagatt 169860
gttaggagca attatcatgg ttcatggtga taataatggt ttagttttac cgccacgggt 169920
ggcaccgact caagtaatga ttattccaat tcaacaacaa aaagcagggg ttttagataa 169980
agcttatgaa attgaaaaac agctaaaaga agctggaata agagttaaag ttgatgcaag 170040
tgataaatca ccaggatgga agttctcgga agcagagatg cgtggcgtac cattaagatt 170100
agaaattggt cctaaggata tagaaaataa tgcttgtgta attgcaaaac gtaatgatgg 170160
aactaaagag aagtatgcat tagatcaaga actaattaat acaattgaaa cccttttaga 170220
cacaattcat gatgaaatgt atcaaaaagc attaaatcat cgcaattcaa atattcgtca 170280
agttaacaca tatgatgaat ttaaaactac attggaaact aaaggcggtt atatcaaaat 170340
gatgtggtgc ggtgatgagg cttgtgaagt taaaatcaaa gaagaaactg gagcaaccag 170400
ccgatgtatt aaagaagagg aagaagcatt tggtgatgtt tgtcctattt gtggtaaacc 170460
agctaaaaag gttgtgtatt ttgcaaaagc atattaagat acgaaatttt cgtatctttt 170520
ttgttgttag ttgacatatc aactaatgtt ggtataatag ttgacatatc aactaatgga 170580
ggtgcaaaat ggaaagaatt ggacggatta ttcatcattt agcaatatta aatcgaaatg 170640
atagtaatca aagattaaaa gagtatggat taacaagtaa tgaaggttct gtcctaatgt 170700
ttttgagtcg tcatagtaag gtttatcaag aagaattgat taaagaatta caaattgata 170760
aaagtgctgt aacaagattg ctccaaaata tggaaaataa agggttaatc aaacgaattc 170820
aatcgcctgt tgataaacgt ttttatttat tggagatgac agccttaggt caagaaaaac 170880
agcagatagt tgaccagaca tttgctaaaa aagattttat tttagtatct gggttgagtg 170940
aaaaagaaca agaagaactt cgaagaatgt tagatgtgat acaaacaaat ctaaaaggag 171000
gtaaaataaa tgaatgatga gagaatggga aataaaaaaa tccttccatt attaatagaa 171060
tttagtgttc cagcaattat tgggatgcta gttaatgcaa tttataatgt ggttgatcga 171120
atgtttattg gaaatgcccc acaattagga gcggtaggga ttgctggaat tacaataagt 171180
tatccagtta cattagtatt aatggcaatt tcattaatgg taggagtagg tggagctact 171240
cgtttcagca tttctttagg acaaaaagag aaagataagg cttcaatcta tcagggtaat 171300
gcaattgttt taacagttgt ttttgggctg atgtttactg tattagggaa tatttttata 171360
acacccatgt tagaagtttt aggtgctagt aaaacagttt tgccatatgc cagcgattac 171420
ttatcaattg ttttgtatgg agcagtattt cagtgtgttg caatgtgtgg gaataatttt 171480
tctcgggcac aaggcaaccc taagaatgca atgatttcac aattaatagg ggccggattt 171540
aatatcgttt ttgattatat tttaatcatt cagttgcata tgggaatgag tggtgcagct 171600
atagcgacaa ttggtggaca attcttaagt atgatttggc aactgtgcta tctatgttca 171660
aatcgctctt tgattaagtt agatatcgaa catatgaaac taaagctgat ctatgcgtta 171720
gatattatta aaacgggaat accagcattt ttaatgcaaa tggctaatag tgttttaaac 171780
tttattttga atagtacatt aggaatgtat ggtggtgata tcgcaatttc aacagtagga 171840
atcattacta gtttccaaac tatatgccag atgcctttaa caggtttaat gcaagggcaa 171900
caaccattga ttagttataa ttttggggca ggcaattatc atcgagttaa agaaacttta 171960
aaatatgcga ttatcggtgg tacaatgatt gcagttgtag gttttttagc agtacaattt 172020
ttcccggaaa ctataattag aatgtttaat ggtgaggcag aagttgtaaa actaggcaca 172080
aaggcaattc gaatttggtt cttattttta ccattgttag gggctcaaat catgactgct 172140
aattatttcc aatgtattgg taaaattaaa gtagcaagta ttttaaattt acttcgtcaa 172200
gtaattattt tgattccaat gattttattg ttagcgactt tctttggttt gaatggtatt 172260
ttctgggctg ttccaattgc tgatttagga gcgtttgtaa ttacaatttt ctgttttata 172320
aaagcaatca aaaagctaaa gtaaaaagat ttctactcta tagaataaga catgaaataa 172380
aaaatggatt attcatagag taatttattt tttatgaaaa aataataact ttattagcat 172440
tattccctaa aatcgacatt aaattctcat cagataaaaa agccatggat agaaatccat 172500
gacttacatg cctgattatt ttaacatttt aattgaagta attacaggct ggttagaagc 172560
ttcaacagtt ccattattat cagttactgg aacagttgta gcaattttgt caactacctc 172620
gattccttca taaacataac caaaaacagc ataatcccca tctagtgaag tagttgtttg 172680
atgcataata aaaaattgtg aacttgcact atcaggatca gatgaacgcg ccattgagat 172740
tgcaccgcga gtatgtttta aaggattttc aacaccgtta gaactaaatt cacctttgat 172800
tgtttcatca gaaccaccag ttccattccc ttttgggtca cccccttgaa tcataaagcc 172860
gtcaatgatc cgatggaagg tcaacccatc atagaaacct tctttaacta gttttacaaa 172920
attagttaca gtaataggtg cttcatcagc ttgaagttca actttgatta ctccataatc 172980
cttaacatcg atttcgattc gataattacc gcttaacaaa tctttggatg ctgttttctt 173040
atcttgttca tcattacttt ttccaccaca tccggctaag cttaatgcta atagcataac 173100
cattgtaaat ttaaataatt ttttcatatt atctccttat atctatctat tatttattat 173160
acaaaatagt gggtgggatt gtccatataa aaataatcaa aactgtcatg gttaaaaaat 173220
ataaaaatgt gataaaatga atgacaatga taaggggata aaatgagatg aaaagaattg 173280
ctttaataaa tgatgtaaca ggatatagta gatgttcgat tgcagcgcag ctgccgataa 173340
tttcagcaat gggaattgaa tgtgtttttg ttccaactgc aatcctatca gtaaacacaa 173400
tgcatccaga atattatttc gatgattata cggatcgaat gaatgattat attgaaacat 173460
aataaaaaaa tgaaggttag ttttgatgga attgctacag gatttcttgg ttcagaaaga 173520
caaatcgata ttgtcattga ttttataaaa acttttaaga aaaaacatac atttgtatta 173580
gtagatccgg taatgggtga tcatgggaaa ctttatccga cttacactac tgcaatgcaa 173640
gataaaatgc gtcaactaat accatatgcg acaattatga cacccaattt aactgaatta 173700
tgcgcacttt tagaggtacc atatccgcat gatataatta atcgggatga gctgattgaa 173760
atgtgtcgcc aattgtcaaa tttgggccca caaatggtcg ttgtaacagg gattagtatt 173820
ggtgacgaaa ttattaactt tgcatatgaa caagggaagg aacctgccat tatcaaagta 173880
aagcgaatag gcgatgatcg aagcgggact ggtgatgtta tcagcggtgt tattgcggga 173940
agttatttaa atggtttgaa tttctatcaa tgtgttgaaa aagctgcaaa ttttgcatct 174000
aggtgtattg agtatagtca agcagttgga gctcataatc atttgggact atgctttgag 174060
cctttcttaa aagaacttta ggaggaaaga aaatggtgat tttatatacg ctacatggta 174120
atggatatat tgatttaaaa gatctagata cgtataaggg aataacttgt tatgttaaca 174180
gcacaaacag atgtagttgt gcatgtactt tttgtttacg taatacaaaa gaaatgcttg 174240
aatcaaattc tctatggtta aaaagggagc cgactgtaga gatgattatt gcggaatttg 174300
aaaaatatga tttaacagca tttaaagaag tagtattttg tggttttggt gaaccgttaa 174360
ctcgccacga tgatttaatg aaagttgcaa aatatattaa agagaaaagg tcagatttat 174420
cgattagaat caatacaaat ggcttatcat caattacgtt agggcgtgat attgcgcctg 174480
attttaaggg agtaatcgat acagtatcta taagtttaaa tgctccaact aaggaagaat 174540
attatgaatt aacaagagcc tgttatggag ttgattcatt taactacatg ctccaattca 174600
caaaagcgtg taaaaaatat gtaccaagtg ttgttttgac agttgtagat ataatcgggg 174660
tggaaaaaat taaattgtgt caaaaaattg ccgatggtct tggagtagag ttaagagttc 174720
ggccgtttga agaataataa attgtatcaa gattataatt atgatagaat ttataacagt 174780
gaggtaatta taaaatgatg caattaagtc gtgaagaaag aatgttagat gtaaaaagta 174840
tgactaatgt tcgtgatttg ggtggctatg aaactcaaac tggtttttat acaaaaagtc 174900
ataaatttat tcgttcaacc aatccaagta agttatcaga tgatgagaaa gaatatcttt 174960
atgattatgg aattagaatg caagtagatt tacgaagtga ctttgaagtc gaacagttac 175020
caagtcaatt aacaggttat cgtgatattg aatactataa tgtcaattta atgcagtcta 175080
aagatttaaa tgttctccct agtgaagtaa caaattatca agatttagct ggtttttata 175140
tttttatgct agaggcaaat aaacagcagt ttaaagaagt ttttgaattg ttttatgatc 175200
atccatacga tgcaattatg tttaattgtt cagctggaaa agatcgtact ggggtgattg 175260
cggcattatt gttagattta gcaggttgtc atgattatga tattgttaaa gattattcag 175320
aatcatatga aaataatctt aaaataattt ctgaattgga acgtttggtt gatgatgcta 175380
atcgcgcatt tttagaatct gctccacaaa tgatgatgaa atttttggac tatttgagag 175440
aacattatgg aagtgctaaa gagtatttgg taagttgcgg tcttgaagaa gaaaagatta 175500
ttgaaattat agaaaatttt gtaatttaaa aaaagtaatt ctcctatttg agttgtatat 175560
gataatagga ggattttttt atgagaaaaa caaataaact gacatttaaa caaaaacaag 175620
aagcagtagc ggagctattt aagcagtttc accgagctaa attgaaattg tattgtttag 175680
aaaatactaa tttctatccg cagttaaata tcgggatgct tcatgaaaag aaaagtggat 175740
acaatgcttc aattgctgaa cgcttaaatc aacgaattga tgatagagat gaattggagc 175800
gagtggtggc agcatttgaa attgtgattc aagcattaag tcctgagagt caattaatta 175860
ttacaaatga atttgtttta cagaagaatc atgagtggtg gcttgaattt tatagtcgag 175920
caacttatta tcgtttaaaa acaagagcct tggaagaaat attattttat gtaaatattt 175980
cataattgtc atatattagc gctttttcct tgaaaagact ggtattttag atataataaa 176040
aaggtatttt taaaaaggag aaagacaatg cttgaaaaga tttttaaatt aaaagaaaag 176100
ggaacaacgg tcaaaacaga ggttattgct ggaattacta cgtttttagc aatggcttat 176160
attttagctg ttaacccgaa catgttaagt gagactgggc tgtcttatga tggcgttttc 176220
ttagcaacgg cactatcttc agggatcgca actttgatca tggggttatt agcaaactat 176280
ccagttgctt tagcaccggg gatgggagtt aatgcattat ttacatatac ccttgttttt 176340
tcaatggggt atagtcctgc agcagcattg gcagcggttg tagtatcagg aataattttc 176400
ttgttaattt cagttactgg ggtgcgtaaa gcaattatta atgcaattcc tcaacaatta 176460
aagcttgcga ttggagctgg aattggattt tttatcgcct ttattggact aaaaaatgct 176520
ggaatcatta ttggaagcga atcaacattt gtggcgttag ggaagttgac tgatccagtt 176580
gtattattag cagtatttgg ggtcttaata acaattatct taatggctcg taagacacca 176640
gcagcagtat tttatggatt ggtgattacc gcaattgttg gaattgtagc tggtttatgt 176700
ggtatcgagg gaatgccggc aatgccttca aaaattgttt caattgattt agatactagt 176760
gggtttggta tatttatgaa tggttttggt gagttattta gccatccgga ttgtattgta 176820
gcattatttt cattgttatt tgttgatttt tttgataccg caggaacatt aatttcagtt 176880
gcgaacaaaa ctaatttagt tgatgaaaat ggtgagttag ataatattga acaagcatta 176940
gttgctgatt ctacaggaac agttattgga ggaattctag gaacctctac tgttacttct 177000
tttgttgaat caacagctgg ggttgaagct ggaggaagaa caggattaac tgcttgtact 177060
acagcaatat tattcttctt atcaatttta tttgctccag tacttagtgt tgtaactagt 177120
gcggttactg ctcctgcttt agtggcagtt ggaatttcca tggcaactca attaggtgga 177180
attgattggg atgatatcgt tttcgctgca tctggtttca tcacagtgat catgatgatt 177240
ttaacttatt caatttcaga tgggattgca tttggtttta ttgtttatgg tattactagt 177300
gtaattgctg gtagatctaa agaaatcaaa ccgattgttt gggctttaat tttaatcttc 177360
gtagtatatt ttgctttaat atagtggaaa gatacttgtg aactatttta agtaatagtt 177420
tgtcaagtat cttttattat ttaataaata tgatttaatt taaagtttta ttaataatat 177480
atgtgggtta gccccttgct ggctaagatt atttttcaat actttctagt tttgaattga 177540
ttcaatcagc tcggtaataa agcaatttga gtggcaaggt caatcgttgc aattaaatct 177600
gtgtttcgtt agtataaaaa tgtaatcaac tattttgatt ttttactatc taagtaatct 177660
tgtttattaa tttaccaaaa gtagtaacat ttataattac tatatttctt attttattaa 177720
tcatttgata ttagagaata atattatttt ttcctaatag ctattcaatt atatcaagtg 177780
ttcaatttga caaagcaagg taattgtcaa tggaaactta ctttaaaaaa ataaacttag 177840
tttctcggca actatttcta atataatatt caagacttta attatttaca aaaatccaaa 177900
aatttaaata taaggcaaaa agtatccaac ccatgtaagg aagtaataaa aaagctgcta 177960
aaggacggat ttgataaaat aatttgataa gaatagcaac tagaatacat agtgtaatca 178020
atattgctag tgctaataaa aaactttggt aattaaaaaa agcgataggc catgcaaaat 178080
taatcagtag ttgaaaataa taaataataa gagcagtttc tttattttta ctattacttc 178140
gatgaattag ataacttgct aaaccgatta aaatataaag aaatgtccaa acgattggga 178200
atagatatcc aggcggagag cacttaggaa ggttaactgt ttggtataca tccattgcat 178260
tcattgtaaa aattgcactt aaagcaccga ttcccagaga gattgataga tttaatataa 178320
tatatttgta ttttttcaat tttatcacct atattagtat agacagatta tcgaaaaata 178380
ttaaaaatct taagaagtga taaagaatga taaatttttt tctaatatag aaaaaaacac 178440
ttctatagaa aagcgctttc atgtataata atagagtgag gtaagagaat gaaattagta 178500
tcatggaatg ttaatggaat tagagcctgt attacaaaag ggttctatga tgttttaaaa 178560
gaaagtaaag cagatatttt ttgtgtccaa gaaacaaaga tgcaagaagg tcaaattgaa 178620
ttagaaaagc atggatatta tacttatatg aatagtgctg aaaaaaaggg ttatagtgga 178680
actttagtgt tttctaaaga aaaaccatta aattatagtt atggaattgg tatcgaagaa 178740
catgaccatg aaggccgcgt tgttacgctt gagtatgaaa aattttattt agtcaattgt 178800
tatactccta atagccaaaa tgaattgaaa cgattggact atcggatgca ttgggaagat 178860
gattttcttg catacttgaa gtctttggag aagagtaaac cggttatttt atgtggtgat 178920
ttaaatgtag cccatcaaga aattgattta aagaatccta aaacgaatcg taaaaatgca 178980
ggtttttctg atgaagagag agctaagatg acaaatttat tagaaaatgg ttttatagat 179040
acgtatcgat atttatatcc tgatcaagaa ggtgtttatt cttggtggtc atatcgattt 179100
aatgcccgta agaataatgc tggatggcgg attgattatt ttattgtttc agattgttta 179160
aaagaaggga taaaagaagc gtttatttgt actgatattt tgggcagtga tcattgcccc 179220
gttggattag aaatagattt ataagatatg ttaaaggaga ttgtgtcaat ggcaccagtt 179280
acattattat catttcttac tcttttagga ataaccgtat ttttctttgc atgtgtagcg 179340
tacaataaaa taaaaaacaa gtaatgattt atttcattac ttgttttttt aaattgaaat 179400
aatccccatt gttgataaga ctgaactaat taatattatt aataggccag ggacaacaac 179460
atatttcata caaaatagat aagctttttt acgcttgaat ttagaactgt attcaacttc 179520
gtcagtaact gttttaaaac cggttacttt gatgataagt agacatgtac aagctgcaga 179580
aattggcatc atgattgagt ttgtcataaa atcaaagaaa tcaagaatac ttaaaccaag 179640
cggtgtaatg aaatctaaaa caccaaatcc aagtgaacat ggaataccta ataaagcaat 179700
tcctccaaaa ataagaacac agcatttttt tcttgaaaaa tcatatcgat cttgaataat 179760
tgaaacacaa cattccatta atgaaattgc tgaagttaat gctgcaaaca gtactaataa 179820
aaagaatact aatccaataa tgttaccaaa tgacatactg gcaaatactt ttggcattgt 179880
aataaacatt aaggaaggac cggcgtttag tgtatctgga tttccaccag aaaaagcaaa 179940
tactgcgggg ataatcatta aacctgctag aaaggcaatt aatgtatcca ttatctctac 180000
ttgagtaatt gattgttcca tatcaatttc acgtttcata tatgaaccat atgtaaataa 180060
aattcccatc ccgatagaca acgaatagaa catttgtccc atagccgcta ctactgtcat 180120
gattgaaaaa cgcgagaagt caggaattaa atagtattta accccttcaa tagcaccagg 180180
tgtaaataat gcatataaag caatgaatag agccattgca actaaagcag gcattaatac 180240
tttactgcat ttttcaattc ctttttcaac acctagcata actacgccaa ataccattcc 180300
agcaaagaca agtaaccaga tgacaggctg tagtgttgaa gatgaaaaac cagtaaaata 180360
ggtatcacta actaagctgg cagaattgtt tgtaataaat tcaaataaat atttacaaac 180420
ccatccccca acaacacagt agtaaggtac gatgagcatt ggcacgatgg catttagcca 180480
accaccaaat tgaagttttt ttgcacccaa ttgtttatag gctgcaatcg ggctcttttt 180540
tgtttttctt cccaaggcag tttcactaat tagcaaagca aaaccaaagg taatcgctaa 180600
aataaaatat gtgaataaaa aagtacctcc accatattta gctgctaaat aagggaaacg 180660
ccaaatattc ccgagcccga cagcagaacc agctactgcc ataacatagc ccaggcgacc 180720
agaaaagcta cttcgcttgt gttttgtttc catttttatc tcctattatt aaattttcat 180780
gccttttcat tataataaaa tttgtctata aaagtcaatt aaatggcact aaataggatg 180840
tttttgttat gattttgtta atgctgagtt aaattagatc aatagtgtta tgatataaat 180900
ataaataagt aaagaaggga taaaatatgg cacgaataat tgcaattatt atggccttat 180960
ttggtcataa agggcattcg taatttcggt attaaaaaag atatctacgt ttagatatct 181020
tttttatata ttgtaatacc atctttaatt gtctcaatga tcttaatctg acgaatttcc 181080
tcgattgcaa ctttgcaagg attacgatca aggattaaaa gatcagcttt ttttccttct 181140
ttaatagacc ctttcaagtg ttcttcaaaa tattgataag cggcattaat tgttactcct 181200
tttaatgcat tgtagacaga tatttgttca tctgtcccca aagtaacccc gtttttggtt 181260
tggcgtttta cagcacacca aatcgtttct aacatgtttg gctcaataac aggggtatct 181320
tgatggaagg tataaggtaa atctaatttt aaagcactat gaacacaaga aatagattca 181380
gcacgttgtc caagattacg gcggtgaata tcaccccaat aatagatatg agcaatgaag 181440
aaactaggaa tcattccaat gctttttagc cgcggtagtt gatctggtct taaggtttga 181500
ctatgaatca ttacagggcg tagaggtgtg tactgatcat taaaggcatc aagtagttga 181560
ttggaagcag catcaccgtt acaatgagtt agtagttgcg ctttatcatt aatagccata 181620
tctacgaatt ttttaacatc tgaatctaag tagatcggat atccacaata gtcaccacta 181680
ttttcatatg gcttagataa ccaggcggtt tttccttgtg gagaaccatc tagaaataac 181740
ttataaccgc ctagtttaaa atgatttaag taatgatgat attgttgatt atcccgatat 181800
aaagaataat tatttttaat atcaacataa cctacaacat cgagaaataa tttattttct 181860
gtcgccaaag agttcaataa atcaaattca tgctgtttca tatatccctc ttgcacagtt 181920
gtgattccat agctagcata gatttttaag gcatcaagga tttgtgtttt taaattttta 181980
ttttccttgc ttccttggct tgcaatcgta ataaaagctt gttcctcaag ataaccattt 182040
aaatgaccat cctcatcacg tccgtattta ccaccgacag gatcgttaat ttgatcagtt 182100
agtcctagta gctgcattgt tttagtattg actacaccca tatgacctga tgcatgagcc 182160
atcataattg gattagtggt agaaatttta tctaaatcac ttgcagtagg atggcattgt 182220
tctttgagaa aattatgatc atagccaaaa cctattaaca tttcttctga agtaggatta 182280
ttttcttcaa tataattttt aaaacattga ataatttgag caatacttgt tgctttactt 182340
aaatcaacaa gtttaagtgt acttgctaaa gaaacaacat gactatgact atcaataaaa 182400
gagggcatta aacattttcc ttgtaaatca atgaactcag tatcagcaca gactagattt 182460
tttatttcag aataattacc acatttttta atcacaccat cttctacata aatagcttca 182520
taatcactat tttccatcgt tagaatatca ccattataat atattttttt catataaacc 182580
tcctattaat attatagcca ttgcaaatga aattaatatt aagttaaaca aaaaatcagt 182640
ttaaaactga ttttataaat cttgactttc tattaaaaca caattttgat aataattaag 182700
attattttca ttaatcaaag aaatcaaatc atcattataa gtacctggct gtaaccagat 182760
atgtttgata ttaagctggt tacattcttt aatataatct attccaaatt ttggactaac 182820
aacaaacaca gcaacgtcaa ttttattttt aatggcagtt agattgggaa aagttgactt 182880
tccatcaatt tctttataaa taggtgaaac cccatacaca gttttttcta tttcatttaa 182940
acgttgataa atcttgtagc caaatttatc aggatttgtc gttacaccga ttactgcaaa 183000
attttgataa tgagttaaga tatctttagc attcataatt tcagctcctt tattttgata 183060
aatatattat atcatgataa tggcaagata tagtgataga tgcttcttta cttataaaag 183120
aagctaattt tataatacta aaaagattat ttttagatgc tatactcact aatttatatt 183180
gatagacata ctactattta ttattatata gcagtactta gcattactga atacatggac 183240
ttataagtag ggaggagtag ttgacttgaa ggatataaca gagatattaa aaggaatatt 183300
agaaggctgt gttttagaaa taattaatca agaagaaaca tatggatatg agattacaag 183360
acgactcaat cagttaggat ttacagaggt tgtggaagga acagtttata ctatattagt 183420
taggcttgaa aagagtggat tagttaagat tcaaaaaaag ttgtctaaaa tgggacctcc 183480
aagaaaattt tattctttaa atgaaagtgg acgtgaaaaa ttacgactct tttggacaaa 183540
atgggaattt atgactgata aacttaatga attaaaggag agtggtaaaa atgaataaat 183600
tttttgatga ttattttaat attaaaataa tgataaaaag taaaaaggaa tatcgaacgc 183660
atatgaaaag ggtagagcaa ttaccggctg attagcagtg tgttttaaaa aaaattcaag 183720
catatatatg gcagtttgta tccgggtcag gatatgatat gcttgaaatt caatagggtt 183780
acttgaatta tttgaagaag ggcagcagta cgaagatcag ttttagaaat aactggagat 183840
gatgttgctg attttgtaga agagctttta aaaaatacaa gaacttatcc aacggattgg 183900
aaaagtgaat ttaatcacga aattcaaaaa agcttaaaat aaaagcttct aaacaataaa 183960
cttttataat ataaagtaat tgatttgata agttaattgt ttttattaga tactttataa 184020
agtaaaaaga tgttatatct ctttattgtg atataacatc tttatttaat aattgtttat 184080
ataaggtgag atcttcttta aaagtattga ttgatgcttg ccagaatgac ttatctttta 184140
aattaatatt aacacttgaa caaacatctt ctaatgacat tttccctgtt aaggataata 184200
atttttcata agtattgcta aattttgaac cttctttttg gtaaatagtg tataatcctt 184260
tagctaaaag aagaccgaaa gcataaggaa aattataaaa agaacaatct gcataataat 184320
agtgtggttt ccaggtccac atatatggat gaagatattg atgatctaaa ccatctccat 184380
aagcatcttt ttgagcctga atcattagtt ctttgatctc ttctactgac aaagcaccag 184440
tttctctttt ttcaaaaaaa cgactttcaa ataagtatct agagtagata tcgacgatta 184500
cttgggtagc tcctgataat tcatcttcta ataagcttag tttcgtctga tcattagctt 184560
tttttaaagc agctttagtt acaattgttt cgcaaaaagt tgaagcagtc tccgcaattg 184620
gcataggata gtcactattt aaaatagatt catcatttaa acattcacca tggaagccat 184680
gacctagctc gtgagccatc gtaattgcat cagaaaagct gtcaccataa tttaataaaa 184740
aacgactttc cttgatacta tgaagattgc aacaaaaggc tccgccaact ttaccgcttt 184800
ggggataaac atcaatccaa ttattttcaa ttgctttttt cgcaaaagta cctaaatgtt 184860
cagaaaaggt actaaattga ttaataataa attggcagct tttttcgtat ggatgactgt 184920
catgatcttc gataacaggg gcataaagct caaaccaagg taatccgttt tgatatccaa 184980
gggcagtagc tttagttttt agataatccc taaagacatt aaggttttct tgcatcacag 185040
ttaataaaac atctaatgtt tcttttgaca ttcgtgcatt gataagggtt ctttctagtt 185100
cattttcata tcctcttaat ttagtagtat agagtacttc tcctttgatt ccgtttaaac 185160
aagcagcaat agcctgttct ttatcttgat aactgtttat ttctgcttgg taagcttttt 185220
tacgtatttc gcgatcctta tcataggcca tatttaaaac cgaagttaga gggtaggttt 185280
ggtcctcgat agttacttca attgatgaaa ttaattgatc ttttagtttg ctaaaagcat 185340
tactaccagt attttgcatg tgtgcaatga tgctctcact ctttttatct aaagtgtatt 185400
tttgattttg ctgaatttct tttaaaataa atagatgttc cttgattaag tttgatttta 185460
atgaatcaag cttaaaagta ctgatccatt gttgatttaa gacttcatct tcaacaaaag 185520
aagctaaaag gttatctagc tgatcgctat attttaaagc aatgctattt gttgtatcga 185580
ctgataaagt taaactaata taattagcta ctttttcaat tagttgattt aattttatta 185640
aatcgactaa ataattttct aatgattttt catcattgtt attacgatat gtatttattt 185700
gtttttgtaa tttaatgatt tggttaaaat cagtagtaaa actagaatca tcaaatgatt 185760
gatataattt cgataaatcc cattctttca ttttctatca cctcgtataa tatattttgt 185820
aaagattaca gcacctttac aatcttaatt tcatattgga ttttcctaag taataatatt 185880
ctttttcacc ttgctgcatt ctacttaatg agtctgtctt tcaattttag aatgaattac 185940
ctcatcgaat attgtttatt caatatattt tgatgcgtag ccttgattaa tattgtttta 186000
ttcttatggc gagattatga catatctaaa gaacagaggt tagtcaagta tttattttta 186060
gttatatttc aattgaaagg tgctgatttt atgaatacac tctatgtaga tattgatgaa 186120
tcaactcaaa acaatcaagt ttatgcaatg aactttaatc aggacatttt taatataact 186180
tccctaacaa tcctgataga tgtgataatc ttatcttaac tgttaagact tttgtcgata 186240
aagaaaaatt tgattctata atcatcttag ctaatctact tctatatacg actatcatat 186300
ttgggcttat ttaatagagc agctcaattg ttattatacc aaaatattga aataaattaa 186360
caaactttat gctgataatg atttaattgt tttcagcaag aaaaaaactg attagcagca 186420
atgtgcataa tttctcatca tgtaaatcaa cattggtaag ttccttgatc ttttctaaac 186480
gataaagtag tgtattgcgg tggatagcca attgttcaat tgttttatga gagtcaccaa 186540
aattacaaat atacgatttt aaagtatgat aataatcatt cttagttgat tcatcaattt 186600
gttttagttt tgtaataagt ggatggagat atatcttgta tgaactagta gtaaaaaatg 186660
attctaaagc aatatcttca aaaaaagtaa attgctgttt acttaaatcg taagctttca 186720
gtgcttgttg tttataaata ttaatatcta acagattatc gaaaatataa ctaataccaa 186780
actttaattt ataaatattt acagcagtta ttaaactttt tactttatta ataatattgt 186840
tttttgttgc tctattaagc ccggtaatta aaatatataa gcagttatct tggagataag 186900
aatatgtatt tggtaaagta ataatatgct gatgaagttg atttaaatac actatctcat 186960
tgctttttaa gcctaccttt gtagtaataa tacagtaatc tctgctaaaa ttattgggtt 187020
gtgcaggtaa taatttttct aaatcatgtt tatttatatt gtcatttgag aataagtaat 187080
tcattattgc aaaatattcg taacgattat aattatagcc ggttttgctg tgacaaataa 187140
tggatgcgat agttttagct aatttactga taaaactgaa tatttcagat gatggcttgc 187200
catctgcaaa taaaatgcat aagtaaccaa taatattatc attgtctgtt attgctgcaa 187260
taattcgtgg aattgtctgc ccaactccgt aatcgacata gataacatta ttattttgat 187320
ccaaatcttt ttgataatta cctaattgga taaatgggag catctcaact gctacttttt 187380
gatgttcttg catgtgatca aagagcatat ctccaatttg ttgatttgga tgttgtgcca 187440
aaactacata attcacatca cataagacca ttggatgatg gaaatattcg tataattgtt 187500
tcataaattg atgcagatta tgatttatta atccattgaa tagaaattca tacatatctt 187560
tcataagctc acctccttta tattataaat gtagttgtgc aatttgcaca accagtaatt 187620
aaatatttgt atttttgccc atggtatttt tttaacaaga aagataaaat ttaaatatcg 187680
acggaggtaa tttatatgaa atacgatgca ttatttacac cttttaaaat aggtaatatg 187740
gaagtgaaaa atcgttttgt tatggcacca atgggaacta attcttcaca tattgatgga 187800
tgtattgcta atgatgaaat tgattatttt gaagcgcgag ctaaaggtgg ggttggattg 187860
atcattatgg gatgtcaatt tttaaatcct gatttagcac aaggatcatt agaaggaatc 187920
ttacaaaata gttacgttat tcctcaattg acaactgtag ttgaagcgac acatcgttgg 187980
ggggcaaaaa tttgttgtca aattagttgt ggaactggaa gaaatgcttt tcctaacatg 188040
tatggagaac caccattctc ttcaagtgat acaccatcaa catttaatcc tgaaatgaag 188100
tgtcgtccat tgagtgaaga agatattaaa aaaattatga cagagtttgc taatagcgca 188160
ataattgcta aaaacgctgg ttttgatgca atagaaattc atggacatgc gggctatttg 188220
gttgatcaat tcatgtcgcc tgtatggaat aagcgaactg atgaatatgg tggtagtgct 188280
gaaaatagaa tgcgttttgc tacagaaatt gtgcaatcta taaaacaggc agttgattta 188340
ccagttatat ttagaattgc tttagatcat ctatttgtag agggtagaac cttggatgaa 188400
agtatggaat taattgagat tttagaaaaa gctggggtag atgctttaga tattgacgca 188460
ggatgttatg aacggattga ttatattttc ccaactgcat atttaggtga tgcttgtatg 188520
gattatgtat gcaaagaagc gcgcaaacat gtaaatattc cgatcatgaa tgctggaaat 188580
catacacctg aatcagcact tcgattaatt gaatctaaag atgctgattt tgttatgttt 188640
ggtcgtcaat ttattgcgga tccagataca gtaaataaat tgatgagcga tcatgaagag 188700
gatgttcgcc catgtattcg ctgcaatgaa gaatgtgtag ggagaattgt cggacgtctt 188760
actaagttga gttgtgcagt aaatcctcaa gcatgtgaag aagaacgttt tgcaattaag 188820
ccatgtagtc aagtaaaaaa tattgttgtg attggtgcag gacctgctgg attagaagct 188880
gctagagtag ctgctgctga aggacataat gtggaaattt atgaaaagac taatatgatt 188940
ggtggacaat taagtgttgc tgcgacacca aaatttaagg atcaattaaa gaaattagtt 189000
aaatggtttg aagtacaatt aaataaattg gatgtaataa tacactttaa ttatgaagta 189060
aaagcagatg atcaaatttt aaaaaatgca gatcaaatta ttgtggcctg tggagcagat 189120
gaaattatac ctccaataaa tggtatcaat aatgagaatg taattagtgt aattgacgca 189180
catatgcaca aaggtatgat taaaggtgaa aatgtcatta tgtgtggtgg gggattgtca 189240
ggtattgata gtgccattga acttgctagt gaacatggta aaaatgttac aataattgag 189300
atggctgata gtattgctaa agatgtatta tttattaacc aggcttcaat ttttgcaaag 189360
attgatgaat ataaaattaa tgtgattacc ggtgctaaag ttattgagtt taataatgat 189420
ggcattactt atcaaaaaga tgaacaagaa gttgtttgta aagcggatac gattattaga 189480
gcatttggaa tgaaaccaaa tcgtgaatta gctgaagaaa ttagaaatat ttatccaact 189540
aaaacaagaa ttgttgggga tagtgaaaaa attggtaagg ttgctaatgc tatacgtgat 189600
ggattctatg cgggaatgtc tttataaaaa tataaaagtt cgttatatta gcgaactttt 189660
tatatagctg ttttaggtat tgtctagtaa aaatttcata taattattct attttttatg 189720
aaagtataaa aatcaatctt tacttttaat tttgttgttg tgtaattttc aaagtaattt 189780
taataattgt cattgcgtga aataaagatt atataagcaa attatacata gatgatataa 189840
taatggaaaa ataaaatgaa actatgaaaa tttataaaaa atatattagg gagtttttaa 189900
aaattgaaag agtaaatatg tgattaaata aatatcatca attaatcaaa atgctttcaa 189960
atgattatga tgagattgaa gcaaggaaga tttttttaat aatattaaat ttatcattaa 190020
tttaatatta tttctttagt cataagccta ttttcaagtg taattttaaa tgtaatgtag 190080
ttatgtaaaa taacgattag attttatttg atctaatcgt tatttgttat atagtcgtaa 190140
atatcttttc ttatctcatt ttccaattta taagtaaatt gaacaacatt attgtttgta 190200
ttggacatag ttgtttgaat tggttcgcca taagcgtgca ttagacctaa atagtaaaat 190260
tctttagagg cttcatcatc tttatttttt ctaataaata gatggatttt aacatgatta 190320
gttttttcac tatatatttt aactacatct tcggattcaa tcgtacgcct tggcttagaa 190380
aaacaaatta tagtattttg atctactaat ctatcctcgt atttgataga ttcgctaatg 190440
ccttcttctt tatcataatt aataaacaca ggaaaagtgt tggtatgttt atcgtactta 190500
tatccaccta tattaagtgg aactaaattt ttttcccaat ttaataagcg gcaaacatct 190560
tcataagtgt attttttata taggcatagt gaggtatctt tatatgtatt cgtataattt 190620
tgtttataac gatttattcc aaaatcgagt aattcaatta tttgtttttt aaattcttga 190680
tcagctaata acattttaaa ttgtgcagaa gtattgaggt tttcatcaat aaatatagca 190740
tctttaaatg ttgcttttga tgagccagta gcaaaatttt gacttagaat attaatgatt 190800
gtctgataag ttattttagg taaattaaga ttatagttat tcaacaaaga ttcttttaaa 190860
ttatcaagta aattagtatg tttttcaatt gcaattttaa ttgcttctaa ttcatgaatt 190920
cgttttcctg atgcaagttt ggttgagata taagtaagat attgttcttg aacagagctg 190980
aatttaacat tatattcttt ttcgtatttt gttaggaatt tatgatatga acctaaattt 191040
ttattttgaa aaattcttaa gacatcaata gattcatatt tatcaaaatc ttttaaacta 191100
ggaattttac ctagtttttg ttttaattgt tgataacttt ccttaatgat tttaatatca 191160
ctaaaatttg ctttatcaat cgattcaaaa attttctttt tagaaatcaa atcaaaatta 191220
actgttgatg cacctggaat aattaaagaa ccttcactta cgaatcttct taaagtatct 191280
ttgttatagc ttagactacc gcttaatgca ataggaatca aaaagttctt ttcataattt 191340
ccaataaaat caataataac aacatattct ttagaaggat ctttacgtag accacgtcct 191400
agctgttgaa caaaaacaat tgctgattca gttggacgta gcatgataac ttgattaact 191460
ttaggaatat caattccttc attaaatata tctactgtaa aaatataatc taagcaatta 191520
actaaatcat cactttcaag tctgttcatc gcatcacggc gttgtgcttc agtattttca 191580
ccggttaaag atatagtctt gtaaccacgg gtattgaata agttagatag ttccgttgct 191640
tcatctttac gactacaaaa aactaatccc cgaacacgat cgcctgaata tccataacga 191700
tttatttgtt ctattatatg cttaactcgg tctttggaaa caagattgtt aaaatctgtt 191760
ttatcatcca gtgattctcc attaacttga atatctgtaa taccataata atgaaaggga 191820
cataataagt catattccat tgcttgttgt agtctaattt catacgcaat gttataatca 191880
aacattttat aaatatcgaa atcatcacta cgctctggtg ttgcagacat acctaacatg 191940
aatttagggg tgaaatagtt tactaactct tggtatgaat tagctccagc acggtgaact 192000
tcatcaataa tgatataatc aaaatcattt ggattaaaca tttcacgata ttctttttta 192060
tgaattgtct ggattgtcga aaatatataa tcagcattaa tatctttatt gttacctgtg 192120
aatacaccga aactatgatt atttattatt ttttcaaatg acaacattgc tgttctagca 192180
atattttctc gatggacaac aaataacatt cttttgggat taacattttt cacatcaaaa 192240
gcacttaaaa atgttttgcc tgtaccggtt gcagaaataa gtaaagcctt atttttattt 192300
tcgtttctaa ttgattttaa tgaatctaat gcagctcgtt gcattttatt aggttttatt 192360
tcttttttta taatattagt aactgattta ataggtttaa cataattttt tttatattct 192420
tcaatccaat catttgttaa agaaatagag ttttcccatt gttgattaaa ttcttttttt 192480
atttgttcaa caatatttgt attattggtc gatgaaaact ttaagttcca ttcttggttt 192540
attgataaag cagattgggt taaatttgaa cttcctacaa taatattaaa agtattttcc 192600
tttttgaaaa tatatccttt tggatgaaaa ccagcctttt catcatcata aattctaaca 192660
tctaaatttt taaatttaag taattcttga aacgtacggg gctcattaaa tcctagatac 192720
gtggaagtaa ttatttttcc aggaatattc ttttcttcca aatctaataa agtttgtttg 192780
attgttgcaa gtcctgacat gctgataaag gcaattgata attcaaaact atcacaagag 192840
tttagttgtt gtacaagttc atgagatagt ttcatacctt gtttataatc attaaacaac 192900
aattggggtt ggtatgtttt atcaactgta tttagcgcat ttaaattttt atgataatca 192960
attgttagtg tcatgtaaaa ttcctcgttt ttttaatgta tcaaatattt gtatgtcggc 193020
gggaatccaa ttaatatttt gttcatctaa tgaaatccat cttatactgt tatggtcatt 193080
tagtttaata tgattatctt ttaaagtaca taaatagcaa tccatatcta agataaatgt 193140
tggatattta taattcacat tcataaaaaa ttcttcaata ataattgttg tttctagttc 193200
ttcttgaatt tctctaataa gagcttgttc tccagattct ccaggttcaa tttttcctcc 193260
aggaaattca aacatgccag caaactcccc tttttttcta ctggcaatta gtattttgtt 193320
atcttttttt ataatcgcag ctactacttt tactgttttc atttaattca cactcctaga 193380
agctattata tcaacaatag gattttattt aaagaaaaga gatataaaat attaatatgt 193440
gtactttctt tatatttaga tagtgtataa taaagcatac ttattaatgt tatcattaca 193500
taaactaatg ataaaataca tgttttcatt attgtaacct ttttgttcca gtgatttaaa 193560
aaagtctact atttctaata atgaaaaatc tttattaata ttaaatatac taaaaacaat 193620
atttgtgtgg tgatttgtat aaggaatttt atcaataagt tcgttatatg tgttccaatt 193680
tttataaaca ccatcaaatt cccatatttt attacctaaa ctttttaaca gctcttcatc 193740
gagttccata atttcattat caggaaaagt ttttaataaa tgatatatgt tattacaatt 193800
tttattaaaa aatagtgttg caatagagtt gttacgtttt aacgtaatag tatttttata 193860
caaatagttg ataaatatcc aacccgtaaa gttttaattg aggaaatgca aaagatttta 193920
taaataaaaa actcaaacac caaaataggt cgatgtttga gtcttaataa gattactcca 193980
tattctctaa taaattatta ataaaactat cataattata actatgaata atactttgct 194040
gtaacttagc attattaaca atttcaataa agatatcata aaggtgctca atgtcttgtt 194100
ggtcaccttg ttttattgct agtaaaaaga taatctgaac cgtatcttgt tgataccagg 194160
ttaatggttt atcgatgata gcaacagcaa ctttagtatc tttagcacat aggcgcatag 194220
gatgtggtaa tgcaaatact tcattcatat tagtttttgc taaattttca cgttccataa 194280
cacaatcaaa ataattgcta tcaacaatat tttgtttttc cattaattga cacatttgtt 194340
ttaataaaga ttctttagag tctattccat ctaaatgaat aaagaggttt ttatcaaaaa 194400
atttatttga tttcttcatt ttatttaaag aaattgatgt tagaaattta gagattgctt 194460
cgatatcttg attatttaaa gcaaagtcaa cagtaatggt aggaatatgt tcactcttta 194520
atggtattgt agaaataaca aagtcaatat tcaataattc tctttttgta taattaataa 194580
attcgttata tgaagcttta cgaacaattg ttatcttatc tttaaagaaa acatttaatc 194640
tagcttctaa cattcttgtt gtagcttgac cagaaccaca gactaaaata acacttttgt 194700
tttgaaggct tcctgaaaaa caacgctcaa tcgcagctcc gatatgcaaa gaaacataac 194760
caacttcatc ttcagttaaa atatagggtg gcttattaaa gatttttgcg gtacacgtta 194820
aagtaatatc aaatgctaaa ggaaaattag ttttaatggt atttaataat ggatttcgtt 194880
tatttaacgc aaatgattta gtatttaaga tagatttaaa atgtaaaaag aggtcatgtg 194940
acaaaatttc atcattacgc aaatcaaaat tataatcaaa atatatatta ttcaataatt 195000
cttctactaa ctccttgatt ttattatcat tatcgactaa gtcgtttaat tgtgtattgg 195060
ctactaaatg tgaataaata tatttttttt caccttcact aatcgtaata ttaaaagtat 195120
actcaatttc atttgcaata tcatcaataa aatcagtata attatcatca attttaatag 195180
tattgttcgt attgatataa cagtcaaatt gaattcttga gatcattaaa gcaaaatgga 195240
tgattaggtt tttaaaatta aaatcatttg tttttatatg tgcatttttt aatttattag 195300
agataatttg tttaagaaga tctagatcaa ttccctcaaa aagagtatat tcatcttttg 195360
taaagccggt aacatagttt tgaaagttgt acgataaaac attttcaact agacatttgc 195420
gtttatcatc ttcattacca attattttga ccccgacatt agtttttgag atatattcaa 195480
gattatattt tgaaaaaata gcttttaaag ttttaatata gttttgtaac gtatttttac 195540
tcacatagat attatcagcc aaatcatcta gactcatata ttcatcacta tataataata 195600
aatttaataa atatttaatc cgatcttgag aactgtctaa ttctaaatta ctagttcttg 195660
tttgttttat tgagcataaa aaagtattat atttttcttg atcattgatc tcaatataat 195720
atccagcttt tctttttaat tttatttttg ctccattttt ttcaagaatt tcattaattg 195780
cctgaatatc actacggatc gttctatctg tgatgtttaa tagaactgat aactgacttg 195840
cagatactat attatcttgt ctgacatagt caaatatttc atttaaacga ttgtatggaa 195900
acatcattat cacgattcct tccttattat gtctatattg tatagataat tgttttttta 195960
tgcaaataaa ttatttccaa aataaaatgg aaatcttgat gtttataaag taaaagtttc 196020
cgttaataag tggaaatagc attgattgaa ataaatttag attcgagata gactatagtt 196080
gtagcaagga ggtagtaacg gaatgcttaa tgaagattat atatttttgg atgtgaaagt 196140
gacgaataaa aatcaattat tagggtttat tgcagacaaa gcccatgaat ataatatttg 196200
tgacaatcga gaaggactgc ttgaagattt aataaaacgt gaagcagaat ttccaacagg 196260
attgcaagat ggattcgcaa ttccacatgc acgtagtaac catgtcaaaa aggctgcaat 196320
tttatattta agaactgatg aagcaattga gtggggaact atggatgata aaaaagtgaa 196380
ttatttattt tcattgttag ttcctgaaca aaatgaagga aatcttcatt tacagatgat 196440
atctaaatta gctacttgtt tattagaaga tgagtttaag aatacggtaa aatcttcaac 196500
taataaatcg gcgctaaaag attatatatt aaaaaatatg gaggtagatt aaatgaaaat 196560
cgttggtatt gccgcttgtc ctgcgggatt agcacacaca cctatggcag ctaaagcctt 196620
agaaaaagca ggagctaaat taggttatga tttaaaaatg gagcagcaag gaagtatggg 196680
tcaggtcaac aagattactg aggaagaggc taaagaagca gcttttgtaa ttgtagcatc 196740
agatcaaaaa attctaggaa tggagcgttt tgaaggaaaa ccggtaatta gaattgatat 196800
tacaacttgt atcaaagctc cggaggcggt cataaaaaaa tgtgttcaag caacacaaaa 196860
ataaaaaagc aatttaactt ggcggagtca aattgcatac acaaaactat agtgagtagt 196920
gtgtactctc attataacat aaaatatgaa aagagaggta aaacgaatga aaaagttttt 196980
aaaagatgct aaaggacata taatgtcagg aattggttat atgctacctt taattattgg 197040
ggcatcacta gttgtggcta ttccaaaatt gataggggta gcgatgggaa tcaatagtct 197100
tgatgcttat gcaacaaaag atgggttctt acacatctta tatttattag agcaggtagg 197160
ttggacaggt attggcttag ttaatactgt attagctggt ttcattgcct tttcaattgc 197220
tgacaaacct gctattggag ctggtttaat tggtggggca ttagctagta atacaaaagc 197280
cggtttttta ggagctgtta ttgctgcgtt tatcgctgga tatattgtaa aatggggtaa 197340
agaacatatc aaattacctg attcaatgca gcaaatgatg ccgttagtta ttttaccatt 197400
tttagcaact ggtgccgttg ctataattat gggagttatt cttgcgactc cactagcctc 197460
aattaatgat gctttagtat cgtggttaag agatatgtgt agtggtggaa ctagccaatt 197520
gatcctttca ttagttttag gagcaatgat tgcttcagat atgggtggac caatcaataa 197580
gtcagcatgg atggctggaa atgttttaat gacagaagga atttatcaac caaatgtata 197640
tattaattgt gctatttgta ttcccccatt agcatatgca attgctactg taattaagaa 197700
aaatcgtttt tcaccaagtt ttaaagaagc cggtaaaggt aactgggtta tgggatttat 197760
tggtattacc gaaggagcga ttccttttac attagttaag gctagccgtt taattcctat 197820
taatatgatt ggtggagctt taggagcagg aatctgttgt ttacttggag caactgctga 197880
tattccgcca gttggaggaa tgtatggatt tgtttcaatc actggtggtt gggcttatct 197940
tgttggaatt attgttggag ctttatttat tgcaattgta gcaccaatgg ttgttgattt 198000
taatgatgat aaagatgaag aagagacaat atcagttgat gatattgaaa tagtaattga 198060
ataaaaaata ggaagatgaa aatcttccta ttaaattaaa ggagttaata tgaaaagaaa 198120
agtacatgtg atccctcatt cacattggga tcgagaatgg tattttacaa cttcaagatc 198180
aaaagtttat ttaatgaaag atcttaaaga cgttttagat acattagaga caaataatga 198240
ttttaaatat tttatggtcg atgctcaagg ttcattatta gaagattaca ttaaatggat 198300
gccacaagat aaacaaagaa ttaaaaaact tgtcaaagct aaaaaattaa tcattggacc 198360
ttggtatact caaagtgatc aactagtaat ttctggtgaa agtatcgttc gaaatatgta 198420
ttatggaatg aagtgttgtg aaactttcgg agagtatatg aatgtgggtt atgttcctga 198480
ttcatttgga cagtcaggta atatgcctca aatatatcgc cagtttggaa ttgaagatac 198540
tttattttgg cgaggcgtta gtgatgatat ggtcaaacat accgattata attggcgtgg 198600
tgatgatggc agtgttgttt ttactaccca aattcctttt ggttattata ttggtggaaa 198660
tatacctgaa gatgataaag caagtgatga gttttggcaa aaagaatgtt ttgaaaaagc 198720
aggtagccgt agtgctacaa aacatattta ctttcctaat ggatttgatc aggctccaat 198780
tcgtaaaaat cttcctgatt tgattaagaa aagaaatgaa aaagatcctg ataatgaata 198840
cattattagt tgtgttgaag actatattaa agatgtaaaa agtgaaaaac ctgatttaga 198900
agaagtgagt ggtgaattag taattgcaaa gcatatgcgg attcataaat cgattttttc 198960
atcacgaagt gatttgaaag tgttaaatac gcaagtacaa aattatgtta ctaatatttt 199020
agaaccgatg ttaacaatgt cgtatcattt aggtaatgat tatcctcata gtgcagttag 199080
tgagatttgg aaattgttat ttgaaaatgc agctcatgat tcaattggat catgtatttc 199140
tgataacgct aatgaagatg tatatatgcg ctataaacaa gctcgggata ttgcggttaa 199200
tttagttgag ttacattcac gtttgattgc aactaaaatc aagaataaaa ctaataatga 199260
gatcacctta acattattta atacattacc aaaaaaacgt aatgatacaa ttatttttga 199320
aacatattta ccagctgata attttgcaat taaggataat catggtaatc atgttaaata 199380
tactgtaatt gaaaaaacag atcttactga ctatgtttta tcacaaacaa ttcgattaaa 199440
tcctagtaaa aatatctatc tgcctagtgt agtctatcaa gcaaagattg ccatcgaagc 199500
tagagatgta ccagcattag gttatgtgca atatacaatt gatttggatg ataaatctaa 199560
tgacgatctt caagaaataa caagcatgga aaatgagtat tatcaaatta cagttaataa 199620
gcaaggaagt cttgatatct atgataaact agctgattat cattatcaaa atcaagctgt 199680
tcttgttgaa aatggtgatg atggtgacag cttcaattac tcgccgccac gtcaggattt 199740
agaaatattt tctattaaca gtgaatttga ttaccagata actggctcta gtctttatca 199800
aaagacaacg atcaattata aaatggatat tcctgctgat ttacaagaac gggctaaaca 199860
acagacaagt attaagttac cagtaacttt agaagtggtt ttaagaaaag gttcaaatat 199920
aattgatcta aacgtacatg tcgataatca aggattatca catcgtttat gcatcttatt 199980
tgatagtgcg ctgacgacta aattcaatta tgctgatcag cagtttggtt tgatcaaacg 200040
accaaacact tatgataaag aaatggagtt atatcttgaa gggttaggaa accaggagaa 200100
ggcagaaaaa ccaaaagaat tagctaattg ggtcaatgat caatctactt ggcaagaacc 200160
accaatatca attgaaccaa cgcaaagcta tgttgctctt gctgataaaa atagaggaat 200220
tgcggttatt ccccaagggg ttcgcgaata tgaaatcatt ggtgagcaag gaaatcaaat 200280
tagattaaca ttgtttagaa catatggttt tatgggtaaa gaaaatttag tttatcgccc 200340
cggtcgagct tcaggcgaaa gaatcattgc aactccagct gcccagttat taaaagaaat 200400
ggattttaaa ttaggattta caacttttaa ctgtgatatt aataatgcta atattgatac 200460
tttagccaaa gaatataaca ccccaattga agtatatgaa tacgcagact ttttaaatgg 200520
cagattgatt tttgcccaag aagatgagga acaaatttta ccagttacta attcattatt 200580
tgaaagtgaa aataacttag ttgttagtgc aatcaaaaaa agtgaagatg gtgaaggata 200640
tataattcgt ctatttaatg gtaaagatca tcaggatatt ggtgataaac taacttttaa 200700
ttttgatata agtgaagcat attatactaa tttaaaggaa gagaagattg agcaaataga 200760
tgttgttgat aatagtgtag taattaaatc aatatcacat tgtaaattta ttacgatatt 200820
aataaaataa ttataataaa cctatataga aaattacaat cattatgatt gtaattctaa 200880
taggtttttt tattataatc acatattttt tattagagca atgattaaaa gtaatagtag 200940
gtagttgatt tttaaggggc taagttaata tatttttaaa tataaaatgg taaaagtatt 201000
gatatatatt tttttattaa gatatgaaaa ggggaaaagt gcgtaagtga gaataaaatt 201060
aatcaaaaaa taaaaatgta aatatagata ctataaatat tagtattaat cctaaaaaag 201120
acgcctattt aatatagtat taaacataat taaaaaatat ttttactaga aaataataac 201180
agttaatttt tgttgttatt aatgtaagcg cttttgctta tgagataaat atatattata 201240
ataaaaatat gtaaaaaaat ggagagtata gagatggatg tatatgaaat aaagataaaa 201300
ttatatttat tgaaagatat aaaaattgaa gaaacacaga cttatttagc atactttatt 201360
gatagtgtaa tggttaaaga taatatgttt ttaggtatac atgagactaa tcagtataag 201420
ttttatactt ttgatagttt gtatccttta gctaaaaatg gggtttatca aaaagataat 201480
tcgtatatgt ttagaataag aacgttagat tatcaattag ctcaatattt atatgatact 201540
ttagctaaaa atcggactaa agaatttcaa ggtctgaccg ctgaggttaa aataattaaa 201600
ccaaaattaa tcaaaaaaat atatacactt acaccagtga ttttaaaaac agagcaggga 201660
tactggaaaa acagcattaa aacagaggat tttgaaaaac gattaaaaac taatttaatt 201720
aaaaaataca aagatataac tggtgaagaa attaatgaag attttcaatt atattatcaa 201780
attaatttta aaaataaggt tccggtatcg agaaaatata aaggaattaa attattaggg 201840
gatatgattg aattagaaat tgcagaaaat gataatgctc aaaaattagc ttttttagca 201900
atcggatcag gtttgttaga aatgaacgct agaggatttg gatttgttaa ttacatatat 201960
tattgaaagg aggttatata atgcttgatg aatgtttacg aatttttaag caagagctta 202020
aagataatac aaatttagtt ttaaatacaa taattttggc tgacggggat tatgttttag 202080
tacatgatga tggtacttat gatgtagaaa aaattaaata ttcaaaaaaa gatcattgtt 202140
ttattgaaaa acctgaagat gatctatatg aaaaattatg tttttatgat tatcaaagtc 202200
aagtaataga tacccaaaaa acttttgatc ttcctcataa attaattctt tcaaataact 202260
atttatcata ttttgtaaaa aaagaaaaat tgaataataa aaagaaaatt aatgatgcaa 202320
ctgaaaaata ttttttagca ttaagtaatc ctagagctaa gtataatggt aaagatttag 202380
agatgtataa ttttgtgact caaaatatca gcgaagttga taaaagaaga ttattgcaaa 202440
ataagcagtg gttaaaacaa tatatttata atttggatgg tgttgattat aatgaaaaag 202500
attatttaaa gatttttttt gaagcagatt atcatcaata tattaatgaa ggaaaccgtt 202560
atcttttgac aaaaatattt aactgtaacg attataacac ttatgaaaat gaaacagtgt 202620
atggagtacc aaattataat atgcaattaa attctaacaa accattttta aaaaatatga 202680
caagaatgca taaagttcca tttaaacttt ccttggaaga agcattgata caaaaacagt 202740
tttttgatta tttattaaat tatgctaata aaggtaaaac aaatatctat attagtagta 202800
atgagaatga tactaaaaga atttattttt tagataacac caaaaaaata aaaaagggat 202860
ttaatgggct ttatcttaaa attaaaaaag acaaagaatt aaaaatagag tatatagata 202920
cagttactga ttataaagaa tatttaagtc ctatgtttaa ttttcgaaat gtgattggtg 202980
cttttgatga tgaatactat caagagtata ataaaagaaa tgaggtagaa aaattactta 203040
atgatgtctt gttttccaag tttttaatta ataattattt tacggatcca gatagtataa 203100
taagtattaa gggtgaaaat attgatgttt ataaaaagaa tcttattacg tgtagagaag 203160
caatttttgc ttggatacat gtaggggcag tgggaaatat taaaaatatt ttgccaaaag 203220
cagcgttaga aacaacgatt cactctataa aaatgggaca tattaaattg gctcaaagac 203280
aatttaatct ttattttgct ataaatgaat attttaataa acaggagaat ggtatgaaag 203340
atctaagaga aagtattaga acaaaaataa attcccaaca gcaaatgaaa atagaaaatg 203400
atttagaata tagttttgca gttggacaag caatagctta tcttcagtca aagagcaaag 203460
ctaagaataa aactcaagat tttattaatc aatttataac tattaagaga gatgattcta 203520
tgaaatcaaa attgaaaaat ttatacttac attataatta tgctttatct acaggtaaga 203580
cacgtttcaa tatgttgttt gggatgatta tggaatatca gagtgatcaa aaaataaatc 203640
aaaacatgtt gattgctggt tatattggag aaaacttaat ttatgaaaag ggagaaaacg 203700
aaaatggata aaagagtata tggagtgatt ggagtatcat caaaaatggc aaattggaat 203760
gctgattttt ctggctatcc tagaagtcta tctgatggaa cgatttttgg tagtgacaaa 203820
gctttaaaat atccaatgag aaaaatgtgg gacaatgaag gtaaaaaggt attatatatg 203880
aaatctatga atttttcaaa aaaaaatgat actataacat tagtaccaaa ttcattaaaa 203940
gagagatatg aaaaattatt tgctgttgat gatttaaaaa aatgtaaaga taataaggaa 204000
gtattaacta atttaatgac tgctgttgat gttaaaaact ttggagcaac atttgcagaa 204060
gctaaaaata atatttcaat tactggtgct gttcagtttg ggcagggaat taataaatat 204120
ggtgatagtg atcttgaaac aatgcaaata ctatcaccat ttagagatac aaaagatgca 204180
gaagcaaaaa attcaactat agggactaaa aaaataatca atgaagcaca ttatttctat 204240
cctttttcaa ttaatcctag tgcttataaa gaacttgtgg ctttaggagt cacagatggc 204300
tacactgaag aagattattt aaattttaaa agaacggctt tagtagcagc aacttctttt 204360
tcatcaaacg ctaaagaagg atgtcaaaat gaatttgctt tatttgtgga aactaaattg 204420
gatacatatt taccaaattt aagcgagtat attagttttg aaaaagcaga tattaataaa 204480
attaaaattg aatgtaacat gttaaatgaa ttagaagata ttttaaatat tgaaatttat 204540
tataatcctg aaacaacagt tttagaatct aatttagaaa aagctaaaat ctataatttg 204600
attactaaaa aagaggtgta gatatgcaag cacttaagtt tactttaagt ggtaaaactg 204660
ctttttttaa gcgaccggaa gtaaatacgt attattttac ttttggtaat attcatagag 204720
ttgcgctatt aggaatattt ggggcaattt taggttatca gggctataat aatacaattg 204780
aactaccaga gttttatcaa aaattaaaag atatcaaatt atctattttg cctcaaaatg 204840
aaaagggtta tttttcaaag aaaattcaat attataacaa ttcagttggt tatgcatcca 204900
aacaacaagg aggtaattta attataaaag aacaatggct ggaaaatgtt tgttgggata 204960
ttgttgtttt gttggataat gaggaggcga ataaattagc taaagctata ataaacaaaa 205020
aatgtatttt tataccctat ttaggtaaaa atgatcatcc agctaatatc actgatcctg 205080
taattgttga tttacaaaaa cgtgatattg ataaagaaac gcttgactgc ttatttcctt 205140
caggaaattt caaaaaagca gaggatgtat atgttaattt ttataaatat caagaaagtt 205200
taccaattgg attaaatgaa aaaacgggat tgtatgagta tatgacattt attcatacga 205260
acttttatgt ggataaaggt gcagtatata gttttaatga taaaaacatt gtattttatt 205320
aacccgctat taagcgggtt ttattgaagg gagaatatta tggatatcga taaatatcta 205380
gtttcgctag aaaaaataat aattaatatt gatcagtgct atggacatag agatgatgat 205440
catcaagaaa caattaatga acatattcaa ttatgcacga aatatttaaa agagatattt 205500
aaattaaaga aattggattc aattttaaaa tcttttaaca tttctttagg agaggggtta 205560
tcaaatgaag gaaaagaaat gtttaatgag ttatttttta acacaattac ctttcatgat 205620
accggaaaaa taaatccgtt ttttcaaaaa aataaaatga ataatccagt aatgaattat 205680
ttaaatccgc caaaaaattt aaaatctgat cattcgaaat tatcggcata catctattta 205740
ggaacttatt taaataaatt gaataggtta tcaaggaatg atattggatt aataaaaccg 205800
attgtttata taaatgcatt tgttatttct cgacatcatg ctaagattga tgattttaga 205860
acatatttta tggataaact tgacagtgat gatattttgg aaaaaagaat tattgaatgg 205920
atgaacgatg agaaatttat aagtcagttt actgagaaat taagtctcga ttcattgaat 205980
acagatgagt ataattatat atttgaaaag ctagagaaat atgaaatgaa tatacaaata 206040
gatctatatg cttatgttag attcttatat tcacttctgg ttttttgtga ttattatgca 206100
acaagtgaat tttatggtga taataaaaac aatgtaatgc ttaaagatgc tgattttggt 206160
gaaatcattg aactatatga taatagtgaa ttagttacta agattagaaa aaatgatatt 206220
ggtaaagaaa aaatcaatgc attaagaaca aaagtattct tagaagcgga aagaaattta 206280
ctagaaaata ttgataaaaa tattttttat ttagaagctc caaccgggag tggtaaaagt 206340
aacacagcat taaatcttag tttacgttta attgaaaatg atgatagttt aaataagata 206400
atatatgtat atccttttaa tacattagta gaacaaaatc tagcatcgtt aaataaaatt 206460
tttggtaata gtaaggctat gaataatatt gctgtcgtta attctacaac tccattaaaa 206520
aaggatgaag atgaaaactt ttcggatgaa tatcaaaaag cattattaga ccgtcaattt 206580
ctaacatatc caattattct aacgacccac gtaggtctgt ttgatacttt ctttggaaat 206640
aaccgagaat cagcgtttgg tctatgtcaa tatgcaaatt cggtaatagt tttagatgaa 206700
atccaaaatt atcgaattga aatatggaat gagatgatca tcttcttaaa agagtttgct 206760
caaattctta atctaaaaat aattatcatg tcagcaacat taccagattt agaattactt 206820
acagatgatc gtagtaattc agtttcatta ataacaaatc ctcaagaata ttttttaaat 206880
ccaattttta aagatcgagt aaaaacagat tatagtctaa taaatgtaga aaatactgaa 206940
gaagcgttat taaatcatgt tttagagatg aataagctaa agaaaaaaat aatgattgag 207000
tttattgtta gaaaaagtgc agaaaagttc tatcgtcaat taaaagagat agaattagat 207060
tgtgaagttt tatttattag tggttttgat agtgtattag aaagagaaaa aatcattagt 207120
actgttaaaa cttcaaaaca tcttatttta gtagcaaccc aggtaattga agccggtgtc 207180
gatattgata tggatatcgg ttataaagat atatctaaac ttgatagtga agaacagttt 207240
atgggaagaa taaatcgctc atgtaaagaa gatggaaaag gaatagtata tttctttaat 207300
ttaaataagg caaccaatat ttataagggg gatgaacgtg ttgcacagaa aaatttaaca 207360
ttgtttaatg atgatatgaa aaaagtattg ttaaaaaaga actttaatta ttattaccaa 207420
aaacttctta agactctagc aaatagagct aaaaagcctg aagaaaaaaa tgttcccaat 207480
ttttttagag aaagtgttgc gtgtttagat tatcaggcag taagtaaacg aatggaattg 207540
atattagata ctagagatcg agtaacgata tttttaggaa gaacggtaat taatattgat 207600
ggggaagaat ttgatggtaa agatatttgg aatcagtatg tagatttatt gaaaaataat 207660
gaaatggatt atgctaaaaa agtatatgag ttgtcagtgg ttaaaagtat gatgaattat 207720
tttatgtatc aagttattaa aaaaaatcaa tttgatttta aagagcaggt tggagatatt 207780
tattatattg aaaatggtga tgattatatt ttagatggta aattaaatac agcccttttt 207840
gaaactgagg atgagttatt tatatagagg taagaatatg gaagtaaatg gaacattaat 207900
aaactattat tttcattgtc aaaggcaatg ttatcttcat ggtaatcgac ttaatttaga 207960
ggatgaaagt gaaaatgtga agattggtaa agcattgcat gaagaaaagt ataaagatga 208020
taagaattca gagattgcaa ttgataatat taggttagat aaattaactg caaaatattt 208080
aactgaaaca aaaaagtctg atgctgattt agttgcagca aagtggcaac tattatatta 208140
tcttaaaatt ttaaagtcaa aaggaataat acgaaaagga cgaatagaag taattgaaaa 208200
gaataaacaa aataaatctt ttattgaagt ggagctaaca gaaattgaag aaaaagaatt 208260
agataaaatt gttattaaaa ttaaagaatt attagaaaat gatcaaatac caccagtttt 208320
aaatgaaaat aaatgtaaaa aatgtgcata ttatgcatat tgttatatat aggaggtgtt 208380
gtaatgaaaa gtactaaata cataactagt atgggagatt taaaacgtaa agatgattcg 208440
ctttgtttta gaaaaagtgg taagaatata tatttaccag tagaaaatat aaaagagata 208500
tattgtttaa atgaaatttc tcttaatact aaattattag attttatctc atctaaaaat 208560
ataattattc atttttttaa ctattatcag ggttatagtg gtacctttta tccaaaagat 208620
aaatatacta gtggtaaatt gttgattaaa caggttgaaa catttaataa ttatcgtatt 208680
gatattgcaa aagcaatagt taatggtatt gcaattaaca ttgatgaaac tttatatcac 208740
tattataagc atggtaaaaa tgaggttaaa gaaacaatag actggttaag aaaagaggtg 208800
ccaaaacgtt taaaaaaagc agaagatatt aaaatgatta tggcggttga aggagaaata 208860
tggcaacgtt tttatagtat gtttatatat atattacctg aagattttat aatgaacaaa 208920
agagtaaaga gaccacctga taatccaatt aatgcactaa tttcttttgg taacacttta 208980
ctttatacaa aaacaatttc agcgatatat caaactcact taaatcaaag tatttctttt 209040
ttacatgaac ctacagaaca aagattttct ttgtctttag atttaagtga agtatttaaa 209100
ccgatcattg tttttaaaac aatctttgaa ttagtcaata ctaaaagatt aacggttgag 209160
aaacattttg ataagaaaac taattattgt cttttaaatg ataaaggtag ggatatattt 209220
attgaagctt ttgaaaatag aatggaaact aaatttttac atactaaatt aaagagaaag 209280
ataacatata aaacagctat taaatatgat ggttataaat taattaaaac aatttttgaa 209340
aataaattat ttataccatt ttctataaag gataaatatt aatgaaaata aaaaatcata 209400
actatgtaat cgtctgttac gatattgggg aaaaaagagt aaataaaata tttaagatat 209460
gtaaaaaata tcttcctcat tatcaatatt ctatttttaa gggtcctatt accccttcta 209520
aattaatttt attaaaaaaa gaactaaaaa aagctataaa caaagaagaa gattgtgtaa 209580
gtattattaa attacagagt gaggattcat ttgatgaaga aattttaggg agtcaaaaag 209640
agggaaatga agatagttta attatataat ttaccaggct caatttcttt ttaatgtcct 209700
aaaactgttg ggagagtaag cgtttaagag aattttacta gcaattataa aaaagtaaaa 209760
tcatttggta aaaaagtaga aaagtattga tagatatagg ttttgaggta taatagaaag 209820
tgtaaaatgg cttatttact agggtttaat aacaacataa gatgtattga aatccctata 209880
aatgcagggg tacctactaa accaccagcg tttaataaca acataagatg tattgaaatg 209940
tttgtcaatg ttggagcaga tggtgaaggc ggcaggttta ataacaacat aagatgtatt 210000
gaaattgacc aaaagttgga aatacatctc taatcgctcc tgtttaataa caacataaga 210060
tgtattgaaa tatggaatca ataattgttg ttccatttga taattgggtt taataacaac 210120
ataagatgta ttgaaatctg agactggaac atgatttata gatttcaaca gagtttaata 210180
acaacataag atgtattgaa atgataattc ttcaatcaat gtttggtaat cattgatgtt 210240
taataacaac ataagatgta ttgaaatatg accacaaaga cacgctcgga ttagcagtat 210300
acgtttaata acaacataag atgtattgaa attatgacgg ctatgaagaa aatattactg 210360
taacaaatgt ttaataacaa cataagatgt attgaaatgg taaaggaagc aatgatgata 210420
cagtaaaact gcgtttaata acaacataag atgtattgaa ataggtaggt gtctgaacac 210480
gtccaattga caatggtgtt taataacaac ataagatgta ttgaaattgt attaacttat 210540
agttatctat agtagagtct aagtttaata acaacataag atgtattgaa atccttcacg 210600
tttattgcta gttataccat tttttccaag tttaataaca acataagatg tattgaaatt 210660
gacattagca attgggtcaa gtagggcctt tacagtttaa taacaacata agatgtattg 210720
aaatatccaa ggtgaattag gtaataatct gcttttcgcg tttaataaca acataagatg 210780
tattgaaatg cattagtttt cttaataaag ctgaccggat ccatgtttaa taacaacata 210840
agatgtattg aaataacatt tctttagcgc ttaattcttc tatcatttta gtttaataac 210900
aacgagatat taaagtgaaa aaacatgact attttgttca tattactatt aataaaatat 210960
ttttttgtta taataaaagt aaaagtaagt agaagtgggg taattatgac aaataagtat 211020
agattaaaaa taatatataa agatactaaa ttgacattag acattgagga aaatattact 211080
tttgatgaat taagctcaat tattaatgaa aaattaatgc taagtgattc gagagcttat 211140
aaatatcaaa aagatgatga tattattgtt acaagaaaaa atagtaaaaa caataaacta 211200
gcagatcttt tagaattaga tcagaagtta gtttatatta ttggtactgg taataatgtt 211260
tatagtatta atatcatcgt ttgggactac attattgaag ctgataaaaa aatattagag 211320
aagtttaatc aaatgttgaa aaatgtcaaa caagtacgtc ctgaacaagt atattattta 211380
aatagtagtc aaagaaagtt tattgacggt cttttggctg actgttatga aatgttgaaa 211440
gaaatgagtt ttagtggaat ttataattac cgcttattta aaaatggtgc tgatttttta 211500
acaacgaaag tcatctatta tattcttgat gataaatatg aaattcattt atataacaat 211560
aatgatgatt taaaggaaga taatacagaa tatttaataa ctttttatga tactaatcga 211620
gcttatttta aaggatacca aggagttaat cgtaatattt tcattcttca caaagataaa 211680
acaattaaac aaaatgattt tgaatatctt tatcacgctt taaatcgtat cattcatatg 211740
ttcaaggatg gtgatgaaga tacattattt gaaagccatg aaacatgttt atgttatgac 211800
attgcaacta ataaattttg gactgaataa taaaaaagca tcgtcttatt atactaacga 211860
taagatgatg tttttattca gaatgatctt caaaatttaa attttcatca aagaactctt 211920
taccaacaac tttcttttta tcacgggcat cttctactaa cttagaaatt aaatctttaa 211980
cttctcgagc attttttata ttctttaaat gaatttcacg ttcactgtca gctttagtgt 212040
acaaaattac tgttccagta ccaaagattt tttgtgataa atttcttcgt agacataaat 212100
cggtaatacg atacaaaagc aattcgtcat agtgagtact aaataggcca gtctcttgat 212160
ataggcgatc attttttatt tcatatttag taaaactaat tggaaaccac ataaaatgtt 212220
tacgatcttg ccaaataatt ttattttcca tcataagttc ctccaattac aacattttat 212280
ctatgatgat tataacagta aagagtagtc aattctatga ttattgaaat aatctcatta 212340
taaataaaaa aataaaacaa attatgcaaa taagtttgta tatatcgcgt aattatgcta 212400
tactcaccaa agtgtctaga aaggtataaa gaatgattga aaacaaattt aatgaattag 212460
gattaagtaa tgaagtatta aaagcaattg aagatatggg gttttctaaa ccgtcaaaaa 212520
ttcaagaaga agcaattcct gtattattga caggagttga tgtaattggt caagcacaaa 212580
ctggtaccgg taaaacttta gcatttggga gcgttttgtt gtcaaaaata actccatctc 212640
aaagaaagtt accacaagct atcattttgt caccaacaag ggaactagca atgcaaatcc 212700
atgaagaaat ggaacgtatt ggtaaatata atggaagtcg aattacttgc gtatacggtg 212760
gtagtgatat agagcgacaa attcggacca ttaaaaaagg aatcgatatt atcgtaggga 212820
caccagggcg agtaatggat ttaatgcgtc gtaatgtttt gaaactaaac gacgtaaaat 212880
tcgtagtatt agacgaagcg gatgaaatgt tgaatatggg ctttgttgaa gatatcgaaa 212940
ctattttaga aaaagttgat gatgatcgtc aaacaatttt attttcagca acaatgccag 213000
caggaattaa aaagattgct caaaattata tgcatgataa ttttgaacat gtagctgtat 213060
tatcaaaaca aacaacagct acatctgtta aacaattcta ttacgaagtg aaacaaaaag 213120
atcgttttga agcaatgtgc cgtttaattg acgtcgctaa tgttcaaaca ggaattattt 213180
tttgtagaac aaaacgtagt gttgatgaag taactgaaca aatgcagcag gcaaattata 213240
atgttgaagc gatgcatgga gatttatcac aaaatcatcg tatgaataca ttgagaaaat 213300
ttaaaaaagg aacaattaat tttttaattg caactgatgt agctgctcgt ggtattgatg 213360
ttgaaaatgt aacacatgta attaattatg aattaccaca agatattgaa tcatatgttc 213420
atcgaattgg tcgtactggt cgagctgata aagaaggaca agcttattca attattacac 213480
caagagaaaa aggattttta cgtcaaattg agcgtgtaac aaaatcttct attaccaaag 213540
cgactattcc aactctgcaa gaaatttctg aagcaaaaat tggaactctg gtaagtaaag 213600
ttgaagatca aattttggct ggtaaccata agaagttcaa gcaattggta aatgaaattg 213660
atccaacaat gttagcagac tttacggcag cattaatgta tatgacattc caagaacagt 213720
taggatatga ttataaacgt gatacgattc aggaggcttc tgaaggtaaa aggcgtgaac 213780
gtggccgtgg aaataataaa gattatacaa gaatttttat tactgctggt agtatggatc 213840
gtgtcaaagc accacaaatt gttaatttct ttgtttctaa agcaggtgtg agaaaagaag 213900
atatcggaga tattgatatc aaacgaaaat ttacatttgt tgatattaat aagaaggtaa 213960
tcaataaagt tgttgataag tgtaataagc aaaagattaa taatcgaaag attgaaatcg 214020
aaattgcaaa taaaaaataa atatttggtg aaaagattgt gttttaaaaa tacaatcttt 214080
ttttgtataa aaatatggta ttttaaaagc gcttacactt gaatgaaaag gctaacacgt 214140
gtataatata tttatgtatt aattctaagg aggattagat tgaatgaaaa aatacgttta 214200
tatgtttagc gaaggaaacg aaatgatgcg tgaccttcta ggtggtaaag gggctaactt 214260
ggctgcaatg gttaacttag ggttaccagt accacaagga tttacagtga ctactgaagc 214320
atgtaatgaa tattatgctg atggtaagat catcaatgat gaaatgaaaa aacaaattga 214380
tgactgctta gaaagattag aaaaattagc tgataaaaaa cttgggggat tagataatcc 214440
gttattagtt tcagttcgtt ctggagcaaa attttctatg cctggaatga tggatacaat 214500
tcttaactta ggtttaaatg atgaaactgt tgaagttgta gctaaacaaa caggaaatcg 214560
tcgttttgct tttgatagtt atcgtagatt tattcaaatg tactctgatg tagtttgtga 214620
agttgataaa gagttatttg aagctaaatt aagtgaatta aaaacttcaa agggatatga 214680
aagtgattta gatatcactg cagaagattt tgaaaatatc attattcctc aatataaaga 214740
aattttcaaa actcaattag gtagagactt tccacaagaa gctaaagaac aattaatggg 214800
agcaatttta gctgtattca gatcatggaa taatgatcgt gctattattt atcgtaactt 214860
aaatggaatt cctcatgatt tgggaactgc tgttaacgta caacaaatgg tatttggtaa 214920
tatgggtgat gactcaggta ctggggtatt atttactcgt aatgctgcta atggggataa 214980
tcatatttat ggtgagtatt taattaacgc tcaaggtgaa gacgttgttg ctggtattcg 215040
tacaccacaa aaaattgcta aattagaaga agatatgcca gaaatctata aacaattagt 215100
tacaattgtt aaaggattag aaaaacatta taaagatatg caagactgtg aatttacagt 215160
tgagaatggt aaactatata ttttacaaac tcgaaatggt aaacgtactg gtaaagcagc 215220
attaaaaatt gctgtagatt tagtacatga aggtttaatc aataaatatg aagcaatgac 215280
aagagttgaa cctgatcaaa tctcacaact attacatccg aactttacac ctgctgcatt 215340
agctgctgct gaagtgttga ttgaaggatt acctgcttca ccaggtgctg gtgctggtaa 215400
agtttattta actgctgaaa aagttcatga acaagctgta gctggtgaaa aagttatttt 215460
agtaagacac gaaacttctc ctgaagatat tcaaggtatg gttgattgtg aaggtatttt 215520
aacttctact ggaggaatga cgagtcatgc agctgtagtt gctcgtggta tgggtaaatg 215580
ctgtatcgta ggtgcaaaag cattatcgat tgattatgat gcaggaacat ttacaattga 215640
tggaaaaact tatccagaag gaacagaaat ttcattagat ggtacaagtg gtaaagtata 215700
tatgggaatt ttagattctg aagaatctga attaacaggt gattttgctg aattgatgtc 215760
ttgggctgat gaaatcaaga aattacaagt tcgtgctaat gctgatagcc ctcgtgatgc 215820
ggctgtagct attaaatttg gagctgaagg tattggttta tgtcgtacag aacatatgtt 215880
ctttgaagga gatcgtatcg aatatgtaag acaaatgatt ttatctgata cagtggaaga 215940
aagaattaag gcattagatg agttatataa attccaagtt gaagacttca gaggaatcta 216000
tcgtgcgatg gttggattac cggtaacagt acgtttatta gatccacctc ttcatgaatt 216060
tttaccacat actgatgaag aatatcaagc agttgctgat aaacttggaa aaacattaga 216120
agaagtgaaa actaagggcg caactttaaa agaaactaat ccaatgttag gacatcgtgg 216180
ttcacgttta gcagtaacgt atccagaaat ctataatatg caagttagag caattattga 216240
tgcagcgatt gatgttgaaa gagaattagg atgtacaatc gtaccagaaa tcatgttacc 216300
attgattggt agtgaatctg aaatcgttta tgtgaaagat aatgttacaa aagcaattga 216360
tgccgcaatt atggctaaaa atgcaaaaat tgaatataag atcggtacaa tgattgaaat 216420
tccaagagct gctttaacag ctgatgaaat tgcaaaacat gctgaatttt tctcatttgg 216480
aactaacgat ttaactcaaa tgacatttgg tttctctcgt gatgatgtag gaagtttctt 216540
gcctgaatat attaatcgta aagtaattca agttgatcca ttcgtatcgc ttgatcaaag 216600
tggtgttggt caattagtag aaatggctgc aaacaaaggt cgcagtgttc gtccaaaaat 216660
taaattaggt atttgtggtg aacatggtgg agatccagaa tcaattaaat tctgtcataa 216720
aacaggttta acttatgtat cttgttctcc atatcgtgtg ttaattgcac gtttagctgc 216780
tgctcaagct gctgctgagg aaattatcct agaacacact actgataaag tattagttgc 216840
tgataaatag ctgataaacg tctcttaatt taaagagacg tttttttatt tgtgtaaagt 216900
aggatatttg gtataataga tatggtgata aaatgaaaaa tattataatt gtagcaacag 216960
gtggaacaat tgcaggaagt ggcaaagttg gaaaagcaac taattatcag gctggaaaaa 217020
tcaatattaa ggaaataatt gactctattc caatgattaa tgaagttgct aatttaaaag 217080
caattcagct ttttaatgtc gatagtaatg agatgaatga agaacattgg ataattttag 217140
ctaataaaat aaatgatttg gcttctcaaa aaaatgttga tggtattgta gttactcatg 217200
gaactgatac attggatgag acagcctatt ttttaaatct tacaatcaat acatataagc 217260
cagtcgtttt gacaggggca atgagaccag cgagtgcaac tagtgcagat ggtccgatta 217320
atttatatca agctgtttgt ttggcttcgt gtgatgatgc tttgggacat ggcgtaatgg 217380
cagtcttttc aagtacaatt tattcagggc gagatatcca aaaaattagt aattttaaaa 217440
ctgatgcatt tgatcaaaaa gattttggat gtttgggtta tatgaatgat gataaagtta 217500
tgatgttttc aagaactttt aaaaaacata cattgcaatc agtttttagt gaaaagccaa 217560
ttactgaatt gcctccggta gggattgtct attactatgc tggtgctaaa cctgatattt 217620
tgacgatgat ggctcagaat catcgaggga ttgtgataat tggcagcggt agtggtaatt 217680
atagtcaagc atggctgaat gaaattgaaa cactaggtgc tcaaggaatc atttttgtta 217740
gagcgtctcg ggttaatcag ggaattgtat atgagagtga tgtttttgat cctcataatg 217800
tctgtatacc gtctaatact ttgtcaggac aaaaagctag agtgcttcta atgcttgctt 217860
taagtgttac tcagaataca aaagaaatta aaagaatttt taatgaatat taaagggggc 217920
acatgtacgt ggaacgaatc aaacttaatt tagatagtat tgcaatgatg ctgttttgtg 217980
ctcgattaaa agcgtataaa gaggtcccac tttctaatga ggaatggttg ttaattgagc 218040
ggattataaa aaagaagggg ttaaaaggac ctgctagttt gctgtcgatg aatcagacag 218100
aacttgaaga aattttagaa ataaatgaat ttattgctta taaaatggca cgaagaattg 218160
aaacgatgaa tatttttttt agtgttctta ataatctgga gggaaatgga attaatgtta 218220
ctacaaaata tgaagataat ttccctaaat tgttaactaa acacctaaag aaaagggctc 218280
cattatatgt gttttattgt ggtaatattg aattagttgg agaaggaatt tctttgatgg 218340
gtcttaataa ggttactaaa aaagatcgcg cctataccaa aagattggta gataaagcaa 218400
ttgaagataa tctaatttac atttccaatg atgctaaagg aattgatgat gttgctttgc 218460
attacgcact ttatcatggt tgtcattgta ttagttttgt ttgtgagcga cttggtgcta 218520
aaagcaaaga ctatactaga tatattaaat ccggacaatt agtgatgctg agtgctgagg 218580
atccaaactg ctattttgat gtaactaatg caattgagcg taatagctat gtatgtgcat 218640
tgtcaaaata tcaaattatt gtttcaagta gtattaataa tggcgcaaca tggtttactt 218700
cgttgcaaaa tttacacaat aaatggacta cacctttagc tgttgaaggg ttatatttag 218760
gaaatgatcg gttacttgat atgggagtga caccaatata tataaaagat gtattgtctg 218820
attattcgtt cgatatgatt tatgatagaa acaaaaaaat tgttgaagat gcagaagtca 218880
atattgatca gatgtcaata tttgaattta taggagaata gaatgaattt tgattataaa 218940
aaatatccag tgacagccgg ggtgattgga atatgtattt tagtttattg ttatacaacc 219000
gttaaatacg gttttgaaat gaatgcttat caaggaatca gagcaggtgg atttaatcca 219060
attttggttt tggcaggaaa tcaatattgg cgattaatta gtgcaaactt tattcatttt 219120
ggaattatgc atattttttg taactgttat tcattagtta atctaggctc agttatggaa 219180
tatttgttgg gaatgaagcg ttatttgatt attttgattg cttctgccct tgcaactacg 219240
attttaccaa cagtttttta tattttgact ggaaatggtg ctagtagtat tatgggaggt 219300
atttctggag ctatttttgg attgatggga gctttattag cattggcttg gaaatttaaa 219360
gatgtttatg catatttatt caagcaaata tcgtcaagtg ttctattgat gctgctgatt 219420
tctatattgg tgccttcgat ttctttatct ggacatattt caggtatgat tggtggtttt 219480
attgcaactt tactaattat caaatttatg cctttacgca tttggaaaaa gaaaaaaccg 219540
gaaaattatc ataatcttgt caattaataa tcagatatag taaaatataa acatatagag 219600
gagagtacaa tgaaacaaaa agtaagaaaa gcaattattc cagcggctgg attaggaaca 219660
agatttttac cagcaactaa agcactagca aaggagatgt tgccaattgt tgatacccca 219720
acaattcaat atattatcca agaagcagtg gatagtggaa ttgaagaaat tttaattatt 219780
actaattcaa ataaacatgc gatggaaaat cattttgata agtcgtatga attagaagcg 219840
cgtttaacag aatcaggtaa aatggaacaa gttaaaatga tacaagatat tgctgatatg 219900
gcaaatattt attatattcg tcaaaaagag ccaaagggat taggtcatgc ggtattatgt 219960
gcaaaatcat ttattggtga tgagccattt gcagtattat taggtgatga tattgttgta 220020
aatgatggtg gtgagccagc attaaagcaa ttaatagatg cgtatataaa taaagaagca 220080
tcagttgttg gggtacagac agttgaacat aaagatgttt gtaaatatgg aattgtcagt 220140
ccgtcacatt cgcatcctcg tgaaaatggt gggcgtttag ttaagttaaa taatatggtg 220200
gaaaagccgg cagttgaaga agctcctagc gatatggcag tattaggaag atatgttttg 220260
acaccaaaag tatttgaatt gctagaaact caaggaaaag gtgctggtgg agaaatccag 220320
ttaacagatg ctatcaaacg tttaatggat attcaagcgg tctatgcgta tgactttgaa 220380
gggattcgtt atgatgttgg tgataagttt ggttttatta aggcaacgat tgattttgca 220440
ttaaagcgcg aagatttaaa agaaaaggtt caagcatata taaattcact tgtaaaggat 220500
gttaaatgat gagttttcaa gagaaatatg aagagtataa acaaagaaaa gaagcgcaag 220560
cgttttttaa tcaaaataat gatcaaaaag tatatgggaa agattattta atagctattt 220620
tagttggatt tggttcaacg atcgttatgg gatgtatttt aacctggatt atttctaaaa 220680
taggttttaa tttttcatac tttactattt taattggaat ttttgaagct caggcaataa 220740
aaaaagtatt gaataaaagt ggtcaacaat tagccattat tgctgcagtt acttttgttt 220800
taggaattgt cgtggcacaa gcaattttta taagtataac gctacctttt tttaatgtca 220860
gcatgctagt tgaaacattc aaatattgtt tccaaaatat gataacaggt gatgtgttaa 220920
gtacaattat ctatttattt ggtgcgattg cggcatatat ggcattaaaa gattaaatat 220980
attaatttaa aagaatataa ttggctgatc ggttttagtg atcagctttt ttgttatatt 221040
atttttaata aagattgatg gattcaaggt aaatggattg ttaaataaaa acattctttt 221100
tatttaaaat gaaaaaataa tgcctttcta tatttgtgag ggtcttttag taattataac 221160
tagcaataca aaaggctacg tagtataata atggtatgca aaaggaggat ttttaaaaat 221220
ggctaaaaag tttttatcaa tggatggtaa tactgctgca gcgcacgttg cgtatgcgtt 221280
tactgaagta gcaagtattt atccaattac accttcatct ccaatggctg aaaatgcgga 221340
agcatggtct gcccaaggta aaaaaaatat ctttggttca cctgttaatg taattgaaat 221400
gcaatcagaa gccggagctg ctggtgctgt ccatggggcg ttacaaggtg gtgcacttgc 221460
aactactttt actgcgtctc aaggtttatt attgatgatt cctaacttat acaagattgc 221520
tggggaatta ttacctggtg tattccatgt atcagcaaga gcacttgcaa caagagcatt 221580
aaatattttt ggtgatcatc aagatattta tgcttgtcgc caagttggaa tgccaatgat 221640
ttgttcacac tcagttcaag aagtaatgga tttaggagga attgcacatt taacggcaat 221700
taaatcatct gttcctgtaa tgcacttctt tgatgggttt agaacatctc atgaaattca 221760
aaaagtagaa gtaatggatt atgatgtatt agaaagtctt ttagataaag aggctcttgc 221820
taaatacaag aaaaatgcaa tgaatccaca cactaaccca attgagcgcg gtggggctga 221880
aaatgatgat atttatttcc aaggtcgtga agctcaaaac aagcattatg atgcagtggt 221940
agaagtagtt gctgattata tgaaaaagat ttctgaaatt accggtagag aatatgctcc 222000
atttacatat tatggggcac ctgatgcagc aagagtaatc gttgcaatgg gatcagtaac 222060
agaaacaatt aaagaaacaa ttgatgaaat gaaccgtcgc ggtgatcgcg taggtttaat 222120
taaagtacat ctatatcgtc ctttctctgc caaatactta ttaaaagtat tacctaatac 222180
agtggaaaaa gtagctgttc tagatcgtac taaagaaatg ggtgctactg gagagccttt 222240
atatttagat gttgttagtg tccttaaaga cgttaaacat gtaagagcaa ttgttggtgg 222300
acgttatggt atgggttcta aagatactac tcctcgtcaa atcaaagcag tatatgatca 222360
tttattagag gatgctccat ttacttcatt tacaattggt attaatgatg atgtaactaa 222420
tctatcatta aaagaggatc ctgaatttaa tgttgatgct gattatacag catgtctatt 222480
ttatggttta ggttcagatg gtactgtttc agctaataaa tcttcaataa aaatcattgg 222540
ggatcatact gatttatatt cacaagctta ttttgcttat gattctaaaa aagctggagg 222600
ggcaacacgc tctaatttac gctttgggaa tactccaatc agagctactt attatgtaaa 222660
taatgcggat tttatttctt gttcattaga caactatgta attaaatatg atatgttaaa 222720
aaatcttaaa gatggtggaa cattcttatt aaatacagag ttctcaaaag aagaaattat 222780
tgattattta ccaaatcgag taaaaaaaca attagcagat aaaaaggcta aattctatat 222840
aattaatgcc aataaaattg ctggcgaaat tggtatggga agaagaacta atacaattct 222900
tcaatctgca ttctttgcat taaatcccca aatcttacca attgaaaaag ctgttgaata 222960
tatgaaagaa atggcaaaga aaacatatag taaaaaaggt gatgctattg tccaacttaa 223020
ctacaaagca attgatgcag gtaaagacgc aattgaagaa gtagctgttg ataattcttg 223080
gtctgattta acagtaactg caactagaag tactactgga gatgaacatt ttgatgaatt 223140
tgtttcagta atcaatagtt tagatggtta tgatttacct gtttctgctt tcatggataa 223200
attagatggt tcaatgaaat caggagtggc aatcaaagaa aagcgtgcaa ttgcaactga 223260
agttcctcgt tggaataaag ataactgtat tcaatgtaat aactgtgtaa tggtttgccc 223320
tcatgcaacg atcagagcgt tcttgcttga tgaagaagaa atggctaatt taccagaaaa 223380
cattggtgat gatgttttag ttccaatggg taaagatatg ggtggattag tatatcgtat 223440
ccaagtttca ccggataact gtgttggatg tggtttatgt gttactgaat gtccaggtaa 223500
gaaaggtgaa aaagctcttg aaatggttag tgtgaaagat gaattagtac atgctccatt 223560
agctgattac atgtatgcta atgttaaata tcgtgatgat aagtatccat taactacagc 223620
taaaggtgtt ggtttcatga gaccgtattt tgaagtttca ggtgcttgtg gtggatgtgg 223680
tgaaacacca tactatcgtt tggcttcaca attatttggt aaggatatga tgattgctaa 223740
tgctactgga tgtagttcaa tttatagtgg ttctactcct tctacacctt gtgcgattga 223800
tggaaatggt caaggaccag catgggctaa ctcattattc gaagataatg ctgaatttgg 223860
tttcggaatg aaattagctg aaaattataa agttgggcat ctattacgta ttattgaaga 223920
aaataaagat gcttgtgaac cggaactgaa ggctttattg gaagagtatg ttgaaatcaa 223980
tggtgatcgc gctaaagaaa gagagcttgt gcctcaaatc atgactgcgg ttaaagcttc 224040
aagcaacgaa gcaattaaag aattgttaaa tcatgaagga gatatggtaa gtaaatctca 224100
atggatcatt ggtggtgatg gatgggctta tgatatcggc tatggtggat tagatcatgt 224160
tattgcaagt aaccaaaatg ttaatatttt agtacttgat actgaagtat attctaatac 224220
aggcggacaa tcttctaaat catctcaagc tggatcaatc gccaaattta ctgctggggg 224280
taaatcagct gctaaaaaag atttagcaca aatcgctatg gcatatggac atgtttatgt 224340
tgctcaagtt gctatgggag caaatcctgt acaaacaatt aaagcattca aagaagctga 224400
agcttataat ggaccttctt taatcattgc ttactctcca tgtatggaac atggtattaa 224460
aggtggtctt gcaaatcatc aaagacaaca aaaagatgct gtatcttgtg gatacttcaa 224520
cttattgaga tatgatcctc gtcttgaaga tgcaggaaag aatcctttgc aagttgattc 224580
taaagcacca gactttgata aatttaaaga tttcttgtta tctgaaaacc gttttgcaca 224640
attgttaaag gttaatccag aacatgcgga ggcattaatg gagaaatgtt tagctgatgc 224700
taaaaaacgt cgtttaagat tagatagaat ggcataaaaa gtttaaatca gaggaaaaat 224760
cctctgattt tttcttattc gactgcaaat atagttgatt attacactgt tttttggaaa 224820
cttaataaaa aaataaaaaa aatgtataaa attctttaca agagcaaata ttagtgatag 224880
aataatcatg cactcgagat aagagtggag atcattgaaa actaaacaga attaagaaac 224940
acacgtcaat atccagaagg ataaaaaaga aaaaagagct aaacaaacga agagttgttt 225000
aaataaacaa tggagagttt gatcctggct caggatgaac gctggcggcg tgcctaatac 225060
atgcaagtcg aacgcgagca cttgtgctcg agtggcgaac gggtgagtaa tacataagta 225120
acctgcccta gacaggggga taactattgg aaacgatagc taagaccgca taggtacgga 225180
cactgcatgg tgaccgtatt aaaagtgcct caaagcactg gtagaggatg gacttatggc 225240
gcattagctg gttggcgggg taacggccca ccaaggcgac gatgcgtagc cgacctgaga 225300
gggtgaccgg ccacactggg actgagacac ggcccagact cctacgggag gcagcagtag 225360
ggaattttcg gcaatggggg aaaccctgac cgagcaacgc cgcgtgaagg aagaaggttt 225420
tcggattgta aacttctgtt ataaaggaag aacggcggct acaggaaatg gtagccgagt 225480
gacggtactt tattagaaag ccacggctaa ctacgtgcca gcagccgcgg taatacgtag 225540
gtggcaagcg ttatccggaa ttattgggcg taaagaggga gcaggcggca gcaagggtct 225600
gtggtgaaag cctgaagctt aacttcagta agccatagaa accaggcagc tagagtgcag 225660
gagaggatcg tggaattcca tgtgtagcgg tgaaatgcgt agatatatgg aggaacacca 225720
gtggcgaagg cgacgatctg gcctgcaact gacgctcagt cccgaaagcg tggggagcaa 225780
ataggattag ataccctagt agtccacgcc gtaaacgatg agtactaagt gttggatgtc 225840
aaagttcagt gctgcagtta acgcaataag tactccgcct gagtagtacg ttcgcaagaa 225900
tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga 225960
agcaacgcga agaaccttac caggtcttga catactcata aaggctccag agatggagag 226020
atagctatat gagatacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg 226080
gttaagtccc gcaacgagcg caacccttat cgttagttac catcattaag ttggggactc 226140
tagcgagact gccagtgaca agctggagga aggcggggat gacgtcaaat catcatgccc 226200
cttatgacct gggctacaca cgtgctacaa tggatggtgc agagggaagc gaagccgcga 226260
ggtgaagcaa aacccataaa accattctca gttcggattg tagtctgcaa ctcgactaca 226320
tgaagttgga atcgctagta atcgcgaatc agcatgtcgc ggtgaatacg ttctcgggcc 226380
ttgtacacac cgcccgtcac accacgagag ttgataacac ccgaagccgg tggcctaacc 226440
gcaaggaagg agctgtctaa ggtgggattg atgattgggg tgaagtcgta acaaggtatc 226500
cctacgggaa cgtggggatg gatcacctcc tttctaagga gaaacgcatg atcgaagatg 226560
atgcacaaga gaagtgatgt ttcgaagata ctgtttagtt ttgagtgata ctcaggtatg 226620
actcagagat cattgaaaac tggataatag aaaataaatt gcgatagaaa tagaaaatga 226680
gatcgaaata gtaattgtta ttattgaggt ctttctagaa aagtcgaaaa ctaagaattt 226740
tcatcactaa aaaacataaa tcgaaacgga tggatggatt ttagtaaata gttgaaaata 226800
gtaatcaagc aaacaccaaa ataggtaaag taagaaagag cgtatggcgg atgcctaggc 226860
acagagaggc gaagaaggac gcagcaaaca gcgaaatgcg acggttagca gtaagcatgc 226920
aacgatccgt cgatgtccga atgggggaac ccacctggag tagagaccag gtatcctgaa 226980
gtgaataaat agcttcagag aggcgagact cagggaactg aaacatctaa gtacctgaag 227040
gaagagaaaa taaacgaatg attccctaag tagcggcgag cgaaagggga agagcccaaa 227100
ccgatcttag gatcggggtt gtaggactgt cggcaaagag caagaaatca ttataggcga 227160
acggaatggg aagtccggcg aaacagggtg acagccccgt agccgaaata gtgaagaagc 227220
acgagacagc acctgagtac ggcgggacac gaggaatcct gtcggaatcc accaggacca 227280
tctggtaagg ctaaatactc ctctgtgacc gatagtgaac cagtaccgtg agggaaaggt 227340
gaaaagaacc ccgggagggg agtgaaatag aacctgaaac catatgctta caagaagtta 227400
gagcccgtta aagggtgata gcgtgccttt tgtagaatga accggcgagt tacgatatgg 227460
agcgaggtta agcaggatat gcggagccga agcgaaagcg agtcttaaca gggcgaaagt 227520
tgcatgtcgt agacccgaaa ccgagtgatc tagccatgac caggttgaag ttggggtaaa 227580
acccgatgga ggaccgaacc gacccccgtt gaaacgttgg cggatgagtt gtggctaggg 227640
gtgaaattcc aatcgaactc ggagatagct ggttctcccc gaaatagctt tagggctagc 227700
gtcgaggtaa agtcgtgtga aggtagagca ctgaatatgt gatggcccca tctcggggta 227760
ctgaacataa tcaaactccg aatgtcacaa agatatactc ggcagtcaga cagtgggtga 227820
taaggtccat tgtcaaaagg gaaacagccc agaccatcag ctaaggtccc aaaatatata 227880
ctaagtggaa aaggatgtgg agatgtccag acaactagga ggttggctca gaagcagcca 227940
tcctttaaag agtgcgtaac agctcactag tcgaatgact ctgcgccgat aatttaccgg 228000
ggctaagtat attaccgaag ctatggattt acgcgtaagc gtgagtggta ggggagcgtt 228060
ctatgtgcgg agaagcggta ccgtaaggag ccgtggagcg catagaagag agaatgccgg 228120
tgtgagtagc gaaacgtggg tgagaatccc acgcaccgaa aacccaaggt ttccagagga 228180
aggttcgtcc gctctgggta agtcgggacc taaggcgagg ccgagaggcg tagtcgatgg 228240
acaacaggta gagattcctg tacttacggt atgaatgatg gagtgacgga gaaggctagc 228300
ggatcctgct gatggaaatg caggtgcaag cgaggtagcc gacagccagg caaatccggc 228360
tgtcgaaagg caaaggcgtg aggcgtatgg aaagctgcgg caagtacaga agtccgtgaa 228420
gccagcttcc aagaaaagct tctagtgata atcatacagt aacccgtacc gaaaatggac 228480
acacatgggt gaggagagaa tcctaaggtg agcgagagaa ctatagctaa ggaactctgc 228540
aaaatgactc cgtaacttag ggataaggag tgctcataga gatatgagcc gcagtgaaac 228600
ggcccaagcg actgtttacc aaaaacacag ctctatgcta agtcgaaaga cgacgtatat 228660
ggggtgacgc ctgcccggtg ctggaaggtt aagaggatgt gtcagcgcaa gcgaagcatt 228720
gaattgaagc cccagtaaac ggcggccgta actataacgg tcctaaggta gcgaaattcc 228780
ttgtcaggta agttctgacc cgcacgaaag gcgtaacgat ttgggcgctg tctcagctgt 228840
agactcggtg aagtcttagt acctgtgaag atgcaggtta cccgcgacta gacggaaaga 228900
ccccatggag ctttactgta gcttgatatt ggactttgat gcaagatgta caggataggt 228960
aggagactga gagacatgca cgccagtgtg tgaggagtca atgttgggat actactcttc 229020
ttgtattgga gttctaaccg gatgccatgg aactggcaac gggacagtgt caggtgggca 229080
gtttgactgg ggcggtcgcc tcccaaagag taacggaggc gcccaaagat accctcagct 229140
tggatggaaa tcaagcgcag agtgcaaagg cataagggtg tttgactgcg agacctacaa 229200
gtcgagcagg gacgaaagtc gggcttagtg atccggcggt gctgaatgga aaggccgtcg 229260
ctcaacggat aaaagctacc ctggggataa caggctgatc tcccccaaga gttcacatcg 229320
acggggaggt ttggcacctc gatgtcggct catcgcatcc tggagctgaa gtcggttcca 229380
agggttgggc tgttcgccca ttaaagcggt acgcgagctg ggttcagaac gtcgtgagac 229440
agttcggtcc ctatctgtcg tgggcgtagg aagtttgaga agatctgtcc tcagtacgag 229500
aggaccggga tggacatatc aatggtgcac cagttgtcac gccagtggca cagctgggta 229560
gctaaatatg gaagggataa acgctgaagg catctaagtg tgaaacccac ttcaagatga 229620
gacttcccat tacgcaagta agtaagaccc cttaaagacg ataaggttga taggtcagga 229680
gtgtaagcat ggcgacatgt tcagcggact gatactaata ggtcgaggac ttaacctaga 229740
gaaaaagggt taaggcttga aactgaaaga agacaaagtg gaagacaaaa gacgcaagaa 229800
aactattatc tagttttgag tgattctcga aaggaattgc ttagaaaaga agatctggta 229860
gcgatagcat gatggacaca cctgttccca taccgaacac agaagttaag catcataacg 229920
gcgaagatag taccaaggtg cgacaatagc aagctgccgg ttcttttttt atttacggat 229980
acctctgcgt atcctttttt ctttgttcta aaccgaagta tgccttactt ataatccttt 230040
aaattaggac tactttgtag tataatagat atggtgataa aatgaaaatt aaattatatt 230100
ttggacaaga agatgctatc aaaaaatcag gaattggtcg tgcttttgtc catcaaaaaa 230160
aagcattaga attatcagga atcccttata ctacagataa ggatgatttg gattatgata 230220
ttctccacat taatactgta tggcctgata gttttaagat aataaatcaa gcacgaaagt 230280
ataataaaaa gattgtatat catgctcata gcacagaaga agattttaaa aattctttta 230340
tgttttctaa tactgtttca ggggtttata aaaaatggct gatcagtatg tatacaaaag 230400
gtgattatat tgtaactccg actccttatt caaagcggat tttagaatct tatggaatta 230460
cacttccaat taaagcagtt tcgaatggtg ttgatttgac acagtttaat cctagtcaag 230520
aacaaattga atcgtttatt cagcaataca aaattgattc taaagatgtt gttattattt 230580
cggtaggttg gctatttgaa agaaaaggat ttgatacttt tgtatcggtg gcaaagaaat 230640
tgcctgagta taaatttatg tggtttggtg atattaaatt atcacgtcct acaaaaaaga 230700
ttaaagattt actagatgat ttacctcaaa atgttatttt accaggctat gttagcggtg 230760
atataattaa aggggcttat ggaagaagta atatattctt tttcccatca agagaagaaa 230820
ctgagggaat agttgtattg gaagctttgg caagtaaatg taatgtttta ctgcgtgata 230880
ttcctgtttt ttcagattgg ttagaaaatg gcgtgaactg ttacaaaggt aaccacacag 230940
atgattttgt tgaaatcatt aaaaagatga ttaacggaga atatccttca ttagttgcgc 231000
aaggctataa agtagctaaa gagagagaac tatcaaagat agggaaagaa ttattagagg 231060
tgtatgaaga aacgctgaac ctctaatatg aggaaagctt atggataaga aatctaataa 231120
aaaatatttc cttaatatta ttttaattct tgttttaggg gcaactgtaa tttattttac 231180
aatgaaagat gatttacatg cttctttaag agcattaaca acggcctcgc ctttatggat 231240
tgttatttcc tttgcattaa tgtctatata ttttttatta gatggaatta atctatatac 231300
ttttggtaag ttatataaaa aggattatag ttataagcaa gggtttgtaa attcgatttc 231360
aggaactttt tttaatgggg ttaccccctt ttctagtggg ggtcaatttg cacaagtcta 231420
tatttttaat aagcagggaa ttgccccaac taactctgct agtattttat tgatggcttt 231480
tattgtttac cagtcagtac tagttttatt tactgcagta gtgatgattt tccgttatca 231540
ggcttatagt tcaatgtatt cagaattttt ttcattagca attttaggct tcttgattaa 231600
tttctttgtt attactggac tatttttagg tgctaaatca aagcgattac aagattttat 231660
ttgtaataat attgtaaaag cgttaagtaa aataagaatt gtaaaaaact atgaagatac 231720
ttctattaaa attgcacgtt cacttgaaaa ctttagaaca gagttaaacg tgttattaaa 231780
aaataagaat gtattgataa aatcatcatt aattaatttg tttaaattat taattatgta 231840
tagtattccc ttctttgcag caaaagcatt aaaccttaat gtttcattta tccaaatatt 231900
cgattttatt ggtatttgtt catttgttta tatgattact gcctttgttc cgattcctgg 231960
agcaagtggc gggagcgaag gagtttatta tatgttattt agccctattt taggggctgt 232020
tggtacgcca acaacattat tagtatggcg ctttgtaacc tactatttag gactaattat 232080
tggtggtatc atttttgcaa ctaatcgaga aataaataga tcggagtaaa gtaatgagaa 232140
tagcaatttt ttcagataca tatatccctg atattaatgg ggtagcgaca tcaactaaaa 232200
tattgaaaga tgaattagta aaacatggac atgatgtagt tgttgttact agcgagttac 232260
ctagtgatag tgattatatg gatgatcctc atgataatat cttaagagtt cctggattgg 232320
aaatacaagc cctgtatggt taccgggctt gtaatattta ttccttcaaa ggaatgcgtg 232380
aaattaaggg aatgaacatt gaagttatcc acgttcaaac tgaatttggg gtaggaatat 232440
ttggaagaat cgtaggagaa actcttaata ttcctgttgt ctatacgtat catacgatgt 232500
gggcagatta ttctcattat gttaatcctg taaattctgg agctattgat ggtttgatca 232560
aaaaggcaat tacacgtatt agtaaatttt atggtgataa aagtactgaa ttaatcgtac 232620
cttctttaaa gactaaagaa gcattagaat tatatggttt aaataaagac gtccatatta 232680
ttcctacagg attagaacta gaaaaatttg atcctaaaaa taaaaatact gaattgattg 232740
agcaaattaa agacaaatat ggaattaaag atcagtttat tgtaactttt ttaggacgaa 232800
ttgcgaaaga aaaaagtatt gaagtattaa ttgatgcaat gaaggaagtt attaaagaaa 232860
atgataatgt actttgcttg attgttggtg gaggaccaca gttagaggaa ttgaaagaat 232920
tagtaaaaga tgatcatatc agcaattatg tgatttttac cggccctaag cctagtaatg 232980
aggtaccaag ttattatcat ttatcaaatg tatttgtttc tgcttcaata actgaaactc 233040
aaggattgac ttatattgag gcgatggcaa gtggaatacc tgctgttgca cgctatgata 233100
aaaatttgga ggatgttatc gatgacggtg taaatgggta cttttttaaa gaaacatcgg 233160
aactagtgga aatcctacta aaattaatta atcataatta ttctaaaatg gcagaagccg 233220
catacttaag tgcaatgaag tttagtagtg aagtatttta tgaaaaggta attgctgttt 233280
atcagcaagc aattaattcg aaacactatt catatacggt caagtcgata tatccggtta 233340
aaagagggat aaatgaagtt gtttttctat ttgatgaaag tgagattatt gttgaggtaa 233400
atgataaatt aattaaagct tatcaattag agccaaataa agttattgat aaagagttat 233460
ttgatgtttt aaaagatttt gaacaagttt ctcgggccta taataaagcg ttaaaattac 233520
tcacagtaaa agattatact tataatcaaa tgaaaaagaa gttaatggat agtggtgatt 233580
atgatgatac acagttagat gcaacgctag agttacttca agagaagaat ttaatgaatg 233640
atgaagcata taccttaaat tatttaaaac gctgtacacg acttggaatt ggcttaaata 233700
aagctattta taatttacgg agttatggaa ttgatagtca aattattgat cgatgtttag 233760
aagagattga tgatgatgac gatgagtata atgctgccac cacattaatt gaatccattt 233820
atagtcgtaa tactagtttt tcttataaag caatggtgaa gaaaattcga gataaacttt 233880
atataaaagg ctttacttct gaaacaattg aacgagcact tagtgatttt gattttgagt 233940
ttgatgatca gcaagaacaa gaagctttgg aaaaagaatt ctcaagacaa aagaaaaagt 234000
attcaaaaag atatcaaggt actcatttaa aagaaaaaat cattgatact cttttaagaa 234060
aaggttacaa ttatgagcat attaaagaat tattaaatag agaaggagcc ttggatgatg 234120
aataaaataa atgaattaaa acctggtgat gaaggcgtag taattgaggc actgattaac 234180
cgtgttgttg ttggaaaaac aaatggggcc aatcgttcta cctatcttag tattacttta 234240
caagatgcta ctgggacaat cgatgctaaa ttgtggaatg caactaatga gcaagtagaa 234300
aagttagtta tgggttgtgt tgtacaagta aaaggtgatg taatcaaata taatgaagat 234360
cgccaaatga agataatcaa aattgttgtt gcttcaactg aacctcaaga acaagttaaa 234420
tttctaaaaa gtgcgccaca aacaggagaa gagcttgtaa aggagattta tacttttatt 234480
gagcgaatta acaatcttaa gttaaatcag ttagttaaag cattattcaa cgaacatgtt 234540
gaaaaattaa caatttatcc tgctgctagc aaaaatcatc atgagtatgt atctggatta 234600
gcatatcata cttgcagcat gttaaggata gctgatgctt tggctcgatt atatccatca 234660
ttaaatagag atttgttatt tgcgggaatt acattacatg atttaggtaa aacagtagaa 234720
ctaagtggtc cagttgtacc tgaatataca atcgagggta aattattggg tcatatatca 234780
atctctcagg caatgatcaa agaaatggct gataaaatga atattgaggg tgaagaagtt 234840
acgctgttac aacatataat tttatctcat catggaaaaa acgaatttgg ttcaccaata 234900
ctgccacaaa tcaaagaagc agaggtaatt tatttaattg ataatatgga tgctcggatc 234960
aatatgctag ataaagcttt agagacagta gaaccaggtg gtttttcaaa acgagttttt 235020
gctttagaaa atagagcctt ttataaacca aaaatgaatt aaattaagat tgtaaaactt 235080
attaaaaaga gtaattctat catttgacag aattactctt tttctgtgtg ccgagcatgg 235140
catacattta gctggtgaaa gtcccaccac gggtatttac cgctaagagt agtgaaccac 235200
aaaccattag tagtgatgct atgggtgatg gaattggtgt agcgaaatat tcgagattac 235260
gaaaagaaat ttgatgaggc tgaatgggag ataaggttgc agaacaaacc aagacagtaa 235320
atcaaaaacc tgtgaagata agaaaagatg tatgccttac ctcgggagac cttgtggacg 235380
atgaagtcca gtaaactgtt aaaaacagta atgataccat cgatagaaaa agatttatca 235440
caagaagtct gatgaagtca tagtagtcag aaatgatgaa ggactgaaac gtttatagag 235500
tgcaaatcac tataagcaat atttggatag ttcgaaagta aggatagcct agaactggga 235560
aacgtaatcc tagatggtaa aagtaaagag aatttgaaaa tgactatcga aaaggtcaaa 235620
caaaataaag gagtacctgg aatagacaaa atgactgtgc aagaggtgga agaagccaaa 235680
ggcaatatat agaaatctaa tgaaattaaa caaggcatgt aaatgtagat ttagtgaaga 235740
tgacatttat aagtgtgcaa acacaaggtt aggctggtat aggagaagtg gaatgaatat 235800
agtcaatttt ataatatcgc taaaagttct aagcataaag aaaggtgata gaccaggttt 235860
agtctatcac ctagattatt atcttaagag tgatataaat gtagagccgt atacgagaca 235920
tgtacgtacg gttcaatggg agaataaatt atcaaattta ttcctttacc ctattaatga 235980
aatagaagta taaataacaa tttaattatt taaatttaag aatttttacg atcactttaa 236040
aaccaattag cagtttcaga agtatgataa tgtatttgca attcggaaat gtgataactt 236100
aacacattat tattaaaaag tggttcatgt ttataaaatt cttgtatttc agtttcattt 236160
ctagatttta ttacagttat tgaagaactc atatcgcttt ttaatgacga aaagagtact 236220
ttccccgctt tcattaaaag atttgtatat ttttgatgct cttgcatcat ttcatttgtc 236280
attcgttcag gatgagtaac gataccttcg attaaaaaat acttcatagt tttaacttcc 236340
tccaaagtca ataattttaa ataaattata acatttagat taagtatcgt cattttttta 236400
acttttataa ttacagatag gataatcaat ttaaaatgat tttgataaaa aaacgctaaa 236460
taagtaatat acaagagtaa attactttaa tttagcgaaa atatctaagt tttataagct 236520
gtttatttta ttaaaaatat tatctaaatc aacttcttga ctacgatcag taaagtcgat 236580
tttgatttga tctgtttcat tatatcttgg aataatatgg atatgaaaat gcataacagt 236640
ttgaccagcc acttcatttg cattggtaag cacattcgcg ccttttgcgt ctaaattagt 236700
gattatttgg ttagtaagct tttttgttac tttgattaga tggctcaaaa cttctttatc 236760
aacatctaaa atattttgat agtgtgtttt aggaacaact aatgtatgtc cgttagttgt 236820
ttgactcaaa tctaaaaaag ctagacataa atcatcttca tatacaattt taccaggtat 236880
ttctttatta gcgattttac aaaagataca attctccatt tctataagtc ctccataata 236940
ttattctaac atagaaaaaa gataagggga aaccccttat ccgaaataat cttcatttga 237000
ttctttaatt tcatctttga ttgctgattc gtatacatca aaattgtatt tctttaaata 237060
atatgtttcc atttttgtag acatatcact aacagaagct aaattagtaa taatttcatc 237120
ttttagatct tttttatctg tattgtaaac ataaactaca gcatatttag attcagatgt 237180
cttaatcact ttattataaa taccatcttt agtaaattta tctaattttt taataatttt 237240
tgagtcgaca ctgcttgttt tagtagtgac cataccagca tcagtaccat tgttttcagt 237300
cattaaagtg tcaaaatcac tgccatcttt aactttatca attaaactta aggcagctga 237360
ttcagtgtct aaagtaataa tttttaaata tttaactttg tattctttaa ccaggtcatc 237420
atagttatct ttaatatatt tttctttaag catggtttgt tttactccta aagttaaaac 237480
accatcgata tattcttgtt cagtttcata accatattgt ttagcatatt cttctaatga 237540
agtagttaag ttttcagtaa aacttgcaac cttttcatta attctagttt gcactgcatc 237600
cttgtctgtc agttcttgat cagcaatata agttaaagct aatgaaagaa cttcagaact 237660
tccatattct tttagtaaat aatggtaaac atcattttta ctaattttaa catcatcagc 237720
agttgcaata gtcttatctc catcttttat ttctgaagta taagtagttg cactagaaga 237780
actacatccg accaaaagag ttgcaactat tgctaaagga aatatttttt tcttcattag 237840
tttgttcctc ctcggctagt ttcgcgttct tttaaagctt catcaattac attattaatt 237900
attttttcag tatttttatc atcgtattta acattataag attgataaac aatatagctc 237960
atatacttat catatgcaat caatggagta tcaatagata aatctttttt tatttctttt 238020
tttatactat ctttatcagt actagtaact tttacaaaat aatatccatc agtacctttt 238080
atggcttcac tagtttcacc actggcaagt gctaatattt tagtttcaac atcactacca 238140
aatgtttgtg aaagaccact tgtagtatct acaataccta attttccttt attcttgtta 238200
gtgtttgtat catcagagta atctttggcg atatctccaa aacttttact tgagcttaat 238260
aaagcagtga cttcactcaa ttttgctgtt tcatcagctg ttggattttc aacatcagtc 238320
attgaaactt taataagact agcttcacgt ggacttgctt gagtgtaata atcatcgaaa 238380
acttcatcaa agttcttttc aacgtaagct aataaaaagt tgcatctttg atagactctc 238440
accatgtttt cacgatattc atcaagtgaa ttaaatccac ttgaacttaa cgctgtttgt 238500
aattgagttt cagcattatc gccatattga ttttcatagt aagtttggat ttgatcaact 238560
gtttcattag catcagtttc catatcctca tcgattggga atttttgatc cattaattgt 238620
tgaagcacgg cattaaagta tgaacttttt ccactggcag tagatattac atcgttaaaa 238680
atatcatccg caaaaatatt tttatctttt ttcccactgt ttaaagaagc aactacatat 238740
ttcccatctt ctttaactgt tttcgagctg ttttgacaac cagttaataa gaaactagtc 238800
acgactagtg ccgcagcaca tttacctaat ttcatatctt tcctccttat ctttccataa 238860
cgttacaatt atactattta tcgcatctaa tttcaataaa ttaggcaaaa acacattgcc 238920
aattgttatt ttaacataat ttataatatg taggtggtag gaggggattt gatgaataac 238980
tgtaaatgca ctaatgtaaa catctatgtc ttgtttatta ttctagttat tgtaggtatc 239040
tattgtatgt aataaaaagg aggcgattac aatggcatgc caagataatt cttttacatt 239100
gatcttagtt ttattcattt tattagtaat catttgtaat atgtgctaat taaaaaagga 239160
tgtcgccaag acatcctttt aaatataaaa aactattgca ataaaatgta agatagaagc 239220
tattgaaata aatatatgcc agattacatg gttgtagggt atttttttat ttgcataaaa 239280
gtatgctccg attgaataca ttaaaccacc gataacaatt agccagagaa aagcagcact 239340
agaattttga atgattgaag gcataaatag gatggctgtc catcccataa ctagatagat 239400
agttagcgaa agctttggta aactttttat tgaaatagat ttatataaaa ttcctactat 239460
taccattgcc cattgaataa caaggatgat gattccctga tatcctttaa ttaaacacag 239520
agcaactggg gtataacttc cagcgattgc aaaatatata aagatatgat caaggattct 239580
gaatacctgt ttatgaggac tgtcatgatc catagcatga tatagagttg aaacaagaaa 239640
cattaaaaaa atgcaaattg taaaaacact aactccaaaa gattggatag gaccaccttt 239700
aacatatgca tatacagcac aagctgggat tagaagtaac atgataaatg ccataattcc 239760
atgagttata caattaaata actcttcttt aaaatatggc ggaaagattc tttttatttt 239820
ttttgtaatt ttattattca ctttttccaa ttttatcacc cagtacatac tataatataa 239880
attactttta aattcaaaca aaaatgatac gctgctgcgt atcattccat aagcttttca 239940
ttttgatgat tttctttata aacttgaaaa gttattttag cacttactaa tagtggcata 240000
gcgattacca ttccccaaat accgaagaga gaagaaccag agagaatccc aaaaagtacc 240060
cacattatac tcaaatcaat tctagatgaa tagatacgtg gagtaatcac atatgacata 240120
atcgtcgatt gaatgaaaat caaaataaat aaaataacaa ttgtagtagt tcccattcct 240180
aacgaagtaa ttaatcctaa acaattcgca acgattgggc caacatatgg aataatggag 240240
ctggctcctg aaacaaaccc aagaattaac cagttaggat gaccaattgc tagatacatc 240300
agcattgttg taattgcttg agcgattgct ccaataaaga aagctttaac atattgtact 240360
aaagaagaat caatttcacg taaatagatt ggcaatgttt tatcaatacg atatgtaata 240420
ttacgaatat gactacggat atttttaaaa ttactagaca tataaattgc tagaatgatg 240480
tagattaaaa aattagtgac attgatcata acttgattta aaacatctat agttgtatct 240540
aaaacaactg aatctttaaa gaaagcattg acaatattct gaatatggcg cattaaagaa 240600
gaaatatcat aattgaaatt ttccttaaca aacacaccaa tttcaccaag tcctgagtaa 240660
aaagccggga acatttcaga gatactttca taaatcattg gtacagctaa agaaattaat 240720
aaagttaaaa tagcaaaagc agctaagtag accattgtta cggcaatgct tcgtttagta 240780
acatactttt caatataatt tatcagtgga tttaaaacaa aggcaattgt aaatccgaca 240840
ataaatggtt tagaaaccag ccagatcgct gataacaccc cataccataa atcaccagtg 240900
gcaataatta atagtaatat tactaaaacg atcatcacat ttaataaagt atgggtgatt 240960
ttttttgatg aaataatttt aaataatgct tttagaaatt ccatttttac acccccatta 241020
catataaata taccacaatt tactaataat ataaattgaa ttgaatttct attttagaaa 241080
aatcaaaaat agttaaaatg tataaagttt tataattttc atctaaaaaa agcaattgga 241140
tgttatgatt agaatattat aatagagcaa atctcttgat aattatcgat aatttggtca 241200
caatgtggtt ataatataaa ttgtgctaga ttttgattgg aaaatagtaa aaatttttgc 241260
tataatttat cattttattt gttttttgat aacttatcta gtagaattag taaggataga 241320
aaggggctta attatgtcaa ctttaaaaat agaaaatttg catgtcagta ttggagaaaa 241380
agaaatctta aaaggtatcg atcttgttgt taatactggt gaaacccatg cgattatggg 241440
gccaaatggt aatggaaaat caacattatt atcagttatc atggggcatc ctaaatatat 241500
agttactcaa ggtagtatct acatagatga tcaaaatgtt ttagaaatga gtgttgatga 241560
aagaagtagg gcaggaatct ttttaggaat gcagtatcct caagaaattc cgggtgttac 241620
aacttcagat tttttaagag ctgcattaaa tgcacatcaa gaaaaaccag tatctttatt 241680
taaatttgta aaagcactgg ataaaaatat tgctgatttg aaaatggatg agaatttagc 241740
acatcgttat ctaaatgaag gcttctctgg tggagaaaag aaacgtaatg agattctaca 241800
aatgaaatta ttacaaccta agtttgctct attagatgaa attgattcag gtttggacgt 241860
tgatgcgtta aaaatagtat cacaagcaat taacgctatg aaatcagatg attttggatg 241920
tattatggtt tctcactatg aacggttgtt tgaattggtg ccaccaagtc acgttcatgt 241980
attagttaat ggtaaaatta ttttaagtgg tggaattgaa gtagtagaaa aaattgatca 242040
agaaggctat gactgggtaa aagaattagg agttgaaatc gctactgatg aaaagaaacc 242100
gattttactt gaaagttgtg ccaataaaga aagaatgaaa gctaaataat gaaacagtta 242160
aaagagatta aaaattattt agtatttcat aatggtacaa ttgaatgtca cccagaaaat 242220
gtaggaattg ctattaatga tggtaaaatc gatgttaaag atgctgcctc attacaaatt 242280
atttatctaa ttgatcaaga aggaaaatat tgttttgacc taaagattaa aggacaactg 242340
gaattaattg agacttatga ttttaaagtt ccagcatctt tagttaaaaa cattgaagta 242400
ttgcaaaata gtaatatttt aagatataac gataatcaaa gcagtgtcaa cgggactgtt 242460
gaagtaactg aaaatgtatc ggttgagcgt gatagtaatg taagatgcgc ttatgttgag 242520
ttatcagatt caagtattga aatgaatgtt aatcatgctt tgaatggttt taacgctaat 242580
agtacggtgc gcttagcttc attagctaaa ggacaggaaa agaagcatat gacattttcg 242640
ttaacgcatt ttgcaccaca tacaaccggg attatggata attatggtgt tgttaaggat 242700
gcatctaatt tagttatcga tgggattgga acaattaaac aaggaaatca tcaatctagc 242760
agtcatcaaa caaataaaat tattgttttt gatgagaaat gtaatgccaa ggcaaatcca 242820
tatttatata ttgatgaata tgatgtaaaa gcaagtcatg gtgctagtgt cggtaagatt 242880
gatgaggatc atttgtatta tctccaatct cgtggtttaa gtaaaaaaga tgcaatgcat 242940
ttagtaactt atggatattt tattccagtc atggaattta tagataatgc tgatttaaga 243000
gagatgttta acgaaacatt aaaagaaaag gtggggattt aatgttagat gtagaaaaaa 243060
ttcgtcagga ttttcccatg ttaaatggtg ctacgatgca tggtcaacca ctgatttatt 243120
ttgataatgg cgctacaact ttaaagcctc agtgtgtaat tgatgctgta tgtaattatt 243180
tgacaaacta ttcgggtaat gcacatcgtg gtgactatga cttatcgcat gatgttgata 243240
cacagttcga aaagacacgt gatttagttg caaaattaat aaattgcgat cgaaaagaag 243300
tagtttatac atatggttca acagacgggc taaatatgat agcatttggc tatgggatga 243360
cgcatctaga tgaaggtgat gaaatacttt taaccgttgc tgagcatgcc tcaaatactt 243420
taccatggtt tgaagtctgt gatacggtgg gaagtacggt taaatatatt gatttagatg 243480
atgaaggacg tcttactgtt gttaatgttt taaaagcaat tagtgataaa acaaaaatta 243540
tttcaatagc tcaagtttca aatgttcttg gatttgatgg accaattaaa gaaatttgtc 243600
aaattgctca tgagcgcggt attatcgttt gtgttgatgg tgcgcaaagt attcctcatg 243660
aaaaggttga cgtccaaaca ttagatattg attttctagt tttttctgga cataaaatgt 243720
gcggaccaac tggggtggga attctttatg gtaaatatga tttattacaa gaaacaaaac 243780
caactcgttg gggtggtgga agcaatgccc gatataagag ctgtggaagg attaaattaa 243840
aaaatgcacc ggctaagttt gaggctggaa cacctaatat tgagggtgtc attggtttag 243900
gtgccgcaat tgaatattta atagaaattg ggatggacaa tattcgtgat tatgaattag 243960
aattacgtca atatgcggtt aaaaaaatgt tagaattaga taatttggaa gtttataatc 244020
caaatggtca tggagcgatt gcttttaata tcaaaggtgt ttttagtcag gacggagctt 244080
cactatttaa cacatatggt attgcaataa gagctgggca acattgtgct aagattcttg 244140
atgaattttt agatgttagt caaactctta gagcatcatt ctatttctat aatacatttg 244200
aagaaattga cagatttatt gaggtatgta agaaaggaga tgacttttta gatgccttct 244260
ttggatagta tgatgttacg acaaataatt atggatcact atgaaaatcc acgtaatcat 244320
ggactagtag atgatgataa ttatcagtca gtaaatatgg attcagaaac ttgtattgac 244380
gatattgatg tgcaagcctt aattgaagat ggtgttatta aagatatccg ttttgatggc 244440
gaagcatgtg caatttgtac tgctagtacg tcaattatga gtgaattatt gattggtaaa 244500
acaattgatg aagctaatgt tattattgaa aattacaata atatgattta tgaaaaggat 244560
tatgaccctg aaattttgga agaagcaatt gcgtttatga atactcataa acaggctaat 244620
cgtattaagt gtgctacttt aggatggaca ggaatcaaac agatcctcga taaagaatag 244680
gaggaaacat atggcagata taaaaaatga aattcctgat caggaatatg cctatggttt 244740
taatgatggt gatgtttcag ttttcaagac tcctaaagga ataaatgaag aaattgttac 244800
tgaaatatca aaaattaaga atgaaccaga atggatgctt gaatatcgtc taaaatctta 244860
tcgctgcttt atggaaaagc ctatgccaac ttggggcgtt aatttagacc gtattgattt 244920
tgatgaatat acttattacg ttcgtcctag tgataaacaa acgaataaat gggaagaagt 244980
acctgaaaca attaaacaaa catttaataa attaggtatt cctgaagcag aacaaaagta 245040
tttatcggga gttagtactc agtatgaatc agaagttgtt tatcataaca tgttaaagga 245100
agttactgaa aaaggtgtta ttttcctaga tatcgatagt ggtttacgtg agtacccgga 245160
aatatttaga aaatattttg atactgttat tccttataat gacaataaat tttcagcttt 245220
aaatggagct gtttggtctg ggggatcttt tatttatgta ccgccaggag tgaaattaga 245280
taagccacta caatcttatt tcagaatcaa ttctgagcaa atggcacaat ttgaaagaac 245340
tttaatcatt gttgataaag gagcggatat ccactatgtt gaagggtgta ctgcaccaag 245400
ttattctcgt gattctcttc atgctggggt tgttgaaatt attgtgggtg aaggagcaaa 245460
atgccgttat acaacgattc aaaactggtc taacaacatt ttgaatttag taactcagcg 245520
agcaaaagta tttaaaaatg ggtcaatgga atgggtcgat ggaaatattg gtagtgctgt 245580
aactatgaag tatccaactt gtgtgttgat ggaagaggga gcaaaaggtt cttgtattac 245640
tattgctgta gctggtgaga atcagattat ggattcaggt tcaaagatga ttcacttagc 245700
gcctaataca tcaagtagta ttgtttctaa atcagtttct cgccgcggtg gaaaagtcaa 245760
ttaccgggga atggtacagc atggtgctaa agcttataat tcaaaaagca aggttgaatg 245820
tgatacgttg attttagatg acatttcaac tagtgataca gttccggtta attggatgcg 245880
aaataatgat tctattattg agcatgaggc gactgtctca aaaatttctg aagaacagct 245940
tttctattta atgtctcgtg gtttaacaaa aaaagaagca atggaaatga ttgtaatggg 246000
gttcattgag ccgtttgctc gcgaattacc aatggaatat gctgttgaac taaatcaatt 246060
aattaaattg gattttgggg atcagggtat tggataaaaa agtattacgg aaacaattga 246120
ttcaagcaag attagattta gatagcgaaa cttatgcatc taaatctaat tttattgttt 246180
ctaaattaaa acagcaacct gaatttattg aggcaagagc aattggaatc tatgtttctt 246240
ttagacatga agtagaaaca atcagtttga ttaaggaaat aattaataat aaaattgtct 246300
gtgttccaaa aattagtggt aaacagatgg atttttatca aattaattca atcaatgaat 246360
taaagacaag taattttgga attttagaac ctaataatag tcatcctgtt actaaagata 246420
atcttgattt actaattgta ccaatggttg gctacgatca aagtggtaat cgattaggtt 246480
atggcggtgg ttattatgac cgctatttaa gtgattattg tggtaatgta attggcttgg 246540
catttagttt ccaagaagtt gcaaatttac cagtagaacc atttgatttg ccgattaaaa 246600
agattattaa tgaaaaataa tcacggtttt gttataatgg ggaatataaa gtagggtgaa 246660
attatgtcaa gagagaaaac attagttaaa aatacgttaa ttatggcgtt ggggactttt 246720
ctgcctcgga ttattaattt attgactacg ccaattatta ctagtgcaac tactgatgcg 246780
cagtatgggc aattagattt agttacaacg acgattcttt catttattgt acctttatgt 246840
acgttgcaaa ttgaacaggc tctatttaga tttcttgttg atgctaaaag tgaaaaagaa 246900
caacggcgtg tcattactaa cggatatgta atgatttttg gacttatggt gattgctgcg 246960
attatttgtc tgtttgtgcc aatcagcatg tttgaaggca gttttaagct attgattatt 247020
ggatatatat ggattgagat tattgcaaca acttctaggt ttgttttaag ggctttttcc 247080
aaatataaag agtactctat tttggcggcg ttagttgtaa tagtcaactt tgttgttgtc 247140
tcagtttgtt tattgtggct aaagacaggg tatattgggg ttttaatagc attagtagct 247200
gctgatgtag tcggctttat ttatgtacta tgcgtatgta atatttttaa attttttaat 247260
tttaaatatt ttagtagcga atatgctctt aaaatgcttg gctatgcatt accgtttgta 247320
cctaatatgg tatcatggta tattaatcaa ttgtctgatc gatggattat ttcaattttt 247380
ctaggggcag ggccaaatgg agtttatgcc ttggctaata aaataccttc gattgttaat 247440
atcttatatc cggcctttaa tttagcttgg acagattcgg caacaaggag tgtaaatgat 247500
cctgatagtg gcaggtatta taataggatg tttcggatgt tgttttgcat tgtctcagca 247560
ggttcagttt tattagtggc tggatcaccg atcatctttg gaattttatg ccgtaataaa 247620
gaattatata gtgctttcga ttatacccca accttaattt tagctacata tttttattgc 247680
ttctcacaat tttttggaag tatttatgta gctgttaaaa gtgctaaaaa tatgtcggta 247740
acaacgacta ttgcagctat aatcaatatt atcatcaatt taggtttgat taatattatt 247800
ggagtacagg cagctgttct ttcaacattg gctgcgaatt tatttttagc gggatatcgg 247860
ttctttgatt tgaatcggcg ctatgtacgt ttaaaaataa ataaacgtct aacagtgttg 247920
acaatcgtaa tttttataat tagtatgtct ttagcatggt cgggagataa aattttatgg 247980
atattaaata ttgttattgc gcttggctac gcatacttta tttctggtga tatttttatt 248040
ggaatgttta aagctgtttt aaagaaacgt taatagtaat aatgttaaga tttaattatt 248100
tagcaaagta attaaatttt aacatttttt ttatgtcctt ttttgtatag ttaatattaa 248160
tgaattgggt tacaggagga taatatggaa gcatatcaaa aatcgtttaa agaggtccag 248220
caagcactag gagtcagtga taatggatta agtcaaaaag atgtaattaa gcgtcaaaca 248280
cgatatggaa gaaatgaaat tattggtgaa aagcgtcaaa gtgtttgggg aatcttattt 248340
gatcagttta aagatttatt agtaataatc ttgatttgtg cgggtattat ttcagctatt 248400
agcggagaat ttgaaagtac attggtcatc ttggttgtaa ttactttaaa tgcattgcta 248460
ggaacatttc aaactgtaaa agcacagaaa tctttggata gtttaaaaaa attatctatg 248520
ccaaaaataa aggtgttgcg tgaaggtaaa ttagttgaaa ttaaatcaaa cgaattgaca 248580
gtaggtgatt tggtatttat ccaggctgga gatgtaattg ctggtgatgg acgcttaaaa 248640
gaagcgaata atcttcaagt taatgaaagt gcattgacag gtgagtcaaa tagtgtcgaa 248700
aagcagttag ttgcaataaa tcatcaatgt actattggag atatgacaaa tatggttttt 248760
tcaggaagct tagttacaaa tggaacaggg caatatattg ttacaaacat tggaatgaaa 248820
acgcagttag gaaagattgc tgagatgttg aatgcaacta aacagcgtcg tacgccatta 248880
caaaagacgt tagatgaatt ttcagtaaaa ttgtcaattg gcattatttc aatctgtatt 248940
attgttttgt ttatggatgt ctttatcgca aaagaacaat tgctcgatgc tttgatgatt 249000
gcagtagcat tagctgttgc agcgattcct gaggcattag gatcaattgt gactattgtt 249060
ttgtcgattt caactcaaaa aatggctaaa gaaaatgcaa ttattaaaaa tttaaatgct 249120
gtggaaagcc ttggttgtgt ttcagtgata tgttcagata aaacaggaac attaacccaa 249180
aataaaatga cagcagtcga tatatataca aatcggatgt taatacaagc aaatcgttta 249240
aatcatcatg aatattgtca taatatctta ttaaaggctt ttgttctatg taataatgct 249300
actatttcta aagcacagag tattggtgat ccaacagaga ttgccttact ggaattatat 249360
caagattata attataaaaa cgcatatcga ttgcagacta aacgtcaaca ggaattgccg 249420
tttgattcca cacgaaagct gatgagtgtt acttcaaaga atcatctata cactaaagga 249480
gccccagatg ttttattaaa acgatgtaat cgaatattaa tagatggata taaagaaatt 249540
tttactaata aagataagca gcgtattatg gaacaaaatg atgctttggc gcgccaggga 249600
aagcgtgtat taggatttgc gtataaagag ttttatcgta atacattaga aaaaagggat 249660
gaaaatgatt tagtttttgt tggtctagta tctttaattg atcctcctcg cattgaaagc 249720
gctcaggcgg tcaaagattg cattttagca gggattaaac caatcatgat aactggtgac 249780
catgttgtaa ctgcgtgcag tattgcaaag aaaattggta tttttaagca aggtgataaa 249840
tgtttagagg gaactcagtt agataaactt actgatcagc aattgcggaa ttacttgcca 249900
catgtatctg tttatgcgcg agttgcacca gaacataaaa ttagaattgt tcaagcttgg 249960
caagcacgtg gagcaattgt tgcaatgacc ggtgatggtg ttaatgatgc tccggctttg 250020
aaacaaagtg atattggggt agcgatggga attacgggga gtgaagtttc taaggatgca 250080
gctagtatga ttctgacaga tgataacttt gcaactatcg ttaaagcaat cattactggc 250140
cgaaatgtat atacaaatat taaaaattca attatctatc ttttatctgg gaatttatcc 250200
gcaataattt gtgttttagt tacatcattt gcaattttac caactccttt tttgccggtt 250260
catttactat ttattaactt aattacagac tctttaccgg ccattgcgat tgggatggaa 250320
aaggggagtg atgaaattct aaagcaaaag ccacggggat cgggcgattc attacttaat 250380
aaagagacaa ttttacaagt gagttttgaa gggataataa tttgtatttt cacaatgtta 250440
gcttatttta ttggtttacg cagtgatgaa ttgactgctt catcaatggc atttggaaca 250500
ctttgtttgg cgcgactatt gcatggattt aactgtcgaa gtaacttgcc actatataaa 250560
attcctgtaa attattatag tgttggagct tttgtaattg gagtatcatt attaacatgg 250620
attctaattt ctcctaattt tcattcactt ttttcaatta gtgaactatc actaaaacaa 250680
ttagcaataa tttttgtttc tgcagcattt ccaagtatta ttatccaaat atataagatg 250740
gtttcttcga ggtataatta gaaacaaaac taaatataat atattggtgg tttaatgaaa 250800
aaacgatata tatttattgt aattaccatt attttagcaa ttgttattca agttcttagt 250860
gttaatatta ctcctgcatt aaagaagatt gcagacaaag aaataaatcg gttttgtcag 250920
atggtaatca acaatacccc ttttccagtt acattagacc atcaggaact gatcaagatc 250980
aatcgtaatg gtgatgaaat tgcgacaatt aattttaata cgagttatgc ttcaagtatt 251040
ggagctaaaa tggttaataa attagatgaa ttgtttgtag cgattgaaga aggaacatat 251100
aaaaaaacag ataattcttt ttatcaacgt cgatttcaaa agatgagtga cgaaggtggg 251160
gtaatcgctt ctattcccat tggagcatta acacaaaatc ctttcttagc aggtgttgga 251220
cctaaaataa aacttaaata tgaaactata tctgcgatta cttgctcagt cgaaaaagat 251280
gttaaaagct acggtgtgaa tcatgttatg gtttctttga aattggttat taaaattaag 251340
atgatggtat tattaccatt ttataacgag gagtttaata aagactatga ctatccatta 251400
gtgatggaaa ttattgaagg ggaggtgcct aattggtatc agaattagaa attttacaac 251460
gtttttatca gatctatcta gaacaagaaa gtgatttctt tagttttcaa ggtaattttt 251520
attatttatg caaggttaat aattttacta atgactatcc atactatgta aatgcattag 251580
gactaaatgg tttcatggtt gttaataact gttttaatcg tcctatctca atggactata 251640
tattgtatac ttatcaaatc gaagattatc attttgaaat gtttttacaa tattctttgc 251700
gacctttaga tattcaggtt gaagttttaa aaattaaaga aagctggtgt gcaattcttg 251760
atgaagcaaa gtgcaagatt ggtaactatg cttcaagaat cagtcatttt gaacattttg 251820
tagtgctgtc atattactat caaggtcttg gagaagccgc aattagcgtg ttaaatgaaa 251880
ttaaagaaac taagctagtt gcggggatag aacactttaa tatgatcgat aactatgaga 251940
tgctttgctg tccagctaat ttagtcatag cttcaagagt caaggattta gccagtagct 252000
ataaaaataa tttgatttca gttgaacagt tagaacagta cattcagatt agcgctctaa 252060
cagtagatga aataatttat ctctattcac gattattgtt tccaagtgaa tttatgcagc 252120
tggcaatcaa tgatgattgt aatgatgcac aaataaaaaa aacacttttg aatatgtatc 252180
aaaatataga taatcaaaaa gcgtctttag taattgcgtg gcaaatgtta aataaatata 252240
ctcgtttacc caaaattgcc tggttataaa agccaggtaa tttttaataa aataaaaaac 252300
ccacacttag tgtgagcaat ttactaatgg agcgggtgat gggaatcgaa cccacgtagt 252360
cagcttggaa ggctgaagtt ctaccattga actacacccg caattttaat gcattaatat 252420
gatagcacta tttttaaatg gtgacccgca ggcgattcga acgcctgacc ctctgattaa 252480
aagtcagatg ctctaccagc tgagctagcg ggtcattatt aatggctggg gtacctggat 252540
tcgaaccagg gagatgacag agtcaaagtc tgttgcctta ccgcttggct ataccccaat 252600
gaatggtgga ggagggcgga ttcgaaccac cgaaccaaag gaactgagtt acagtcagcc 252660
gcgtttagcc acttcgctac tcctccatca tggtgccggc taaaggactt gaaccctcaa 252720
cctactgatt acaagtcagt tgctctacca attgagctaa gccggcctat tttattttaa 252780
atggtggagg ttaacgggct cgaaccgctg accctctgct tgtaaggcag atgctctccc 252840
aactgagcta aacctccagt gccttggtgc ctaaatatat tatcatttac ttttcaatta 252900
gtcaataaaa aaaattataa taaattaatt tttttataat tagtttaata taataagcac 252960
ttcttttaca ttttggccat attttaaata tttatgcaaa tgaaaagacg atcaaagatc 253020
gtcataataa ttaatagcct ggtttaccaa gtaatttaaa catatttgct ttgtacactt 253080
caacacctgg ttgattaaat ggattaacac caagtaaata tacagacata gcacatgaca 253140
tttcaaagaa atataccatg taaccaaaac cataagcatc cattttatct aaagtaatca 253200
aaatgttagg tacattacca gtattaacat gagcatcaac agttccttca caagcttttt 253260
tatttacata gtctacagat ttacctgcta aataattaag accatctaaa tcatctttat 253320
cactaggaat agtgatatct ccagctggtt ctttaatttg catgattgtt tcataaagaa 253380
cttttgtacc ttcttggata aattgtccta aagaatgtaa atcagttgag aaagtagcac 253440
tagtaggtaa gataccttta ccttctttac cttctgattc accgtaaagt tgtttccacc 253500
attcagctac catagctagt tgtaattcgt aagttacaaa catttcagca ggatatccgg 253560
ctttgtgtaa aatctgacga gcaacaccat atttataagc atcattttga tcaagatcag 253620
cattaccgta tttttccatc gcatctttag caccttttaa cattgcatct acatcaattc 253680
cagccattgc gattgggaat aatcctactg gtgttaaaac tgaataacgg ccaccaacat 253740
catcaggaat tacaaatgtc gtatatccct cttcagtagc caaagttttt aatgcacctt 253800
tagccttatc tgttgtagca acgattcttt ctttagctcc aactttaccg tatttagttt 253860
cgcacatttc tttgaaaatt ctaaatgcga tagaagtttc tgtagttgta cctgatttag 253920
aaattacatt gatagcaaaa tccttatctt taatataatc agctacttgt ttaatataat 253980
ttgatgaaaa agtatttcct acataaatga tttcaacatc attagttgga tataatccgt 254040
tgattgcttc aattgctgca cgtgcaccta agtaagatcc cccaatacca caaactagta 254100
acacatctgt tttttctctt agactagcag ctgtttcttt aattaattca acttcagctt 254160
tatcataatt ttcaggtaat tcaacccacc caagaaaatc attaccagct ccagttttgt 254220
tgtgaatcat atcatggatt tcttttactt tgtccttgta tgattctaaa tcctcgctta 254280
atttagcttt agataaatct aatgtaatca ttttaacttt cctccgtgat tccttgttta 254340
agccattttt ccatggcaag agctaatggt ttgaaaccat taggcgtttc aacgattaat 254400
cgtctaggat tcttatagta aacacgttta ttgcgtctac gataacgatt atcaatggct 254460
ttcaagctaa gtttagcatg gttagtttcc tgatcaaaat caataacttt tactttgatt 254520
gattcaccca ccttaacaaa actatcgatg cttttaacga atttatcaga tatttcggaa 254580
atatgtatta atcctgttga attatctggt aaactggcaa aagctccata tggctggata 254640
ccagtaattt tgacatcaat gatatcaccg cgtttaatct tttggctcat ttaataatca 254700
ctccctgcgt ggatattata gcacaaaata aataaaatta tttcattttt tataaataat 254760
acaaaaatca ttgataaggc aatagattca ataaatttag tatatttttt tattaagtaa 254820
aagaatacat ttttaaggtt gttaaaatta aatttaagct aagaataaag tattacgcca 254880
tctagaacca ggaataacaa tttaaagaat gtagtagaag aatagttatt ctaaaattat 254940
gtgaaaagga aatgaatgat ttgctggtag aagtaagatg gctttactag ttttaaaaga 255000
cgattagaga attaatgaat ataaataggc tggaattatt gtccagccta tttgtgtata 255060
taagattatt ttctaaatat ctttaaatta ctgatatatt ttatttatta gtagtctaaa 255120
acaataacta gattacaatt ttgatacttg gtcacttaat cctttatgct ttagaaagat 255180
tgatataatt tgcgatatga gagtaagcat tctaagctct tcttttgtcc atattcgttt 255240
tcctgtacat tcatcaaagc caacgaaacc ggcaatcatt tcctgctcat agtacgcaca 255300
ctgtagtgta gaatgaattc cttgggcttc aaacagttgt ctttgttttt tgcttaatga 255360
cgtgacatca tgacagtaga agatagaatt ttcatcgaat actctttcat attcatccat 255420
atcatgataa gaaatatttt gtagttgttc ttttacagcg gtgatccctt cattacacca 255480
ttcatatgta ttggagcaat gttctttgtc tgtcatggtt tcgaaaatat aagcacggct 255540
tacgtcatag cgttttccag taatttcaag aatcagatta acagctgttt ttaaatcttt 255600
gttttgaaat agaatacgaa aggcgtaatc tgctaatgaa acagatgttt cactataaga 255660
ttgttgtgaa tcgatagttg cacctagtga agaatatgcg gtaatacttt gctgattaca 255720
agatttttca ttatatacga tatatgtatt cttgccttgg attttggctt ggtaaagggc 255780
tttatcagca tttgcataca attccaaaaa attatgtcca tcttttggat ataaagcgat 255840
accaatactg cttgttacct gaatcttact tttctctttg tcaaatagat gggcaaatgt 255900
tttttgtagt tcttcagctt tcttttctgc atctaagtgg ctagtaatat ttttcatgaa 255960
aataataaac tcgtcaccac caattctacc aacgacatca ctatcacgta ctttcttttt 256020
catagccgtt gccatttcac ctaataccat atctccagca atatgtccca atgtatcatt 256080
gatttgttta aaattatctg tgtcaatcat gaagagtgct cccttagagt catgatgttc 256140
aataataaag ttttttattt gattttcggt ttcagagcgg ttgtatatcc cagttaatgc 256200
atctttttct gctttatgct gtaatgtctt tattttttgt ctttcatctg taatatctag 256260
acccatacta taaaaacaag ggataccatc ccagctgtcc ctttcatcta cgtagcataa 256320
tgtcagtgtc cagatacgtt cttctttatt acgggtatag actcgtccct cgaatacaac 256380
gctctctttt gaatttctta atttatgaac aatctgcttg gctcttttta agtcctcagg 256440
atgcatatag ctttttaact cataacgttc acttttaaat tgttcttttg tataaccaat 256500
cattttaaga aaaatatcat tgcaccagag aattgaagaa taatcccttg catcaacacg 256560
taccatcgcg gcagaaatgg tttttaaaat tgcttctcgt tcttgatctt tctttgctag 256620
cttatattca gtactataag tgtcatggga aagctcaata cgagcagagt ggccatgcca 256680
attcaacata cgatccttga taataaaatt tctttttaat aaagggttat aaaactccca 256740
ttcataagtt tgatcttttt ttaaatattt atttgtacag aaaggacagg gggaacttct 256800
accttgtatg atttcataac actttttccc tattgcttgt tcagctctag taccaagcgt 256860
ttcacatgca actttattta aatatagaag ttcatatgtg tcaatatcac tgatataaac 256920
atttccggca ttttctgcca tcatccattg aaagttatct atatatacat ttttagttga 256980
aatgagtgta ttctgtgtat tgattaaatt actaatatcg ttatatgcaa ttgttattac 257040
ttcgaaagaa agtgaaatag ataatttaat ccattttatt tcatcatgtc taaaaggaat 257100
tcggattata cattcttgat gtaaatcacg atgctcttgc aactttgcta attgattttc 257160
aagaataata aaatcatctg tataaggttt gtagtatgtt tttaaatcct gccaaatcat 257220
tttaaaatct tttttttcat gcccggtcat tttataaaaa gcatcatttg cccatataaa 257280
tgagagtttt ttatcaggtt tgtgtttact aattggagtt gccagagtat ttaaatattt 257340
ttctaaaata gcattttcat taatcgacat tttctttgca gtatttttat tgttcatcat 257400
aaccacccct cctgatatat cacatttata tcacacatat cattctttta ttataacata 257460
gtaatttgaa aacgctatct tttcgttctg ctgaatagtt aatgaagtta aaatgtaata 257520
ttgaaatatc taataaaaaa tattttacaa taaatttttg ttaattttgg tagtggtcag 257580
atagtataat gatttaatag agagactaaa atttgataga agcgaaggta ttatagtaaa 257640
gttttgtttt ggtaattaag tcatagagga ttttttatga agaatgaaat attttatgaa 257700
tatgaatcat tagaacagag taggaaatag aaggatattt ttgttattaa gaacaaaaaa 257760
tcaaaacata attaaaaaga ttgacttcat tatgagtgag aaatcaatcc ttatatttaa 257820
attaaaatat tgtgtctagc tttgtaattt tagcatatat gtacgtagtt agaacatttg 257880
tcagacagat aaagaacctc agtttagtgg ggctctttat ctgtgttaca tgtccttttg 257940
catgtttgag aaatgagagt tttgggactt atactcattt cccggatata ttatatcaaa 258000
ataaaaagaa gaatgaaaaa ataatgcact attttttatc ccgtaatagc tgatatattc 258060
ttgcaaaaga aaaacagtca ttttttttat ataaaaaaaa taaaaaagtt aaacaattaa 258120
tagtgatgaa gaattaatag tgatgaagat aggatattta gtagtaatgg tctttattaa 258180
gtatcttgtt ttacaacacc gtcattacag tgtttttcat ccgacagtta gtcgattata 258240
atatagatca tccaagtgat ttttatggtt tttagttaaa atcatattat cctagtaatt 258300
ttcttaatta aagtgtatat ttatttaaaa ataatttttt tgtggtaaaa tagataagtg 258360
ctaaaggagt gaaggacaat ggaaaataca agtacaattg aagaagtaga aaaagtaatt 258420
aacaaattaa gaccgtactt aaatcgtgat ggtggtgaca tcgaattaat agattttaaa 258480
gatggcattg tttatgtgaa gatgttaggt gcctgtgcgg gttgttcaat gttagatgaa 258540
actttaaagg atggtgttga gcaaatctta atggaagaag taccaggagt tttaggagtg 258600
caaaatattt tagaaggaac tgagtattaa tttaaaacaa agttgagaca aaaaaagatt 258660
cattccatgc taaaatatta gtatctaata aattgcttgc aataatgtct tagatatatt 258720
attatgtatt tgttgtttta aggaatatta ttttttaatt tatgcaaact aagttaaggt 258780
gataatatga agaatgtaag gcaacaaaaa atgattgcca gtatcttatt agatattgga 258840
ctcgatgacg atattattga ggtaataacg tcactaacta aagaagaaat agaacaaata 258900
aataaaaaag actcttatta agaactacta gatgaagatc gatgatgtag tggcaaccct 258960
atattaaatt agaaggtgcc taactgagca agtttatact tgaacaatga gagaaggctt 259020
cctaactatg tatgctttct ctttaggaag cttttttatt tgtagaagga gaaagaaaaa 259080
tgaaagaaaa agtattattt acctctgaat cagtttcaaa agggcatcct gataaagttt 259140
gtgatcaaat tagtgatgct atccttgatg cgtgcttaaa agaagatcct aattcacgtg 259200
tggcctgtga agtttttgct actactgatc tggtagttat tggtggagaa atcacaacta 259260
ctgcagaagt taactatgag caggtagctc gagatgtttt aaaggacatt ggatatgatg 259320
atagcgataa aggaatcgat tatcggactt gcaaggttca ggtagtaatg gatttacagt 259380
ctcctgatat tgctttagga acaaatgacg aagtgggtgg ggcaggtgat caaggaatca 259440
tgtttggtta cgcctgtaaa gaaacaaaag ggtatatgcc tttgccgatt tcaattgctc 259500
atcatttggt tcgttatgca actgaaaaaa aggatactgg agaatttaag tcagcccgtc 259560
ctgatatgaa agctcaagta acgattgatt ataccgaaag tactcctaaa attgatacta 259620
ttttaatgtc gattcagcac gatcctgatt ttgatgaaac tgaattcaaa cgttatatta 259680
aagaagaaat aatggatgca gttgtaagaa aatataattt aaacactgat tataaagtgc 259740
tgatcaatcc aactggtcgc tttgttattg gaggaccgca tggtgatact ggcttaactg 259800
ggcgaaagat tattgttgat acatatggtg gggctgctcg ccatggtggt ggggctttta 259860
gtggaaagga tccatccaaa gttgaccgtt cagctgccta tatgttgcgt tatattgcta 259920
aaaatattgt tgcggcaaat ctttgtgata aattagaaat tcaggtttct tatgctattg 259980
gagttaaaga acctacttca atttttattg agacgtatgg aactgaacat gttgaccatg 260040
atataatcct aaaagcaatc agagataact ttgatttaac tccaggagga atcattaaaa 260100
cgttagattt acgtcaacca ttgtatctaa aaacagctgc ttatggacac tttggtcgtg 260160
gggataacaa tcttccatgg gaagagttag ataaagtaga aattctaaaa aaatatttat 260220
agataaaaat gctcgattta ttcgagtgtt ttttgtttat gttaaattta gggaaatttt 260280
atcaataatt tgagtgttat tttacaaata tatattgtat aatatgttta tacaaaggag 260340
gaattcttat gaaaatctca gtaagaggaa aaaacattga aatcacagag gctatcgaag 260400
caaagatttc agaaaaacta tctaaattag ataagtattt catcgtaagt gacaatgttg 260460
aagcaaaagt tttatgtcga gtttatcctt atggacaaaa acttgaagtt acgattccta 260520
ctgaatatgt acttttaaga gcagaggtcg tagatgatga tctatataat gctatggatc 260580
tagttgttga caaattagaa ggacaaatca gaaagtacaa aactagacta agtcgtaaat 260640
caaaagataa taaacttgcg ttcaacctat cttcaattga agatgttgaa tctgaagaag 260700
atgtcttggt aaaggttaag tcaattaccc ctaaaccaat ggatatggaa gaagcaatca 260760
tgcaaatgga attgattggt cattcattct tcgtttatcg tgatgttgaa agtgattcaa 260820
ttagtatcgt atatcgtcgt aatgatggtg attatggttt aattgaaact agtaattaat 260880
aattgaataa tagaaaaagc cctaaatggg cttttttatt ttacaacctt gataataatc 260940
tttagcaacc attaatttat caatatcatt taagatagtt actttacgaa ttgaccataa 261000
gggagcgact aaatctgaaa tatttccatc tccggttaat ctttcaataa caatattttc 261060
tgggatgtaa cttaattgtt tgacaactaa atcaatatat tcgtcacgac tcaggatttt 261120
aaaaggctgt tgtaaatata actgatgtaa ttttgttttt tcaatgacat aaagcatatg 261180
gatctttaag gcttgaatgt ccaactgccc aaccgccttt gctgtttcaa gcatcatttc 261240
atatgtttca ccaggtagac cattgataat atgtacacag acattaattt ttaattttcg 261300
taatttattc aagccgtcta ggaagtcttg ataattatgg ccacgattga ttagttcacc 261360
tgtttgatcg tgaatggtct gtaaacctaa ttcgacccat aaatcgcagc gattattaac 261420
ttctgctaaa taatttaaaa catcggtttc caagcagtct ggccgagttg cgatgctgat 261480
tgcaaccaca ttttttttat tgataaatgg ctcgatacaa gctttgattt tttttaatgg 261540
gccgtatgta ttagtattgg cttgaaaata agcaatatat ttacaatttg gccatttatt 261600
ttgaagaagc aaactaacat tactaaattg tatttctaat gaatcctgga tatttccggc 261660
aaaatcacct gaaccagtgc tgctacaaaa aatacagccg cccgtgcctt tagtaccgtc 261720
gcgatttgga caagtaaagc ccgcattcaa actaactttg gcaactttac tttgatattt 261780
atttttcaga taataattaa aagtatgata gcgtttatta tcatcactat atttaaataa 261840
gttcatttta tcaccattgc tattataaca taaggaggac gttatggcat tacaacttat 261900
taatattact aaattttata agtatggaaa aaagagacaa cgcgttattg atgatctaac 261960
aattaaattt ccaagtagag ggatgatagg aatcattggt caaagtggta cagggaaatc 262020
gactttgtta aacattattg cgggaattga gcgtccatgc aatggtcagg tattaattga 262080
tgggcatagg ctcaactatc aacaaattag aatgtatcaa cgtgattata ttagttatgt 262140
ttaccaattt tataatttag tcaatgcttt aacaataaaa gagaatttaa tcttaattac 262200
aaaaataaaa ggtattgatt taaagcaagt gtctggtcaa ttggaggagt attgtcgaac 262260
tttaaaagta gttgaattgt tggaaagata tcccgatgaa ctatcgggtg gtcaaaagca 262320
gcgaattgga ttggttcgag ctttcttgtg taatacacca attcttttag cagatgaacc 262380
aactggagca ttaaatgata aattaagtat tgaagtgatg agacttttaa aaaggtatgc 262440
caaggagcat ttagtgattg ttatttcgca taattctcga ttaattaaac aatatacaaa 262500
aatgattgta gatcttgata aaaaaaagaa ttattataat tttagtaatg aacgatatca 262560
taaatattca ccaataatca taaaaaagca gctaggtcga ctgctttttt attgtaaaag 262620
gcaactcaaa tatcaattta aaaagataat aatgatgttt gtatcacaaa tatttattat 262680
tctagctttt gttttattat taagtgcttt taatggtgga tggcaatatt tagaaaaaaa 262740
atttgaagaa gacccattaa aaagagttat tgaagtttca aaaaatgatt atattaataa 262800
tatctttgaa cgcaaagaaa ttaaaaaatt tgagaagaat aataaaatag caaatgttgc 262860
ttacaaatta gtatttagta atggaatttt aagcagttat gatgaagagt tagacgttga 262920
ggtatatcag atatttaaaa ctaaaaagtt agattatatt tctgggaaat atccttcaaa 262980
agagaatcaa atattaatta atcagacaac ggcaaagaag tataaattaa aaataggcga 263040
gagaattaat tttgaaatta atgatgatga atatgaattc actattagtg gaatcattaa 263100
tgatcatatt aatatagggg ttaatcttta tttagaacaa cagtatttag aagaagagtt 263160
aagtgatgat tgcctggata aaacagtttt aatatttcat agtgatcaag tagatgctgt 263220
gataaaagaa tatcaaaaag attatttgct gattaatcta cacggtgatt atattgacaa 263280
ctatcgatca atttttgata tcactagatt tgtgattttc ttatttattg taattagttt 263340
tgctatttca ttaattttaa tttcagttat tcttaaaaca atttttattg aacgaaaaag 263400
agatactagt cttttattgg ctaatggtct tggtaaaggt aaagcaatta atttattttg 263460
tcgtgaagca attttgatag gagggctgat tggaagtgcg ggagcaatct tagcaatggg 263520
cgtattaaga ttaattgagc tatttgattt aagtgattat ttatttaaca ttccaaggtt 263580
gtttgtctta ccgaaatata tttttacaaa atatgattta tatgtagtgt tgattgttat 263640
ttatataatt gcatgttatt tagcagggtt acaagctagt cttaaaataa acagaatgga 263700
tattagcata ttgttaaagg agaactaaaa tgctggaaat taaaaattta actaaaagat 263760
atgatgaaac tattattaaa aatttaaaca taatattacc aagtacggga ttgatcataa 263820
tagtaggaaa ttctggatgc ggaaaaacaa cattattaaa tctaattggt ggaatagatc 263880
aagattatga aggagaaata ttatttgatc atcaagatat tcgaaaaatt aaaaagtatt 263940
gtcgtaggca tattggtttt atttttcagg atttcaattt aattaattgg ctaaatgtca 264000
aagaaaatta tttgttagca aaatttttta ctaaaatttc atataaaaga gcagttgaag 264060
atcaagaaga aaaattagaa ctccgaaaac tgaataaaaa aagggtcaaa atcttatctg 264120
gtggacaaaa acaacgggtt gcattacttc gggcgatgat taaaaatgtt gatattttat 264180
tgtgtgatga gccaacaggt tctctagatg ataaaaatgc aaagatggtt tttgaattat 264240
tacatgcaga agctaaggaa cgacttgtca ttgttataac acacaatgag caattagctt 264300
atcaatatgc tgatcaatgc ttttctatgc aaaatggaca attgattggg aagtatcgcc 264360
gggataaaaa taatcatttt tattcgcgtt tagtcaaaca gcattcacca ttaaaattat 264420
atcaactggc attgttacaa tatcgtgcta atttgggtag aaatttaaaa atatcatctg 264480
gtattacagt agctttgatt tgtattatga ttacctttac actgagtgga tcattacaaa 264540
cccaaataaa aagacagctt gattctatat ttccaaatca actaatttcg attcagaatg 264600
tacataaaaa attacttagt tatcatgagt tactttcatt atcaaattta gatatgaatg 264660
aatttatcta tggggaacca gccgattatg aatttatggg agtatcactg caaagtgatt 264720
atgaagttga aaaaacaatt tatatcagtg atatgactaa accaataaaa agtaggaatt 264780
tggaaatagg acgtgaaaca aaaaatagta atgaaatagt tttatcaaaa acaacggcaa 264840
cacatcttaa tcctgattat caaaaattat tgaatcaaca attatatgga tattatttaa 264900
aggacgatca aattaaagga gtctcactca ctgttgttgg aatagggaaa gatgtaacta 264960
cttttgacac aatctatatt aatgaattag ctaatctcga tcatattagc caagcttttg 265020
cgattgataa gaaacaatta ttgtttcaat tagctatgat caatttaaat agcaaagcgg 265080
atcttgatga tcttttaatg gatttagaag atcagtatag tcaatttgaa tttaaagttg 265140
caggagaaaa tattaatgaa agaatagata catttatgtt acaaattcaa agagttcttt 265200
tactattttc tttattggct atagtagcag catgtttctt aattggggaa gtgttatatt 265260
tgtctgttat agaaaaaaca aaagatatcg gtatttttaa atgtatgggt gcgagtaaat 265320
tacagatcat gaatttagtt ttattagaaa gttttacttt aattagtgga gcgtttatct 265380
gctcttatgt atttttttat caattagtta atttaattaa tcagcttgtt gaaaatgagc 265440
tgcagcttga tttatcagga gtgtttattc aaattgatta tcagttagta attgctatct 265500
atttaggagc attatgtttt ggattgtgca gtagctatat tcccgccttt ttggcaggcc 265560
ggttagatcc tattaaagca ttaaaacaac caaattatta gtaataaaat ttgttgcata 265620
tcagcctttt tatgttataa tattctagta tttgaaagtc gatgaatagg actagtagta 265680
attgacgttt tttatagaga atcagtggct ggtggaaact gataaaacgg gttatgaact 265740
cacctaggag atgcagcggg gaattaagta gtcgttgtcg ttaactgcgt taaagttttg 265800
agggctaggt cttttagact tggaactaag gtggtaacgc gattaaaagt cgtccttaga 265860
taggatgatt tttttatttt aaggaggaat tataaaatgc cgtttgatca caaacaaatc 265920
gagccgaaat ggcaaaaata ttgggatgag cataaaacat ttaaaacaga ctgctacgat 265980
gatagtaaac caaaatatta ttgtgtggat atgtttccat atccgtcagg gaatggttta 266040
catgtagggc atccagaagg gtatactgca acagatattg tttcaagaat gaaaagaatg 266100
caaggataca atgttttaca tccaatggga tttgattcat ttggacttcc tgcagagcag 266160
tttgctattc aaacaggaca tcatccagct gaatttacta aaaagaatat tgaggtattt 266220
aagggacaaa ttaaatcttt aggtttctca tatgattggg atagagaaat cgcaactagt 266280
gatcctgaat attataaatg gacacaatgg atttttacaa aactttatga tgccggtctt 266340
gcttatgtag atgaaattcc tgtaaactgg tgtccagaac ttaaagctgt tttagcaaat 266400
gaagaagtta ttgatggaaa aagtgaacgt gggggatatc cggttatccg taagccgatg 266460
cggcaatggg ttttaaaaat tactgaatat gctgaaagat tgcttgaaga tttagatgat 266520
cttgattggc ctgaagcaac aaaacaaatg cagcgaaatt ggattggaaa atcagttgga 266580
gctaatgttg attttaggat tgatggaaca gataaaatat ttacagtctt tacaactcgt 266640
tgcgacactt tatttggtgc aacttattgt gttatggcac ctgagcatcc atatgtagct 266700
gaaattacta cattggaaca aaaagaagct attgaagctt ataaagaaag ttgtgcaagt 266760
aaatcagatt tagaaagaac tgaactaaac aaagataaaa caggtgtttt tacaggagcg 266820
tatgcaatta atcctgttaa tggtaagaaa attcctatct ggatttctga ttatgtacta 266880
gcaagttatg gaactggtgc aattatggca gtaccagcac atgatgatcg cgattgggaa 266940
tttgctaaaa agtttggaat tgagatcata cctgttttag aaggcggaaa tattgaagaa 267000
gccgcttata ctgaagatgg attacatatt aattctcaat ggttagatgg actaggaaaa 267060
caagaagcga ttgataagat gattgcctgg ttagaagagc ataagtgtgg agaaaagaaa 267120
atttcttata agttaagaga ctggttattt tctcgtcaac gttattgggg tgagccaatt 267180
ccaatcgtac atatggaaga tggaacaatg agaaccgttc cggttgaaga attaccatta 267240
gaattgccag ctactaagaa ttttcaaccc catgatagtg gtgaatcacc attagctaac 267300
tgtgaagatt ggttggaagt agagattgat ggtcaaaaag gtcgtcgtga aactaataca 267360
atgcctcaat gggcaggatc ttgctggtac tatattcgct atattgatcc acataatagt 267420
gaagttattt gtgatcctaa attgttagaa aagtggttgc ctgttgattt gtatgtaggt 267480
ggtgctgagc atgctgtatt acacttacta tattctcgtt tttggcataa agtattgtat 267540
gatgctggag tagtgaaatg taaagagcca tggcaaagat tattccatca aggaatgatt 267600
cttggagata ataatgaaaa aatgtctaaa tcacgtggta atgttgttaa tcctgatgat 267660
attgttgctt ctcatggtgc agattcatta agattatatg agatgtttat gggaccattg 267720
gaagctgctc ttccttggtc aacaaatgga ttagacggtt cacgtaaatg gttagatcgg 267780
gtatatcgtt tatttatcga acaagataaa ttaagtgatg aaaatgatca tagtcttgac 267840
cgtgtatatc atcaaacagt taaaaaggtt acagatgatt ttgaaacatt aggatttaat 267900
actgctattt cacaaatgat gatcttcatt aatgaatgct ataaagcaga gacagtatat 267960
aaagagtatg catttaattt tatcaaaatg ctttcttgca ttgctcctca tatttgtgaa 268020
gaaatgtggc aaatgttggg acatgatagt tcgattgcat atgaaacttg gccaacatat 268080
gatgaaaata tgttagtgag cgagacagtt gaaatgggtg ttcaagttaa cgggaaactt 268140
agagccaaga ttcaagtgac taaagatact gatgatgaag ctgtgaagga aattgcgttt 268200
gaacaagaaa atgttaaagc tcatactgag ggtaaaaata ttgtaaaagt gattgttgta 268260
aaaaacaaaa ttgtcaatat tgttgttaaa tagttataaa taaaggaaac tgtaacgcat 268320
taaaattgat atgcttcttt ctggggagac aagtgaaata ataaaaactt gtcacttagg 268380
aggaagcata ttttatgtct aaaagaaaaa tatccattga ggataaggta tatgctgtaa 268440
atttgtatct agatggaaaa gaaagccaaa atcgaattgt atctatgttt ggtgtcagca 268500
agctgtttta gattatttag atggtcgtgg ttccttggat gatatttgta aaaaatacgg 268560
aatttgtcca agattgaagt tacaactctg gataaagaag tataataatc atgaagagtt 268620
aaaatcatct gaaataggag aacacactat tatgacaaaa ggaagaaaaa ctgcatttgg 268680
aggttgtaca gagaaagctc tgaaaacgaa caaaaaaaca gacggattac tgatgagatt 268740
gaaaagctcc atacagagtc accagataga ggataatgaa gaattagaga tgatctagaa 268800
tgttatcatg acattgatgt taatgataaa cgagtactac gtactactta atatcaaatc 268860
aactattaaa tactctacta atggatgtac aggacaggct gtaaatcctc aatatatagc 268920
taaaaattta cttaatcgag agtttactac cgatgcacta aatgagaaac ggctcacaga 268980
tgtaacagaa ttccattatt atatcagaat cgaaaaacat aaaatttatt tgcaaatcgc 269040
ataaaaactg ccagtagata atctaccggc aggaaaaatt ttatattttt tcaattgtct 269100
atttgacagg ttgcagttca ctttagacgt tacagccttt tttaaataca ttattaattt 269160
tattgtatac taatgagaat tatatataaa acaataatat atagttttta gctatttttc 269220
atataagtca ctaattgatc aacggatata ccatgttgag ctaataattc atcagcatta 269280
aaatcagtat gaaaggcctt ggagatacca taattcttga ctttcatctc tgtcataccg 269340
tagaaactgc ttattctgtg cccatatcca ccttctaatt caccatcttc taaagtaata 269400
ataagacgat gattattagt caagtcattt agtaattctt catctaaacc tgttagaaat 269460
tttggattta ttacagtgat atttttaccg gtatcctctt tgtatttttg agctgttttt 269520
aaggctaatg gaagcagatt acttactccg ataatagcaa tatcattacc ttgttgaaca 269580
atttgagatt tattatggat agagtaatca gttgtgtctt cttgaccact ttcaatcatt 269640
tgtactggga ctctgattgc aattggatga tctttttggg tagttgcata tttaaacatt 269700
tgtaaatact cttctttagt tgtcggcgct aaatagatta aatttggaat atgtgcaaac 269760
attgcaatat cacataaagc tatatgagta tttgaattca tcccatagac tccagcggat 269820
agaacaagaa ttgttgctgg attattgttc agacataaat cgtgagatag ctgatcatat 269880
gtacgttgta aaaaaggagc aaaagttcca aagacaggta ttccgccatt tttagcaatc 269940
ccgctaatca ttgccatagc attttcttca gcaatgccaa catcaataaa ttgtccacgt 270000
tcgacatatt cttttcttac aggttcgatg aatcctagcc ccatcggtgt accggcattt 270060
acaacaatag cctttttatt tgcatttaat aagttagtca agctatcgaa tagggtttga 270120
tcatcttcat caacaaattt atatgttcca tcagcaacat taaatggacc accagcatgc 270180
caagcttcct tgtttacctc tgcatatggt aatccttttc ccttgattgt atggatatgc 270240
aatacgatag ggtgatcgat atttttaaca ctttcaaata attcaattaa tttttcgata 270300
tcatgcccat catctaagta tttataatca agaccaaatg atgtaaatat attgttatta 270360
cttgttccgt tagtgtctcg taattcttta agcgtttgat aaataccgcc atgattttcg 270420
gcaatacttt gatcattgtc attaacgata atgatcaagt ttttattata ttcgcctgca 270480
taatcgatag cttctagtgc ttctccacct gataaagaac catcgccaat aatagcgata 270540
atattttcgg cttttttatt caaatctctt ccaattgcta acccaagagc aagtgataca 270600
gatgtagaag tgtgaccaat tgtaaacatg tcatgttcac tttcaagtgg gttggtatat 270660
cctgttacgt catggaaatg ttcttcatct agaaatgcct cttttctgcc ggtcaatatt 270720
ttgtgtggat aagactgatg ggaaacatca aaaacgaatt tatcatttgg tgaatcaaaa 270780
acataatgta aagctactgt catttctacc atccctaaat tgggaccact atgtccgccg 270840
gctttactaa tcttattaat caatgctgct ctaacttcgt tagcaagttc ttttaattct 270900
tttctattca attttttaag atcgtttgta tcgtctattt tttctaaaaa catatttacc 270960
tcccatataa ctagatacta taaaaaatac tttttatagg tgataatatc atacatcttg 271020
aagtttactt caagtcaaga gaaaaattaa agtagtttat gagatgataa ttagaattac 271080
tgtactgaac atatttatta atagaggaaa ataagtataa taaaagaatg aagtatagag 271140
tagattaatt agtaatttta tgataagtga aaagtgataa gtaaaaaagg tgattttttg 271200
atacaatgaa gttcactaca caaagtcacc tttttcattt gattaatata attttaagca 271260
gttataatgc attttcgagg acatttttct ttgcaaagtc cgcaatttgt acatttagta 271320
taatcaatcc gtgctaaaga gttttcaata ataattgcat tattaggaca attacgagca 271380
catataccac agccaataca actaacagcg caatttttac gagctcggag agctggttca 271440
tttgaattac attttactac tgcctgtttt tgatatggaa tcaaagtaat tacattattt 271500
ggacagactc taagacattt accacatgct tggcacaagt ctggattgat aacggcaacc 271560
ccatcaataa ttgaaatggc attatattca cattctctga cacaactgcc gtatcccatg 271620
cagccgtgac tacattgttt atctccacca ccagggacga tggctgcgtt attacagtct 271680
ttgataccgt gatataagta ctgaatcgtt gcattttcgc aagtaccacc gcaacgaaca 271740
aatgctgtca ttcgcattgt ttcttcactt tctactccca tgatcattgc aatggcgtca 271800
gctacacttt ttcctccaac aggacattga ttgatctttg cttcaccagc aacaattgct 271860
ttggctagcc cgtcacatcc gggatagcca caccccccac aattatttcc aggaagttct 271920
tcacgaattt gaatttcttt ttcattaaca gtaatggcaa atttttcact agcaattgtc 271980
agaagaatac caataagtaa accgattgca cctacaataa tggccgcaat tataatttca 272040
ttcatcttat attctcctcc ttatattaga cctgaaaagc caatgaatgc aattgccatc 272100
agtcctgctg tgattagtac aatgggggaa ccttggaatg aaacaggaat atcattatca 272160
gcgatttttt cacgtatccc agccataata acgatggcaa tcgtaaatcc aacagctgtt 272220
ccaaaactac aaacaagact tgtcaaaata tcataattat tttgaacatt tgtgatagca 272280
actcctaaaa cggcacagtt agttgtgata agaggaagat atactcccaa agaactatat 272340
aagccagagc tatatttttt taagaacatt tcaactagct gcaccaaagc agcaataact 272400
aagatgaagg taacagtgtt taaatattct aaatggaaga gtactagtat tttgtaaact 272460
aaacttgttg caattgaagc aatagacatt acaaagatga cagcaccacc cattcctgct 272520
gctgtttcaa ttttttttga tactcctaaa aaaggacata gacctaagaa ttgacttaag 272580
acaacattat ttactaaagc gacactaatt aataataaaa tcattcccgt catttatttt 272640
tcctccttta aatcacaaag tgccttttca tcactgctac gacaatgaag acaatcatga 272700
ttacaattac catctttgtt tttattagtt gcacttggca gttttaaacg gttttgaata 272760
gccgttagac cagctaaaac aaagaaagcg ccaggtgcca ttacaaagat agttacaggt 272820
tcaagatgag caaaaaagct ataaatatta gtgccaacta aatctttaaa aagtggcgca 272880
aactcaattc caaaaaaagt accactgccc aacatttctc taattaaacc aatacaagtc 272940
agtgcaagcg taaaacctag ccccatacca acaccatcaa ataacgataa aacgcaacta 273000
tgttttgaag cgtaagcttc agctcgtcct aaaatgatac aattaaccac aattagagga 273060
atatagatcc ctaatgtatc atataatgaa ggcaaatatg cttgtaatag taattggaca 273120
attgttacca ttgaagcgac aattacgata taagaaggaa ttcgcattct ttcagggatt 273180
atttttcgta agaacgaaat cataaaattt gatgcggcaa ggacaatcat cgttgttaag 273240
cccattccta atccattgac agaagaagtt gttactgcaa gagtaggaca cattcctaac 273300
attaaaatca aagttggatt ttcttttatg attccattat aaagacgttc aacatattta 273360
ttcatgatta gcctccttga tttcctggtt gattgctaag gctccgttaa tagcattgtt 273420
aaaagctgat gaagtaattg tagctccgct tagagcatca atttcatctt cattttgctt 273480
accagttttg gtgattttaa aatcagttac tgatttatga taatattgat ttttaaaatt 273540
atcattttta gcattcattc ctaatccaac cgtctcatca attgagagga cttcaattcc 273600
cgtaatttca ttattagtat caattccaac aactaatgtg atatcaccgc cataaccatc 273660
ttcagtagtg actttgacaa catgtcctat taattctttt ttatcatttg taacgactaa 273720
aacgtcgtct atcacaatgc cattttcacc aaagttatat tttttgtctt ttataacatt 273780
aggaaaattt ttaacaagtt gatttatttg tttattatta tcaaaatttt gaccttcttt 273840
aaaaacactt cgataagaat cttgtatgat tttttcattt tgtctagcaa ttgggtcttt 273900
ggtaatagaa ttaaccatag ctagagataa actagcagca actgtaatta caacaaaaac 273960
gagaatatct tttagaagat tttttttcat tatgctttac ctccactacc ttttatttta 274020
ggcactgtta ctttttcaat caaagggaca agtaaattag taatgataat agcaaatgac 274080
attccctcag gagtattacc atagagccta aaaacagcag ctaatattcc aataaccagt 274140
ccataaataa ttttaccggt tggagtaatc ggacttgtca catagtcagt agccatgaaa 274200
aatgccccaa tcattaaacc gccaccacaa atttgttgta ataaaaatag actgttaaag 274260
ttattattga tcaaaatgat taaagaaaat gaaaatagga tacacaacgg tattttagga 274320
ctaattactt ttcgataaat taggtagaca gcgcctaaaa gcagagcaat tactgatgtt 274380
tcaccaatcg taccactagt atttcctata aacattttga gaagattgac attttgtcca 274440
ttttgtatca ttgccagcgg agtagcacta gtacttgcgt cgatgctaac aaagctgttc 274500
atttttccgg caaatgaaat taataaaaaa catcgagctg ctaaagcagg attcataaag 274560
ttctgaccaa gtccaccaaa aagttgctta acaattataa ctgcgaatat acttcccaaa 274620
gcaaccatcc acaatggcaa tgagcttgat aggcataacg ctaataataa gcctgtgatg 274680
gctgcggagc cgtctttaat cgtgactggc agcttcatca atcgttgata caaatattca 274740
cttagaacag ctgtaataat agcagttgta ataacaagaa acgcattaaa tccaaattga 274800
taaattccaa aaaaagttgc tggtaataaa gaaatgatta cgtcatacat aatattttta 274860
gttgtaattg aactacgaat atggggagca gtagacacat taaataaatt atccattatt 274920
ttgctccttt cttgcgatcg tcattaattg ctttttttat ttttttaaat gattgtgtca 274980
tgtttcgctt tgcaggacat gtgaaggtac agcagccgca ctccatacaa tcgttgccgt 275040
gaacctttaa aaagttttct ttatcgcctg ttctggcata acggtatagt aattgtggaa 275100
taagaccgat agggcaaaca tcgacgcatc ggccgcagtg aatgcacgca gttggagcgg 275160
ttttagatac ttcatcttca cttaggcaaa ctaaagcaga agaagtttta gaaactggta 275220
catctaaatt aaataaagca gtacccatca tgggaccacc agaaatgatt ttttgaggat 275280
gtattttaaa acctccacaa gcgtcaacaa gggtctgata tttagttcct aggcgaacct 275340
taaaattttg tggttgaaag attgcatcac cagttaccgt tacaatcttt tcaattagtg 275400
gaatatttaa ggcaacggcc tcatagatag caataataga tgcaacattg ctgacaatac 275460
agccaacatc agctggcaac atcccatcta caattgtttg attagttaat actttaatca 275520
atacgcgttc acttccttga gggtattttg ttggtaaggc tgctatttca attttatctt 275580
catctacaac gacttttttt aaatgagcta atgcttctgg cttattatct tcaatagcaa 275640
taattgcttt ggcattttta aataactgta attgaatttt gatgccagcg attaatttat 275700
ctgtttcttc tagcattaaa cgatagtcag aagttaaata gggctcacat tctgcaccgt 275760
tgataattac atatttaatt gagtcatcat ctttaggggt attttttatt gcgctgggga 275820
agccggcgcc acctaaacca acaattcctg cgtgagcgat aagttcacga atttgcatac 275880
tgctataatt atgataatca tttgttgtgt tgtattctgg aatactttga tattggtgat 275940
cgttagtaat aacgatacaa tcaacaaaaa aaccagtagg ggcaagtcgt aaatcaattg 276000
ttttaacggt tccagagaca gaactagcaa cattggcaga aatcataccg tttccattag 276060
caataatttg gccaactaaa acatgatcac ctttagcaac gatagcttta gctggagcac 276120
caatatgctg tgataatgga taaatcagtt catcaccagg atttaatagt ttgattggat 276180
gattggcgga aagactttta ttatcatggg gatggattcc gcctttaaaa cttagtattc 276240
tcatttgaat taaactcctt ttttggacta tattttaatt atagactttt tataattaat 276300
attaaatagt ttagacaagt taaaaaatta acttaaaaag caatcctttc aagaggattg 276360
cttttactag tttataaatg aaattgagat tcatcaagac gtagactata accttgtggg 276420
tgtttacaaa ctgggcagat cgttagtgca tcagtacctt cataaataaa accacagttc 276480
atacacatcc attttacagt agactggtca ttaaataatt taccactggt taataaatta 276540
tgatattttt taaaacgttc atggtgatag tgttcaatct cacaaatcat gtaaaaagtt 276600
gttgcaattt caacataacc ttcttcttta gcttcatcac caaattgctt gtagatagat 276660
gttgcttcat cgtattcgtg ttgtgctgct tgttctaata acgaacttaa atcctgatct 276720
agatcaacag gataattagc ctccattgaa acattagcat ctttaaaaac atctttaaga 276780
taattgtaaa aaactatcgc atgctctttc tcttgatttg cagtaaaata aagcatatct 276840
tgtaaaatag ccattccatt cttacctgcg actttagcag ccatttcata acgcattcga 276900
gcttgacatt caccagcaaa agctcttaat aaatttgttt tggtttttgt ttccatatat 276960
aagttacctc cacttttatt tttaacaaaa taaaagaaga ttaaacttaa tcttctaaga 277020
atcaaataat ctctttaata ataattaaaa tattataacg ctgatataga tactgctaac 277080
aagacaaata atctagttgt tcatatcttt attcattcca gttaattcca tatattcagt 277140
tttaacattt ttcaataatt gcataaatgt ccaatttaca tttgtttgag ttacaattgc 277200
ctttaacgga atgaaaggaa tgtttgcttc tttaaaaatt tgtaatagca aatcaacttg 277260
tttatcttca aaaccagcca taaccatcat gtcatcttgt ggaatctctg ttaatgcttc 277320
agttccacgt tcaaaattat cagcacctaa aatataccca atcgggctca ttaaatcact 277380
tgatttaaca atgattactt caacattcag tttttcaaga attgaaataa ttgctttacc 277440
agcatcagtt ttatcaatat tgtataataa tacagtttct tgcatatgta ttgcctcgct 277500
ttcgtttaat aggttatcat atttatggtt aacgttcaac taagttgact taatgtgcta 277560
taatttattc gggtaggtga gataatgcgg tattatttag aaaaagaaat tacaaatagt 277620
tataaagaag gaagcttagt tattgatatt cttagtaaag aagatttcat aaaccagtat 277680
caaaaggaaa atcatgcaaa ccatgtgatt aggcatattg gggatattat gtactgtaaa 277740
gtagaattat tttacgatgt gatttgcgga gcgtttgtta tacctgacaa aaaggattta 277800
aaaataaaac attgttttag tttttattta acagaacaaa aaatgatttt tattgatgat 277860
aacgattatg tgatgaaact tattgaaaaa atgaaagata catatactaa taatcgtcta 277920
agtttgaaca aattttttca tgatttgatt ttcttaataa ctgttgatga tggaatgtat 277980
ttacaagaat atgctgatcg tttacaggtc atcgaagaca aaatagcttt taatttcaat 278040
agtcaaataa ataatgagat aatcttgctg cgtaaagaac tattaatttt aaattcctat 278100
tataatcagt tgggggatat gatcgatatt ttaagtgata atgaatcaga tttcttaaat 278160
gattatgaat gtcatttatt cagcatgcag gcacgtagga ttgatcgttt ggataaccag 278220
ttaaatgctt taaaagatta ttctttgcaa ataaaggaaa tgtatcaaaa taaaattgat 278280
acccaccaaa ataaaattat gactgtttta acagttgcaa caactatttt cttcccgtta 278340
tcgattatca caggatggta tggaatgaat tttaaaaata tgccagagtt aaataatcct 278400
tatggttata ttattgttat tggagcaagt attttagttg taattattga aatgttaatt 278460
ttgaaaaaga aaaaattctt ttagaaaaaa atgttgacgt agtcaataaa aaaaggtata 278520
gtaaataagc aacaaatgat agcagcacat agagttttga aaagagcgtt tataacttaa 278580
gtttgtagag tagctagctg caaagtgaaa tacttaatat aaacacaatt caaataatct 278640
atgcaatgtt attgttttat gcaaataaaa caataaatgg aggaagacaa atgtcacgtt 278700
acacaggacc tcaatggaaa ttatctcgtc gtttaggatt ctctacttta gaaaatggta 278760
aagaattaaa taagagagct tatgctccag gtcaacatgg tcaaaaaaga aaaaaacaaa 278820
cagaatatgg tttacaatta gctgaaaagc aaaaagtaag acatatgtat ggagtaaatg 278880
aaaaacaatt ccataacaca ttcaaacaag caggtaaaat ggaaggtatc catggttata 278940
atttcttctg cttattagaa agaagattag ataatgttgt ttacagatta ggatttgcac 279000
ctacaagaag agctgcaaga caattagtaa accacggtca tttcttagta aatggaatta 279060
agactgatat tccatcattc cgcgttaaag ttggagatgt tattgaagtt aaagaaaaat 279120
ctaaaaattt agcaatcatt aaagctagct tagaagctag agtacatact cctgcttttg 279180
tagaagttga tgatactaaa ttaactggaa aacttgctcg tttaccagaa agatctgaat 279240
taaatcaaga aatcaatgag tcattaatcg ttgaatacta taaccgtatg ggataatccc 279300
tacgggatta aactggtata tcttaactat gcagaagtta ggatatactt ttttttgaat 279360
ttgattcttc gttagattat taattgctgg tttaaaacga cagttttgcc atcctgttta 279420
aagaacgagc gcacaggttg atagcaatta taattattta taaaatggta agaaaattat 279480
tttttattgg tttaaaatta aaaataatta aaatgatatt ccggataacc ctaagaaaaa 279540
atcatataaa attgaaaaaa gtatttgcat aaaaaattaa tttaataatg tattaatttt 279600
gataatttga tataatcaaa ttaatgtgga ggtatgtatg acagatagta gaatttgtat 279660
tgccttggat tttcaaaata aggcagaagt aaaagaattt ttggaaaaat tcaatgatga 279720
aaaactatat gtaaaagttg gaatggaact attttatggt gaaggtattg aaatcatcaa 279780
aatgattaaa gaaatgggac ataacatttt tttagattta aaattacatg atattcctaa 279840
tactgtaaaa agtgcaatga agcaactagc aaaattagaa gtagatatgg tcaatgttca 279900
tgcttcagga agtatcgcaa tgatgaaagc tgcaattgaa ggattagaag caggcaagac 279960
aggtgataaa cgacctttat gtatcgccgt tacatgttta acgtcacttg atcaagaagt 280020
gctagataac gagcttttaa ttaacgatac attagaaaat gtcgttttaa agtgggctac 280080
taatgctaaa gaagcaggac ttgatggtgt tgtttgttca ccattagaat ctaaagtgat 280140
tcatgataat ttaggaatgg aattcataac agtaacgcca ggaattcgtt tagctgatga 280200
tagcgtaaat gatcaaaaac gggttactac tccggcgatg gcacgcgaat taacatctag 280260
ttatatcgta gtaggtagaa cgattactgg atctgctgat ccatacgcaa catataaaaa 280320
agtatatcaa gattttcaag ggtagaggag aagaataatg aaagaattaa ttgctaaaga 280380
tttattagat attcaagcgg tttttttaag accaaatgaa ccatttacat gggctagtgg 280440
aattaaatca ccgatttatt gtgataatcg tttaacatta tcatatccaa aagttcgtaa 280500
agatgtagaa actggactag ctaaattagt tcaagaaaat tttccagaag cagaatgctt 280560
aatgggaaca gctactgcgg gaattgctca tgctgcatta gtggcagata ttttggaatt 280620
accaatggga tatgtccgtg gtggggcaaa aagccatggt cgtaacaatc ggatcgaagg 280680
aaaagtagaa cccggcatga aagttgttgt ggtagaagac ctgatttcaa cgggggggag 280740
ttcattagaa tgcgttgaag cgctaaaaga agccggttgc gaagtaattg gaatgattgc 280800
tattttcaca tatggattac caaaagcaac aattaatttt gaagcggctg aatgtaaata 280860
tgtaacattg actgattatg atacattgat cggtgtagca aaagaaaatg actatattaa 280920
agaagctgat atggaaaaat taaaggcttg gaaaaaagat ccaagtgacg aaagctggat 280980
gagtaaatag aaggtaaaaa caccttcttt ttttatattt tccccctaaa ataaagatat 281040
tttaattgca ttatcattgt gctataatta taatgctatt gttgtaaata aaagtagctt 281100
tggaggtaga aaatgctaaa aagtattaaa tatgttctaa aagagaattt ctcaaattta 281160
tttagaatat attcaatttc gaaatatgaa ttattatctg atattcgtga ttcccgtttg 281220
gggatttttt ggaattttgc taatccattg attcaaattt taacatatta ttttgttttt 281280
ggtttagtaa tgaatcgtaa agatgtagat ggaattcctt ttattcaatg gatgttggcg 281340
ggaatggttg tttggttttt tattaatcct tgtattactc aaggggctaa tgccattttt 281400
tcaaagacgg gtgtaattac taaaatgaaa tttccagtta gtgttttacc agctacggta 281460
gttttaaagg aattatttaa tcatgcctgt atattgcttt taatgattat tttttattgt 281520
actcaaggtg tctatccatc aatcgagtgg ttgggaatta tatattattg ctttgcggcc 281580
tgctgttttg ctgtgagttt agcgatgatt acatctgtgc ttaatatgat tgctcgagat 281640
actcgtaagt tgattttagc gtgtatgcgt ttgattttat atttaacacc tattttatgg 281700
ccgatttctc gttttagtga acagacgtta ttgtttgata ttattcgttt tgtcatgaaa 281760
atcaatccaa tctattatat tgtatgtggg tatcgagatt gttttttata tcaccttgga 281820
tttatgcatt attggaaaca aatgctggct ttctggggga ttactggaat actgtttgtt 281880
gttggctgtt atatgatgta taaattcaaa cataaattta ttgatatgat ctaggtggta 281940
gaaatggaaa attacgcaat taaatttgaa aatgtttcaa aaatatataa attgaaaaag 282000
aaaaatgatg gtaatactaa aagtagtgaa acaaaaagat tttatgcttt aaaaaatatt 282060
agttttgaaa ttccacaagg ggaagtagta gggattttag gaactaatgg ctcaggaaaa 282120
tcaactctgt cacttatctt ggcgggaatt agcgaaatcg atgagggtgt catgcatatt 282180
aatggtgaac aatcattggt tgctattaat accggtttaa ataaacagct aacaggttta 282240
gaaaacatta atgttaaagg tgctttatta ggactatcaa aaaagcagat tcaggagatt 282300
attgatggtg ttattgaatt tgcggagcta ggagactttt tatatcaacc tgtaaaaaaa 282360
tattctagcg ggatgaaatc acgacttggt ttttcaatct ctttatattt aaatccagat 282420
attattatcg ttgatgaagc tttatcggta ggtgataaag gttttgcaca aaagtgcata 282480
aataaaatga atgaattaaa agatgaaggt aaaacgatta tatttatttc acattcattg 282540
cctcaagttc gaaatttttg tcaaacagca atgtggattg agggaggaat gttaaaagaa 282600
tatggtgaag tcggggaagt atgtgatcat tatggtgaat atgttgatta ctataacagt 282660
ttaacgaaca aagaaaaggc taaaataaga gataataaat ttaaaaaacg aattgttcaa 282720
aatcctcaaa ttggattttg ggaaaaagtt ttagatcgga taaaaggata ggtgaaaata 282780
atgaagaagg ttattacata cggaacattt gatttatttc atgtaggtca tttgaatatt 282840
attaaaagag caaaagcgct gggtgattac ttgattgttg cggtaagtag tgatgcattt 282900
aatgcgcaga aggggaaaaa ggcatatcat agtgatcatg atcgaaaatt gattttagag 282960
gcgattagat acgttgatga agttattttt gaggaatctt gggatcaaaa aattaaagat 283020
gttcaagaac atgatgtaga tgtatttgta atgggtgatg attgggaagg taaatttgat 283080
tttttaaagg attactgtga agttgtctat ttaccaagaa ctgatggtat ttcaacaaca 283140
aaaattaagg acgatctaca taaataggtg taaagatgaa acttagtata attatccctt 283200
acgatcgtta caaacagtat ttacatgatt gtctagaaag tgtttatgaa cagcggttaa 283260
atgattatga aactttactt gttgtaaata ataaaaaaga gattgatcaa gatatcaaag 283320
cgtatgatat taatttaaaa atccttgaag ctggagaaaa ttctagtgtt gctaaaaaaa 283380
gaaatattgg cttagaacag gcaagtggtg aatatatcta ttttattgat tgtgatgatt 283440
atttgatgcc aaatacttta aaattattaa ttacttgtgc taatcaaaat gatttagatt 283500
tagttgcagg aattagacgc tttacatggt tcaaaaagaa agtttttgag accatgggtg 283560
atgaaaaaaa taatgaatta aacttaaaag ataaagatca tgattatgat gataaattta 283620
ttgaaaaagt atatgaccaa aataatgttg atgaatatat ggtagatgtt ttaattcgga 283680
gccgacatgc tattcgtaat atttctgtct taaatgtttt aataaaaaag aaactgattg 283740
atgagcatca aattcgtttt aacgaagatt ttttctatta cactgatgtt ccttttgtaa 283800
tccaattagt taattacgca aagagttttg atcgtgttga acaagcaatt tttgttaaaa 283860
gaaaacataa tgatccaatc aatacacctg ctttatcaca aataaaagat tctgaaaata 283920
aatttgatga atttttgatg gcttatcgct atagtgcttc tttagtagct ccagatagtt 283980
atattcgtta ttatttagat tcgaaaatgc ttagatatta cacaaagttt tttgcacgaa 284040
agattcggcg cagtaaagat gatatttggc gtaacgaacg atttaaagca atgggagaaa 284100
tattaaaaaa tattcatcct cgtttattga ataaaagttc tcgttatagt aaaaaaatga 284160
tcaaagctgg tctaaatggt gatcttgagt tagcaaagaa gactgtaagc cggcatttag 284220
caaaaataaa gtttaaaaag atcttaaaaa ataaaaacga gatgaataaa tatttatatc 284280
gtcataaata tattaataaa ccgcttgaag aaaatacggt tatgtttgaa acttttatgg 284340
gaaaaagtta tgcagattca cctaaatata tttacgaata tttagcgaag aattatccag 284400
gtaaatataa gtttatttgg gtattaaatg atcctaaaga aaaattgcct tacgaaggta 284460
agattgtcaa aagattcaca agggaatatg cttattattt aggcgtttct aaatattttg 284520
tttttaatat tcgtcagcca ttatggttta gaaagcggga ggaacaagtt tttttagaaa 284580
cgtggcacgg aacgccactg aaacgtttag cgtttgatca agaagaggtt actgctgctt 284640
cgccgaccta taaagctcaa ttttatcgtc aaaaacaaga atgggattat ttgattgcac 284700
cgaataaatt ctctagtgat attttcaaaa gttgttttat gtacgatggt aacatgctgg 284760
aaacaggata tccaagaaat gatttattat cgttaccaaa ccgtgatgca atagctttag 284820
aattgaagaa aaaattaggg attcctctag ataaaaagac tattttgtat gctccgacat 284880
ggcgtgatga tgagtattat ggaaatggta aatataagtt taaattgaaa ttagatttag 284940
atttattaaa gcagcagctt ggtgatgaat atgttgtatt gttaagaaca catcattata 285000
ttgctgatgc attagatgtt acgggactag aagagtttgc gtataatttg agtaagtatg 285060
atgatattac agaaatttat ttaattagtg atatttgtat tacggattat tctagtgtgt 285120
tttttgacta tgctaattta aaaaggccga tgttattcta tacgtatgat ttagataaat 285180
atcgtgatgt attaagaggt ttttatattg atatggaaac agaattacca ggaccattgg 285240
tttatactac tgaagaagtt attgataaaa tcaagaatct gaatagtttg aatcaagaat 285300
atcaacaacg ttatgaacaa ttttatgaac gtttttgttc atgggaagat gggaatgctg 285360
ctatgcgagt tgttgaagca gtttttaaat aaggggttta ccccttattt ttatgggagg 285420
aaagtaaatg aaaatattaa agaaactact cggtaagtta atcagaattt tatatcgatt 285480
cgtatatcga tttattcctt gtcaggaaaa aacaattctt tttatttctt ttcatggtcg 285540
cggttattct gataatccaa tggcaattca ccaatatctt tcaaaacatt cacaatatgc 285600
tgattatcgt tgcatttatg caataaaaaa tcataaacaa aaaaaattaa aaattgaaaa 285660
tgctagaatt attgagtatt ttagtattgc ttattttttc tatctagcgc gtagtaaata 285720
ttggattgct aattgtaagc tcccaaaata tgttttgaaa aaagatagcc aagtttattt 285780
acaaacatgg catgggacac cattaaaaaa attagcacat gatattgaag ttccagaagg 285840
aacaaccttt tatcgtagtg aaatgagcgt tgaagaaatg cgttcaacct acgataatga 285900
tgtaagtaag tataattata tgattagtcc tagtgctttt acaactgaag tctttcaaag 285960
tgcttttgcg attgagagag agcgcttgat tgaaacggga tatccacgaa atgatatttt 286020
atcaaattat aattctgatg atataaaaaa aataaaagat aaattaaatt tacctgaggg 286080
taagaagata attttatatg cgccaacttg gcgtgacaat tcatataatt taaaagggta 286140
tacatttaaa ttagaagttg actttaaaaa gtggcaaaaa attctaggta cagattatat 286200
tgttattttt aaaccccatt atttaattgt aaatgatttt gatttagagg cagttaaaga 286260
atttgtctac tacattgatc ctaaagaaga tattagcagc ttgtatttaa ttgccgatgt 286320
cttagttaca gattattcaa gtgtattttt tgattatgca atattaaaac gaccaattta 286380
tttttttatg tatgatttag acacttatcg tgatgagtta agaggctttt atttagatat 286440
ttatcatgat ttaccaggcg atgttattga aagtgaggat gaattgatcc aaaaaatttt 286500
ctctgaaaaa tttgactata atcgattgca aatatttaat gaacagttta ataatcatga 286560
agatggcaat gcgagtaaac gggttattga aattttatta aagtaggtga tgagatggga 286620
ataaagaaaa ttattattaa tattatctta aaaatagcca atatatttgt tttaagatgt 286680
tcaatcaagc aaggacaaat agcctttatt tcattagagt cgaatcaact tgaaagtgat 286740
cttgaactta tttatcagga gttaaaaaaa gaaaacaaat atagtttaaa aatggtatta 286800
ataaattata ataaaaaaag tttaattaac aattttttgt atatgttaaa ctgtattaag 286860
caaatttatg taattaatac ttctaaagtt gttttgatta cagacaataa ctatgtaatt 286920
agtaatttta aacgacctgg cgttaaagtt attcaggtat ggcatgcgac tggagcaatc 286980
aaaaagtttg gaaatgctat caaacgtgaa tatcctatta aaaattatga ctatgtgatt 287040
gcaaatagtg attattggaa gcagccttat caagaagctt tcaacgtttc cgagcagggc 287100
gttattatta caggaatgcc acgtgtggat catcttgttg atccatatta tttaacacaa 287160
gcgaaagcac gtatgtatag tagatatccg attctaaaag gaaaaaaggt tattttatat 287220
gcaccgactt ttagaggaaa tatttatcag ggttttaaaa cagttgactt tgatgctcaa 287280
gcagttttaa atgcactggg agaagaatac gtaataatct ttaaatttca cccattgtta 287340
ttgaaaacta cgctatcaga cgattctaga gtgattaata tgaatcatga aaatactcat 287400
gatttattcg cagtttgtga tgtcttgatt tctgatttct catcaattat ctttgattat 287460
tccttattaa ataaaccaat gtgttttttt gttccggatt tagatgaata tattgaaaca 287520
ttaggatgtt ttgtggatta tcgaagggtc atgcccggag caatctgtta taatgaaacg 287580
caagttattg cagccttgca aggtaataaa aaatatgata ttaaggcatt tagagatatg 287640
ttttttaaat atcaagatgg tcataataca caaagaattg ttatgtttat cgataaatta 287700
ataaacacca agaattaatt cttggtgttt atttaatgat tttcattcgc caaataatca 287760
cggacatttg ataaattgtc catgatctta ttagtcatta tcgcaaactt atgatcaggg 287820
tattttaaat caggaataca aattacttta atgcctgcac tataggcagc gttaattccg 287880
gattcagaat cttcgagaac cagagcttca tcgggcgtaa ttcctaattt ttggcatgat 287940
tttaaaaata cttcaggatc aggttttcct tttgttactt cgtcaccaca aatggaatca 288000
tcaaaatatt tttgtaaacc agataattct aaaatatgat caacacgatg acgctgtgaa 288060
ctggttgcaa caattgtttt atagtcgttt tcttttaaat actttagtaa ctcaattaat 288120
ccttctttta aaggaacccc ttcattttca aataagtcag ccatatattg atgaactgct 288180
ttaattgttt cctcaacatc aaaatcgtcg ccataatctt tatggaaaag ctcatagact 288240
gctttaacag gctttcctaa aagagtttta taggcttcta atgacaatgt taaattatgt 288300
ttagctaata catgcttata tccctcgaat gtaactctct cactatcaat cattaaacca 288360
tccatatcaa aaattactgc tgttatcatc tttttacctc cacgcaaata tcatatcata 288420
attatccgat tagtaaaaag attttcatag aataaaaaaa gttctaattc atatactgca 288480
ctaaaggagt tgtagatatg atacatagag gggaaattta ttatgctgat ttatctccgg 288540
tagtggggag tgaacaagga ggatatcgac ctgtgattgt tttacaaaat aataagggca 288600
atcgatattc gacaacagtg attattgcgc caatttcttc acgattaaca aaaaatccgt 288660
taccaaccca tgtgatggtt gattgcagtt cattggaaaa aaagagtgta gttttactag 288720
aacaaattag aacgattgat aaacagcgaa ttaaagaaaa agttggaatg attgatagcc 288780
aagtaatgaa tctgattaat caagcaatta agacaagctt ggatattaaa tagtttcctt 288840
ttgagtcaga tatttgctat aatagcccca tggaggtaga ggaaagatga atgttcgtga 288900
tattaaatta aaggctaaaa gtgttttagt taatcgtaat aatatagtta cagtatttgt 288960
gtttattagt gtaataacaa ctttggctaa ttatattggt tcagaaattg gcggggtgat 289020
accatttctt tcattgattg taactattat aatgttgccc tttggtcatg ggaatgtggt 289080
aactgcatta aaaacagtca atgaacaagg tgatgaggtc actattgaac aagatggggt 289140
agtcggatta agacgtttta aagatttatt tggcacatat tttattagag aaatattatt 289200
attggtgatt atgatgctgc ttggattaat catattcgta attgctagat ttacagtaga 289260
cagtaatgtt ttttctcaat taggagcaat tattgagcaa gctgctgtat actctactaa 289320
tgtaagtgca tatttaaatg atccaactgt aattgaagca ttaggaacac taggagtaat 289380
cttttttatt ggtatcatca ttattgcaat tgtagcgttt atttatagtt tggtatttgc 289440
tttaacacct tttgtattag aaaaatataa tatacgcggt gccaaggcaa tgagtgaatc 289500
agctcgttta atgaaaggac ataaacgaac tttatttatg ctgtatttgt catatttagg 289560
atgggctatc ttagtattag tactttctgc tgttgttgag atgattttac cgattccatt 289620
aattttgaat attatcgtgg cggctttgac tacttatttg tttggtgctg aactaaatac 289680
tagtttagca gtattttttg aagaaattga tttagaagat aaaaataata tttaacgagg 289740
tgttaatttg aatttgataa aaaaaattaa attaaatagt aggcaaaagg cgataggggt 289800
catattgatt tttccctggt atctttattt tgcaccaatt gtaattaatt attttttgaa 289860
gctatataca gtatatatag ctaatgattt ttcaactaat agtttaaatg cattttttaa 289920
tttattcatc ggaattgcaa ctgctattcc tttgattatt gtgtttaagg gttttattaa 289980
agaaaactgg cttgttttta aaaaagactt tttggaaaat ataatatggg tgcttacgat 290040
cgggattggt ttagcatatt tattttcaat tgcaggggaa ctgattgtca atcttgtagc 290100
ccctcaatca ggcgaagcag ctaaccagac attagtggaa actcttgtgc aatctaattt 290160
tctattaatg ttttttcaat cagtaattat tgcaccattt attgaagagt tgttatttag 290220
aggtctgatt ttcaacagtt tacggcaaaa aaatatggtt tgggctcatt tgatttcagc 290280
attcctattt ggcttgttac atgtttacag ctatatttta gctggtgata tgagtgaatg 290340
gattaaattg attccatata tgatggcagg tttatctttt tcaatcgtat atgaaaaacg 290400
tcaaacaatt atagctccga tcattttaca tgctgcaaaa aatctaatcg cagtattgtt 290460
aatggcgacg atgttttaaa cactatgcat gacatagtgt tttttattgt gaaacaaaaa 290520
ccacgtgcta tgcgcgtggt aacaataaag ctttagcgtc tgggtaaaaa acctcctcgt 290580
gatataataa ttgtagcctg gcagctgcaa ataaaataac gaggaggtta gtctatgaaa 290640
gacacaaaaa gtttatcaca tacatcatat agatgtaaat ctcatattgt aatagtacca 290700
aaatttagaa ggatggtaat atacaataaa ttaagacatg atataagatt aattataaag 290760
accttaattg aaagaaaacc gggaatagag ctgatagaag gagagttatg tcctgatcat 290820
attcaccttc tattagaaat accaccaaag tattctgtgg cggagttcat gggatacctg 290880
aaaagcaagt caacgcttat gatatttgat cgtcatgcaa gtatggaata taaatatgga 290940
aatcgaaaat tttgggcaag aggctatttt gtagatacag taggaaagaa cgagaagaca 291000
gtgagagaat atattcaaaa tcagttggcg gaagataagt tgagtaatca aatgagtatg 291060
gaagaattta ttgacccgtt cacaggagaa ccagtggaag ggtacaagaa aaagaaaaaa 291120
agtaaaagac cctttgaggg tcagtgagca aatgacgttg cggttgtcaa ggcgttcagt 291180
ggtcgaatga ctagcgcaac agcatgccct tacagggcga gtacgtcttt taggcgtggt 291240
tatgatttta taataaaaaa accgtaaaac ttatataaat aagaattacg gaaatttatt 291300
aatggtctcc cctcacggtc tcgaaccgtg gacccacaga ttaagagtct gttgctctac 291360
caactgagct aaggagagag gacagatatt ataatacacc tatttaaaca taaaagcaag 291420
ttaaatttaa tgaaaaatga cattagctat gctataatta ctaggtgaat ggagtgatct 291480
ggcaatgttc tacaaacaaa ctattaacaa tataaaagta gttattttat cattggatgg 291540
aggattatta gatctaaatc ggcttagatt taattatttt aaaaggattt gtaaaactca 291600
caattttgaa ttaactaaag atattttcga ggaagccctt ggaaatatga aaacaatgta 291660
taatgatttt ccaatttcta aagatattaa tcccgatgat attaataagt tgattgaacg 291720
tgatttatac gagtatgcaa agttaaagcc tgagacaata aaaaaagagg gaacggatga 291780
actgttacaa ttttttaaac aaaaagagat taaaattgct gtggtttcaa ctcataaaac 291840
aaaacgtgca attcaatatt tacaattaac aagattgtat gacaaagttg attttgttat 291900
tggcggcgat agcgataatc taccattacc agatactgct gttttaaaaa caactcttga 291960
acaaatgaac tgcaaaccaa gtgaggcaat tgtaattgca aactatccaa atcttcttta 292020
tgcagctaat caatgtttaa tcaatgtaat ttatctaagt gatttatgct tggtacaaga 292080
atcgattggt ccaagggtat ttaaaattgc aagaaataat ttagaaatta ttaatatttt 292140
tctttttgca cgttacgata caatggaaat attttcgccg ttattaggga tgtctagtga 292200
tatggatatt gaaacactag ataaaacata cgctaagctg cttgaagagt atcaaaatga 292260
tcagcagttg attgaactag ttcgcaatac atatcattat tttttgggag aaattgcaaa 292320
tcgtgaagct gataccgtca atacatcgtt atttgaagat gaagatgtta ttgtagcgcc 292380
agtggatgat gaacattttt ctaatcccca aagtattgca actttggaaa agtcaattga 292440
agaggtttta gagtcagaag aagtttcaga aactgacaac gaaattgccg atactgtttt 292500
taaaagagag aatttatatc aggatgatga attttcaaaa acaagaacag cgataggatg 292560
tgatcctgaa cgcgttaatg aattgatgga tattattaat ggtaattctg gaactaagtt 292620
ggaagaggga gaattatttg aaaagtcaaa tgatgaaata ttattagaaa aacggggact 292680
attgtcttat tttattaatt ttgtctatac tgttatcgtg gtgggactga tatcattttt 292740
aggattaata atttttatcg gttttgaaga ttttattcag agaccaggta ttgttgctgg 292800
aataattaaa agcattattg atttttatgt taatctagtt ttatccatat atgcggttat 292860
ttttaacagc ttaaatgctc tactaagttt tattcctgat tattctagtt taattgcggg 292920
taatggttta ttatcgacaa tggcagtaaa attagtattg ttcattattt ttaatgtaat 292980
aatagtctat atagttaaaa tgatttattt attaattaca gaagcggagg aagatgatgc 293040
gaattttgca gaagattaaa gaaatagatg ttaaaacatc gcactttttt ccgcagtttt 293100
atcatcatcg tttttttagt ggtgcgatga agtttattgc tggaattggt gattttggaa 293160
tgatttggct tgttttaatt ttacttttaa gtcttaatga taaaacacag ctgctttctc 293220
aaaaaatgct ggcagcgcta atattagcaa cagtcatcgg tcaagtgaca attaagtcga 293280
ttgtaaggcg taagcgacca tgtcatacat atcatgatgt tgaaatgttg attccagttc 293340
cgagtgatta ttcatttcct tcaggacata ctacttcaag ctttgcatgc gcaacgactg 293400
tatgtttctt ttttcctaga gtcggcttta tttgcatgat ttttgctgca ttaatggctt 293460
tttcaagatt gtatttgttt gtccattatt tgagcgatgt tacttttgca attgttttgg 293520
gaattagtgt tggaataatt gttatgttat tttagtgtga taaaaggagc aagggtctgc 293580
tcctttaaaa aaataaaaaa attatttttt aaataagact gatttaaacg aaataatttg 293640
cttttttatc aggtagagta agtttttata gaaaaaagtt ggctaaaatt attgcaaaaa 293700
ctttttacat atgatattat gtttaagcaa cagacggaga catactcaag aggctgaaga 293760
ggcgcccctg ctaagggtgt aggtcgggaa actggcgcga gggttcaaat ccctctgtct 293820
ccgccattat attggtctgg tagttcagtt ggttagaatg ccgccctgtc acggcggagg 293880
tcgcgggttc gagtcccgtc cagaccgcca attagattgt ttagtttcac tttggtgaaa 293940
ctttttttat aaaaacaaat cattatgatt tgtttttatt aatataagca tgcaaaattg 294000
caatcattgt tttagaatca aagatttcgc cattaactac tttgtgataa gcggtatcaa 294060
tatccatttt aattaattca attacttcat cttcatcaca ctctaaagga ttttcgactt 294120
tgtaaacatc atgagcttcg tatacataaa gccattcatc actataacca ggagttggta 294180
aaaacttaga aattaaactt atctttttag cactatagcc agtttcttct tctaattctc 294240
gtaaagcgca tatagcagta tcttcattta attctaattt acccgcagga atttctaaag 294300
tatctacagc attaggatac cgatattgct ttactaataa aattttgtca tcaacaatag 294360
caagaacgcc aactccgccg tggtgtcgaa ctacttctcg agttgcgaga ttcccatttt 294420
cacattctac tttgtcttta taaacagtga taatttttcc atcatagatt atttctgatg 294480
atattttctt ttccattagt ttcacctcat taaaagtata acaaaaaaag tatgcggggg 294540
tgcatacttt tttctattat ttcacgtaag ggtgataata gggggtatgt aaagcgaaat 294600
acttcactta acaaagtcaa ttatagcatc agtttcataa aatgtaaagg gttacaataa 294660
aagtattagg cgtttttagc aaattttgtt ataatgtttc aaggtgatat aatgaaaaaa 294720
ttaaaaataa cagaaaatga tgctaatcaa agaattgata aatatttaaa aaagttacta 294780
gttaatgctc caaataattt tatatataaa atgtttcgaa aaaaagatat caaagtaaat 294840
gggaaaaaag tggatgaaaa atatatttta tcattagatg atgaggtcga aatgttttta 294900
tatgatgata aattcaaaga atttacagaa accaaaagta tctatgaggt taataaaacg 294960
tttagtgttc tttatgaaga taaacatgta ttgattgttt ttaaaccagc agggctttta 295020
gttcatgagg atgcaaatga aagcattaat actttaacaa atcaggtttt aagttatctt 295080
gcttcaaaaa atgaactaga tctaagtcga gaaaatactt ttatgccagg accagttcat 295140
cgtttagaca ggaatactag tggaattgta atttttggta aaactttggc agctttgcaa 295200
aatctcaatg aaatgataaa gcaacgtcat tgcattgaaa aaaaatattt aacgatctgt 295260
cgcggacaat tgaatcatca gcgaaattta cacggatata tgatcaagtt agagaatcag 295320
gctcaagtta aattagtaaa gaaagactat cctggggctt taacgatgga aacgattgtt 295380
aggccgttaa aatataattg tgattatagt cttgttgagg ttacattaat aactggacgg 295440
atgcaccaga tcagagtaca tttatcaagt attgaacacc caattattgg tgatcgtaaa 295500
tatggagatt ttgaactgaa taaatatatt aagaagactt ttggtttaaa taatcaattg 295560
ctgcatgctt ataaaataaa atttgtaaaa acctttggtg tactaaatta tcttcaagat 295620
aaagagataa tttgccctgt gccggctttg tttgaaaaaa tagagaaaag tttgttatag 295680
acacctttaa ataaagagtt gtttattgta taattattta catagattat aggaggaaag 295740
atatgaaata ctatattgga attgatttag gtgggactaa tgttcgtact ttgctggtgg 295800
atgaaaatgg taaaacttat agtgaagtaa aagataatac tgaaagagaa aatggtcctg 295860
actatgtatg tgctaaaatc attcgtcaaa ttgaaagttt agatacatca atttgtggtg 295920
gtttacaagg tgtaagtgga attggtattg gggtacctgg acctgttgac acagtaaaag 295980
gtacaatgat catggcaaca aatttacctg gattcgaaaa ttatccaatt tgtgataaat 296040
tagcagatcg ttttaattta ccaactttta ttgataacga tgcaaatgtt gctggattag 296100
cagaagcttt attaggtgct ggaaaagatt atccgacatg ttattatgtg actatttcaa 296160
caggaattgg gggagccttt attgttgatg gtaaattagt ttctggtggt cgaggacatg 296220
ctggagaaat tgggaatatt attgttaaaa acaatggtta taaattcgga ggtttaaatc 296280
caggggctgc tgagggagaa actagtggta ctgcaattac tcgtaaaggt aaagaacttt 296340
taggagaaga tagagtaaat catgctggag atgtttttag attggctagc gaaggtgatt 296400
taaaagcaca aagtatagtt gatgaatgta tttcagaatt agcaacaatg tttgctaata 296460
ttgctcacac tgttgatccg cactgttttg taattggtgg tggtgtaatg aaatctcgtg 296520
aatatttcta tgatcgctta gtagaacaat ttaactcaaa aattcatgta ggaatgcgcg 296580
gatatattcc gttattagga acaaaattag aagattgtgg agcaatcgga gcagcaatgt 296640
taccaatgtc aagattaggt taagaaagga tatttcatcc tttttttttg atttaaagta 296700
gtagtttttt aaatcgaata atggtattat agtacggtga ggtgacgaga atgtcaaaaa 296760
gagtagtatt aggattaagt ggtggtgtcg attcagcagt tgctgcttat ttgttaaaag 296820
aacaaggata tgatgttatt ggtgtgttta tgcgtaattg ggatagccag ttaaataatg 296880
atattttagg taatcctact aatgataatg atatctgtcc acaagaagaa gattataatg 296940
atgccaaggc tgtagctgaa tgtcttggga ttcctattaa aagggtggat tttatcaaag 297000
agtattggga tcatgtattt acatactttt tagatgaata tcgaaaaggt agaacaccta 297060
accccgatat attatgtaat aagcatatta aatttaaagc ttttttagat tttgctaaaa 297120
ctttaaatgc agattatatt gctacaggtc actatgccca agttaaacat tatcaaggag 297180
cagattcggt gatgttaaaa ggccttgata ataataagga tcaaacatac tttctatgtc 297240
aattaaatca acaacagcta caaaactcat tatttccttt aggtgaaata gataaaacag 297300
aagttcgtcg aatcgctaga gaattgaact taccagtagc agataaaaaa gacagtaccg 297360
gaatttgttt tatcggagaa cgtgatttta aagagttttt acaaaattat attccagctc 297420
aagctggaaa aatggttgat atagaaactg ggaacgtgat tggtgatcat tcaggaatca 297480
tgtactatac tattggtcag cgtaaaggat tagggattgg tggtccaggt gatgcatggt 297540
ttgtcgttgg gaaagactat gataaaaatg tgttatatat ttgtcaagga gatcaaaaag 297600
attggttata ttcaaccggg gctctgatta ctgatgtgaa ctggattgct tcaactaaac 297660
caatagataa aattgcatgt aacgctaagt ttagatatcg tcagccagat aatccaattc 297720
aacttgaatt tattgatgaa gatactgttt acttaacttt tgataaacca ataaaagcgg 297780
tgactccagg ccaagctgca gtcttttacg atggtgatat ttgtcttggt ggtggaacga 297840
ttgaaactgt ctataaagat gggcagccaa tcaagtattt ataatgattg aatatacagg 297900
ttatattaag aagattcgtt tttatagcga atcttctaat tatatcgttg ctttaattga 297960
agttgagcag gaagataagt tgatcacaat gaatggttat atgaataatt ttaatgatta 298020
tgaaaaatat gcttttattg gtgattacga aattcatcct aaatatggta aacagtttaa 298080
attatcagaa tatcgtatca tttatgcaaa agaaagtgaa gaaattatta aatatttatc 298140
tagtccgcta tttaagggga ttggtaaagc tttggcaaca caaatagtaa atacacttgg 298200
tgaagagtgt cttgaaaaga ttaaagaaga taaacataat ttagatttgg ttagaggaat 298260
gactgaaaaa cggcgggaaa taatttatga agcattgact aatggtgatt atgatcaaga 298320
agtaatgcag ttttttatgg gacatggtat cagtctgaaa aacttgggct tgattcaagc 298380
atattatcaa gaaaaaacat tagaaatact tcaaaacaat ccgtaccaac tagtagagga 298440
tattgatggg attggattta aaacagctga tgagttagct ttaaaaacag gtgggacact 298500
tgataatcct aatcgaatta aagctgggat tatttacagt attaagcaat atgggtttaa 298560
tactgggagt acatactgtt accttgatga aatcaaaata atgttttcta aaataatata 298620
taatattgaa gaagtatcgt ttaatgaata tcttgatgaa ttgattgatg aaggattgat 298680
tattcaacgt ggtgataagt attattattt tgaaatggat gaggctgaaa aaaatatagc 298740
tgaatattta aaaatacgga taaataaacc cgatgaactt tttgatgaaa aagaagtaga 298800
acgattgttg acaaattatg aaaagactca aggtatatgt tatgctgcca agcagaaaga 298860
agccctaaat tattttttaa agtcttcttg catgattttg acaggcggac ctggaactgg 298920
gaaaacgaca attgttcaag cacttttaaa agtgtattcg gcattatacc cagatgatcg 298980
aattggttta gttgcgccaa ctggtcgggc tgcaaaacga ttgacagaat taactggaat 299040
ttatgcttgt acaattcatc gcctattaaa atgggatctt catagtaaca catttgctat 299100
gaataaaagc aatccattag atttagatgt tttgatcatt gatgagtttt caatggtcga 299160
ttgtttattg ttgagtaaac tttttgaggc gggtcgagga atcaataaag tattatttat 299220
cggtgattac catcaattgc cttcggttgc acctggaaat atattacagg atttgatgga 299280
agctggagtg aaaacgattg agctagatga aatcttcaga caagctaagg attcaggaat 299340
tattcaattg gctcatcata ttattcataa tgaaattgaa aatatggatc tttttgagca 299400
atatcgggat ataaactttt ttccttgcat aaactatgat gtcgtaaaaa atgttaagat 299460
aatagtaaaa aaagcaattg acgaaggtta tgacacaaat gatattcaag tactagtacc 299520
aatgtatcag ggagtggctg gaatcgatgc tttgaatgat gctttacaag atgtttttaa 299580
tccgattgat gaatttaatg attcatatca aattggccgc aaggaatatc gtgtaggtga 299640
caaaattttg cagttaaaaa atcgacctga tgatgatgtt tttaatggtg atattggaac 299700
gcttgttgaa atatgtcgaa aagataattt tgaatatttg caagatacac tgattgttga 299760
ttttgatggt aattttgttg aatatacaag taatactttt aacacaatta ctcatgctta 299820
ttgtatgtcg attcataaat cgcagggaaa tgaatttaaa atcgttatta tggcggtctt 299880
gtctgattat tatattatgc tacggcgtaa tctattatat acagcgatta caagagcaaa 299940
gcagtctctc tttattttag gaaactctaa agcttttatg catggtttag caaattatca 300000
agacagtcgt cgaaaaacaa gcttaaaaag tcgttttaaa acaattgaaa ccttaaatgt 300060
gtatgatttt cttgaataaa ggtaaactat actgaggtga gatatatgat gacaagaagc 300120
aaaatactaa ttggattaac agttgcatca ctaatgattt tgttgagtga atgtgagtgt 300180
gttgaagata tgatgtatga actcaaagca aagatgtaaa gatataaatt aatagtcttg 300240
aaaaatataa ttggatagtt tataatttgg taaatcgttg aaaaagaaaa gtactataaa 300300
atagatcttt cagagaaagt atggctggtg aaaatactta tcattttata ggaaagctac 300360
tttggagagt aattaaagat taccgtgtag gctacgttac cagtcaagta agggcatgag 300420
ttttcatgaa ctaggatggt accgcgatta aagtcgttcc tagcaatagg gcgacttttt 300480
atattgtaaa ggagaacaag atgaaacaat taacaggaaa tcaagttaga aaaatgtttt 300540
tggatttttt tgaaagcaaa ggtcataaag ttgaacctag ccactcatta attcctaatg 300600
acgatccaac tttattatgg atcaatgctg gagtagcagc aattaaaaaa tattttgatg 300660
gaacaataac tccagataat ccacgaatta caaatgctca aaagtcaatt cgtactaatg 300720
atattgaaaa cgttggaaaa acagctcgtc atcatacatt ttttgaaatg ttagggaact 300780
tctcaattgg tgattatttt aaaaaagatg caattgattt tgcgtgggaa ttattaactg 300840
atgaaaaatg gtttgctttt gaaaaagata aattatatat tacagttcat gatcatgatg 300900
aggaagctta tgactattgg gttaatgtca aaggtgttgc tgttgatcat atgttaaaaa 300960
caccaggtaa cttttgggaa attggcgagg gaccatgtgg acccgattca gagatttttt 301020
atgatcgtgg ggaaaaatat gatcctgatg gtttaggaac aaagttgttt tatgaagaat 301080
tagaaaatga tcgatatatt gaaatttgga atttagtatt ttcacaatat aactcacaag 301140
aaggagtagc tcgtgaagat tataaagagt tgccacaaaa aaatatcgat actgggatgg 301200
gattagaaag aattactagt attattcaag gtggagaaac aaattttgat actgattttt 301260
tcttaccaat tatccatgaa gtagaaaaat tagccaatgt ttcatatcaa gaaaataaga 301320
tggcttatcg agttattgct gatcatatcc ggactgtaac atttgcactt gctgatggag 301380
cattatttga taatgcaggt cgtggatatg ttttgaggag aattttaaga agagctgttc 301440
gttatggtaa gcaaattgga atcgaaaaag cgtttatgta tgatttagtt gatgttgtaa 301500
gcgaaattat gaaagaattc tatgattatc taccagaaaa agtaagttat attagtgact 301560
tagtaaaaaa agaggaagaa gcttttcata agacgttaac aaatggtgaa aaattattaa 301620
gtagtattat cgcaaaaaat actgatggtg tgattagtgg aaaggatgcc tttaaattat 301680
acgatactta tggttttcct tttgaattga ctttggaaat tgctgaagaa tcagatttaa 301740
aagttgatga agaggctttt agagcagagc ttaaagtaca acaagaaaga tcgcgtggag 301800
cacgtactga tagtgaaagt atggcaagtc agaaacctga tttaatggcc tttgatttac 301860
catcgaattt tgaatatgat ccaacaaata tcaatagtgt agttattgga ttatttaaag 301920
atggtgttaa aacagatcga attgatgatt atggagaagt catttttgat acaacaactt 301980
tttatgctga gatgggtggt caatgtgcag atactgggta tgtttataat gaaaattgtc 302040
agggtgaagt aattaatgtg ctaaaagcac caaatcaaca gcatttacat ttcgttaaat 302100
tgaagacagg aacgattcga gttggtgata ttttaacttt agatgttgat aaagctaagc 302160
gaaataagat tattgctaac catagtgcta ctcatattct tcaagcagct ttaaaagaaa 302220
ttattggaaa acatattaat caagctggtt cttatgttga tgatcatcgt ttaagatttg 302280
attttactca ttttgaaaaa ataacaaatg aacaacttaa attaattgag aatcaggtta 302340
ataatgtcat ttttgatgga gttgctgtgg atattgcaca catgactaaa gatgaagcca 302400
ttaatagtgg tgctatggcg ttgtttgatg agaagtatgg cgataaggtt cgggttgttt 302460
caatcggtga ttattcaatg gaattatgtg gtggatgtca tgtttcaaac agtgcaaata 302520
ttggattatt taaaattgag gctgaagaga gtgttggtag tggagtgcgt cgaattgagg 302580
cggttactgg aaagactgct tatcaagcgt tagttcaaga aaaagaaacg gttgatatta 302640
ttagtaatat tttaaaactt aaaaatcgta aagaagtagt tgcaaaagtt actgcattaa 302700
ctgaagaact ttccaacact aaaaaagaga ttgaaatatt aagcggacaa ttaaatgcgc 302760
taaatgcagc aagtaaagcc aatgatattc aagaaatcaa tggagttaaa gtgttgtttg 302820
tagaagaaat gattgatgct gctaaagcga aacaacttgc ctttgatttt agagataaaa 302880
ttgaagaagg aattgtaatt ttagtaacac aatttgagga caaatgttca tactttgtcg 302940
gggtgactaa aaattatgtt gcaactggat ataaagctgg tgatattatt aaaaaaatca 303000
atgcagttgt tgatggtcgc ggtggtggaa agccggattt tgctcaaggt ggctgcccaa 303060
ttaatgataa gatttccaac atcaagggag aacttaaaaa tttcttttaa tttctaagta 303120
attggtgtaa aataattcta taggcaaagc cttaaaggag gtcgaataat atgcaagact 303180
taacaaagac aaaagtattc agttctgaag atatgcgtcg tgagatgatt cgtcaaaatc 303240
ttaaaacagt aattgatgca ttaaatgaaa gaggctataa tgcagtacat caaattgcag 303300
gttatttaat ctctaatgat cctgcttata tttcaagtca taaaaatgct cgaaatataa 303360
tccagcaaat tgaacgtgat gaaattattg aagaattagt caaatcatat ttggagaagt 303420
aggatggaac ggatattagg gttggactta ggttcaagaa cctgtggtat tgcaatcagt 303480
gatactttag gcatgttagc tcatggaatt gagacttacc gttttcgaga tgatgattat 303540
gatagagccg caaagcacgt tgttgcttta attaatgaac atcagatcaa aacggttgta 303600
cttgggctac ctaaacatat gaatggtgat ttgggtgagc gtgcacaaat atcaatcatg 303660
tttaaagaaa tgttagaaaa agaagtaccg ggtctcaatg ttgttttaat tgatgagcga 303720
cttacaacta aagtagctca agatcaactt atctttgctg atgtttctcg aaagaaacgg 303780
aagcaggtaa ttgacaaaat ggctgcagta gcgattttac aaggctactt agatgcccaa 303840
tagaaaggaa tttaaatgga agcaaataaa atccaagtga tcgatgatca aggtaatgaa 303900
aaagaatttg aagtattatt tacttttaat aatgaggaat taggaaaaca atatgtgttg 303960
tattatgata caacagttga agaacctagt gtatttgcat caatctatga tgatgctgga 304020
caattattcc ctatagaaac accggaagaa tgggaaatgg ttgaagaagt tttccaaagt 304080
tttatggctg aaagtgaaga aggtcatgaa tgttgtggaa accatggaaa tggatgctgt 304140
catgataatg atgaagaaca tgaatgttgc ggtaatcatg gagactgtaa ctgcgataac 304200
taataaaagc taaattattt agcttttttc tcttaaacta gaaaaggtgg tatagaaatg 304260
gctttaatgg gattatttgg aaaaaaaaga gttactgaat cattttttgt caattcatat 304320
ggaaatgatc agacacgtgg tatttataca tttcaagtag atattgaaaa tggagaaata 304380
ctttataaaa agcattttaa aacaccctca gaccctgtct atagctttaa ttatgggcgc 304440
tttgtgtgtg ttacatataa aaatagaaca ggtacaagtg gtgatggtgg aatttgttca 304500
tatgcagcaa ctgctgatat tttagcatta gtatcgcgaa ttagtgataa aggtaaaaca 304560
tatatgcatg cttgtgctaa tggtgatcat gaaacagcag ataaattata tgctgttgat 304620
tattataacg gtgagatcat ggtggcaaaa attgataaga aaaaactagt tgcacctatt 304680
tttaattata aattggaagg acatagtatc gatccaaaac gtcaaaatca accacaccct 304740
cattttgtcg attttactcc ggatggaaaa cgtttaattg ttgttgactt aggattagat 304800
aaagtactgc tctttaaaat ggaagcaaag gagattattt tggatgaaga acattcattt 304860
gatttagaac caggatctgg acctaaaaag attatgttca accaggctgg aacaatagcg 304920
tatgttttaa atgaattatc taatacaatt tgtgtttaca aatataatga tttgaaattt 304980
gaattaattc aaaccatcga tacatatcca aaagatgaat atgatgagcc tagcttagct 305040
ggacaaatgc tttttagcga aaaagaggag cgtatttttg ttactaatcg tggtcatgat 305100
agtttagcat tatttttagt agatcaagaa acaggtttat tgacttataa agattttgtt 305160
gatacttcac caaatgctcg tgatattgca atctttaaag atcgttggat tgttgcagtt 305220
tgccaaaagg gtggagtagt tgaaagttat gaataccgcg atgagagagg cggaatgctt 305280
tttgaaacca aatactcata tctagtcagt gagccggttt gcattacaaa atttgagact 305340
atttattaga gatgattatt catctctttt tttggcataa tatactgacg aagcatgttt 305400
tattatcggt agataagttg aataagcgct aaaaatatca tataatggtt aagacggagg 305460
agaatatgaa aaaaactcag aaaattatta ttggagcaat tgctggaata acgattgttg 305520
tactagcttt agtgtttttt tatttcaatg gccaaggtgc tgtttcttct aaaagtgaag 305580
aggtagtagt tgaaatatct ggatcaacat cttcggtctt aaatcagctt gataaggcag 305640
gtctattaaa aagcaaaaca gttgctagta tctatacaaa gtttaatagt tatagtttta 305700
aagcgaatgt ttatgtttta aataaaaata tggatttaaa gaagattctt acaattttgg 305760
aaggagataa ggattatata tctgctgcta aaattacgat attagatgga taccgtatac 305820
ctgaatgtgc tcaacaagta gcaaagggat tagaaatcga tagtaccgag gtattagaga 305880
aatggacaaa taaagaatat ttgcaaactt tagtggaaaa atactggttt ttggatgaaa 305940
gtattttgag tgctgatatt atgttcccgt tagaagggta ttttggtcca gaaacatatg 306000
taattacttc aaagaagaca tcgattgaag atgttacaaa gatgatgctg gatcaaatgg 306060
atcgtaattt aagtacttat aaagacaaaa tcagtaattt tatgattagt ggtaataaag 306120
tatcgatgca tcaattttta tcattagcat cagttgtaca atgtgagtca tctggccaaa 306180
aagaagatca ggctaagata gccggtgtct ttatgaatcg tttggaaaaa ccaatgcgtc 306240
tgcaaagtga tgtaactgta aattatgcaa atcaaattaa aacggtagca gtaacgtata 306300
atcacttatc agtcgattct aaatataata catataagta tgaagggtta ccagtcggtc 306360
caatcagtac agtttcaaca aacattattg aagcatgtct gaattatcaa aagactgata 306420
atttgttctt ctttgctttg aaagacgggt cagtcatcta ttcaaaaaca tatgaagaac 306480
atcaacaagt agtaaaggaa aataaatggt attaaaatga gatattatga aaaaatagaa 306540
gctgatgctt tagcccgaaa tatacctgta atgcagcgtg aagggcttga atttatgatt 306600
gaaattttta aacatcataa ttgtcattgt tgtttagaga ttggtagtgc gattggatat 306660
tcagcaatga tgttggtaag taatattaat aattttaagg ttgaaacaat tgaattaaat 306720
gaggaacgat atttagaagc tgtaaaaaat attgaagaaa ataatttaaa aagtcaaatc 306780
attattcatc atggtgatgc tttatcattt gatttagagc atttgaaaat taaaaaatat 306840
gattgtttgt ttattgatgc agctaaagca caatatcaaa agttttttga aaaatatatg 306900
cctttagtgg cagacgaagg tatttgtatt gttgataatt tagattttca tggtatgatt 306960
tttgatattg ataatataaa gaatcgaaat acaaaacaac tggtaaaaaa aataaagcgt 307020
tttaaagatt ggatctttga taacgaactt tatgatgttg aatatcatca tgttggtgat 307080
ggtatttgtg tgataagaaa aagggtggca caatgaagtt agtattatct ttaaatagca 307140
aaaaatttat ttatgattat gtggatattg gtgttgaata ttttgtcgtt ggggcaaagt 307200
atttttcatg tcgtcaagca ttatcgcttg agtatgatga aatcgccaat ttaaaaaagg 307260
tcctaggtga taaaaaagta tgggttttag taaatgcact agttgaagaa aaatatatcg 307320
atttcttaga aaagcattta attagattga gtcaaattgg agttgatgga attttatttc 307380
aagattttgg tgttttacag atttgtaatg agcataattt tgattttgag atgatttatc 307440
atccagatac attaaatact aatcaagcaa ctttaaatta cttgggaact caaggtatta 307500
atggtgcttt tttggcacgg gagataccgc ttgaagaaaa aaaaataatt gctaaaaatg 307560
ttaatgttaa aacaatgatt caagttcatg gtgttgaata tatggcatat tcaaaaagaa 307620
agctattgac taattatttt aaggaaatca atcaggatat tccaattgga atatcagatg 307680
atctgacgat tcaggcaaat ggtgtaaatt atagttgtca tatttatgag gatcaatatg 307740
gatgtcatat tttgagtaaa cagcaaatgt gtggcttaga cataatgagt agttttcaag 307800
attttgatta cctctacata gaatctttat acgtcgatga attaaagtta gtagaaatcg 307860
ttaatttata tcaagatgct ttaatcagcg ttggaaatag aacttacgga aaagtcgcta 307920
aggaattaat atcgcaactt tatcaactgg atccaaatat cgaatatcat catagcttta 307980
tgtttgatgc aactgtttat aagattgatg atgtaagaaa gcgggaagaa aatgagaaat 308040
gtaagtaaag taattaacgg aaaaagggta ataataaaaa aacctgagtt attggcacca 308100
gctggtaact tagaaaagct aaaggttgcc attcaatatg gtgctgatgc agtttttgtg 308160
ggtggaaaag aattttcatt acgttctgga gcctcaaatt ttacacttga tgatattaaa 308220
gaggcagtaa cctttgctga tcagtatggc gctgcggttc atgtgacatg caatattatt 308280
ctacatcaag ataatcttga tgggattgaa gaatatctgc gggctcttga tcaagcaggt 308340
gttagagcga ttattgtggc tgatccatat attatgtcaa ttgctaaaaa gttgaattta 308400
aaattagaag ttcatgtttc aacacaatta tcaactttaa atacaaaagc aattaaattt 308460
tatcaaaatt taaaaatgga tcgagtagtg cttggtcggg aagtttgtta cgatgatttg 308520
aaaactattt tagataaaac tgatgtagat attgaatatt ttattcatgg tgccatgtgt 308580
attcattatt caggtcgttg catgttgtct aattattttt cacgtcgtga tgctaatcgg 308640
ggtggatgtt cacaatcatg tcgctggtac tatgatctat atcaaggtaa tcaaaaaatt 308700
aatcaagatg gtgtaattcc ttttagtatg tcaagtaagg atatggcatt aattaatcat 308760
attcctgaat tgattgaact aggagtcgat tcttttaaaa ttgagggtcg aatgaagtca 308820
ttgcattata ttgcaacaat tgtttcgacc tatcgaaaat taattgatga ttattgtaat 308880
gatcctgata attttgaatt gactgagaaa tattatcgtg aaatacaaaa agcggctaat 308940
cgttccttat gcactggttt ctttgatgat caggcgggta acgataagca gttatataat 309000
caacgtgatg aacatcctac acaagaattt tgtgcccgag taatcagcta tgatcaagtt 309060
aatcaaatag ctacaataga acaacgtaac tattttaaaa ttggtgatca aattgagttt 309120
tttagcccat atcacgaaaa tgttgttgtg ccagtaacaa aaattataaa tgctgataat 309180
gaagaagttg aagtagctaa tcatccaatg gagattctac aaataccggt cagtgttgaa 309240
ttacaaaagg atgatatggg aaggaaagtg atttgatgaa aaagccagtt attattggta 309300
ttgcgggagg tagtgcttcg ggaaaaacct ctattgcaca agagctttat gactgtttta 309360
aaggacgcca tacaattaga attattaaat tagatgacta ttataaagat caaacacatt 309420
tatcaatgga taaaagagtc ttaactaact atgatcaccc cttagctttt gatatggatt 309480
tattgattga acatcttgat ttattaaaag aagggaaaag tattcaaaaa ccgacttatg 309540
attttgaaca gcataatcgt agcaaaatag tagaaatagt tgattgtcgt gatgttttta 309600
ttcttgaagg gttatttgtg ttaaatgaag tacgaattag agaacgctgt gatattctag 309660
tatatgttga tacagatgca gatattcgct ttattcgtcg gttgagacgc gatcttgaag 309720
aacgagggcg gagtctagat tcggtatgta cacaatattt aacaacagta agaccaatgc 309780
acgaacaatt tgttgaacca tcgaaaaaat atgctcatat tataattccc gaaggaagca 309840
gcaacactgt agcaattgat ttattgttaa caaaaatatc ttcaatagtt gattagtgaa 309900
gatattagga ctagatattt atatagaatt atgctatatt agagactacg aggtgatatt 309960
atggaacacg aaaaagtatt gttaacccaa agtggggtag aaaaattaga acaagaaaga 310020
gataacttga ttaatgtcga aagacctaaa gttattgaag aattacaatt agcacgttct 310080
caaggtgact tatctgaaaa tgctgactac gatgctgcta gagaaaaaca agcacattta 310140
gaatcaagaa ttaaagaaat tgactatatg cttcaaaatg ctgaagttat ttctgaagaa 310200
caaatggatc taaaagtagt aaaacccggt actactgtaa caatcttaga tttatcagaa 310260
aaagatgctg aacctgaaag ttaccaaatc gttggatata ctgaaacaga ccctttaaat 310320
ggaaagattt caaatgaatc tccattagca aaagctgttt taggtcatgg agtaaatgaa 310380
attgtaacag ttggggttgc agatccttat gatgtaaaaa ttgttaacat tgagtttaaa 310440
aactagaact tataaaatga acctactatt tagactgcaa aataagtaag gttctttttt 310500
ataaacaatt ttaataagta gaaatagaaa aagaatgatt taatcagtat tttgtaagaa 310560
ctgtttaaat cattctttaa gggaaattat ctttggaaag atgaaatatt ctatggattt 310620
gtatataaag ttgattaact agatgattgg tatatgaggt aattaaagag attgccacct 310680
gtataataac attatcatta cggattgatt atgccaagat attaagcgtc taattttttt 310740
gtatataatt gtaaaattaa ggtagtgata attaaaatga ttggtcttga aaggatatta 310800
attagattaa tgtcttcaat atttaccatt aatgcgataa ttccaaagat caatccacat 310860
agtaaagcgt gaataattgc tttattttga aatattttga ttagccaaaa tgcccataca 310920
atcataatga ttccagcaat tatattaata atactatggt agataaaatt tgataaatga 310980
ataaaactta taattccggc catgataaga ctagtaatag taaaggtgat aaggataaat 311040
aaagcgaatt ttaggtatat ttttaaatat gatttcatat ttcctccttg ttatcttact 311100
aatattatat ttaaggattg gtgaaatatg aatatcttcg atgtattttt aattagtgtt 311160
tgcatttata tttatttaag tatcttgtta agaatttttg gtaaaaaaga atttagtcaa 311220
ttaaatgtat ttgattttgt agtattttta attattgccg agatcatgac agatacgata 311280
ggaaacagcg attttacttt ttatcatggt gtggttgcaa ctgttacatt gattgttgta 311340
gatcgacttg tttcaatgat aacaatgaaa tcaaaaaaac ttcgcgatat ttttgaagga 311400
cgacctacat acattatttt taaaggaaaa ttggatcaag aaataatgaa aaagcaacga 311460
tatactgttg atgatttatc acatcattta cgagttaatg atattgatag tatttctaaa 311520
gttgaatttg ctttattaga aacaaatggt tcactttcaa ttattcctaa agatcagtgt 311580
gtagtagaat taccggatgc tttaatctgt gatgggataa ttgatgaaga taatttaaaa 311640
ttgctcaacc gggatataaa ttggttaaaa aaagagttga aaaaacaagg tgtagataaa 311700
atagaagatg ttttttattg tgtgccagaa aagggccact tattagtaat aaaaaaatag 311760
agctggaatc agctctatcc taatagcatg cgatcgttgt caaattcact accgcttgct 311820
tcttcgaatt ttttaagtaa atcatcaact gttaatttgg ctttttcttc accgttgaca 311880
tcataaataa tacggccctt gtccatcata attaagcgat taccgatatt aatagcatct 311940
ttcatattat gtgttaccat taaagcagtt agcttttgtt cagtgacgat ttcctctgtt 312000
aaatcaagaa cttttttagc ggttcgagga tctaatgctg cagtatgctc atcaagtaaa 312060
agaattttgg gtttttgaag tgttgccatc agtaatgtta aagcttgacg ttgtcctcct 312120
gataacaaac caactttact tgacatcctt gtttctaaac ctaagtctaa acgttttagt 312180
gcttcatgat attgtttttt ttcttctttg ctgattcccc agcttaaacc acgacgttta 312240
ccacgacgaa aagccatagc cagattttct tgaatttcca tattagctgc tgttcccatc 312300
ataggatctt ggaaaacacg tccaataaat ttggcacgtt tatattcatc ggcgagcgag 312360
atgtcttgat tgtcaatagt aatatatcca cagtcaattg gataaacccc agcaatcata 312420
tttaaagtcg tacttttacc agccccgttt ccaccgatga ttgtaataaa atctccatca 312480
ttaatagtaa ggttcaaatc ttgaagagcc tttttttcat taacagtacc aaggttaaaa 312540
gttttactta catgttctaa tttaagcatt ctctttctcc tttgttaatt ttttgtatgt 312600
agcaatttgt tttcttttac ttaccataac aggtacagtt aatgctatac ctactaataa 312660
agctgtcaac agttttaaat catcagtact tagacccaat tgtaaaacaa ctgcaacaat 312720
aatacgatac aaaattgaac caacaataat agcagttaaa gtaaacatga aaccaggctt 312780
tcttcctagt attacttctc caataacgat tgaagctaaa ccaataacaa ttgctccaat 312840
tcccatctta atgtcggcat aaccttgaga ttgggttact aatgcaccag acattgctat 312900
taaaccatta gaaatcatta aacctaataa tttagttgta tttgtattag caccaagtgc 312960
tcgaaccata tgttcattat ttcctgtagc acggatagca ctaccaattt cggttccaaa 313020
gaaccagtaa catattaaaa taacgattat cgcacaaatt attccgatga ttaaagtaat 313080
ccatgcttgt gatagattga aagtatttga taaacctttg aagatagtat cactttgaag 313140
taaaggtgta ttactttttc ccatgattcg taaattaatt gaataaaggc cgatttgggt 313200
caagatacct gctaaaatcg caggtatttg acatttagtg tgtaatagac cagtaatagc 313260
tccggcaaca aatccagcaa ttatagctaa taaaacagca agaataggat ttattccatt 313320
gacaatagca acagcacaaa cagcaccgcc agtggcaaaa ctaccatcaa ctgttaaatc 313380
ggcaaaatct aataatctaa aagtgatgta gacccctaaa gccataattc cccaaaggat 313440
tccttgtgat gctgcacctt gaatagctaa gataaaactc attacttatt caccatcttt 313500
gctttagatt taagatcatc aggaattgta atgtttaatt ttttagcaac tttctcattt 313560
attgttaatt cacattcttc agcaggtaaa tattcaattg ccatatcagc aggtttagct 313620
tcgcccttta aaatttttac agcctgaaga ccagcacgat atcctagatt ataataatcg 313680
ataccataag tggctaatcc cccattttca accatcccac tttcaccaac aatacatggt 313740
aaattgtttt cattagcaac ttgagcaacg gttgccatac cttcggctaa gagattgtca 313800
gttggaatgt aaatagcatc tacttttcca attaatgact cagtaacttg ttgtatttga 313860
ttagaatcag taacagattt atcaactaca gttaaattac gtttagcaca ttcttcttta 313920
gcaatgtcag cttggaaaat tgagttatct tcggcattac aatacatgat cccgattgtt 313980
ttggcatcag gaagtaattg ttgtaacaaa tcaaattgat cagcaaccgg tgttaaatca 314040
cttgtaccag ttacatttcc gccaggtttt tcattggttt ttactaattt agcactagca 314100
ggatctgtta cagctgataa aacaattgga atttctgttg ttttgtttgc tgctgcttga 314160
gcagttggtg tagcaattgc gaaaatcaag tcaacgttat cgttaacaaa tttatcagca 314220
atggttgtac aatttgatcc atcaccttga gcattttggt catcaaatgc aacattgtcc 314280
tcaccatagc cattgtcttc taatgctttc aaaaatcctt ttttagcatt atctaatgcg 314340
ggatgttctg cgtattgaac aatgccaata ttaacatcct tacttccccc acaggcactt 314400
agagttagtg ccatcattac agttaaagat gcctttaata attttttcat atttattccc 314460
tccatatttt caattattaa acaaaaagtc gccctcgata gaggacgaca aagtcgcggt 314520
accaccccaa gtttattatt aactcacatt aataatcttc ataagtgtaa aactttacta 314580
cgataacggc tagccaccga tgattaccta cttatcagta tccgactcca tgatgaattc 314640
aatatttctt aacgtattgt tcgcaccaac cacaatatct ctgatatcta agtcatattt 314700
actacttcac ttcactgtct ttgtttaata gattgttacc taaaataata cgttatgaag 314760
ttctatttgt caatataata aaacttgtaa aattaggata aatagcttta tttctaaaaa 314820
agtatttttt gtttaggatt taaacaaatt aaattacttt aaatagtatt tatgataaaa 314880
gaatgtctaa agacatcata atgacaaaac caatcatgaa acttattgtt cccaaatcaa 314940
ttccttcagt tgcattagct tcaggaatta attcttcaat acagacaaaa aacatggcac 315000
cggctgcgaa acaaagagcg aatggtaaaa ctccattgac tagagtggca aaaataaagc 315060
ctaataatgc tgctgggatt tcaacaatag cagaaaattg tccatacatc atggcaataa 315120
aacggctttt tccgcattga tgcataggta aagaaatagc agtaccttca ggaaaatttt 315180
ggataccaat tcctagagct aagattaaag ctggtaagta atttccatcg tgacatcctg 315240
caaatgccac accaactgct aaaccttcag gaatattgtg taaggtcata gctaacatta 315300
atagcttgtt ttttgaaaag cgacctggat tgattccttc ttgttcatgt gacatcatgt 315360
gttcatgggg gagcagttta tcaatcaaca tcaataatgc tacaccacaa ataaaaccaa 315420
atggaatgat tagtaaatca agtttacctc cagcttcaag ctggtctttt gctggaagta 315480
ataatgaaaa aaatgaagca gcaaccataa ttccagcaga actgccaaga gcaatacaaa 315540
tgagtttttg actggctttg cgaacaaata gaactaacga tgctccaaag aaggtcatta 315600
accagttaaa tgttgctaca attaatacaa ttataaatgg atttaacgat aataaatatt 315660
ccattttttc acctcaatta ttactatgca taaaagccta ttgcatatgg gcatataagt 315720
tgctgatgaa gtaatattat gatatgatta ttcttaatga ggtggaacaa atggaagaaa 315780
tgtcaattgc gatgcaaaac tatttagaat taatttatga actttcatta gatggaaaaa 315840
aagctagagt cagtgatatc gctaagcatt taggtgtatc taaaccaagt gtcaataatg 315900
cagttgtggt tttggctaaa gatggctatg ttatatatga aaagtatgcg gatgtaaaac 315960
taacgcctaa agggaaagaa acggctgagt ttatctgtgg taaacatcaa acaattaaac 316020
aattatttgt tgaagttttg aacatagacg aaggaattgc tgataaagac gcttgtttaa 316080
ttgaacatgt gatttcaaat gagagtatta aagcaatgca agaattttta gatagacaaa 316140
aataatggtt attaggaagt ttcctaataa ccattattta atatccaaaa tccagatatt 316200
cttcagtagt aataattaaa atagctttat ttgtaatttc gtttttcttg ttgtcaaatg 316260
tttcaattgg ggtatattca actttatcac gacgttgaac atcttcatcg taaacataat 316320
cggcttgtct aaagaaaata ccatcttcat cataacgcga gatagtccca agaccacgct 316380
gattattata atgaacaact gttccttcaa cacgttctac atatttacct aaattattca 316440
ttactttttc atataattca tcatataatt cttctgatgt ttgatcgtta tatttttcac 316500
cataatcagc aactggagta tattcacgat tattttcagc agttaatttt gttaagaaag 316560
catctacaat ttcaattaac atcgggtctt cagtacgttg tgtagcctcc atcaagcgtg 316620
tataaattcc taaatgatta attgaatatc cattttcaaa aaattcatat agtaaataag 316680
catttgcttc tttaatgttg cctgtttgag cattagtttt ataaagaact tcgtagaaat 316740
taacattacg gattcggtta tgtaaagata agaatacttt tttagcttca tcgtattgtt 316800
ctagttcgac taatgaacac gctctttgat aattaatcca ttgcaatgta ttaaaatgcc 316860
attttaaaga tagagatagt gcattgttag cagtatcaac acattctttt gaacgtttgg 316920
cctcgtatag agcttttact tttaatcgat agtagcgttc ttttttagat tcaaattctt 316980
ttccttcatc attagtaaat ggtttatcat ctaatagatt aggatcaagt aaatcaagca 317040
tttcaactaa tttgttagga tcttcaggtt tttcacgttg taaatattta atagcacgat 317100
ttactgaagg ttccattgga gaataacgtt cctgtttgca tacagctaaa atatctttta 317160
agacactaaa gaaaagatct tcattatctc taattttttc atcatcaata ttgatgaact 317220
tattataaag tgcataccca tattgattca gatatccgcg aagatttgga cataatgaca 317280
taaatgtctt tccaacctca attgcctctt cattgttgtc gcttttcttc aatagtttaa 317340
tgtaatcatt ggcctgaaaa tcattgaagg aagttgggtc ttctttaaac ttttcattgt 317400
atacttctaa actttttaat tcattttcat tcataaaatc acctctaatc aatattatag 317460
catcttttta atctcttttg cagtagttaa gtaataaatt gttttgaaat gcaaatttat 317520
atgttataat ggctaggata atagatgagg tgaaagaatg aataaacaag tgtttagtat 317580
ggatttttat ggtaaaaatc taagtgtgga agtaggagaa ttagctaagc aggctaatgg 317640
agctgtattg gtaagatata atgatacagt tattttatca actgttgtgg cagggaaaga 317700
accaaaaaat gttgactttt ttccattgac agtaacttat gaagaaaaat tatattcagt 317760
tggaaagatt ccaggtggat ttttaaaaag agaagggcga cctagtgaac atgggacatt 317820
aacagctcga atgattgacc gtccaattag accattattt gcagatgggt ttagaaatga 317880
agtgcaaagt gttaacaccg ttttatctgt agatcaagat gcaactccag aaatggcggc 317940
tatgttaggt gcatcactgg ctttatgtgt ttctgatata ccttttaatg gccctattgc 318000
aggggtcaac gttggtttgg ttgatggtga attcattgtt aacggaacac cagaacagct 318060
agagaattct ttaataaatt tagaggtagc tggaaccaaa gatgctatca atatggttga 318120
agctgatgct aaagaagtta gtgaagaggt aatgttggaa gcattattgt ttggtcatga 318180
aaaaatcaaa gaattaattg ctttccaaga aaaagtagtt gaggcttgtg gaaaagaaaa 318240
aattgaaatt ccattatttg aattaaataa tgatttagtt gaagaagttg cagtacgtgc 318300
taaagccgaa atggctgcag cagtttcaat tcccggtaaa ttagagagat atggagcaat 318360
tgatgatcta atcgctcaag tgacagagga atatgacaat agagaatatg aaaatgaaga 318420
aataaaagct gatgtgatga aacaagttgg aatcatttta catgatctag aaaaagatga 318480
agtacgtcga ttaattactg aagataaaat aagaccggat ggacgcaaaa tcgatgaaat 318540
caggccatta gattcgcaaa ttgatttgtt acctcgagtt catgggtcag cgttatttac 318600
acgtggtgaa acgcaagttt tatcggttgc aacattaggt gcaattggag aacatcaaaa 318660
aatagatgga ttagggttag aagatcaaaa acgttttatg catcattata atttcccgcc 318720
atattcagtt ggagaaacag gacgaatggg tgctccaggt cgtcgtgaaa ttgggcatgg 318780
cgctttaggc gaaagagctt tagcacaagt gattcctagt gaagaagctt ttccttatac 318840
aattagagtg gtttctgaag tattggaatc taatggttcc tcttcacagg cttctatctg 318900
tgcttcgaca atggccttaa tggcagccgg tgttccaatt aaggcaccag tagctggagt 318960
agctatggga ctagtaaaaa aaggggatgc atatactatc ttgacagata tccaaggaat 319020
ggaagatcat ttaggagata tggattttaa agttgcagga actgatgcgg gtatttgtgc 319080
attacaaatg gatattaaga ttgatggtat tacgaaagaa attttacaag aggctttagc 319140
tcaagctaaa gtagctcgta aacaaattat ggcaaatatg atggatgcga ttgcagcacc 319200
acgtgatgaa ttatcaccat atgcaccaaa agtacaaatg atgaagattg aaccggatca 319260
aatcaaagcg gttattggtc aggggggtaa aacaatcaat gaaatcattg aacaatctga 319320
tggtgttaag atcgacattg aacaagatgg tacagttgtt atttatcatt atgatcaagc 319380
tgcaatcaat aaagcagttg agctaattga aaaaattgtt aaaaaagcgc aagttggcga 319440
agtttatgat ggtaaagtag taagagtaga agataattat gcttttatta atttgtttga 319500
cggaacagat ggttttttgc atatctctga ttatgcatat gaaagaacta aaaaaatggg 319560
tgaagtgata aaattaggtg atatcattaa agttaaagtc actaaagttg atgataaggg 319620
aaaagtaaat gtttcacgca aggctttact tcctaaacca atcaaaaaag aggaacctaa 319680
agaggaacct aaagaggaac caaaggcaga ataatgaaaa ggcttgttct tgctagtagt 319740
tcacctagaa gaaaagaatt attagaatta cataagtttg attttataat cgactttcaa 319800
gaaattgagg aagtgctaga tgaaagtttg gcacttcctt tacgtttaga gaagttagct 319860
tatcaaaaag cagcacccat tgctttaaaa taccctagtg atattgttat tggagcagat 319920
actatggtat gtttagaaaa tcagatgctg ggaaaagctg ctgatcgtca ggcagcttat 319980
gaaatgttaa aattgttatc tgatcagacc caaactgttt actcagcggt agcaatcatt 320040
gataatggaa aagtttctac ttaccatgat ggaactaaag tcacttttaa aaaattatct 320100
gatgaagaaa ttaacgctta tcttgattta aacgaatggc caggtaaagc aggagcttat 320160
gcaattcaag gtgaaggtaa ggcattagtc gctaaagtag aaggaaactt agagactgtt 320220
attggaatgc cagtttggat cattgaagaa tatttaaata atcatagata aaaaatattg 320280
agtgactaga ataaaaaagt atgatttcta ttatctggaa atcatacttt tttgtgatgt 320340
tatgtaatcg gttagattta ttttattttg gtaagctgtt aggatattgt cgggatctac 320400
aatattggga attttctctg ttaaaatatg tccaatcagc tgactgtcat tattaaatgt 320460
ttcaggtccc aataaaaaat aagtttcacc atcactaaaa taaagtgtga tatctacttc 320520
atacatatca gtgcttgggc ctccagtacc taaactataa agagggataa aacgctgtct 320580
agtttgaacg acaagttttt caatatcttg gtagaaataa aacttttgat atttataatg 320640
ctgattaatc aaggcagaaa gtacatattt aaaatggtga aaagaatttt tacgcttgaa 320700
aattcttatt ccttcttcta aaaattcaat agattggttt cttgatttat cgtaaagatg 320760
catcataaat tggaagttag caaaaataaa aattaaaata tttattaaaa agacgactgc 320820
gacaaaatat aaattttcta aataatacca tttttcgctc caaatccaaa tataaatacc 320880
gtaagtaaaa atcgaagcaa taattcctgc agaaatgacc tgtcgtattg ccatggctct 320940
agttagtggg cgattataag ctattgtttt acttgttttt cgatatccaa gccctttttt 321000
ctctggaact aatttaatat tttctaatgc aggaattagt ggaatatgca tatctttgaa 321060
tgttgatatt gtattttgaa gatcttctaa ttcagaaatt gtttgatcaa tgttgcgctt 321120
atgaatcttt aaacagtcat ctaaactgca tttattattt aagattgctt tgatatcatc 321180
aattgaaata tctaaattac gtaaaaattt cacaagtttt aacgtttgta aatcgtcatg 321240
gctgtagtta cggtaaccat tatttgttct tttgggtcgg atgattccca ctttttcata 321300
ataaagtatg gcatgtttag ttaaacctgt gattttttca acttcatttg ttctcatgga 321360
gacccctcct ataaagatat tataacgtaa agtagatatt tttgttttta taataataat 321420
ttaattattt attgaatctt taaaagtaat gtagtcatct ttataataaa tagatgttgt 321480
ttatttaagg cagaagttaa tattttttat aatattttgt tgaattttat aaatattgcg 321540
tattttatgt aaacggtaac atttttattg agttttatta taaaaaatca tataataaag 321600
tttatggagg gatgtttatg gcagacgtaa aaagaatcgc attattatct ggaggcggag 321660
attgccccgg gttaaatgct gttattagag cagtaaccaa agcggctatt aatgaatacg 321720
ggtatgaagt tattggctat gtttatggtt atcgtggtct ttataacaat gattacatag 321780
aattgacagt tgataaggta gagaatattt ataaagaagg tggaactatt ttatatagtt 321840
ctaataaaga taacttattc gactatcttg ttgatgatgg tcatggcgga aaggtaaaaa 321900
aagacgtttc tgatgttggt gtcgaaaact taaaaaaagc tggtgtcgat gtgctggttg 321960
ttttaggtgg tgatggtact ttaacaagtg ctcgtgattt ttcaagaaaa ggcgttaatg 322020
taattggtat ccctaaaaca atggataatg atttgccagc gactgattta acttatggat 322080
ttatcagtgc ttcttcagta ggaactgaat ttattgaccg gttaaataca acggcaaaat 322140
cacatcatcg agttatctgt tgtgagctga tgggacgaga tgctggatgg attgcgttat 322200
attcaggaat ggcaggaaat gcctcatgta tcttaattcc tgagattcca tttacaattg 322260
ataacattgt taagcacgtt gcaaaacgcg acgctgaagg ttatccatac actgtaattg 322320
cagtagcaga aggtgctaaa tatgctgatg ggactaaggt gattggaaaa atcgttgaag 322380
atagtcctga tccagttcgt tattcaggat tagctgcaaa ggtagctgat gatcttgaac 322440
aggcaattgc taaccatgaa gttcgttcag ttaatccagg acatatcatc cgtggaggag 322500
atatccaagc atatgatcgt attttatcaa ttcgttttgg tgtaaaagca cttgagctga 322560
ttaaagaagg taaatttggt aatgttgtta ctttaaaagg tgaagaaatg tcttatacat 322620
ctttagagga agtaatcggt gatgctaaat ttggaaaaca aaaacatgta gatcctaatg 322680
gtgaattagt aaaagctgca aaagcgattg gaatttgctt tggtgatgaa taagactgta 322740
aaacagtctt attttttata aaaatgtaaa taatattata tgaataaaaa ctattaagat 322800
tattttatta cataaaaaga atcaaagata gtcgaaatga ataattatta ttgcggtaga 322860
tattagtcta gtataagaag taccatttga taatattttt ttaaaaattt tgaattaaat 322920
attaaaaata gtacataata ttattgaggt gaatttatga aaaaaccaaa acatgggcaa 322980
cagtcaagta atgacaatgc taaagatcaa ttaggtgatg atgaaatagt tgtatcagga 323040
aatcaagaag attctacaat taaatataga taagggaaac taactttagt ttcctatttt 323100
tttacataat tgaacgattt tatccttaac tatagtttgc tatatttttt tcaggaggtt 323160
aagatatgtt aaaaaatgca tttctaagta ttaaaaagaa tattggcaag acagttttat 323220
tatttgtaat aatgacagta attgcgaact tgattattgc aggtttgtca atccagagtg 323280
cttcgaaaaa atcaatggag caaattagaa catcacttgg caatgatgta acattgacaa 323340
caaatatgca aaatatgatg ggtcaacgtg aaaaagggca agcagttagt gaagtagcag 323400
caagtgttac aattgcgatg gctgaccagt taaaagattt aaaatatgta aaaaattata 323460
attatgctat ttcaaccaca gcaagtagcg atgatattac agctgttgaa ttgaccacaa 323520
gtcaagataa tcaaacaatg gaacgtcctg atggacaaga aaatttccaa tcagcaaatc 323580
aaggagattt ttcaatcagt gcaaatacga cgatggaata tttagatagt ttcacagaag 323640
aaagtagtac tctaaaacag ggacgattat tatcaagtga tgatgccgga acaaataatt 323700
gtgtcattga aacaaattta gctactgata atgatttaaa tgtaggtgat acatttacag 323760
tttatactac tataaatgaa gaaacagtaa cacaacaatt aactattgtc ggaatctacg 323820
aggtgacaga tgctaaaaca atgggtggac cagggcaaag taatccgttt aatacaattt 323880
atacagattt atctattggt caaacattat cggggagtga aacaaatatt acatcggcaa 323940
cttattattt agatgaccct gagaatattg aagcttttca aaccttagca caaaaaaaga 324000
gtgatatcga ttttgagaca tatacgcttg atgcaaatga tcgtttatat cagcaaaatg 324060
taagtagttt agaaaatact caatcatttg caacaatgtt tttaatcgtt gtaattggtg 324120
ccggaagtgc tattctatgc ttgattttaa ttttaacaat cagaagcaga tattatgaaa 324180
ttggtgtatt tttatcatta ggacaaagta aagtgaaaat tattttacaa caattatttg 324240
agatgctttt gattgcgact gttgcctttg ttatttcact aggtaccgga aagttagtat 324300
caaatgtagt tggaaatatg ctagaatctg gaacgaacaa taatcaagtt caaatgcaga 324360
tgccggaaat cagagatcaa aataacgata gcaataacac tgattcgaca tccggtaatg 324420
ataaaatgtt cgatcaagca tttaatggac cggaaaatac agaattagat gtgtctttaa 324480
caactactac agtaatgcaa ttagcgggga ttacaattgc aatttgtctt gtttcaatcg 324540
ctattccatc tgcttatgta ttacgattat caccacgtga gattcttgtg aagaaggagg 324600
ggtagagatg gaaacaattt tgaattttga agatgtttca taccattatt tagatggttc 324660
tagtaatgta agtattttga ataaagctaa ttatagtttt gaaaaaggaa aaatctatgc 324720
aattgttggc gctagcggta gcgggaagac aacaactatt gtattggctg gtggtttaga 324780
taagccaaaa ggtggaaaag ttatttttaa aggccaagat actgcaagga ttggattaaa 324840
taaatatcgt cggaatgaca tttcgattgt gtttcaatca tataatttga ttcattatat 324900
gaatgcttat gaaaatgttg ctaatgcaat tgaaatagct ggacggaagg tccaaaataa 324960
aaaagaatat tgcctggata ttttaaaaaa attagggctt tcaaaagaac aaagtttacg 325020
agatattcgc aaactttctg gaggacagca acaaagaatt gctattgctc gtgcaattgc 325080
caaagatgtt gatttaattt tagctgatga acctacgggt aatcttgatg aaaagaattc 325140
taaagaaatt ttaaaaacat ttatcgattt agctcatcaa gctaataaat gtattataat 325200
tgttactcat tcgccatcat tggctcaaaa gtgtgatgtt caattaaaaa tagaggacgg 325260
acaaattgtt gaaatttaaa aggctgctca aacagccttt taatcattga tgggactttt 325320
ataaggatga cggtgatcaa ataatttatc acgattaatt ttttcattaa tataatgatc 325380
ataattcaat ctaaagatac atgaaaaaat caaatcaagc aaataagaaa tcgatgtttt 325440
ggatgaataa ggagctatct tagaaaatat cttttctcgt gatcctgtat tcataatata 325500
agtgcaatat tttgataatt gattatcccc gatagaagta atacccaaaa ggggaacatg 325560
catctttttt aaaaatttcg caagttctac catttcattc gtttcgccgg aatatgatat 325620
aagaatggct acatcatcag gactacaagt atatgataag aaaccttgct caccagcatg 325680
agctcgcatt tccaccattt taccaattcg catcattttg tgttgaaaat caaaaccagc 325740
taataaagaa ttaccatttc caaaaagata gatgcgtctt gcttgatcga gtaaattaat 325800
aattttgtca aggttcttaa aatcaactaa gtttaaggtg tcttcaatag cttcttgatg 325860
cagattggca atccgatatg caatttggct atttgagtcg gtgtttccaa aaggaaagtt 325920
gacgtcaaca cgttttttgt tttttttatc aaactgtaat tcagctgaat atttgatttt 325980
aaagtcacca tagccattaa gtcctaattt acggcaaaga cgaacaattg ttgctggaga 326040
agtataagtt tgtttagcta attcttttac tgataaatta agaatatctt caccattatc 326100
taatatgtat ttcgcaattg ttttttcaga actggagaaa tctaattcaa attctaattg 326160
agtcataata ctcataaaat cacctctatt tagtatatca tgaaacattg tttcataaaa 326220
ctggtattta ttaaataaaa tatgaaactt gattataagg tcagaaaaac tcatttactt 326280
atctttacag attaactaaa atggtatgtg aaagagaggt attgtaatgg aaaagaaatt 326340
accagataat ttttattggg gtggctcagt atcaagtttt caaactgaag gagctcgtaa 326400
cgaaggtgga aaaggcgttt gtatttatga cgttagacca actgatccag aattttctga 326460
ctggtcagta ggaattgatg aatatcatcg ttatgatgaa gatattgctt taatgaaaga 326520
tatgggattc aatttttacc gtttttcaat ttgctggtca agaattattc ctgatgggac 326580
tttagatgaa ccggtaaatg aagaaggaat taaattttac agtgatctaa ttgataaatt 326640
gattgctgct ggtatagaac ctatgataac tttagtgcat tttgatatgc cttataaatt 326700
agtaaaagaa cataatggtt ttgcatcacg ctatgttgtt gactgttttg aaagatatgc 326760
tcgtgtatgt atcgaacgat ttggtaatcg agttaaacac tggatgtctt ttaatgaaca 326820
aaatttacat gggatgatgt tgcgtgtatc taacgctgaa gaaattcctg aaggtgtgga 326880
cccagctaaa catttatatc aagtcaatca caatgttttt attgctcatt gtaaagctgt 326940
caaagcatta agagaattac agccagatgc tcaattctgc ggtatgaatg cagttactaa 327000
tatttatcca tattcaaata cgccaaagaa caatttattt gcatggaaag cttatcaata 327060
tatgaatggt ttccactgtg atgtttttgc taaaggaaaa tatccagatt atatgatagc 327120
atatttagaa aaccgtggat ggatgccaac atttgaagaa ggcgatgatg aattattaaa 327180
gtatactgta gattatattg cttttagtta ttatcgctct aatactgtta ctgaaggtga 327240
atttgattat acaagaccat atcatgaagt agttggagaa catacagtta aaaatccaca 327300
ttgcgaagct aatgaatggg gttgggaaat tgatcctgtt ggttttagat ggactttaaa 327360
tgatttagca acacgttctg atttaccggt tttcgttctt gaaaacggaa ttggatggcg 327420
tgaagatatg acgcaagaag aagttgatac aatgttagca gctaataaaa caatcgaaga 327480
tgattatcgt attaattatc atcgtgatca cataaaagaa atgaaaaatg caatgtttga 327540
agaaggcgtt aaatgtctag gttacattac ttggggacca attgatattc tagcaagtat 327600
gtgtaatatg gataaacgat atggttttgt ttatgtaaac cgtactaata aggatattcg 327660
tgatttaaaa cgtattccta aaaaatcata tcattgggtt aaaaaagcat ttgaatcaaa 327720
tggagaagat ttagactaag aaggagaaat ccttcttttt ttgctgataa agttaaaata 327780
tcctaacttt tttcttggca actattgact tttaagttag gcaggtataa cataacagta 327840
gttagatagg actaacaaga aaaagcgagg aagtgatgat gatgccttta actatggcga 327900
caattggtga agtacagacc ataaaaaaag tcggaggaaa acaagaagta aaattatttc 327960
ttgaatcgct aggctttaca acaggagcga cagttactat tgtaagtaag aaccaaggaa 328020
atctaattac taaaattaaa gaatcaagag tagcgattag tcaagagatg gctaataaaa 328080
ttatgattta actattaaaa gggggataat taattgaaaa cgctaagaga tgtaaaatgc 328140
ggaactagtg cgagagtcat gaaactgcat ggagatggag ctgtaaaaag aagaatcatg 328200
gatatgggaa ttactaaggg gacagaagta ctagttcgta aagttgcacc attaggtgat 328260
ccaattgagg ttaaagtacg aggatatgaa ctatctttgc gtaaagccga tgcagcaatg 328320
attgaagtat tatagtagta aaatatatag gagggtgaaa aaatgtcaat tacaattgca 328380
ttagcgggga atcctaatag tgggaaaaca acgctattta atgctttgac tggttccaat 328440
caatttgttg gaaactggcc aggggtaaca gtagagaaaa aagagggtaa attaaaaggt 328500
cataaagatg ttaaattaat ggatctacct ggtatttatt ctttgtcgcc atatactttg 328560
gaagaggtag tggcacgtaa ctatctaatt caagaaagac cagatgcaat tatcaatatt 328620
gttgatggaa caaacttaga aagaaatctt tatttaacta cacaaattat ggagttgggg 328680
attcctgtta ttatggcaat caatatgatg gatatcgttg ctaaaaataa tgataagatt 328740
gatgtaaaaa aattatcaaa agaattgggg tgccaagttg ttgaaatttc tgctcttaaa 328800
ggaaaaggaa taaaagaagc ggctgatcgt gctgttactt tagctaattc taaaagaata 328860
aatgcaccaa ttcataaatt tgatagtgct gttgaagaaa aattagacca gattgaagca 328920
atgttgccaa gtgatattgc agtggaacaa cgacgttttt atgcgattaa attatttgaa 328980
cgtgatgata aaatttcagg attaatgagt agtgtaccta atgttgaaac aattattgat 329040
caaagtgaaa aagaattaga tgacgatgca gaaagtatta ttactaatga acgttatcaa 329100
tttataactt ctattataga tgattgttat aaaaaacata gtcatgatca attatcagtt 329160
tctgataaaa ttgaccgcat tgttacaaac cgctggttag ccttaccaat ctttgcagta 329220
gtaatgtttg tggtttatta tatttcagta actactgttg gtacttgggc gactgattgg 329280
gcaaatgaag gtgtgtttgg tgatggatgg agtttatttg gactagcagt tccatcaatt 329340
ccaagcttaa ttgaaggatt attagaatca ttaggaactg cggcctggtt aaatggctta 329400
attttagatg gtatcgtagc tggggtaggt gcggtattag gtttcgttcc acaaatgtta 329460
gtgttattct ttttcttagc ggtgcttgaa tcatgtggat acatggctcg ggttgcattt 329520
attatggata gaatttttag aaaatttgga ttatcaggta aatcattcat tccaatgttg 329580
attggaactg gatgtggggt accaggaatt atggcatcac gtactattga aaatgatcgt 329640
gatcgaaaaa tgacgattat tacaactacg tttattcctt gtggtgctaa gttaccaatt 329700
attgcgttaa ttgcaggtgc attatttggt ggtgcatctt gggtagcacc gagtgcatat 329760
tttattggaa tagctgcaat tattacttct ggaattattt taaagaaaac aagacgtttt 329820
gctggtgaac cagcaccatt cgtaatggag ttaccagcgt atcatatgcc gacgattact 329880
aacgttttaa gaagtatgtg ggaaagagga tggtctttca ttaaaaaagc tggaacgatt 329940
atcttattat caagtatttt agtttggttt acttcatact ttggatttgt cgatggacaa 330000
tttacaatgt tagaagatac tcagttagat catagtattt tagcatcaat tggtaatgca 330060
attgcatgga tatttacacc acttggttgg ggtgattgga aagctgcagt agctgcgatt 330120
acaggtttag ttgctaaaga aaacgttgtt ggtacattcg gtattttata tggatttgca 330180
gaggttgctg acgatggagc agaaatctgg ggaaccttag cagcaagcta tacacaaatt 330240
gcagcatttt cattcttaat ctttaactta ttatgtgcac catgttttgc tgctatggga 330300
gcaattaaaa gagaaatgaa taatggccgc tggacagcgt ttgcaattgt gtatcaaact 330360
gtatttgctt atttagtagc atttagtgtt taccaaattg gaaatttagt tattactgga 330420
acatttacat ttgctacagt aattgctata ttagtagtga ttggttttgt ttatctatta 330480
gttcgaccat ataaagaaga caatcgttta aatatcgatt taaataaaac tgtaactgaa 330540
aaatagaaag ggtgataaca gtgaactggc taattgaaaa tttatcgact atcatcgtta 330600
gtgtcatttt attatttgca gtcctattag caatcaattc aatcagaaaa gataaagcta 330660
atggtaaatc tagttgtggc ggaaattgtg gtagttgtgg tactagttgt catagccgca 330720
ctaatagttt agtagatagt tatcatcatg atcacgggaa gtgttagtac ttcccttttt 330780
ctttttttgt aaaaagaata caaatattct ttaaaatagg tatacttata taataaataa 330840
tcttaaggag gaatgttatg gagaaaaaag caattttttt agatgttgat ggaacattgg 330900
ttgctaatca tggcaaaatg actgagcagg taaaaaaagc aatcactcta gcccgtaatc 330960
agggacataa agtatttatt tgtacaggaa gaaataagat aggaattaga aatgagttag 331020
aggaagtaaa ttttgatggt tttattgcta gtgctggaag ctatatcgaa gttgctgatg 331080
aagtagtcca tagccgttat tatgatcgta aattaattga aaaagcttgc gatgtattta 331140
atcgtaataa tatcgtatat aattatgagt gtaccgatat tacatatatg tcacccaaaa 331200
tgatggaatt ttttgtaggt ggaaataatg aggaagcgac taattcggag atggaacgct 331260
taaaagctga acaaagtgat aaatttaatg taagagatat gaatgaatac gatggtcgtg 331320
gaattcataa aatatccttt attgcaatga agcaggaaga tttcgatcat gcttttaaag 331380
aattgaaaga gaactttaac tttgtagtac atgatatgtt tggcagtaaa aatattaatg 331440
gtgaaataat gtcaaaactt gataataaag gaacaggaat caaacgaatt gttgattatc 331500
taaatataga tatggaagac acaattggat ttggtgatag tatgaatgat tatgaaatga 331560
tcgatgcagt caaatgtgga gtggtcatgg acaatggcag tgctcggctt aaggaaatag 331620
ctgatcgaat ttgtaaaagt gttgatgaag acggagtcta ttatgaattt attgatttag 331680
gaataattta agttaaaaag attataaaat ataaattgaa atattattct gatattggtt 331740
gacttcttat tgttgctgtg atattatata tgagtaacga gcaatgaata tttaacttac 331800
agatgtgaaa gttgtattta taagcaactt agcatctgct ttttttatag taatgctttt 331860
tataataaaa ataggaggta cgtctgatga atacaggtac agtaaaatgg tttaatagtg 331920
aaaaaggttt tggatttatt acaaaagata caggtggaga tttatttgtt cacttttctg 331980
caatccaagg tagtggattc aaatctttag aagagggtgc taaagtaagc ttcgatatcg 332040
ttgaatctga tcgtggtgaa caagcagcaa acgttgcagc tttataatta accaaaagtc 332100
tcaatagaga ctttttattt ttgactaatt tagcactttc ctattgacac tgctaaatag 332160
ttgtattaga atatctttag cacaaatgaa tgaggagtgc taatatttag aatggagatg 332220
tgagtatggc tgagaaaaaa caatttaaag cagaatcaaa aagattatta gatttaatga 332280
ttaattctat ttatacacat aaagaaattt tcttacgtga attgatttct aatgcaagtg 332340
atgcaagtga taaattatat tataaagcac ttacagaaaa tatttcttca attaatcgca 332400
atgatttaaa aattatgatt gaaatcgata aagaaaatcg tgttttaact attaaagata 332460
atggaattgg gatggataaa gatgaattag aaacacatct tggaactatt gctaatagtg 332520
gttcatttga gtttaaaaat gaaaatgaac atgatgatat tgatattatc ggacaatttg 332580
gtgttggttt ctatgcagct ttcatggtgg caaaaaaagt agaagtgatt tctaaaaaat 332640
atggaactga gcaaggatat acttgggtat ctgaagttag tgatggctat gagatttttg 332700
aaactaatgt tgctgatcat ggaactacaa ttaaattata cttaaaagat aatacggatg 332760
atgataacta tgatgaatat ttaaatcaat atcatattcg tgatttagtt aaaaaatatt 332820
ctgattacgt gcattatcca attaatatgg atatgacagt ttcaaagaaa aaagatgata 332880
gtgatgaata cgaagatgtt attgaaaatc aaacattaaa ttcaatggta ccattatgga 332940
aacgtaataa aaaagatatt actgatgaag aatataatga tttctacaaa gataaattta 333000
atgattttaa tgatccgttg aaagtgattc atagccgagt agaaggtaac gtttcatatg 333060
attcattatt atttattcct tcaaaaccac caatgaatta ttattcaaat gaatatgaaa 333120
aagggttaca attatattca cgtggtgtct tcatcatgga taaagctagt gaattagttc 333180
ctgaacattt ccgctttgtt aaaggattgg ttgattcaga agacttatca ttaaatattt 333240
caagagaaat gttacaacac gaccgtcaat taaaagtaat tgctgataaa attgaaaaga 333300
aaattcaatc agaattagaa acaatgttga aaaaagatcg tgtaaaatat gaagaattct 333360
ttaatagttt tggtttacaa ttaaagtttg gtatttataa tagctatgga atgttaaaag 333420
aaaaattaca agatctgcta ttatattatt ctagtaaaga agaaaaactt attaccttag 333480
cggaatatat tgaacatatg cctgaaggtc aaaaggagat ttattttgca agtggtgaaa 333540
ctcgtgaaaa gattgccact ttaccacaag tagaagtagt caaagacaaa ggatatgatg 333600
ttctatattt aacagataat gtagatgaat tctgtttcca aatgatgcgt gattataagg 333660
aaaaaccatt taagagtgta gctcaaggtg atttagatat cgatagtgaa gaggaaaaga 333720
aagaattaga aaaaactaat gaagagaata aagacttatt gacagcaatc aaagattctc 333780
ttggtgataa agtcgttgac gtaaaagtat cttcacgatt aaaatcacat cctgtttgtc 333840
tagtttctag tgatggagta tcatttgaaa tggaaaaagt cttaaatcag atgcctgaag 333900
gtcaagaagt aaaagcaggt agaattttag aaattaatcc taatcatgat attttcaatg 333960
ctatgaaaaa ggtttatgaa aataatcctg ataaagtaaa tgattatgca agtatcttat 334020
atgatcaagc tttattgatt gaaggattct caatcgacaa tccagttgat ttttcaaata 334080
aaatttgtga tttgatgatt gaattgaata aataattgaa gaattttaaa gggtagatgt 334140
taagtctacc tttttttgta ctatttagta aaaaaattac taaatacatt aaaaaattga 334200
gcgattatgt gtataataga catatatgaa aatagagtga gagggtatat atgttaaata 334260
tttgtgggat tattgctttt tttatgatgt acatttatga tttgaattta atttatttag 334320
gtaataaaat ttttaaaaag ttttttgcga ttgggtcaat aatattagta tttgctactt 334380
tagcgaatat tattatttat tttcctaaaa aaatagatgc acactttatt atctttttgg 334440
gacttgcatt actggcagcg atagggttaa tctatacgtt attttttgcg ttaaaatttg 334500
atgatgcata taaaaatact gagaataaac agccgtgtgt aaaaaccggt gtctatgcct 334560
tatgtcgtca tccgggggtg cacatgatga ttttaatgta tttatgttta tatctagctt 334620
ttcaaaatga aactatgtta tttatgttga ttggatttaa tctattaaat attgggtatg 334680
tgattttaca agacataatt attttcccca agcaatttgt tgattacgat gaatataaaa 334740
aaatagtacc atttcttgtt ccaacaatta aaagtattag aagctgtatt agaacatttg 334800
gggaggtgtc aaaatgaaat ttgaggataa attaaaagca cggagtcgag aagatgtttg 334860
gaatgaatac tgtggctttt tagatttatc gatggatgaa tttgttcaga ttcaaaatcg 334920
tctgatggaa gaacaaattg ccttatggtc acgaagccca ttagggaaaa aaatattaaa 334980
aggaagtaca ccaaaaaata ttaaggagtt tcgtggacta gttccattaa cttcttatga 335040
tgattatgct agcgacttat tacaaaagaa aagcgaactt ttaccagatg aaccggtttt 335100
atggatccag acaacttggg agggtggtaa acatcccatc aaggtggctc cttatactga 335160
aagtatgctg gatacattta aacgaaatgt ctgtgcctgt ttgttattgg gaacttcaac 335220
aaagcgaggg gattttaaag cccgttcgac agatacgatt ttatatggtc tagcaccatt 335280
accttatgca acaggcttgt taccattagc atttgaagag gaaatcggta ttgaattttt 335340
accgcctgtt aaggatgctg tgaaaatgag tttttcaact cgaaataaag taggatttaa 335400
attaggattg tcaaagggaa ttgactattt ttttggttta ggaagtgtaa cttattatgt 335460
tagtttaagt ttaggaaaaa tgagttctgg tggtggcggt gctatttctt tattaaaaaa 335520
atctccatta cgttttgcta agattgtatt agcaaaatgc aaatgcataa aagaaggacg 335580
tgagttaaaa cctaaagata tttttaaatt aaagggattt atggtagcag gaacagataa 335640
tgcttgttat aaggatgatt tagaagaatt gtggggtatt cgtccaatgg aaatatttgc 335700
tggaacggaa ccaacttgta taggcactga gacgtggagc cgaaatggat tatacttttt 335760
ccctgatgct tgtttttatg agtttatccc aagtgacgaa atggagaaaa atttagctga 335820
ttctagttat cagcctcgaa cagtattgat aaatgaggtt gaagaaggaa tgagttatga 335880
attagtaata tctgttttaa aaggcggagc ctttatgcgt tatcgagtag gtgatatgta 335940
tcagtgtatt gatcttaaaa ataaagatga gaatattaaa ttaccgcgat ttaaatatct 336000
cgatcgggtt ccaaatgtca ttgatattgg cgggtttaca aggattactg aaaattcgat 336060
tgatcaagtt gtcaaattat cgggacttaa aatcactaat tatattgcta aaaaagaatt 336120
taatcataat aatcgtccat atctgcatct atatgttgaa atggatccac atgctcaaat 336180
cacccaagct atttcaattg aaatactaag ggaacaatta agcatttatt ttaaatatgt 336240
agatcaagat tatcaggatt taaagaaaat tctaggtatc gatccgttaa aaataacaat 336300
tataaaagct ggaacatttg cctattatga aaaaaatcat tctcataaaa ttaaaaaaat 336360
taatcctcca actttagaaa ttaatgaact gttaacgatt caagatcagg attatcgggt 336420
tgaaatggga ggacgactat atgaataatt atacatatgt ctcgattatt gcgctgtact 336480
gttatatatt tttatttatt tcattatcgg cttcaaagaa aactaagttg attaaagctt 336540
ttatgacatt gttaatggcg atgatgtttt ggactggtgg ttctttcttt atgcgttcaa 336600
tgtttggacc atcagtcaaa ttttggtatg atatttcttt attgggttta tgtctagtac 336660
catatgcgtt tattagtttt gtccatgaat ttttatttaa ttcacctcat aaaaaagata 336720
ctatttggtt ctttcttttt gtcggacttt tcattattaa tgctacaaca gaactcttgc 336780
tgccagcacc tgaatataca ataagggcta gcgggattcc agcattttat tatacttcta 336840
atgtttatac gtatattttt tattgtttct ttctagcaag tattatttat tgtgtttcgt 336900
tgatcataaa aggctttaaa gaaaatcgta atcaggtgat ccggctaatg ccaatgtttg 336960
ctgggattgc atgtttaata tttggaaata cttgtgttat gttggggtgg tttgctggtt 337020
ttccaattga tattgttgct ggggttatta atgcaatatg tatgttctat actttgtata 337080
aacgacgttt atttaggctt aatcttttag tttcacgacg tagcagttat gtaatagctg 337140
gaatgttgtc aattatttta tttgctaatt tagttggtac atttcaaaat attttatttg 337200
aacattttgg tttgattact aaaaattatt atgtattagt aattgcagta gcttttacga 337260
ttgtaactgc gataatttat acaatgttaa aaaaatttat tgatgcaatt tttataaaag 337320
aagaaattca gcaatcagat agtttaaaag agttttctaa ctatgtttca aaaactttgc 337380
aagtaaatga aattgtcggg gcaatgggtg aaataatttt gaaatgtgtc gaaaccaaac 337440
aagtgtatat ttgtctttta gatgacaatg gtgattattc aattgagtac agcagttcac 337500
cgttaagaaa aaataactat attattaatc atgaaaatcc tgtggtgatt aaattaatga 337560
ataacgatga tatgatattt tatagtgaat ttagacattc aataaattat cgttcaatgt 337620
gggacagtga gaaacaatta tttgaaaatc taaatattga aggaattatc ccagttaaac 337680
aagagcaatt aattgggatg atcctgctgg ctcccaaacc acggcgctcg gggtatagtt 337740
atggagaaat tagtttcttg tcttcagttg cttcaattag tgccattgct ttaattaatt 337800
caaaaatgta tgagacagtt tataatgaag cacgtagtga tgaattaact ggactgttga 337860
atcgtaaata tttttatgag gctttgaata atgaatatga aaaattggga gaacgccaat 337920
tatcattgat tttagtaagt gtagatgatg ttcggcttta taatcaattg tatggtaata 337980
aagaaggaga tattgtctta attaatgtag cacgaattat ggatgattat gtaaatacac 338040
aaggttatac agcacgttta gggggaaagg aatttgggat tattttacca aattatggac 338100
ctttagaagc aaaagatctg gccgaaaaca ttcgcgagca aataatgaat atgaataaac 338160
gagatagtga ctatacttta aaagtagtta ctgcaagctt tggtattagt tctattccgg 338220
tatctgccaa tacaattaaa caattattag attatgcaga tcaagcgcta tatcagtcaa 338280
agcgacatgg taaaaatcgt gtatcagttt ataatgcagg agtggttgaa agtacaagtg 338340
gtgtgacgat tgttgatgca catcgagaaa aacagaatat ttacttagag tatgcgccga 338400
caatttatgc attgacagct gcaattgatg caaaagacca ttatactttt acccattctg 338460
aaaatgttgc ttattatgct acaaaattag caatcggatg tggatatgat agtgaattag 338520
tcgagattat taatgaagct gcacttcttc atgatattgg taaaattggg atttcagaaa 338580
atattttaaa gaaaacttct aaattaagtg atgaagaata ccaaattatg caatcgcatg 338640
tggaagcttc agttaatatt attcgacatt taccttcatt ggactacgtt attccaattg 338700
tcttaacaca tcacgaacgt tatgatgggc gtggatatcc aagaagaatt tctggtgaag 338760
atatcccggc cggaggaaga attatggcaa tagcggattc ttttgatgca atgacttcaa 338820
gaaggagtta taaagaacca tattcattag agtatgctct taatgaatta aagcgtaatc 338880
ggggattgca atttgatccc gatttagttg ataagtttat tgaactgata aattctggta 338940
taattgaagt aagaggtaat caaaataatg agtaaggagg aaaaataatg tcattagacc 339000
aaattattaa gcagcgccga agtattagaa aatataaaaa gaagcctgtt tctaacgagc 339060
agatacaatt gcttattcaa gcagcagtcg aagcaccatc ttggaaaaat agtcaaacag 339120
ctcgatatca tgttattaca tcacaacctt tattgaatga gtttaaagag agatgtttac 339180
cggagtttaa tcaagaaaat tgtaaagatg caccggtttt aatagtaaca tctttcattc 339240
caaatcgctc aggatttgaa cgtgatggaa cgcctagtaa cgaactggca aatggctggg 339300
gctgttatga tcttggactt cacaatcaaa atattctttt aaaagcgaca gaattaggat 339360
taggatcatt ggtcatgggg attcgcgata ttgataaaat caagggattg ttagatattt 339420
ctaaagaaga aataattgtt tcagttattg ctataggtat tagtgatatt gagccagaac 339480
ggcctaaacg taaaacggtt gaggatatta caagatttta ttaactatta cttttgtaat 339540
agtttttttg tgcatttctt ttgcataaaa ttttattttg ggctatacta tatccgtacc 339600
ccctaggagg ggggaggagg tcttatgaaa cgtaaatata gtgtaaaagg gatgacttgt 339660
tcagcttgtg aaaatcatgt tcataatagt gtttgtaaat taccgggagt tgaacatgtt 339720
gaggtgaatt tattaacaaa ttcaatgaat gttgaatttg atgaaacaaa agttgatgat 339780
agcatgatta ttaaagccgt aaaagatggt ggatatcagg cgagtagtta tgatgatgca 339840
ttagttgata atgacgactt aagtaatttg aaaaggaaat taatttattg tttcatcgca 339900
cttggattac tgatgtatgt atcaatgtca tcaatgctca gttatccaat ccctaatatt 339960
attagggata atgtttattt taatatcata ttacaaataa tctttttgat tccaattttg 340020
attttgaaaa aagattactt tgttaatggt tttaagaatt tgatccattt tgatccaact 340080
atggattcgt tgattgcact tggtgcggga gctgctattg tctatagtat ttattcagtt 340140
gttttagctt taagcggatc tttaatggag atgcatttag tccataatgt ttattttgaa 340200
tctgctggta tgattgttac attgattagt tttgggaaat atcttgaggc taaatcaaag 340260
aagaaaacaa ctgatgcgat tgggaagtta ttagaattgg ctcctgatgt cgcttgtcgt 340320
tttaatgatg gcaaagaaga aattgttaaa atttccgaat taaaaattga tgacctggtt 340380
ctagtaaggg caaatgaaac agtgccagtc gatggtaaga tagtacaagg atttagttct 340440
attgatgaat caatgattac tggtgaaagt cttccgattg aaaaagaagt aagtagttta 340500
gtgattgggg gaacaaataa tctccaaggt acttttatat atactgtaac aagaacggtt 340560
gaggatagta cattagccaa aattattgaa ttggttgaag aagcatctag ttccaaagca 340620
ccaatgacta gaactattga taaggttgtt aaatattttg ttcctacagt aatcgtaata 340680
gccctaatca cttttgtagg atggttgata atgggagaag atttgaattt tgctattact 340740
agcgcaattg cggtattagt tatttcttgt ccatgtgctc ttggtttggc aactccagta 340800
gcaatcatgg tgtcaacagg agttggagca actaatggga tcctaatcaa aagtgcagaa 340860
gtattagaaa atgaaaataa tattgacgta gttgtttttg ataaaacagg gactctaact 340920
aaaggaatgg ctcaagttag tgatatttat agtcacaaat tagaattagc acaagtaatt 340980
gcgatcattg catcgctaga aaagggttct agtcatgttt tagcgaatgc ttttattcaa 341040
aaagctgctg agatgaattt agaattaaaa gagattactg attttgaatc attaagtggt 341100
ttgggaatta gaggaacaat tgataatgtt gaatatgcag ttggtaattt aaggatgatg 341160
aaagagagtg gaattgattt aagtcgatat caagaaaaaa ttgatttata tttaattcaa 341220
ggtaaaacat tagtattttt agctcatgat caagagctga tagggttggt gagtattttt 341280
gatgatatca aagatacaag tcgtcaagca attcagcgtt taaaagaaat gaaaattaaa 341340
acagttatgc taactggtga tctaaaaggt actgcaaatg ctattaataa acaattaggt 341400
ttagatgagg taattgctga agtcttgcca caagataaag aaaatgtaat ccaacaattg 341460
caagcacagg gcaatagtgt tttaatggtc ggtgatggaa tcaatgatgc tcctgcgcta 341520
gttcgtagtg atgtgggtgt tgctatcggt aaaggaaatg atattgcgat agatgcagcc 341580
gatgttatct tgatgaaaga tgatattcgt gatatagtgg catcgattga attatcaaaa 341640
agaacaatta ttaatattaa agaaaattta ttttgggcat ttatttataa tgtgataggg 341700
attccaattg cagccggtat tttctattat agttttggat taagattaga tgccatggtt 341760
ggttctttat gcatgtcatt atcatcagtt tgtgttgtta ctaatgcgtt acgattaaaa 341820
cgctttaaac catactatca aaaggagaat aagaagatga aaaaggaaat tgtaattgaa 341880
ggaatgatgt gtcaacattg taaaaaacat gttgaagaag ctttaaatgg cttagcagac 341940
acaactgctg cagttgattt agaaaataat cttgctcgtg ttgaaacagt tcaagatgat 342000
agtattttga aaaatgctat tgaaaaagct ggttataaag cggtaggaat taaaaatgtc 342060
taatgaaaaa gtcttattac gtttaaagac agcgcgagga caaattgatg cagttattaa 342120
gatgattgaa gatgagcgtt actgtattga tatttcgaat cagttattag ctattcaatc 342180
actaattaaa aatgctaata atgaggtatt atctaatcat ctcaaccatt gtgttaaaaa 342240
tgcgattaat gagcatgatg cagatcagaa aatagacgaa gtaatcaaat tattaactaa 342300
attataaaaa atcagttatt gaactgattt agtagttaaa tgatgtaatt ttttgataag 342360
tattgttttc aagaagatct actgttgttt gaacgatgat taatcgctta ttcttaacaa 342420
aagcaatgca attataaatt gaatcatttg aaagcagata accattggtt atttgctttt 342480
tatttttaaa gttaacactg tttaaataat cgttcaaagc atttttagct tttttttctg 342540
aattatagta ataataatta acaatcaaag catcattatc attttcttca ttataactta 342600
ttgcctcttt gatcattaaa ctgctgcttt tattaaaagt attatattca tcattgttac 342660
tagatagacc aagtgctgat aatgtaatga tcctatcatt aagcgggagt gtctcacgcc 342720
cgataaaatc gattgaaaat ccagcaataa ttaaaacaat tgaaacaatt aataaccaat 342780
ttgatataat aaatggatat ttgctaattt tattatttgc ttttttatta cttaaagtta 342840
gtttgatctt ttcagtagtg agatgatgat tgaagaaacg gattagtaat gctgggcaaa 342900
ataataaggg aatataatgt aaaattattg acccgttcgt gataaattcc attgggtttt 342960
gattagcaaa aacacctgga atcagtaaaa aagaaagcag catagcgaca aaaataaaaa 343020
taatattgga gatggtctta ttgcgtttaa aataagttag cagcagcgct tgatctgtac 343080
ccttaatatt ggctgcttga gcggctttaa aaacatatat ctttcgtgat ttaccaataa 343140
attcataacc gtggtttaca taatttaata accactgatc acgctgttca cgattgtttt 343200
tagaagattt tttttgaggt acaaaaatat ctgctctata atagagacgt tgctcatctt 343260
ttttaaaaac tgtaaacata tcaacgcttt tgcaattata gcctgacttt gataaattat 343320
ttagcatatc ttcaaattgt ttatactcac tagtatcata attagttaat cttaatttca 343380
taatcgactc cttataaata tattattaga ttatcatttt ttatccaaac aataaagaaa 343440
aaccgtgtaa aacacggttt actttgaaaa tgctgattct ggttcttcgt taagataggc 343500
tgattcatct aataaatacg attcagaaat attttgacaa tgatcgccca ttcgttcgag 343560
attagcaaga atatcgacgt aagttgaatt aactagtgct gaattttcaa ttttacgacc 343620
aactcgtttg atatgacgct gtttagcttt tttgttgaag taatctaaat ctgcttcttt 343680
gtcgtcaaca taaacaatat catccaaatc atgagtatca aaggctttaa ctgcgtgatt 343740
taacatatca atgaccatat ccatcatcgc ttctagatct tcacgagctt ctggtgaaaa 343800
atcttctttt tcatcataga ttgcttcata atatttaaca atgttaatac ataaatcacc 343860
aattctttca aaatctttaa tagttttcat atttgctaaa tagtcattag aatcatggtc 343920
atttagagtt tcatgcgaaa tcaaaactaa gtactcagta attttactgt ctagtgtatt 343980
aatagcattt tccatttcat aaacaccatc tttagctaat gggtttttag tttcaaaata 344040
agctctaatt ccttcaactg cttcaattgt aatatgaccc atctcgatta tcttgttttt 344100
agcaatagct aaagcatgac tcgggaataa ctgaacaaca ttttgatcta attcgcttaa 344160
atccatattt atttcttttt tactgctcgg taagattttt ttgataagtt ttacgattgc 344220
tggtattaaa ggaaaaaaga atgccgtagt tacaacgtta aagattccat gagctactga 344280
taattgtagc tcaggtaaaa tatttaatgc tccagcaagc cattctatca agagcgtgaa 344340
tggcgataag acgatcataa ataatagtga tccaaccaca ttgaataata catggaagaa 344400
agcagcacgt ttagctggta ctgttccacc aaatgaagct aatacggcag taatcgttgt 344460
accgatgtta cttccaaaaa ggaatggtaa agcgatagat aaaccgattg ctccagcacc 344520
gtacatctgt tgagcaattg caattaccgc tgctgaagat tgaactgctg ttgttaataa 344580
tgttccaccc aataatccta accatggatt ttgtgataga taattcgcta cttgtgtaaa 344640
ttctgggact tttgaaatat ttgctaaatt atctcccatt aactctaaac catagaataa 344700
acatccaaat ccaaagatga tttgtcccat atattttgtt tttttgtttt ttgaaaacat 344760
taaaaaagct gccccaagga taataaagta tactgcatat tgagatactt ttaaccctac 344820
aaatacggac gtaataactg ttccgatgtt ggcacccata attattccaa ttgattgttc 344880
gagggtcatc aaaccagaac gaattaaacc aattgctaat gctgttgttc ctgaacttga 344940
ctgaatcaaa caagttacaa atgcacctat tactatacct ttgaatggac tagaagtata 345000
cttatcgatg atatctttca ttttatcacc tgagtatcct tttaaaccat cgcccatgta 345060
ctcaattcca aataaaaaca atcctaaacc tgcaagtatc atcggccaat caatgtccgc 345120
taacgtcata aaatcacact cctatacaca aacataatat agaaatgtta agtaattgta 345180
aattatttgt aaaataaatt aacacaatct taacatttgg ataaaatact taaaattatt 345240
ggataaatat gttattatat ggtgaaataa agagtacaga aggaggttga ataatgagtg 345300
agagatctaa aaaattttta tcgtattacc gtccatattt aaaattattt ttagcagata 345360
tgttttgtgc aatgattgct gcaggaatta cattggtttt tccaatgatt attcgctaca 345420
ttacaggaac agttttaata gctgataatt ttgaaatggg catcatatat aaattaggga 345480
tttttatggt agttttagtt attgttgagt atttatgtaa ctattttgtg gcatatcaag 345540
gtcatgtgat gggggtttat atggagcgtg atctgcgtaa tgaattattt caacattatc 345600
aaaaattatc atttagtttt tatgatgaac aaaaaacggg gcaattaatg tcacgtttaa 345660
caaacgattt gttttcatta actgaacttt atcatcatgg tcctgaagac attgttattt 345720
catttattaa attttttggt gcatttatta ttttagcaac aattaatctt aaattaacat 345780
taattgtttt tgcttttatt ccagtgatgg gtgcatttat ttattattac aatcgtaaaa 345840
tgaaaagagc atttaagcga aataaacaaa gagtagggga tattaatgca cgaattgaag 345900
ataatttatc gggaattcgt gtggtaaaaa gttttgggaa tgaaagtcat gaaattatta 345960
agtttcatga tgaaaatagt cgttatgtaa gcagtaagaa aaatagttat ttttatatgg 346020
gaaaatttca ttcaggatta ggtgctttta ctagtatggt gactgtagca gcggttttct 346080
ttggggctat ttttatttct aatgatggat taaatacagc tgatttaatt gcattcttgc 346140
tttatattaa taatcttatt gatccagtta aaaagtttat taattttact gagcaatttc 346200
aagatgggat tactgggttt gaaagattca tggaaatatt ggaaattgaa cctgatatta 346260
aggataaaaa agatgctcat aatttattag atgttaaagg agccattgag tatcggcatg 346320
tcgggtttag atacaatcaa aaaagtgatt atgtgttaaa agacattgat ttaaaagttg 346380
ctcctggtga gtatattgct ttagttggtt cttcaggggc aggaaaaaca accatttgct 346440
cattactgcc acgtttttat gaagttagtg agggtgatat ttttattgac ggacaaaata 346500
ttaaagatat taaattaaat tcattacgtc aaaatatcgg gattgtccaa caggatgttt 346560
atttattcgc tggaacaatt ttagataata ttcgttatgg tcgctttgac gcaacagatg 346620
aagaagtcat tgaggctgct aaaaaagcaa atgctcatga ttttataatg gaattaccag 346680
atggctatga tactgattgt ggtcagcgtg gagtgaaact atctggtggg caaaaacagc 346740
gattaagtat agctcgggtt tttttaaaga atcctccaat tttaattttt gatgaggcga 346800
caagtgcatt ggataatgaa agtgaacata ttgttcagca atcattagaa tcactggcca 346860
aaaatcgaac aacgttagtt attgcccatc gtttatcaac gataaaaaat gctaaacgca 346920
tttgtgtatt atctacaaaa ggaattgaag aagaaggaac acatgatgaa ttattggcaa 346980
aaaatggcca atatgcaacc ttttataaaa tgcagtttaa taaatagaag tagaagaact 347040
gaaatgaact cagttatttg ggtctccaaa tgaagaatgg tttatttcag aacttctatt 347100
tttttataac aatttaaaga acagtataaa tagttaaaac aagattgtga taatcttttt 347160
tatatcatta ttgttgtgtt aaaaagctga gaagagtaaa ctgtatctat acgattaaag 347220
gagaaatagg atggaattat ataaaataat tgcccttaat aattggaaaa gatcaatgta 347280
ttgtcagttt tttttgagat agtagtgaac aatgtttttg tctgaactta gaagtagata 347340
ctgcgaattt aaaaaagaat ttgagagcaa aattattcat tcacaatggt tttgacctat 347400
gcagtaagta aatatgcaag tgagatagag gcatgcaggt actgattttt tgacggtcaa 347460
atcgttctat atgatcaaat cgacacagcc cttacatatt tagagctaga gatgggatta 347520
tttgaagtag tcatagttgc aatacagcca aagatagaag actatatcca gttggctaca 347580
aaaatggcaa aagaacaaac tgaatattta ctgattcact aggaaataat gtattttaat 347640
tttcattaca gtctaggata ccatattaac atatattaca cactaacttt ggtaagaagg 347700
ataatgagac tctcttattc gactagagaa aatatttcta atatgatggt gaaatacttt 347760
taccattttt aattcaaaca caccatctac ttgttgatga tctacatatg ggtaaatgat 347820
aaaatatagt tatcactttt tttaaactaa attaagatgg gaaaatatga gaggaatagt 347880
atgatacaga tattaaaaga taaacagtcg atgtatacaa ttaatacatc gttgcatgag 347940
ctgcctgtag taatcagctt accgcatagt ggaacatata taacttctga aatggctgaa 348000
aatttaatgg acgatgttat ttttcctaat actgattggt atttaccaaa actgtatggc 348060
tttttaaaag aattagggtt cacaattatt attaataata tgaaccggca tttgattgat 348120
gtgaatcgtg atattaacga taaaaaaggt agttcttata agacaaatct aatttataca 348180
aaaaccactc aaggagcttt aatgtataat cacgaattat cagtacaaga aattgaaaga 348240
cggattgctg attattattt accttatcat gaggcgatta gacaagcatt gctagagaag 348300
caaaaatatt ttaaaaaagt ttatttaatt gatttgcata gctttggatt gaattatggc 348360
gcggatatta ttcttggtaa tgataatggt cgtgcttgta cttctaaaac tacaaatttc 348420
tttaaaaaaa tgatgaagaa gcaaaatttt aaagtgactg aaaataatcc ttttgcagga 348480
ggctatatta ctaaatatta tggagccagt gttgaaaatt gtgaggcaat tcaaattgaa 348540
ttgtggtatc aaacatatat agataaacgt tcttttggca atgaggagct gccggtaatc 348600
aataacgagt tatttggtga gacaagccgg aggatggaaa acgtgtttat tgaattaaaa 348660
aaatggctaa aggatgaata attttaatga aagaacaagc tatagatagt gcattgattt 348720
taagaaaaag ctttgagcat ggtgaagctt tttctgaaat agaaatatct gaattattaa 348780
aagaatctaa attagttgaa aaattgacaa gagattatga agacagttcc ttctttaata 348840
tttttagact tatttgttta tcagaaatac catttattga acaattgcca tatactcaaa 348900
aaatcattga ttttatatct aataatttag ctgctgatga aggtttttca tataatggac 348960
aaggtgattg cattgttcct tgttacaatg caatgctttt agaagcatat actcgattgc 349020
aaatggcaaa gagtaatgaa gcacagaatg ctctagattg gataaaaaga tatcaagtat 349080
ttgagagaaa tcaaagaaca tcttggcgat atggagaaat ttgcaaacat ggcggatgta 349140
tgaaagctac accatgttat attgggattg gtaaaactgt acgagcattg attacttatg 349200
ctaaatatat taaaaatgct gattctcatg tcgaacaact gattgaacag ggaattgtat 349260
atatgttaaa gcacaatatg tatcagcgct tatcaaatca gcaatgcatt agtaaatata 349320
ttgataaaat catgtttcct caagcatata tgttatcatt gacagattta gtatatattg 349380
taaatgaacg aaatttatgg tgggatcaac gtacgattcc gttgaagaac ctccttgaag 349440
agaagcaagt aggttcaggc caatggaaaa tagaatatat ttatagtcat aagggataca 349500
aagcttttga aactaaaaga aattcctcga aatggataaa ttatttatat aacttaaata 349560
agtaggaaga aaaatgtgtc aagaatgtta tgtggatgaa agacgctgta cgtcattatt 349620
aaattcgcta gtttgtttag aaaaacatac tcagtatatt tgtggaacgt gtggaagaaa 349680
tatctgtata gaatgtgatt taaacgaggg ttataaaggt ggacttttcc atttaaaagc 349740
cttgaaattg ctaagatgta tttatgtaca gctgattata gttaaaaaaa catgtgtgat 349800
atatcgaatt gaaaataata atggagaact tcttataaga tttttagtag tactggttat 349860
ttgaaagagt atctaaagaa aaatagtgat aaagtatgaa agaaatggca ctaatattta 349920
aaatggataa atatattaag tattcgggaa ctgaagtgcg taaattaact tttgcggaaa 349980
tagaaaaata tcttgatgaa aggcaataga atgttttgaa agtgtaaatt acaaacagtt 350040
tatgtgaaga gcatgcttaa atggagaaat tagtgagaaa aataatttta tatgttgcaa 350100
tacgccttga tggttatatt gttcgtggag atgtggcgtt acatgggcaa ggtgttaatt 350160
cagataatca aaatagcaat caagaatttt taaagatata gatacagtaa ttatgggatg 350220
gaatacttat catcaaattg taacagaatt gtcacctaag atgtgggtct atgacaattt 350280
gattactcat gtttttacac acaaatatta tgaaaatgga gctaaaatta aatttactaa 350340
tgatgatgct tacgattttt taaatctttt aaaatcataa gtaggaaaaa atatctggat 350400
ttatggaggc acaaatctga tttcacaatt aattgaaaaa gattttatag atcgttatca 350460
tatgacgatt attcctacaa ttttaagaaa ggaaattcgt ctttttgaaa ctactcatga 350520
ttatgaaata aaactaaagt tgattaaatc actaagttat aatagaataa gtgattgttt 350580
tatgaacgaa gataacattt tattataaaa gaatttatat ttttgttaaa aatggtagtg 350640
atgttattga taatatcgct accattttta aattaaaact aattaagtta tttaattgaa 350700
ttatttaaga gataaattat ttattattga tctttccttg ataacatgaa ttaccgacaa 350760
gatcatcttc aatttttaat agacgattat atttacaaat acgttcacta cgagacatcg 350820
aaccagtctt gatttgtcca atatttaaac cgactgccaa atcactaata aaagtgtctt 350880
cactttcacc agaacggtgt gaaataattg gagcaatctg gttttttaca gccatttcaa 350940
tacaatcaat agtctcactt aaagtaccga tttgatttaa tttaattaag atactattgc 351000
tatagtttcc tgcgattccg gcttttaacc gattggtatt agtaacaaat aaatcatcac 351060
caactaattg aattttagct cctagtctac tagtaagttt tttccaacca gtataatctt 351120
cttgatctaa accgtcttca atagagataa tagggtattt gcttacaagt tgttcgtaat 351180
atttaattaa ttcatcactt gtatattgtt taccattaat tgtgtaaata ccattctggt 351240
atagttcact ggcagctaca tcgagggcaa ttgaaatatc tttgccaggt tcataattac 351300
attctttaat agctttaatg attaattcta gggcatcatc attggattcg agattaggcg 351360
caaatccacc ttcatcaccc acagaagttg ctagattact tcttttcaaa atatctttta 351420
aagtatggaa aacatttgtt gccatttcca ttgcttgata gaaagaattg gcactgattg 351480
gcataatcat gaattcttga aaatctagtg agttagtagc atggcttccg ccatttacaa 351540
tattgatcat cggggttggt aagacatgag cattgcaacc gcctaaataa cggtataatg 351600
gaatttcaag atagtttgca gcgcaatttg caaccgccaa agatactgcc agcatggcat 351660
tagcacctaa tttttcttta ttttctgtat tgtcaaagcg aatcattgct aaatcaattt 351720
ctcgttgttc taatacactt ttttctttaa ttagtttggc aatagtctca ttcacattgt 351780
ttattgcttt aaatacactt tttccacgat accgtgcatc atcgttatcg cgtaattcta 351840
aggcttcata ttttcctgtt gaggcaccac ttggaacaat cgcacttcca gaaaatccac 351900
tttccgtagt tacttcaact tgaattgttg gaaaacctct tgaatctaat acttgtcttg 351960
catatacatt tgaaatatat ggcataattt tatcactcct tcatttttta ttatgaacgg 352020
ctttaatttg ctttaatcaa atatattatc ttgtttttaa taattattat acggtaataa 352080
aggagttttt tattaatgat tcatgtaatt gttaattcaa aggtacttta caagattgga 352140
tacaagtgct aatatgcaat taattttaga gatgttaatc aagtgctaga taaaggggag 352200
aacacgaatg aaaataaatg aagaaagaaa tttaccaatt ggattcattg attctggttt 352260
agggggatta agtgttttaa aagaggcgat aaagataatg cctcatgaag attttatata 352320
ctatggtgat tctttaaatg ctccttatgg aaccaaatca gtagatgaga ttagagattt 352380
aacctttgct atcgttgata aattattaaa attagggatc aaaggattag cagtagcgtg 352440
taatactgca acaagtgcag ctgttcgaca gcttagaata atgtatcctg atttaacaat 352500
agttggaatt gaaccagcaa ttaaaccagc agttgaatca aaccatggtg gtgaaatctt 352560
agtaatggca acacctatga caataaaaca agaaaagttt aaccggctgc tagatatcta 352620
taaagaccgt gccaaaataa taccagtatc atgtaagggg ttaatggaat ttgtagaaca 352680
tggaaatttg aatgggagct ttttagaagc atattttaat gaaacacttg tcccttattt 352740
aaatgatact actgaaacaa ttgttttagg atgtacgcat tacccctttt taagaccgta 352800
tttaaaagaa tttttaggag agcgaagaat acagattatt gatggcagtc atggaacttc 352860
atgtgaatta aagcggcagt tagcaggaaa aaaattattg cagaaagaaa atcatgaagg 352920
gaaagtagta ataaaaaatt cgatggatga accagagatg attgatttga gctggaaatt 352980
attgaatttg ccaatcgatt aagttacata caaattttaa aaatggccga attggccttt 353040
tttagtgtga tacaaaaaat gttaaattat ggttaaattt tcgtataaga gtgcaataga 353100
gtatacttat aaataaaggt tagttttaaa atatttagcg agtaaaagaa catgattaaa 353160
ttttgaatgt tctttttata ctgttggaaa atataatata actgcttata aagtgtaaaa 353220
agataattct ttgggaggat tcctttatgc gtagaaaatt atttttaatt gttctaacta 353280
cgtcactatt gttatctagt attatttcga tttatgtaat tcataatctt caaggaaatg 353340
ccagagttat caattatact ggtgttgttc gtggtgcaac gcaacgattg atcaaacaag 353400
aattaagtaa taagccaaat gacaaattag tgaaaaaaaa tagatgatat tattgatgaa 353460
ctacaaactg gacatggtga acttggtttg attcgtttag cttctgatga tttccaagaa 353520
aatatgactc aaatgaaatt tgattgggag gggttaaaaa aagaaattta tttggttcga 353580
gaaggcagag ataatgggaa tttatatttt tatagtgaag ccttttttga gttggcagat 353640
aatacggtac attctacgga attgtattct gaaaagagcg tgtattcagc agaaggaaca 353700
ttaataattt tgaatctagc gttagcaata ctagtgtttt ttatttataa gtataatact 353760
aaacaagaaa aaatacgaaa aaaattagag aaagaggaag aaaataataa acaacgtaaa 353820
gtataacttg caagactggc tgaaaacatg cgcgctccct taaatgatat ttctgaactt 353880
ttatatattg ttgacttaga aacttatgat ttattattta ttaatgaaac cggaatgaaa 353940
atatttgagg ttgattcaat ctatggaaaa aatgttataa agtcttacaa ggaagagatg 354000
cgccttgtaa ttttgtacta actgctattt gaaagaagag gaaaattata cttgagaatt 354060
tactaatccg ctaactaaac ggcattacct gttaaaagat cgtttaattg agtgggatgg 354120
taaggttgca agaatggaaa ttgcttttga tactacagaa tctgagatag aaaaacagca 354180
gttaaaattt acacttgagg ctgaaaaaac gattacagaa tgtattggta tattatatcg 354240
tgaaaatggc gttagtactg caattattga agtgttgaga aagcttggga attttttatc 354300
agcagaaaga acatacataa tctatattaa agatgaacta atgtataatg actatgaatg 354360
gtgtgcggaa aatattatat cacaaaaaaa caccctacaa ggaattcctc ttgcaatgat 354420
tgatcggtgg attccttatt ttaaaaatga taaatgtgta atcattgaaa atttagaaga 354480
aataaaagaa atttcattgg aagaatatga aatactagac agtcagtcaa taactagctt 354540
agtgtagctc cgttggaaca aaatggcgaa ctggcaggtt atttaggagt tgataatcca 354600
cctccagata aaattattaa tattgcttca ttgcttcaaa cattatgtta tttcgtttca 354660
ttagcattac aacatgcaga gagtcaaaaa aaattatcat atttgagtta tcatgataat 354720
tcaacgacct tttataatcg taatcgttat attaaagata ctcaaaaact ttttaatatg 354780
gatacttcat tgggaattat ttatttagat gtaaatggtt taaaagatgt aaatgatcaa 354840
tttggacacg aagttggtga cgcattattg gttgaatgtg ctagacgtat gaaaatggta 354900
tttaaaaaag ctgattttta tcgtattggt ggggatgaat ttattattat ttgtcaaagc 354960
ataaaaaaag agtcatttga aaaacgagtt aaagaattaa gtgaaagttt ttctaaaaaa 355020
ccagtttgtc aagtagcgat aggaacacaa tggactaatg cagtaggtaa tattaatgag 355080
atgattgctg aggcagatgc aaggatgtat gaaaataaaa aagaatttta tcataagcat 355140
atgatttcca gacggtatcg tcaccatagc gatgagatgc tgcatctcac taatattgat 355200
tatctagaat ctgagattga aaacggtcat tttgttgtct atctacaacc taaaatttta 355260
tgtgaagatc gctcatgtgt tggggcagaa gcattgatac gttactgtga taatgctggg 355320
acattaattc cgctttcaat aaatttttct atagaatcac ttcgtggtaa atcttttgtt 355380
gaacgtattt tagaaacttg taaaaaatat caaataccta ctaaatatat agaaatagaa 355440
ataacagaac gagtacatga cgaaaagaat tttgaaatta aaacggtaat atcaaaactt 355500
cgtagtgctg gatttattgt agctattgat gattttggaa cggagtatgc caatttagca 355560
ttattatcgg atgctgagtt tgatattcta aaattggata agagcttaat tagtaatgtt 355620
gcattaaatc caagaactaa gataatcatg gaatatattt caaaaatttg tcatcgatta 355680
gggctggata tgatagcgga aggaattgaa tctgaagagc agttttttac gctgtgttca 355740
tatggggttg aaacagttca aggttattta ttcagcaagc cgttggcaat aaatgttttt 355800
gaagaaaagt atctaagtta attttaagaa gctaattaaa gtttatttaa ggtgttgtat 355860
gtgaagtgta taaataataa catttatttg actttatttt ttagttgtca ttgacattgt 355920
ctatataatt atctagaata taagtatata gacgtggtat tacctttaaa tcaattatag 355980
cctaagtatt agtatgagca atttttttgc ttgctttact taggttttat tcttttaaaa 356040
gtaatgaatg tttactgatt caatcaagta tgacaaaata gatggacaag gagtgtgaaa 356100
aattaaggga aaacaaatat tgttagtact tggtaataat ccgcaagtat caaatacttg 356160
ttgcaattta tttaggcctt tgatttattt tagactagag aagggtaaag gagcaaaaaa 356220
atgaaaaggt tagggaaaag gagaatcatt tcgctaatta tggctttatc aatggctgtt 356280
acaactgtat ttagtgcaaa catttctaat gttagagcgc taaccaatgc agaaaaagca 356340
agggaacttg tcagtaaaat gacattagaa gagaaaatcg ggcaaaagtt aatgttatct 356400
ttccgtagtg gatggacaat gagagatgga actaaaattt catcggttca aactattaac 356460
gatgaaattc atgagattat tggtgaatat gatataggga gtgttatctt atttgctgct 356520
aactttaatt ccgatgcaaa agtaaatgta gaattgacag atggtttaca aaaagcagca 356580
atggacaaag atttaggtaa aaacagtatt cctctattaa ttgctactga tcaagaggga 356640
ggaatcgtat atcgtttaac tggtgggacg gccttaccag gaaatatggc tttaggtgct 356700
agcggtaata ctgaaaatgc tgttaaagca ggtaatatta ttggtagtga attaaatgcg 356760
gttggtgtaa atgttaattt tgcgccagat gctgacgtaa ataataaccc taataacccc 356820
gttattggat tacgttcatt cagtagtaat ccgcaattag cagctaaatt tgtttctgct 356880
tatattgaag gagttcaaag caataatgtg gcaactgccg ctaaacattt tccagggcat 356940
ggaaatgtag ctacagattc gcatacaggt ttaccttcgg ttcctgcgac taaagaagaa 357000
ttatataaaa cagagttagt accttttcag gcggcaattg atgctggaac agatatggtt 357060
atgactgctc atatccaatt tccgaatatt gtaacagaag aaatttactc agataaaaaa 357120
gatgagctga tgagtccgcc agctacatta tctagggaaa ttttaactga tttattaaga 357180
gatgaaatga agtttgacgg tgtcattgta actgattcta tgacaatgca aggtgtggct 357240
aattactttg atacaaacga aagaaactta ttagctgtta aagctggagt tgatattcta 357300
gatattccat ttacggatat ttcttctatg aaagatatgg aatctaaatt aattccactg 357360
attaatgcat ttgtcgatgc ttatactaaa gaagatggtt ataatggaat taaattatca 357420
ttagaagaat tggataaatc tgtggaaaga attttagttt gtaaatacaa cagagatgtc 357480
atggatttag caaatgatac aactacatta gatgataaaa aagcaatcgc ttcgaaagtg 357540
gttggttctg ttgaaaatcg tgaaacagag agattaattt ctgcaaatgc agttactgtt 357600
gttaaaaatg aaaataatgt attaccactt aaattgacta aagattcaaa agtagtattt 357660
gcatcaactt attcaaggaa taataatcgt tttattttgg cttggcaaag agctaaacag 357720
gcgggaatta ttccagaggg ggcagattat aagattttgc agcactataa ttggacagga 357780
ttaaacgata aggtaaacag tgctataaat tctgacggaa ctaattttgt tgggacaaat 357840
aaagatgtgc tagattgggg tactgttctt gtccatgcct cagaaatcag tagtgctagt 357900
ggaatagatg gatatttggt agcttgccca caattattta ctaagtattg taaagaaaat 357960
ggaaagcaga cggttgttat ttcattaaat catccttatg atgttcaagc cttcccagat 358020
gctgatggta ttttagcagt gtatggaact actagtcttg ggctggatat tacggaatca 358080
ttcggtggtg gtacagttgg agcaacagca gcatttagtc ctaacttgac agcaggtact 358140
gaagtagctt taggtacatt tggagcttct gggaaactac cggtagatat cccaaaatat 358200
gttccaaaat ctggagtata ttcaactgac gaaaatgtct atgaattagg atatggtata 358260
gaatatgatg caattgctaa agatccagat aaaaaaggac tagcagatgc gattgcacaa 358320
gctaaagcta tagataaaag tgtatatact actgagtctt gggaggcagc tgcagaagct 358380
ttaaatactt taaaagtcgt attgcaaacg gctgaaaatg ttaatttgac tcataaattg 358440
gcacagtctg ttgttgatga aaatgaaaca gatttacgtg ataaatataa tacggtttta 358500
tcattattag tatataaatc tgacaaaaaa gctttatcag atttgattgc cgaagcgaag 358560
aaattagata aagatcatta tactattgaa acttggcaaa attttgaaaa agcattagaa 358620
aatgctgaat ctatatatga tggaaatgta ccacaagatg aagttgattt agctaaagaa 358680
gcattagaaa aagcaaaaaa tgagttactt gagaaaaata aaaaagaatt atcagttgct 358740
cttgaaatgg ctaaacaagt aacaccagaa cagttagata aggttgtacc agctgtggtg 358800
actgaattta aggctgcatt ggaaaatgct caaataattt ttgataaaaa ggatgcaaat 358860
gaacttgaaa taaataaagc ttttgaacgc ttatctaatg taatgcaaat gttggaattc 358920
tataagggcg ataaaacaca attaagtgca ttagtagaaa aaattgaaaa attaaacaaa 358980
aatgattatt taagcgcaac atggaaaaat ttagaatccg tcttaacaac ggcaaaagat 359040
gttttgaaca atcctgatgc tttagaaata gaagtaagtg aaacgcatga tcaattagta 359100
agaacctttt tacaattaag attaaagcca aataaagatt tgttaagtga gttgatcaat 359160
aaagctgaaa atacagatca aacaaaatat acagcagtat cattattatc gcttaagagc 359220
gcattagtag aagcaaaagc agttcttgat aataacgaag caacccaaga tgaagtaact 359280
gctgtagaaa tattattgaa aacagcatta gacaatttgg tagtgaaaga aattactcta 359340
gatgatccaa atgctcaaac accaccagat gctaaaccag gtaatggtgc tataactgcg 359400
acaaaaacag gtgatgattc tatgatgtta acatttgcct tagcgggatt attggcttta 359460
gctggcagtg tgattgtatt gaagaaaaaa gaagaataat ttatacttaa gctaaaaagt 359520
cactgtatat agtggctttt ttgttttggt ttgttttgag aaacaggatg atttatttaa 359580
taagaaatat gttataatat tcctaatatt attttatagt acattggttt aaacaatatt 359640
tatttaaaat actaaataaa cttcacattt attagttaga aaggggaatt tttaatgaag 359700
cagcaaaaat ggaatattca tacgcataca acaagatgtg ggcatgcaac tggactagat 359760
attcaataca ttcaaagtgc aattgaggct ggatttacaa tgttaggatt tagcgaacat 359820
ctgccttatc ctgaaatacg gatttctggg gcacgaatgt tttatgagca aaaagatgaa 359880
tatattgcaa cgataagaaa attaaaacaa gattatcaag ataagattga tattaaagtt 359940
ggctatgagg ttgagtattt aaaagatcat tttaatgatt tgatgaattt gaaaaaagaa 360000
tgtgattata tgattttggg acaacatttt aaatatttaa tttatgacta tgacagttat 360060
tgttctgatg aggatgtata tgtttatgca cagtaaatag aggaggcatt atctaaaaat 360120
tttattacat atgtagctca tcctgactat tttatgatgg ggagaaggag tttttcaaat 360180
gcttgtgttg atgcggcgca tcgaatagca aaagctagca tccgttatga tacaccgtta 360240
gaaattaatc taaatggttt tggatatgga aaaaaacaat attatataaa caatgaatta 360300
aaggcatgtt atccatatcc gtttcgtgaa ttttgggaga taattgctat gtatggttgt 360360
aaagtaactt ttggatatga tgctcattca ccacttacgt tattagagcg tgagcgggaa 360420
tgttgggctc tagatatttt aagtgatcta ccacttaatt ttattgacca tatcgaatta 360480
aaatgagctt tatagataaa atattatgct taaaaattat tattaactat attttttgat 360540
tcaaataaga ttagtaattt aagaaaaagg agattagaaa tgttgtactc aaagaagata 360600
aatatggcag atattagagc aagaatatga gtatgtttct aatgttctag aagacaaaaa 360660
tgattttgaa aataaaattt tgccaggtta tattaattct tccaacggga ttggacttct 360720
tgagggatgg gttccggaaa cagaagtgtt tttatggaag atgatcaaat tattgactga 360780
tttaggattg gacattactt gactgaaaag ttggctcatg gtaccggaca tatcggatat 360840
gtaataaaaa agaatataga ggaaacgggc atactgtgaa ggattaaagg taactcttca 360900
aatagctaaa aatattatta aagaggataa aatatatctg tcagtccata aaaataatct 360960
agcttcatta aaaatccaat aaaaaaatgg tgcatatatt catcatgaag acgataagaa 361020
attttataca cgaataaaaa atcagtttaa agctactcta taattaatta aatactagta 361080
aagccggcta aaaacaatgt acaataaata atgggttatt tttaaatact aataaataac 361140
ttgaattaaa aaaataacta tattttaatt tggaaaggaa ggtatgcatg cctgttaatt 361200
gctagtttag caaagctagg caattgagat tattagttgc gtactaaagg gagtggaatt 361260
atatatgaga aaatatttct tttttgacat tgacggaaca ttaactaata gtaatcctgg 361320
gggaattatt ttaccctcaa cttttgaaac attagataag ttaagaaaaa atggtcattt 361380
tgttgcaatt gcgacaggaa gagcgcactg gatggcaatg gattttagtc atgaatcaaa 361440
aattgataat ctagtttgtg atgggggaaa tggtttagtc ataaatggag aattactagg 361500
aattgaacca ttagataaaa atatttgttt agaaataatt gatgagtgca tagaaaagaa 361560
atttcctttc ggtgtatctt taggggatgt tcctgaacta tatacatgta atgagtggct 361620
aagtaatttt aaaatgcata caaaaattat tgtagaccca cagattgatt ttcatcgggt 361680
tgataatatt tataagattt ttattatggc tacacacaag caggaagctg agttgactgc 361740
aatccataaa cttggttata tgcgatatca tggtgatcaa ttaattgttg agccgttgga 361800
aaaatatcgt ggaattttga aaatgattga aatacaagga ggaaaacctg aagatatagt 361860
tgtttttggt gatggacata atgatatttc aatgatgcga caagcaccta tttcaattgc 361920
aatgggaaat gcaattgatg aggtaaaaga agtagctaca tatataacta aatctaatca 361980
agaagatggg attgaatatg cttgtaaaca ttttggatgg atagattagc taaatgtggt 362040
atactactag taggtgatga aaaatggaac taataaaatg gattttaatg atagcaggta 362100
ttttggcttt tttaattatt ggctgtatga tattgctacg tagtgatgaa aaaaagcgga 362160
gtcgaactaa acagtaccaa gaaaatattg atatgctcaa cgaaactaat gaaatgttag 362220
atactacatt aatggaatta gaatcttata atgaaccgct aaagaagata tgtgaacata 362280
ttgataactt taatcataaa tttcttggtc aaaaataacc gaaaacagtt gacataagat 362340
tattttttca tataatacag gtatatataa aaactcgttg ataaagagag taatttaatt 362400
aagtttctta gcgaactggc gttggtgaaa ggtcagtaaa caagattaaa tgaaccgcac 362460
tttgaagagg actgtttgaa ctaatagtag ggcagtcagt atgtctactt tacagacaag 362520
aggggatata agacttttta tatcaacaag agtggtaccg cggaaatttc gtctcttagc 362580
ttttaattag ctaagagact tttattttac gcaaggatag gaaaggaaag gtaagaaaaa 362640
tgaagaaatt attaaaagta ttattagtat gtacgatggc atttacactt gctgcctgcg 362700
gcggaaacag cggtagtgat ggtacgaaag aaattttgat tgggatttct ccagattatc 362760
caccatatga gtctttagag ggcaaagata tggttggatt tgatattgat atgactaaag 362820
agttgtttaa aattatgaat gataacggtg gtaattatga atataaattt aaacaaatgt 362880
catttgatac aatttctaca agtctgattt ctgatcaaat tgatttagga atttctggat 362940
ttacaatgca taaagactgg gatgtattat ggtcagacaa atacaatgat tctagacaag 363000
ttgctttagt tgctaatgat agtacaatta ctactaaagc tgatttagag ggtaaaaata 363060
ttggagctca attggctgct actggtgaaa gtgtagctaa tgatattaaa gatgctaaag 363120
ttaaagcagt aaaagatgtt aaagttttaa ttgaaacttt aaattctggt gggattgatg 363180
caatcatctt agatgaagca gttgctaaaa actatgtaga acaaggcgga tataagatgt 363240
tagatgaaac tttattagaa gaagaaaatt taatcatcgc taataaagga agtgaagatt 363300
taattaaaga catcaacaaa gcacttgctg aattcattaa atcagataaa tatcaagaat 363360
taaaaactaa gtggggagca taaacgtgga tgcattagtt gctttttgca cagcagacaa 363420
tttgattttt ttactacaag gggctggtaa atctttatta ctagccgctt gtgctttgtt 363480
ttttggcctt attcttgggg ttttaggtgc tgctgcaaaa atttcaaaac ataaaatact 363540
aagacttatt ggaaatgttt acgttgaatt gatacgtgga acgcccatgt tgttacaaat 363600
actttttctc tatattgctt ttccgttatt aatgcgttcg attactgggg aaagatttat 363660
tcctgatcca tatgtttgtg gtgctattgc gatgagtatt aatagtggtg catattcgac 363720
agaattgatc cgtagtggaa ttatgggagt tgataaaggt caatgggaag cttgtgaagt 363780
attaggacta aattatacac aaacaatgaa attaatcatt ttgcctcagg cgtttaaaag 363840
aatcattcct ccaatcgtca gtgagttcat tactttaatt aaagattcat cactaatttc 363900
ggttctagga gcaactgaat tattatattc agcacaaatt ttgggggcga atacatttaa 363960
tttgattccg ccattattgg cctctgctgt attatattta attatgacct taacaacatc 364020
ttattttgcg agaaagatag aaaggcggtt atctgtaagt gattaaagtt gagcatatta 364080
ctaaaaaatt taacgattta aaagcagtga atgatgtctc tttagaaata agaaaaggag 364140
aaatcgtttg tttgattgga cctagtggaa gtgggaaaag tacagtgtta cgttgtatta 364200
atggattaga aattcctgaa gaaggaactg ttttcataaa tgagcagcca ttgaatgcta 364260
aaaaccctca agcatttaaa gaacttcgta gcaaaatggg atttgttttt cagcatttta 364320
atctttttcc acataaaaca gttttagaaa atctaacatt agctccaatt caggttttgg 364380
gaatggaaca agaggcagcg aatcaaaaag cattagagct gttaaaacga gttggattga 364440
gtgataaaaa agatgtttat ccaaataaat tatcgggtgg gcaaaaacag cgtgttgcta 364500
ttgctagagc actatgttta ggaccggaag tgatgttgtt tgatgagccg actagtgcgt 364560
tagatcctga aatggttatc gaagtattgg aagtaatgca ggaattagca aaagaaggaa 364620
tgacaatggt ggtagtaact catgaaatgg ggtttgcaag aacagttgga gatcgtgtga 364680
ttttcttaga aaatggaaaa attattgaag aagcaaagtc ggaggatttc tttacacatc 364740
caaaatcaga gcgtgcaaaa gatttcttaa gtaaggtgat gcattaatga aaattgattt 364800
atttgatgtt gaagcttgga tgactgaata tgaaaccaac tatcgatata atttggcgga 364860
aacttgtgta gcttcaatga gtattaatga tttattagaa ttggttgaaa ataaaaaagg 364920
agtcattgat aatttattaa atactaaatt ggactatgga cctattgttg gtagtcaaag 364980
attgcgggaa gggattgcaa gattatacca aaatggtgat gccgataaca ttacgattag 365040
tcatggctgt atcaatgcta atgagatggt tttaatttct ttgctcgaag ctggtgatca 365100
tttaattacg attacaccga cataccaaca attttattct tttccagaat cattaggtgt 365160
tgaaactacg cttattccgt tgttggagga aaatgattgg ttacctcggt taagtgattt 365220
cgaaaatgca attaaggata atacaaaaat gatttgtctc gttaatccta ataatccaac 365280
aagtacaaaa ttttctagag agtttctaga aaatttgact gatttagcaa aagaatacca 365340
cttatatatt ctttgtgatg aggtgtatca aggattaggt gatggtgaag tcgcaatcag 365400
tgatttatat gataaaggga tatctacagc ctctttatct aaagttacat catttgctgg 365460
tttacggtta ggctgggtaa aagctaatta tgaagtaatt aaactgataa atgatcgtcg 365520
tgattatcat attatttcaa caggttatct taacgattat cttggaactt tagttattga 365580
aaattatcac aagatacttg aacgaagtag aaaaattatt aatactaatc gacagattct 365640
cattgattgg ttagctcaag agccattggt tgattgcgtt gttcctgaag ctggaacaat 365700
agccttttta aaatatcatc tttcgataaa gtctagggaa ctttgtgcta aattacaaca 365760
ggatacagga gtgttttttg ttccaggggc atgttttgat caagaatatc atttacgttt 365820
tggctttgct aataacagtg acgaaataaa aacaggatta caattatttt caaaatggct 365880
taaagaaaat gcttaatttt attctttaag cttttttatt atcgataaat agatatttat 365940
aacaagcgac catattaata aatagtgcaa cgacaatgcc gattaacata ctgacagcta 366000
tactgaaaac ccctagtgac tgactaagaa aatatattaa aactatttct aaagtacatt 366060
gaatgatgct gattgcaaac attaaacgat ttttattcaa agcttgaagc agtgcactaa 366120
gaggggtttc taaataaaag atagtgaatg gaatgcacat atattttaaa taagtagctc 366180
cgcttgttgt atcataaagg atttttaaac aaacttctgg atataaataa aaaatcaatg 366240
taaacggtag actaattaaa aaactaccaa tcatagcaat tagaatatga tatctagcag 366300
cgctgatttt atgataaact acatcattag tgatgatcgg gagaatcagg cgataaatta 366360
cgccattaaa aaaagtgggt gtaactaata atgatatgac ataaccgctt ataattgcat 366420
attgttgatg gatcatactt tcttttaaac cgaatttggt taaaacatag acgaggatga 366480
ttggctctag aaagctaact aaacattgat ataaacgtga accggttaat ggcatagcga 366540
tatttaacat atctttaatt tgcaaattat tgacaatact ctgcttatta aaggttgtaa 366600
tatgatggtc cttgagacgg gttgtcaaat agaggatgga tgctaattca ccaacagaca 366660
ttgccagtgt tgcaaaacta actagatagg tatctgttaa gaaagaaaat tgtctaatca 366720
ttaaataact aaaacttaat cgagcaactt cttcgacaaa gccagcttta gcaactaaaa 366780
agacattttg tttcgctaaa aaataatttt taattattcc actaatccct acgagcggaa 366840
taaacaatgc cagtgacaac aaaggataga aagcaccctc attttttaaa aggttatgac 366900
taataaattt cgatgaaaaa agtaaggcac tcatgacaat tatacaagta aaaagacaaa 366960
tcgttaaacc ggagatgaca atttttttat tattatattt agggtttgct acaagtcgaa 367020
agactgctga aggaattcct aattgaccta aggtaatgca taatgaaacc gttggcatta 367080
ctaagatata tagtgccatc gcttcttgtc ctaattgtcg cgctaaaatc atgcgattaa 367140
gaatactaaa caattttgtg attgctgaac tagcggaaag aatgataaaa gaatttatta 367200
gttttctttt cataaagcac ttcctttctg gtgaaatttg tcatataata tgtaagtgac 367260
ttttgaatgg agggctgaaa atggaatcga ttaatgattt taaatttaat aaacgtgacc 367320
taaatttttt aataaaacta aaagcccgtg attttaaaca gcagaatatt cataatattt 367380
ctgaacaaca aattaaagac tacttatttg agcgcaaatg gaaacaaaga gatgccgttc 367440
ccatgtgtga aataattgat gatatcatga atttagattt ttctgaaatt tttgattatc 367500
tgagtttaca agtagttaaa gaagcatctc gtttgagtat aaatgatttt tcggacttta 367560
tttcaaaata gttgctaagg caactatttt tctttgaaag gagattatat ggattggcgg 367620
attattaatg atttagacta caaccactat atgcaagaat acaagattaa tgcactttta 367680
gctaaggttt ttgcgtataa acaatattca tctcaagaaa ttgaaacaat gttatcaagt 367740
cgtttagtat atcatgattt ttctttattt tctgaagcag aaatgacatt agaaagaatt 367800
catgaggcaa ttggtaataa agaaaaaatc tgtatttacg gtgattatga ttgtgatggg 367860
attttagcaa catcaatttt agttgaagct tttagacaat taggagtgga agtgggatac 367920
catattccga gtcgtttaga agatggatat ggattaaatg caaatcgtgt tgaacaaatg 367980
gcaaataaag ggtatacatt aattattacg gttgataatg gaattaaggc atatgaggca 368040
atcgaaaaag ctaatgaatt gggagtggac gttattgtta ctgaccacca taattatgat 368100
gatgaattac cagatgcttt ttctattatt catacaaaaa tctcacccga ttatccttat 368160
aaagaaatct cgggtggttt tgtagcttat aaattagcaa gtgcattatt aaaaaagcat 368220
gataaatact tattttcatt ggcagctatt acaacaattt ctgatatgat gccattactt 368280
gatgaaaatc gagcattggt aaaaagagca ttggaattta tgaaagaaaa taaatatcct 368340
caattagaat tgttattggg gagtaatcag acctatagtg ttactagtat tgggtttatc 368400
atcgccccga agattaattc atttggtcgc ttaagtgaaa ttattaatcc taatcatctc 368460
gttaaatatt ttagaagtga tgcttcaatt ggaatattaa aagcagttag tgaaaaagca 368520
attgaagtaa atgctaaaag acaagaatta acaaataaac aatatcaaag cgttttaaca 368580
atgattgacc cgaatgagca atttttatat gcttatcaaa atgaaataca cgaaggaatc 368640
attggtttag tggcaggaaa atatactcga caatataacc gacctagctt tgtgatgaca 368700
tttgatagtg aaaaaaatct ttataaaggc agtgctcgtg gaattgaagg gataccgttg 368760
aataaaattt ttgaaaatgt tcaagatttg ttagaaagtt atggtggtca tgctttagca 368820
ggtggattta gtgtaggtag tgataaagtt gaggagctaa aagaaaaatt agaattgtat 368880
ttaaataaac aattaaaaga ttatactcct cctttagtgg atgtaattga agttacagga 368940
aatgagatta gtaaagttag tgtaaaacaa ttagagttat tagagccact aggcaatggc 369000
aatgaagaaa tgcgtttttt cataaaagat ttaccagtaa gtaaagttac gtcgttatcg 369060
aatggtaaac atattcgttt tgatttgtca ttaccgcaag tcaaagcaca agcgttattt 369120
tttaatcatg gagatttttt tgaacaatta aaagatacta aaatgatcaa tgcagttggt 369180
aagtttaata ttaatgtttt taataatatt gaatctgtca acttaattat tgaagatatt 369240
aaatagttta aattaaagta taaaaatgtt ataattaaat atcataggat attatgtgga 369300
ggaaatagaa tggatttaac taagtatgtt gcaagtattg aaaactttcc tgaagatggt 369360
attattttca gagatgtaac accgttgatg gctgataagg aagcttttaa agaaacgatt 369420
gaccgatttg ttgagtggac taaaaatctg gatactaatg ttgatattgt tgctggacca 369480
gaagctcgag gttttttatt tggatgtccc gttgcatata atttaaatgc agggtttgtt 369540
ccggttagaa aaccgggtaa attacctcgt gaaacagtaa gtgaaactta tgctttagaa 369600
tatggaacta atgaagtgca catgcatgct gacagtatta aaccagggca aaatgttatt 369660
attgtagacg acttattagc aactggtgga acagttgaag caactgtaaa attagttgaa 369720
aaattaggtg gaaaggtagt aggaattgct tttctaatcg aacttgaagg attaaaagga 369780
cgtgataaac ttcaagggta taatatctat tcaatattga aatactaaaa agagattaaa 369840
tctctttttt aataataaga gggggtgaca ttatggctga atataaaggt gctggcgata 369900
cagttacaat taatgatgtt cttgaagtgt gtggtaaata tattacaaat caagaaagta 369960
ttgatttaat taatcaggca tacgatttta ttatggagaa gcatgagggg caaaaacgca 370020
aaagcggtga accgtatacg attcacctga tttgggtagc atatattttg gcaacgttac 370080
aaacgggacc cgctactatt gcggcaggac ttttgcatga tgtcatggaa gattgtggag 370140
tatctcggga agaaatggta gaacgttttg gtgaggaaat cactacgtta gttgaagggg 370200
ttaccaagat tggtaaaatg ccatttaaag atgaatctga tgtttatgct gaaaatcatc 370260
gtaaaattta tattgctatg gcaaaggata ttcgcgttat tttgattaaa tttgcagatc 370320
gacttcataa tatgcgaaca ttacaattta tgccacctca taaacaaaaa agaatttctc 370380
gagaaacgtt agaagtttat acaccaattg ctcatcgttt aggaatcaat gatatcaaaa 370440
cagagttaga ggatttaagc ctatcttatc ttgatcctgt tgcatatagc gagatatcaa 370500
aattattagc gactaaacaa gaagaacgga aagaatcagt tgcaaaaatg atggcatcgg 370560
ttaaacaaat attggatgat aatagctatc agtatcgtat cttgggacgg gctaaatcaa 370620
tctatagtat ttataaaaaa atgtttgtaa aaaagaaacg ttttgatgaa ctttatgatt 370680
tatatgcatt aaggatcatc actcaagata agatggattg ttatggaatt ttaggcttga 370740
ttcatgatca atatcgcccg attccaggac ggtttaaaga ttatattgct atgccaaaac 370800
caaatatgta tcaatctttg catacttcag taattggtga ggatggaaat acctttgaga 370860
ttcagattag aactgaagaa atggatgagc tagctgaatt aggagttgct gctcattggc 370920
gctataagga aaataaaggc tattcatcga agaaagaaca acaagaaatt ggtgaaaaat 370980
tgcagtggct tagagaattt atttctctaa gtgacgatat taaagacggt gatgctaaag 371040
agtattatga ttcattaaag cgtgatatct ttgaggccaa tgtttatgtt ttaacaccgc 371100
aaggaaagat cgtagagtta ccgaatggtt ctacaccaat tgattttgct taccgaattc 371160
atacggaagt tggacataaa gcagttggag ctatcgttaa taatgttatg gtgcctattg 371220
atactaaatt aaatactggt gatgtagtcg aaattaaaac taataagcag tcattaggac 371280
ctagtgaaga ttggctaaaa tttgttcgaa ctgcaggtgc gcgtaataaa attagacaat 371340
ttattgctaa tcgtgaggca gaaactaaaa aagagacaat tgaagatggg cgtaaaatgc 371400
ttcgtgatga attgaaaaaa cgccaattag atgaaaagaa atatatggat ccagatacgt 371460
ataaaacata cttaggttct tttggtgccc gctcatttga tgatatctta tattttattg 371520
gtaaaaaaag tttaccggca atgaatctgc tggatcgagt tgtacctaaa aagtcggggt 371580
tctttgacag tatttcgaaa atgcttcagc gaaataatca ggtaaatgaa aaacagcagt 371640
cttcgcgtaa taattcgggt gttgttgtta agggattaga tggactaaga attcaacttt 371700
caaagtgctg taatccaatt cctggagatg atattatggg ctttgtctca caaggtcagg 371760
gaattaaagt acatcgtcga gactgcccga atattcaaca gcctgaaatc aaagcaagat 371820
tgatagatgt ttattgggat tttgcatcca tttcaacgat gaaatttcaa gcagatttag 371880
aaatagttgg tttggatcga cctaatttat tgaatgatgt ggtaacatca ttagggcaga 371940
tgaaaattaa tattttgaat atccatgctg atgttgtaga tatgaaagca atcattaaat 372000
taaagatttc agttgaagat gctagtcgtt tacaacaagc aatcgataat attgatcgga 372060
ttcagggaat ctatgaaatt aaacgggtta ttcattagtt attgcaattt tatgaaatat 372120
tatatataat caatttaatc caatgaacaa gattaagtag ttaaatcctt ttatagagag 372180
aatacgtctg gtgaaagtat ttaaaggatc attacgggac acttgggagg agttactttg 372240
aaatctagta ggagtaaacg tctgtcgcgt taagacataa gagcgtgtta tttaacacga 372300
attaaggtgg taccgcgtta actaacgtcc ttattttaag ggcgttttta tattatcaag 372360
gaggaaatga aagatgatgt ataaagcacc acgaggaaca gtggatattt tgccagaaaa 372420
gagtgctaaa tggcaaacat tagaacaact aattagaaca atatgtgcta attataatgt 372480
taaagaagtg agaactccta tttttgaaca caccgagtta ttcactcgtg cagttggcga 372540
tacaactgat gtagtaagta aagaaatgta tactttcgct gataaaaagg ggcgttcaat 372600
tacattacga cctgaaggaa cagctggagt tgcgagagct tatgtagaaa ataaaatgtt 372660
ttctaatcct gataaaatta gtaaattata ttatattgga ccaatgttta gatatgaacg 372720
tcctcaaaat gggcggcaac gtcagtttca ccaattcggg gtagaaatga ttggttatga 372780
atcaccatat ttagatgttg aatgtatgac aatggcagta acattagtcg aggctttagg 372840
gttacaaggt gtcaaattac atataaatac tcttggtgat ggtgatagtc gtgatgctta 372900
tcgtgaagct ttgaaagcac actttgcacc atatttagat gatttatgtc aagattgtaa 372960
aaatcgttat gaagcaaatc cgttaagaat tttagattgt aaagtagatc ataatcatcc 373020
agcgatggca aatgcgccaa aaacagttga ttatttaagt gaagcggcta aggcacattt 373080
taccaaagta tgtgagttat tagatgatct agaaattgaa tatgttgttg atacaaattt 373140
agtgcgtggt ttagattatt actgtcatac agtttttgaa gtaatatctg atgatccacg 373200
cttaggtgca ggagccactg ttggtggcgg tggtcgttat aatggcttag tacaggaatt 373260
agggggacca gaagcacctg gagttggatt tgcttttgga atggaacgat tattgattgc 373320
tatggatgaa gaattagaag aacctgaggg gttggatgtg tatgttatgc caatgggaga 373380
tgaagcaaga gatttagcgg tacagatcac ggcaatgcta cgagcaaatg gctttagtgt 373440
tgatatggac tatcaaggtc gttctttaaa agcacagttt aaaacggttg atcgtttgaa 373500
tagtcatttt gcaatgatca ttggtgatca agaaattgct gacgaagtag tcaatattaa 373560
atgtacacat tcaaagacac aagatattgt accaattgaa aatattgttg cgtatattga 373620
aaatcatatg gagggacatg tacatgaata gaactcataa caatggtgaa ttaagaatta 373680
gtgatgttaa taaaattgtt gaattaaaag gctgggttgc taaaaaaaga aatttaggtt 373740
ctttggtttt cattgattta agagaccgtt atggaatcac gcaaatcgta ttaaatgaag 373800
aaatggaagc tctaggtaag gatattaaaa atgaatatgt cctgcatgta gttggtaaag 373860
taattgaaag aagttctaaa aatcctaata tgccaactgg ggatattgaa attgaagctg 373920
ctcaaattga tattatcaat acggctaaag taacacctat ttacacaact gatgatactg 373980
atgcaagtga ggatgcaaga atgcaatatc gttatcttga tttaagaaga ccggtaatgc 374040
agaataaaat aattatgcgt cataaaatta ctagcagtat tcgaaatttc ttagataatc 374100
atgaatttat tgatattgaa acgccctatt taaatcgttc tactcctgag ggagcaagag 374160
atttcttagt cccttcacgg gttcataatg gttcatttta tgctttacca cagtcaccac 374220
aattatttaa gcaattattg atggtttcag gatttgaacg ttattatcaa atcgcacgct 374280
gttttagaga tgaggattta cgattagatc ggcaaccgga atttactcaa gttgatgttg 374340
aaatgagttt catgactact gatgaaatta ttagtattgg tgaacagctg ttagcacaag 374400
taatgaaaga tgttaaagga attgaactgc aactgccatt gccacgaatg acttggcatg 374460
aagctatgga aaaatatgga attgataagc cagatattcg ttttggatta gagttagtta 374520
atttaaatga agtggttaaa gatgttgagt ttatggtttt taagagcgcg ttagaagctg 374580
atgggcatgt aaaaggaatt aatgtcaaag gtgaagctga caatttttct cgtaaagcaa 374640
ttgataaatt gacggatgta gttaaaacat ataaagcaaa aggattagca tggttaaaag 374700
ttaaagctgg aaaggctgag ggaccaattg ctaaattctt taacgaagaa caaatgacaa 374760
aattattaaa agcaatggat gcaagtgata atgacttatt attatttgtt agcgatgcta 374820
aatataatgt tgtttgtgat gctttggcag ctttacgtaa tcatttagga aaagaattaa 374880
aattatttaa ccctgatgaa tttgcatttt tatgggtcgt agattttcca atgtttgaat 374940
atgatgatga aactgaacgt tattatgcgg ttcatcatcc atttactcga cctaaagata 375000
gtgatattga taaaattgaa aacgatcctg caaattgttt agctgatgct tatgacattg 375060
tattaaacgg ttttgaattg ggtggaggtt cacaacgtat ctacgaacaa gaattacaag 375120
aaagagcctt tagagcatta ggttttaccc aagagagaat tgatagtcaa tttggctggt 375180
ttgttgaggc ctttcaatac ggtactccac cacatggggg atttgcctta ggtctggatc 375240
gtctagcaat gttacttact ggtagtgaaa atattcgtga ggttattgct tttccaaaaa 375300
atgcaagtgc agtatgtcca atgtcaaaag caccaagtga ggtagataat gctcaattag 375360
aagaattagg aatcgcggtg attgaagatg aacaagaata gaattgatgc agttgtaaat 375420
aatatgaagg aagctggtct tgattatttg ttgatcagtg aaccttcttc aattgattat 375480
ttgattgatt atgtaaataa ccccggtgaa agaatgtatg tattgatgct tgcagcaaat 375540
ggtgcccata agttgttctt caataaatta ttctttgtag aaaatgatct agggattgaa 375600
attgtttggc atagcgatac tgatgatgcg acaaaaacaa ttgcagatta tgttgaaaat 375660
tctggtacaa ttggagttga taaacattgg agtgcaaact ttttattaag tttaatggaa 375720
aaactaccag atgttaaatt tgttaatggc tcattttgtg tagattttgt aagaatggtt 375780
aaagatgaaa atgaacaggt tttaatgatt gaagcaagtc ggatcaatga tcaagcaatt 375840
catgaagtga ttcatcaagt atctttagga ttatcagaac ttgaagtagc cggtaaattg 375900
agtggtattt atagcaaatt tggtggtgat ggcaacagtt ttgatgctat catcgcttat 375960
ggagctaatg gtgctaatcc tcatcatgaa aatgatgata gccatttaaa accaggtgac 376020
agtatcatta ttgatatggg gtgtaagtat aacggatatt gctcagatat gacaagaact 376080
gtcttctatc aagaagtaag tgaagaagct aaagaagtct atggtttggt tcgtttggct 376140
aacgaaacag ctgaagcaat gattaaacct ggggttagac tttgtgatat tgataaggct 376200
gctcgtgata ttattactga tgctggctat ggcaaagaat ttaatcatag gttgggtcat 376260
ttcattggta aagatgttca tgaatttggt gatgtttctg ttaactttga tttggaagtt 376320
aaagaaggta tgattttttc gattgaaccg ggaatttatt tgccaggtaa atttggggtg 376380
cggattgaag atttagtcat ggttacaaaa gatggctgta aagttttaaa tagttatcca 376440
aaggatttat ttgtaattta atgattaagg gttacagctc ttaatcattt tcttgtcgaa 376500
taaaaaaaca tactttttag ggttcggtca atacatttat cttaaattgt gctaaaatgg 376560
tgaagtgagg tgacataaag aatgtattat tttattggaa ttaaaggttc agggatggcg 376620
ccattagctg aaatccttca tgaactagga aatgaagtgt gtggaagcga tattgataaa 376680
tacatcttca ttgaagagga attaagaaag agaaatatcc caatctattc atttgatgct 376740
aacaacatta aagatggtta tacagttatt attggaaatg cttttggtga tgatcacaca 376800
gaagttaaag ctgctttagc taatccgaat gttaaatgtt atcgatattt tgaatttttg 376860
ggagagttta tggaaaactt catctcaatt agtatagctg gaactcatgg caaaacaacg 376920
acaacaggga tggcttatca tttgtttgaa gaatttgata aaactacagt tttaattggt 376980
gatggaactg gtcatgcagt aaaagatagt aaatatttta ttgcagaatc atgtgagttc 377040
caagatcatt ttttacatta ttatcctaaa tatgcgatta tcaataatat tgaattagat 377100
catgtcgatt attttggaaa tttagagcgt tatattgagt cttttgaaaa atttgctaat 377160
caagtaaaag atacagtaat tgtttggggg gatgatccaa acattaaaaa aataaatttt 377220
aaaaaaagag ttatgagatt tggtttaaat gactataatg acgttagggc ggtaaatgtg 377280
cttgaaaaca gtaatggttt atcgtttgat gtatatattc ataatgaatt atttggtcat 377340
tttaatttac cttattttgg aatgcatatg ttgtataatt cattagcgat cattacgctt 377400
ggttatttag aaaatatgac taatgattat attcaaaata gaatggcaac tttcgaggga 377460
acaaaacgac gatacagtgt aactgaagta gggaataatg tttacgtaga tgactatgcc 377520
catcatccca ctgcaattaa gtatgtaatt gaagcaaccc gtgttagata tccgagtaaa 377580
aaaattgtag caatttttaa acctgatcgt ttttcacgtg gcgctcgttt tgccgttgat 377640
tttgccaaat ctatggattt agctgattat ccatatttct gtccatttcc cgaaaatgca 377700
gtgaaagaag aaggaattga catagatatt tatgatatcg ctaataatct accaagagca 377760
aaagttattg gtgaagatga agaagctgct aaagaattag ctaagttcga taatgttgtg 377820
ttcttgttta tgtctagcaa agatatttat aaacttgaag aaaaagttat cgcgataaaa 377880
aaatctatat aagtatctag aattatggta taattatttg tagaaagttg aggtaatgct 377940
atgactgcaa ttgatgtttg ttactgtgtt ttaatacttt ctggagcatt tgccttagtt 378000
agcttaggaa ttttattgct tcgtagttca accacagtta aacaagtggg gaacacagtc 378060
gaaatggctc aaagcacaat taataaagcg gataaaatta tggatgatat aacttacaag 378120
ttagatcttt tgaatgcgcc agtagaaaca atcgcgcgtt tctttgatcc aaatcgacct 378180
aagtttaatc ctataagtgc tattattgga ttgttcaaaa agaaatttta gaaaggtgaa 378240
ataatgatga aattaggaaa atttattgcc ggtgtaggta tcggtgcagt aattggaatg 378300
ttatgtgctc ctaaaaaagg tagtgagcta agaggtgaat taaaagaaaa gtctcaagat 378360
ctatatgata aagctcaaaa catgactaaa gatgatgttg aatctttgat caacaatact 378420
atcgaagaaa tcaaattagc aattgatgaa tttgatgttg atgaatttaa agatacagca 378480
ggagaaaaat taggagatat taaaactaaa ttagaacaac tagcaacttc ggtaaaatct 378540
agtgatgaat acgcaagttt taaagaatcg gttgctaaag ttagtgatga ggttacaaca 378600
aaatttaaag aaatcaaaac aaaagttcaa gacaaagatt ttaatgtgtt acaagaatta 378660
gatgatgcaa tggatgatat tgaagatgaa ttagatgtca tcattgagga tctaaaagat 378720
taatgaaaaa agtaactatt tatgatgtcg caagagaagc tggtgtttct cttgcgactg 378780
tttctcgagt aatcaacggt tcaaatgttg ttcgagaaaa aacaaagcaa aaagtcttgg 378840
atgttattga tcgtttagat ttcaaaccaa atgatattgc tagaggattg gctactagca 378900
aaacaacaac aattgcaatc gttttcccac aatcactatt tgctcatgtc aaagatatga 378960
ttggtggaat tggcgatact ggtagacatt tagattataa tatcaatatg tatacgactg 379020
atgatattgg tgatgaaaat acagttgctg atgttactga aagattagta aagtcacgtg 379080
ttgatggagt aatcttattt aataatgata atattgacga aactgttgaa tcgattgtga 379140
agtataattt acctatcgtt gttatcggaa caaaaatgtc tggtgaaaac attggttcta 379200
tttatattga tgttaaaaaa gctgctgagg agattgttga taaatatcta gctaaaggta 379260
aagatgacat agtctatatc ttaccaaaac aaaatttaat taaaagtgat gaaattattg 379320
aaggaatcaa ggatacatat aaaaaatata acaaagagtt tactaccgat caaattgtta 379380
caagctctag ccattatgaa aatacatatc cgaattttgt tgaatatttt aaaaatcaca 379440
aacatgattt agtattctgt ggatatgata aagacggtgt tgcgattatt aatgcagctc 379500
aagaaaatgg aattaaaatt cctgaagaaa tggaagtagt aggaatgctg aatacaagtt 379560
attcaattat gtgtaaaccg accctttcat caatgaatgt gcctgtttat gatatgggtg 379620
ctttagctgt tcgtttatta actaagttcc tacaagatga agaaattact tcaaaagaaa 379680
ttgcagtaca acatatgttt attaaacgca attcgacaaa tgactaagac tttcattatg 379740
aaggtctttt ttttgtcacg atttataatt ttcaattgtt atttagatga agggaggaaa 379800
tttaatggag gaagcaatgt tcgaacacct attccaaaag tataaagata tgatatatcg 379860
agtcgctttt ctttatctaa aaaatgaggc agatgcttta gatattgttc aaaatacatt 379920
tattaagcta ttaaagaaaa atgattttaa cgatgaagag catcttaaaa gatggttatt 379980
aagagtttgt attaatcttt gtaaaaataa tttaaaaagt tattggaaaa gaaatgttag 380040
tgtttttgaa gaaaaatttt atcaattaga aaatagtgat ttaaaattgc aagaactagt 380100
ttttaaactg gctcctaaat ataagggagt gattcatttg tattattatg agggatattc 380160
agtgaaggaa atttcagtca ttttaaaaat tagtgaagcc gctgttaagc aaaggttaaa 380220
gcgagctcgt acaaaattga aaatagaact ggaggcagaa tcatgaagaa taatgattac 380280
aaaaagattg tcaatggaat caagatacca gagcaaaagc ttgatctagt aaaaaatagt 380340
attttacaga aaaaaagcat ctgtaaattt aaatatgcta cagctttaat cgtgatagca 380400
gctatgatca cgggaacaat ttattttaga acttatccaa gaggagataa tgaaacaaaa 380460
acattaatag atgttgatta cttcattaca aatatttatg ctaatgatga aacctatgaa 380520
ttaacagacg ataaagttag tattgacatg agtagtgata tgtttggaac aacctggaga 380580
tgtaatgcta aacgctcatg tttaccattt gatattcgta ttgttggtga aaacattaag 380640
agtatcagct attctgtaat taaggggacg agcttagatt tttatcgggt taaatcatta 380700
gatttatttc atgatgattt atcggagtta aataaaaaaa atgattttag tatccaattt 380760
aaaatgttta acgaattacg tgatcaagat aaagaacttt taaaagaacg ctatcagtta 380820
acagaagaaa atttagaatc atacgttaat gatcatatca ttgatattat taaagattac 380880
cgtgcagctt tagaacaagc aggctatagt caggaaagct taaatatgta tggcggactt 380940
ttttggatag aaattaacca aggcgatagg atgactgttc cttatgatca gcaagatcct 381000
ctaaactatc gaaatattct ttatactgaa ttaaatttag aaaataaaga tatttcagta 381060
atagataacg aacaaataat ctatcaaaca gttaaacagg aattattaag ctatgaaata 381120
agcatggtaa tagagtataa taatggtgtt atcaaagaaa aaataattac ttttgaagaa 381180
ggaacttgtg aagaaagaaa taatgaatgt agggatacta tttatatgaa aataaagtaa 381240
atcattaaaa ttaaatatga ttaaaatatt taaatagtat caggaacgat aagttttgac 381300
aaaactatta gggtatgttg acttatttaa aaatatagca tataattcta ttacgacgtt 381360
gaaggaaaat agtaatcaaa ataggcattt tagagacctt gtggctggtg taaacaagga 381420
tgtactactg atgaatacac tctggagttt ctaggtgaaa agtctagacg ggtagttccg 381480
ttatgaatga tgagtgcatg tattttatac gtgaataaag gtggtaccgc gagatttcgt 381540
ccttttagga agaaatctct ttttatttta taaatggagg ataacggatg aagatttatg 381600
atgaattagt atggcgtgga ttaatcaaag atgttagttc accagattta gaagaaaaat 381660
taaataatgg tgggatgact ttttatattg ggactgatcc tactggtgat agtctccata 381720
ttggacattt ttcatcattt ttaatttcaa agcgattaaa agaagcggga cataatccaa 381780
ttttattagt tggtggagca accggattga ttggtgatcc taaaccagat actgaaagac 381840
caatgattac caaagagaca gttgaacata attttgcttg cttaaagaaa caagcacaag 381900
atttgtttgg ttttgaagtt gttaataatt atgattggtc aaaggatctt aatttcattg 381960
attttttaag agattatgga aaatatttta atattaacta tatgttaaac aaagatattg 382020
taaaacgtcg tttagatgca gggattacat atactgaatt ttcatatatg atcatgcaag 382080
caatggactt tgaatggtta tacaataaca aaaattgtgt tatgcaagta gctggtcaag 382140
atcaatgggg aaatattact gctggaattg aattgattcg caaaaaagat ggtaaagagg 382200
catatggttt tacaatgcca ttattgacta aaagtgatgg aacaaaattt ggaaaaacta 382260
atggtaaggc tatttggcta gatagagaga aaacatcacc atatgaaatg tatcaatttt 382320
ttattaactc agaagatgat aaagtaattg attatttaaa atttttaact ttcttaacac 382380
ctgaagaaat tatggaatta gaagaaaaga ataaaacgca accacattta agagaagctc 382440
atcaagcatt agcgcgtgaa gtaatcacat tcttgcatgg tgctgaagct tatgaggaag 382500
ctgtaaatat ttcaaaaatg ttattttcgg gacaaattca atcactaaca ttagcacagg 382560
tcaaggtttg ctttgaaggt gtaccaagta ttgaagttaa tgaagaattg aatattttag 382620
atgcactaac tacttgtggg gcagcaaaga gtaaacgaga agcgcgcgaa tttgttaatg 382680
gcggatccat tttaataaat ggtgaacgaa ttaaagatgt tgagttcata gttacaaaag 382740
ctaatgcatt tggaaatgag gcgactgtag ttcgtcgcgg caagaaaaat tattttgtaa 382800
ttaagcatat ttaaaaaagt aagttttata acttactttt ttcttggcgt ttttttccat 382860
aacattgtat tttcttcgtt tgttaaactg gtaaggagat tgcttttagc ttgcggatat 382920
tttaaatata gatcatttag taaatgttta aattcttctc gtttagtatg cttatcagct 382980
ggacatgttg aagggacaat aggaacatgt gcttcttcaa cagcactaac tatatctgat 383040
tcgtaagcat aaactaatgg acgaataaag ttcatttcag ttcttgttaa atacattttg 383100
ggggtaaagg ttgcaatctt accaccgtag atcatattca taaatagtgt ctcaacagca 383160
tcatcaccat gatgcgcaaa ggcaactttg ttgcatctgt atttctttgc accatcgatt 383220
acaagtgctt ttttaaattt agaacataat gaacattgta gacgaccatc atcggtctta 383280
tttaacttta agatttcata tacatcacta ggttcatgat aaagttcaat accatttttt 383340
ttacaaaaag catcagcttc actaaaatcc atatttggga agcccatttc aatatgtact 383400
ccaataacat caaattttac agttgcgaat tttttatata atgataagca gtataaaagg 383460
agcatagagt ctttaccacc agaaacgccc acacatactt tatcaccatc ttgaattaaa 383520
ttaaattctt catcggcttt acgaatacag ccaagtactt ttttcattgt catttttatc 383580
accttgctat attctaacaa aaatatcatt actaagcaaa gttatttgca atttaatgta 383640
aagataggta caatgtaaag cggtgatgaa aatggatgga attattttag taaacaaacc 383700
tagtggtatg acaagccatg acgtggttaa taaattaaga cgaatattaa aaacaaaaaa 383760
agtggggcat tgcggaactt tagatcctga tgcaactggt gttttagttg tgtgtgtaaa 383820
taaggctaca aaagttttgc agtttttaac aagcgaaagc aaagaatatg ttgcaacact 383880
tagtctagga acaagtactg atacatatga tgctagtggt aaaattattg aaacaaaaga 383940
gttccatgcc cttgataata atgaaatagt tgcttgtttc aataatttta ttggttctca 384000
agaacaaaag cccccaatct attcagcaat taaagtaaat ggtaaaaaat tatatgagta 384060
tgctcgtgca ggagagcagg tagaagtgcc aacacgatca gttacagtta atcatttaga 384120
aatattacaa atcgaaaata atttaattaa atttaaagtg ggatgttcga aaggaacata 384180
tattcgttct ctatgctatg atcttgcgaa ggctttaggt tatccgggac atatgaaaga 384240
tttaattaga actaaatcag gaaatttttc gttagaaaat tgttttacac ttgaacagat 384300
tgaaaatggt gaatacacaa cagtaagttt agaagaagct ttaaattcat atcaacaatt 384360
agttgtagat gatgaaaaaa taatttttca tggaaaaaaa atcaaatcag atttaaatga 384420
acaggttgtt atcttaaatc ggcaggggaa agttcttgca atgtatggcc ctgatggaaa 384480
tggttattta aaaagtatta gaggtttatg gtgatgaaag taatatattt gaatgaagaa 384540
aatatgattg ctttggaacc aagttgtgtt gctttgggtt tttttgatgg catgcatcta 384600
ggtcatcaaa aattgattga tgaagtatta aaagtgtcaa aaataaagaa tctaaaaaaa 384660
gggctattaa catttgacgt tcatcctaaa tcatatcttt tagatagttc ttttaaatat 384720
ttgatgagtc tcgaagataa aatagaattt ctagaaaaat taaattttga ctatttattt 384780
gtattacgtt tcaatcatca attagctagt aaggaaccac gacagtttat tgacgaattt 384840
attattaaac caaaaatcaa gcatgttgtt tgtggttttg attttcattt tggaaatcat 384900
ggtagtggcg atagtgttta tctaaaaaat aatagaaata atgattatga aatttcaatt 384960
attgataaat tagaatatga acagcataaa atctcatctt catatttacg acaagtttta 385020
agtaatggtc aagttgaatt ggctagtcaa ttgttaggtc ggcaatatca agtgactgga 385080
aaagttgttc atggacgtga aaacggtcgt aaaattggtt ttccgacaat taatgtggca 385140
gcaatagatt atgtacttcc taaaaatgga gtgtatggtg ctaaagtaat catcgatggt 385200
aaagaatata taggaatggc aaatttaggc tataatccaa cctttactgc tttgaagcaa 385260
gcttcattag aagttaatat tttcgatttt gatcagaatg tatatggaaa acaagtaaat 385320
gttatgttta ttaaacatat tcgcagtgag aaaaagttcc cttcaataaa cgatttaatt 385380
gaacaattaa ataaggataa acagcagata attaatgaaa tgatatgatt agtacatatc 385440
atttttttat gttgctttcc tatatttatt agttttattt atgaatatct ggggaataat 385500
aaatttggtg atatgatgtt atatggatgg ttaatctttt ctagtttttt atggggtacc 385560
aacgttcttg taatgaaata tatgttagaa aacactacaa catatttttt agctgctcta 385620
aaagtactgt tgtcggttat tgcaattttt gtaatcatga aatataaaaa aatacctttt 385680
aaatggtata aaggcagtct aggaataaag gtatcattac tttcgattac aattaatttt 385740
atacttacct ttgagggatt gaatttaatt accggaagtt caaatgcaat tgttaattcc 385800
ttagcaccgc tagtgacaat cctattgaca tggctttttt atcatactaa ggtcaatcgt 385860
taccagttga ttgctatgat aatcgcatgc attggatttc ttatttctct agattttaat 385920
attagtcaga tttctcttgg tcatttaatg atgattggtg gaattgtgtt atatagttat 385980
ggtaatttat taatgcagca ccaatgtaaa aaagaagaca gtttgccttt tacatttcaa 386040
tatttatgtt tgagcttctt tcaattagcg ttaattactt tatttattcc tagcagcaat 386100
catcttgaaa atatttcaat aactttatgg gtatttttca taattttttc tggaattgga 386160
tttgctataa ttcaattaac gtattttcga gctgttcacg aaattggaag tgttaaaaca 386220
agttttttat taggactaaa tccagtgttt acatatattg gttcattgtt actacaagaa 386280
aattttaatt ttaataaatt tatggcgatg attttaatgg ttgtagccat ggttattgca 386340
aacaaaaaaa gatagttagt tcataactat ctttgataat atttaataag agcttgagtg 386400
cctaagttct caaatccgtc ggtttgtaat tgttcaaact gttgtaaaac agtatttaaa 386460
acttctaagt caaggttgtt tgtatcatta acagctttgg ctattttcat atctttgata 386520
taatgtttta tgtaaaaccc cggtgcaaaa tcatcagcaa gaattcgtgg ggcattatta 386580
gtcatttgcc atgaaccagc agctccactc gaaatacagt caagcattat ttgagggtcc 386640
aaattgactg ctttagcata tgtaagagct tcacaaactc cagctaaagc tccggctaaa 386700
gcaatttgat tggccatttt tgtatgttga ccgtttccgg ctgaaccaac ataattaatg 386760
ttgcttccta agacttctaa cactggttca atttgtttaa agacattttc atcaccgcca 386820
accataattg acaatgtccc ttttttggca ccaatatcac cgcctgatac cggagcatca 386880
agactggcta aactatgttt tgaagattct tcaaaaattt tttttgctaa caatggacta 386940
gacgtagtga aatcaatgag aatacaatct tttttagcat tagcaattat ccctttggaa 387000
ctaaagtaga tttcctcaat atcttgagga aatcctacca tagtcatgac aatgtcttga 387060
tctttgacac actcagcaac tgaatcgtgc catataattt tatcactaat aagatcttca 387120
actttatttt ttgttcgcgt ataaatagat acaggatatc ctgcttgact caaattttga 387180
accattgctt tacccattac tccgacccca ataaatgcaa tttttttcat ttttcttcct 387240
ccagtaactc tttatataat ttaattaaat ctgcttgaat tttatcatga tttttttccg 387300
gatgccattg tacagcaata atattatctt tttcaatgcc ttcaataatt ccatcagcag 387360
taattgcact gacaacaaag ccaggggcaa tatcatcaat tgcctggtga tgaaatgaat 387420
tggtcataaa ctcatttcct aaatatttat ttagttttgt atgaggaata gttttcacga 387480
gatgatgata tccttctaaa ttttcctgga gatgattatc atattttttt gtctcaggaa 387540
tatcctgaat caaagtaccg ttaaatgcaa cattgatagt ttgaattcca cggcaaatcc 387600
ctaatatagg tttatgagct tttgaaaact tatgaatcaa cttaatttct aattcttcca 387660
attctgcttc ctctttattg gttagaggat ttaatacttg atggtataaa acgggatcaa 387720
tgtcaaatcc gccgcttaat aatagaccat cacagtgagt gactaaaaaa tctagtgtat 387780
catcactgct cggtccaata ataataggat ctagatttgc agtttgaagc attctaaaat 387840
attcacggta aatataataa actctgcgtt gagaatagct tcgcattggc gttaagattt 387900
ttttattcat aaactacctc ctgtatttat atattacgcg aaacaaaaat aatgtaaaga 387960
attataaaaa taatttaaaa ctgcacagat attacttaga catcatatga cacttatgat 388020
atactttatt agtaagattt ataaaaaaga gggatgtaat ataatggact ttttagataa 388080
tatattaaaa aaatttggaa caaaaaatgt aatcatagta ggggtagtat taattgtaac 388140
tattgtgatc ttaataacat actggatgat taaattaaga atatatcgta aagaaattgt 388200
ggttttagaa aatgatatga atgcaattaa aactttgcca attcaatacc gcttagggcg 388260
gattaaagca attggaaaaa acatgccaga tgttttagaa aaatatgatg attttgaact 388320
agaatttaat gatttagtaa atctacaaag taatgaaatt gcgccattga tcaatgatat 388380
tgatgagcga ttgttttatc gaaaattaaa aggggttcgc agagatctaa ataaattaag 388440
acaagatatt gataattatg agaaacgttc taaggcgttg cttaaagaaa ttgaggtgat 388500
cactgaaata gaaaatgtgc aacgtgtaga aattattaaa attaaagaga agttccgttt 388560
aacaaatgat gaatttgctg ctgtacgttt taaaatagaa gattttgtac ctgctattcc 388620
tcaaaaattt gcagatattg aagaacgctt tgttcaatta gaagcattga tgaatagtca 388680
gcgttttgat gaagctaaag tatcagcaga taaaattgat aaagacattg atttattaag 388740
tgcttatctt cgtgatttac caacttatat ttcaattgtt cgaaaatata ttcctaagcg 388800
attagatgaa ttataccgtg ttattactga aatgaaagaa cgtgattttt caattgaacg 388860
tcttaataca acagttcgct ataataagat caatgctgat ctagaaaata cgatccaagc 388920
tattaaagag ttaaatctag aaaatgttgg tgcttccatt gaagtaatga cagaagatct 388980
aaattcttta acggcagact ttgaaaaaga ggaagctgca tatagtcgct atgaggaatc 389040
acgtaatgct tgttacaaac atattgggca tttagatgaa ggccttcgaa atactattaa 389100
ttctttaggt gaacttcaaa ggaattattt attatctgat tatgaaatta ctgttaaaga 389160
agattatgag gcttttaaag ggattttaga tgaattagat caattaacag taataattga 389220
aagcaatgat ttttcatata gtgtcttgat tgagcgtttt gaagaattga ttgatcgttg 389280
taaacctttt gatgagtctt tgaataagta tattgaatta gaaaattctt tgagattaca 389340
agaaaaacgt gctttagatg agttagataa tattaatatt gtcttactag aaataaaatc 389400
ggagattaaa aataaacatt taccaatgat taatgaatct tataaagatt atattgatga 389460
ttcttatcaa aaagcggatg aaattttgaa atttatcaga cgtcgaccaa ttgatttaga 389520
gcgtctctca gttcaagttg atgctgcacg agatgtaatc tataaattat atgataatgt 389580
tcataatttg attgttactg cagaaatggt tgaagatgca attatttatg gtaatcgtta 389640
tcgtagttct tttttagaag ttaacacaga attaactaaa gcagagctgt tatttagaaa 389700
tggtgaatat actaaagctt tgactactgc agtagatatt attgaaaaaa tcaatcctgg 389760
atcatatgag atgttgatta ataaaaatag tgcaaaatca taagattttg ccttttttta 389820
tgggtgagag tataattatg aagaatgtac aaggtattat agtttaaaag taatataatg 389880
gggatattaa agcttattaa taaaaatagg agataaaaat gaaaaaatta ttaatttggg 389940
gtgcaggaga tcaaggactt gtgactcttg agtgtgcttt agccatgaat gcatatgaac 390000
aaattgattt tttagaaatc aaagaaaaag gaagtagaaa aataattaat catactgtat 390060
ttaaagaaag tgaattcgat aaagtagtaa aattatatga tgaggttatt gttgcaactg 390120
gtagcaatga tttacgagaa gaaaaaataa aaatgttact tgcttttggt attcctttag 390180
caacgatagt ccatccaaca gctttaatta gttcatctgc aaaaattggt agtggtacaa 390240
cgatattggc taatgtaata attaatatta atacaaaggt cgggattggc tgtatagtca 390300
ataatggagc aattattgaa cacgattgta tggtaggaaa ttatgttaat atttgtccta 390360
agtttgcgat ggcaggtcac agttcgattg gatataaatc ttatctggga ataggtagta 390420
ctgtcattga tgatattaga attggtaatc gggtaacagt tggtgctgga gcggtagttg 390480
tttcaaacat ttctgataat atcgttgcga ttggtgttcc agctaagaaa atgctggtgg 390540
ataagtaaaa agtgttgtgt taaaatattt aagataatta caatttgatg gtttacgttg 390600
gttttataaa agtaattata taggaaaatt aaagtacttt ggaattgcaa gtaagaaaat 390660
gattttattt ctttactttc gtagtaaata ttgtagaatt atttaatgtt gtttgaaaga 390720
tattttggtg gagtcataag actttggatt tttattgcat ataataatgt agggggttac 390780
gatgatatat ttagattatg tggcaacaac gccattaaat tcagaagtgt taaatactta 390840
tcataattta ttatccaatt atttttataa tgctgattca atgtatgata aaggtattga 390900
ggtaaatcgt ttgatggaac attcacgtaa attaattagt gagtccttca aagttaaaga 390960
agatgaaatt atttttacta gctgtggtag tgaagctaat aatatggcaa ttaaaggtac 391020
agcctttcaa tatcaaaatc gtggtaaaca tattattact acagctattg aacattcatc 391080
tgtttatgaa acttgtaaag agttagaaaa gttttttgga tttgaggtaa cttatttagg 391140
ggttgatcat aaagggcgga tttctttaga agaattagaa aaaagtattc gtgatgatac 391200
gattttagta tcaattatgt atgtaaataa tgaaattggg gtcattaatc ctattgatga 391260
aattaaaaaa attgttaaaa aatacgataa ggtaaaactg cattttgata tggtacaggc 391320
tttaggaaaa ttaccaatcg atttaaatga tgtggattta gcttcttttt cggcacataa 391380
aatttatggt ttaaaaggta gtggcttatt attcaaacga cgttcaacga caattgttcc 391440
tttaattagt ggcggacaac aagaatttag tttacgaggt ggaacttcta atgcctgtac 391500
taatattgtt tttgcgaaaa ctttaagatt agcattagat aattttgaac aaaaaaatca 391560
acatattaaa gatataaatg attattgtcg aaaatgttta caggagatag aaggaattgt 391620
tattaatagt gatgaaaatt gctgtttacc atcaattttg aatttctcat gcttaggtta 391680
taaaccagaa gttattttac atgatttgga aacaaaagaa atatatttat caacgcgtag 391740
tgcttgttca tcaaaaacga gcaatgtttc acgagtcatg gcgcaattac atttagatga 391800
agcaattagt tctagtgcgc ttagaattag ttttggagag catactacaa gagaagaaat 391860
cgatcggttt tgttattatt tacaagaaag tatgcgtaaa ttaaagaagc agaggtagaa 391920
tatggaagca aattatattt tagtacgttt tggtgaatta acaacaaaag gtaaaaaccg 391980
taaattattt acgaatcgtc ttttaaaaaa tactaaggag atattagcag aatttaatca 392040
tttaacatat gatttacaac atgatcgtat gtatgttgtt ctaaatggta ctgatcatga 392100
agctgtatgt acgaaattga aaacagtatt tggaatctat tctttttcag tagcatataa 392160
aatggaaaaa aatctcgaat tagctaaaca agcggtttta caaataattg aaaacaatga 392220
tgggaatacg tttaagatta atactaaacg ttcagataag aatttccctg gaagttctca 392280
agaaattaat cgtgaaattg caggatatgt atttcatcac actacaaaag aaataaaagt 392340
tgatgtccat gctccagcaa ttttagtaac agttgaaatt cgttatgacg cgatatatgt 392400
aatggataat attattaaag gagcaggtgg gtatccagtt ggagttggtg gaaaagcatt 392460
attgatgatg tcaggaggaa ttgattcacc agtagctgga tatttaacat taaaacgcgg 392520
tgtagatatt gagtgcatcc attttgctgc accaccttat actaatgaat tggcacgaga 392580
aaaagttttt gatttagttg ataaattacg tcattatact cacggttcaa ttagagttca 392640
tgtaattaat tttacaaaat tgcaattagc tgtttatgat aattgtgacg aaagttatgc 392700
aatgacagtc atgagaagga tgatgtatcg tattagtgaa aaaattgcta ataaaaataa 392760
ttgtcttgca ttagtcaatg gtgaaagcat tggacaggtt gcttcacaaa ctttaaatag 392820
tatgcaggta atcaatgaag ttgttaagat tccagtacta agaccagtat tatgtcttga 392880
taaattagaa attattgata ttgctgatag gatcgatact tatgaaattt cgattcgccc 392940
tcatgaagat tgctgtacta tttttacacc taaagctccg gcaactaagc ctaagttata 393000
taaagcggaa atatttgagt ctgggtttga ttttgaaact ttgattgatg aatgtgtaga 393060
aactgctgaa attattacag tcgatcacaa ttataagaaa aacgacgata ttttttaaaa 393120
ataattaaaa aagcgtatat ctttttttgt ttgacacaag atattagtgt caggaggtga 393180
agatatatgt cacaaagtaa ctctagtaga aacaaattag ttgttcctgg agctaaaaat 393240
gcaatcgatc aaatgaagta tgagattgct aacgaatttg gcgttaattt aggtcctgat 393300
acaactgctc gtgataacgg ttcagtaggt ggcgaaatca caaaacgatt agtcgctatg 393360
ggtcaagcac aaatgagctc atcaaacaaa tacaatcaat ctaaataatt atttttaaaa 393420
ccctagttag ctagggtttt tatctttaaa aaataaattt aaattttttt attaaaaatg 393480
tatattttaa aacaaatgac acaaaatatt actgtcagga ggtgaaaata tatgtcacaa 393540
aataactcta gtagaaacaa attagttgtc cctggagctc aaaatgcaat cgatcaaatg 393600
aagtatgaga ttgctaacga atttggcgtt aatttaggtc ctgatacaac tgctcgtgcg 393660
aatggttcag taggtggcga aatcacaaaa agattagtcg aaatgggtca atcacaaatg 393720
agttcatcta ataactacaa tcaatctaaa taattatttt taagacccta gttcaatcta 393780
gggttttaaa atattcttaa atataaaaca aatttattcg ataattccaa taaatacttt 393840
aataaatggt gaaagtgctt tcaaaatata ttgagtttag tgttgaattt aggtacaatt 393900
aatatatgac atgaagaaat aggaggaatt ataatggtta aagtaatggc aatcaatgct 393960
ggtagttcat ctttaaaatt ccagttgatc aatatgccta gtgaagaagt aattacatca 394020
gggttagtcg aaagaattgg actagaccaa ggtaacttcg aaatgaaata taatggtgaa 394080
aaatttatta aagagtgtcc aattaaagac catagtgttg cagtacaatt attattagat 394140
gctttagttg atcaccatgt tgttgaaagt ttaggtgaaa tcgaagcttg tggacatcga 394200
gttgtccacg gtggcgaata ttataacgac gcggttaaag tcgacgagga agttgttgct 394260
cgcgtagaag aattagctga attagcgcca cttcacaatc cagcacatat tgttggatat 394320
aatgcattta aagcagcttt accagaggtt gaacatgttt ttgtatttga tactgcattt 394380
catcaaactc ttgatcggga aagatattta tatcctttac catatgaata ctatacagat 394440
ttaaaagttc gcaaatatgg tgcccatgga acaagtcata aatatgtatc tcaagttgcc 394500
attgatatgt taggaaatcc caaacattcg cgagtaattg tttgtcattt aggaaatggt 394560
gcaagcattt cagcagttca ggatggtata tgtattgata cttcaatggg atttacacca 394620
ctggcaggag taatgatggg aacacgctgt ggtgatgttg atccatctat tatgccgtat 394680
ttatgtaaaa aattaaataa aacacctgat gaaattttag atatctataa taagaaatca 394740
gggatgttag gaatttctgg aatttcttca gattcccgtg atattgaaaa tgcattattt 394800
aagaacggtg atgaacgtgc acttcttaca ggcttgttat atgcacgaat cgtttcaaaa 394860
tatattggaa gttattttgt tgaaatgggt ggtgttgatg ctattgcctt tactgctgga 394920
gttggagaaa atgcttctta tcttcgtcgt ttgatcattg ataatgtttc acgtgcgtta 394980
ggcgttttct taaatgaaga agaaaatgaa cgtcgtagta aagaaaatcg tctaatttcc 395040
catcaatatt ctaaagttga tgtttatgta atccctacta acgaggaagt aatgattgct 395100
cgtgatactg taagaatttt aggtttataa gctctgatca ataatcagag cttttctatt 395160
tataaatttg ggtaaatatg gtatagtcat cttattaaat agaggagttt tataatggaa 395220
gaaaaaataa ttgctaaaat tgaagaatat gattatattg ctatttaccg tcatgtaaat 395280
ccagattttg atgcttttgg cagccaattg ggaatgtacg atatgattaa agctacttat 395340
ccagataaaa aggttttttt atgtggtgat ttcagttcgg aattagtgaa aaaatataca 395400
gtagtttttg aacatcaaga agttgattat actaaagata ttttaggaat tgttcttgat 395460
actgctaata ttgaaagaat tgatgatcaa agatatcaac tttgtaaaga aattattaaa 395520
attgatcatc atttggtcgt agatagttat ggcactttaa attacgaaga tagtagtgct 395580
agttcagcta gccaattagt tggaacaatt tttaaagata cggctatgaa aattactaaa 395640
agtggtgcag aagctttgta tttgggaatt gttggagata cagcgcggtt tatgtatcga 395700
aatactgatg aacggacttt tgcagtagct ggagctttgg ttcaagaagg aattgatatt 395760
gttgaaatct ataatcgaat ttatatgaag aaggctaagg atttacaaat taataaattt 395820
attttaaata atcatcagtt tgatggtggt gttgcttatt atgttttaag tgatgcagat 395880
ttaaaaatgt tagaaattag tcgtgaaaga ggttcggatt ttgttaattt attatctggt 395940
gtagaagaat ataaaatttg gatggctcta actgaaaatg tcgctgatca taattggcgt 396000
gttagtttac gttcacgtga ttacgcagtc aataaggtgg ctgaaaaata taatggtggt 396060
ggtcatatgc tggcaagtgg cgcaaagtta gcttcattag aacagcttgg tcaactgctt 396120
caagatttaa aggagataat caatgaataa atttactgac atatttgcaa attttattga 396180
gggtttttca tttagacaag gttctcaaga tgtaaaacaa gtaaaaaaag gtgctttttt 396240
aaaggcgttt acaataactt taataattgg attgattggt gaatatgctt ttttgatccc 396300
attgaatctt cgttcaccac aatttataat ttatttttgt atattattat taatatttaa 396360
tggactatat tttatgttaa gtcaaagatt tagtaagatc accaaatata gtctcattgt 396420
gattggaata ttaattgcat atgtggccat tggaacattt gttagttcgc ctatctttaa 396480
tgcaggaagt tatcaaaaac aattaaagtt agataagaaa gcagacttct atgctgacaa 396540
taaaactatt tcctatcaat cgattccagt ggtggatcga gatagtgcga ttaaattagg 396600
tgatcgtaaa atgggacaga tggttgatta tgtatcccaa tttgaggttg atgagtcgta 396660
tgaacaaata aattatcaag atacgccata tcgtgtgaca ccattagaat atagtgactt 396720
gatcaaatgg tttactaacc gtagtgatgg actgcccgca tatatccgag taaatatggt 396780
gacgcaagaa tctgaagtag ttaaattaaa agaaggaatg aaatattcta aatcagaaca 396840
ttttggacgt aaaattgaac gtcatttgcg cgctaattat ccaactttaa tgtttgatac 396900
attggctttt gaaattgatg aaaaggggaa tccttattgg attgcaccag tatataatta 396960
taaaatcggt ttatttggtg gaaaagatat aactggagct gtattagtta atgcaataaa 397020
tggtgatcat gaatattatg atattgataa agtaccagaa tgggttgacc gtgcttatcc 397080
agcagaactg gttttaagtc aattagaaaa ttatggtaaa tatacaaatg ggtattttaa 397140
tactttattt tcgcaaaaag gagtattaca gccaacctct ggttacaatt atgtagcaat 397200
caatgatgat gtctatttat atactggttt aacatcggta tctaatgatg cttctaacgt 397260
tgggtttgct atgattaatt tgcggactaa agatggaaag tattataata tttctggagc 397320
tgaagaatat tctgcaatgt cttcggcgga aggtcaagtt caaaacttga aatatacggc 397380
aactttcccg attttgatca atgcgggagg gcagccaaca tatttcttat ctttaaaaga 397440
tgatgctaaa cttgttaaaa agtatgcttt tgttagtgtt gaaaattatc aaatcgtggc 397500
taccggtgac agtgttgctc aagctgaaca agcatattat gctttattag aagctaatgg 397560
taaaaaaact gactcaagtg aatataagac taatgagttg actggagcga ttactgcaat 397620
taatgaagct gtcgttgatg gtaacagtac ttattacttt aaacttgaag gtagtgatac 397680
gattttcatc ggagatatca gtttatctaa tcaattccca ttagcaaaag ttggtgatgt 397740
tgtaaccatt gaatatgtta atagtaaaga caatagcgag gtaattactt caattaaatt 397800
tggttagtct ttaatagaac aagaagctat aacttatata taggttatgg cttttttata 397860
tttattatca tctctttaaa ctcaagctat tttgcttttg taactatata tttagttaat 397920
aaaatgtgtt ataatcttac agtgaattga ggtgtaaaga tgaaagcaaa agtactagta 397980
gttgatgatg aaaaagatat tagggaatta attaattttt atttgaataa agaaggattt 398040
gaagttctgg aagctagcaa tggtgaagag gctttagaaa tattcgaaaa tgaatatatt 398100
gatttaggaa tcattgatgt catgatgcca gttatggatg gttttgaact agtagaaaat 398160
ctaaaggaat ttaaagatgt tccagtaatt atgttaacag cgaaaggtga aagtaaagat 398220
aaacttcgcg gtttttctgt tggtgctgat gactatgtag ttaagccatt tgatccaact 398280
gaattaatgg cacgagtgcg agcagtttta aaaagatata gtgttaatac atcaaatata 398340
atcaaattaa atgaagttga gtttgatggc gataaatatg agatacgtta tcagagcgaa 398400
atcattcatt taccgttaaa acaatttgaa ttagtttttg agttagcaaa gcatccagat 398460
cagattttta gtcgtgaaca gttgattgaa aaaatttggg gaatggacta tgatggcttt 398520
gatcgtactg tagatgttca cattaagcga attagagaaa atctaggaca cttaccagga 398580
tttaaagttg taacggtgag aggacttgga tacaaggttg aagtcgaatg atgaaatcta 398640
tttatggcaa gctgatttgc ggttttttaa taactatcgc atttagtttt tcggttgctg 398700
gatatgtagc tttacgtaat aattatgatc aaattgaaga tatggctaag agtgagttga 398760
gtgcaacaag tgaatatgtt gtaggtattt taaatagcct tgatgatgct aatattaacg 398820
atattatgaa taaatacgca attagctcag aggtttatat aacgttgtat tcaccagaat 398880
tggactatta tacatatggt gaaaacaaag gatattttcc tagtcgcgag acaatgattc 398940
aatattatca tgatgaaaac aaaaacgggc gtttcgatga gcgcaaaagt gtgcaaacct 399000
atggcagcaa ggcaaaaatc aatggttctg atgtatatat atttattcaa aaggatacta 399060
gttatgaaaa aggaattttt gctaattctg ctgttttgat tttgggttgt gtctttttat 399120
caggaaatct agttttttta gcgattgctg atattattgt taaaccaata acgagattaa 399180
ctaacgccac taaagaatta tcaaaaggaa attatagtgt tcgtgttaat tatgtgggtg 399240
atgatgaaat ttctcgattg aatcagggat ttaatcaaat ggcacagcag ttagcgaaac 399300
aagaagaaac aagacaaaag ttcatttctg atatttcgca cgaatttcaa actccattga 399360
ctgcaattca aggctttgcc aatattttaa aagaggaaga tcttcctaaa gagcagcgtc 399420
aaaagtatgc tgatataatc ttatttcatt caaaaaggtt atcgactctt tctaagaata 399480
tgctgcagct gacgttgttg gaacgagaag aggttgagtt agaatttaca acatattcaa 399540
ttgttgagca attatctcgg gttatttcta ctcaagaaaa ccaagcaatt ttaaaggata 399600
tagaaattca atttgaaaaa ccgcgcaaag atattatggt ttatggcgat gaacaacgat 399660
tggaacaagt ttggatcaat cttatttcaa atgcaatcaa atatactggt gaaggaggtc 399720
ttattacagt aactgttaaa aaggcttctc gtgaagttga agtatcaatt gaagatactg 399780
gatacggaat gtctaaagaa gttgtttcac atatatttga acgtttttat cgtgaagaaa 399840
aagcccgttc tgtagaagga aatggactag ggttatcaat tgtaaaaaca attgtagatt 399900
tacatcatgg aaatatagat gttatttccc aggttgatgt tggctctact tttgtagtaa 399960
aattaccaag cgaacgaaaa gtttttgata ttaaagaaaa actatcgttt aataaataat 400020
cggaggaatt tatggaatta cttaaagaga gaatattaaa agacgggatt gtaattatgc 400080
cggatatatt aaaagtggat agttttttga atcatcaaat tgatcctact ttgtatcgac 400140
aaatagctca agaattcaaa actcgtttta aagacacaaa aattactaaa atcttaacaa 400200
ttgaagcttc gggaattgga attgctttag caacagcttt tgaatttgat gatgcacctg 400260
ttgtctttgc aaagaaaggg actgcaaaaa caacaagtac acattattat agttctaaag 400320
tacattcatt tactaaagga attgattatg atgcgattgt cagtaaaaaa tatttagata 400380
aagacgataa tatcttaatt atcgacgatt ttttagctaa tggtcaagct gtattaggtt 400440
tagttgatat tgttaaacaa gcaggtgcaa atattgctgg tgttggaatt gttgttgaaa 400500
aaggttttca aacaggtcgc caattaattg aagaaaaagg ctatcgtgtg gaatcgttag 400560
cagtagtaga agcatttagg gatggtgcgg tgatcctgaa ataatgagag gaagaaagta 400620
atgtatttaa aaagaattga attacatggt tttaaatcat ttgctgataa agtcaatgta 400680
gaatttcaac ctggaatcac aggaatcgta ggtccaaatg gttgcgggaa atcaaatatc 400740
tctgatgctg tacgttgggt tttaggagaa cagtcagtta aatcgttgcg tggtgcaaat 400800
atgtcagatg ttatttttgc tggaagcgaa gatcgtcggg cacaaaattt agctgaagtt 400860
accttagttt tcgataacag tgatcgtttt atgaaatatg attataatga agtcgagatt 400920
acacggcgac tttatcgtat gaataatgaa gcggagtatt taatcaataa acaatcttgt 400980
cgtttaaaag atattattga tttgattatg gatacaggtc taggaaagga ttcgttatca 401040
attatttccc aaggtaatat ttcttctttt gcggacaata aaccagaaga acgtcgtggt 401100
atttttgaag atgcagcagg agtttctaaa tataaaaaaa gaaaattaga atcgattcgt 401160
aaattagaac gtactaacga aaatcttgaa cgaattggtg atatcgtagt agaactagaa 401220
aaacaggttg gtcctcttaa acgtcaaaaa gacaaagcag agaagtattt agcgttgaaa 401280
gaaaaattaa cagctataga agttaatgtt ttaataaatg agataactga agcaaaaaaa 401340
tcactagatg aattgagtaa ggtaatcaag gacttaaatg agcgtcaagc ttctttagag 401400
gctgatattt tgcttaaaga gagcagtaac gatgaaataa aaaagaaaat gtttactctc 401460
gaccaagaaa taaatgcttt acaaagtaaa ctattagagg cagtatcaaa tgtctcgaaa 401520
ctagagactg ccaaagtcga agttgatcaa aagcgaaaac atgcacttga gaccttaagt 401580
aaagaaaatt taaaagaaaa tatcgctaat atgaaggcga ttttaagtga tgttgttaat 401640
gaatataatg atcgtgtgga acgattagat aacactcaag aagagttaac cacgataatt 401700
ggacaacaag aggagcgtaa taaaaaatta cttttattaa aaaatgaaat tgatcaatta 401760
tcaaacaata ttaataaaaa taaatcacga aaagagattt taatagatgc gattgaaaat 401820
aaatcaaatt atcatcatgg cattaaaaca gttttaagtc ttgctaaaag taataaaaat 401880
attattggtg ttttaggtga tttaattaca actgatgaag gatatgaatt agcgttgtcg 401940
tcagctttag caggagcaat agagtttatt gttacaacag atgatttaac tgcacgagat 402000
gcaattaaat ttttacgtga taataaagcg ggacgagcta cttttttacc aatcagtgct 402060
atgaaaccac gacatgtgcg tgaagaacat ttagttgttt gtcaaaccat ggaaggatat 402120
ttaggtttgg ctagtgattt tgtaacatat gaagatgaga ttgctgccgt tgttttaaat 402180
caactaggga atatcattgt agctaaagat attgatagtg ctaatgaaat cagcaaagca 402240
actttttctc ggtacaaagt cgtttctctt gaaggtgatg ttgttaatgt tggcggttct 402300
ttgacgggtg gaagttttaa tcgtcaaaaa tcttcaatag ttcaaaaacg tgaacttgag 402360
caggttgctg ttactcttga acaacaagaa aaagaacttg ggcttaagcg taatgaacat 402420
aatggattgg ataatgaaat caaagaagtt tcacatgctc tattacaaaa gcagatggca 402480
tatgctaaat tggaagttgt tgttcaaagc aagaaagaag agttgatcaa ggcaaaatcc 402540
gagtatgaat cattagctga tcaaagtgtt gaattagaag aatttgctag tggaaaaaca 402600
gaaagtaaat tagttaatca gttaaatgaa gcgattaaat atcgtgataa tttaactgaa 402660
gaaattaaat caaaacgtga acttagaatg gcctatgtta atcaaaatga agctttagat 402720
gttgaattgc gtgaatatcg taatgattta aaagaggttc aaagtgaggt taatactagt 402780
gctattaatg caacaaaatt agaagcaatg ttaaataatc atttagctag attaaatgat 402840
gaatatcgga tgacttatga gtatgctgtc gagcattacc ttgatgaaat tgatgttgaa 402900
caagctaaat tagaagtata cgaattaaga acaaatatta atcgtttagg aaacgttaat 402960
gttgatgcaa ttgaagaata tcaaataatc agtgagcgtt atgagaacat gaatactcag 403020
cgtatagatt tgattcaagc ccaagatagt atccttgaag cgattaaaga gatggatgaa 403080
attatggttg agcgtttttc agaaacgttt gagaaaatca acgaagagtt caatcatgtc 403140
tttaggagtt tatttggtgg aggaaaggct agaataaagt atactgatcc tacaaatatt 403200
cttgaaactg gaatcgatat tgatgttcag cccccaggta aagcagtcca gaatattaca 403260
ttattttcag gtggggaaaa ggccttgatc gctatttcat gtttatttgc aattttacgg 403320
gtacggccaa ttccgatgtg tatcttagat gaggttgaag ctgcattaga tattgcaaat 403380
gttgaacgtt ttgctaaata tttaagagaa ttttcgggaa cgacgcaatt tattgtggtt 403440
acccatcgtg aaggaacaat ggaagaatgt gaccttcttt atggagcaac aatgcaacaa 403500
aagggagtta caaagttagt tagtgtcaaa ttagaagaag caatagattt aacagatcaa 403560
agttaggagg aatcgtatgg gattttttag tcaaataaaa gaaaaattcg ttggtaaatc 403620
tgctaaacaa aacgaaaaat atgtagctgg attagatcgg tctaatagta ctttttcaga 403680
tcgaatcaat gaacttgcag ctcgctttag agaaatcaat gatgagtatt ttgaagaatt 403740
ggaaaatatt ttgattatgt ccgatgttgg agtttcgatg gtaatgaaga tagttgaaga 403800
aattaaaaac gaggtacgtt tgcaaaatat tactgaccca aaagagatta atgagatcat 403860
cgttgataaa atgttcgtta tttatgcaaa tgatagtgtc atgacaacta agattaacta 403920
tgctgaggaa ggattaacag taattttaat ggttggagta aacggggctg gtaagactac 403980
aacaattggg aaattagcta atcgtatcgt taatgatgaa ggtaagaaag taatggttgc 404040
agctggagat acttttagag ccggagcgat tgatcagtta gcagtttggg cacagcgtgt 404100
tggtgtcgat attgttaaag gtaaagaggg cggtgatcct tcagcagtgg tatttgatgc 404160
tttaaaacag gcaaaagaaa aaaatgttga tgttttaatt tgtgatactg ctggtcgtct 404220
tcaaaataag gtcaacttaa tgaatgaatt agaaaaaatg aatcgtatta ttaaacgcga 404280
agtacctgat gcaccgcatg aaacactgtt agttattgat gcaacaactg gtcaaaatgg 404340
tgtttcacaa gctgtggaat tttctaagat cactgatgtc tcagggttag ttctaaccaa 404400
aatggatgga actgctaagg gggggattgt tctttctatc aaagatcaat tgaatatacc 404460
tgtaaaattc attggtctag gagaaagtgt tgatgattta caagaatttg atttagacca 404520
gtatatatat gggttatgca aaaacctagt tgaggaatag tatggaatca agtttagaga 404580
aaaaacaacg agttaatcta ctaatggatt gttatagtga tttgttgaca gaaaaacagc 404640
aaacatattt agaatattac tatcaagaag attactcttt atcggaaatt gcacaaattt 404700
tggatgttag tcgtaatgct gtatttgata atttaaaaaa agcagttcat agtttagaaa 404760
attatgaaga aaaactgcag ttgttaaaaa aacatcaaga aaggcttgac ttgatccaaa 404820
gaattgaaga tgatatatct agtgatcata aaagtctaga agaatattta gaattattaa 404880
ggaagattta gaaaggggta tttatggcat ttgattcatt atcagaacgt ctgcaaggga 404940
ctttaaagaa agtttctgga caagggcgtt tgactgaaaa aaatatggaa gaaatgctta 405000
gcgaaattcg cttagcatta ttagaggcag atgtaaactt tcaagttgta aaagagttta 405060
ttgctgcaac aaaagaaaaa gcgttgggac aagatgtttt aggttcatta aaaccgggac 405120
aggttgttgt aaaaatcgtc catgacgaac tagtttcgtt actgggaaca agtgttgcgg 405180
aagttgattt tgataagaag ccaactgtta ttatgatggt tggacttcag ggttctggga 405240
aaactacaac ttctggaaaa atcgcaaaat taattaccaa gaaatatggt aaaaaaccat 405300
tgttggttgc tgcagatatt tatcgcccag ctgctgtgga tcagttaaaa acattaggtg 405360
aacaattgaa tgttcctgtc tacgaaaaag ggacatcaca atctgctgaa tcaatcgtag 405420
aagaagcgat gacatttgct cgtgaccata ataatgacgt aattattatc gatactgcgg 405480
ggcgtttaca tattgacgaa ccattaatga acgagctggc taatattaaa aagatcgctc 405540
atccaagtga aattttacta gttgttgatg ctttaactgg acaagatatt gttaatgttg 405600
ccagttcatt taatgaacag ttgagcatta ctggggctgt tttaactaaa ttagatggtg 405660
actctcgtgg tgggggagct ctatcaattc gtcatattac aaatgtacca attaaattca 405720
ttggtactgg tgaaaaatta gatgctatcg atttattcta tcctgatcgt atggctgatc 405780
gtattttggg aatgggcgat gttgtatctt tagttgaaaa agtacaagat gtatatgatg 405840
aaaaagatac aatgaaagcc tataaaaaga tgcaatcggg acaatttggt cttgatgaca 405900
tgctttctca aatgcagcag ttaaggaaat tggggccact atcaggaatt atgaaaatga 405960
ttccaggaat gcctaagtta ccaaaaatga atgatgagga ctctgaaaag aaattaaaaa 406020
tgactgaatc aattatcttt tcaatgacca aagaggaacg tcgagatcca agtattatca 406080
ctttatctag aaaagagaga attgctaaag gttgtggtaa agatgttgca gcagttaacc 406140
gcttgctaaa acaatttgaa gaatctaaaa aaatgatgaa gatgttaggt aatgttgatc 406200
ctaatacagg tatgccaatg ccagggggac gtgcaaagaa ccctaatatc ggtaatccta 406260
atcgtaaaaa aatccgtcat aaaaagaaga aaaaatagcc tgataaattc aggcttttta 406320
ttactaaagg agaatatgaa tgactcaaaa taaatatgat gatccagctt tttttgaaaa 406380
atatagtcag atgtcgcgga gtaaaaatgg attagagggt gcaggagaat ggcatgtatt 406440
acaacgagtt ttacctgatt ttacaaataa aacagtattg gatttaggtt gtggatatgg 406500
ctggcactct atttatgcga ttgaacacgg tgcaaaaaaa gttatcgcaa gcgatatttc 406560
tagcaaaatg attgaaacag caagaatcaa aaacaatgat ccgcggatta aatatgaatg 406620
catttcgttt gaagaaagta attttggaga agctgtattt gatattgtta tttgctcttt 406680
aatgattcac tatttacctt cctaccaaga ttttgtaaaa aaagtaaata aatggttaaa 406740
aacaggtgga tatttggtgt ttaatgttga acatcctgta tttactgcta aaggagatca 406800
agactggtat tataatgaag ctggtgaaat tgagcatttt cctgtagata attattatct 406860
tgaaggaaaa cgtgaggcgg tgtttttagg ggaaaaagta attaaatatc atcgcacatt 406920
gacgacttat ttaaatgaac tgttaaatgg cggatttgaa ataattcaag ttaaagaacc 406980
aacggtaagt tcaaatgccc ttattgcaca tcctgagttt aaggatgagt tacgccgccc 407040
gatgatgctg attgtttctg ctagaaaaaa ataaacactg tcaagtaaaa aagcttgaca 407100
ccttatctag agtatgataa atttagtgag taaattaatt aggaggatat gtatatggca 407160
gtaaaattaa gattattaag aatgggtgct aagaaagctc ctttctatag aattgtagca 407220
gcagattcaa gagctccaag agatggacgt tttattgaac tattaggaac ttatgatcca 407280
cgcactaacc ctgcaaaagt tacaattaaa gaagaagaag tattaaaatg gttaaacaat 407340
ggagcacaac catctgatac agttaaaaac ttactatcta aagaaggaat tattaaaaaa 407400
tttgctgatt ctaaatcagg taaataatca tggattacgc aaagattctt aaagatatcg 407460
cgattgaatt agttgaagat aaagaccatt tagaagtacg tgaaatgccg tcgttagaag 407520
aagatgtagt ggtactacat gtttattcag ctaaatcgga tattgcgcga ttgattggtc 407580
gtaaaggtat gatggctaat tcaattagac agcttatgtc tgttgctggt cgcatggcca 407640
ataaaaaatt agatattaag tttgaatcgt atgaacaata aaagatgtgc tgagcacatc 407700
ttttattata tggaggacta atggaaaaac ttaaaattgg aaaaatagta ggaacacatg 407760
gcttaaaggg agaactaaaa attagatcaa atagtgattt tgctgataaa agatttaaaa 407820
aaggaaacga aattattata cgttatcaaa atcaagattt ggtctataaa attattacat 407880
cgcggataca caaaggaaat tatttagtat catttaggga taatcaagat attaatttgg 407940
ttgaaaaata tattggttct tttgtttatg ggtataaaga tgatgaactc ttagatgctg 408000
atgaatattt ttatacagac ttaattggaa tgcaggttgt ttctacagag ggaacaaaaa 408060
ttggtccagt tacttcaatt tatgataata ctcgtcatga tattttaaat attgatcata 408120
atggtaaaaa tgttgcaata ccgtatgttg atgcatttat taaagatgtt gatgtagaaa 408180
agaaaattat tgtagttatg ctaataaagg ggcttattga tgaagattga tattttaaca 408240
ttgtttccag aaatgtttac aggtttttta aatacgtcga tcatcaaaag agcgattgac 408300
aaaggtttag ttactattga attacatgat tttagagagt tttctattga taaacataag 408360
catgtcgatg attatcctta tggcggagga caagggatgg ttttaatgtg tgcaccaatt 408420
gttgaatgtc tcaaaacaat tgcaactgat gatagtttta ttatcttaat gtcacctcaa 408480
ggcattactt tgaatcatgg ttgtgctgta gaattgtcag ctaaaaaaca tttaattatc 408540
atttgtggtc attatgaagg ttttgatgaa cgaatccgtg attatgttga tatggaatta 408600
tcgattggtg attatgtttt aactggtggt gaactaggaa gtatggttgt tagtgatgca 408660
gtgatacgct tattagatgg agcaatcaaa gaagacagtc atatggatga ttcttttagc 408720
catggactgc ttgagtatcc tcagtatact cgcccacaat gctatgatgg taatgaagta 408780
cctgaggtac taatgagtgg gcatcatgaa aatattcgca aatggcgcaa gttccaatca 408840
ttaaaaaaga cctatttgaa acgaccggac ttattggaat cgtatcaatt tgatgctgaa 408900
agtatcgaaa tgatgaaaaa aataaaagaa aatgattgat ttttatgatt gattagtcta 408960
taatgtaaca gtcgcaagac tgcagatgtt ccgctggtta atcgaatgaa cgtttaagac 409020
aaaattttga taaggagaaa tagtaatgaa tttacaatta gtagaacaaa tcactaaaaa 409080
acaaatgaga aatgatattc ctgagttcaa agcaggggat acattaaaag ttttcgtaaa 409140
aattaaagaa ggtgaaaaat tccgtattca gttatttgaa ggagtttgta tcgccagaaa 409200
aggtagtgga atttctgaat cttttacagt aagaaaaatc tcttaccaag ttggagttga 409260
aagaactttc cctgtccaca ctccaattat tgatcatatt gaagttgtta aagttggtaa 409320
agtacgtcgt gctaaacttg gatacttacg tggattatct ggtaaagctg ctagaattaa 409380
agaaattaga aaatagaaat ggctcgccat ttcttttttt tctaattttt tgtataatag 409440
acataatgta ggaggacttt tttatgtcaa agaaaaaaga agttatcaag ttttcactac 409500
aactattggc aatcgttgca gttacaactg taacctttac taaaataatt attccggtga 409560
gggttgatgg tcaaagtatg tatccaactc ttcatgatga agatattgca atagtaaatg 409620
cgttatcact tgagcgaagt gatataaaac gttttgatat agttgtattg aaatgtgaaa 409680
aattggataa ggatattgtt aaacgggtaa ttgggttacc tggtgatact cttgtttata 409740
gagatgataa actatatatt aatggaacat actatgatga aaagtacttg aataaagatt 409800
atatcgcaaa agctaaaata aaatatcaaa cggaactatt tactaatgat tttgaaatca 409860
cattaaatga cgatgagatc tttgtattag gtgataatcg gttacaatct gctgattcta 409920
gaactttagg tacatttaaa tatagtgaca ttataggcaa aaaaggttta gttattttcc 409980
cgttaaaaaa tatgaattta attaagtagg aggtttaaaa tggtaaaaca gattcaatgg 410040
tttcctggac atatggctaa agctcgtcgg gaaattagtg aaaaaatgaa attgattgat 410100
atagtgatag agcttgttga tgctagggct ccactatctt caaaaaatcc aatgtttaac 410160
gaaatttgta ataataagcc aaggttgatc gtaatgacga aaaaagattt agcggattct 410220
aaggcaacaa gtaagtggat tgagtatttt aagggaaaag gtatttatgc aatttgtgtg 410280
aatttaaaga attttaatga atatcagttg gtcattgatg tatgcaaaga aatattgaaa 410340
gaaaaaatgg aacgtgaagc taagcgggga ttaaaaccac gggcaatgcg agcaatggtt 410400
ttaggaattc ctaatgttgg gaagtcaact tttataaatc gtttagcaaa aagaaaagcg 410460
acagtaactg ggaatcgacc tggggttact aaagctcaac agattataag agtagacaaa 410520
gattttgaat tattcgatac gccgggagtg ttatggccga aatttgatga tttgaatgtt 410580
gctcgaaaca ttgctttgat cgggtcaatc aagcaagata tcttaccact tgatgaattg 410640
tttatttatg ctgttaatta tttagaaacc cattatgcaa acattgtttg taatcgctac 410700
aatattataa tcgacttaaa taccgattgg gtagaaaaag catatgatga tattgcaaaa 410760
aatcgtaaaa tcaaaccagt gcgtggctat actgactatg atcgggttat ggaagtgttt 410820
tttaatgata tttttgatgg taatatgggg aaaataactt gggagttgcc aaatggaacg 410880
ctatgagtat gaagaaaagt attatcaagc tggatatgac tatatcattg gtttagatga 410940
agctggtcgt ggtccgatgg ctggagaatt ggttgttgct ggagtggttt ttcctaaagg 411000
gttttatgat gaaagaatta atgattcaaa gcagttaagt gctaaaaaac gagaagtatt 411060
gtacgatttg attattgaaa atgcattata ttatgatatt gaaattatta gtgttgcaga 411120
tgtcgatcgt ttgaatgtgt accaagcaag taaacagggg atggaaaaat gtttagaact 411180
actaaaaaaa gagaagatgt ttgcattaac agatgcaatg ccgattgatt atcctgacca 411240
tctttcaatc attaaaggtg atgctaaaag tatctcgatt gctggtgcca gtatattggc 411300
taaagtgacg cgtgatcgtt tgatggaagc ttatgctttg gagtatcctg aatatggttt 411360
tgaaaagcat aaaggatatg ttacgaaagc acataaagaa gctctgggaa aatatggagt 411420
ttgtccaatt catcgtaaat cttttggacc ggtccaaaag atattatcaa aacagatgtc 411480
atttgatttt taatgacatt tttttgattt ttaaaagtaa ttttaagttt aatgaagtat 411540
ataataatga ggtgataaaa atatggaaga aatcttatta tatttttcat taaaatatgc 411600
aggtgatttt gattcgattt taaaagcttt agagtgtaaa gaaaagatag atgaaaaatt 411660
gaaaaaagaa ttgtttaaag atattacagc caattacact actttgatct cgccagatta 411720
tccaactgct ttgaaagaga ttgcctgtcc gccattcgtt ttattttatt atggtaactt 411780
agctttggtt aaaaataaat gtattagtgt aattgggaag cgacatccta gtacatatgg 411840
cgtagaatgc acagcagcac tagcagcaca gttggttgaa gcaggttaca caattataag 411900
cggtatggca atgggaatcg atacgattgc acatcaaagt acaattacag ctaatggtca 411960
aacaatagct gttttaggaa gtggtattga ttattgctat ccacacagaa atcaacagct 412020
gtatcaggtt ttaaaagatc atcatttagt tatcagtgag tatccgggaa aatttatacc 412080
acaaaaaata aattttccaa gaagaaatcg cataatttca ggattgagtg aatctatatt 412140
agtaactgaa gcaaatcagc aaagtggtac gatgatcaca gtcgggcacg gtctagaaca 412200
gggaaaagat atatattgtg ttcctagccg tatcaacgat gctttgggtt gcaattattt 412260
aattcaacag ggtgctaaat tagttataaa tgtgagcgac attcttaatg gataaaaaca 412320
gttttaaaaa atttagttga caaaacttta aaaaacacta ataattgtgt taatcgcgtg 412380
gaggaaatga aatgagcaaa aaattagtta ttgtcgagtc gccatcaaaa tccaaaacaa 412440
ttgaaaaata tttagggagt gattatgtag tcacttcgtc aaaaggacat gttcgggatt 412500
tggcaacttc aggaaaagaa gggttaggtg tcgatattga aaatcaattc gaacctaaat 412560
atgttataaa taaagacaaa aaagatgttg ttaaggaatt aaaacaactt ataaaagaat 412620
cagatgatgt ttatctagca actgaccctg accgcgaagg ggaagcaatt tcatggcatt 412680
tagctcaagt attaaatgtc gatatggata aagaaaatcg tgttgttttc aatgaggtta 412740
caaaggatgc agtagttgat gcactaagtc atcctcgtaa aattgaccaa aatttagtta 412800
agtctcaaga aacaagaagg gttttagatc ggattattgg attcaaactt tcaaaactgc 412860
tacaaaaaaa gatcaaatct aaaagtgcag gtcgtgttca gtctgttgcg ttaagattga 412920
ttgttgaaag agaacgtgag attgaagctt ttgttcccga agaatattgg aaaataaaag 412980
cagaatttga gaaagacaaa attgaattta gtggtgaact agctaaatat aataataaga 413040
agattgagat aaaaaatggt gaagaagcta ctgcaattta tgaagcttta aataaagaat 413100
ttgaaatcgc tagtgtcaaa aaaacgacta aacggcgtga atcaaaacca ccttttatta 413160
cttcgacttt acaacaagaa gcatcttcta aattaggttt taaagcgaga agaacaatgt 413220
caattgctca aaagctttat gaagggatta ctttagaaaa tgagacagtc ggattaatta 413280
cttatatgcg tactgactca actcgtttat cagatacctt tgtcagtgca gctcaagatt 413340
atattggtga aaaatatggt aaagagtata ttggaaaagt aaaagtagga aagaaaaaag 413400
aaaatgttca agacgctcac gaagggattc gccctacgag tgcattaaga acgccggaaa 413460
gtgtaaaaga atatttaaag ccagaagagt taaaattgta ttcattaatt tacgctcgag 413520
caatggcttc attgatggct ccagcaaaat ttgatgcaac ttcagtatca ttgatgaata 413580
atggttatga gtttaagact agtggttcag taatcaaatt tgatgggtac ctaagagttt 413640
acggcgatta tgaaaaacaa agtaatgaaa ttttgccgga gcttaaagaa aaagaaatgt 413700
tattaagtaa aaacattgaa aaaactcaac attttactaa accaccagct cgttatagtg 413760
aagcaaaatt aattaaagag atggaggaac tgggaattgg tcgtcctagt acttatgcaa 413820
tgattattga tacaattcaa actcgtcaat atgttgaatt ggttgataaa gctttcaaac 413880
cgacagaatc tggaatcttg acaagtgatc gattaacaga atattttaat gatattatca 413940
atgttgaata tacagcgaaa atggaacatg agcttgatga tattgctgaa gggcaagatg 414000
aatatgctca cgctttacaa aagttcttag atttatttca accgttgctt gataatgcat 414060
atgataaaat ggaagtgatt gcaccgaaga aaactggaga aaaatgtcct gaatgtggac 414120
atgatctagt tgaacgtaaa ggacgttatg gaacttttgt tgcctgcgaa aattatccag 414180
aatgcaaata tgtaaaaaaa gaccctgtag agattgaata tacgggtgaa gaatgtccta 414240
agtgtggaag taagatgatt tttaaaaatg gtcgttttgg acgttttgaa gcatgttcaa 414300
attatcctga gtgtaagtat attaaaaaca gcaagaaaaa agaacctgtt acgacggatg 414360
aagagtgtcc aaactgcggt tctccgattg taatcaaaca aggacgttgg ggtgagttca 414420
aagcttgttc aaattacccg aaatgtaaga caatcataaa gtagaacgaa agttctactt 414480
ttgttttcaa aatagaaatg ataaaattag aaaaggtgat aaaatggaaa aaattgtaaa 414540
tgtaattgga gcaggtctgg ctggtgtgga agcctgtcat caattagtaa aaagaggata 414600
taaagttcga ctgtatgaaa tgcgtcctaa aaagatgacc ccagctcatc atagcggtaa 414660
ttttgcagaa ctggtttgct ctaattcact tcgtgctgat gggactggaa atgcggtcgg 414720
tgttttaaag gcagagatgg aaatgatgga tagtctcatt attaaatatg ctagaaaaca 414780
tcaagtccca gcgggaggat cacttgcagt tgaccgtaat aatttttctc aagcgataac 414840
ggagtacatt cagagtcatc ccttgattga agtaattcat gaagaggcaa aagaatttcc 414900
tgcaggttac acaattatcg catctggtcc tttgacaagt gatgctcttg caacagcaat 414960
taaagaaaag ttaggggaag attattttta tttttttgat gcagcagcac caatcattgc 415020
aaaagaaagc attgattttg caattgcgta ttataaatct cgctacgata aaggggataa 415080
tgaatatatt aattgtccta tgaatgaagc acaattcaat gctttttatg atgccctagt 415140
caatgcggaa gttgttaaac ctaaagattt tgaagaaaaa ttttttgaag gctgtatgcc 415200
ttttgaagaa atggctcgcc gtggaaaaca aacgttgtta tttggaccga tgaaaccagt 415260
tggacttact gcgccggatg ggacgcgccc ttatgctgtt gtgcagttaa gacaagacaa 415320
tgtccaagca agtttatata acattgttgg ttttcaaaca catctaactt ggcctgaaca 415380
aaaaagaatt attcaaatga ttccaggact tgaaaatgca agttttgttc gatatggagt 415440
aatgcatcga aatagtttta tttgttcacc aaaacatcta ttaaagacat accagttaaa 415500
aaattattct aatatattta tggcaggtca aattactgga gtagaaggat atgtagaatc 415560
tgctcaaagt ggtatggctg ccggaataaa catggtccgg ttattagaag ataaagagcc 415620
tttgattttt ccggagaata ctgttatggg agcgttggct aattatataa ctaatgcctc 415680
gaaagaagat tttcaaccaa tgaaagctaa ttttggaatt ttgccagatt ttccaatacg 415740
aatcaagaaa aaagaacgta aagctgctta tgcatcaaga gcgttggaaa caatgaaggg 415800
atttgttgat gaaaacaacc ttggataaat atttccgaca atatcttgat tatttacaat 415860
atcagcgtca ctatgctgat aaaacaatag aatcgtataa gcgtcagatc gatcatttca 415920
aacaatttct tattgaagaa tctattgatg attataatga tgtgagttat gcaatgctac 415980
gtggatatct tactaagcta tatgaaaaaa atctttctaa aacaacaatt aatcataaac 416040
tcagtgcgtt aagaagtttt tttaactatt tattaaaaga agagttaata aatgataatc 416100
cttttttgct gattgaatcc caaaaagttg caaagcgtaa tccggatttt ctttttcctg 416160
aagaaatcct aggactatta gatagtattg aaacaaaaga tgatctggga attcgtaata 416220
aagcgatgat ggaattaatg tatgcatcag gcttgcggtg ttcagaggtt gtaaatttac 416280
aactttcaaa tatagatttt aatcaaatgg tattatttat tcatggaaaa gggaataaag 416340
atcgttatgt tccatttcat gattatgctg gagaatggtt gattaaatac atacaagaag 416400
ctcgtgaaaa tttaatgata aaaaatgagg ggcataattt cgtctttgtt aataaattcg 416460
gtaatcctct aactaaccga ggagtagaaa acatagtaga tcgaataatg cgactttatg 416520
attcaaccaa aaaaattcat cctcatacaa ttcgacattc ctttgctaca catttattaa 416580
atgcaggagc agatattaga actgttcagg agttgttagg tcatgaaaac ttatcaacca 416640
ctcaaattta tacacatatt tcaagagatc atttaaaaga ggtatattta aaagcacatc 416700
cacgaaatat tgaataattc aagttaaaat gatgaaaaat atgcttgtat gattgaaaaa 416760
tctatgataa aatgtttcag gtatgaaaaa tacacacatt atgaattcat ttatctagtg 416820
ccgtaaggtg ataaatgttc gaaataatgg aggaaaaaaa caaaaggagg aagttacaat 416880
gtcagtaatt tcaatgaaaa aattattaga agtaggtgtt cattttggac atcaaacaaa 416940
aagatggaat ccaaaaatgg ctccatacat tttcacatca agaaacggga tttatattat 417000
tgatttgcaa aaatcatcta aaaaaatcga tgatgcttat aaagcaatga atgaaatcgc 417060
tgctaaaggt ggaaaagtat tatttgttgg tactaaaaaa caagctcaag aagctgttaa 417120
agaagaagct attcgttcag aaagtttcta tgttaactct cgttggttag gaggaacttt 417180
aacaaacttc aaaacaattc aaaaaagaat tagaagatta attgaattag aaaaaatgga 417240
agctgatggt acttttgatt tattgcctaa aaaagaagta atcttactta aaaaagaagc 417300
tgctaagtta gaaaagaact taggtggtat caaagaaatg agaagattac caaatgcttt 417360
attcgtagta gatcctaaag ctgaacataa tgctgtagca gaagctaaaa tcttaggtat 417420
ccctgtattc ggtatcgttg atactaactg tgatcctgat gaagttgatt atgtaatccc 417480
agctaatgat gatgcaatta gagcagtaaa attaattgtt gctgcaatgg ctgatgcaat 417540
ttgtgaagct aaaaatgaac cattaactgt agcatatgtt aaagatgaag atgataaaga 417600
agtatctatg aacgatgcaa tcacttcagt tgaaaataat caaagaagag cacctagaaa 417660
taaaggtgga agacctaatc ctagaagaaa taatgctcct agaccaaata aagataacac 417720
agctggaact gaaggaaaat aattctgtaa aataagggaa agcaaagctt ttcccttttt 417780
aataaaaaaa acaaataaag gagaaaatta aaatggcaat tactgcaagt ttagtaaaag 417840
aattacgtga aaaaactggt gctggaatga tggattgtaa aaaagctttg gaagcttgtg 417900
atggtgacat cgaaaaatca tttgactggt taagagaaaa aggaatcgca aaagctgcta 417960
aaaaagctga tcgtatcgct gctgaaggtt taactgcttt cgtattagat ggggatactg 418020
ctgcaattgt tgaagttaac tcagaaactg acttcgttgc taagaacgct gaattccaag 418080
ggttagttaa aaatatcgct gaagttgttg ctgctaataa acctgttgat ttagaagctg 418140
cattaaacac tgaagtagat ggtaaaaaat tagaaactgt tatcgctgaa gctagcggta 418200
aaattggaga aaaattaagt ttcagaagat tcgaagtttt aactaaaact gctgacgaag 418260
tatttggtgc ttattctcat atgggtggaa aaatgactgc aattgttaaa gttgctaatt 418320
ctactgaaga taaggctcgt gacgtggcta tgcatgttgc tgcttctgat cctaaatata 418380
ttgatagaac tgcaattcct gctgaagttt tagatcatga attatctgta ttaaaagctc 418440
aagcaatgga agaaaacgca gcagctgcta aacctaaacc agaaaatatt attgaaaaaa 418500
tggttgaagg tagattaaat aaaaacttaa aagaaatgtg cttagttgat caagaattca 418560
ttaaaaatcc ggatgaaact gtagctaaat tcttaggtga aggtaaagta atcaatatgg 418620
ttagattcca agttggtgaa ggtatcgaaa agaaagaaga aaactttgct gaagaagttg 418680
ctgctcaaat gaacgcaaaa taataacttt taaaacacta tcattagata gtgttttttc 418740
tttggataag cgtcattcga ctaggaatgt accttgacta aacgacgaaa atatgataaa 418800
ttttttagag gaaaaagtaa tcattattag ctgataatga tgtgcgaatt taagcataaa 418860
tcttttttta taaaatataa ataaggagat taatatgaag tataatcggg tattattgaa 418920
attaagtggt gaagcattgg ctggagatga taaaactggt atcaacgctc atacagtagc 418980
agatatcgct cgtcaaatta aagatgccaa agatttagga gttgagattg caattgtttg 419040
tggcggcggg aacctatggc gtggtaaaac tggtgctgat atgggaatgg atcgttcaag 419100
tgctgactat atgggaatgc tggctactgt aatgaatggt ttagctgttc aaaatgcatt 419160
ggaggccatt ggcgttccaa ctcgtgttct ttcagcgatt gaaatgcgtc aagttgctga 419220
accatatatt agaagacgag caattcgtca cttagaaaag gggcgagtag taatatttgg 419280
agctggaaca ggaagtcctt tttttacaac agatacaaca gctgctttga gagctgcaga 419340
aattaacgca gatgttatcc taatggctaa aaacggggta gacggagttt attcagctga 419400
tccaaaagtt gatcctaatg caattcgctt cgatactatt tcgtattttg atgtattaca 419460
aaaagattta aaaatcatgg atcaaacagc tatcacttta tgtaaagaca ataatattga 419520
tttatgtgta tttaatatgt ctgtagacgg aaacattgct aaagcatgta atggcgatga 419580
tatcggaaca acaatctcag gaggaaaata aaatgataaa tatgatttta gatgatacaa 419640
atgaaagaat gacaaagacg attgaatctt tccaacgtga tttatcatct gttagaactg 419700
gtcgtgcaaa tcctaatatg cttgatcgag taatggttaa ctattatggt tcaccaactc 419760
cagtgaatca aattgctggt atttcggtag tagaaggccg tcaattagtt attaaacctt 419820
atgacaaatc aagtattaaa gatattgaac atggcattta tgaagcggat ttaggtctta 419880
ctccacaaaa cgatggtgag attattcgta ttatggttcc cgctttaact gaagaacgtc 419940
gtaaagagtt tgctaaaaat gtttggaaat ttgcggagaa tgctaaggtg tcaattcgca 420000
atattcgccg tgacagtaat gatgaaatta agaaaacaga tggtagtgaa gacgaaatca 420060
aagctggtca agaaagagtt caaaaattaa cagataaatt tgttaaagaa attgatgaaa 420120
ttgcaaaagt aaaagaaaaa gatatcatga ctgtataatt agatgggcgt tttaaacgcc 420180
cattttatct aatttattta gaaagaagaa aatatatgca taaaagacca tgttcggatt 420240
gaaatttaga tagcgaaata tttcgtagct actattattt aaaagaagag cctgtggcat 420300
tttgtcgagt taatggatta cctatgagtg gtggtaaagt ggaaattaca gagagaattg 420360
gttatttttt agatactggt aatatttcgg atttgataag ttcgaataaa agtaaatgtc 420420
aaataggaat tataacagaa gatagtaaaa ttgaagaaaa ttttgtttgt tcacaaaaac 420480
atcgtgtttt ctttaaagaa aaaatagaca aaactttttc ttttaacgtc ccatttcaaa 420540
aatggttgaa gacgaacact ggtaaaatat atctgatgca attaaagcat attatgagat 420600
tttagaagca aaaaagtcaa caaaaactgt aattgataaa aaatttgaat ataatacata 420660
tattctgatt tctttaaaaa taacaaagga aagacattag aacaggcaat cagatgctgg 420720
aattataaaa agctgtaaag accataatcg ttatgaaggt gtatattttc ttattttaat 420780
gtagtaaatt aaataaataa tttatatgta ctaggatgat taagtctagc aatgttgctt 420840
aggctttttt tgtaatgaat ttatggtata atctcgaata gttaaacagg aggacgacaa 420900
atgtttttta agaaaaagaa gaatgaagaa tttaattatc atgttcttga taaagataat 420960
attcctcaac atatagcttt tattatggat ggaaatggtc gttgggcaaa aaaaggaaga 421020
tgccacgcac ttatggacat catgagggga ctaaaacaat tcgagatgtt gctttgcatt 421080
gtaataagtt aggagtcaaa gctatgactg tatatgcttt ttcaaccgaa aattttgcac 421140
gaccagagca agaggtacag tatattttta aattaccaaa agatttcttt gaattgtata 421200
tgaaagaact gatagaaaat aatgtaaaaa tctgtacaat cggacattta gaaatggctc 421260
ctaaagaaac tcaagatatt attaactctg caattgataa gactaaaaat aatactggtc 421320
taaaattatg ctttgctttt atttatggtg gacgtgatga aattttagaa gcaacaaaaa 421380
aactagcaat gaaagtaaaa gctggtgaat taggtgtaaa tgaaattaat gaaactgtct 421440
ttaatgatga gttgatgact aaggatctac cggaagttga tttaatgatt agaactagcg 421500
gggaacaacg tttgtcgaat ttcctgttat ggcaattagc atatgcagaa tttattttta 421560
cagatgtttt atggcccgat tttaatgaaa atgaacttga taaagcgatt tggatgtacc 421620
aaaatcgtga tcgtcgtttt ggaggattaa aataatgaaa gaaagaatta ttacggcaat 421680
ctgtttgatg ctggttgctg ttccttgtgt tatatttggg ggatattatt ttaaaggctt 421740
gattggagtg attctagcat tggcagtgta tgagatgtta catatatgca ctcgtccaaa 421800
aataaaaatg tatttatatc caatcgtctg tggatttttt atctatggtt ttttatttga 421860
ccaggatgat ttatttttag cttcttatgg aatcttaatc tatttgattg tcttatttgg 421920
agcaacaatt tttgatgaca ccttgacaat tgaacgcact agttatattt ttacgatggg 421980
ggtactaata tgtgctggtt tacacgcttt aatgtcactt cgtgatgtat atggttttca 422040
atatatttta ttgcttgcgt tagctactta cggtagtgat acaggcgcat attttgcagg 422100
agtttttttt ggtaaacaca agttgattcc tcgattatct ccaaagaaaa caatagaagg 422160
atcaatcggt ggggtgctgc ttgggacttt actatcagtt gggtatgcta gttatttagg 422220
tttgttagaa aataatgtga ttttaattgc agcatttttc gttttaactt tcactagtca 422280
aattggtgat ctagttttta gtgctgtgaa acgtcatttt ggagtaaaag attactctaa 422340
tttattacct ggacatggtg gcatattaga tcgtattgat agtattttat ttaatgcaat 422400
agtttttagt ttctttttag taatggtgag gttataaaat gaaaaaaatt acagtattag 422460
gagttactgg atcaattgga atgcagacag ttgatgttgt aatgaatcat cctgaacagt 422520
ttaagattac agcaatggca gcagggtata atgtggctaa ggttgaggaa attttagcaa 422580
tgattgatgt tgagtatatc tgtatggtaa aaaaagaaga tgctttatat cttcaagaaa 422640
aatatcctga tcttaaagtt gtttatggtg aaagtggatt gatagaaatt gcaactttac 422700
cagagattga gattgtatta aatgcaattg tcggatttgc tggtttagtc ccaacaattg 422760
aagcaattaa agcaaaaaaa gatatagctt tggcgaataa ggaaacttta gtcgtagcgg 422820
ggcatataat tactgaactg gtaaaagaat atggcgtcaa acttctaccg gttgatagtg 422880
aacactctgc tatttttcaa tcattaaatg gcgaagaaca caataaaatt aagaagatta 422940
ttttaactgc tagtggtggc agctttcgtg ataagcaacg tgatgaatta gcaggtgtaa 423000
ctgttaaaga agcattaaac cacccgaatt ggtcaatggg agctaaaatt acaattgatt 423060
ctgcaacttt atttaacaaa gggttggaag taatggaagc aaaatggtta tttgacgtgg 423120
attatgatca aattgaagtt ttaattcatc ctgaaagcat cattcattcg atggttgaat 423180
ttgtggatac ttcaattatc ggacaattag gcaatccaga tatgcggtta ccaattcaat 423240
atgctttaac ttatccagaa cgtgattatt taattggtgg tgaaagtctt gatttagcaa 423300
agattgcatc attaacattt aaaaagccag attttgaacg ttttagagca ttagctttag 423360
cttatcaagc cggcaaaagt ggtggaagta tgccgtgtgt gttaaatggt gcaaatgaac 423420
aagcaaatga gctatttaga aatggtaaaa ttgagtttct tgaaattgaa aatttagttg 423480
agaaagcatt gaataaacat cagttagtca aaaatccaac acttgaacag ttgattgaaa 423540
tcgatgcttg ggctcgaaac tttgttttaa aagagatagg agaagattaa tgcagacatt 423600
aattaatatt gtcgttttta ttttgattct tggaatcgtt gtgctgatcc atgagttagg 423660
acattttatt acggctaaat cgtttggggt ttattgtagt gaattttcaa ttgggatggg 423720
accaaagata ttttcgcgca aaaaaggtga gacagaatat gaaatcagag ctttaccaat 423780
tggtggtttt gtatcaatgg ctggagaggc tgataatgat attgaggaat ttaaagatgt 423840
tccaattgag cgtactttaa agggcattag ctgctggaaa aagtgtgttg tttttttagc 423900
cggagtcttt atgaattttg ttctatcatt agtaatttta attggtgttt attgtgtaat 423960
agatgttcaa actaatacac ctgaaatcgg gaaagttact tcggacagtc ccgcaatgat 424020
tgcaggcctt gaggcgggag atactatttc taaaattact tatgatggtc atgaaaatat 424080
tattgcatct tttgcagaca ttcgtgaagt gttgaataat gataatctta aatcaaaaag 424140
tgctacaata atgttgcaag ttgaattggt ccgtgatggt aaaacaatta ctaaagaagt 424200
taatgcaaaa tataatagtg attctaattc atacacaatg ggtttgactc cagcaacaag 424260
aaatttaagc ttttttgaag ctattaatta tggggtaact aaatttgtag agatggcgct 424320
gttgattttt acaacattag gtaagctatt tacagactcc gctaatacaa ttggacaatt 424380
gtcaggacca gcgggaattt acaacgtaac ggctcaaatt actgaaacag gatcaattag 424440
tcaattatta acattgctag ctttattatc gactaatatt ggaatgttca atttattgcc 424500
tattcctggt ttagacggtt gtcaagttat ctttgctgtg gttgaaagag taatcgggcg 424560
tgaattaccg ttaaaggtta aatatggttt acaaattgct ggattagccc ttgtttttgg 424620
tctaatgatc tttgtaacct ttaatgatat ttctagaata tttggataaa gggaattaat 424680
tttccctttt ttatgctata atgtttgagt gttatattga taagaataat gaaggatgat 424740
ttgatggaaa ataaattatt aatattatta aaaaatttaa agattgaaag ccaagctaat 424800
attttaaaag aaggaaaaat cagtaaagtt gttgtagcga gagataatag ttatactttt 424860
cacttagtgt ttaatcagat tttgccattt gaggagtatc aattattaat aaataaccgc 424920
gataattttc cttatcctac taaatataaa attagttatg aaactgaatt ttttaatcaa 424980
aatgaattat tattatatac cggatacctt ttagaaaaat taaaaaaaga ttatcctgtt 425040
tgtgctactt taacagttga aagttttaaa atcgaagata aagttattag agtagaaaca 425100
tgtaatgaaa ttcagttaga acaattacgt cagttaagag cacaaattga agatatgttc 425160
aatgatgtag gtatcgataa aaattttgat ttttatattg atgaagaaaa cgatgtattt 425220
aaagatatta aagaagagat ggaagcttat gaaccagttg aaattgacct ttctttaatc 425280
caaaagccag ataaaccggc gtcagaacaa aataattata agaataatta tcgtcaaaaa 425340
aatgcagcaa tcgatatgaa aattgaagag attactaatc agacaatgga taataatatt 425400
gtaataaaag gctttgtttt taaaacagaa atgattaaaa caagagcggg aaaacatatt 425460
caaagtttat gggttacaga ttatactgat tcaattattg ttaaacgttt tgaaaacaat 425520
tctaataact cgttagaaga attaaaagtt atcggtaaag gcggagtttg ggtaaaagtt 425580
cgaggtgaag cccgttttga tagctttgca cgcgaaacag ttatgatggc tcgcgaggtt 425640
gaagtgatta agagcccagc accacgtaaa gatactagtg aagcaaaaag agtggaatta 425700
catacacatt caaaaatgtc agcgatggat ggggttggaa caattaccca atatattaac 425760
gctgtagcaa gctggggaca taaagcaatt gctgtaactg atcatggtaa tgtccaatct 425820
tttcctgaag ctcaaatggc agctggaaaa gcaggaatta aaatgatcta tggtgttgaa 425880
ttcaatatga tcgaaccgat tttgaatatt gtttataacg aaatagatac ctcaattgaa 425940
catgcaacct atgtttcttt tgacttggaa acaacaggtc tatcagttat tcacgatggg 426000
attacagaat ttggagctgt caaaattaaa aatggagaag taattgatcg actgcaaatg 426060
tttgtgaatc cagggaagag catttcctca agaatcacta atttaactag cattactaat 426120
gatatggtac gtaatgaacc gacgattgat gcattattgc ctagaattat agaatttttt 426180
gatgattgta ttttagtcgc tcataatgct aattttgata ttggattttt aaatgagaat 426240
ttacggcgaa ataatatgcc tgaaattacg aacccaatta tcgattcatt ggctttagca 426300
cgagcaattt tgaaaccgat gaaatcgtat cgattgggga atgtgtgccg cagttatcga 426360
gtaaattatg atgatgaagt ggctcaccgt gctgattatg atgctgaagt attaggtgat 426420
gtttttaaca tgatgttaca tcaaattatg caaagcggta aatataatct tttagacttg 426480
tgtgaattaa caggggatga tgtttataaa attgtttatc cttatcatat gaccgcattg 426540
gcgttaaata aagctggttt aaaaaatatg tttaaattgg ttagtgaagc aaatactaaa 426600
tattttcata atggatcaag aattcctaaa gaacgtttag aacattatcg agaaggctta 426660
ttatatggca gcagttgcta taacggtgat gtttttgagg cggctctgaa cttatctgat 426720
gaaaaattag aacgggccat ggaattttat gactatattg aaattcaacc acttgaggac 426780
tactatcact tagttgatcg tggaaaattg caagatactg atgagttaat caaatcttta 426840
catcggatta ttgattgtgc aaaaaaacta gataaattaa ttgtagcaac tggtgatgtt 426900
cactttttag aagttcgtga taaaattttt agagatgttt ttatctctaa tccgacgatt 426960
ggaattggtc accgtgctca tccgctgtgt gatcgacgca atcctaaggc taaaaatccc 427020
tgccaatatt tgagaacaac taatgaaatg ttagaaggtt atccttattt accacaagac 427080
gaagtatttg aatatgttgt tacaaataca aataaaattg ctgatatggt tgaggaaatc 427140
aaaccagtgc atgataaatt gttcacgcct aagatagatg gtgcagacga aaatctaaag 427200
aagatttgtt acgatactgc gcataagaca tatggtaatc cgttaccgca aattgttgaa 427260
aagcgccttg aaaaagaact tagtaatatc atcaagcatg gctttggggt catttactat 427320
atttctcatc tattagtaaa aaaatcaaat gatgatggct atctagtagg ttctcgggga 427380
tctgttggtt cttcatttgt tgcaacaatg tcaggaataa cagaggtaaa tccgttaccg 427440
ccccactatg tatgcctcca ttgttcgcat agcgaatttt tagaagaagg aattgtggct 427500
gatggctatg atttggaaga taaagtgtgc cctaaatgcg gtaaaataat gaagggtgaa 427560
ggacataata ttccatttga gaccttcctt ggatttaacg ctgataaagt accggacatt 427620
gatttaaatt tctcaggtga atatcaagct aatgcacatg cttttactaa agaaatattt 427680
ggtgaagatc atgtttttag agcaggaacg atttcgacag tagcagaaaa aacagcttat 427740
ggatatgcaa aaggatatgc tgaattaatg gggactgatc aaacaattcg ttctgctgaa 427800
ttagagcgaa tcgcagccgg ctgtggtggt gttaaaagaa caacaggaca gcatcctggt 427860
gggatcatcg ttattccagg ggatatggat gtatttgatt ttacaccgta tcaatttccg 427920
gcagatgatc taaatgctgc gtggaaaaca actcacttcg atttccatgc tattcatgat 427980
aatgttttga aatttgatat tttaggccat gtcgatccga ctgtaacacg atttttgcaa 428040
gatctgacag gtgttgatcc taaggatatt ccaactaacg ataaaaaagt tatgagtttg 428100
tttactagca gtgaggcatt aggatgtaat cttgatttta ttggttgcaa aaatggagct 428160
ttagggcttc ctgaatttgg tacctcattt gtacgtggaa tgttagatca aacccaacct 428220
aaaacattta atgatttagt tattatctcg gggctatcac atggaactga tgtatattta 428280
ggaaatgctg aaacgttaat taaatctggg acttgtacac tttctgaagt aattggatgt 428340
cgtgatgata ttatggttta tttgattgaa aaaggtttgc caaacaagga tgctttcgat 428400
atcatggaat gtgtccgtaa aggtaagtca ccggtagttt ttccagaaaa aaaatatgaa 428460
gaactaatga aagaatacaa tgtaccgcag tggtatattg attcttgtaa aaaaattaaa 428520
tacatgttcc ctaaggctca tgctgctgcc tatgtattat ctgcaattcg agtagcttgg 428580
tggaaattat attatccacg agaatattat gctgtttatt ttacaacgag atgtgatttt 428640
tatgatattg aaacacttgt acaaggtaaa gatgctatca tggcaagacg agctgaaata 428700
acgcagttaa gagctgaacg gagttcttca aacaaagatg aaggattatg ggatattttt 428760
gaaatcgcac tagaaatgat tgagcgggga ttccatttta atccagttag tttagagtat 428820
tcacaagcta gcaagtttat attagatcca aacgatgaaa aagggttgat tccaccgttt 428880
agtgcaattg atgcattagg tgaatcagta gctaaaacag ttgtagatgc tcgagcagat 428940
ggtccgtttt tatctaaaga agatgttatt aaacgaacaa agttgaacaa ttcacatatt 429000
aaaacactat ctaaaatggg ggtttttaat ggaatgcagg agcgtaatca actttcactt 429060
ttctaagtag ttgcaataat taaaaaaatg tggtattatt tatttagttt catagagaag 429120
cgagtggggt gacccactct ttattattga atagaggtga aagaatggaa cttttagata 429180
cgattaaaac actgataaaa ccaattttag aaaataatga tgtatatctt gatgatattg 429240
aataccttca ggaaaatggc gaatggtatc ttcgcatttt tgttgaaaaa aatgaaggtt 429300
ccctagacat ggacacatgt gtagcagtta gtgaagcaat tagtttaaag atggatgaag 429360
aagatccgat caaaggagaa tattatttag aagtttcttc accaggtgta gaaaagcccc 429420
taaagacttt tgagcaagtt aaagcttcag taggtaagta tgtctacgct aaattcatta 429480
atccaactgc tggaatggat gaagtggaag gatttattaa aacaattgaa gatgaaacga 429540
ttgaatttga atatttagtt aagaatatta agaaaagaat taaaattgac tatagcaata 429600
ttaaatttat aagactagct gtgaaatttt aggaggataa aaaagtggca agtaaaaaat 429660
tcatggatgc actaaattta ttaattgaag aaaaagggat tgaaaaagat gtctttttag 429720
aaatgcttaa agaatctatt ggtaaagcat ataagaaaaa ttatttaaac cctgatgcta 429780
atgtccgtgt tgaaattaat gaaaaaactg gaaagtttag attatttgaa cttcgaacag 429840
ttgttgatga tctagatgat gaagatattg aattatctct agaagaagct caagcaatca 429900
atcctaatta tcaaattgga gatgttgttg aaactgaagc cgatatcgaa catattggac 429960
gtttggcagc tattcaaaca aaacaattat ttagacaaaa gattcgcgaa actgaaaaag 430020
aaacacttta taacgaattt gcagataaaa aagatgatat catcacaggt atcgttgatc 430080
gtgttgagga taaatttgca attgtaaata ttggtaaaac aggagctttc ttagcttcta 430140
atcaacaaat tcctggtgaa aaattaaatg agggtcaaca tttaaaagtg tatgttagcg 430200
atgttgatcg tggaactaaa ggaactcata ttgttgttag ccggacagag ccgagttttg 430260
ttaagagatt atttgaatta gaagtacctg aagtatacga tggaacagtt gaaatcaaag 430320
cagtttcacg ggaaccaggt gaaagaagta aggttgctgt ttatactagt aatgaaaata 430380
ttgatccaat tggctcttgt gttggaccaa agggaagtcg agttaaaaat gtagttgatg 430440
agttaaatgg tgagatgatt gatattattt tatggagtag tgatccggtt gtctttattt 430500
ctaatgcctt gagtccatct gatgttaagt gggtatctat taatgaagaa aatcacagtg 430560
ctttagtagt tgtaccagat gatcaattat ctttagctat cggtaagcgt ggtcaaaacg 430620
ctcgtttagc agtacgttta acaggttgga agattgatat taaatctgtt agtgaggctg 430680
ttgaacttgg tttaattgat cttcaaacag ttaataatac agaagaatca tcacctgttg 430740
atgctagttt tgaagaagag tttgctcaag aaatgttaga tgaagcagtt gaggaagctg 430800
ttgtggaaga agctgttgaa gttgcagaag aaccagaaat cgaagaagaa gttgttgagg 430860
ttgaagaaga acctactcaa tcgaaaaagg ttattgaata cgaagatttt gaagatttag 430920
atgatgaata tagtaaatat gatgaagaaa tcgattacga tgaatatgat gaatactatg 430980
ataaagatta aggagtgatt aaattgcgaa aaatcccttt aagaaaatgt ttagcaacgg 431040
gtgaacagtt gccaaaacaa caattaatca gaatcgtacg taataaagaa ggtcaagtag 431100
ctgtcgatcc aactggtaag atgaatggac gaggagctta tctgaaacgt agtcatgaag 431160
cgttcgtgtt agcaaaaaag aaaaaagttt tagctcgggc tttgcaggtt gaaattcctg 431220
aagaaatttt cgtagaactg gaaaaatttg cggatgaata attatttaaa tacacttggc 431280
ttggctgcgc gagctcgaaa aatcattact ggtgaaactt taatcacaaa gattagaaat 431340
aacgaagtag aatttgttat tattgctagc gacgctagtg acaatactaa aaaaaagatc 431400
accgataaat gtacaagtta taaagttgag tatgttatag cttgtactat tgatgaacta 431460
tccagtgcaa tcggtaaaaa aaatcgagta gcacttggta tccaggatac tggatttgct 431520
aaaatattaa aagaaaagat aggagggtga acatatggca aaacaaaata aacaaacaaa 431580
aaataaaaaa ggtgcgccaa gaaagaaaca attaaagtct aattttccga ccaaaaaaga 431640
agaaatagtt gctaaagatg gtgtcattgt ttatgaagaa ggtattactg ttggtcaatt 431700
agctgataaa attggacaaa cgcctgccaa tgttattaaa gtattgtttc tattaggaac 431760
gatggtaact attaattcat ctttaaatga tgagcaagta gaattaattt gtcttgaata 431820
tggttttgaa gtcgaaaaac atgttgaagt tagtgaagtg aattttgagg aaattgatat 431880
tcaggatgat gagaaggatt tacagcctcg ttgtccagta gttacaatta tgggacatgt 431940
tgatcatggt aaaactacat tgttagatac aatcagaaag tctgcggttg tagaaggtga 432000
atttggtggg attacacaac atatcggtgc ttatcaagtt gaagttaatg gaaaaaaagt 432060
tactttctta gatacaccgg gccatgaagc atttactgct atgcgtgctc gtggagctca 432120
agtaactgat attgttatta ttgtagtagc agctgatgat ggtgttatgc cacaaacaaa 432180
agaggcaatt gatcatgcaa aagcagcagg tgtaccaatt gtcgttgcga ttaataaaat 432240
tgataaagaa ggtgccgatc ctgaaagaat caaaggagaa atggctgagc atggtctgct 432300
tcctgaaggt tggggtggag atacagtata ctgtgaaatt tctgctaaaa aaagaattgg 432360
aattgaagaa ttgctagaaa ctttaactgt tgttgcagaa ttagcagatt taaaagcaaa 432420
tcctaatcgt tatgcatatg gcagtgtagt tgaaggtaaa ctagataagg ggcgtggacc 432480
agttgcaacg ttacttgttg aaaatggtac tttaagagcg ggagatccaa ttgtagttgg 432540
aacatcattt ggacgtgttc gtcaaatgct tgatgatcgt ggaaaaatta ttaaagaagc 432600
acttcccgct actccagttg aaattacggg tttaaatgac gttccagttg ctggtgataa 432660
gtttatggct tttgaaaacg aaaaacaagc tcgtagtgtt ggtgaaacac gattaaaagc 432720
gaaacaagat aaagagcgta gttcaggagc tgccttatca ttagatgatt tatactctca 432780
aatcaaagag ggcgaaatga ttgacttaaa cattattgtt aaagctgatg tccaaggtac 432840
tgctgaagca gttaaagctt cattagaaaa aattgatgtt gatggtgtaa gagtaaatgt 432900
tattcgttct acagctggag gaatttcaga atctgatgtt ctattagcat ctgcttcaca 432960
agcaattatt tatggtttta atgttcgtcc aaatgcaaaa gtacgtcaaa aggctgaaga 433020
agaaggaatt gagattcgtt tacacaatat catctataaa atggttgaag agattgaaac 433080
cgcgatgaaa ggtatgcttg ctccagaaat taaagaggtt gttacaggtc aagcagaaat 433140
tcgtcaggta attaaagttt ctaaagttgg aaatattgct ggatgttatg taacagatgg 433200
ttttattcgc cgtaattgtg gaatccgttt acttcgtgat agtgttgttg tatatgaagg 433260
aaaattaggt tcattaaaac gtttccagga tgatgctaaa gaagttgcag cgggatttga 433320
atgtggttta agtattgaaa acttcaatga tattaaagaa ggcgatattg tcgaaggata 433380
tatcatggaa gaagtcgaag ttaagtaggt gaattaaatg attcttaaaa aggataagat 433440
gaatggtatt attcaacgcg agttatcaca aatcattcaa gttgaagtac gtgatcctaa 433500
gataggtttt tgtactatta ctgcagttga tacgactact gatctatcaa ttgctaaagt 433560
atatgtgact ttcttaggaa aagactttga tacgcgcaaa ggaatggaag cattaaatcg 433620
ttctaaagga tttattcgtt ctttattagc taaacgtctt acaattcgta aagtaccaga 433680
actgattttt gttaacgata cctctttaga gtatggtaat aaaatcgaaa aaattattga 433740
tgatttaaat catcatgata aataattcaa aagaaggtca aattgaagtg aagccaattt 433800
cttggacact aatttagtta tgctattaat aaggattgat cctgtattgc acaggagttg 433860
atccttttaa ttttgttgtt atttttttga gtatagtatt gttttataca ttcttctatt 433920
gcaatcttta aattatataa cgatctaaaa gtatattcat aaccataaaa aatttcattt 433980
ttccaacgga attcttcatt ggtgaattat ctaaacaatt tcttttttaa tattgactgt 434040
ggaatttatt cttttcaaaa attttttata cacaatattt ttttgttatc ttgtgagttt 434100
aaccataata aaatgaactc caccatttga aatacctaaa taatgggact acaataaatc 434160
accttctttt tatttgagtc ttatttgttt catctagata gaattgtgct ataatactat 434220
atagatatag gaggactaaa agaaatgaaa tactgtataa caaacgggaa agttatttta 434280
aaaaatcaag tagtagatgc aaatgtatat gtagaaaata caaagattac tgagatttct 434340
aatcgtcaac ctgatgatga aacagtaatt gatgcaaaag gtagatatgt gtcaccagga 434400
tttattgatg ttcatactca tgggcgtggt ggcagtgata caatgtataa cacttttgaa 434460
gatcttgata caattacaag tactgccgta aaaacaggtg taacaggaat tttacctaca 434520
acgatgacga tgtctaaaga agatacttat gcggctatta aaaatgttgg agataacatg 434580
gataaagttg gaggaagtaa aatcctagga gtacacatgg aaggtccatt ttttaataca 434640
aaatataaag gagctcaacc tgaagagttt atgatcaaac ctacagctga aaattatagc 434700
agtttagttg gtgaatatgg taaaattgta aaaaaattaa gtttagcacc agaattaaag 434760
gattctgata agttaatcga gtatttagtc aaagaaggtg tggttgtaag tattgggcac 434820
actaatgcaa cttatgacga agcagttgtt ggaattaaag ctggagcaac ttcaggtact 434880
catacttata atgcaatgac accattaaca catcgaaatc caggagtagt aggagctatc 434940
atggaacatg atgaagttta tgcggaattg attttagatg gaattcatgt cagctatcca 435000
gctgcaaaag tgcttttaag ggctaaaggt ttagataaag tgattttaat cactgattct 435060
attgaagctt ctggtttaga agatggtcaa tataaattag gtaatcaggc tgtatttgtt 435120
aaagataatt cagctcgttt agaagatggg actttagctg gtagtatttt agcaatgaat 435180
aatgcagtaa agaatgcata tcaacattta ggtttatcaa ttaatgaagc tgttaattta 435240
gctagttata atcctgctaa aaatttgaat ttaattgatt taggggaaat tgcagttaac 435300
aaaacagcgg acattattat gtttgatgaa gaaattaatg ttgattttgt aatgattgat 435360
ggaaatgtaa aaattggagg atagtatgat tacattaaag aatgaagttt tagaggttac 435420
tctagctaat aaaggtgcag aaattattaa aattgttggg caggatgatc aaattaatta 435480
tatgtggcgt cgtgatccaa ttcaatgggc gaatagtgct ccaatcctat ttcctattgt 435540
aggtgcgcta caaaataatg agtgtcgaat tgatggtaaa acttatacta tgactcaaca 435600
tggtttttca cgtcatagtg aatatgaggc taatcaaatt aatgatcaag aagtagtttt 435660
tacacttatt tcaaatgagg aaatagctaa acaatatcca tatttattta agttagatgt 435720
aacttataaa ttggataaga atgtacttag ctgtaattgt aaagttacta ataccgatag 435780
tcagactatt tatttccaaa ttggtggtca tcctgcattt gcttgtcctt ttatggaaaa 435840
tgaatcaagt aatgattact atttagaatt tagtgagaat gagactgtta atcaaaaaat 435900
tattgatgtt gaacataaag gaatgtcaga tataacatta ccgtttttag ataacgaaaa 435960
gagatttttt gttcgtcagc aattatttga taatgatgca attgttttaa aggacgtgaa 436020
atcaaaaaca ttatcattga agtcattaaa tcacaataaa tctttagtat tccatatgga 436080
aggttttaat cacttaggta tttgggcagc taaacatgtg ggtggactaa ttgccattga 436140
accttgggta ggtcatagtg attatgttgg tttcactggg gaatttaagg ataaagaggg 436200
tgtagttagt ctaaatccta gtgagatttt tgaatgtact tttaaagttg aaatcaacca 436260
ataatgacaa aaaaggaata agataaattt tataattatc ttatgaaagt aaaaattatt 436320
gaaaaaacac acgagttaga tttagaagat gaaattaatg attttttgga aaagaaaaat 436380
cctaaaattt tatcgctgca ttatcaagtg gcaatgactt tttcaagtga attagaatat 436440
agttttagct gtttgattga gtacgaggat aaataatcat atttatcctt ttcttttcgc 436500
atacttttag tattttagtt aaaactattt atggaggtga ttccatggct aaaggtgtat 436560
gttgtcacgt tgatacttgt gtttacaatc atgattgtaa ttgtgaggca aaagaaatta 436620
cagtttgtaa ttgtaaatgt cacgaagcga aagatattca agaaacagct tgtgaaactt 436680
ttaaatgtaa atagaaagtt taatatgaca tcacaaaagg taagaagtaa cttttgtgat 436740
gtcttttgtt ataagtatga gctttacaaa aagacattta tatgttttat tttttgtata 436800
catataaaaa cgtgatataa taaaaaaggt gataaaaatg aaaaaaattg ctttgattct 436860
aatttgttgc ctagttttaa tagggtgcaa aaataaagac aataacgata ataaatttta 436920
tcgacaatat aaagaatatg aaaataaaat agataatcat aatgaatttt tgaatgctac 436980
aaatgaattt aatatacgtt tagtagtcaa taaagttgaa gataaaaaat atcggtatga 437040
tgttattatt gacacaccga caataaatat gtatcattta caagcaatag caaaagttgc 437100
tggtgatgat aatgaaagtc taccaacctt aggaattctt gaggaagata ttttttcatt 437160
agttcctgaa gtagtagata aagccaatgg aatttataag ggtgtaaatc tatctggtat 437220
tactagtaaa agtgaattta gtgtattggt ttatttgact ttttcaacag ataaacaatc 437280
taataacaaa gaagaaaggt atattaaact atatggtaat gcgacttgat aaattgcttg 437340
caaactatgg gattggtact agaaaagaag taaaatcact gattcgaaaa ggttttgtaa 437400
aagtaaatgg aatgattata aagaaagatg attttaaagt tgatcatgaa attgatgaaa 437460
tagtatttga tgatgagttg attgaatacc ggccatatgt ctatataatg ctgaataagc 437520
cagcgggata tattagtgca actaaagaca atcttcatcc tacagtatta gaactgattg 437580
agggctatga aaattatgat ttatttcctg tcggccgctt ggatttagat acagaaggac 437640
tattgttaat tactaatgat ggtgatttta gtcataaatt attagcccct agtcgaaatc 437700
attcaaaaat atattttgca aatattgcgg gagttatgga tgaacaagat attcaggcat 437760
ttaaagatgg gattatttta aatactggct atcactgtaa acctgccaac ctagaaatta 437820
ttaataaaaa caatgatagt tgtgatgtta gaattgaaat atttgaagga aagtttcatc 437880
aagtaaaaaa gatggttgag gtttgtggta aagaggtaat atatttaaaa cgcttatcga 437940
tccgcaatct tgaactggat aggagtttat cattgggtga ttttcgagaa ttatctaatg 438000
aggaattagt cgacttgatg gaggatttat gatagaatat ttttatatgt aaaggggagt 438060
aataatgcgt ttaagaaata atccaaaagc atatgatatt atgaaagaaa ataaatcttt 438120
tgtaatattg gagccggaaa attgtaaaaa taaatggaaa gatatttttg gaaataatca 438180
tccaatatat attgaaatcg ggatgggtaa aggtgatttt atttatgaaa atgctcgtca 438240
atttccagaa ataaattttg ttggtattga aaaataccca agtgttttag cagcagcaat 438300
aaataagata aatgctcgtg aagaaaaagt aaataatttg cgtttaatgc attacgatgc 438360
aattgaattg catcaagtat ttgaaaaaga tgaagttgat aaaatattct tgaattttag 438420
tgatccttgg cctaaaagta agcatgctaa aagacgactt acatcaagta aatttttaga 438480
tgtatacaag gatattttaa tagatgaagg aaatattgaa tttaaaagtg ataatcgtgg 438540
actgttcgaa tattcgatta tttctttaaa ccaatatcca atggatatag agtacattag 438600
tttagatttg cataacagtc ctgaaagtga aatcaatatt atgactgagt atgagcgaaa 438660
attttgtgag aaagggccaa tttataaatt ggtagcaagg tatcgtaaaa atggataaat 438720
tagtagaaat taaaacaatc gaagaatttg acaatattcg tgtaggtaaa acgattataa 438780
tgtttacagc agactggtgt cctgactgta tgtttgtaaa accgttcatt ggcgatattg 438840
ttgatgccaa tcctgaatac aagttttata tgattaatcg tgacaatatg attgatttgt 438900
gtaaggatct ggatatttta ggtattcctt cttttgtagc ttataacgat aaagaagaaa 438960
gtggacgctt tgtaagtaag ttacgtaaga ctaaagaaga aatacaggcg tttattgata 439020
cgttaaaata agaggtgtag gaatgatatt tcatggattt tataatttaa aacatgttgg 439080
tgatatttta ttagcacgat gtggagaagg taggaccttt gattatgata aatatgatga 439140
tttagtcgta ttgaaagata gtaaaaatag gatacttggt tttaatttgt tgaatgctag 439200
taattatttg ggagaattaa atactggact agttaatttt tcagataatc aaattgaaaa 439260
atttaatgaa cttttaacaa ctcacggact tgatccggtt gtcttagaca aagaacctcg 439320
ttttattgtt ggtgaggtaa ctgcaatgga agaacatcca gattctgacc acttacatat 439380
ttgtcaggtt gatttaaaga atactactac acaaattgta tgtggtgccc ctaatgttga 439440
agttgggcaa agagtggtag tagctactat tggcgcagtt atgcctagtg gattggttat 439500
taaaccttca aaactacgta aaattgattc taacgggatg atttgttcag caagagagtt 439560
aggactgcct aatgctcccc aaattagagg tatattagtt ttagataaag ataaatatag 439620
tattggagat tcatttttct agaaaagggg gaaacagtga tgtttagagg cttatttaaa 439680
aagcatgaag aagatgaaga tatttttgaa gtggatcctg tcgttgaaca gcgacgtaag 439740
gaaaaattta gcacgccatt aatatatgat gaagaattta aagaggagcc agaagtgact 439800
gtaacgccta ccccaaagac taaagaaaaa actaaggttg ttgaggcaaa gcctaaggta 439860
gaagaaaaac ctcgtcaaat ttaccaaatg agtgaagtta tttcaccaat gatgggaatt 439920
acaaaaggaa aaaatgataa aaaagctgta aagccaacaa cttcttcaaa acctaaaaaa 439980
cgtaaaaatg ttgatcaatt agttcctgta attagtcctt tttttggaaa ttatgaggaa 440040
aaggaacaag ttgaatcaga agcaaaactg acaactatta atgatgaacc taaagaaaaa 440100
aaagttattg aagatttgcc tacagtagaa gataatttac gtaatatagc taaaattgtg 440160
gaagaagaac aggatcagct taaaattatt gaggagcgaa ctggtgagtt caaattagat 440220
tttggtacta acgatgttga aaaacaaaac tctttgattg atgaaattga tgatgatatg 440280
tcattggatg aattaatgag tttgtatgaa aagaagttta aagactaaca atgataagtg 440340
gtattggttg tgatattgtt gatctaaatc ggctgaattt agataatgaa tgttttgttt 440400
taaaactatt aacaaaaaat gaatttttaa tttttaaaaa taaaaattct ttaaaacaaa 440460
aaaaagaatt tttgggtgga cgttttgctg ccaaagaagc tttttttaag gctcatggga 440520
ttgaacatgg catgctgtct tttcatgata ttgagatatt aaatgataaa aacggcaagc 440580
caaaaattaa ttatcctaat acttttattt caatcgctca tgaaaatgat tatgcaattg 440640
catatgttgt tgtagaagaa ggctaaattg ccttcttttt cagtatatat tggtaaattt 440700
attagataat tatagattag agcaataata agatatttgt aaaattagtt ttgaagattt 440760
tataaaatta ttatatagtt ggtatatgat tcttttatga gttacttgta attgggcaat 440820
aattatatac aagatacaat aaaaatattg caatattaaa tgaggtatat ttttattttc 440880
aacagttgtt ataatttcat tttttggtat aataacatac gtaaaatttc aagtttgtga 440940
taggaagcga aaatcatgta tgaagataaa gttaagaaaa gtcttagaaa aataattatt 441000
tttgcagtca ttattgggat atttttagca tcaattggag ctggattttt ctatgtgata 441060
agaacagctt ttgatcgttc aactgatgaa agaatgattg aagaaacaga taattataaa 441120
aagagattag ataaacaaat taataataat tttcaaatgt taaatactgt cgcaagcatt 441180
attggaaatt ctaatttgga tgagtctgct gattttgatt ccattttgga aagggcatat 441240
attgaaaatg atttcttgac agttgctttt ttttacaatg atgaaatggg aacactatct 441300
acaggtgatc atattatttc tagtgatatt catttatcgt cactacagcc tgaagtacaa 441360
gaagttgttc gtaaagcttt gcggggaaag gaaaatgttt cagaaccatt ctatggtgat 441420
ttttccgaag aagaggtttt tacttttggc gttccagtat atcgaaataa acaaattgtt 441480
ggagctatga ttgctagtag tgttgttgat gtattttcag aaattataga tggcgaaaag 441540
gtcttaaatg ggagtgctta tatccattta ttggatgtga atgggaaatt tttgattcgt 441600
tcctcacatg cagttgttaa agaaaaaaag actgatatat ttaaagaacc gtatttgtct 441660
ggagatgaat taacaaaaat taaaaaaagt atgaaaaatt ctgaaatagt ccgttttaca 441720
tttacctatg aaggaaaaga gtatcattca attttagaac cgcttgatgt taatgaatgg 441780
tatttgtttt gtattaactc tgttcaaaat agtaatagtg gaatttactc ggttgcttat 441840
gcagtagctt gtttctttgt cattatagtg ttactagtag gttatctttt aatttatggt 441900
tatcggacaa tgaaaaagaa taaccagcaa ttaatggatt ttgcatattt agatcgtcta 441960
acaggaattt ataatttaaa tcgttttggg gaattggcac accagcatat tgaagaacat 442020
tctgaatatg caattgctgc actaaatgta cgtaaattta aatttataaa tgagattttt 442080
ggaaaagaac aagcagatag gttactgtgc tacattggaa gaattttaaa tgataatatc 442140
aaagatggtg aacttgtctg tcgtgatagt gctgatgttt tttatatgtt tttattagag 442200
actgaaaaaa acattcttga agttcgtctt aaagaaattt tagaaaaaat cagaacgtca 442260
tcgaatgatt ctaatagtaa ttatagaatt actatgagtt gtggtattgc aacagctaca 442320
gacaagcagg aactacaagt gtcaatgaca catgcaatgt ttgccttaga aatatcgaaa 442380
aataatttta aaataccgct gtggtttttc gatgcggctt tacatgagca agaaaaaatg 442440
aatgactata tcgaaaggca tatgtacgaa gccatagaaa acggtgagtt taaattgtat 442500
ttacagccaa aaatagattt aaaaactaat tctcttgcta gtgctgaagc cttggtacgt 442560
tggataagaa acgatgggac tacaattttt ccctcacaat ttatcccaat ttttgaacag 442620
aatggatttt gtgttaattt agatatgtat atggttgaaa aggtttgcca attgcttcgc 442680
caatggattg acgaaggata tcaagctatt ccgattgcaa ttaatcaatc aaaattagta 442740
ctttatgaaa ttggatacgt aaagaatctt tgtggaatat tagatagata taatattcca 442800
gcatcattaa ttactttaga aattctggaa gaaattgcaa tcgaaaatgt agatgactta 442860
aataaaaaat taacagaatt aagagatatt ggttttaaaa tatctatgga tgactttgga 442920
acaggatatt cttcattaaa tactttagga aaattaaata ttgatgaatt aaaactggat 442980
cgtagctttt tagttgagat aaaggatact agaaatcaaa atgcacgttt aataatggag 443040
gaaattgttc aactatctaa gaaactttct atcttttctg ttattgaagg agtagaaaca 443100
agtgaagatg atttattggt taaagaaatt ggttgtgatt atggacaggg atactattat 443160
agtcgtccta ttgattcaaa tgattttaca agcaagatgc taaataagtt taataaataa 443220
ttttaattgg gagaatttta atggaaaatt tattaataga taatatgctg gaaaatgcta 443280
aaattggaat ttgggttatt gaattgtctc ataataaaaa gaatgaccct aaaatgtttg 443340
gtaatactca tatgaaatta ctgttaggag tagcggattc ttattcgccg gaggaagttt 443400
atcaattttg ggtagaacga atacatccag cttatgtttc ttatgtagag gaagcagttg 443460
aacgtttaat aagtgggaat aaggcagaag tcgaatatcc ttggaaacat cctgaaaatg 443520
gctggatgta tatacgatgt ggcgggtatc tcaatactaa ttttacacaa tgttatcgat 443580
tggaagggta tcatcaagat attagtaatt taattttccg tttcgaacca ttctcatttg 443640
attatcaaat tcaagatcaa cttttattta aagaatattc acgctattat atggatatat 443700
acgatgaatt atgtgaaatt gatccggtta cgaatacgat ggagattgtt tttcaacgaa 443760
aagataaata tttatccata ttttcgggaa ttaatttttt tgaatttata aaaaaatata 443820
tttattctat ggatcatctt atcatttgtg aaacttataa tgaattatct tcagcaaaaa 443880
aacaaaaagt gacgattgat gttcgtattc ataatagtaa tgatgggtat tcatggatac 443940
ggcttgtttt tgtactagca caaatgaact atagtcctaa agttttaatg ggaattatgg 444000
acattcaaga acaaaaacga aatatggagt tttttattga tagtgatgca atactctcaa 444060
cgattatcga ggaaaatgct tatatttttg atatagatat aatgacacaa aacatatctg 444120
ctattaaagg tgaaaattta tcaattcatg atatgtctta taacaaattt ttatctttat 444180
ttatgcagag atgcagtgat atttctgaat tagaatatct taatagtttt ttatcattta 444240
accatttaaa agaacttgtt tttcaaaaaa agaatgcaca tatcgatatc cgtgaaaaaa 444300
cagagcattt tctttatggc tggtatcgga tccatttaat ggttcctaaa gcattagaag 444360
accgtatttt aattctaatt aaaaaaatcg ataaagacga tgtatttcaa acggtaatta 444420
caaaatatgt acaaaagaat tttgaatcgc tctgttatat tgattgcgat agtggcaaat 444480
atttacaatt tgttactgaa ggaatgaagg aactaatttt taatgaaaat gaatttgatt 444540
ataaagatgc cttagataca tttattgaaa gtcaggtggt tatagaagat cgcaaagtag 444600
ctcaaactaa aatgaatctc gattatattt ttttaacttt gcaaaaagat ggcgactatt 444660
tttgtaatat acgaattttg gatagttgtg gagaatttca ccaaaaaaca atacactatt 444720
atatttatga tgaagataca aaaatcatat taatgatggt tgcagatacc acagaacaat 444780
atttattaaa tcaaagtgaa aaagagcaaa tagaaagatt aaagctaaaa gcaaatacag 444840
atgagttaac tggactatat aatcgatatt attgtaaaac acatattaat gaatatttac 444900
aagaagtacc tcaaggacag caggcggttt ttttattaat tgatctagat aattttaaaa 444960
atcttaacga ttctttagga catttagctg gtgatcaagc attagttgat gtagcaaatg 445020
ttttgaaaaa ttcattttgt gatgatgcta ttatttcacg ttttggagga gatgaatttg 445080
tggtttttgt aaaaaacatt caagacatca agctttttaa tcgtttaata tccagacttc 445140
ttcaacaatt agatttgtat tatcaaagtg aaaaggatca gataaacatc caagcttcta 445200
ttggaatagc actagcacct attgatggta gagatatgaa tactttatat ttaaaagcag 445260
ataaagcgtt gtatcaagca aaagaaggcg gaaaaaatag atacaagtat tacaataatt 445320
agttttgttt agataagatg ttaactaaat atttagccca atttaatatt aattgaactc 445380
tagcaaaata aattggaatt ctaaagataa agtatgtaca agcaagatga gttaaggtac 445440
tataatggag cataatcaaa aatatattta tttctgtgtt taagaaagta taagaaaata 445500
tcttttttat attgtcctca ttatgatggg gtgggaataa taaaaaatga atcttaattt 445560
gggaatatta aactctattt ttatagagtt ttttttgtta ttggaggtat tgaaaaatat 445620
tatataaaaa taaatatagt agttattttg ggcgaaacag ggataagatg gacttttttt 445680
gcaaaatatg tatatttttt tcgacaattt tttatagact gatatagtct atttaagcat 445740
atctgttaac ttttgctaca catctgaaag aaaaagtttc accagtgacc cattttgaca 445800
atgtcgttaa ttatggttaa ttttacagtg ttgtaatctt tttataatta tgcctataat 445860
tttgtcataa aggaggggta aataatgtta aatactgtag cattagtagg gagattagta 445920
gatatcccgg aaatgaaaac aacgattgga ggtgtaaaag tagcaaatgc aactattcaa 445980
atcgaacaag gttttaaaaa tagtcttggt gcatttgaaa atgattacat tgttgtaagt 446040
ttatggcgcg gtatcgctga aatgattatt gattgtgcaa gaccaggatg catgattgca 446100
gttaaaggaa gactgcattc gagaacatta gaatgtgccg agtcaaaaca aattacttca 446160
attgaagtaa ttgcagaacg agtttcttta ttagataaat atttcaaaaa ctatgattaa 446220
atatcatttg agtttaaccg gcttatttgt tataatgatt taacgaaagt gggtgaaaaa 446280
atgactattg atcaaagtaa aattagaaat ttttcaatta tcgcacatat cgatcatggt 446340
aaaagcaccc tagcagatcg aattttgcaa ataactggag ctgtcgcaga tcgtgaaatg 446400
aaggcacagt tactcgatag tatggattta gagcgagaaa gaggaattac catcaaatta 446460
aacgcagttc aactgaatta tactgctaaa gatggtcaaa catatttgtt acatttaatt 446520
gatacaccag gccatgtcga ctttacttat gaggtatcga gatcgttggc tgcttgtgaa 446580
ggtgcaatat tagttgttga ttcagtgcag ggagttgaag cacaaacgtt ggcaaatgtg 446640
tatttggctc tagataataa tttagaaata ttgccagtta ttaataaaat cgatttgcca 446700
agtgctgatc cgcaacgagt tatacgtgaa gttgaagaag ttattggttt gccggcagat 446760
catgcaccgt tgatttcagc aaagagcggt ttaaatgttg aagaagttct tgaaaaagtt 446820
gtacaggaat ttcctgctcc tagtggagat gtgaataatc caacacaagc tttgattttt 446880
gattcttatt atgatagtta tcgcggagta attgtatttg ttagggttaa agaaggaact 446940
attaacgttg gagatcatgt gaagtttatg gcaacaggag caacatatga agtaactgaa 447000
ttaggtgtaa gaactcctcg tgaagtaaaa aaagaacagt tagtggtagg tgaagtaggc 447060
tggtttgccg cttcaataaa atccatccag gatattcatg tgggggatac tgtaactaca 447120
gttgaaaatg agtctaatat tcaattaccc ggataccgcc aattaaatcc gatggtatat 447180
tgtggtttat atcctgttga taacgctcgt tataaagatt tacgggaagc gttagaaaaa 447240
atgaaattaa gtgattcatc attaatgttt gatccagaaa cctcacaagc attaggattt 447300
ggatttagat gtggtttttt aggcttgttg catatggatg ttattcaaga acgtttagaa 447360
agagaatttg atcttgattt aattgcaacg gcaccatcag ttatttatca ttgctatttg 447420
acagatcgta gtgaagtaat cgttgataat ccagcgatga tgcctgagcc gcaagtaatt 447480
gatcatattg aagaacctta tgttaaagct tctattatga ctccaaacga atacgtaggg 447540
gttatcatgg aattatgtca atctaaacgt ggagaatatc aggatattga atatattgat 447600
gatactcgac gtaatgtaat ttatgaaatt cctttatctg aaattgtata tgattttttt 447660
gacaaattaa aatcaggtac taaaggctat gcatctcttg attatgaatt gattggctat 447720
cgtactagca aacttcaaaa aatggatatt ttattgaacg gagaagtcgt tgatgcactt 447780
tcaacaattg tgcataagga ttttgcatat ggacgaggaa aaattatctg tgaaaaatta 447840
aaagaaatta ttccaaaaca aatgtttgaa gtgccaattc aagcagcact acaagggaaa 447900
ataattgccc gtactacaat taaggcgatg cgtaaaaatg tattggcaaa atgttatggc 447960
ggcgatattt ctcgtaaaaa gaaattacta gagaaacaaa aagaaggtaa aaaacgaatg 448020
aaggcagttg gaaatgttga aattccacaa gaggcattca tggcgatatt atctgttgac 448080
gatgagtagg ataaattatc tatcctactt atttttttgt tgtaaatagt cttgatagcc 448140
attacaatat aaatatatac gaataaagga gaatgaaaat gacaatcaaa ttaccagaca 448200
attttttctt tggggcggct ttatctggtc cgcaaactga aggtgcttat aacgttggtg 448260
gtcgcctaag atcatactgg gacatgtggt ctgaccagga aatcaatgct tttcataaca 448320
atgttggctc atatgtcgga aatgatatgt atcaccgtta tgaagaagac atcaaactgt 448380
tcaaatcaat gaactttaaa tcttttagaa catcaatgca gtggactaga ctgcttgatc 448440
aggatggaaa tattaatcca gaaggagctg catggtatca taaactgatc gattgtgcca 448500
atgaaaacgg aatcgatatc tttatgaaca tgtatcattt cgatatgcct gaatatttat 448560
ataaacgtgg tggttgggct aatcgtgaag ttgttgaagc ttatgcaaat tttgttaaaa 448620
aggcaatgga ggaatttggt ggcaaagtta aatattggtt tacattcaat gagccaatcg 448680
ttgaaccaga acagcaatat ttgcatgggg tttggtttcc ctatgaaaag aacattaaac 448740
gttcattgga tgtccaatat aatatcacat tagcacactg tctagcagta atgaacttta 448800
gagaactgca ggctgaaggg aaaatggttg aaggagcgaa gatagggatg attaactgct 448860
ttgcaccacc atatacaaaa gaagatccaa gtccagagga tctggaagca gtaagaatga 448920
cagatgggtt gcataaccgc tggtggttag atgtagtagc acacggacat ctgccaaagg 448980
atgtaattga tacagtagaa aatgaatgga agatcaaaat gaatcgtcgc cctggagatg 449040
aagcaatctt agctggagga aaagtagatt ggttgggatt taattattac cagccgacaa 449100
gaattcaggc gccagatcag aaatttgatg aaaatggatt gccatgtata gcgaaaccat 449160
atatctggcc agagagaaga atgaacgaac accgtggctg ggagatttat ccgaaaggaa 449220
tctatgattt tgggatgaag attaaaaatg aatgtccgga tctgccttat ttcatatcag 449280
aaaatggaat gggggtagaa ggagaagaaa aatatatgga tgagaatgga tcggtacagg 449340
atgattatcg aatagaattt gtaagggatc atctggaatg gattgcaaaa gcaatagaag 449400
atggatcaaa ctgtttagga tatcattact ggggagtaat agacaactgg tcatgggcaa 449460
atgcttttaa aaatcgttac ggattcattc gtgtagcatt agatcaggga tacaagagaa 449520
ttgaaaagaa gagtgctaac tggataagag aagtagcgaa gaataatgaa ttcgagtagg 449580
aagtgagtaa tcacttcctt tattttttat taataatatt ttaatgtact atctaattat 449640
tatagtttat aattaataac gaatagggtg atatctctaa ttgttgtatt aatatttttt 449700
attattagga aattagtaac atgttttgtc tttaatcaat gatattttaa tttttaaaac 449760
ctattttgtc ataaaatatt ttaataaaat tatggcagtt atttttactt tgtggtaaat 449820
tttgttttta atttacttac aagtaaattt gttttataat gaacaaatga taaggaggcg 449880
tagaaatggc atttaatttt cgaaataaaa tacctaaggt acgtttttat ggggcgtcag 449940
aacaagaacg tgaacaaaaa aatttacaag ataacattgt tagtcggcga ttaatcggac 450000
tactttgttt tgttattgct gttacttccg taatggcaat acgtttagga attatacaat 450060
ttaaacaggc tgatgaattg gcagtaaagc tggaacaata tggtactact acatatacga 450120
gtgatgctcc tagaggagaa attgttgacc gtgaatatgt aaaattagtg gaaaatacaa 450180
gtgtaatttg tgcaacatat tatgcaccta aaaaaattga taatgatgtt ttaaaagaat 450240
cagctgcttt tttagcaaaa aatatcaata ttgatgtaaa tgataaaaaa atcatttctg 450300
atcgagcaaa aaaggattat tttattttag cttttaaaga tgttgctgac ggattgatta 450360
gcgataaaga aaaagaagaa atcaaagctc aagaaaatgc agacaaaaga ttatatagtc 450420
ttaaattaga gagaattact gatgaattaa ttagtcaata tatggatgaa gcaacattaa 450480
aatatactca ctttttatac ttgatgcaaa attgtacgag tggttcgtca attttggctg 450540
aaggtttaac tgatgaggag gctagtatta ttggtgaaaa tgcagatatc ttacccgggg 450600
tgacagttac aacagattgg gcacgtcaat attcaaattc aacagagttt gcttcagttt 450660
taggcaaagt gacgactaaa aaacaagggt tacctgtaga attaaaaaat gaattattag 450720
cattgggata ccaaaatgat tctagagtag gaacttcggg cttagaggag cagtatgaag 450780
atattttacg agggaatgac agtacctata ccttaaatta tgatagctca ggaaacccaa 450840
taataacaag tactaaagca ggaactgcag gttcaaatat tcgtatttca attgattggg 450900
aacttcaaca attggctaat caaaaaatcg aagaggaatt aaaagcttgt aatagcagta 450960
ataaatattt taataaaatg ttttttattc taatggatcc atatacgggt gaaattattg 451020
taatggccgg caaaacaatc gataaagcaa ctggtgaagt tagtgattat gcttcaggga 451080
attacctaga tgcaaataaa atcggttcaa caattaaggg aggttcaatt tatactggtt 451140
tcaaagaagg agtaattgga ccaaacactt attttgttga tgagccaatc aaaattaaag 451200
gaacaaaagc taaaaagtct tggaaatctt ttggaactat taatgaagtt gatgctctgg 451260
cttattcatc aaatgtttat atgtttagga tagcaatgct tttaggtggg gcaaattatg 451320
tttatgatgg gccgttgaaa ataaatgaag aagcttttga tactttaaga aatgatttag 451380
gtgagttagg gttaggagtt aaaacaggat tagatgtttc aaatgaagca ttaggatatc 451440
gaggaaaaca acgtacaggt gggttgttat tagatgcaat gattggtcag tatgatactt 451500
acacaaatat tcaattagca caatacgcat gtacattggc taatggcggg aaaagaatcc 451560
agccccactt acttttagac tcatatacta ctgatgagga tggagaaata caagttaatt 451620
atgaggcaaa tacaaatgta ttagatgatg ttagtaatca agcgacggcg tttagccaaa 451680
ttaaacaagg aatgagagct tgtgttaccc gaactgaagg aactgcacat tcttggaatt 451740
caaaaccata tgtaacttat gctaaaaccg gaacagcaga agattataca actgatgatg 451800
gtaagactgg aacaaccgat tatcctaatc atttacaaat aggttatgtg caaacaacgg 451860
aggattctag accagaagtt gcttttgctt gtatgagtta tcgacaaact actgcaacaa 451920
gtggatctag ttctgctccg atcgttgctc aagcagtaat tgatcgttac tgggagaagt 451980
atcactcaac aaattaaaaa aagtgctagt aattatttaa atactatgat aatatattag 452040
acggaagttt actaatggag gtgtaactaa tgagagaaaa tatcatttat aaatgtactg 452100
aatgtggtga agaaaactat atcaacacaa aaaataaaag aaatcatcca gatagaatgg 452160
aaatcaacaa atactgtcca agatgtaata aaaaaactgt acataaagaa aagaaataag 452220
ccttattggc tttttttctt tataggagga agaagatgaa aataaaaaca ttactgctag 452280
gtaatatgca aactaatggc tatgtggtaa gtgatgagaa tcatcattgc ttaatcattg 452340
atcctggagc taatggtaag aaagttgtgc attatttgac ggaaaatgaa ctagttccag 452400
aagctgtttt attaactcat ggacatttcg atcatattgg tgcggttgac tatttatacg 452460
aacattacca ctgtcctatc tatcttcatc aagacgattt agaaatgcta gataatcctc 452520
agttaaattt atcagtgtat gaaaatcctt ttactgttaa agcaccagtt cagtcaagcc 452580
atgaggagat gaagtttggg gattttgatg tacaatggct acatttacca ggacattgtc 452640
caggatcgtc aatgatttat ttaaaagatg aaaatataat tttttctgga gatgtattgt 452700
ttaaagggtc aattggacgc tttgattttc caaattcatc aaagtatgaa acaatcgaaa 452760
gcataaataa aataaaggaa tatgattttg atgctgttat ttatcctggt catggaccaa 452820
actctacgtt aagtgaagaa cgcctaaata atccatattt aaaaaagtcg taatttttat 452880
agtgaactgc ctttgttgga caaaaaataa tttaaattaa ttgtaaggct tgattcctaa 452940
tttgtatagg ggttaagcct tttcttttta ctgtaattat agaattatta tggtattcga 453000
tataatctat aatatcttgt tttaactctt ctaatgattt gaatgtatct tcaaatccat 453060
aaaacatttc attcttcatt ttttccaaga agttttctat tagtaaatta tcctgaccgt 453120
tccctttcga gactttgatt aagtaattcc tttttctttt aatttatttt aatatgagaa 453180
atgttggtac tgccatcctt gattactatg gaaaaattta gagaaagcca tatctaacat 453240
tcggtatgtt tgaaatagac ttggtgtagt tgatatatcg tatcctacga tttttctact 453300
atgcatatct aaaattggag ataaatataa tttactcata gctgttttaa aatcagaaac 453360
atcagttgtc catttttgat taaccgatgt agttttaagg tttctattaa aatatgtttt 453420
tctaatatac ttattctctc gtttatcaag aagtaagttc ttacaagttc cattcatttc 453480
ccccttatag gagttataac gttgcttagg agtaggatta agtgcatata aacccatatg 453540
tgacatagta ccactattct ttgtttattc gtaagtttgg acatataaaa agtgaaccga 453600
ataggttgga caacttattc ggttcgctat aattttttac gattttttta ataattcaat 453660
tattgtagta ttttacaata atgcgtgttg atcgctgtga gtttatttta ggaaagaatc 453720
tcatggttga aataataaaa aatgagtcat gatataatta tcttagtgta aatatattgc 453780
aacttgatat tctactagct tatataatta atgaatatat taacttttct gcccgcatgc 453840
tctttcaaat tataaaacct gcttgcaaaa aatgaaagca gcttgcataa aggaatgtgg 453900
cgttcttatt ccttcttcgg atagaatgtt agtgaaagga agggataaca tgaataaaaa 453960
gaatttgtta ttgtcagtgg cattatcagg aactatgcta atgtccaatg gtattaccgc 454020
attaacggct caaaatgctg tatatagtcc gggcgtaacg gtagagaaaa atactaatcc 454080
agactgggat gccgattata ccgcaacctt tgtttatgaa gacaaagatg cacgtgacgc 454140
agaaagagta acagtttcag gtaattttca gttttactca ttaaatgatc cggttgttaa 454200
aaattatgaa aaaacagctg atcctaccgg agccaaggtt tacagtgctt atgactatga 454260
taaggataac gcaatgttca atgtaagtag cggacaaaat aacgatacac ccatttatga 454320
actggaggaa acaggagacg aaagattcga gattacactg ccgttaccgg gcaatcagta 454380
tttttatgat tatacagtag agtatagtga cggttcaaaa gttacgattc aggatccggt 454440
aaatccatca aagaaaaaca gcttaactga tcatgattcg ggacacagtg ttttctatgt 454500
tggaaacagt gaaaatacaa cagcaggaca ggagtatatt tatccaagag ctgacggtca 454560
aacagggaaa tatgaattta ttgaatacaa ggatgcacat aacacagatg aagaaacaca 454620
gtcattaggt gtttatctac catacaacta tgatccttca aaaacatata aaacgattta 454680
tgtatcacat ggcggtggcg gaaatgaagc cgaatggatg gaaattggtt cattgccaaa 454740
tattatggat aatatccttg cggaaaaaga agcagcagaa agtgttgttg taacaatgga 454800
taacagtcac tttggatggg attatgattt aattgcgaaa aatttcaaag aaaatatcat 454860
tccgctgatt gaagagagat acagcgtatc tacgaaagtg gaggacagag cgctgtgtgg 454920
tctatcaatg ggagcattga caacagggac aatcatgttc agttatacag acatgtttgg 454980
agcgtatgga aatttttcag ggacagcaga tccactgatt tgtaaagact gggagttatt 455040
aaaaacaaag acagtatatc taactggcgg gaatctagat atggctattc aggcgacgca 455100
ggaatctgga gattcagcat ttaacagagg gaagacagta agagcacatg aatatttaga 455160
agagctggga gtagagcatt tttatgattt aaaatacggt tcacatgact ggggcgtatg 455220
gagagatgca tttacaacat ttgttaaaga tattttatgg ggttatgaat atcctggaga 455280
atctacttat caagccggtg tgacagtaga agaaaacatt aatccagcat atgatggtga 455340
ttatataaca acttttgtat acgaagatca agatatcaag gatgcggtca aggtaactgt 455400
ttcaggaaat ttacaattct attctaaaga tgatgaagcg gttaaaaact atactcagac 455460
tttagatttt tcacaagcaa aagtatataa tgcttacgag tataaagatg gaatgtttaa 455520
tactggctat gggttaaata atgatactgc catttatgaa ttgacagaga caaaagatga 455580
acgttttgaa attactttac cattaccagg gaatctttac tactatgact atacagttac 455640
ttatgctgac ggcactacag taacaattca agatccagca aatccgtcac taaaaaatga 455700
ctacaataat catgatgctg gccacagttt ggtgtatgtt ggttcttcaa agaatactat 455760
tgatggacaa gaatatgttt atgctagaga tgataatcaa aaaggaacat attcattcgt 455820
aaattatgat gcgattgatg gaacaaaaca accattaggt atatatctac catataacta 455880
tgatgctact aaaagctata aaactattta tgtatcacac ggtggcggtg gtaatgaagt 455940
tgaatggatg acaattggtg cggttccaaa tataatgaat aatttattag ctgataaaga 456000
agtagctgaa gcaattgttg taacaatgga taatacatat tttggttggg actacgatca 456060
aattaaaaat aacttaatga atcatattat tccatttatt gaagctaact atagtgtttc 456120
aactatcagc aatgatcgtg cattctgtgg attatctatg ggtggtctta caacaacgtc 456180
tatttatacg accttagcag ataaatttgg atatttagga atttggtcag caactgatcc 456240
aaatactgat atatcagcaa taaaaaatgc ggacaaacca acattattat tagcagctgg 456300
tattgttgat tatggtaaag ttggatttac aggaaataaa gattttgcag gattattagc 456360
aaatctagat gaagcaggca ttaaatatga ttatattgaa acttatggtg ctcatgactg 456420
gggaacatgg cgtagtctgt ttacaacatt tgtaaaagac tatttatggg atattaaaga 456480
agtaaaggat gagccaacag taaatcctgg agatacgaca aaaccggttg taagtgtaaa 456540
aactggtgat aatgttgata taaatggact gttactcatt tctggactat cattattagg 456600
tatttctatt caatactatt gtaaggctca tagaggacat taaaagacta tatattttga 456660
agcgaacccc aaaagttgga cataaccaac gtgaggggtt tttattatgg taaagttaac 456720
gagaaaaaag atgctataat ttatagagag ggattacaaa acccgctata aattataatg 456780
agagattatg aagataatcc ataatctctt taaagtatag tggggaaaat gtccggatta 456840
tcattccttt cactttttta ttttgtggac taatagaata agattcatat ttattttgtg 456900
aataaatatt atccttttta ttgacctaaa ccttagggca taatatgtaa taagcgcaag 456960
gagaatgaat gctatgaaga ccatgaagtt gaagagtggt ttcatattac caagaaagca 457020
ctcatatatt atgaaaaagt tggtttaata aaaccagata gagatgataa tgactaccga 457080
aattatagtc aaagcgatgc tgatagtgtg aaacttattg tatttttaag atcaatgaaa 457140
atatcactag aagaaataaa aaaatcaata tatcaatgta tagcagattg ggaaaaagat 457200
ggacgataca atcatgtcgc ttttgtagtc gcatctggaa gtaaaatatc tagcgggtat 457260
gatgatgtaa caattgcaca acatacaagt aactgttgtg ctagagtaac ctctttcgta 457320
accggattgg gaaatacctc tgcagtataa aatttacaat cgaagaacta cgaatgagaa 457380
tatagaaatt gaaaaatagt tacttgcaga ttctagtact agataagagt ataaaatata 457440
ggcgctttaa aataatgtag ggtgcctaac aaaaagtagg gttggaagat gtaatgtctt 457500
cattaataac cctatttttt atgtgtctag atatattatc caatttatat tttatttaga 457560
tttgttttgc ttaaaaggtt agaataatcg tattttttta ttttttaaaa gtaatttcta 457620
tattacaggc gtaaatgata ataggaggta tttttatgga tgaactattt gaaaaaatct 457680
taaatcatgc aattaattat aagacatcag atattcatat tttaatgaag caaaaatgtt 457740
ctatttcttt tcggcaacat ggtgatttgg tattatatga tacatttgaa agtcatatcg 457800
gattaaaatt atttaattat attcgtttca agtcaaatat agatattaat tatcgtttac 457860
gaccacaaac gggtcattta aattatattt atcaaaatca aatttactat ttacgaatat 457920
ctagtttacc tggtagagaa ttagatagta ttgtaattag aattttaaac aatcatcaac 457980
aaattgccct tgataaattg actattttta aagaaacaac tgttttttta aaacatatca 458040
cgactttaga agccggacta tttattgtaa gtggagcaac tggttcagga aagtcaacca 458100
cactatatac cctactagat tcaattaacg ctactcaaca aagaaatatt gtcactcttg 458160
aagatccagt cgaaataaaa aaggagtatt gcttgcaaat tcaaataaac gaaaaactag 458220
gaattacata taataactct ttaaaacaaa tcttacgcca tgatcctgat gtaataatga 458280
taggtgaaat acgcgatgag caaactgctc gtctagctgt tacatgtgca ttaacaggcc 458340
atttagtatt aacaacaatc cattcgtcaa attgccttac aacaatcaga cgtcttttaa 458400
acttaggact tttaaaaatt gatatagagg atgttttaat tggcataata tgccaaaaaa 458460
tgctctatca caagtataca catcagccct taattttacc agaatattta aatcgtcaaa 458520
aaattttaac ttttttcaat aatgaacctg ttaagtatca aacatttgaa atgaatgcaa 458580
aatatttatt aaaaaataat ttagttgatt atacacaggt tgcaggaatt atttatgaat 458640
gatgatttac aattattaga aaatatcgct aactttttaa aacaaggtta tttaatcaaa 458700
gatgttttaa atttatgtct gataatccat caaactgaaa aaataaagct gattgaacaa 458760
aatttggttg ctggtaaagc atttgatgag gttattatag aaattgattt tgacaataca 458820
tttattgaat actttaaatt ttttcgattt aaaaataata tttcaactgc aattgagcat 458880
agcttaaaaa tatgcagaaa aaaggaacaa atatttacac agctaaaaaa agaattaacg 458940
tatccagttt tactcattat ttttttaatg tttttttcat tgtttattgt atatggatta 459000
ttaccatcaa tcatgcaatt gtttgtcgaa tttaatatta gtccaagtat tataactaga 459060
attatattta agctttttga aattattcca attatagtaa ttttcattat acttagtttt 459120
acagtatttt tcacaataag tatttatgct attaaaagaa aatattttaa acttattgat 459180
ttgttaattg aaaaaatagt tttaataaga aggttaatcc aaaaatacta ttcactaaaa 459240
tttgctctgt attataatga attactgatc aatggctatg attcaactga tattattgtc 459300
atgctttatg agcaaataga tgatagtgat attaaaatga taatttacga aatttatcga 459360
caagttttag aaggagaagc tttagaggat ataataaatg attttgaata ttttgaacca 459420
ttatttatag catattttaa attattaatt catgataatc aaaaagataa atcactcgat 459480
aattatttaa gggtatctat tgatactttg catatgcagg taacgagatt gattaaactc 459540
tttgtaccaa taatatattg ttttgtggct ggttttgtaa ttttagttta tgttgcaatt 459600
gttattccga tgatgaatgt agtcagtaat ttataggagg tatgaaagat gaaaaggaat 459660
aatggcttta cattgattga gatgattttt tgtatttcag taattttagt tattttgtta 459720
cttgttattc ctaatgtaac tagtaagaat cgggttgtta aagaaaagag ttgtgatgcg 459780
caaatagaag tagttaattc acaaatagtt ttatacgaaa ttgaaaacgg agaacttcca 459840
acaagtatta gtgatttgac ttctggagaa catccatatt tgacagaaaa gcaggcaaca 459900
tgtccaagcg gacttaggat ttcaatcagt gatggacaag catatgtacg atgatagcgg 459960
attcactctg attgaagttg tctttacaat tagtataatc ttaattttaa gtacaattac 460020
acttcatttt gtaattaatt caaaaccagt aatttcttta cagcagcaat gtcaacaggt 460080
aatttcattg ttagaagaag gaaaaagtag agctatgatc aaccacgagc aaataaatat 460140
agttattcaa acaaaacaaa ttagttataa tggacaaaag gatcaacgaa ctcttacgat 460200
taacgacaac tattatattg acgattatta tgagtttcac tttaatcata atggaaatat 460260
cagttcgggt ggtcatctaa agatttgtag ttcaaatgga tgtaaaagta taattttaaa 460320
tgttggaagt ggagcatttt atgttaaata agcaagggat gacattaatt gaaacattga 460380
tggctttttc tatttttatc agtattatag tattgtttct ttcttgttat aataatgcaa 460440
taaatcatca ttatcagatt aatcaggatt atatgaacta tttaaaacag caacaagaaa 460500
aggaggtaga gctgtggcag acaagtggtt tgagcgaatc agtcaacgag gttttacatt 460560
gattgaagtt cttttttctt tatcaatatg tttattaatt attttaaaca gtgtccccat 460620
tttaagaata gttactgcaa aagataaatt atcctttaat ctttctagtt atgctcttgg 460680
agttaaacaa atttcatcaa ttttgcatac ggctaaggat attgaaatca atgatgattt 460740
aacttacaca aatgcaaata acgaaatctt tactatttca ctaaatcatc ataggatagt 460800
aaaagagcca ggttttgata tcattataca caatgttgat gaattaaatt tttatcaaaa 460860
aaataagaat atttatatga aaataatagt cgataataaa gaacatgttt atcttattgc 460920
tactgattat caaataagtg agaatgaaaa agatgaagtt gaaacagtat tgtaataatc 460980
ggggtacgat tcttcaagtc gtgttagtta tttttattgt tttaatctta aacataagtc 461040
ttgtttttaa taatataata gagaatagcc gcagtctaga acgaatcaga gaattagata 461100
gggcacgttt gttggaaata acaatactga gatattataa agaaacaatt ttaaatgatc 461160
ttctttttag tgatgaaata agtattgatg attatttcat taattataca gtggatgata 461220
tggggagtta ctattatatt gttacaacaa tcaaacaaaa tgattcatca tacagtttta 461280
atttggagat taatatcgaa acgctagtaa tatcatcgtt tgattatcaa tagttactaa 461340
aatcacttca ctttatcgat gatttttgat ataatcacaa agtaaattac aagtaaggag 461400
attttaaaat gattagtgtt ggagatttaa gaccaggaat tacttttgaa tatgaaggta 461460
acttatatgt agtgcttgat tattctcata ataaaacagc tcgtgcggct gcaaatatca 461520
aagttaaaat gaaaaatatg cgttctggag caactactga aattactttt ggtggaaatg 461580
ataaagtaaa aaaagcacat atcgataaac gtaaaatgca atatttatat aattcaggag 461640
atgctttagt tttcatggat aatgaaactt acgaacaaat cgaaattcct gctggaaact 461700
tagaatggga aatgaatttc ttaaaagaaa gtgatgaagt tgaagtaact agttatgaag 461760
gagaagtatt aggggtatct ttaccaatta atgtaccttt cactattaca gaaactgaac 461820
cagcagtaaa aggtgataca gctactgggg caacaaaaaa tgcaattatc gaaactggat 461880
ttcaaattaa agtaccttta tttatttctg aaggtgaagt tgtcattgtt aatacggttg 461940
atggaaaata tcaaggaaga gcttaacact agtttaacta gtgttttttt tcatatattt 462000
taacttttag catatattaa agtagttgat aaaaggagaa ataatatgaa tagacaagcc 462060
attacttttt taaccctatt tagtctaatt ttggtacttt caatttacta tattcttcta 462120
ccacctgaag gtgaagccag tgaagtatct gttaataatg aagaattatc gcaaattgaa 462180
gtattacaac aaaatttaga aaaagaaaga gcagatttaa ttagtgaaaa taatgcaatt 462240
attgcatcaa gtgatagcga tagtaataaa atcgctgctg ctttggctaa tattagtgaa 462300
gctaaagaaa ctgctgcttt agaagcaaaa attacaaaga taattaatga tgctggtttt 462360
aagaatgcat ttgttgaggt tgagaataaa acgattaaag tagttattga taaaaaggaa 462420
gcaagtagta gtgatgctaa cagtattatt aaaacagtta tggaaaagac taaaaatgag 462480
tatcaagttg aagtcaagtt tatcagtgag acttgaattt tatcttaaat ttatatacaa 462540
tgggagtata taaaggagca tttaatatga gtcaagaata ttattcagta gaaaaagaat 462600
ctaatttagg agctttaaat attggtttga gcgtttttca agctatagtt gtaaaagcag 462660
ttgagtcagt tgatggtgtt caatttgaag gaaatatgat cccaatgcct ggaagtgggc 462720
cagttagaac aaatattaat aaaaataacc aagtaattat tgatgttgat gtactaattg 462780
attatggatt gaatgttgca tcagtgacta gtgccttaca aaataaaata gctcaaagct 462840
gttttgaaat gacaggaatc aaaaatgtta aagtaaatat tgaagttaaa ggaattaatt 462900
tttaaggtta tcttcggata atcttttttg ttttattatg atgcatttcg tttattttaa 462960
agtgcaaata tggtaaaatc atgatagata ttttggaagg acggattaga tgaaaaaata 463020
tagaaaaaaa ataattagag aaaaagcagt aattgcaact tatcaaaaac tgctagtaga 463080
tacaaatgaa gatgagattc gtgaatattt aaacagtgat aaggatttat ctagcaatca 463140
agatgatttt gattattgtt ttatgtttat tataagtatt gctagtaaca ttgaacgtta 463200
taaagctgaa gttgctaaat atttaaaacc cggatggacg ttagatagat tatcaaaaat 463260
ggaacttgca attttattag ttggatgtta tgaactttta gaaactgaac aaagtaaaga 463320
agtaatcatt aatgaagcgg ttgaattatc aaaaaaatat tgtgatagtg atgcttataa 463380
attcattaat ggattactta ataggattaa atagtggaaa aacgatatct gacggttagt 463440
gcacttaatc gttatttaaa agctaaaatt gattctgata gtcaattaca gcgaatctta 463500
atcaaaggtg aggtttctaa ttttaaacat catagttcag gacattttta ttttacgcta 463560
aaagatgagc attcaagaat aaatgcagta atgttctctt caaaagctag taaagttcct 463620
tttgatttga ccaatgggat gaaagtactt gttcaagcta gtgtgtcagt atatgatgta 463680
gcaggcacct atcaattgta tgttgataca attgaacaag atggattagg aaatttattt 463740
ttaaaatatg aacaattaaa aaagcagtta gctagcgaag gtttatttaa ccctgaaaat 463800
aaattagtaa ttcctaaatt tcctagtaag attgcagttt tgtcagccta tcctagtgct 463860
gctcttgctg atattattag aaccattcac ttgcgttttc ctgtcgttcg tgtaatcgta 463920
tttccaattc cagtccaggg taaggatgca tatttggaaa taattagaac acttagatat 463980
gttgatacac taggatttag tgaaattatt attgcaagag gcggaggttc attagaagac 464040
ttatggaact tcaacgagga aggattagct cgagcaattt atcaatgtaa gacacctatt 464100
attagcggtg ttggtcatga agttgatttt actatttgtg attttgttgc agattatcgt 464160
gctgcaacac caacggctgc ggcaattaaa gcaacaccgg acttatttga attacagcag 464220
gctgtagaca atataaaata tactttaaat aatttaatga aacaaaaaat tatattaaat 464280
aaagaaaatt taaatcgatt aaagtcattc tatttattta aaaatcctca aaaaatgttt 464340
gaagataaga cggctaaaat tgattattta tatgatcaat taaataatgt ttttaaccat 464400
gatttgattg aaaaacaaaa caaagcaagc aatttaatac aaacttttaa tcatcaagcc 464460
aatttattta cactaaatca gcgaaatcgt ttagatacaa ttaatcgaac gatgagtctt 464520
gagattaaac gtaaattaca acataatcaa gaaaagtttt attattcatt atcaaaatta 464580
aatactttat caccccttaa aacattagaa cgtggttatg caattgtttt aaaagaagat 464640
catgttattt catcagttga tgatttaaat agtggtgata aaattgaatt aaaattacat 464700
aatggcatta aaaaggccat tatagaatag aggttaattt atggacaata taacatttga 464760
acaagcaatg agtcgcttag aagaaattat tgcggctctc gaaaataacc aaatatcact 464820
tgaaaaaagt gtagatttat ttcaagaggg aataaaacta tcaaagattt gtagtgataa 464880
gttagctaga attgaagata aagtagcaaa aatcttagtg gatggaaagt tagaagatct 464940
aaaaatcgag gaataacatg gaaaatttaa ttgaacaaat taatgaacga ttattagaaa 465000
tcattgagga atttggcgat tctaaagtta aagaagccat gaaatattct ttgatggccg 465060
gtggaaaaag gattcgtccg gtaatgatgc tgcaggtgat tcgtagttat gataaaaatt 465120
accaagatta tctagatatt gcttgtgcaa ttgagatgat acatacgtat tcattgattc 465180
atgatgattt accaggtatg gataatgatg atttaagacg tgggcgacta acttgtcata 465240
aacaatttga tgaagcaact gccattttag ctggcgatgc attattgaat gaagctgtta 465300
atgtaattat taaaacaaaa gttcctgatg aattaaaaat ctcgttgtta gcaactttat 465360
atcaagccag cggtattaac ggaatgattt tagggcaagc attggatatg gaatacgaaa 465420
ctaaattggc tactcgtgat cagttagatt tgattcatca ccataaaaca ggagacttaa 465480
tcagtgcagc gatgaaaatg ggagcgttaa ttgctaatcc cgatgaccaa aaaacatggg 465540
tagaaatcgg ttataagatt ggtttagctt ttcaaattca agatgatgtt ttagatgtag 465600
ttggtgatag tagtttatta ggaaaaaaag ttggtagtga tcaagtaaat cataaatcta 465660
catatgtaac tttgatggga gtagaacaat ctcaaatgat tgttgagcaa tattttaaag 465720
aagcaatgga attaatttat aaattaaaga ttaatcatgg attaattcta gaaataatgg 465780
aaaaattaaa gaaaagagtg aaataatgga tctagaaaaa attacagatc cctctttttt 465840
aaaagagctg gatattagac aattgaatca attagccgat gatatccgca aatttttgat 465900
taataatatt tcaaaaacgg gaggacatct ttcgagtaac ttaggagttg tagaattgag 465960
cattgcactg cattatgttt ttaattcccc taaagataaa attttctttg atgtaggaca 466020
ccagtcttat gttcataaaa ttttaacggg acgtgctggt caattttcta cactacgcca 466080
atataaggga ctttcaggct ttcaaaagcg ttgtgaaagt gaacatgacc cttgggaagc 466140
tggtcattcc tcaactgcat taagcggggc cttgggaatg gcagtagcaa gagacttgaa 466200
tcatgaaaat tatcatattt tacctgtgat tggcgatgct gcaatggttg ggggtgaatc 466260
tttagaagca ttaaatcatc ttggctcaat taataataaa gtgattatta ttttaaatga 466320
caaccaaatg gcaattggta aaagtgttgg tggttttggt gattttttat cttcaataag 466380
aattagtggt acatataata atttaaaaga ggattatcgc aatattactt cgcacaataa 466440
aataggtaag atgattttta atgtttccaa acgagttaaa gattttgtta agcatggatt 466500
gattgatgat acaatttttg aagattttgg ggttgattat ctgggtccgg taaatggtca 466560
tgattttgat gatctaatta gggttttaaa tttagctaaa agtgcaaaaa ctagtgttgt 466620
agttcacgtg gttacgaaaa aagggcgtgg ctataaatac gccgaaaatg atattgccgg 466680
taaatggcat gggattgccc cattcaatat tgaagacgga actatgaaag gtgcgggaac 466740
tagttcgaaa ataagttggt caaaaatggt tgctgatcat attgaaaggc agatgaaatc 466800
agatcaggat attgttgcta ttacccctgc catgattcat ggttctgcaa tggataatat 466860
ttttatgcat tatcctgagc gaagttttga tgttggaatt gctgaagagc atgctttgac 466920
ttttacagca gggttagcaa tttctcaaaa aaagccattt atttctatct attcttcatt 466980
tttacaacgt gcatatgatc aaataaatca tgatattgca agaatggatc tgggctgctt 467040
gatttgtgtt gatcgctgtg gatttgttgg agcagacgga cctacacatc atggtgtttt 467100
tgatttagga atattaacac ctctgccaaa tgtaataatt tgtactccaa gtaatagtta 467160
tgatgctaaa cgctttatta acacatattt aaagaataac gatcatcctt acattttaag 467220
aatccctcga ggcgatattg aagatatgaa tgtaggtgat gagcttttaa ctattggtaa 467280
atggcaagtt gtaaatcgaa aagattacga tgtaacaatt atttgttatg gtcaaaacgt 467340
taacttgatt cgtgaatttt ttaaagataa agagataaaa gttagaatta ttgatgcttt 467400
atttattaaa cctatggatg aagatatgtt aaatgaaatt attgatgaaa aaccgttgat 467460
tgtttatgaa acagaattaa aaactggttc tttagctagt aatattgctt attattatag 467520
ccaaaataat attttaaaac ggattcatag ttttggagta gatgaccact attctgttca 467580
aggaacagtt gcacaaattt tacaagatga gggtttagat atggatactt tttatcaaaa 467640
agttaaggag atactaaatg aagaaggaaa gaattgatgt tttattagtc gaacagggct 467700
tttttgattc tcgtgaaaaa gctaaacgcg cgattatggc cgggattgtt catgatgatt 467760
atgatattat tgataaaccg ggaacaaaaa ttccaataga ttcaaatctt catgttaaag 467820
gaaacataat gccatatgtg tcacgtggtg gcttaaaact ggaacgtgcc ttaaaggagt 467880
ttgaattaga tataacggat agaataatgg tcgatatcgg cagttcaaca ggtgggttta 467940
ccgattgtgc tttacagaat ggtgtaaaac tagtttatgc aattgatgtt ggaaccaatc 468000
aattagtttg gaaattacgc aatgatccac gtgttattgt aaaagaacaa acaaatttta 468060
gatatgcaac aagtgaactg tttgaacatg gaattcctac ttttgcttca attgatgtat 468120
cttttatttc tttgaagtat atttttgatg cattaaaaaa tattttacat agtggtaatc 468180
aagttgtagc actaatcaaa ccgcagtttg aagctggacg tgaagaagtt gggaaaaagg 468240
gaatagtcaa agaaccatct gtccatcaaa aagtaattca acatgttatt gaatatgcaa 468300
atcatgatgg ctttgtttta gaaaagttaa cttattcgcc aataactggt ggtgaaggga 468360
atatcgagtt tctagggctt tttgttaaag atggtaataa tgttgccatt gacatagaaa 468420
gagttgtaga aacagcacat aattgtttta aagggtaggt gagataatgt tagagagtat 468480
atatattgaa aattttgcta ttatcgaccg tcttgaagtc gattttcata atcatatgac 468540
tgttcttacg ggagaaactg gggcaggaaa atcaattatt attgatgcga ttggtcaatt 468600
aatgggaaat cgtagtcaat caagttttat taaagctgat tgtgatgaat gttttattga 468660
gggtgttttt acaattggtg ctaagtcacc agtcttaaat aaattaaaag aatatcgtat 468720
tgattatgaa gataaattag ttgtttcaaa atcttttaat cgtgataata aatcgattat 468780
taaaattaat tatcgtaatg tttcaaaaat ggtattacaa tcaatcatgg ctgatttaat 468840
tgatattcat tcacaatttg aaacccatag tctttttgat gctgaaaatc atttaattat 468900
tttagatgag ttcattaatc agcctttaaa aaaattattt cagacatact cactagcata 468960
tcgtacttat agagaaataa atcgtgacta tcaaaaagca ttaaacgaag agctgagtga 469020
tgagcaatta gaattttatc aagctcaatt agctgaaatt aatagtcttg atcttgaaga 469080
attagatgaa gatgagttag aacgtgaaaa aaaactgctt caaagttatg agaaaacaaa 469140
tgagcaaatt tctaaatatc gacaatatat gaatggtgat cgtggtgctc tagcaacatt 469200
aagcaatgca ttaagcgaat tagaagaatt aaacgataat cctcaatatc aaaatacgta 469260
tgaaaggatg tatgacctat attataattt aattgatctt gatgatgaaa taatcaatga 469320
atttaatagt actaattttg atgaatatcg tttaaatgaa attcaagaag tcttttttaa 469380
attaaatcgt ttaaaaagaa agtacggaca atcaattgag gcgattaaag aagctaaaga 469440
agatttagaa atgaaagttg cagcttttaa caatcgggaa acatatttga atgatttaaa 469500
aaaacaattg gatattgctt atcaagagac caaatcaata gctgagcaaa ttactagatt 469560
aaggcaatca aaagctaaag aatttactga attagttaca aaagaattaa aatctttata 469620
tttagataaa gttgttttta aggttgattt taaattagtt gattttcaaa aaaatggaca 469680
agataatgta gaattcttaa tttctacaaa tgctggacaa acattaaaac cgttgaataa 469740
agtagcttca ggtggagaaa tgtccagaat tatgttggca atcaagatat tgtccttatc 469800
ttcgagctct gtggaaacaa ttatttttga tgaagctgat actggcgtta gtggtaaagt 469860
ggctgaaagt attggagcaa agatgaaata tattagcaag cagcatcaag tattgtgcat 469920
tactcattta gcacaagttg ccgcttttgc taaaaatcat tatttgatcc aaaaatcaag 469980
taatgacaat tatacaaatg taaagattaa agaattatct tatgatcaaa gtattaatga 470040
aattgctaaa ttgatttctg gaaaagaagt atctcaggaa tcaataaatc atgcaaaaaa 470100
attaaaaata agtagtgaat aattaaaagc atagaaacca aactatgatg taacgaatgt 470160
tacaaggagg tttctatgct ttttaaaaag ctaatccttt cctttatctt agctttagcc 470220
attattaatc caattgcaat atatgctatt tctctagtac ctggtggaga ttccattgga 470280
atcgagctag attatcaagg tgtggttatt acaggaggat ataagatcaa agtcggtaat 470340
gaaagctacg atccactagc aaaagatttt aaagttggag atattattgt cgcaattaac 470400
aatcaaaagg taacaagtat tgaagaatta agcaatgtta ttaaagaagg cgatatagct 470460
aatcccagat atgatttaac cattaaaaga ggtaaagaaa ccctccacca cgacctccag 470520
gtcgtttatg aaaatcagca attttctacg ggattatatg tcaaagatgc aattagcggg 470580
gttggaacac ttacatttta taacccggca actagtactt ttggagcttt aggacatgca 470640
atgagtgact ctaaacttga cagcgaagag cttattcaaa atggtaatat ttttgaaagt 470700
acagtaacta gtattaaaaa agcaacaacg caatcttcag gaaataaaat tgcagacatt 470760
tccaatattg aaataggtag tataaacagc catagtcaat ttggtattta tggaacttat 470820
aattatgata tttcaaaacg agaaatgatg gaaactgcat ctattgaaga aactaaatta 470880
ggaaaagcct actttttaac tgttttagat ggtgataaaa tccagaagtg tgaaattgaa 470940
atcactaaat tgaatgacca ggattctata aaagaaaagg gaattgaatt tactgtgaca 471000
gatcaagaag taattaataa agctaatgga attgtacaag gaatgagtgg atcaccgatt 471060
attcaaaata acaaaatagt tgggtgtgtg actcatgtat caggtaataa tccaattatt 471120
ggctatggtc tatatataga ttggatgctt gagatggata aataaggata aaaaggtgct 471180
caaattgagc acctttttat ttcaatttgg tgagattttt agtataatta tacagttaag 471240
ggggaaacat gatgaattta ttaacgataa aaagtgcatt taaagaaagt atccccgtta 471300
tgatgggata tttagtctta ggatttgctt ttggaatgtt gcttgtttct aaaggatttc 471360
caatttatta tgcatttatt atgagctgtt ttatatatgc gggaagtatg cagtttgtaa 471420
caatttcttt attagctggt caagcttctt ttattagttc atttattatg acactgatgg 471480
ttaatgcaag gcatttagtt tatggattat caatgttaaa aaaatttaat tttttaggga 471540
aattaaaacc ttatatgatt ttttcattaa cggatgaaac attttcttta cttgtgaaaa 471600
atgattttaa aagtaagaat gaggtttttt taataagttt tttagatcaa tgctattgga 471660
tcattggttc tttggtgggg gcaacaattg gaaataatgt atcttttaat actcaaggtt 471720
tagaattttc aatgacagca ttgtttatag ttattgtaat taatcaaatt aaaaataatt 471780
ctaatcattt agcgacattg attggttttt ttgtcagcat aatttgtttg attatttttg 471840
gtagtgataa ctttgttatt ttttctatga ttttaatcat gataatatta attttagtta 471900
aaccgaggtt aaaaaatgaa taatgatgtc ttgataataa tagcagtagc tttaggaaca 471960
atcttaacaa gggtcttacc atttctgata tttaatgatg ctgaaaattt accaccggca 472020
attagttatt tatctaaagt gttgccatat tcaattatgg caatgttagt tgtatattgt 472080
ttaagggata caacttttat ttccggaaat catggttttc cagaaataat tgccgtttca 472140
attaccatta taattcattt attaaaggaa aatactttat tatcgatttt agtaggcaca 472200
attacatata tgatttgcat tcaagtgatt tttgcataaa ggaggtatag taatgcaagt 472260
tgttttccac attgatctta atgcatttta cgcaagtgca gaaatatcac gtaatcctga 472320
cttaaaagga aaaccaatag ttatatctgg taaatcacga cgaagtatta ttaccacagc 472380
ttcttatgaa gcccgtgaat ttggcattca ctctgcaatg ccactatttc aagcattaga 472440
attgtgcaaa gatttaattg ttttacctgc cgattttgaa ttatatcatc gtttatctaa 472500
tgattttttt tcaatagtag cttcttatag cgaaatttta gaggttgcta gtattgatga 472560
atgctatgta gatgtaacta aaataattat agataaacag attcatccaa tattacttgc 472620
taaagaaatt caaaaaaata tatatgaaca tttaagttta cgctgttcta ttggaatcgc 472680
accgaataaa tttttagcaa aaatggcaag cgatatgaaa aaaccaatgg gaattactat 472740
acttacaagg tctaatttaa aagaaataat gtggccatta gatattaagg atatgtttgg 472800
aattggtaaa aaaactcagc caaagcttaa agcagtagga attaatacaa ttggtgatat 472860
tgcaaattat gataactata ataaactaag acaaattatt ggcaaaaatg cgctactatt 472920
gtatcgtaaa gccaatggaa ttgataatag cgctgttgat gctaaacaaa atgaattaaa 472980
gtctgtagga aactcaacta ctttaccata tgatacaaat gatgaggaaa tactaaggga 473040
tacattaaag agtttagctc gccaagtttc agcgcgagct aataagcgca acttaatttc 473100
aaattcaatc tcgattacta taaaatatac tcgctttgaa agtgttacta gacaaactac 473160
tgtcaattca tttattaatg attatgaaac catattatct actgcaaaaa tgttatttga 473220
tgctaattat agcggtcgac ctgtgcgtct tttaggcatc agtttaaata atacaatcaa 473280
taagaagaac tacaaagaac aacttaatat ttttgaaatg gcgcaagagg atgaaaccaa 473340
tgatgattct cttgaacagt tactaaatgc tatcaataat aaatttgata agaagctggt 473400
gactaaagct tcatcatttg caaaaaagac tccccaaaag aaatatttaa aataaaagaa 473460
taaaataatg atttgctcat aagttgtata aacggaggat aacttatgag cattttaaat 473520
aaagttttta gaaatgaaaa agttttaatt aatatatttt ctgcaatatt atttgttttt 473580
ggtatcttat ttggcattat ttattatttt tatggtaatg aagccctatt aaatttatgt 473640
aaatatatct tttttttcaa agataatgag acaaccaata attataatct atatattaca 473700
attactagtt tctacatatt tttatctcta ataatttcaa ctagtttttt aggaacaatt 473760
tttaatagtt ttgttatttt tacaaaagga atgcaattat cgattgcaag tattttttat 473820
tttactttaa atacgtttga tgcatctatg ctttttttag gtttttttcc acaattaatt 473880
attgaattag cattaactta tattatttct ataatttcta ttagattatc aataaattgt 473940
tttacaattt catttttgac aacagaagta tttaatagtc gaaaaataat taattatatc 474000
ttagattacg taataattat cttaataata gtcacattat caatggcatt taaggtttat 474060
gcactttagt tagcaaatcg ttagtatggt taaatttaaa cgtgatataa ttattaagtg 474120
aaggtgaggt gaaagtaagt gtagtacttg ctaaatttat gttaattaaa gatgccttaa 474180
gtgaatataa gcaatatttg attgttgaaa aaggtttgag taagaatact atttattctt 474240
atctacgaga tttgattgct ttttctaatt ttatcggtga ggaatatgaa attaatcaaa 474300
ttgaaaatat taataaagaa catattcatc tttatttaaa ggagttatcg aaaacaaact 474360
gtactaattc aatttctcgt aaacttgttt ctttacgaat gttatatatt tttttagtga 474420
aagaaaatat tgtgaaagaa aatctcatga gtagttttac cttaccgaaa agagataaaa 474480
aattacctat tgttttgtct caagaagaaa tgatagagat acttgatggg atcattgttt 474540
gtgatgcaat tagttcgaga aatagatgta tggttgaatt gctatatgca acgggtatgc 474600
gtatttcaga attgttgaat cttactttga aagatttaaa tattaaaatg ggatttatca 474660
aagttattgg aaaaggaaac aaagagagaa tgattccaat cggttcatat gttggagaga 474720
tattggaaca atacataaat gattatcgag ctgaatttaa tataaaaaat gatagtttat 474780
tattttttaa taagcatggt caaagattaa gtagagaaga attttattct atattacaaa 474840
caattgtaaa ttcaacttct ataactaaaa aagtctcgcc tcatactttt cggcatacgt 474900
ttgcaactca tcttttagaa aatggtgctg atttgcgttc tattcaagaa ttgcttggcc 474960
acagtgatat tagtacaaca actatttata cacatatttc gaatcaaaag attagaagtg 475020
agtatcagca attccaccca cgcataaaaa agcataatga tgggtaaaat aatgtctaga 475080
tatggaaaca atttaatgat atacttatga ttgcgtaaaa agtgacgcaa ggaatggagg 475140
acaagatgaa atacaacaga gtttttttaa ttgtgtgtga ttccttagga attggtaatg 475200
caaaagatgc taatttatat aacgatgaag gatcaaatac tttaaaacat atatgtaatg 475260
cctgcaatgg ccttgattta ccaaatttgg aaggattagg attaggaagt ttgggtaatt 475320
tttctggaat acatcaatta acttcacaat taggatatac tttagcttta aacgagattt 475380
ctaatggtaa agatactatg accggtcatt gggaaatgat ggggcttaaa actgaaaaac 475440
catttattac atttaccgaa accggctttc ctcaagaatt tattgaactt tttgaagaaa 475500
aaactggacg taaatgtgtt ggcaataagg ctgcaagtgg tacagcaatt cttgatgagt 475560
atggtgaaca tcagataaaa acaggtgatt ggatcgtata tacttcagct gattcagttt 475620
ttcaaatagc tgcaaatgaa gagattatcc cgttagaaga attgtataaa gcatgcgaaa 475680
ttgctcgtga aatagccatg gatgagcgtt ggaaagttgg tagagttatt gctcgaccat 475740
atgtaggaaa aagggtaggg aaattcaaac gtactgccaa tcgtcatgat ttggccttag 475800
caccatttgg acggactgtt cttgataatt tgaaagataa acagtttgat gttattggag 475860
ttgggaaaat tccggatatt tttgttgatc aaggaattac taaagcagtt aagacggtaa 475920
gtaatcagga tggaatggaa aaaactgttg aacttgcaaa atcagaattt aaaggattgt 475980
gttttgttaa tcttgtagat tttgatgcag tatacggtca tcggcgtaat cctgagggct 476040
atgggcaagc aattgtagat tttgataagc aattggagga attaatgaaa tatttaaatc 476100
atgatgattt attaatgatc actgctgatc atggtaatga tccaacttat agtggtactg 476160
atcatactcg tgaacaagtt ccattaatta tttattcaaa ggaattattg aagccacgtc 476220
atttacatga tatggaatct tttgctgtaa ttggtgctac aattgcagat aattttggta 476280
tcgaattacc aactattggc caatcaattt tagaattaat taaataggag aatttatgga 476340
agataataca aaacgattga tcgtgatgtc aattttagct tatgcaattg gaacgtttat 476400
ctttgctgca ggattaatga ccaagacagc cgttagcata atattatttt atataattgc 476460
aagcatatta ataatttgcg gtattttagc attatataat aattataaaa aaaatcatca 476520
aattaaatta tacttatact taatagtggt aggaattgtt ttcttgtttt taaatacaac 476580
ggcattaatt aataacttat agtttataaa agcattctaa gattattgga atgcttttaa 476640
ttaggattta tcgatcaatt tatttgtgtt tgtctattaa aaatcaatta taaaatttac 476700
ataatataca ttatgcgaag tagtatatat tcaaaaaaat taaattttat ctttgataag 476760
gttaactaag tcgttagcct tttccacatt taaataatga tcataatagt cagctttaag 476820
aaacatagtt aaatgaggtc tagcaatacc cgtctcttta caaaaagatg taagattaag 476880
atattgtttt ctttcattga taaattcacg acattcgctt ttagataaca taggcaacac 476940
tcctttataa tataagtgtt cgcatatgta tattatgtaa tgtataagta tataattaac 477000
ttacaaatta aatatatcat aaataaaact ttatgtaaat ataattacat aaagttgatt 477060
aaattattta tataatacaa tattgccaat ataatttata taattaaaca tactaatttt 477120
ttttatacat aaatagtcaa cttcattatg aataagcaaa tcataaacaa tagcaaatct 477180
ttcaaaatca acacaataaa tatatttaat agttttttta acaatataac taatacaata 477240
gtattcataa gttctcatat taatcacctc ataaataaat tataataaat ttatttctta 477300
tttactattt ttatataaca aaaatcattc tcatataaac catcttcgtc caaaaagaaa 477360
tctatatcta cctctttatt atatataact ttaggttcac taattaaacc attactacag 477420
taataatatt tactaaatat cctatcttcc atttttgtaa tatacttact aatataacta 477480
gaaattttag aatgactttc caacccttta tctattttaa ccgcagtatt ataaccttta 477540
ttatcttgcc atgaaacaat attatataca tctctatccg ttttactttt tatatttgca 477600
tttaccaatt gcattttatt attactatcc cgtattagcc cgtgccaatg caaagcaccg 477660
tccttatgca gttcgggaac aattatatac ttaataccat gtttcttaga ctgatttttt 477720
aaatactcta gtgttctttt ttttaaatct tccaaattat acctatcttc tactttatcc 477780
ttagaaaatg taagagttat aaaataatcc caatcattga gaatagccat attaaacacc 477840
ttagacttag aacgtctctt agaccttgca atattatatt tcctaatatc ttcataatca 477900
taaagcaaac ccaacttttt aagaaacctg tctaaatcag ttaaaccgtc attgtaaacc 477960
gatatatcat acttaccgtc tttatcctct tctatatagt ccctaatctt gacattattc 478020
ttaaaaagta tttgcttttc aaaagacccg taatctttta caacgtagtt agtatagacg 478080
ttacattctt tatcatgcaa tccacttaaa tctataacaa tcacctacaa tctagggggt 478140
accccgatag tgtccctata tcaagtaagg gacacgcctt taaaccattt ttttcactcg 478200
ccgttaggcg tcctaaagtg tatatataca ctttagggtt gcaacagtgt ttatgcctta 478260
cacttccaca acaacaaaag tgcataaccg ctgcgctttt ataacttttg cggttgtgtc 478320
gttgtcggct acgtattata atttagaacc tactcggctc gctttgctcg tggaccctcg 478380
ttggatctaa attaaaatac tatgttttta atttttcacc attatcccaa ccataagaat 478440
tatatagaga acgtatataa tcactttgaa tgaacttaat tttcttgaac gggtgtatct 478500
tcattttttt attaatatcg acttcctcat aaagtgcttt ataatcatag tcccgatacc 478560
accgaacttt tgtatatcgt ccaaatatag tcttgcacac tccatattcg atagttaatc 478620
tacgaatagt cttatgtact aattcgtggt cttgactagc ccaatagaac attttgccat 478680
tacctttgcg gtttaaggac aatgcttgtc ttatctcttt aggaaatacc ttatcagtag 478740
cggggaattc attttgaact tcgtcccaca taaatactat aggtttatcg tactgcacac 478800
ccgtttgtct aacatcatta aactcaaaat cttggattga caaaccgaaa ttagtacaaa 478860
tataaatatc atttccatgt ttattcctta aatttaaagc aattttagtc attgccatag 478920
tttttccaca accatacata cccgttaaac aacgtacacc gtacatgtgc aattttttac 478980
catatttttt aaatctatat aaatcaatta atttccattt tattaaatct aaaagtatta 479040
tcttaaattc aaattccttt atcttttgtt tagtttcatt tttcataaaa aaccccttta 479100
tataaatact gttgttaata cactgcgccg tagaacgttg cgcagtgtat taattaacac 479160
caggtatctt tatatatacc cattctataa ttgcccaaag tatatcaatg ctagcccaca 479220
acactacact agcgaatacc attgcaaacg gcgaactgcc aaagaaatat ataccatact 479280
gcaacaaatc ataaaataca cttgtaatag agccttgctc actattcatc ttaggtaaaa 479340
gaccaataag aaaatttgca aagccaaaga aaacttttag caccaattca gttatcattt 479400
ttcgctacct accttattat tagcattttg accactatgt ccgtctccct ctattggttt 479460
agattttcta attaaaaaca aaacgtgaga ataatggtac caacacaaga atatagcaac 479520
taaccccgta cctaatgcac gagtataagg ctgagcataa gaaaggaaag ataagtctat 479580
agactgtcta tgtccaaaga ttgtaaaaac tataggagta aatatatcgc ccctaacctc 479640
tttagtttta gtaagactat ctaatatact taaatctata ccaattttat tactaagagt 479700
atcttgtata gttttaaaat tactatctag aaaattatca ctaggaacaa atagaccttt 479760
taataaattt cctaacaact ctagaaaata gctaagaact tcccctaaaa catcaaagaa 479820
agtacctata aaatcaaata aaggctgaaa aataagtttg attaagttac caatagctga 479880
agttaaagaa gaaacaagac caccaagaaa atctaaaact ttacctactg cacccgttac 479940
tttatcaact gaaccaacaa caaaatcaaa gccaccgctt attaaaccgc caatcgtatc 480000
gaacgccgaa ccaagaaaat cagtaagccc gccgaaaata tcgccaaacc aaccggtaat 480060
atcttcccac catccgctac tatcttcccc ggaatctccg ccactacctc cggacggata 480120
accggttcca ctaatagcgc cgcatgaaaa cccatagaat taatcctatc taacaacgta 480180
gtatcattgg tttcatagcg aaatgaagca ttagaattat tgacctctgc tacaccaaca 480240
ttagcagttg tagcgtcgaa ccaaccatca gcagaattat aaatagcatc accaacaaat 480300
gaaatattaa gaacaggttt accaccgtaa gaaccttcct taaaagtggc gctattataa 480360
taataaaatt ctatttcctt atcatttttt aataaaataa aacaatactt gtactcttta 480420
tcttgaaccg tataagcatt aacactagaa ccagtaataa atatagaact aaatacaata 480480
cctaaagtaa gaagtatttt ttcaattttg tgattttcct taaatttaag aatatgatca 480540
cgcgcatttt ttataatttt cataaatttt tatcctttct ataaaattaa agggctagga 480600
ataaatatcc taacccaata taagaagtta atcttataag aatttataaa caattcttgg 480660
gataagacta acgccaatca taattcccat gattgtaatg ccgacaggta ataaaatacc 480720
taaatccgaa ttaatactgt cagtaatcgg ctttaacatt tcagcagtta acatttttga 480780
tttcctcctt atataaaatt tcttaagaat ttataaaaca taactaagaa gaatacagct 480840
agagcaacaa caagacccaa gtaaacaaca ttattattta attgtgtatt gtattgaagt 480900
gtttccaagt tatggtttat actttgtaac tcaaccaata attggtcttg attgtctaac 480960
tgttggttag acgtttcgtt ttgcatttgg gcttgttcat cttttgtata aaaatactga 481020
ctaagcagtt gattaagtac ctcaatatca atgcttgatg tttcatcaac tgaagtgccc 481080
tcttgaatat cttcatccat agtcacctgt tacctttcag caatccataa attgtaccaa 481140
taactaaagc acctacaaaa agccatatca tactcatatt attgacctcg tttaatgaaa 481200
ccacatacat tgacataatt tccattttta cgataattga aatcgccctc taaacctaac 481260
atagaaacag tttttaaacc ttcgcacatc tgttcataag caactggtgt aagccattca 481320
taaccgcaca aactgccttc aacattatcc ttaccatgct ccatatcgtt ataatggact 481380
tttacacccg taacatgttt accttgttta ttttcataat ctaaactttc aattcctaca 481440
atcttaatca ttttcttttt cctcttttct ttatttttca tttaattaaa taagaatact 481500
ttatgtaaga ataattacgt atgtatacat tatgcgaagt tatatatgtt atatctactt 481560
tactaattat aagaggtaag gagtttttaa tattccttac ctttcttgat tttatccatt 481620
tcaaatgaat catataaatt tgttacatat tcaccattga aacaagctaa acataaacta 481680
catttatgtt tttctttatt aaaatggata gatttatcaa ttccttcttc agtaataaag 481740
gcaagtgaat cagcttcaat ataattgcat aattcattaa cattcaaacg attagaaatt 481800
aattcgtcca tggttgacat atcaacacca taaaaacaag gatatttgat tgctggtgaa 481860
gcaattctta catgcacttc tctagcacca gcttctttta acaatcgtac aattctttta 481920
gaggtagttc cacgtacaat tgaatcatca atcataacaa cacgttttcc tttaacaatt 481980
gaagaaactg cagataattt cattcgaacc ccctgctctc tcatttcttg agtaggttga 482040
ataaaagtac gacctacata tttattctta atcagaccca tttcataagg aatattagct 482100
gcttctgcat atccgattgc agcagaaata gaagaatcag gaacaccaat aactaaatca 482160
gcttctactg gtgcttcttt aaataattgt ttaccagcaa gttttctagt tgtatgaaca 482220
tttattccat ctaaattact atctggtcgt gaaaaataaa tatattccat tgcacatatt 482280
ttatcagtaa catcatttgt ataaagcttt gatttgattt gaccgtcttt gactctaacg 482340
atttcaccag gttctaaatc acgaacaaat tttgcaccaa caacttcaaa tgcacacgtt 482400
tctgatgaaa atacatatgc cccattaggc aattgaccaa tagaaacagg tcgcaaacca 482460
tacttatctc ttgctacata caaagcattc tcaatcaaaa tcaaaaaggc aaatgcacca 482520
tcaagtttgt ttaaggaatt acaaatacga tcaatcatat gaccttcttc acgcataatt 482580
aaatgaccta aaatctcagt atctgaagaa ctagaaaaaa tgcttccttt tttttctaag 482640
tccgccttta agacattggc attaacaata tttccattgt gtgcaattcc taaagatcca 482700
tttaaggttc taaataataa tggctgaaca ttagcaattc caccaccacc agctgttgaa 482760
taacgaacat gaccaatagc atgatcacct ttcattttgc taattttatc ttgatcaaat 482820
acttcagtaa ctagcccttc acccttttga attgacaaag cttctttatt ttttacaaca 482880
ataccagcag cttcttgccc ccggtgttgt aaactatgta atccatagta gcacattgct 482940
gcagcatttt catatccaca aactgcaaat actccacatt cctcatgtaa ttctcgatct 483000
tttgaaaaca ttaactaacc tcctcttaaa tacttttaca ttttataatg cagagatagg 483060
ttagtcaata aaaaataggt attataggca ctcatttata taaaatttat tatcttgaca 483120
actatttttt aaaaaattgg tcaacattgt acatatatac gtacaatcac caattatttc 483180
attgtttaaa tcactttcaa taatcagttc tttgtttgtt tttgataaga aacaaacgat 483240
tttatttaga ctttcataat tagtatagat tatttcactg acctcaattt tagaagcact 483300
ttcatgataa attgcatatc caattatttt agcattatca taaaataatt ttatttgatc 483360
gttataagca cggcaacgtg caattaagta attttggtaa tagtcgatat ctcttttacg 483420
ataaccatta aaatcttttg tgaaatcatt atataattta agtgaattta caaaatccag 483480
atcttcaata actgttaaat cataatcatt ttgatatgat tttttgtcaa catttgtaat 483540
tttatgataa taatctttat taaatccaaa attataataa atttctggca tgtaagcttg 483600
aagtaaaatc ttttgaccag catattttgg caagttaagc acatagttca ttaacttttt 483660
catcattcct tgcttttgat aattcttatt agtagcaaca ccaagaataa agtatgcctt 483720
tatctcctga ttatccagaa caatggtata tgggactatt tgcatcattg aaacaaggaa 483780
gttgttattt tttaatagat atgtattttc tttgctgtaa catttcataa aataaaagtt 483840
agttgtttgc ttgtcttcat cttcaaaact atcacgccat aggtcaataa ttgaatgcag 483900
atcattatct gctgccggca taattgatag gttactagga acaatattat atttcttaac 483960
cattttaact gggtgcagca tttgtttagc acggcgtagt gattctaatc ccatatcttc 484020
ctcacggtta acaaattcat aaccctcaaa atttcgttct aggaagaatt taccaatcgc 484080
cacatataat cctctaatat ctttattagc cttctctacg tgaatttgaa cggtactgtg 484140
tttaagtggg gaaccaataa taaatgcttc taactgtccg ttaatgtaaa tacagccagt 484200
ttttatttcc aattcatgac gatgtactaa caagtagaca atcccgatat actcagaaat 484260
aacactctct tctattcgat gagaaaaatc ccattttttg agacactgta aaacattatc 484320
aacatcttca tcttcaattt ctttataaat ataattcgga ttttctttaa caaacgcatt 484380
aaagtgattt cttctctttt gcattttttt tcctgccaaa gattctagag atttttttgt 484440
atagacataa tcatcaaaat cttcattatg caaatacaaa aacttatctc catatctttc 484500
tttaattaaa ctcatagatt cttcaacagc taaatcgatt ctaaaaagaa agttatgctc 484560
tttagcatag ttttgcatat attcgattgc ttcatagtag tactctggtt tgcaaaaagg 484620
cattgcaaaa aacttttcgt ctaaatatgt gtgtaacata accatgaaat tatcttttat 484680
ttcataatat atttcatatt catgatccca catcatcatt gtgacaaaat tagaattata 484740
gccctcataa tttgcatcgt ctaaatattt ttttattttg tgataatcgt ttaataataa 484800
ttttcgcata ttactcctat tgttttattt acctagcatt gcattaataa attgtttggc 484860
agttcttcct gaaaatccac cgtgacgaat ttcccaagtt aatgcttttt gatgcaattc 484920
gttacgctcc atcattaaac catattgttc ggctaaacca tcaacaatat ctaaataatt 484980
ttgacgatct ggatgcataa ataaaatttt aacaccaaat cttgaactta atgatgtttt 485040
ttcttgttta gcatcattta cattaacctc atcctgatct tgacgatcac cccatgtttg 485100
ttttactaaa tgacggcgat tacttgttgc ataaatcaaa atattatcag gtttcttttc 485160
taacccgcct tcaatgactg cttttaagta tttatactca atttcaaatt cctcaaacga 485220
taaatcatcc atgaataata caaatttata attacgtgac tgtaattctt gaataatact 485280
aggaagattt ataaactgat gtttataaac ttctatcatt cttagaccat ctttataata 485340
ttcgtttaat aaagctttaa tactacttga tttaccagtt ccactatcac cgtataataa 485400
aacattgttt gctttttttc ctgctaaaaa tgcctcggta ttttgggtaa gtttttcttt 485460
ttggctttca taaccaatca actgatctag tcgcccatta cctatatgta ttataggact 485520
aatttgctca ttttcataac gaaatgcttt atttaatcca aattttccaa ctccatacgt 485580
taaaaagaag ttttctaata cattataaaa tgattcaaca tcattacagg cagttaaatt 485640
gtcctgtaat gtttttgaaa cttcgaatag ttcaatatta atgacaggct ttgaaggtgt 485700
gaatcctgtt atcaaatttt gttgtgctaa tggcaagaca ctaaaatccg tattaaacat 485760
tttgaaaata atcttaaaat cattcataac aatttctttt aaattagcag ctattgtttt 485820
ttttctttct aatgctagag taaacgaatt ttcattatta attaacaaat aagttaataa 485880
actattaaat agattatcgt acaagttgta tttttcagct aatttaatta acaatgaaac 485940
aaatttactg ctattttcaa gtttcccatc tactacttca gtatataatg caaaacactc 486000
agcaatatct ttatttttat acaatggatt aaaaactatt aaatcattca ttttacattt 486060
tcctttcaat ataatgaaaa agacgagtta acgtctttta atttttaaaa ctatgaattg 486120
gtgcaggaat tctaccacca cgattaataa attcagcaca tccaaattgg tttactggca 486180
ttacaggtgc ataacccaat agtcccccaa attctactac ttcaccaaca tttttaccga 486240
ttacaggaat aattctaaca gctgtggttt tttgattgat cataccaatt gccatttcat 486300
cggcaatgat tccagataaa gtagtgactg gagtatctcc aggaatcgca atcatatcaa 486360
gtccaactga acatacacat gtcatagctt ctaatttttc aagtgttaat gcgccacggt 486420
ttacagcatc aatcatacct tgatcttcac tgactggaat aaatgctcca cttaatccac 486480
caacatatga agaagccata acgccacctt tttaacttga tcattcaaga ttgctaatgc 486540
agctgttgtt cctggagcac caacactatc caagcccatt ccttctaaac aatcggcgat 486600
actatcaccg attgctggag ttggagctaa tgataaatcg atgattccaa aaggaatccc 486660
caatttttcc gacgcttcta aagcaactaa ttgacctacg cgagtaattt taaacgcagt 486720
tttcttgata atttcacata actctccaaa atcttttcct ttggcattgg caatagcatt 486780
tttaacaaca cccgggccac taactccaac attgataatt gcgtctgctt cactaacccc 486840
atggaaagcc ccagccataa atggattatc gtcaggtgca ttgcataaaa caactaactt 486900
agcacaacca atagaatcat tttccttagt taaatctgca gtttcatgaa tgatttcccc 486960
cattaatttt actgcatcca tattaatacc agttttagtt gatccaacat ttaccgaact 487020
acaaacatta ctagtaactt tcattgcttc aggaattgaa cgaattaata attcttccgc 487080
ctttgtcatt cctttggaaa caattgctgt ataaccaccg atgaaattaa ctccagtttc 487140
atgagcacat ttatccaatg ttttagcaat tttaacaaag tccgctgttg atttgcaagc 487200
attagagcca acaaatccaa ttggtgttac tgaaattctt ttattgacaa taggaattcc 487260
atatttcatt tcgatttgtt tacccgtaga gactagattc ttagctacgg tagtaatttt 487320
tttataaata ttttcacata aaacatcaat atcatgatcc atacagtcta ataaactgat 487380
ccctaatgta attgttctca catcaagatt ttcttgctca atcattttat ttgtttctgc 487440
tacttcaaat aaattaatca ttccgattct ccttaaatac gatgcatttt attaaaaatg 487500
ttttcatgtt gtaatttaat atttactccg atttcttcac ctaatttatc taaatcttca 487560
cagatagttc caaattcttc ggtaattgaa cttagttcta caatcatcat catgttaaaa 487620
taaccttgaa tgatagtttg agaaatatcc aagatattaa cttgtttttc cgctaaaaaa 487680
ctacaaacct tagcaataat tcctacttga tcttttccta ctactgtaat aatccccttt 487740
tgcatactat tacctacctc ctaattattt aggatattat atcatagttg tatacaatat 487800
aaaaccccta tttcttgaaa tttcgtcaaa ataaaaacgg ataaatttta tccgttttta 487860
tttaatcgta aggaattatc ttcccattaa ttttttagca aattcgtaaa cagctttacc 487920
attcatcatt ccgtaatctt tcatttcaat tacatcataa ggaatatctt ttccagtatc 487980
tgcaataatt ttttcaactt ctttttttgc atatctaact tgtgggccaa gtaatacaca 488040
atctacagta tcaataattt tttcaccttc tgtcaaaggt aaagcaaaga tttctacttc 488100
ttctccagct tcttttgctg ctacttccat ttttgttact aataaactag tagacatacc 488160
tgcagcacat actaacataa ttcttgttgc cataactaac tctctccttt attgttaaat 488220
ttcatataaa aagggcatca caaaaaacgc ccgttttatc ttttgttatt tcagtttaag 488280
ctttttgatt acccaatcat tttcattgca gcttcaaata cagctttacc gttcatagtt 488340
ccataatctc tcatatcgat tacatcaaca gggatagctc ctgctttacg tccagcagcc 488400
aatttttcaa tagcagcttt ttggaatcta acttgtgggc caagtaaaat acaatctact 488460
tcttctaata ctcttggtgc atcagagaat ggtaatgcaa aaattttaca ttcaacacct 488520
gcatctttag cagcaccttc catttttgtt actagtaagc tagtagacat acctgctgaa 488580
cacactaata aaatagtttt cataataata tacactcctt tttttttacc taaattaatt 488640
ttacaccgaa tggcttagaa tgtaaacact ttcttggctg aaatgcttta tttttttaca 488700
attaaaaatg aattttttag taaaaaataa cttctactct tagttaataa atcttaccat 488760
tttaaaattt tccttgttag aatcatcaat ttttaaagct ctttaacacc gtttttttga 488820
agtggaatta taaaaaaaga atctaaaaat tttaattttt cttttataaa atatttcaaa 488880
taaatctttt tttatagtat aacagacgct attcttctgt acttgtctag accattggtg 488940
tcaaagaata attatcttta tttttatcct ttttcaaata tgttatgata gataaagaag 489000
gaagtgattt tacatgcagg tattagtaat tagtgatact catttacaaa atgaattatt 489060
tcaaaaaatt aatcaaacat atcctaagat ggattattat ttacattgtg gagattcatc 489120
cttaaaaaaa gatgatttct tgttaaacaa atattatact gtaaaaggta atcatgatga 489180
tgaagatttt ccagtcaata ttattttaga aattggaaaa tatcgctgtt taattactca 489240
tggaaatgct tacgatatat actacggaaa tgataaaata aagcaatata tgattgctaa 489300
taatattgat atctgttttc acggacatac tcatgttcct gcatataccc aaattggtaa 489360
ccgttatatt attaatccag gcagtgtgat gatcaatcga ggttcatatg gtttcggaac 489420
ctttgcaatc gtggaaatcg gtgatactat aaaagtaaat tattataata gtgaaacttt 489480
tgaagaatgc tcaaaaatgg ttctagacga tggaaaaatc gttttagaag aatttaagca 489540
aatactaaaa tagaagtgag atttaaaatt tctcacttct atttttttct tcatttcgct 489600
tacgcttata ttcaatcata aacattactt cttttaaatc ttcatccggt aactctgtta 489660
acaaccgtgc gatattagca atattatagt agtcgtattt tttaccactc attatttctt 489720
ctacacttcg tccatacaag ttagaaaata ttcttaattc ccctactgta atatccctct 489780
taccattttc aatatctgaa atggctgaat gtggtacttt taaataagca gcaacatcct 489840
tttgtgtcag gtgtttgaaa ttccgataag attttaatcg tgccgctaaa tctttatcaa 489900
tcatcattat acctccgata aatagatttt agcattttcc ttatttttct tcaataagat 489960
tttgtatatt tataatttat ttcgacaaat aataattttt atttatataa ttagataatt 490020
agtcataaaa atatccatta gttagttttg tttttaaact aatttgtcga ggtttagcaa 490080
acataatatt atttttgaaa tccctaaata cagctttggt gatttctggt gcttcattac 490140
taaatgaaag caaaataaaa tcaacttcta gtttttctaa atgatcaatg taaagacagt 490200
gactattgaa tattaagtta ttacagtctt gatctgggaa aatatcaaat tgttcacctt 490260
tacgatcaat taaagtaaac tttccttgtt tacaaagatt acatttgatt tttttacaat 490320
taaaataatg atcacttatt aagcagtgtt ttagatgcat attgattgtt ttgccataca 490380
ctgtcattat aatattttgt ttaatattat ttaaatgatt aacttgtttt ctactcatct 490440
cgagagaaag aatagcatca tgattattaa aataattcaa agcatagcta ttataaaggt 490500
tgaaagtact atctaaaata cattttttat ctttaaaaat ttgtaatgct ccatagtcac 490560
ctactaaaat actatttatc ttattgtatg agacactatt tttaaacttg attaaaatat 490620
cctgattatt caaaaagctt gtaaatggga ttatttcttt atttacagaa tgcgctaaac 490680
ttatagcttc atcaagttct tcgttgatag gaaaataata tgcatccact tcctctgtta 490740
acaatgcttt taattgtgcc aaattataaa tttttaccac aatcccttta atttgtttat 490800
taatatgatt atgtttagtt ttaatcattg gttttttaac tttttttatc tttactatca 490860
tattagaaag ttcatctatt gcttgacgac gcatttcatt aatttcttta atactaaaaa 490920
aaccattatc aggaaagtca atagtaatat catttgcctt aaatactgta tttcctaatt 490980
ttcctaattg ttgtctgatt ctttgaggat ctaatggcaa tttagctgct gattcaatta 491040
gaagattaga aactttttca acttttaaat ctttatagtt gatggttaat cgtgctggtt 491100
cgttgatttg acctgaaaat gccatagtta ctgtattttt aatattttca tttttataac 491160
ttgctaaagc ttcattgatt agatctatat caataacctt atatactgtt tcattctttt 491220
ttactggggt attcaattcg atttcaacaa tatcaccagc attgccttga ttaatcaaat 491280
tattaaataa atataacttt gtaatagttc gagtaaaccc aacactcttg aaattaatcc 491340
gatctccttg tttcaactta tcttgtaatt gaatttttac aatttttcga tgtttatcat 491400
aatctatcac tgtaccaact tcaattcctc ggtttccagg ataatcttta gccacaaaat 491460
tttgatcttt taaaatatat ccaccagtga atccacggtt gaacatttgc ttcatttttt 491520
ttatacgctg ctcaaatgca ttaactgtcg tattttttaa atatgcatct attgcttcac 491580
ggtattgttt aacgattgta gcaacatact caggtcgttt catccgtcct tctattttaa 491640
atgatgtaac accagcatca attaattgcc caatattctc aaaggtacat aaatctttag 491700
gtgataataa atagcttgga attttatcta aattcatact atctttttgc aatttataag 491760
cgagccgaca aggctgtcca caagctcctt tgtttccact tcttttagca atcatactcg 491820
acattaaaca ctgtcccgaa tatgacatac atagagcacc atgaacaaac acctcaatat 491880
ctagaattgt gttttgacaa atatcagcta tttcatcaag tgtattttcg cgcgctaaaa 491940
caacacgatc aacaccagca tcttcaaaat atttaactgc tgacaaatta taaatactag 492000
tctgtgttga catatgaatt tcaaaatctg gaaagtattg tttaacaaaa ctcatcagtc 492060
cgatatcttg aataattaaa gcatcaactt ttattgtttg taaaaacaaa agataatctt 492120
gtagtttttc aaactgatta tcttcatata aagtatttac agttacataa attttaacgt 492180
tgcgtaaatg gccatatgca actgcagctt gtaattcctc gcgattaaag tttgttgcaa 492240
aagctctggc actaaattca tttcctccta aataaattgc atttgcacca ttttgaaccg 492300
ctgctactaa agcttcataa cttccagctg gagcaagtaa ttctatattt tgcatatgta 492360
ttaatgctcc gtttctgcaa ttaatgctat acacatttta gctgacgctt gggatgcttt 492420
ttttaaatat tcatcaaatt ggacagaaga atctccctta ccaaaaacat cacttaaaga 492480
acgtgtaata ataaaactag tcccgaattt atagcatgtt tgagcaattg ctgctgcttc 492540
catttcagta cattttgcat caggaaaatt atttttaatg cgtgttgcta cttccggtgt 492600
agcaacaaat tggtcaccag aaacaattag accaatttcg caatttaaat ttaagtttga 492660
taatattgtt ttagcttgag taattagttg acgatctgct tctattcttg ggggtaaacc 492720
tggaacttca ccaatcactc gattgggaaa tgccgtaata tcaaaatcat gttgacaaac 492780
ttcattagaa ataactatat ccccaacttc ttgagttaaa cacagtccac cagcagaacc 492840
gatatttatg acataatcta ttttatagtt agtcagtaat aaagtagtac aaatagcagc 492900
attaactttt cctactccac cctgtaacaa aacgacttgg cgctctttta tcgttccttg 492960
ataaaatgta caatcaagaa tagagcgtgt ttcagtaatc tccatatatt ctttaattgc 493020
tgccacttct tcttccattg ctccgataat tccaatcatt ctacttacct ccccttcttt 493080
tatgacatat aaaaataatt ctttgtgatt tatcatgata ttcctcaaac tcaccataat 493140
attgtacatc cgtaaaacct gcctgtttca ataagctaag ataaatttca atatcgtaag 493200
tttgctgata atgcatttct tttatatgtt cattattttc cttatcaatt atctcaattt 493260
catgttccac tttaccaaga gcagtctttt ctacatgcca tttaaaatag aaatcatcag 493320
catcttcttc ttcaaaatag ccatctagaa tttcatccat cttataaaga ctatcaacat 493380
caaatataaa ggttccatta tattttagtg attcatatac atttttaaaa gttcttaata 493440
ctttcttttt actcaaaaca taattaattg agtcacaaag gcataaaatc aaatctactg 493500
ctttatcggt tacaaaatca gtcatatcaa ctcgacctaa taaaagatta acatctgctt 493560
ccattgcttt caaacgtgaa acttcaagca tatctttaga aagatcagtt gcataaatct 493620
ctttacctgc tttagctaaa cgaattgcaa tttcaccagt tccacaccca agttcaagca 493680
cgcttttaaa atcagcgtgc tcatttataa acttgaaata atcatcataa aattgttcat 493740
ccattaagct gtcatagtaa taagcaaaat tttcgtatga cattaagcta aatattttga 493800
tacgtcaatt cgtggcatat cagaccataa tttctcaaga ttataactgt ttcgttcgtc 493860
agcatcaaat atatgcacaa cgatatcacc ataatccatc aataaccact tgctattgcg 493920
taacccttca atttttttaa cttcataacc attttcatga cagctgtctt cgacactgtc 493980
acgtaaagca ttcatcaatc tctcgttact tgctgaacaa atcacaaaag tatcaaaaat 494040
aggactagct aactgcatgt caattactac aatgtcctct gctaatttat catctaatgc 494100
ttttataatt acttctaatt tattcattaa tatctccttt tgcatattta ttataaattt 494160
caaaaaaaca ttcatcaatt tttcgccctt tttcatggga aaaatcataa aaatcttgta 494220
aacacccttt aaagccagca actacatctt ttttgcataa tgcaattttt tttgaagaat 494280
cgtaatctcg acttggatcg tatttatcag cttcataaat acacatatca agttttgaca 494340
tatataaaga agcagttgta tgatgcctaa ttgcttgtaa tatttcagga tcatcaacta 494400
aatactcatt ttttgcaaca tattcagata accattgatg ccaaaccgcc tctggtttat 494460
taagataatc tggataattt ttttgcatta ttacaacagc ttcatcatga ggcatttctt 494520
tagcaatatc atgaagcatt cctgctacat atgcttttct accatctaga ttattagcta 494580
atgcaatttc tttagctaaa tgagccatgc tcactgtatg acgatagcgt tttaaagaca 494640
ttttattttt cacaattgtt tctaaataaa taccattatt aacaatatat tttaaaactt 494700
caggatttaa agcatgtaat gcaccattcc ggatattatt actagcgtca tcactggcaa 494760
ccaaatctaa gtgaataaaa ttatatttat ctaaattatc attaatttga taacctatgc 494820
gatcgaatac cactaattga gctaattgac tcaattcttt agcagcaatc catttatgat 494880
ataaacttgc ttgatccatt cccatcataa aatataactg atcatttgga tatatttttt 494940
ttagatatct aattgtatcg atcgtataat tttttttact actatcttga tcaatctcgt 495000
agcggcaaat ttcaacattt ttatagcgct ttaaagcaat ttccaacatc gctaatcgtt 495060
gttgtttagt tgctcctgta gagtctttcc atgggttgtt agcagtcggc ataactaaaa 495120
ttttatctaa ctttaattgc ctgattgact cttcaatcac gcgtacatga gaacgatgaa 495180
ttgggtcaaa actaccgcca aaaacaccta tttttatcat ggtaatttat aaatttcctt 495240
ttcacttggg cgatataaaa taattgttct tcctaaaatt tgcacaacat ctgcttttgt 495300
tttcatactt aactctagcg caatctcatt ttttgaatca gcacatgatt caagaatttt 495360
tactttgatc aattcatgag cttctagagc atcgtcaata ccttcaattt gagtttgatg 495420
aactccttct ttaccaattt gaaaaatagc atttaaatta tgtgctatcc ctcttaaata 495480
tcttttttgc tttcctgtta acataacccg attcctttct aaattaatgc ttctctaata 495540
aaaacaccaa caccttgtgg tgcatgaact ctaacattgg cattgggaca attaacactg 495600
acaaatccta gaccggaaat aacaatatca attttaccct ctggtaattt aaaatcataa 495660
cttgccattt cattaatatc cttaatactt tcaatttccg gcatcagagt caagtgccga 495720
ttatataaat tatcactgtt tcccaattta gttctatgaa tttttaataa ttttggaaaa 495780
aaacaagtaa aagaactacg cggtccttta atgaaatcaa cgcgtgccaa cccaccaaaa 495840
tatagtgttt gttggtcgtt taattgaaaa ttaattggtc ttaattcgct tttaggaata 495900
attattctca aatcttcatc tttaactaaa tgagccatct gatgattatt aatgatacca 495960
ggcgaatcat ataaataatt tttatcatct agtggaattt caattaaatc aagcgttgtt 496020
ccaggaaatt cacttgttgt tattaaatta tcagttactc ctgcataatg ttttaataaa 496080
gaattaatca acgaagattt cccgacatta gtaactccaa caatataaac atctcgacca 496140
tgacgatatt cattaatctt atctattaat aaatctaaat tataattttt ggttccactt 496200
gataaaataa cgtcaatagg tttaattcct gattctttca actgtcttct tagccaatgc 496260
tcaattttac gatcttttag tgattttggc aaaatatctc gtttgtttcc aagaactaaa 496320
atatcattat tattaagatg ccgtgataat ccatttatta agctgccatt ataatcaaat 496380
aaatcaacta aataaacaac aagacaatca tgatttccga tttcttgaag aatttttaaa 496440
aaatcatcac tagtaagatc tgttttttgt aattcatgat aattttttaa gcgaaaacag 496500
cgtttacaaa gaattacatc tttttctaaa gcatttttag gcacaaaacc tatctttttt 496560
tcgtcttcac tttgaattat ggctccacag ccaaaacatc taatctcttt agtcatacta 496620
tctccttttc aaaccactcc cattgtacct tattttaagc caattttaaa gtaaataatc 496680
gttaaaataa aacttggtat aattttattt atttggatga atataaagat ttttgtccta 496740
aattaaaaga ttgacaatat atatgtatta gaggtgaaat ataaatgttt tcaacattat 496800
tatccttact tactaatggt ttctttgtct catacattaa atcaaaatct tttgagttac 496860
cactaacagc taaagaggaa gaaagatatc ttgaacagtt ttttaatggt gacaaagagg 496920
ctcggaatgt tttaattgaa agaaatttaa gattggtagc tcatattgct aaaaaatacg 496980
agaacaataa agatatgcag gaagatctga tttcaattgg aacaatagga ctgattaaag 497040
cagtcgatag ttataaacaa aaccataaaa ctaagttagc cacttatgct tccagatgta 497100
ttgaaaatga gatattaatg catcttagaa ctaataaaaa gactaactta gatatttcat 497160
taaatgagac aatcggtatt gataaggatg gcagtgaaat agttttaggt gatatcattg 497220
ccgcaaaaca agaggagttt atcgatatag tagataaaaa ggatacttta gataaattta 497280
caacatattt tagtgttctt gaaccccgcg aaaaagatac tttgattatg cgttatggct 497340
tgaataatac caaaaagtat actcaaaaag atattgctaa aaaattaaat atctcacgtt 497400
cttatgtttc acgtcttgaa aaacgtgcat taattaaatt attgcgtgaa catatgaaag 497460
aaaaaccgta aattatataa tttacggttt aaaaatcatc ttcttttaga atatcttcta 497520
gagatatttt ttcatattta attggttctg tttttttggg tactttaaca accgctttat 497580
ttttggtagt ttcaacctca tcactttcaa aatcatctaa taaggtatgc tctttgggtt 497640
gtttaaagat ttctaaatca acttcggttt tcttagctac atcataatcg cttgttgaaa 497700
ttggagaatt tatataaaca tcatcaatta cttgattagc cgttaattta ttagctacac 497760
ttggtttttg ctcaagatta gcattattat agtcagttgc tttaaattca aatgaagtct 497820
gatcgtttaa agtgactgta attaattgtg aattatcaac aattacggaa tcttttacat 497880
aaataatttt agatttagga ttcttataca ataaagttcc ttttgtagca cgattgcaag 497940
gtgttatatc gccaatttta attcgtttaa ccccaccttc ttcgctaata acgattaatg 498000
aactgctaac taatggatta aaaatattga gactaactaa ctcatcattt tttaaattta 498060
cagctctaat cccagcggct ttgattccaa cgattgaaac ttcttgctct gaatataatg 498120
ctccataccc agctttagtc gttaagataa ttccttgatt attatcagtc aatttaacat 498180
cgactacccg atcatcattc tttaatccca tacatttaag gggctttgaa tatcgagtaa 498240
cttcaaaatc ttttaaattc gtccgtttga tttgaccatt ttttgttgct agcataacgt 498300
acaatggtaa attaaaatct tttaccaaaa tagttccgat gattttttca ccagcattta 498360
gttttactaa ataactaaca tgtttaccag catctttcca tttaaattct tcaatcttat 498420
gaactggaat aaagagataa tttccagcat cagtaaacag caataaatga tctaacgtat 498480
tggcttgata cattgaaact agatagtcat tttctttttt gccgaacgga ataccttcac 498540
tagccttgat agaacgatta ctaattcgct taatatatcc atcacgggta atagaaacat 498600
tgatatcctc agataggatc attgctttct catctatttt aatttcttga acctcatcac 498660
gaatttttga tagacgtggc attggatatt ttttcttaat accttttaat tgatcaataa 498720
taactttacg tagaacctca tcactgttta aaatattatt taaatatgca attcgattat 498780
ctaattcttt attttcattt tccaatgtga caatatcagt gtttgttaaa cgatacaatt 498840
gtaacattac aattgcttca gcttgttttt cgctaaaacc atatttttca atcaagttat 498900
ttttagcatc gcttttatct tttgattgtc taattgtttt tacaacctca tctaaaattg 498960
aaattgcttt aatcaatcct tcaacgatat gtttacgctc attagcctta ttaagatcat 499020
gaattgaact tcgtgtaaca acatctattt gatgtgcaat atagccatct aaaatctcaa 499080
ttacccccat taagactggt cgcttatctt tgattgcaac catattatag ttgtaatttt 499140
tttgtagatc agtatttttg tatagatagt taagagtatt ttgtacattt atatcctttt 499200
ttaaatcaat aacaatccgt aatccagtac gatcagattc atcacgaact tcgataattc 499260
catcgatatt gcgattaaat cgaatttcat caattttacg aactaattct gctttgttta 499320
cttcataggg aatttcagta ataacgattt tattcatcgt tttctcttca atcatttcac 499380
tagtactacg aacaatcact ttcccacggc cacttttaaa ggcatttaaa attccttgtt 499440
ttccttcaac aatagctcca gttggaaaat ctggaccttt aataaattcc attagttttt 499500
ccaaagaaca gttagggtat ttaattcgat gaatcgttgc atcgattact tcttcaagat 499560
tatgtggagg aatatctgtt gcataaccgg ccgatattcc cgttgcacca tttactaata 499620
aatttggata ggccgctggt aatacagttg gttcatattc tgtatcatca aagtttaaag 499680
acattaatac tgtatcttta tctaaatctt ttagtaattc aacagcaatt gctgatagac 499740
gagcttcagt ataacgcatt gctgctgccg gatcgttatc aatagatcca ttatttcctt 499800
gcatatcaac taatggaaca cgcattttcc aatcttggga taaacggacc attgcatcat 499860
atactgatgt gtctccatga ggatgataat taccaataac gttcccaact gtttttgctg 499920
acttacgata tggttttgaa tataaatttc cttctttata catcgaataa agaatccggc 499980
gctgtactgg ttttaaacca tcacgaacat caggtaaagc acgatcttga ataatatatt 500040
tagaatattt tccaaagcgg tcacccatga tagtttctaa tgacataatt atttttttat 500100
ccacgcttat tttctcctta ctcaattgca aaattatctt ctaatgtaaa ttggacattt 500160
tgttcaatcc attctcgtct tggttctact ttatcaccca ttaatacaga aactcgacgt 500220
tcaacaattg ccgcatcttc aattgatact tgaattaaag tccgagtttc tggattcata 500280
gttgtttccc ataattgaga agcattcatc tccccaagtc ctttataccg ttgtacatta 500340
tatccacgac caattttctt ctttgcttct tctaattcgt cttcttccca agcgtaaacg 500400
atatcttcct ttttcccact tttctttgac actttataaa gtggtggtaa agcaatatat 500460
acttttcctg cagtaattag atctcgcata tatcgataga agaaagttag taaaagaatt 500520
tgaatatggg caccgtcggt atcagcatcg gtcatgatga ttactttatt ataattacta 500580
tctttttcgt taaaatcagc tccaacgcca gccccaattg tattaataat tgttgcaatt 500640
tcttcatttt ttaaaatgtc agccattgct gccttttcag tattaacaac ttttcctcgt 500700
aatggtaaaa ttgcttgata tttacgatcg cgaccttgtt ttgcactacc gcctgctgaa 500760
tctccttcga ctaagtatag ctctttacgt tttttatctt tagattgagc aggtgctaat 500820
tttccactta aaattttttc ttgacgtggg cctttacctt tacgagcagc ttctcgagct 500880
ttacgtgccg catcacgaac ttgagcagct ttaatcattt tcttaacaag attatctgct 500940
gtttctttat gctcttctaa aaaatatgta agtttttcat aaactactgt atctacaaca 501000
tttcgtgcct ctggcgttcc tagtttagat tttgtttgtc cttcaaactg taaataatgt 501060
tcaggtactt taattgaaat aattgccgaa agtccttcac gaacatcatt tccttctaaa 501120
ttcttgtctt tcttttaata acccatattt acgagcatat tcattaaacg ttctagttaa 501180
agctgatcta aatcctgttt catgagttcc accatcacca gttctaacta aattcacaaa 501240
agataaagta gtttcttgat aaccactagt gaactgcata gcgacatcaa cttctatttc 501300
attatttgta ccctcaatat taataatttc attaagagtc tctttttcat aatttaaata 501360
ttcaacaaat gctgttaaac cattatcgta ttgataactt atctctttac ctgtacgttc 501420
atcaactaaa tcaattttga ttccttttaa aaggaacgca ctttccatca atcgttcact 501480
aatcgtagaa aaattatatt cataaactga aaaaatgctt gaatcgggca taaaatgaat 501540
cgttgttcca gtttgatttg atttaccaat cacttttaac ttcccaactt tactaccacc 501600
atcttcaaat ctttgctgcc aaatttttcc atcacgataa attgttactt caagccatga 501660
agatagtgca ttaacgaccg acgccccaac tccatgtaat ccgccagaag ttttataacc 501720
gccgtcttcg ttaaacttac cgccggcatg taaaatcgta aggattactt ctgttgtagg 501780
cttacctgaa gcatgcatcc ctgtcggcat tccccgacca tggtcagtta ctttgatact 501840
gttatcctta caaatcgtta cttgtatatt atcaccaaat cctgaaagtg cttcatcaat 501900
tgcattatca acaatttccc aaactaagtg atgcagtccg cgtgcatcag tcgaaccaat 501960
atacattcct ggtcgcttac gaactgcttc taagccttca agtatttgaa tatttgactc 502020
atcataatta cttttagctg ccatataatt catctgcctc ctttaatcac ttgtaccatt 502080
atacctaaat tttaggtttt ttcaaagatt attgcatttt tataatgata atatataata 502140
gtcacaggtg ataaaaaatg gatataatga tttcaataat tttaattata ctcagttatc 502200
tatatggatc gattcccttt gcattagtta ttgggcgatt agtctataaa actgatgtta 502260
gaaactatgg ttccggtaat ttagggggaa caaatactgg tcgtgtttta ggaaaaaaag 502320
ctggtgttgc tgtaattctt ttggatgctt caaaggcatt attagtaatg cttttaacta 502380
gttacttatg ttcactatta aaaatgaata atgatttagc atatatatgt gctttagctt 502440
gtgtgattgg gcactgctat cctgtttttg caaatttcaa aggcggtaaa gcagtttcaa 502500
ctgcaatcgg tttttttatg gctgtcaatc ctataggtgc tgtcttagcc ttagtcgttt 502560
tcttcattgt tctaaagctt tctaaatatg tttcactgtc ttcagtttta gcatcgtctt 502620
cagtattgtt tgcaattccg tttttaaata tgtcaatgac tggtaaaatc gtaactgcag 502680
cggttatttt actgttaatt tatcgacaca aagaaaattt aattagaatt aaaaatggga 502740
cagaaaataa aattacttgg atgtaaatat gctcgttaat acataaagtt gtgaattatc 502800
acggcttttt tatttaataa aaataaggat gcattatcca aaaagagatg catccattag 502860
gtaattattt atatgtaatt atttcactac tttttagatg actatcatca ccaatatatt 502920
taatcttaaa ttcttttcca tcatattcaa cttcacttaa agaacaacca cgaacaacat 502980
atttattgat ttttgttaat tcggatgttt tataattaag cattattccg tgaagaataa 503040
taaataacat cccatgaatc gtaataaaaa ttgtatcatc atgatgtttt ttataaatat 503100
cattaaaaaa atcttttaac cgcatttgga cttcatgata tgtttcacca ccaggagtgc 503160
taacatcatc atccggaaga ttccataatc gattataaat tggatcattt aataattcat 503220
taataaggca tccttcgtat ttaccaaaat tcatttcttt taatcgtttg tcaacaagaa 503280
aatgatcaaa taatatttca cttgttgctt tagcacgttc tatcggactg ctataacaat 503340
aatcaatttt aagttctgtg attcttgctt ttagcaactt agcatcttct atgccttctg 503400
ctgttagcgg tgaatcttgc catccctgta atcttttttc ttgattccac aatgtttttg 503460
agtgtcgagt aaggtatatt ttcataaagt aaaaataagg gttacccctt atttatattg 503520
tgacataaca gatgacatga tttttttaat ttgagcctca ctaggtttac gacccatttc 503580
catatacatt gcacgaatca ttttttcgtt gattggtgga tttttttgta attgtttttt 503640
aaacatataa cgtgctgcga aaaaaccgat aatcgcacca acgattaaac ccaaaattat 503700
attcaacata tttatacctc caagttttta gattgctcta ccattataac ataacttttt 503760
gatatttggt ataaaatatc caagaatata tttgtttttt tatttgcttc aataattata 503820
tagtaatcat gaataacgca aatcatttct tcttttgtta attgattatc aataacatgt 503880
ttatttttat cccgatgata atcgtatcgg tcttttaact tgtattcgat aaagtcacta 503940
actccttcat tatttccaaa taaacactcc atttgcttcg taaaaaaaac atttttaggt 504000
tcaatattaa tgatttgatt tttcacctct ggatattgtt caagtaatcc aacaacatta 504060
ggatttaact tatatatttt atatgtattc atttctatca ccatgattag tgtatcaaag 504120
aaaatctaag tatattgtca aatcatgccc aaaaatcaat aaaagtgatg ttattacatc 504180
acttttacta gtccttataa aatatcttta acgtttttta ctacattttc aactgtaaaa 504240
ccatagtttt taataacgat atcagcaggt gcactagcac caaatttatt tactgacatt 504300
gttttaccat ctaaaccaac atatttatgc caaccaaaat cactggccat ttcaattgat 504360
aaacgagctc taacattgtg tggaagaatc tcatctttat atttagcatc ttgctgttca 504420
aataactcca ttgatggcat tgatacaaca cgaacatcga tatcttcttt caataattct 504480
tctttagctg ccattgctaa atttacttca ctacctgaag cgataataat tgcatctaat 504540
ttattgactt ctttacctac aatgtaggct ccatgacaaa caccttcgta tgaagttgca 504600
gtcattgtgg taacattttg acgagtcaaa attagagctg taggattatt agttgattca 504660
actgctaatt tccatgcaga tgccatttcg acagcatctg ctggtctaaa tactcgcata 504720
tttggcattg aacgtaacat tgttagttgt tcaacgggtt gatgagttgg tccatcttcc 504780
ccaactgcaa tcgagtcatg agataatggt aaaatgattg gcaattccat caaacaagcc 504840
attctcaaag cgcctttaaa gtagtcagag aaaactagga aaccacctgc agatactttt 504900
attcctgtgt gtaaagtgat tccattcatc attgcaacca tagcaaactc acgaattcca 504960
aacgctaaat tacggccatc ataattttca acactaaatg ttttttcgcc tgcaatattt 505020
gttttagttg aagatgctaa atcagctgtt cctgacataa atgtaggatt ttgttgagca 505080
acttcttgaa tcatttctaa tgaagtgttt cttgttgcat cgttatgacc aggtgaatat 505140
tttttcatta tttcatctaa atctaatgaa aagttcccag caatagcatt ttctaattct 505200
tgagcaagtt ctggataagc atttctatag tctttcatta accgctgcca cttattataa 505260
cgattttttc cacgtttaat acatgtatta gcaaaatcat cataaacttc ttcaggaaca 505320
taaaattcgt catgatcaaa gccataagaa attttagcat ttttaccatc ttcttttcct 505380
aatggattac catgaacttt attagttcct tcattacttg aaccaaaacc aatcactgta 505440
tcaataatga tcaaagttgg tttatataat tcttttttcc ctttacggat tgctttttga 505500
attgcactaa catcatttcc atctgttaca cgaattactt gccatccgat tgcttcataa 505560
cgctttttca catcttcact aaaagacatt gataacggcc catcaagcgt aactttattg 505620
gcatcatata aaacaattaa tttacctaac gataaatgcc cagctaaaga agcagcctca 505680
taagtaacgc cttcttgcat atcaccatct ccgcataatg catatgtata gtgatcgaca 505740
acatcataac cctcacggtt atattttgaa gctaagaatt tttctgctaa agccattcct 505800
gctgccattg gaattccttg acccaaaggt cctgaagaag catcgacacc atcagtaata 505860
tcacattcag gatgtcctgg agtaatagaa ccccattgtc taaaattctt taagtcatca 505920
atagaaattt gataaccaga taaatgcagc attgaatata acaatgctga agcatgacca 505980
gaagccaata caaaacgatc gcgattaaac cattttgatt gtttgtgata aaaatccatt 506040
tccttagtaa ataacgtata gattgccggt gttgacccta ataccatccc tggatgacca 506100
gagttagctt tgttgatggt atcaatacct aacgcacgaa ttgttgcgat tgataagctt 506160
gatgtttcca ttaatttcta attctccttt tttgcacata aaaacttatt cttattatac 506220
acaaaatcgt ataaattaaa ataagttttt cgacaaatta tattaatttt ttaatttttc 506280
atcttttagc ttttgtggcg tgatatcatt tccttcttcg tcaacaactt taacacccat 506340
taattgttgc ttaaacccac tacgaaaagc ttttaaatat ttttgacgta attctttttg 506400
ttcttctaat tcagcctcac tgattgtacc atcttttttc tttttagcca attcattaat 506460
tcttacaatt aattctggat ctatattact cattttaatt ttctccttaa atataaaaaa 506520
ggtagagagc tttagatatt tccctgttaa gtacaggtgg gcacctttaa atatacttta 506580
ggatccctat tcaaagacag gttttcaaca ccgcaattta gatcaggttc ccttatctat 506640
gatgtggaaa tttatttact ctctaaccaa aattattata acacagccac cttaagtgtc 506700
aacactttaa gcatagcgat atgtgacaaa attattactt tttcttaaca atacaagtac 506760
tagtgtattc aatatcaaaa tatttaaaag tgttataaat atctttaagt tgaatatcag 506820
ccacctcatc gactaaattc aaagcgatag ttccttcaaa ataatagcga ctgaataaat 506880
tcgcaatact ttcaggacta ttaaataaat ttataaataa tccaatattt ttctttttaa 506940
ttctttcaaa gtctttttct tcaatcttaa gctctttaaa atttttaatt aagtcgagca 507000
aatgattttt taatgtttca tagtcatcac aatcacatcc aatttgaata aatgcatagt 507060
ctctttcttg cgtaaaactt gcactaaatg aatcgttaat aatcccttta tttaaccagt 507120
cgttatataa ttttgaactt tttgaaaata gtaagtcaaa caatagattc attgataact 507180
cacgtttgat tttttcttta ggttcagaaa gaatttcatt tattttaatt gaaacaatta 507240
ttttattcat ttcaacatcc attgataaaa tattttcttt tgttttaacc ttacaaggtt 507300
caatgttttt ctggcaaata attggttgtg ctgtttcaaa attcttttta gcctgatttt 507360
ctctaattac atttatggct gtatcggcat taatattacc tacgacaaat aacatcatat 507420
tactaggatg atagaaagta ttatagcaag tttccaacat tgttttatca gtgcgattta 507480
cggtttcaac tgttcccgca atatcaatgg ctacaggatg attattgtaa aggttttgaa 507540
ttgatccaaa ataaacacgc caatctgggt catcatcata catttttatc tcttgaccaa 507600
taatcccttt ttccttctca acgctttcag gagtaatatc taatctttga acaaaatcta 507660
atagtaactc aatacatgga tattcatttg aagtagtact aaataaatag gctgttctac 507720
ttgatgaagt gaaggcattg gtactggcac ctaatttagc aaactcatca gaagcatcag 507780
taccattcat atcaaacatt ttatgttcta agaaatgagc tattccgtct tctactttaa 507840
tcatttcatt accatttaaa ggtacaaaag ttgtatcaat agcgccgaat ttggttgaaa 507900
acaacccgta agttttttca aacccttgtt ttggtaaaag ataaacttct aatccgttat 507960
ccattttttc atgatataaa gtttctttta aagtatcaaa gtatattttt tccattattt 508020
atcactccct gttaataaga aaattgtatc taagtgtact tttttgctgg cagcaataat 508080
ttcttctttg gatacacgca ttaatttttc taaatattca tcatttgttt cttgaacacc 508140
tgttaaatcc cggttataag ccaatgtaat caaactaatt ggttcatctt tagtttttgt 508200
taatgagctt tttaacatca gttttgctaa atcaatttca tcattactaa aatcaccatt 508260
ttgaatattc tttaattctt gggcaattaa gtccttagct ttttgatagt cactgccttc 508320
aattcccgca ttaactgtca taatcccact aaatgcccca tagcttgatg atatatagta 508380
acataaacta tgcttttcac ggacaatttt gaataaccgt gattgtgaaa atccgccaaa 508440
aattgcatta aatacagtca tcgcataagt gccaggatcc ttaaagttac aatcaacaac 508500
atatcccata tttaatttag cttgagtaat atcttgtttt tcaactactt ctaagatgtc 508560
attcttgctt gatttgaaat tagtaactgg atcaagcggt tgactgctgc tgctaaaact 508620
tagattttct ttaaatacat ctacaatact ttcatcaaca tcaccaacaa catataaatg 508680
tttaacatca ttctctaagc attcaactaa gtatttatag acctcttcat tagtgattcg 508740
atcaagttct tctacatagc cattattact aatggataaa aaaccaccct cacccatatt 508800
tttgaataat tgatctaatc cgtacataaa tttatcatca ttttgaacaa tcaaacgctc 508860
ttttaattct tttttcttaa tagcaaaagt ttgttcatca aattttccat ttctaacatt 508920
gggatgaaat aaaacgtcat taaacatttt gatttgttgc actaataaat tttcttgata 508980
cggcaaaaat gtttcattaa tacaaacact tgaaatattt aacacttgtc caattccctt 509040
agtcgctaaa ttagtgccaa aactcattcc ataaagatct tccaaatgag ttgataatgc 509100
ttgagttgag ggatagtttt ctgttcctcc agtaagcata aaagccaata aagaacgttt 509160
agtaacattt tcttttgtta actttccttc taattttaat gacattgtta tattcttaaa 509220
ttttttgctt ggaataacat gtagtgtata tccagctaat tgataacttt ttttcataaa 509280
aatctccttt acaaacctaa tgtatatatt atacactaaa aaataaaaat taaaaccgca 509340
tcttaaaaag aacaagttaa aaagaacatc atgatgatgt tctttttaac aaattaacgt 509400
tttgctttat caaaaggttc tccagcagct tttggtgctg cagaattttt tgaagtaaaa 509460
gctaataata ttaaagtggc aacataaggg aagattttaa aaactacacc tggaactcca 509520
gaatttaata aaaatggaat tgaagcatat gttacagcta aagtcttagc aaaagcaaag 509580
aaaattgctg acaatgcgat tcgccaaggt gtccagttac caaaaattaa aactgctaat 509640
gctaagaatc catatccagc aactgtacta gaatactcac ttgttattgg gattacatag 509700
attaaaccac ccataccagc caatattcca gatagaacaa cgcctaaata acgcatttta 509760
tatacattta ctccagcagc atcagcagct tgtgggttct caccacatgt cctaattctt 509820
aatcctgttt tcgttttata gagatacacg tatgtagcaa tcaaaatagc aataccaata 509880
aatgtagaaa gataaaaatc tttaaaaaac atatcaccaa ttattggaat gtctgaaaga 509940
actggaactt tttttattaa aaattcatta ctgaacggaa tacttttcac tccaccaaaa 510000
atagtcttag caacaaaaat tccaaaagca ggagcaaata aattcaatgc agtcccagaa 510060
atagtctgat cagctttcat actgattgca gcaaaagcat gtaacagcgc aaataatcca 510120
ccgattactc cagaaattaa taaagctact agaaacaatg cttgcccact taaccagccg 510180
gcattttgag cagtatgcat aaaccaaatc ccaaaaaaag ctccaaaaat cataattcct 510240
tctaaggcaa tattaactac tccagagcgt tcactaaaca acccgcctaa agcaacgatc 510300
aacagaggga tcgaaaacat caagctttgt ctaaataaga aataaaataa atccattatt 510360
catcccctcc aatcaaagct tgttttttat cttttttacg cccctttcgg cgttctaaaa 510420
ttaatcgaat aaacaatgtg aaagaactaa aataaataat tgctgcaaca attacatcga 510480
taatttctac tgcaatatgt actgcttgaa catagtttcc gcctaaattg atatatgcga 510540
taaataatgc agcgaaaatc acgccaagtg gattgttaaa ccctaataag gcaacaggaa 510600
taccattaaa accttcagcg gctaaaactt ctgctgttcc tattgttcgt ccagttcccg 510660
ccatataaac caaagctcca cctagtcctg caaaaaaacc ggcaattacc atcgataaaa 510720
caatactttt tttctcattc attcccgcgt atttactcgc atctggatta tatccagttg 510780
cttttagttc ataaccaaat gttgttttat tcataataac ataagcaaga atacatacac 510840
caatagcaat gaacgttcct aaattaatgc tcgaaccatt aaaaacctga tctaatccta 510900
aatttggtat tgctaaactt gtaggaatag tatacgattc agcgccagtg ggattataca 510960
taaatttttt tactccttca attactaata gcatcccaat ataattcatc atgatactag 511020
atattacaac attaacattg cgataagctt taagtaatcc aggaacactg gcccataagg 511080
ctcctgctaa tcctcctgca agcacagcaa agatccaacg aatagattcg gggataaaag 511140
ttgcattaaa agctataaac attgaagcaa aggctcctac aatatattgt cctggtgttc 511200
caatattaaa tagaccacat ttaaatgcaa aagccactga aagaccggtc atcataattg 511260
gtactgataa atataatact tcaccaacgc ttttaattcc acgataaaaa ccacctcgaa 511320
gtaagattga aaatccttct aatgcctgat taggaattac taaaaacata attagtagtc 511380
caaaaatcaa accgcataaa atcgcaatca aagaagataa aaatgatttt gtccatgctt 511440
tatttttcat atccaacacc tcgctttgat cccgccatat acaatcctaa ttcttcaacg 511500
ttagtttctt ttggatttaa gtcagtaaca atctctcctt catacattac cagaattcga 511560
tcactgacat tcataacttc atcaagttct aaactaatta gtaaaaccgc atgtccctca 511620
tcgcgctgtt gaatcaactg tttatgaata aattctattg ctccaacatc aagcccacga 511680
gtaggttgaa cagcaatcaa taaatcacaa ttactttcaa tttctcgcgc aataattgct 511740
ttttgttgat ttccaccaga cattcctcga acaatcgaat gtgacccttg accagaacga 511800
acatcaaatt tttcaatcaa tctatctgca taattataaa tgttctcaaa ttttaagaaa 511860
ccatgtttct ggttatcttt attaaaataa ttttttaaaa tcatattttc tgctaaatta 511920
taatctagta ctagtccatg cttatgacga tcttcaggaa tatgggaaat tccttttaaa 511980
tttctttgcc taaccgaata atgggttata tcctcattat ttaaaattat cttacctgta 512040
tatccagtta acattccagt taatgcatat acaagttcac tttgcccgtt tccatcaatt 512100
cctgcaatac agactatttc accacgttta acttcaaaat taatatctgt caaggcattt 512160
ttcatagcgt ttttcttaca ataattgaga ttttcaacct ttaaaaccgt ttgcccagga 512220
gttgcttttc ctttttcaac aataaaatta acatcacggc ctaccatcat ctttgacaat 512280
tcttcttttg aggtcgttgt aacatcaaca gtagcaacgt actttccttt tctaataaca 512340
gtacatcgat cagctaccgc tttgatttca tttaatttat gtgtaataaa aataattgat 512400
tttccttcgg caactaatcc tttcataatt ttcaataatt cttcaatttc ttgaggggtt 512460
aaaactgcag ttggttcatc aaatattaaa atctcattat ccctaaagag catttttaaa 512520
atttcaactc gctgttgcat ccctactgtt atatctttta taagagcatc aggctcgata 512580
tttaaatgat attgtttgga aagatcaaga acctttttac gagcattgtc tttggctaat 512640
aatccatttt tagtttcttc aacacccaaa ataatattat ccaaaactgt aaatgtttcg 512700
actaatttaa aatgttgatg aaccattcca attttataac gattagcatc gttaggatca 512760
tttatttcag caatttcacc gttaatttta atgcatccct cgtcaggttg atacagcccg 512820
aataggattg acatcaatgt tgattttcct gctccatttt ctcctaacaa agcatgaatc 512880
tcaccttttt ttagttgtac ggttatatta tcattagcct taattccagg aaattcttta 512940
gtgatattca acatctctat tacatattcc ataccgtcac tcctttctta tctaatgttg 513000
atttttctcg gttagattga gaaatacttt taaaaaaagc gagttgtctc gctttttatt 513060
atttatcata tgtaatattt acattagtga caggtacttt agtaggatta ccattatcat 513120
tgtcagtaat atctgtcatt gatttgattt taatttcacc acttgccact ttatcaaata 513180
cttccttgta tgctgcagca ttaaaatcac ccaaacgatc aaagtcatct ggtaaaccaa 513240
cataaccacc tgatgcatct aatgtttcga taccaccttt aaatttatca tttttgtaat 513300
cgactaattt atcataaact gtctttttta catcttttaa tgctgaagta ataacaacac 513360
ctgtcttgtc atcattttgg ttgctatcaa caccaattgc atatttgcca gcttcttttg 513420
ctgcagggaa aatagagtta caaattccac caccgcatga gaaaatagct tcagttccag 513480
catcatacca cttagcagct ttagttttaa tcgcaggatc ttcattaaat gttcctgtat 513540
atgtatacat catatcgact gtaacaccta attcttttgc tgcatcattt gctccttgaa 513600
tatatccata accataatta attacagctg gtaatgcaat tccacccata aatccaagtt 513660
tagtgtgacc tgctttgaca gctgcatacc ctgctaaata tccaggttgt gtttctgtat 513720
acaatgcaca ataaacatta tcaccaggat caactggatt agatttagta ctatccttct 513780
catctggaac tgttggtgta gcatcaatca agataaattt gacatctttg tatttatctt 513840
gtaattcacc aattgcatta cagaatttaa aacctggaca aacaataatt tttgccccat 513900
tttctacagc ttcttcaatt tgtgatttgt agccagcatc atcaaaactt gctggtttat 513960
agtatttgat agttgcatca tgatcttttt gatactgttc aacagcttcc catgcagact 514020
gattaaacga tttatcgtta atatcccctg catctgttac aagtgctact tcaaattctt 514080
cactgctact accaccgcat cccactaata gaaatgagaa tacaacaagt gaagccaaaa 514140
gctttttcat attcaatttt cctccttcaa taaactatag ctttatttta acattcttcc 514200
ttaaaaattg aaagcgatta catttattat tcccgttttt ttataaaata tacaaaaaaa 514260
gacatctatt tagatgtcct cttcttgata tccgcgaatg taaacttcac gtggcttaga 514320
gccaatctgt ggtccaataa caccgtctgc ttctaactga tcgatgattc gtgctgcttt 514380
attgtatcca attcgaaact gccgttgtaa taaagatgta cttgcttttt gagcattgat 514440
tacaaaactg cgacacattt catattcttc atcttcctct tcttctttcg aagcagcact 514500
tggtgaagta gtatttaatt ttacatttat gtatttgtca tcatagctag cctcctgctg 514560
agtagcagtg tggtgagtaa ttgcactaac ttcatcgtca gatacaaaag caccttgaac 514620
ccgcaccggt gaactagaac ccattggtga aaataacata tctccttttc ctaataattt 514680
ttccgctcca gaagcatcca aaattgttcg tgaatcaatt ccagaagaga ctgcaaaagc 514740
aattcttgat ggaatatttg ctttgatgac tccagtgata atatcagtcg atggtctttg 514800
tgttgcaacg atcaaatgaa tccctgctgc ccgcgccatt tgagcaatcc tcatgataca 514860
atcttcaact tgtttgcttg cgaccatcat caaatcagca acctcatcta aaataactac 514920
atgaaaaggt aagatctcta attgttcgtc caaagctaat tcttcatttt ttttacgtgc 514980
atagttatta tagccttcga tattccgtac atttgcccca gcaaaaaggt catagcgatg 515040
ctccatttcc actacaactt cctgcaatac tgcagctgcc tttttaggat cagttactac 515100
tggagctaat agatgaggta taccattata attagttaac tctacttttt taggatcgac 515160
aagaataaat ttcacctcat ccggtcgagc acgcatcaaa atactacaaa taatagtatt 515220
tacacaaact gattttccac ttccagttgc cccagcaatc aataagtggg gcattttatt 515280
taattccgca taaataatct taccactaac atccttgcct aaaggaacta acaacttgtt 515340
atcctgtaaa tcttttggaa tgtctttaat tacttctttg aaacttacca ttgttgcaac 515400
actattagga atttccactc caactgccgg tttaccagga attggtgctt caatacgaat 515460
atcttttgca gctaaggcta attttatatc atcttgtaat tgcataattt tattaacacg 515520
cgtgcccgtt tccaatttta attcatattt agtaaccgat ggtccaataa aaatatcact 515580
aattgttgcg tttactccaa attcatgaag aacatttgtt agtgcttcag ctttagataa 515640
tgcatttcct ttattatcac cagacttttt tgctgtagga ttttttaata gggataaggc 515700
aggtaaacga taattcttat taatcttttt cttaggttta gacatatcat tttcatggat 515760
ctttggttct ttatctttaa tttctaaagt catagaatcc tcatcaaatt caaatgtaga 515820
gggtactgat tcatcttctt ctaaatgagt agtatggatt cgagctgaac tctttccagg 515880
gggatcttgc tcttggcttg aagtattttc atcaccaaat atctcctctg gaaaaaagcc 515940
ttttgcttta tcttttttag gggtaaaaaa atctgtgaat ttactagcgc tttgatgcat 516000
tttaatatct tttttagtgg gtttcttttt ctttctttca gcaacatttt tacgatgttc 516060
taaataaaac ttactaccta acaaagttaa accaattact aaaataaaac cagcagcaat 516120
cattgccccc gttttatcaa acaaagcact taaaatgcca tataaaacag ctcctagaaa 516180
tccacctcga ttacaaggtg ctgttgagac atattgatta attactttca ttccaaccat 516240
taaatcatca tttaaagatg acataaaagt caaaactgcc cctaccacca tgtataatcc 516300
gattgcacga ggaccagtaa attttggtaa tttagcaaaa taaattacat acccactaat 516360
caaaaccaat gaaatataac taattccaac aaaatttcca attatataag tacacaaaaa 516420
attcagttgt tcaccaattg gtcctaattt cattgccccg acaacaatta aaaacaagcc 516480
tactgtagca atgattctta cttttaaatc ctcactaatt tgatcttgtt ttgatttttt 516540
tgaacgactt gttttcgcca tgactcacac tcccaactct aactcaatca ttataccata 516600
tcatatctat ttagcaaaag aaaaagcaag gataaacttg cttaaacttc gatgataatt 516660
ggcaagatta caggtctttt acctgtctct ttaataataa acttatttgc tttatcttta 516720
atattttgtc gaacttctac tgcttctagt ttaggatcat ctttcatttc actaacacat 516780
ttttcagcaa tatcaataac tcccttaata atatgttcag aatcccttaa ataaacaaaa 516840
ccacgtgact gaacatcagt attggcaata atttcatgag ttttactatc aatcgtgact 516900
ccaataatga ctactccatc atttgacaac tgaattcgat catcaataac tttatcacct 516960
acatcaccaa caccaattcc atcaatcatt acatcttcaa cttcaatagt atcgcgataa 517020
tcttctagtt ttccactttt aaacgataaa atttcaccat tatcgataat agcaatattt 517080
tctggtttaa ttgccatatt tttagcaact tccaaatttg aaataaaatg ttgatactca 517140
cccttaactg gtacaaaata tgtcggatta aaaatttgta taattacttt aatatcttcc 517200
tgcgatgcat gcatcgaaca taattcttta ttttttaata catgaatatt tgaatctgtc 517260
ttatataatt catttaccgc tttatttgca attttttctg ttccaggaat aactggagaa 517320
gcaacaataa atgtatcatt tttatttaat tttaaaaact catctccacc atcaatgata 517380
tcacaaatat catgatagat tctttgcggt gtcccactga gcaacactac taaattatca 517440
tcaattcctt ttttaccaat atcagtagaa aaagcaataa gattttttgg tacttgaatc 517500
actgcttttt ttaaacgctg tccaatgcgg acaatactat ttgtgctatc atatttatca 517560
cgaccataaa aaacaatttt tcgattatat ttcttcgtca gttcaacaat ttctttagtt 517620
ctaaaaatgt tttgagcata acttgaaata atgattcgtc cttcactatc ttcaaaatat 517680
tatcaatttt atctgtcaat ttatgttttg gtgatgtata acctggattt ttagaataag 517740
atgactcaca taaaagtgct aatacacctt tttttccaat ctccatcatt ttttgaatat 517800
cacatctaaa tccttctggg gcaccaaaat caacaataaa ttcaccgcta taaacgatat 517860
atccattatc agtccataaa gccactccaa cactaccagg aatcgaatga gttactggaa 517920
aaaattcaac aggaatgcca gcaataataa ttgaatcatt gcgttttaca cgatttaact 517980
gataactcac tctaaaatta ttatgttttt tatgtcgctt gatcatttgt tcaattagat 518040
cagctgttag tgctggagca taaactgggg cattgaccgc ttctaacaag taaggcaaag 518100
ctgccatcac atcatcatga ccatgcgtta tgatgatagc tacaactcgt tctttatttt 518160
cttttaagta atcaaaacta ggaataatga tatccactcc taatttactt acttctggga 518220
atctaaaccc ggcatctaaa ataaaaatct gttcttttat ttcgatgcag tacatacttt 518280
tacccatctc agcctgtccg ccaagtggta aaattttaac aacatctttc ttcatttttt 518340
cctccattat tataatctat attatttctt aatcatcgct gaaaaacaat ctttaccata 518400
ttaacatatt atagtatcgt ttgctaatac tttctacgtt cattgtatca aaattctcaa 518460
gaaaagagaa atgatttaat ttttactaac atctttaaca tgtaatatta ttaacacaat 518520
aacctttttt agccgtgttc atttaagaaa ttatttagca aaagtgagat cgtaaatttc 518580
atcttgttct ggtaaatgcg taacataccc aattggtatt ttattttccg tcacttcaat 518640
tatagtttta gctcctgctt ttccaaaagc accgcataat tcgatgcagt caactccctc 518700
aataaataat tttttgccac aatacttgct tctgctaaat tagtaacgcc aattatttgt 518760
gctgtctgtt gatggattgc ggcatgatca tatttcaaat taaaatctcc catgattata 518820
aatgcaaatt tcattatatt gtctccttaa aattcaaact ctaatcttta attagacttt 518880
acgagtatct actttttcat agttatctag ccgtttttaa tagtatataa catccgcctc 518940
attaaataaa taaatttaaa gtatcttttt ttatttcgtg attcaaaaat aatggagaaa 519000
taaattaata tttctccatt attttattca attgttcttt tgactcatca ctgattttaa 519060
ctaatggcaa acgtaactta taaagaatat tgctactttg gctcaacgaa tattttaatg 519120
tacttacaat attatcttga taaaaatatt taactattaa tttaaaaaaa tcaaaatata 519180
aatcattatg ctgagtaatt aattctctat actttttata acttagatta gttaagttac 519240
taataagtcc atcataatta ttaatttcat tttgcactag catctcttct ataccgtata 519300
gacctaaccc gttatttcta ataatctgat aacctgtgct atttacttca gtaatcaagc 519360
cagttatatt ttcatgtttt tctttcaatt ccaataaatg attaacagca atcatatttt 519420
gcttatgttg ttgaataaca atcgatttat tagttgcagt agcaattaga tcaagatgcc 519480
taatcaatcc gttttgggtt aaactaaaaa tttctggtaa ctcgatcata tagccagcaa 519540
attcgctaat gtctttaagg tctcctatct gtttaattac tttttttgta catgattcac 519600
taagctgcat atatatttca agaccaggat agtgatagca aacatatcgt aataagtgtt 519660
tttgttctaa aaaagtcaat gaagcagctt cccctgtcct gctgccaata ataaatttat 519720
tatttccttg atttactaat ttttcaatat gattatctag cgcttgataa tcaatcatat 519780
catcaatatc aaagggagta attaaattag taaaaatatc tattttaatc actccttaca 519840
accaaatcat gtaaaagatt caaatcttgt ttttgatttt ttgctttcac ataataacta 519900
tcatgttcat ttttagaaac aattgcaaat ttttcaagaa aattccgata aatctcatca 519960
ttttctaatc cacaaccaac aaaatgtact tttgtataaa gatctatttt agtataatca 520020
gtttctagtt tagctaaatc ttcttcaaaa attaaataat catcgtcaaa gcaatcatga 520080
aggaaactat aatcgctttt agctattgtt tcttcaaaac gaattagcca ataattaaaa 520140
tcaattgaca ttgttcggat atttgtatca tcatgattaa tcaaagtacc aatcctatca 520200
tctttaaaag aacgtaactt gattttaaag ccatcttttt tatacccttc catcaatgct 520260
ttgtaacaaa tgatccgagc tttgtgcttg gctaaatcaa gagcttgacg atagccaata 520320
tgcttgataa gtcgtgcttc attaatatat ttaggatcac cagtaaaaat gccacaaaca 520380
tcactataaa tatatacctc atccaaattc aaacgtcgtg ctaggtatac tgctgtataa 520440
tcgctatccc ctttttctag aatacgaata tttttaaatt tatctattcc ctgaaatcct 520500
ggcacgataa tgacatcata tgtttcaaaa tacttattga ttactttggt atctaagcca 520560
actaaacgat tatgcttaac tttaagattt aactgcatac ttgaaagcga gattgcatta 520620
attccttgtg atttcaaatt actagataac acgatactac ttattatttc tccacaacta 520680
agcaatcgac aatgttcatc gtagttagca ttaagtgcta gtgcatttaa tgtatcagtg 520740
gcataagcat ctggataacg tcccatagca cttacaataa ctaataattt atgatccaaa 520800
ttattaatta taacattagt aactagtttg attgaatcat ttgtttttaa agcagttcca 520860
ccaaatttta aaactctaat catcttttac accctcaaaa acgggctgga gctgattatt 520920
attaattgca ttgattactg tttgaattac aagagtctca tcaaataaca tgctatttgg 520980
tttttttatg cagtcatctt gatacattgg gacaagataa aaatgtttag tatttaaaat 521040
ttgcatgata tttttaccag aattacttaa agcatcgttt gtcgcgattg ctaaaacaac 521100
attatgttca ttacgaagtg ttgatttaca agccattgtg acagcattat cgtttatccc 521160
tatagctaat tttgctaatg tgttgccact acagggcatt acaatcatta gatccaaagg 521220
aattttgggt ccaaatattt cactgtctac aacattagta attacttttc ttttagaaag 521280
tttttctaat tcatcaatta attcgtcagc tttattaaaa cgagtattac aatttaaaat 521340
tttttcactt gcaaatatat ataaatcaca ttctaaagct gctaattctt ttattacagc 521400
cagcgtcttt tgtagcgaac aaaaagaccc tgttaatcca attccgattt tcttgttttt 521460
aagcatattg atcaactgcc cgtttaattg ctttataaag cgcttttgca ctactatcat 521520
aggcatactt agtcggaagc tgctttaata gatgataact ttcatcacga tcacaagttt 521580
ttaaaccata tggtgttgaa gcaacatcat aaatcttaca attaacatct tttgttttta 521640
gaatatcgct gtcaattatt tgactaggaa tagtattaat aacaaaatca tacccattta 521700
aagtgagctg atccaaccga atataacgat atcctttttc aacaacttca tcatgataat 521760
gatcactgcg attactaatg ctgactttcg cattaaattt ttcaagttta gctgctaaat 521820
cgcgtccaca atgaccataa cctaagatta acacattaga atttgacaaa ctaattgaat 521880
tatcaattat catatacgca atcactgctt catcactaat atgtgtattt tcaacaacaa 521940
agtcttcatc actatacaag taacgataat taaatccctt taacttactt aaataacata 522000
atcgctgatt ctttaataat gaaagtacta tagcattatt tttaaaatca acttgttcaa 522060
acccctgacc atctttacct aaataaataa tatcacaaga agatatcagc ctactatctt 522120
cttgaatttg ataaccatct gcaatcatta gctttgctaa ttgtttacaa cgattatcat 522180
ttccatttat ataaactatc atattccacc tctactataa aatatgataa ttaatttagt 522240
ttgttactcg ataatcactt tcatcatgaa agtaattcaa aacccatttc ttcagttaat 522300
aaggctaata taatttcaat acgttcttgt aaattttcta ctgcttcatt taaaatctct 522360
ttttcagaca tttctgttga gaaatcaatc aagacaaaag aacacttaat aacatataaa 522420
tgcccactgt tttgcttacc tacagatata tgataattaa gctgcaatcg atttttttca 522480
tcgtgactat atccaatttc tatctgtgct cgaacatccg tggcacttgc tgatacggtt 522540
tcattaataa tgtttgcatg aatacttttc attttgattt tcattttaaa atcctcctat 522600
aatattattt actattcaat gttcattttt tcttttatta tttacaattt tttagaattt 522660
tattaaaata acattattgg gggttgaaaa atgtatctat ttatgtttat aatcaccttt 522720
ttaatgtcgt taaaaacctc ttgggcatat aataatttta cttacttatc ttatcaacct 522780
catttaagaa tatattattt aatttgggtt acattaattt catgtttctt attatttaag 522840
gtaattaaac tttttaaaca tattacgtat ctaacgattg caaataagtt cttaatcggg 522900
agttgtttta tttccatgct gacaggttcc tatttacctt atcatcctga taatgaaaat 522960
attgtttcgg ttctccatgt cctcatttca tcatcaggaa ccatctccct attatttatt 523020
atccaattac taattaatcg tatcatgtta gatgattatc agttttataa aaaaatgtct 523080
actctattta ggagtttagt cttattaatt ggaatgttta tcattatgtt tggcgtaatc 523140
aatagtattg ttgaactttt ctttactttt actgtgttgt tttcacttgc tcaaattgaa 523200
aagcactatt tttaaataaa ttaagcataa taaaaagtag gtatacttaa agaaatttta 523260
tctttttata tacctacttt tattgcttta atttaaaaaa ttattcttaa ttatccgaaa 523320
tagcgtttta ataatccagc aaacgctttt ccatgacgtg cttcatcacg tgccatttca 523380
tgcactgtat catgaattgc atctaagttt aatgctttag ctttcttagc taattctgtt 523440
ttacccatag ttgctccatt ttcagcttca acacgcatct ctaggttctt ttttgttgaa 523500
tcagttacta cttctcctaa taattctgca aattttgctg catgttcagc ttcttcataa 523560
gctgcttttt cccaatataa tccaatttct ggatatcctt cacgatgtgc aactcttgcc 523620
attgctaaat acattcctac ttctgagcat tctccttcaa agtttgctct taattctttt 523680
ttgatctctt catctacgtc tttagcaaca cctacaacgt gttctgctgc ccaagtcatt 523740
tcacctgttt gttcaacgaa cttgtcagcc ccaactttac atactggaca ttgttctgga 523800
gctgcatctc cttcataaac atatccacat acagaacata caaatttagc cattataatt 523860
atctcctttt tatattattt atttcatcat cacctataat taacagtaat gattactgat 523920
attaatatat catattttaa ttttttgtca atatatatac tcacctaaat agaaaaaaag 523980
ctgaattttt attcagcctt cttctaaaag agagagagaa atatatcgct attaacaatt 524040
ttctttttta cggtatagcc ataatccagc aatacttaac attcctaata ctaagaatga 524100
tccaataact acatcgtcac cagtttttga actagttgtt gtatctgatg cagtgtttcc 524160
attaattata ccatcttcat taggggtaac tgatggtttt atttctaatg catcaattgc 524220
tgcttgcaac ttagcctgta gtttatctac atcagtttgt agcatttctg aactatcttt 524280
taactctact ttgatagttt taataatatc caataattta ttataagatt cttcagtata 524340
tctattagca tcaagtgctt cagcagtttc taataaaata ttaagatctg ttaaatctcc 524400
tcgttctaca agtttttcag cagcagcttt caaagttttt gttaattcag ctatatcttc 524460
actgctgttt tcatcattta aagcatcttt aacttctgtt agtactttaa caaattcttt 524520
ccatgtagaa gcagtataat tattttcttt ataactatca attaatccat ttatagcatt 524580
aatttcatca gcagttgctt ttaaaaccaa tgccgcacgt gtttcttgta atgctgttaa 524640
agcatcttcc aattgtttaa ctgtcgcatc atcactggca attaggtcat gtgccacctt 524700
taatgcatct acaaatggtg ttgcagtaga tgttagatat ttactagtat ctaaattatc 524760
caactcattt gtatctatat aattttgtaa tacttcttta ctcactgaaa cttttgtaat 524820
taagtttgat ttagctactt gtaatatgtt gaccatatca gcaacttctt taacgctcaa 524880
ttcttcttca cctttagcta ataaagtatt agcctcatta actttatctt gtaatgcctc 524940
ccatgttgaa tcagtataat catcagcaac taatgcacca attttattta attcatcttt 525000
aattaattgg acattaccac gagtaactaa attagtataa gcaatttgta attcactata 525060
tgctttgatt attaatttct tatctcctga agcagttgat aaaacttcat ttgcctgatt 525120
caatttgcta acatacttag cataagaaga cgcagtataa ttattttcat caacatttaa 525180
tgagttaaca tatttttgta atgcttctaa ttctggtaaa aattcatcat catttaatct 525240
tacaatttca gaaattgttg ggatattatt tgcttcccat acaatcttca attcataagt 525300
catatcaaat ggtaaatata tctcatttag tgatttgctt aaagtgccta cttgtaccca 525360
ctgtttttct tcaccaacca ttactaaagc cattacctta gcattactta ctgtcccttt 525420
ttgaacgata tttattttct taacatctaa attatcagaa agtgtatatg taatataccc 525480
tgcatcagta gtatttggtt tatatgctgt agttaaatca ccgtcaaaca tattttgtgg 525540
tacaaatcct tgtacttcca ctgcatttga ttcaaaagta ggatcatttg ataccggaac 525600
atactcacca tcattaatta caatttcatt gaataaaact gcacgattat tatttgttgc 525660
tgtcattaaa atttttaaat aacgagcctt aacattatca gcagtccctt caaccaatac 525720
cttattagga taagtacttg atgctttata acctgcatca gaatttatac aagtaacaga 525780
ggcatcattt ttattttcta ctccatcacc aattgttata acctttgtcc aattttctaa 525840
atcattagaa ataagaatat cagcatcccg aatataattt actgcagaat cttggcagaa 525900
catttgaatt ttagaaatat ttctttcttg tcctaaatca taaataatgt attgtccttt 525960
ttgtggcaga tctgcaaatt ctgttgttgt atcaatatta ccatcaaaag ccgcaccatt 526020
attacgacta tcttctgcta ctccccatga actattaatt cccattgttg tttcatataa 526080
tgaaggagcg tataattcat ttgaatgtac ttcaaatcta ttaagatcaa aagtaatggc 526140
agaatcagta ttattaatta ttcttacata acgagcatca ggtaattcac tagttttagt 526200
ttttacagta gtccactcaa gtgcattttt agatgtttct atagtcaaat tatctttatt 526260
catatcaaca acaatttcac taatatcttt aattcttaat aaatcaacac caatatattg 526320
accttgagtt aatgtgatta cctcatcata catcaattta gttaaatctt ctttactttc 526380
tgttatcaat ctatattctg tatttgtgta tacatttgta tcatcataat ctttaatagg 526440
atcaaattga gcaacatcaa attctgagaa aattacccaa gaatttttct gttcattatt 526500
tactaaacga acatatcttg cctctactcc acgtaaattc tcatcaataa catctttgcc 526560
gttagtaaca ccttcatatg atttatatgt tgtccaatct tgaccatcag tagagtattg 526620
taaactgtat ttaagccact tgtcacccgc attacgatct ccaccaataa cagcatgaac 526680
ttttcctatc tgaattgttt ttccaaaatc ccaaccaata aaatcaccaa cgcggctagt 526740
atcaccaggc ttagtattaa aatctaaagc tgtagtgtta tctccatccg ttagatttga 526800
ctctgttcct ttgtagactt cccatgtatc agtatacata aatgtctttt ctatagctgc 526860
aggattgctt acactaaaat cataaacttt ccaccaaaaa ccagcactat cattttgtaa 526920
atttaattct aaatttctaa ttctaactgc tttaaccgtt aagtttaatg ctgaaacatc 526980
ctcattaact gctgcttgac catcatattt tgcaatttct tgccaatttt taccatcaat 527040
tgtatattca agcgcatatt ttgtaatttt atcagtttta ctatcttgaa caaaattaat 527100
tgttcctaat tttttaggat ttttgaatgt taaaatcaat gaggcatcaa taggtatata 527160
atctttaatt gtgccacctt tatacggatc ttcagcaaag tgagcaaatg tagagttatc 527220
tccatctgtt acttttgcaa gagtaccgcc ttgtaatgac aatttatcta tagataatgt 527280
tcccatatca ttatctacaa taggttcatc tgttggattt acaacaatat cacgaattcc 527340
taaccaagta ttagatttcg cttctgtggc aatcattcta attcctttta cattttgtaa 527400
ttctaaatct tctaaaacaa cttcatttgg tagattataa atagttccat ccaaatcttt 527460
ccattctttg ccatcattag taaattgcac tttagatttt gcaaaagtat ctttagaatt 527520
actatttgta cctaatctaa atatcacttt atctacatca atagcttttg tgtaactaac 527580
accaacatat gtaccttcat ttatagaatt tggattttta taaacaattt ccgtattggc 527640
tttattatca aaaacatttg aaatagctcc agtaggtgta tcatcacgat ttgtaataaa 527700
ttttgttacc tgttttgatg gatcaataat tgatgatgca acatcagata agtattgttc 527760
cattgttttt ataaacggta caatatgttg tacccctact tccgcatatt catcatgatc 527820
aacataatgg aaattatgtg tttttgatct ttcaaaagca gcttgacctt gagcatacaa 527880
gtcccaaatt tggtcatttt cagcaccatc ttgcactgct ttgacaccat taattaaagc 527940
aatcgctgcc tcagtagtat catcccagca atctaaccaa taaattattt gatcttttat 528000
acgagtgtca cctgcttcat tacgataagt ttttgcagct gtttgtaatt ttgtgaactc 528060
gttaattaaa tcggtaaata aatcatcact gattgtatta ccactattta aagcagtttt 528120
aaattgattc aaacgatctt ttaattctac tgactcttgt aatggcgtta cacgactatc 528180
catattttga tttatcatat gttttgatag ttcttttaag gcatccgaag cagctgttac 528240
ttctgcgcta ttatgatcaa catatttaaa tgaatcttcc caaatttcat ctgcttcttc 528300
actagtttcc caaatattcc atgaataaca tgcatttcca aaaattgcca ctttacttgg 528360
ttcagattgt tgcattggat ttagaacaat accttggatc ttatttggat caacccccgg 528420
atgtaagaat gtactatatc cacccataat caagtgcttt ttagaattat cagtacaagg 528480
ccaattgatc cacatatatg gtccacgacc tacattatta gtaaaagttg ttgtaaaatt 528540
atttgaaact tcaccccaaa cacgtccacc agtcataaca atttgaacgt tttctgggaa 528600
attcgtatag taaccttggc cattacccat atattcttga gtacaaaatg gtaatgttaa 528660
ttttaaatct ggatatgttt tttgcatttc cttgatccat gcagtcatat ctttcaaagt 528720
tttaatgtag ttatctccac caacatttcc agcatcatca gcaagaattg caatttgacg 528780
aacacctgct tcaattactt gagcaaattt agcctgcatt acttttaaat cagcttgata 528840
attttcttca ctgttatatc taattgcatt attcatatac ggatgcaatg caaaaacaaa 528900
acgacatttt gattcattac cagcttgtgc taacggtttt atttttgttt caatttcttc 528960
atcactgtat aattcacgcc atttagaatt atgtttaggg tcatcttttg gagcataaaa 529020
atatgaattt aatttataat atcctcccca tttcatcaat tcagagcgat cttctgttga 529080
ccaagggttt ccataatatc cttcaatgaa tcctcgacta gctacatcag cgtaatcttc 529140
cattacaaag ttacggattg aataactatc catctggtta aagatatgat ataaactagt 529200
gattccataa aatgcagcat cagtatcttt acctaataca gtaattgtcc cattatctga 529260
ggctaataaa tatgaatcta atttatcata taatccactt gtttttaatg tgtaattttt 529320
agatacatgt ttatcaacgt atccatctga tcctttaata cctactaaga tattagtttg 529380
atcttcttta atttcatttg agatagtagc atttatcttc ttgattgcca atacctcatt 529440
cattctagct ttagtatatt catcaatacc atcttcatat acaatattaa tattttgatg 529500
aataacgtaa tcaccacttt gatattccat caaatgtggt ttaggataaa tttcataatc 529560
tgactcagca gcactaactt gtgttggcca tgcactaaaa caaccgaaaa ccattagtac 529620
tgccaaaaac atagacatca gtttatgagt atttttttta atttttctca ttatctcctt 529680
ttcctttccc gtatagttaa tatcgagtcc cattcccaaa aattatcaat attagttata 529740
cattatataa ataaatcaat acagatttta aacaaaaata aagaccaaat ataattatgc 529800
taaaaaacat aatacatatt tggtcttgcc tgcttagagt aacaatccgt atttacaagt 529860
aaatattagc aaaatattta gtaaacgtca agcgcttcca ttataatttt gcgttctttt 529920
ttatatgtat acataaataa gtttgctcgt ctggtgataa ttcataatca taacgatcac 529980
gaattaattt aacaatccga ttaatacaca gagacaatcg taaatcttct ttcaacattt 530040
cccggatatc cgctgtagta tcttgcaatt catcaatttc atccctaaaa attctttccg 530100
ctaaatactt taaatgagtt gaaattcgcg cataacctag agaatcctcc tctaagtcaa 530160
ctttcattga taatttaatc acatttagta cttcttttgt caaagtaaca attttcgttg 530220
cattatttgc cttattatcg agtgaaaagt ttactaaatg taaagcaata taacctgctt 530280
cgtcgtcatc taaccgtatc cccgtttttt cttctatata atcaagtgcc cataaaccaa 530340
ctttatattc ttttttatat aatacttttg tttcactcaa aacaacatta ggaagataaa 530400
tctcttcctt ttttcttttt actgcaaatg aaatatgatc acttatcgct aaaaatattt 530460
caccactaaa atctgtatct aattccttat tagcttgatt aacaatttta ttagttattt 530520
caaaatatat agcaggtact gtttcaatcg attgctcaaa tcgtttctgc tgatcatctt 530580
taaaaaaata tgtcttttca atcctgcttt cgtcaacttc atcaccaatt ctcttttgaa 530640
aaccgatccc cgaaccagtt aaaattatat cacctaactc atctgatatt gctgcaacac 530700
tattattatt aaaaaccttg agtatcttca atgttattgc ctccatccat ttacattaat 530760
atgtcattca tggcatcgac aataaattgt acttcggtgc ctatgataat ttgtaaatta 530820
ttttttccaa tttttataat tcctgttgct ccagtagcta atatagcttg ttcatcaact 530880
aaatcaggat tacctaattc cacacgtaat cgtgtaatac agctatctgc aaactgcaca 530940
ttatttcgcc cccccaaagc ttctatcaaa acaattgcaa tctcatcata gtcttgattt 531000
tctaatgtaa tattgtattc ctcttcctca atttcaatta tatcttcatc agtctcccga 531060
ccaggtgtca ttaaattata acgaactatc ataaatctaa aaatgcaata atatataaaa 531120
gcacaaatca atccaagtgg aatcagcata aatatatcgt tagagaacgg ggctttaata 531180
ctcaaaatat aatcaatcaa tcctgccgaa aagccaaagc ccgcaagcca tttaaatacc 531240
gcagccacaa atagcattat tcctgttaat agagcatgaa taaaatataa tactggtgca 531300
acaaacataa aagagaactc caatggttct gtaaccccag taacaaatga agcaaaagca 531360
gcagacaata aaatcgttcc aacttgtttt tttcgttcag gtctagcact ttggtaaata 531420
gcgattgcag ctgctggtaa tccaaacatc attactggaa aaaaaccagc ctgatacata 531480
ccagttactc ctttaatgcc tccagacact gttccccaaa atttgccaat atcattaatt 531540
cctgccacat caaaccaaaa gacagaattg agtgcatgat gtaatccagt aggaattaat 531600
aatcgattaa aaaatccata taatccagct ccaactggtc ctaatttcga aatcatttct 531660
ccaaatgata caaaacattc ataaaaaaac ggccaaacaa ttagtaataa taaagaaata 531720
actagcattg aagcagtcga tattattggg acaaaacgct ttccaccaaa aaaagataac 531780
gcatcaggta actttacttt cgaaaacttt ttataattat atgccactac aagacctgaa 531840
attattccaa caaatgcatt tgcagaattt tcaaaagcag cagaaacttc tgcttcggga 531900
attcctttta tcaatgctac agccggtggt gaaagcagcc tagaaacaat catataagaa 531960
acaaccgcac ttagagctac cgttaactct cgttcctgag acattccaat agcaattcct 532020
acagcaaata aaattggtaa attatcaata atcgctcccc cagattcaat caaaaaagca 532080
gcaatagcat tattacttcc ccatcctgtt gggtcgatcc aataaccaat tccctttaat 532140
aatgcagcaa ttggcatcac tgatacaggc aacatcaatg attttcccaa tctttgcatg 532200
tatttcatca ttcccatccc cccaatcaat ataggattta actgtacctt tccattcaat 532260
atatttatgt ttctaaacac attgattatt agtaaattaa tgtgtttttt ttgtccgaac 532320
gaaaatgtac tatttttcgt gcagaataat atatccaaac ctattgtatc actaaagcgc 532380
ttactttgtg ttaaaaaaaa tacaacgaac taagttcgca ctatgtaaga aattatacct 532440
tttattatca aatcatgtca atagatatat ctgtggctat atacattaaa tcataactac 532500
atattatcat tttataaaat aattggtata atataagaat atttaaagat attcttgaca 532560
tataattatt tagtcgatat tataaatata acgatgttac tattaaatta ggcattagtg 532620
attatttttt gatatcacta atgccttttt ctatatttaa aaggagataa tgaatgaatt 532680
tttttactag actattaaaa aataaaaaaa atacagtatg tgctcctgcc tgtggcaaag 532740
ttattcgtct ggaaaatatc cccgacaaag catttgctaa caaaatggtc ggtgatggtc 532800
ttgcaattga aattaccgat aataaacttg ttgcaccatg tgagggaata attagtgtta 532860
ttgctaatac taaacacgca tttgttatga cccttcctaa tggtcttcat ttactagtac 532920
atattggtat caatagagca aagccagatg ctaataattt tcagtatcat gtaaaagccg 532980
gtgactatgt ttctttagga gcagatattg ttacactaag cgataattta ttaaaagtcc 533040
taaataataa ggttattacc cctattattg tttgcaacta tgaatctcac cctattaaaa 533100
catttactac tgcttcatct gttgaaactg gtaaaaccat ttttacttat aaatgattga 533160
gtctaaatta aatgaagccc cttatttgga taaccaaata aggggcctca tttcaaaaat 533220
taggctcgtt tttttattta cagtataaaa agcgaaattt aaatttcgct ttttaacatc 533280
tattaaatta ttcctctttt tttcttaaca gccagtatat accaacaata gcaacaacgc 533340
ctaatcctgt tacataggca aaaatattta catcatcacc tgttttcgca gaatcactag 533400
caggaagttc gtttggagtc ggtgttggta ttggggctac tgttgctttt tcttctaatt 533460
tagcaaccgc tgtttcaaaa ttgtttttag cctcaataaa ttctttagca gaaatatcac 533520
ttaagttatc aagcatagct tttaaaacat tatatgcctc ttgatatatt ttagcagaac 533580
tttcagtgta tttgcttaaa tccactaatg taatactgtt aatatattct tttacttcat 533640
cagctttagc acgaactaca agagctttaa gtgcattatc aagtgctttg atactagcat 533700
caatttcttc agcagttcca ttttctaatc ttgcagttgc ttcagcaatt gcatcagcta 533760
atcctttgta actgctagtt gtatataatt cttgattaac tttattagct gtatctaaaa 533820
tatcttttag atcaccaaca actactaatt tttctttagc agcagctaat tcactaatag 533880
ctttcgcaaa ttcatcaggg tgtacaggag tgctttgatt atctataatc aactgttcaa 533940
cttttgcctt agcttctaga tacattttcc atgagttgat tgtgtaaagt ttttctggat 534000
ttgtaaccga agctacaaaa tcattttctc cttcaattgt aataattgct tcttcttgat 534060
ttgaaggatt aaatactaaa ttagtatttg ctagatcata attagcaatt aatttatcaa 534120
catctgcaac tgaagtatta tcaccattag caattgactt attaattgcc tcaatagctt 534180
tactatatgc taaccatgaa ggcgcagtgt aattattttg atcagtatgt gcattagcga 534240
taattatttc caatttactt aaatcacctt ttaatacttt attttcaatt gccttgttaa 534300
ttgctctaac ggcattatca acagttgttt gtgaagcata ctcactttca agtacttgct 534360
tacctgcatt ataagcatct ccatatgttg cagctgctgc agctgtccat gaagataaat 534420
cttccttgtt atcaattaaa gctttaagcg catcaacatt aagtgtagtg acctcagatt 534480
tgtatgttga taattctgta atattaggaa tcacatcacc ccactcaacc ttaatatcta 534540
ataagattgt attttcaggt aaaacaaatt cattaattgc ttgtgataat gttcctaaag 534600
ttacccattg ttctgcactt gcatttgtaa ataatcttgc tttaacaact gcattagaaa 534660
ttacagcact attttgaata attttaattg tgtttacttg gttattagat gataaactat 534720
agttcacata accattagca tctttaggaa taaacattgt tgaaatatcc ccatcaacca 534780
tataactaaa taatccatct cttgtttctt gactactaga tgtgaaggtt ggattgtttt 534840
gtgaaggtat aaattcccca ttatttattt ctaattcttg gaatctaacc catttatcag 534900
ctccaacttt agttctagta atttcaaatt ttaaataacg agcttgcaga tttaaaccat 534960
ctactttttt tgcattatat gaaatttcat gacttggtaa aacaaaacca atttcatcag 535020
tattttcagc ttcacctggg ttattttcat tttgattacc taaaagcatg atttctgtcc 535080
aagtttcacc atcagtagaa actgagaact ttccatgacg tggataatcc cattcgctat 535140
cagtacatat agctttaaat gaatttaaag ttatttcttg acctaaatca tatgtgaaat 535200
acttgccaac attttgtgat ccctgataag cagtagccgt agtaagatca ccatcaaata 535260
cattcaatgg tttatcgatt gaaaaattac tacttgtaat tgatttctct ttaatctcaa 535320
ctgtatttac aataaattta ttaagatcaa aagttacttc agcctcatta ttattaataa 535380
tacgaacata acgagcatca gcacttacat taccagcatt tacgttttgc cactcataac 535440
tatttttaga aacttgaatg gtcaaactat catttgttaa ttcactaaca atatctttta 535500
attcatgaat tcgatctagt tttaaaccta cataatcacc attagctaaa gtaatccctt 535560
tagctggcgt gattttagca ctttcatcta aataatcagc agttaaactc ttatattcac 535620
taacattagt aaatacttta ccattatgat ataccttagc tgctacatca aattcacgca 535680
tagcaatcca agtgttttga ttaaccttat taaccaatcg gacatattga gcagtaatat 535740
tttgatctga caaatcagtc acaatattaa ttgtattttt atatgtttca actgttgtcc 535800
aagttttacc atctaatgaa tattgtaaat cagcatcttt aaaataatca ccatcgctat 535860
cagtgttacc ttgaagaata ttaatcttac ctaaagtaat tggtttagat aatttaaccc 535920
ctacataatc acctggaata gttgtatttg caggttcccc tttttgtcta acattataat 535980
gtactttagt agttaaatca ccatcaataa gattagcatc actaccacca taaatactcc 536040
atccatccgt agtacggatc acttctttag taaattgttc ctcttctgcc ggttgtgtaa 536100
caacagtaaa ttcacgcatt gccggccatt tgtttccgcc accaacttcg ctacatacat 536160
aacgtacggc aacaacatct tcaatttcaa tattagtaac atctacttgt gatgcatatt 536220
caccatatac ttctttattt aaatctttaa aagttgttcc atcagtagaa tattgtaatt 536280
ttgcataacc aaaagtatct tcttttttat cactattatt agcaccattt aaaatatgaa 536340
caccataaat agtcgttggt ttacttagat ccacttggaa atattgacca gctttttcat 536400
atccattatg ccatgctgca gtatcattat taccatcaac aatatcagct attttacctg 536460
aatgccaagt agtaaagctt gatgaagcac taatttctaa tggttgttct gtttctccac 536520
tagcaatata gtcattaatt ggtcctgaaa gtttatcttg taaagctttt gccaaaggaa 536580
tcaaatgtgt tgatccagga ctaactttag ctgttccatt taataattta cggatatgat 536640
tttgactatt aattaattct gatgatgcat ttgagaattg attaaaagct gtaaccatat 536700
cattttcttc aattgcaatt gctgattctg taaaatgttt aattgctgtc gttaaatctt 536760
ttaaagaacc ggtaaaagat aataattctt ttttcaggtt ttcattttta ctatttgcat 536820
ggaaaccatc acaagcatca ataatcacat tcatttctgc aattaattgt tttccacttt 536880
caataattga atcaccatta gctaacttag ttttaaactc attaattaat ggttgtaatt 536940
cttcagattc agctaaaact aagccatgac cattaggttg aggattagac atatgcttag 537000
ctaatgtatg taattcctca cttgcctctt gatcaatata tttaaatgaa tcagcccaac 537060
tttgatcatc attaaagctt ttaacattcc atgcataatc agctaccgca aaaatagcca 537120
ctttagaagc ttcagcttct tgcattggat tagttactac cccacttaaa tcatcaatat 537180
taatatcagt gtgtaataaa cttcctttcc ccatcattaa acgtgaaccg ttaatatcat 537240
tgacaggcca gttcaaccag aacagtggac ttcttctttc gtcagcccct tctggtaatc 537300
tgtttctttt aaaatgatct aatgtttttt gttcaactgg ttgacacact gcttcaccag 537360
tccagaaaat tttcacatct tcagggaatc cagcatcata atcacttaat tcagaataat 537420
ccccttgcca tgaatgatta tatcctgctg gacagaaaac agaatcataa acatctcctt 537480
tttcttttgc ccaagctgat acactattca tcattttaat tacaacacta cggtctaggc 537540
taccaacatc atcaccaaga acaccaaatt ggcgtacccc agcatcgtac aattgatcaa 537600
actttttaag taatgaagca atttcttcat ctactttaga tgcattgaaa ccacccataa 537660
atggatgggc tgtccataca aatctacatt tagaatcatt tcctacttga accatttcct 537720
taatggctgc gagttcctct tcaggatata attcacgcca taaattttta tgatatggat 537780
catctttagg tgcaaataca taagaagtca ttttgaaatc accaccgaat ttcattaatg 537840
acattctatc ttcatttgac caaggaatcc catagtaccc ttcgataaaa ccacgaatat 537900
cggtatcagc ataatcttta attacaaagt tacggattgt tgatccatcc atttgattaa 537960
aaatatgttt taatgaggta attccataaa atgccccatc agtatctttt cctaaaataa 538020
caatttcacc attatttgaa gcaacaaaat gcgccccaaa tttactaaat agactctctt 538080
caacgctata gttggattta acatagccat caacataccc tccagattta tatgtaccaa 538140
ctaaaatatt tgtttttccg tctactttct gcttagatgt gctaatttgt ttattttttg 538200
actctaatac ttcagtcatt ctctttttag tagcagcatc aattccatct tcatatacca 538260
cattaacttg tgaacgaata acataatcct tatcttgata agtaatttca tgtggtgttg 538320
gataaatttc ataatttgtt tctttagctt ctacttttat atttggtgac ataaaaaata 538380
gtgtactaaa tacaaccaac attgctaatg aagattttaa agctttgtcc caaaatcttg 538440
ccatcttttt cctccctaag atttagtcaa atggattaga aaaataaaag accgatatac 538500
agaaaataat ctgtacatcg gtcttgccta atctaatagt aacaatccat ttacttcacg 538560
agtatatcat gacaattatc ccctgtcaag aaagcgatta caaaaaatgg atttatcaag 538620
catcttttga tttaaccaga aggattggtt tactatttgt gatagttgca atttcacaac 538680
ttacttgatt ggatacacat aatggatcct gtcgttgtaa aaaatactga ttcaatgggt 538740
actcagcacc atcaatatca atataagcat catctagtgc atataatgaa aaatacttat 538800
attcatcttg atacacctta tgtgttcccg gcaataataa ttgaataaca ttttgctgat 538860
caataattct aattttttta tctgcatatt tttccaaaag acacataacg ctaagaaaat 538920
gatctaagcg accgcccgtc acaccataaa tatctacttc atcataacca ttctccaaag 538980
catattctaa agctgcatgt gtatcggtca catctttacg agttggcaat ctttctatat 539040
ctaactcact taaaacattc tcgttttcaa tcgaatcaaa atcaccaatt gcaaagacag 539100
gcttaatccc ctgtttaagt aatatttcaa caccatgatc aacaccaata tattttaaac 539160
tgtcatcgag tttacaagcc agtgcactac aaatacctat cttcatttta gtgactctat 539220
tgctttcgta taatcatcac taccaaaaac atagctgccg gccactaaaa cgtcaactcc 539280
agcatcatta cataacttgg aagtcgattc attgattcct ccatctactt caattaaata 539340
atgataatta ttttcttttc tgagtgttgc cagctgtgca attttatcaa cagctgccga 539400
attaaatttt tgcccaccaa aaccgggctc aactgacatt actaaaacaa catctaactc 539460
attcaaaaat ggttttagta cttctactgg tgtatccggc ttaattgata gcccgacctc 539520
cacatcatgc tccttaatat gagcgattaa ttcattaatc ttatcttcag caactgcttc 539580
ataatgaaaa acaattaatg acgcattact attaataaaa ttatccacat atttagctgg 539640
atcagtaatc attaaatgta catcaagata catatccgtt actttactaa catcttttaa 539700
aatactatat ccaaatgata tgtttggaac aaaatgtcca tccattacat cataatgaat 539760
ccaatctgcc gctttgattg cgttaatctc ttctttcaaa taagcaaaat tagctgataa 539820
taatgaaggt gctactttaa ccatacttcc gttcctcttt cttttttaca tcttgtaaat 539880
tcattaaata atgctcatag cgttctttag atatttttcc atcttcaacg gcttttttta 539940
ccccacaatt aggttcacta tcgtgtaaac atcctctaaa cttgcattca tgactaaatt 540000
gagcaaaatc atgataggct acagctagtt cttccggtgt catttccaat tctaatgaag 540060
aaaaaccagg tgtatctcca agatatccac catacatctt gagcagttca acatgacgag 540120
ttgtatgttt tcctcgccca agagattttg atatctcatt tgtttccaat tttaaattaa 540180
tatctaaggc attcaaaaaa ctacttttgc ctaccccact ttgtccagta atcactgata 540240
ctttatcttt aaagactgtt tttaattcct caagcccatg attatctttt gagcttattt 540300
catatacccg atatccagcc tgacgataat ctttaacata ttgtttaacg ctttcatctt 540360
catctaaatc cattttagaa ataataataa ttggttcaat tcctaaatgc tcaattacta 540420
aaagaaattt atctaataat attgatgaaa aatcaggttc cttacaagaa ctaacaatca 540480
gagcttgatc aacattacaa ataggtggtc gaactaaaca attatgacga ggcaatacat 540540
tcattacata gccatcatta tcaccttcga cttcatattc aacaaagtca ccaaccaggg 540600
gcttaatctc atccttacga aatttccccc tagcacgaca ttgaattatt tgatgatcat 540660
cttcgacata ataaaaccct gctaatgctt taataattct tccttgtgac atctctacct 540720
cctaatcatc tgtaggtatt tcaggtttat aattataata ataaagtgta atagattcat 540780
tcttcttagt taccgtagta aaggcatcta aactttgacg gactacttga tttacagtaa 540840
tcttttcaat ttcatttgga tctgtaggtg ttggcaatgt ttcccgttta actgaaaaac 540900
ctttatttgt tagtaaggtc gcagcagcat caatatccat tcctttaaca tttggtactt 540960
caattttaat tcccgaagaa acagtcaatg taattgtccg atctttttca tcaggatcaa 541020
ccttatgccc ttcttttaaa ctctgttcaa caactgttcc aactgcttgt tctgaactag 541080
tttctttgat cgtaacatca aacccaagtt ttgtcagtgc ttctttggcc ttattttgat 541140
ccattcctac ataattacca agaactacat aatcaccttt tgatactgtt aaaataattt 541200
tacgatcttt ttcagttgga tctactttag ttcctttttc aatactttga tcaattacag 541260
ttcctttagt tttagaagat atctcatatt caatctctac ttcaaatttc aatttttcta 541320
atgccttttt agcaacatct tctttttttc cagtgtaatc ttcaagaaca atatatttgc 541380
ctttcgatac tgttacttta acgacatcac cttctttgat cgtcgttcct tttttagggt 541440
ctgttgcaat gatttcacct ttttcatatt catcagatag ttcttcagta atatcatcgc 541500
taatagtaac attatattct tttaaaattt cttttgcttg ttcaactgtt ttttctgtta 541560
aatcaggcat tagactagta tctggcttca ctccaagata aatcgcaaaa gcaattcccg 541620
cgataactaa agcagtaacc acaccaactc ccaccttagc ttttgtatct aaacctttaa 541680
atttattaac taatttactg aaaaaacctt cttttttagg ggctgccact tctttttctt 541740
caactggatc tacgattggt gcagtattgc cactagtaaa tgcggaacga ggatcaataa 541800
caattgttgg atcagtatct tggtcatgtg aaaaaactaa tttttcttca tcctgacgct 541860
ccatacaagt ctttatatca tccaacattt ctgttgcact tttataacga tcattaagat 541920
ttttagcagt agctttaatt acaatattct caacagactg gggaattgaa ggattaaact 541980
ccaacaatga tggtagatct tcctgcatat gctttaatgc aatattaact ggtgattcac 542040
cattaaatgg tacttctccc cgtaacaact cataaaaaac aattcctaaa gcatatacgt 542100
cactttgggc agtcgctttt tcaccacgtg ctaattctgg agctaaataa tgcaatgagc 542160
ccataataac atctgtctgg gttacctgcg ctagagattg cattgaagca attccaaaat 542220
cggcaatttt agccactcca ctatcagtaa ccaaaatatt ttgcggtttt aaatcacgat 542280
ggataatccc tagctgatga gctttagaaa ttccactaat tacttgtttc ataatatcaa 542340
ttgcttcaac tacatgaaca gcaccacgct ttaaaatcaa ctcttttaac gtcatacccg 542400
gcacatattc catgacaata taatatttat cttcatcctc accaacatca tatatttcaa 542460
caatattttt atgagaaagt gcagctgctg cactagcttc acgttgaaat ctagttacat 542520
atattggatc tttagcaagg ctagttcgaa gaatcttaat cgcaatagta cgatttaaga 542580
taatatcttg agctaaataa acatctgcca ttccgccttg accaattagt tctaacaatt 542640
cataacgttc tgcaattatt tttgccatcc tatttttcct cccgattatc aatgatagct 542700
actccgatat tatcacgtcc accattttca ttagctcgat caattaattc agtaactttt 542760
tgagatactt ttatattctt ttttaaaatt tctttaatta tttcatcatt taagcaatta 542820
tataatccat cactgcaaag caacaataaa ctatctgcaa attctaattc gataaaagat 542880
ggggttaatt cagtatctgc accaattgcc tgagtcaaaa catttttttg gctatgatta 542940
acagcttctt cttcactgat tgctccacga tcaactaaag cattaactaa agtatgatct 543000
ttagtcaatt gcattaattg atcatttttc aaaacataag cacggctatc accgacatga 543060
gaaatatata tcacattatc cattaaaatt gccacgacaa ttgtcgtacc cataccatga 543120
tgctcaacat tttgcttagc cattcttttt acaatcgcat cagcttcata aattgtttca 543180
tttacccatt ttttcaactc atcaacatta tcaaatgggg ggatactgtc aaaacaatta 543240
acaaattgat ccatcaccac ccgagaagca atttcaccag cacgatgacc acccatacca 543300
tcacagacaa ttgcaataac ttgatctttt acatttgcaa taacagtagc ctgatcctga 543360
tttttatttc gtactttacc gatatcagtc aatgcataat agttcattat ttcaccccac 543420
ttcttttagc ccttaattgt ccacaagcac catcaatatc gcgcccatgt tcttttctta 543480
aagttacatt aatatgtaat cttaatagct catttttaaa tatttctact gtttctttat 543540
cactaggttg ataaccatgc tcatcaacac tattatatgg tattaaatta acatatgcat 543600
ttaatccacg tagatagtgt gccaattgac gagcgtaaac aatatcatca ttaacacctt 543660
ttaacatgat atattcaaaa gtaacacgcc gatttgtttt atcaatatat tcactgatag 543720
cttcacgtaa atcatccatt ggatgcacct tattgatcgg catcaattca tcgcgaattt 543780
catcattagc agcatgtaac gaaatcgcca aattagtttg aattccttct tcactatatc 543840
gcttgatccc tttgatcaat ccacaagttg aaatagtgat gtgccgagcg ccgatagcta 543900
gaccatgtgg atggttaatg atccgtacaa attccatcac attatcataa ttatcaaatg 543960
gttcacccgt ccccattacg actacatgac taactcgttg atcaatatct tgttgtactt 544020
taataatttg tgcaacaatt tcacctggtg ttaaatcacg ttgtttgcgt aataaaccac 544080
tagcacaaaa tgtacatttc atgttgcagc caatttggct agttacacat agtgacttac 544140
catagtcatg aatcattaag acagattcaa tcaaacttcc atctaataat tcgaacagat 544200
atttaattgt cccatctctt gatacttgtt tttctttaat ttttaaaaca tctaaagaaa 544260
attctacttt caattgattt cgtagatctt ttgataaatc cgacatatca tcaaaactac 544320
gagcatcttt ctggtaaagc cagctaaaaa cttgtttagc acggaatggc ttttgtttga 544380
ttgaagcaaa atattcagtt agttgttcta gtgagtaatc ataaatattt ttcatcttat 544440
tttccttttt ctaatttaca catataaaat ccatcactgt cataaacata cggtaaaatc 544500
ttcttttctt caattatctt catatctgga tatttatcaa gaaattgttt tatcatttgt 544560
tcattttctt ttttattgat tgtacacgta ctatagacca ttttaccatt tttcttcaat 544620
aaatagtagg cattgtctaa caattttgct tgtaaaggaa tgattgtatc cattgcacca 544680
gaatcatgat atttaatctc cggtttacgt ttcattactc ctaaaccgct gcaaggtgca 544740
tcaagcaaaa ttttatcaaa tgattcttct gaatattttt ctttcaacaa agtggcatcc 544800
ccaacatgca gttctacatt attaacacct aagcgtttta gattagcttc aactagcttg 544860
attttatgtt caaataaatc atatgcaatt attttaccct gattattcat aatagctgct 544920
aaatgtgtag ttttacttcc tggagcacaa cacatatcaa gaacgagatc cgttggctga 544980
ggatccagca acggagcaat caactgactt gactcgtctt gaatagtgac taacccgttt 545040
ttaaaataat cagtgttagc aatatttcct gctctgtaca agagtccatc gggagaaaga 545100
ttccctgctt caaaattttc atcagttaat aattgagcct ttgtagtctt taaaatattg 545160
accctcgctg ctctggttgg tggtgtatta tcatgctgac aaatcttttt ggctatattt 545220
aaatcatact gtttacttaa catcttaact atccataagg gatggcttgt ttcaatagaa 545280
attcttttca attcatcctt ctcatcaatc tcacattttc cattacgtaa aaaatttctt 545340
aaaatagcat taacaaattt ccccgcaaaa ttatcacgtt tctttgctaa acggacagct 545400
tcatcaatta cagcataatc cggaacctta tctaagaaaa ttaattgata caatgacatc 545460
aataaaatca ttttctcacg atttttaatt tttttccctt gaatatatgg cgccaattga 545520
tattcaagat ataacttatt ttgaatcgtt ccatatacaa ttcgtgtagc caaatcttta 545580
tcatttctag ataataagct tttttctaaa tagtcattta aagtaatatt taaataactt 545640
tgctcatttt ggtattttat taatacatct aatgcagtcg ttcttgccat aaatagtcct 545700
tcctatattt gattatatgg attaaagtca caaaccacat gaactttatt tcctttttta 545760
ttataaaaat cactcatctt ttctaatact ggatataatt gtttactatt tgtaaattta 545820
atcataatac gtttacgata aatatcctgc atccgataga tcaaactatt tgccggacca 545880
agaattgcca ttttatcaag ttgtttttgt aaatactctt ttatttgcac cgcactttga 545940
ttaacaactt cttcatcttt tccttgtatt aaaatgctca ctaaatgaac atatggaggg 546000
taagctgcta attttcgtgt tttcatttct tcctgataaa aacgaagata gtcgtgattc 546060
ttgacacatt gtaacacaaa atgctcagga ttgtatgtct gaatcattac tgtaccttct 546120
ttttgaccac gtccacttcg tcctgaaacc tgttcaagca gttgaaaagt tcgctcatta 546180
gcacgaaaat cagggatatt taaacttata tcagcattta aaacaccaac aaaagtaaca 546240
ttttcaaaat ctaatccttt tgctatcatc tgtgttccta atagaatatt accctctttg 546300
cgagcaaact tatctaataa tttttgatgc ccatcctttt gtttagttgt atcaacgtca 546360
taacgaatca cttttgcacc atcaaatata gtctccagct gttcctctac tttttgtgtt 546420
cctgctccaa ctaattttaa tcgttcactt gaacaatgtg gacaaagacg cggcatttca 546480
atttgatgtt cacaataatg acaacgtaat ttgtgatccg ccttatgata tgttaaggtt 546540
acatcacaat gaggacattt aattacttca ccacaatcaa ggcaacgaac atatgttgca 546600
taaccacgtt tatttaatag aagaattact tgttcatcat gatccaggca ggtttgaatt 546660
tgttccttca tcgcttttga aaaaagtgaa taatttttat ttctaatttc atcagccata 546720
tcgatcaatt caatctttgg taagggaaac tgattgatcc gctttggtag ctcgtataga 546780
tcataaattc ctttttgtcc tcgactataa gattctagtg acggtgtagc actaccaaga 546840
ataacgggac agttatggta ttgcccccga attcgagcaa tctgagtcgt ttgataccgt 546900
ggcttgcttt cctgtttata actaggatca tgttcttcat ctaaaataat caatcctatt 546960
ttttccaaag gcgcaaatac cgcacttcga gcaccaacaa caatcttaac ttcactattc 547020
aaaattcgcc gatactcatc ataacgctca ccagcagata attttgaatg taaaattgct 547080
acctctttcc caaatttgtg tttaaaagca ttgaccatca tcggtgttaa agaaatctcc 547140
ggtactaaca ttaagacagt tttattattt ctaatcacat atttagataa atgtagatac 547200
acttcggttt ttccagaacc agtcacacca tgaattaaag cagtatgata agtatcaatt 547260
ttgctcatga ttccattgac tactttttgt tgatcaacag ttaaagaaaa ctcatgttcc 547320
tctttttgat catctaaata agggtcacga tataattcct gttcgattat taccgttacc 547380
ctctgttcaa ttagcttgtc aagcagtcca cggctataag gaaatgcttt tagtggcgtg 547440
tcgggatgtg tttttaaata ttgatacgct tcttgttgtt taacagtttt aagagtagca 547500
tcttcattaa taactttaat tactttttga tacttaattc caacactttt atttgtactt 547560
ggttttaatt gaggtggcaa cattgcttga agacagctaa ttcgtggtga caaagttaat 547620
tttgctaatg tcaaagacag ctcttgtaat tcttgattta ataaggggcg ctcatcaata 547680
acttcactaa tatagcgata tttaaatcct gctgctgctt ctaattcctc ttttgttgaa 547740
ttgctataac gacatcccgt tacatatccg attattcgtt gatatccaaa cgcaattgtc 547800
actctaaccc cactagcaat ttcagtattt gctaaataat caaaagtagt gtcaagagca 547860
tgggttggat gttctactaa tacttgtaca atatacacca tcatcatctc caatttgttt 547920
ctattctacc acatctacaa gataaaataa aagagtcgat taactcttat atctttatag 547980
caaagtatct aattgctctc ccacgttttt tatttttgga tgatctatca tcttaccaca 548040
aacatctgtt ctagcgaaaa attagcgagt aacaccgctg gtaataaagt gcaaattaaa 548100
ctagcctgat gacactaaaa gcttttattg atgattcatc aagatagata ttaagatcat 548160
gtttcaacac ataatcatga taaccatcaa aaacagttgc atgagttaat acatacttca 548220
ttgcattcac tctcttttaa aaaaaggaat ctttgcgatt cctagacatg ataaatataa 548280
ttatcttttc gcggtttagc ttctggtttc ggttctttac cataacctaa aatacaatta 548340
ccgattccta catacttttc atcaatgccc cactgcttta acaattcttt tccctcagta 548400
ctcataaaaa cttctttggc acgatgaatc caacaagaat ctacgccaac tgcattggct 548460
gcatttaaaa gattccccat tactaacgca ccatcttcta aatatgttcc aatcgttgaa 548520
tcccctaaaa cgactaccac tgttggtgct ccataaaaag gatcgttttc actatccatt 548580
attgccgcat tcaattttga tagccgctta attatctcag gattttgaat aactaccata 548640
attgcagatt gacgtcccat tcctgaggct gcatatgttc cagccgtcaa aatttcattc 548700
aattgttctt cgctaatttg ctctttttgg aagcttcgaa cacttcgacg tgtaattaaa 548760
ttattgattg tttcattcat tatactatcc ccctttttat aaggatatta tatcacagac 548820
ttaatgaata ttaagatata gataattgtt tttaagaaaa atactctata taatttagat 548880
aaaaggaggg ctgtttatgt gtaaaaaact atcaataatt ttactatgcc tgcttatgat 548940
aacaggatgc tctaaagaca agccaatttt atatagcaat cttggtaatc aagccagtca 549000
aaataaactt actaatattt taaatgaagc tgacctcccc aaagagaata ttaaacaatt 549060
cttttcctat gttaatacct ttaatcagca cgctacaccc ttaattggtg attttgaaac 549120
tttagaaaga gaacaaccag attaccaata ttttaaatat aatagcccag ttgaaataag 549180
tgatcaaaac gattctaatt cactaattcc ttcatttatc ttaataaaaa acctaattta 549240
tactaataat agcggtcacg cagatgactc atatattatg tttaatttaa atttaattga 549300
tactattgat cagtattcaa tgagccaaga agatcgttta aaattcatta ctacttttaa 549360
cagcatttct gttaccggca taaaaaataa tgaaatttct catatcaatc aaattgaaaa 549420
aacatttagt gatcgtgact ttagcgtaaa acaaaaccaa aaagcatcat tgattacctt 549480
gtggcttcac tcttccgcag ataaccgtcg ctttgttagc cactgtggtg ttttaattga 549540
tagcaatgac ggtttatatt ttattgaaaa atacggttgt ttttatcctt atcaggtgac 549600
aaaatttaat agccgaagtg aattaaaaac gtatttatta actcgaaacg atctcaaagg 549660
agatgaaaat gacggtttgc cactcgtttt tgaaaataat aaatatctga ataaataatt 549720
aataatatcc tttgaataaa ttgtaataca tttttatatt agttcctaga tgcagaacca 549780
cgactttaat ccaacagtat gatttcggtg ctgaagcact gaccatggca taatctaatt 549840
tgaatttccg agcataatga tctgcctttc gtaaatgcca gctatttgta acaactagag 549900
catttttcaa tccatttatc tgcattatat cgcggctata catcaaatta tgatatgtac 549960
ttcgagattg tccctcgata aggatatctt ctttttttac ccctaaacta attgcatatg 550020
aagccattat tttcgcttcc tgatattcat ttttaactgc cccaccagat aagattaaaa 550080
atttaatctt atctttttta tataaagtaa cacccatttc aacccgtgat ttcataattg 550140
ttgatggctc accatcgata ttagcaggat aaccacaaat aatcgcacaa tcatattttt 550200
tataacgctg ttttttatat ggttttttaa atactaataa aaatgctagt agattcaata 550260
ttccaaatcc aattattact cgtttgacca ttttattacc tcattatttt acatttcccg 550320
ggaaattgta acaaaagggc ctaatggccc cgatgtttcg ctttacgttt ttgctgtttc 550380
aatacaaata gatgctcttt ttcagccgtt cgctgctcac gacgaataat tttattcttt 550440
gccttatttt gctcatattg tcgtttcaac gcttgcatcg atttagtacc tgtttgtaag 550500
ttcatagatt gttttctaat catccgttgt aatcgcttag gattttttgg tttatcttta 550560
tgtttcgctt tgaactcagc aacaaaatta agtttatggt aattatttaa aaaataaaca 550620
tatatctcac catcacttgg ctcttgaccg aacacaactc gttcaacgta acacttatct 550680
ccatttgtta aataaaatac tccaatccaa aacggatcat caaataaaac atttaattcc 550740
aaaccaacat ccaacatatc gctatcctcc ttgaaattta cttctaagaa cggacaacct 550800
caggagggca ggttactgat gcaaaatgca caacttgact accaacaagt tcgtgttttt 550860
atcttagcaa ccatattata acttattttt cagatttatt taagaggaaa gctattcctg 550920
ctaaccctaa acctaatgcg attataataa ataaattaat acttacatca ttattcaaat 550980
aaaaatatac ttttaaatca tcatatagtc ccatcaaaac tgcaataatt aataaaaaag 551040
ctagtaaaaa tggcactttt agccgtccat catttttttt cataaaatca aacactttag 551100
catcaaatac tttaaatgca tctaacaaca tgtatattcc caaaatagct aataacacaa 551160
taatgtcggt tgggcaaaaa attaaatcaa gtcctaattt accttctaac ccttgcgcca 551220
aatataaaat taaaaccatt cctggataaa aaatatacgc aaacacctta aaatactctt 551280
taaacttttc catttttcct cctactaaaa atcagggata tttacccctg atttgtttga 551340
tgatttttta taatttcagc aattttatct tttgctgcca taacgtcatc attttccact 551400
acatatttat attcatcttt agtcgcaatt tcttttcttg cttttgataa acgttgttgg 551460
acaatctctt cttcctctgt acgacgtcca cgaattcgtc gttcgagttc ttctaagcta 551520
ggtggtacta aaaagattgt tgttgcatct ggacattttt ccattacttg aagggcccct 551580
tgaacttcaa tttctaaaac aacattttta ccttcattta ataattgatc aacgtaatct 551640
ttgggtgttc cgtaataatt accgacaaac tgcgcccact ctaataactt tccttcttca 551700
attttacttt taaattcttc ttcttcaaca aaaaaataat caattccatc tctttcattt 551760
ggacgtggtt ttcttgttgt catcgaaatc gaataagcaa gatttaaact atcgtctttg 551820
aataattctt ctcttactgt tcctttacca acgccactag gcccactaag aattatcaac 551880
attccttttt gcactgtcta cacccctttt ttttgataag ttcatcatac aaaatacgtc 551940
ttatattgtc aattgttttc aaactatata atgtcaatta tttttaatct atgttatact 552000
tacaacggtg ataaaaaatg gcatatgatg gaataatgat gcatcaagta attgatgact 552060
taaacaaaac aataactggt ggtagaatca acaaaatcta ccaaatctca aaatatgaat 552120
tattgattca agttcgtaat aatcgaacta attacaagct gctgctctcc tgccatccaa 552180
tgtacgcaag aattcagctg actaatttag actatcctac tccggaaagt ccgaatcctt 552240
taacaatgtt atttcgtaaa catcttgagg gtggttatat caaaaaaatt gaacaaatcg 552300
aattagatcg aatttgtcat tttctttttg gctgtcataa cgaatttggt gattacgttg 552360
aataccattg ttatattgaa attatgggta aacattctaa tattattctt tgcaatcaag 552420
ataaaaaaat tcttgattgt ttaaaacgaa ttacccctaa cattaatagt gaacgttttg 552480
tacaaccagg ggcaatgtac caattgccac caatgaatca aaataaagtt gatcctttca 552540
ctagtgattt tattgaaaac aataatctaa caaaaatata tcaagggatg tctccaatcc 552600
tatctaaaga aattctttat cgtcatgata atggtataga ttttaaagag attatggatg 552660
aaataaaaaa tagcgatacc ctttatataa gtagagttga tgaaaaagaa tattttcatt 552720
taattccatt aactcatcta aatcagcagg cacagtctta ttcattattc gatggtctgg 552780
ataaacattt taatttaatc gatcaaaaag aacgtataaa acaacaaaca tcaaatcttt 552840
tgaaatttat taataatgaa tatcaaaaaa atgttactaa acttgcaaaa ttagaatcaa 552900
ctctagaaga ttcgaacaat agtgatgaat atcgaatcat tggcgatctt ttatactcaa 552960
acttacattt attaaaaaaa ggaatgcgtc atgttgaact agataattac tatgatggtt 553020
ctaagattat ggttgattta gatgaaaaac ttgatcctaa aagtaatgct caaaaatatt 553080
ataacaagta tcaaaaggca aaaaattcaa tcaatgttct gcatgagcag attgatttaa 553140
ccaaaaaaga aattgaatat tttgacactc ttttaacact aatggataat gcttcatact 553200
atgatgccct agaaataaaa gaagaattag aaaatctagg atatttaaaa aagaaaaaga 553260
aaactaatac gatccgtaaa aataaaaaac cttcttttga gacatattat actaaagatg 553320
gtattgaaat atgtattggg aagaataacc ttcaaaatga ttatctaact tttaaacatg 553380
ctcatcgcta tgatacctgg tttcatgtta aagatatgcc tggtagtcat gttgtcgtta 553440
aaggtgatca attagatgaa tatacgattc gattagctag taatatcgct gcctattatt 553500
caaaagggaa aaacagtagt agtgttcctg tcaattatac tttaataaaa acattgaaaa 553560
agcctcatgg cgctaaacct gggcaagtaa tcttagataa ttataaaact atttatattg 553620
atcctgatca acattgcctc gatgaattac aaaaaaaata gatgcctggg catctatctt 553680
ttttagcggt tacatccaca tccgcttcct ccgttattag cgttgttata cattccatta 553740
ataacagagt cacctgtgtt attagctgcg ttaaatcctg tacctgctcc gttaaatgga 553800
gtagcgttag cagcacttgc gaatggattt ccattacttt gagtcatgaa agtacgttca 553860
taacgtggat aataacgtgg gtaataaacg atattattaa tatggcgaca ttcgattggg 553920
caaataattg gttgttcaac atattgatta gagcagcttg tacaaacttt tcttggtgca 553980
acgattggag tagcacggca gcagttcatt ccactgttac atcctccaca tccgcagctg 554040
ttgttacaac cacatcctga gttacaaaac atcatttcca cctcctttaa tatactatat 554100
gttcgattaa atttggtgct aaggcaaatt acacagaaag gtctaaatta tgaaattaat 554160
caaatggaat actgttgaaa acattgaagc atatacaatt actaaagaat taggcgatat 554220
gtcttataat aacgaggaca aacaattgat tctcaataat cgtaaacaat tagccaaact 554280
tttaaaaact gatttagagc acatggtggc accacatcaa acacactcag ccaactttaa 554340
agaagtatct cttaaagacg gtggcagagg tatgtactgc caagatgatg cctttaacaa 554400
tactgatgct ctttatacaa aagatactga tctcttttta ttatcatttc atgcagattg 554460
taccccagtg ttactatatt gtcctaaaac aaaaataatt gctgcaattc attctggttg 554520
gctaggaaca actaaacaaa ttgtttcaaa agtcacaaaa catctaattg aaaatgaaca 554580
ttgtgatcct aaagagatgc ttgcctatat tggaccatgc atctgccaag attgtcttga 554640
ggtaatggat aatgtcatcg acttagttaa acaaatggat ttcgatacta ctccgtacta 554700
taaacaaaca gatactacac attatttgct tgataacaaa ggtctaaacc gacaaatgtt 554760
attaaattta ggtttattga aaaaaaatat tactgtttcg ccatattgta ctgttgaaaa 554820
tgacaagtta ttttatagct atcgtaaata taaagatagt ggcagaaata tcacaatcat 554880
aaaaagacaa gcttaaagga ctataacaaa taaagatttt caatctttga tatgttccct 554940
tctagatgac aagtttttat tattttattt gtctacctag gaggaagcat atcactctag 555000
gcgttatagc cctttttatt tattaaatca gttttttcta ctttaattgt taatatttat 555060
tttttagtaa ttaaattttc cataaaatta cataaattgg ttataaatca gttacaaaat 555120
cacattttaa ctacattaac ttatcttttt acttgttaat ttttttatat gtttctcgat 555180
gaatgatata ataaaagtaa tatatataaa cgataattga ggtgattttg tcgatgaatg 555240
aaaattttaa ttcagcattc tacaagaaga ttcttgatca aattaactct aatatctatg 555300
tcaccgatgt tgaaactgat gaaattgtat atatgaacga ttatatgaaa aatacgtttc 555360
aagtctctaa cactgaagga aagaaatgct ggcagatttt acaatctgga atgaacaaaa 555420
gatgtgagtt ttgtaaaatc aaacaacttc aagaatctaa ttcacaaaaa atttgtgtat 555480
ggtatgaaaa gaacacgata acagaaaaaa catatttaaa tcatgatact ttagaacttt 555540
gggataacaa actttatcat atccaaaatt cgattgacgt tactgaacaa ctacagttat 555600
ctgtagaagc aacaattgat gaattaacag gtatttttaa tcgaaatgcc ggtaaaaaac 555660
gaattgaaga actattaact gctgaatatc ttaacgaaga ctttgttgta gttttatatg 555720
acatgaacgg tttaaaatgg gttaatgata cttatggaca tcttgaaggc gatcgcctat 555780
taatatttgt tgcccaaaat ataaaaaagc gtttgaaaga gccaaacttt atctttcgcc 555840
ttagtggtga tgaatttata attgtttttt tagatactac tgttaaaggt gtagaagttt 555900
ggatggataa tattctttta actttaaatc aagaaagaat caaagaaaac attgattatg 555960
atacctcttt tagttatgga attgctaata tccatgtaga tgaaaattta actgtttctg 556020
atgtattatc tattgctgat tcacaaatgt atatccaaaa acgagattat catattctta 556080
tgaataaaaa aaggctaaca aattcacaac ctaagtataa ttctattcct ttatttgaat 556140
ataatcgtga tcatcttttt gaaagtttat cagaaacaat tgatgactac ttatttgttg 556200
gaaatttaaa gacaagtaaa ttcatgtact cacgtcagat gatgatagat tttcgtttgc 556260
caaatcaaat tcttgataat gctgcagcat tttggggaga aaaaattcat cctgatgata 556320
aagcaggatt tttaagaagt aatcaagaaa ttgctgatgg cagagctgaa cagcatacaa 556380
tttattatcg tgcaaaagat gcctctaacc gttggattcc cttgctttgt aaaggaaaaa 556440
tgattagaga taaaaatggt aatccagatt tatttgctgg aacaattcgt aatttggata 556500
aaaatagaga acaagcttct ctagagccaa attctttaga tacttattta gatacttcgt 556560
attatattta tgagaaaaat caaagcaata aaaataattt tctttttcaa aaaagctttt 556620
actttgtaaa catatttgat cagcaaaatg atttaaaaac aaaaactgac ttacttgatt 556680
ttgtaaataa aaatattccg ggaggaatac tagctgtcca agcgcactct ggctttccac 556740
tctattgctt taatcaagcc attttagaat atacccaata ttcttatgaa gaattatgtc 556800
aaataacaaa tggaaaattt tcaaatatta tctatgaaaa agatcgtcaa tttgttgaaa 556860
gagaaatttt ccaacagctt gaaagaaatg acatttatga aattcgttat cgcatagttt 556920
gccacggagg ccatttgctt tgggtatatg aaagaggaaa atacgttatc gatgggcatg 556980
gtcaaaaact aattttgtct ttttttgttg atatttccca tgaaatgaat aatgaacaag 557040
aactacgttt cattaatgaa aatagccttg acggagtttt taaagctgca ttaattgaac 557100
attttccaat tttatatgct aatgacggat attatcgaat acatgggtat accaaaaaac 557160
aatttcacca tgatttaaat gattgtgctg aaaatctcat ttatgaatca gataaagcaa 557220
gaataagagc ccaaataacg gatttaatta aaaataatca gtcacaagct attcttgaat 557280
atcgaattaa aaaacgagac aattcaattg cctggattca tattagtgcc agctttactt 557340
cgctgcttga tcaaacaatt attatgattg gaatggtcat ggatattact aaacgaaaaa 557400
aactagaaga taagttatat cgctcacagc agttgtttaa agttgcacaa actaaaaccg 557460
gcttaaatat ttgggagttt gatattcaaa acaaacaagt aattggcaat cccgattctg 557520
cagtaatccg cagctatcaa aatcttactg ccaatatccc agaaagcata attgcacaag 557580
ggttgatcca tcctcaaagc attaatgaac ttaagaattt atatcaacgc ttagaaaaag 557640
gagctgctcc cctttctgct acaatcaggg tcaaacaaaa agatgcgaaa gataaatatc 557700
tttgggaaaa aataacatat actattgtcc agcatattga tgaaaaacca gcatgggcaa 557760
ttggcatatc agaagatgtt acagaacaaa aagaaattga gacaagaatc tataatgaag 557820
aaagtttaag gaaagttttg aatgaagata ttatattaaa catccgttta aatttttctc 557880
gtgattttat cgaagatatt tctttacatt ccaatgaaca gtatgaaaaa cagctctctg 557940
attacacata cgatgatatt tataaatatt tattacagac tattgctaat gaggatgatc 558000
aaaaaaaatt tgagaaaaaa tattctaaaa atcaaattaa tgactatatc cgtactttta 558060
ccgatattcc aacttttgaa tttaggcaga aatatttaaa tggaatgata ttatgggtat 558120
ccttaaatat gaaaacaact atttctcctc aaaataacga tgtaatatta tttatttata 558180
ccaaaaatat tgatatccaa aaaagacgtg aattagcatt gcaaaataaa gcagaaattg 558240
atgagatgag tagcttatat aatgagtcta cttcacagct aatgattgaa acattgctga 558300
agaaagaata tgatcctaag aaagtcaatg cttttctttt gctagatatt gataatttta 558360
aacagataaa tcacagtggg aatttcttgt tcggtgacca aatcattcgt caaatgggac 558420
aaatgatcaa gaaaagtatt tcttccagct gtattgcagc acgaatcaat ggtgatacat 558480
tctctatttt ttatcataat gctgaatcaa aaaaagttat ctatcaagca gccttacaac 558540
ttcaaaaaaa gctttctagt atttatcatt ttcaagatat tgagacccag ttaactctca 558600
ccggtggttt aatctatcta ttttcagaaa atatgagcta tagtcaaatt catcaatgcg 558660
cactccatgc cttagataca gctaaaagac gcggaaaaaa ccagatacta tcttatcaag 558720
aaattgaaaa agttgaattt aatttcaaga ttgaaatgat tattaaccct aatgatttta 558780
caattttatc gatgagcccg actggacaaa tcatatttaa ttgtattttc ccagttaaaa 558840
agccaataaa atgttatgaa ttattacata atcgtaaatc accgtgccca ttttgttctc 558900
aacaaatcga ctttgaacaa acaaatatgc gtgaatgttt tgtatccaaa atcgataaac 558960
ttatgtatgt taaagaacag ctgtctcatt atgagggcga tactgtaaga aaaattgaaa 559020
tgcaggatat tccctttaac ttagcatatg aaaatcagga ttcagattta caacaatttt 559080
tagaaataag ctggaaaaat atagataaaa atattcaacg agaaaatgct tttgataata 559140
ttcttagaca attaggaaca ttctttaatg cccaaaatgt tctcttattt catcaaagcg 559200
ataatcaaca aaaattttct ctgacttcaa agtggaatta taataatcaa atctctaata 559260
ttaaaaatac tcatttcagt aaggaacact ttgaaaatat tgttagtgct gtcgcaccac 559320
aaaaatactt tgtaatatta gataaaaacc atttttgtta taaaaatatt acagaactat 559380
attttgaaaa ggatgtacca ctaccattat tatttatcgg tatttataac aaaaacaagc 559440
ttgtatcatg cttgctcgtg gaaactgtta aacaacatat taacgcttca aaatctattg 559500
aggtgattgc tgatgttatt tgtaaaatta ccactattta taatttgcag actaaatata 559560
cttatgccct tactcatgat caaaaaaccg gtttatctaa ctacgattct tatattaaga 559620
ctataagaaa tataaatact gatatttatt ctacttttgg aatgattgaa ataactatca 559680
ttaatctaaa aaaatataat cagcggtatg gcatcgtcca aggtgatgaa atcttacagt 559740
tcatcgcaca aacaattact aaattttttg ataaaaaatc atgttatcgg atcagtaatg 559800
cccattttat agtgctttgt ccagatatta cgtatgaaaa cttcattcat atatatgata 559860
ctttttacca agagctaatt gaattttatg atcaatggat catttgtgaa aaagtttggg 559920
aaaagaattc acttgtgtta gaaacaatgc aagagcaatt agaggaaaaa acaagacatg 559980
ctgtaaataa aaaaatacac tctaagttag ctaaatctga tcagtcgata gcaaaaatat 560040
tagagcgttt aaatactgct tttgtaaatg gaaaattttt aaccttttta caacctaagg 560100
ctcatactaa aactaatcaa atttgtggtg ctgaagcatt gatcagatac aacgatcctc 560160
aaaaaggaat tattccacca gggcgttttc ttccagaaat agaaagagca ggattaatta 560220
gacatataga tttatttatt ctaaaagatg tctgccgaat tctcagtaac tggttaaaaa 560280
ctacttggaa gcctttccca atttcaataa attattctcg agcaactatt ttagaacctg 560340
gtattttaga agaaactaat aaaatcgttg aaagctataa tattcctaaa gaattaattg 560400
aaatagaagt tactgaatcc attggatcaa ttgattctgc tagtttaaaa aatattgtta 560460
atcaattttt agctgaagga tataaaattg ctttagatga cttcggtgct gaatatagca 560520
atatttatat actatactcg ctgcacttaa gctcacttaa acttgatcga aagatcgtaa 560580
gcgatattta tcatgatcac cgtgctaaat tagtaatcaa aaatatcatt aatacgtgtc 560640
aacaattaga tataacttgt gtcgctgaag gagtagaaac taaagaacag ctaaaagtgt 560700
taaaagattt atcttgtgat gttattcaag gctattatct taataagcct ttatctgaag 560760
atgatttcaa aaagatttct ggcatcacta acccccattg acactaaaac aaagataatc 560820
ctaagatagt tttttagttc taaagcagat gagcataaaa ctaatttacg tgattatctt 560880
tttttataaa tgcatcatag ttaaataccc tgtatcaaaa aatttctatt ttattgattt 560940
taatacattc ttttatcttg cttaaatact aattataaaa gtcatcacta ttgatgactt 561000
tttcacatat atttttaaat ctattaaaat taaatttaga tttcaagttc taattattca 561060
ttaataattt catgcattac ttgtggaatc aaatcaatta atttactagg taatactgta 561120
taagaattat cccctattac atccccacag ctgccatgta gataagttcc taaaatagct 561180
gcatttttag gtgtatagcc ttgtccaaca aaactaacga tcatcccagc taaaacatct 561240
cccattccag ccgtagccat cgccttatta gctgtaatat tacgatatgt ctctcgacca 561300
tctgtaatta atgtgttagg accctttaaa acaacagtaa caccatattt tcgagcaaaa 561360
ccaccaactt tatcaatcat atctaattca tcatcataag cacacaaacg cttaaattca 561420
ccaaaatgag gtgttaagat aataggaacg gggcactctt ttaataaatc taaatgttta 561480
gctgcaatcg tcaaaccatc agcatcaatt acgattggac aattggcata ttgtaaagta 561540
tcaattacat actgctcgct ttgttcattt aaccctaaac ctgaaccaat caaaattgca 561600
tcacggtcat aaaaaagttc ttgttccagt ttactattac gaagtttaga agtacattca 561660
ggagtaacta ttgctagcgc atcaattact ttttcacttg aacaaacaca tacaacacca 561720
cttccactat aaaccgaggc ttttgacgct aataaagcag ctcctcgata gtaatcacat 561780
ccagttaaat gtaaaatctt gccatagatt cctttatgtc cataataagc acgcggtttt 561840
aaatgatatt tgatccatga tggactaacc aatttagcaa gcccctgctc ctgacgtaaa 561900
tctttagcat ccaatatttc aactgcaatc tctcctgtat acatatgaca ctcttcattt 561960
aaaaaagcct gtttgattgc tgttaaagta attgtcttac tagcacaaat cacattacca 562020
taaggtattc ctgtatcagg atttaatcca gttggaatat caattgcgat gatgtctata 562080
tcatataaat tattaatttc ttcaattaat atcctagcta ctccacgaac ttcaccattt 562140
aatccgaaac caaacattgc atcaattacc acatctgctt tttgtgcatc acttataaat 562200
aaagatatat cttcttcatc cataaaagta attggaactt ccatctcttg cgcttgctca 562260
atataaaaat tatttgcttg agaaaattta ttagggtttc caaaacagta taacttcaca 562320
tttcgtgctc gaatatgtag tttaatccct aaacttaaac catcagctcc attatttccc 562380
ggtccacaaa caatcacgat attattataa cccaaacaat gcggtaaaat ggcattacta 562440
gctttatcca ctagttcttc gattgaatat ccctcattta ataaagcctg atcgtaagcc 562500
ttcatttgtc tacttgttgc aacatacata ttatcaccat tactttctct ataaaatctt 562560
atgtttatat tataaagcaa ttattcataa aaacctactt agaagcaaaa aaaataaaaa 562620
aagcagattt ctacactctg cttctaggac gctcatccat tatctcttga taaatcattg 562680
taacaatatt atgtggatta atattttggt ctaacagacg ttccagcatg atcatcattt 562740
ttccatcatt aatagtaccg ataatattcg ctttttcaat attttgaata tcacatatat 562800
atggaaaaaa ttcattgatt tttgtattga ttccataatg atgattagaa cggctatata 562860
aataaattat cttatcacca ttacaatcct caaaaacact tccgcgagga taattaaaaa 562920
catttttata ctgcttaact tgctttcttt tttgttcatg cttatatttt cgtttatttt 562980
catatactat ttcaatatgt tttggtgata gcatattaac cagctcataa gattttttac 563040
aatcaaatat aatcgtttca ctgtaatcaa attcatatcg taatgctgct tcacgaacaa 563100
acttagtctt attaacatat aagtttgaat tatctgtttg ataaatataa tataattgat 563160
cacccactct aataatatca ccaacgcaat aaataatcgg aacatcaaaa tgaatcaatc 563220
cctctaggta gcgtgaatta acaatcagtt ttcgctcaat cattattaaa ttattaattc 563280
caatccgatt gtaaatatct cgaaaattag ttcgcggaat cttataagtg tttgttaaat 563340
agacatatgt atttttacga tggtcatata tattcttatc aagcttaaat gtagctaaat 563400
aacgggactt ttgttttgta gaacaataat acccataaaa ataattttcg tccttagcaa 563460
cgaccaaata gggcctaatt cgatgacttt cttctatacg ttctaactca tcattactta 563520
acggcatcaa agcccatact agatttccta tcgccacttc attatattta tcttcaacaa 563580
ttggcgtaag atctataatt tcctcttttt ctagtctact aaaatacttt aataatcttt 563640
taaacaattt catcttccca ccccaagata attatatacc caacaatcaa agaatacaaa 563700
aagattatag aagcattaat cctataatct ttttgttact cattatataa ttgaaaaaac 563760
gaactgaagt gaggggtaca gttcgttctt tctatattta tatcttattt ttcagcaatt 563820
gttgcataat tagcaacaat gtaatctaca actggattac ttccccaagt tttaatagct 563880
gaagctgttg cttgaatcgt atttgcagtt actgttaatt tataattagc atcatcatat 563940
ccgtacttac ctttttcggt agttgtaatt tctttttttg ttccattttc atcagttgtt 564000
acaaccgtag taacactctt atcagttaca tctaatagtg gatttaaagt aacgttatct 564060
aataataaag ctgaactatt accgcctttg attgctccca tataataata agttccttca 564120
tattcaaccc atttacctgc ttgtgccgcc aactctatat catcagtata tttcacaaca 564180
tttggcaatg ccaataaagc cgcattttgt gttaaaccat tttcatcagt aaatgtattg 564240
cttaaagttt catcaccgcg ggtccatgac tctgttaatg ttgctttaac aactacatca 564300
acattaccac tgttttttac tgttacatct ttatttactt caactcctgg taaccaatca 564360
gttggtggag taaattcttc ttcaattgta gtatcatatt ttgctgtttt aaattcattt 564420
gtttttgtca attcctgact aaaatacgct aacgacccaa ctactcctac tgttaatgct 564480
aataataata ttccacctaa acttttttta tttttcattc ttcttcacct ttccttttct 564540
ttattgttgt tcagcaatcg tagcaaaatg atcggctaaa tacacagcca tcacattatc 564600
accaaacgca tccctaattg ctgcttttga agcttggact gtccgcgctt caactgtcaa 564660
agtataatct gcgctatcat atccatattt tccgtattga tattttttag ttacagttgt 564720
agtcccttgt tcatctgctt caacgactgt atgactgccg ctaactgttg catctaataa 564780
cggattcatc ttcacactat ttaataatcc atttgatgct tcatcttcac caattacacc 564840
taaatagtag taataatcac cataatgaat ccatttatta tgataatctg ctagattatc 564900
tttaacatct tcatattcat aaaccatatt ttgaacaaaa tttttaattg ccgcatcatg 564960
tgaaatgccg ttttcatcaa cgaatgaatt tggtaaaatt tcaccttcct cgctcaagat 565020
tttatctgga tcattaggat ccatcagatt ttcactacgt ttccatagct cagttaattt 565080
tgctcttacc acaatatcaa cgtttccagt atttttaact gtaacttttt tattaatttc 565140
aacacctggt gcccacttat cagttggaat aaattcttct tcgatcgttg tatcatactt 565200
tgccgtctta agtctatttt caacagttaa gtctctagaa aagtaagcca atgtacctac 565260
aaccaataca attgcagcta atgaaataag ggcagatagg cttttcttat ttttcatttc 565320
tatcactcac tttcttttta atctaataat gcatacgttt caggaactac agtttcaaaa 565380
gcggttcctg cgactgcttg tttattagct tgataaactt gaactgtaat cgttaaagta 565440
tagttggcac tagcatactt accattacca gttacaactg ttttattgta agttgcatta 565500
ttgggaatgc ctgtatttgg ggcaactgcc catcctgttt caggattatt agttattttg 565560
cttggttcac cagttgtcat cgtcgaataa tatactactg ttttcttagt ttcagcaaaa 565620
tcgacatctc cacttaacat gattgatttt aaaaacttat cctcggctct accacccgaa 565680
gaaattattc cgtcataata gaaatatcca tcactatttg aatatatcca tttattacca 565740
tattcttttt caacaacact agctcttgga tcagcacttg taactgtaat atcttcacca 565800
acagctgttt tccatgtttc actccacatt gctcgagaaa caatattacc agttccagta 565860
ttttcaacac ctacttcttt agtaacttta tctccgggtt cccaattatc ttttggtgta 565920
aatttttcca caacttctga cttaaactgt ccagttttta atttgttatc aacattcgtt 565980
gtgctattat aataagcaac tgccccacct ataactaaaa atgctgataa cgaaataatt 566040
gcaatcaaac tcttttttcg tttcataatt ttcgtacccc tttctcaaat atttaataac 566100
cgatatgtgg tattaataac caacaaatat acttttgtca tattacaaca ttattataaa 566160
taatcatggt ttgcttctgg ttatatttca ctttccttaa tattctattt taatgttttt 566220
attgaatcta aaaatcaata attgtcttaa cttataaaga aaaacactct aacaattgtt 566280
agagtgttcg tggcttcatt agttgtttac tgtaggtaat ccatttaaga aattttttac 566340
agtttgattt gttgcatcag tgatccaagt tgcagcagct tctttattag cttgtgaaac 566400
ttgagcagta attgttaatg tatactcagc gttatcatat aaaccatttg atttaacttc 566460
agcacgttta aatgtcgctt taatattgtt attttcatca tctaatgctt taaattcttc 566520
ttcagaaatt tttacccatt gagtttttga gtcagttcca attgatgttt tatccggttc 566580
agttgctgca gttgtataat aaaagttttt aatatctgtt ccaactacat cagcactatt 566640
ttttaaagta attgaagtta ggaaattttc tgtatgtcca tttactccaa tcatctcatt 566700
ataatatgcc catccatcat taccgtcaac ccatttatcg ctcataccat ttttatcaac 566760
aacactttca ttattagtgt ctggataagc tactgcttta aattcttctc cgttgcgtgt 566820
ccatgattct tcccatttag cacgtgctac taaagcataa tctcctgtat tatcaactcg 566880
tacctctttt gtaacagttg ctcctggatt aaattcttta ggtgtaaatt tttcgacaat 566940
atcagagcca aacccttttg tttttaattt attgtcaact gtatgtgttt gagtaaaata 567000
tgctagagtt cctacaacta ccaatgcccc tgataataca attgatgcca ctacgctttt 567060
cttgtttttc atgatttcca ctccttttta ttttttattt cattttacaa atcaatgata 567120
acaattgatg gtttgcttct ggttatattt ataactctta ttctattaat ataactatcg 567180
aagaaaactt ttcttttaca attaacagta tatctttatt tggttttttt ccggttatat 567240
tcacaaacga aaaataatat tcaaaaacaa aaagagatgt ataaaaatac atctctttca 567300
cgatttaatc aatagaaact aattgtccat tttcaacaat aattgaatcc caattttgcg 567360
tagcaactgc attagcaccg tcatctgctt gtacaccatt agcagtgatt ataatcttag 567420
atttaagatt agcatatgac attgtttcct catgtgaggt aaaattattt tcaataataa 567480
atgatttaaa taaattgaca gtctcattag attttaatgg catctttaga tagtaataag 567540
atttaccctt ttccccagta gctttatata tccatttatc ttcatcaatt ccacgaatta 567600
caattttatc aggatcttta tcactcaaga tatttccatc ttcatccatc catacctttt 567660
caaccgtcac tcttatgaaa gcatctagtt cctcagtatt ttttatatca acaattttag 567720
atttttcttg tccaatcact actggatcat catacttaat tccatcttca ctcacagagg 567780
catcgggatt agttgagctt tcgataacat ctattccaaa ttcaccaatt ctaatccggt 567840
tcttagtctc atcactatct gtaaaccatg ccagtgtggc ggatacagca agtacacaac 567900
ctagcaaaac tattagactc attatggttc ttttcttttt actcatctcg ctacactcct 567960
atctttagac tgtcactttt tctttttcat ccgctacaag gttactcaaa acaatattta 568020
ataacaatat tccaccaata attgctaccg caatatattt tgctgatgaa gcaaagatcg 568080
ttccaacaac agggaggcag aattctaatg tctttccggc tacattttga tattctacca 568140
gatttgtatc attagttgga tttgcatcgc cttttgtaac aaaagtttgt gaaatttcgt 568200
ttttcactat cactcggtga gtaactaatg tatcatcatc tactcgaaat gtgattgcat 568260
cgttttcttt aatatcctca aaagaagcag ctttgtaata gatcaaactt ccaactggat 568320
atgtgggttc catacttcca gataatacaa ctacaggctt gtagccaact accataggag 568380
caagtataag cactaatgct attatcacta cataacataa tattgataaa tagctaacca 568440
ctttcttaaa tatcttcata acctgcctcc tatcctagtt attaaaaatc ttctccagat 568500
ttctgttgat tactattacc cttataatca ctccatgtta cattatttcc agaaatagca 568560
gcagttttac caaaggtgct ttgtgcccct tcagttgtag ctttacatga ttctaaatta 568620
aatgtaattt gatagattat tcctgaataa tccaccgcat gagtatcatt tgaaacttgc 568680
tccgataaaa ccagactatc caaaatgata ttagttgttg tattagcttt taatacttta 568740
gtgtaataga aatagccgtc atttccatcc acccattcat cttgccaggc agatgtccat 568800
ttcttttcaa cactatcaac gtcaccattt acaaaatcac cattttgatt gatccagctt 568860
tgactgtaac ttaccctgat taaagcatca atttcaccac tgttggcaaa tttaaccttt 568920
ttatcaacgg tttctcctgg taaaaattgt gaatcttgat taaatttttc aatcaattca 568980
atctccggtt cttgcgttgc cattttgttt tctacattga cggtactatt atagtaagca 569040
cttgtatatc caatcgcaac aatcaaacat actgaagcaa agattaaagc taccttcgtc 569100
tttttaattt ttaaaaattt cactttatct tcacctccat ttaattccaa gtaattacat 569160
tgttagaaat aactttaaaa tcacgaccaa agtttgcttg tactgctcga tggttaacac 569220
tatcgtcatc actatactgt actgcttcac taacaaattt caaagtataa tctgctgttt 569280
gataaatttc ggcataattg ctatcaaatt taagactagt taaaacttta gctgtcattt 569340
cattagctgg aagaactttt ttataataat accagccatc accaccatca aaccagtcat 569400
tttgccatgc ttcagtccag ttcttattaa caacttcatt gccatcaact aacccagaaa 569460
taaccttgcc atcagcatct ttccaaaact ccgcataaga aactcttaga aagactggtg 569520
ctgttccagt atttttgaat tgtacttctt tttctacttg atcaaaccag tctacagttg 569580
aatctttgtc aaacttttct actacttcag tatccactgt tggtgtctta atattattag 569640
tgacagatgc acttagtttt gaccatgcgt agattccgcc cactgcagta agacagactg 569700
tcaccactac catcaatacc atcaatggtc gtttcatttt aattctacct aaatatttca 569760
ttgcgtcatc cctcaccttc tttattaatt accaactttt tttatttctg cagcttctaa 569820
atcagtagtt acaccatcct tataaccttg cacagttaac tgtggttctc ctgcatcagc 569880
cacaatattt ctaaatttaa ttccttcaat tacaaatttt ccagtagttt catcaataat 569940
atctttccat tcaatataag cattagtacc actgccacct agcttaccac cttgagcatc 570000
aattacctca aacttattag catcatattt tactcgaata tcaacatcgg tatccattgt 570060
tgtaatactt gtaaaaatac tattaaatgc attttccatc gcactactgt tatttgcttt 570120
tgtataatgt ccttcactag ctaaacgcgt taagaaacta tcaaataatg atgaattatt 570180
ggaattaaga ccaatcgtaa aaatcgtctt acctaaacct ttaccagaac gattagttct 570240
attgcctgca tcattagaat tattgttact acgattttta gtaatatcat catttttatg 570300
accataatac tttgatccat tactactttc aatgtaatta ttgattcctg ttaaatttcc 570360
actaaactta ataaaatcag cttgatttaa agcctcagct ccaacccgat acccattatc 570420
atcataatca ttataactag tattaaatcc cttatttcct ggttgaccgt cagtaaagac 570480
gattactgaa cgattatttt ctccagttgc acttgataat tgattacgaa cttcatacaa 570540
acctaaatca atttgcgttc ctcctgaagc tttaatattt ttgataccac cattattttt 570600
agttaaatat gtgtaccatg tttcattacc tgatttaata tctgataact tcacaaaatt 570660
attattagtg atcgaaccat ctgcactata tgcaaaagta attactgata cacgactgtc 570720
aggattatgt tcatataact tagttataaa tttaattaca ttatttttta aatgggttag 570780
acgactgctg ccattcattg actcatccat gctgcctgat ttatctaata gcaagacaac 570840
gtcttgtggg gcttttactg tcgtagattt aacatttcca cttacattat attcatagtt 570900
attgattgtt tcacttccag caggaagata attagtcttt tcatcagtcg ctttaaagaa 570960
tccaacatga ccaaatgaat ttgttagagt cacataacca ttagctgcat ctttattttg 571020
actaagttcg ataatatttc cactagataa gtttgtttga gcataaccac tttctgtact 571080
ttctagctta tattccattg gaacagtttc tgttacggta tatttaccaa acggtaaatt 571140
ttctaaaaga acttcttcat tattttttaa gattaaatct gttttataaa ttactgcatt 571200
ttcactatct cgaccaacca catgaataat aaatgtctta tcttcactag aattgtttac 571260
aacctttttt acagtaagag ttgcacttgt aattggcaat tcttcattaa ctgttggtac 571320
attgaaatcc aatgtagaat ctttatcaat ataattttta tagactaact gggttgggtc 571380
attggctgga taatctgtac catccttata ttcctcttta actgctacat aatattctaa 571440
atgagcttga ctgttttttt caacatcacc tacataccaa gtgatttttt ttcgaccatt 571500
ttctgtactt acaataacat aaccacgatc aaatattaat ttatcagcta cagagttatc 571560
ataacggcca tcaggtaaat ctaaaagatc aacatactgg ctcattggat cattgacaat 571620
cccatttttt atgattgttt catatcgagt cacaatctca ttagcaatat tttcataaat 571680
tccgcttaaa tcactagagg aactataggc atatccttca ccttgagtag ctacattctt 571740
caagaaacta ttaacactac ttccagttgt gtaaccaatc gtaaaaattg tatttccact 571800
tttctttgct aataatgctt cattttcagc taatgtagca gctgcattat ttaaagaata 571860
gtgactatta tttaaatata agtctaatgt aaaatcattt cttccgccct taattacact 571920
atcataattg attgcatttt ccccaaaagt atatctacca ctatatccta aagctttatc 571980
agtagcggtc gcttcgctat aatcattaac taaataacca ttattgcgtt cattatttag 572040
tttataactt cctgtcgcac caccatcact taataaaata ataattccat tttctgattt 572100
agcatttttt aaaacagttc tagctttata aagccctgct tgaatgttgg ttccaccatc 572160
cgaattattt cctaattcga catctctaat tgcttgtttt gcggtttcaa gattgcttgt 572220
tagattttgt tctactgtac catagtaatt aaatgtcaca attgaatatc gattcttttt 572280
atttccagaa attttactat tattcaaaaa ctcaattgca gcgtttttag ctttagtaag 572340
acgtttttta tcatttgaag atgtgctatt tccatgttca tcttcagcca tactatttga 572400
aatatcaaat actagaacaa tatcattacc aatcgcctca acactatcct gggcttttcc 572460
agtagctaaa tccaaattga ttttataccg attatcgcca actctttctg aagttttatt 572520
aacagtaact aggccatcac tactagtagt agagccaggg ttattttccg cttcaacaat 572580
taagttagtt ccagccgctg gtattatcat cgctaatgcc aaaaccagtg tttttatctt 572640
tctagtaaac ttattttgtt ttcttttttt agatatcttc atttagcttc ctcctcactg 572700
acgttactgt taagcttctt ttttgttacc agattaacga ttatataaat caacactaga 572760
ccagccaaaa ttatttttgc aatcattgat tggatcattc cataaatata tcctatataa 572820
ggaatattta tctttactat cccatttaat cgactaaagg caactgggtt tgaatcttgg 572880
ctactattag catcaccctt agtaataaat acttgttttt cttggtctat tttaattact 572940
cggtgagtta tcacattacc gcttacacct gagcctttaa aacttataat atcatttacc 573000
tttatttcat cagctttagc tggtttaact agtaataatt ctccagttga ataaacaggc 573060
tccatactat tcgataatac aacatttacc tcatacccca gcaatcttgg gccaagtgtt 573120
ataatcaaat atataaagca taagatcaat aatatcgttg aaacaatatt attaattttt 573180
cttattttat tcacttgctt gtttcctttt aagaataaag ataccagcag caattaacag 573240
taaaacaatt ccacctgtaa tatacaaata agtataatta attccttctt cacctttttt 573300
taaaggcgtc tgatcatcag gaacttcctc tgttccatcc ccaggtgata acggagtttc 573360
tgaatcagtc acattttcgg tatcatcacc ttggttagtt gtagtaccac cagttcctgc 573420
tccaccagtt gcagttgata ctgcagtgtt agcaggtaaa cctacaggaa tcactacaac 573480
actttcaaca tattcctgtg ttacatttaa atctcgatat acatatgtga ttgaattatc 573540
tgtttcacca attgtaattg ataaatcagc agctccaatc aattcatagc cagcaatcgt 573600
tttagctctc tcgttcactg tactgccaag tggcgctgtc ataacttttg ttgtggctat 573660
ttgaacatta tcctgattaa cataattgat cgaatattcg cgtccattag tcaaaacttg 573720
atatttggct acaaatgtca ttgcaccagt aacagcctca ccactagctg gaagggtttt 573780
attccatccc attaaataat agccatcttc tacattgata tcagggatat ccggaaaaca 573840
ttcgtttgct gctacatcga tagtaatctt attttcacca ttagcagcaa atgtaccatg 573900
agctcctgcc ctaaatgtta ctttataggt tctactagca tcaactgtca ttggattaac 573960
aaagccgacc attgcaatca tcatagctag aacaataatg acttttttaa ttttcttcat 574020
gactgcaatc ctccttatgc tttttcttct tcaataagaa tataactgca aatccactaa 574080
ctgctaccaa tccaagtaat ggtgcaatta cagttgcatc accagttttg atactttcat 574140
aaacatttct aactacttca acaatagtac tttgatcatc aagttcttca acactaaaat 574200
taaacttgat caatccttca cgattttgat acgtattatc cattgaatca ccattaactt 574260
ccaatgtcat tgttactgta gtagtttcac ctttttgtaa actagcaagt aacgtatctt 574320
cactcattct tccagaactt aaagcagcca gatcatcaag tgttccatta taaaactctt 574380
caccttcatt agtaattgta atattataaa cacttaatcc cgaagtatca gtatcaagac 574440
tatctaagac atcagcactc aaataaaatc ttaactctcg atgatcatca ttttttaaaa 574500
caatattttg tgttcgaact tcaccaggca taatattttt aaaattatca aataaatcct 574560
gactaccatc caaaaaaata aagtcttctg catcaccatc aaatgataca ttagtatcag 574620
ctgcatgaat agtagtcata gatagtgcta gtactgttgt tacaactaat gtttttaaaa 574680
tatttttacc tcgcatttta atgacctcct ccacgactat tcttctacat actgaataac 574740
atcattatta tcaattttaa cttctaagcc ccattcactc aaaattgcag attcagcacc 574800
aactttttga attgcttcag cttcaaaact taaatgagca cttaaaccag agtaacgcat 574860
tgcattagtg ttatcgatat tgccagataa tttgatttga ttaacaaata aatctgttac 574920
tgcccctggt tctaataatt ttttataata gaaataaaca acttctttat tttcatcact 574980
atcttgaata atccaattat ctttatcatt agtaatgatt tcaataaaac caggattagc 575040
atcgatcacc ttattaccgc tttcatcttc ccagtatttg gtaacagcaa ttcttgtata 575100
taaatcattt tctgatgtat tttttacaaa tgtttgttta tcttttatag ctccaggata 575160
accaaaatta aagttaatac cttcatccgt tatttgacca tcttcatttg ttgtagcatc 575220
tctcaattca attccaatat tccctgaact aagtttgtta cttgaagaag tatcggcacg 575280
gaaataggca attgcgcctc caattggaac catgatacat agaacaatca ttaatattaa 575340
tagcttattt tttttatttt ccatgatgat tatctccttt gctttaatat tgatcggtgg 575400
atacttttcc cacattacat ccatattata tgtaatggtg gttttaaagc ggttatattt 575460
tgttttagat aataactttc ttttaaaatc taaaaaagag ttaagttata tctctaaaac 575520
ttaactctga actgaagact ctattggttt tttatataat aattttgctt ttgcaacatc 575580
ataattcaaa cgatatgtag tactattata ttttgcataa aactttttat ttattctttg 575640
aatgattgta tatgcattgt ccatttcctg acacgctact aaaataatat attgtttctt 575700
attaatttta gcaaacaagt cattcactct taatgatgaa gcaatcattt cttttaactg 575760
gttcattaca tgtacttgat tttctattgt agttttagca ttaagatcaa aaataatcaa 575820
aaaatatttc ttattatctc gaagtgcatt cttaagtaaa atttcataca tatgcttaaa 575880
catgtcatat ccacagtaaa accctcgata atcagcatta ttaataatca aatcttcatt 575940
aacattttca gtattaataa tataatcttc ttctatatct tctgtaatga catcataaag 576000
ctctttaaac cgcggtgata atcctgttcc caactcttta taaaagcgtt cattcaggtc 576060
atcataatat tttaacgcat tatgatagtc ctttaattca atcaggcctt taatataata 576120
ataatgtaga ccttcgtaaa atggttctaa tagaatagca tgataattta ttgacatcat 576180
cttttcaaac tgttttcttt tcatgtagta tttgcaaatt ttgataacac agttaacata 576240
tgctgagcga aaaaattcta gcatctgttc aatccaaata gaatgattag tcgttatata 576300
taatttacct ttatatagat gatttacttt ttgagcatat gctaggtcct tatcacttat 576360
atcatcaata tattttattt tgtcccagtt ataataaaac tcctcagtat ccatcaccca 576420
ttccaacttg ggattgattt gataaccacc tttaacagtt aaaataactt cttcatcctc 576480
attaaaaata cctgatgctt ttaaatcttt acgaagtcta aaaatagaaa acttaaccac 576540
actatttgga ttttcactat ccggatataa aatatcaata atattattct tagatattac 576600
aactcctttt tgaagcagca ataattggaa taaattaatc aactgttttc ctaataattt 576660
ggttaaatca actgttacat ttccacgtga aagtgaaaac gttccaaaca tatttacgtt 576720
aatcttatca tttgccatat ctaattccct cacttttcaa gatatgttac ttgcccacaa 576780
atttatccac caaaatagtc atattctaaa accccattac agtattagcc cattattttt 576840
atttaatagt aatttattag tgataaattc ttaccacttg gtttaactat acgttttcgt 576900
tcgcatataa tcttactata aaacacgtaa atagacccaa atttatgtgt tttttttgtg 576960
cacgaaaatc tattctttcc cgtgcaggaa aagtatgatc ctcgattcta atttttttat 577020
aaaaataaca tattcattat agcactgtat ttttaattac gtcaacttta tttataagtg 577080
cggtaatact aattatattg atagaatcaa aaaagattac gaatttaaaa tcgtaatctt 577140
taattagttg ttatattcaa tttttatttt actcttacag cacaaacgaa tcctgaacca 577200
gacacagatg aaatcttaac tacatcacca gttcttgggg catgaatata ttgaccatta 577260
ccaatataaa taccaacatg tcctgatttc cataagatat ctcctggctg tgcttgggaa 577320
atactaattt gtgtacctgc attcttttga gctgaagatg agtgtggaag tgaaattcct 577380
acacgtgagt aacaccattt gacaaaacct gaacagtcaa atgaatttgg accgtctgct 577440
ccccatacat atggacaccc taatctagaa taagcagctg ataaaacact attaccatag 577500
ttattacttg ctgccccgcc ataaactgca tttaccttta ctgataagct cgcggtacct 577560
gtgttaccgg ctgcatcagt tactgtatat gtagctgttt tagtaccagc tttcgctgta 577620
ctaggagcat caactttgac attggcttta acatcaccat ctttgttatc aattgctgaa 577680
gcaatatatg cattaaaatc aacattttca ccagcattaa ctgtaattga agattttgtt 577740
aaactaatta caggagctga taaatcttta acaacaacat ttaagttagc ctcactaaca 577800
tttcctgaac tatcagttgc agaaattttc aatgtttgcg tttcatcaat ttttgaagta 577860
tcaatagatc cttcaacagt tggtactaaa gtaccatcta agttatctgt aacatttaca 577920
aaattattta aatcaaaacc acttccgtaa tctacagtaa cattttctcc ttgggttaaa 577980
ttaataaccg gagcttctaa atcgctaaca gcgaatgtaa aagttttaac agtttcatta 578040
cctgaactat cagtagcctt taaagtaata tcttgttgac ctttaacctc tgtatttaat 578100
ggggtattag cctcgataaa tggagttaca tcaccatcaa cattatcatt agccttaaca 578160
tagctagcga aatctgtact tccttttaca ggaacatcaa ttgtgtatcc ttgatttgaa 578220
cctaatgatt caaattttgg tccctcatta tctactacat taacttgaac tgtttttgta 578280
gcaacattag aaccactatc agttgcagta actgatactt tataagaacc taattgtgtt 578340
acatttaatg atgaagtgtc agctgatact tcaattaaat cacgactgtc cttattatca 578400
gtaatatcaa tactatctac atcaaatttc tcaccatagg caagatcgat ttgattagac 578460
ttaatctcag gtttttcttt gtctgctgct gcataaccaa ctagcataaa actagcaaca 578520
gctgcaatcg gaatgaacat tgctttacga ttaacgatat actcgtcaac tacattttta 578580
aagcttgtct taatatttct atccattcgt tacctccttt caataatata tccaattgtt 578640
attatattac tattttttag aaaaatctag ccctgaaagc tctttcattt ttgtcctttg 578700
gctgtatcgc aagctccgct tagctttcaa gagaataatt tttttaagat ttcttaagaa 578760
atttataaga ttttacatag tcctaaatag aaattaccat aaacataaat attaataata 578820
atattatcca gaatttataa ctaaaaatac cttattcaat gctctttaat gactcaacca 578880
tatcaatatt ttttaaaact tttcgcattc caaaatcaat taaataagta aagatcattg 578940
taataattat tgcataaaca taactcatta aattaacact tctaataaac atagctactt 579000
caacttctac cgcattaatg ataaacatat gtaaaacttt cccaattcct aatcctacaa 579060
ttgatccgat tgctgataaa attaggtttt ctctaaatac ataatcatac acctcacgtg 579120
gataaaagcc taataccttt atagttgcaa tttcactttt acgttcttga atattaatat 579180
ttgttagatt atacaagaca ataaaagcta aggccccggc acaagcaatc aatatcacaa 579240
caacactatc gatactgccc atttgatctc taaatgcttg actaattcct ttaacataat 579300
ttaatgaatc aatattgcta tccttgtcgc aatagttagt aacagtttta cgattgccat 579360
catcttctaa attaaaatac gcataattat taactggtgt ctcacctgtt agacctcgat 579420
aaaattcttc actcatatat atatggtgtt gaaaatacaa taacattact cctgtaattt 579480
taacctgata atctttttca tcaatcgtta tatttatttt atctccaatc gttactccta 579540
ataattctga taatttagct gaaataacaa ccccctgatt atttaattta attttttcac 579600
ctgtttgata attctctaga tttgtatatt tgctaagttc ctcattattc ttaaatactt 579660
ctaatgtacc ataatgatct ttacttccta caactgtgat cgtttttcga taaaaactac 579720
tgcaatcttt tacactactt aaactctcaa actcatcctt ttcttttttt aattgatcat 579780
tacttagatt acgatcaaat acaaccattc catcgtaagt aaaaatatca ccatattgct 579840
tatctgctaa agtagaaacc gaattcttga tcccaaatcc agtaacaatt aaagccgcac 579900
aaccagcaat tcctataatc gacataaaga aacgcttttt atacctaaaa atatttcgca 579960
tcgtaacttt ttgattaaaa gacaaacgtt tccaaataaa tgttattctt tctagaacaa 580020
ttctttttcc cattttaggg gccttaggtc taagcagact agctggcatc tcacttaatt 580080
cttgacgtgt cactatgtaa gtaactaata aagtaatcgc tactgaaatc aaaaatgttt 580140
ggatacaaat aaaagtatca aatgaaatct tgattggtgc accgacatta aacaacattt 580200
tacgatacaa gaaataaata atacttggga agaaatatac tcctgcgata attcctaata 580260
cactagccac gaaagtagct aaaaaagcat aaatcaaata ttgattaatt acatcttttt 580320
tatcatatcc taaagctctg aaggttccgc tttggactcg ctgttcttca accattcgag 580380
tcattgttgt taaactaact aatgcagcga ccaagaaaaa gatcagtgga aagactactg 580440
caatggcttt cattgattga caagcagaat catagcttaa gatactagca ctttcctcac 580500
gtgttaaact aatcagtttt ccagttggaa tatcatcaat ggcactgcga gcctcatcca 580560
gttttatctt agcatcatct aacgatgttt tcgcttcatc taatttaatc tttgtttcat 580620
ccagtaaaac ttttgtcttg tctaatgtaa ttttagaatc gtccagttgt tttttagaat 580680
tagtcaaagt tatcgctgtt tcatctaact gggctttgga gctgtctaaa gtaactttcg 580740
tatttgctaa cgtaattctt gcactttcca attgattagc tgtagcagcc aaaacagcac 580800
cattattgtc caattccagc ttgctcgcat ccaaagtttt tttagttgca tccagttgaa 580860
ttttagtctc gttcaacttt tcttgcatta ttgcagcatc ttctggcgta attaaattat 580920
tctcaattaa atattgtaat tgtactacac tttgattata ttgctcaatt cccacattat 580980
actgattcag tccattatta tattgattta tcccctcatt atatgcactg attccttgat 581040
catactgagc ttttcccagc tgataatcac tgactccttg atcgtactga gcttttccat 581100
cttgatattg ctttagacca ttttgatatt gacgataccc atcattgtat ttatttaaac 581160
catcttgata ctgctttaag ccactttcat attggctaag accattgtta tattgagcta 581220
atccatcttg gtattcattg ataccatcat tatattcctg ttcgcctttt tctaattcac 581280
gattagcatc acccgctaat tcctcattga cctgagcaac tttaccacta agaacttttt 581340
taatttcttt attaacatct tttacataac ttaaataatc atcactaaaa atattattat 581400
catcactgtt ttttaaagtc actcgaattt cattaaaaac agttccatta cgaagatcat 581460
atagatcttg cggtaaagct aatgattcat tgccttgagc taaaatttca acaaaagcct 581520
cattagttcc atcaccgaga gtatttgtcc cccgttcaat cgtactaaaa taacgaggat 581580
cattgatcaa tccaacaacc ttaaatttct tttcaccatt atcattagtt aatgttatct 581640
tacttcctac tttgatttta tttcttgaag cataattatt atccaccaaa cattcatcat 581700
cagcaactgg aactgtacca tcaactaatt caattttatt gaccttatta tcaaaactct 581760
catttgtata tactgtcgtt cctttgacat tatcaccaac ttggatcaaa gcatcaaagc 581820
gatttccata ttcaacctga gcgacttgct caattttttt aacagcttct atatcctcat 581880
ttgtaaatcc tagtgttgca acgtaattaa gatcattgaa agcgtgttct tgaagataac 581940
tatccatcgt tatttccata attgaagccg tatgccggag tcctgcaaaa aaggcagcac 582000
ctaaaaagac aatacaaaaa atcgacaaaa aacgtgcttt agtttttttt attatttgaa 582060
tttgattttt tacatatgct ctctttttca tattaccact caatttccgc gattgactta 582120
ggatgttcgt ttatattcat tgaagctact tgaccatttt taagatgaat gattcgatct 582180
gccattggag ctaaagcact attatgagta ataacaatta ctgtcattgt atatttatcg 582240
cacatctccc gtagtaatcc taaaatcgct ttaccggttt gataatctaa tgctcctgtc 582300
ggttcatcac ataaaagcag tttaggattt ttagcaattg ctcgcgcaat agccacccgc 582360
tgctgctcac cacctgataa ctgagccgga aaattatcta accgtttatt taatcctaca 582420
cgttccaaaa ccattctcac atctaaagga ttcttcgata tctgggtagc taattcaaca 582480
ttttctaaag ccgtcagatt ttgaaccaaa ttataaaatt gaaaaacaaa accaatgtca 582540
tctcgtcgat attgcgtcaa ctgtctttca ctatatttag caacatcttg accatcaact 582600
aaaatttgcc cacttgttgc tttatccatt ccccctaaaa gattcaaaat agttgttttt 582660
ccagcaccag aaggcccaac aattactaca aattcacctt tattaacttc aaaatcaaca 582720
ccatctgatg cattgatttc gacatcacca actttatatg tctttttaac attattaaat 582780
gtaatgaaac ttttcattta tcatcactac ctttctaatt aaaacatata cataattata 582840
tcacgaaact attctcaatc caatttctac ttttttaata aataaattaa ataatgctac 582900
tcatattaca agaattttca taaaaatcgt gctaaaatta aatcaattag gaggtctatt 582960
atgaaaataa tgattttatc agattctcat tctgtttcta aaaccgattt attaaccctt 583020
ttaaaaaaca actctgttaa ctattacatt cactgcggtg atatttatat gacttatgat 583080
ggcatcaatc ttaatagttt ttatttagtc cgtggtaata acgattttgg taatattcct 583140
gatgaattat ttattacaat cgatgattta aaattttata ttgtccatgg tcatcgctat 583200
gatgttgatt ataacctaga ttatttaacc catatcgcaa aagaaaaggg agctgatata 583260
gtttgtttcg ggcacactca tcgaccttat tacgattttc atgaaggaat cacttttatt 583320
aatcctggta gtgtttgtta tcctagaggt cagtatcgta atccaactta ttgtattttt 583380
gatactaaga caaaaaaaag tactttttat gatgtcacga cattagaacc atgtgaccct 583440
ttttccccaa tggaacgtcc taaaagaaaa gaaccatttt ataaaaaatg gttcaaataa 583500
tcggttccgg caaaactttt tggtacatga gcgtacaaat aatcatacaa actagcattg 583560
ggataatttg aatcaataac aatcccccca ctagataaaa attaatcaat cctaaactat 583620
acaatttaat taaaataatt atttgataca acaaaggaat aacaataatt aaaccataga 583680
agataatcat ttccaaatcg attatctttt ttaaatcttt tagatcatac cccatatgat 583740
acaagttaag aaagctcctt tttcgtcctt gcaattccat tcctacttta aaaatagttg 583800
taatcgataa caataccatg acactaaaat atgacatcaa cgtaaccata ctaatcaatg 583860
gggtatctaa agtataaata gttgtacaca tcaaaataat cgctgctatg gttattacta 583920
aaacaagcat tctaactttt tctagatcat agcgaacatt tcccagcgta attaataaac 583980
agcggtcttc taacgattca ttagtttgcc gattttcaat gaattcagga attatattct 584040
taactaggcc ataaacacca attattccaa taagagcaat caataaatga ctagctgtat 584100
cattaagaaa aggaaatacg atcattggta aaataaacaa aacaagatat attcgatttg 584160
atagtttctt tacgcctatt ccaaattttt caattttaac atttgcagtc accatcttat 584220
tgatgctggt acgataacaa tatcccatat ttaaaagcgt acaccagcca atttcacaaa 584280
ataaaatgat agcagttgcc ataaaagtat tactcgaaat ataatttaaa cttccttgat 584340
aatcaaagac cataaaaagt aaattattta ctaaaggaac tagaggataa ctaatgacaa 584400
aaccaattgg aatagctaaa aacatgataa tcgtactctg taaaagcaaa taaatcccaa 584460
cttgataaac agatgcccct gacatcaaaa caattgacac atctttagtt ttcgctaaaa 584520
cataaaaatc attagccata aatacacaaa ccattgcaat caaaattaca aaagcagcta 584580
tcgtagtaat caactttgca tcattcccac caagattgat ccctgtacta ggattaagtg 584640
taagattaaa gaataaaaaa ataaaaatcg ttgttaaaac aaaagataga aaataaaata 584700
aactctttaa aaaatcagtt tttaaagatc ttattgctaa ttttattaag cccattagtc 584760
aaacaacgct tgcgattctg tcgaattaat atcaacgatt ttgtaaaaat actctttttg 584820
actcatatct tttcgctcta ttgtttcatc aatcacacca tctttaatat ataataattt 584880
cgatgaatac gaagcaattt tagaatcatg agttaccatt aaaatagata caccgtcatt 584940
aatatttaaa tctctaaaca acgataacaa ttcatgagaa tttttactat caagatttcc 585000
agttggttca tcagctacaa taatctttgg attagtaact aaagcccgac aaattgctgc 585060
cctttgtctt tgtcccccag aacactcact tggatattta ttcaaaatct gctcgacatc 585120
taaccgtttt gcaatctttg caactgctgc ttttatctct acttttgatt ttcctgctaa 585180
cgtcagcggt acagcaatat tttcaaaaat cgttagtgaa tctaataaat taaattcttg 585240
aaaaataaat cctaaatttt catatctgaa tttaccaatt tctccctccg acatttgtcg 585300
tacctcttta ccattaatat aaacaaaacc tttagttgga atatcgattg ttgataaatt 585360
gttaataaaa gtcgatttac cagctcctga aggacccatg acacaaacaa attctccctc 585420
atacatttct aaagaaacat cacttaacgc agtatagggg ttttttgtcc ctacaccata 585480
tatttttgtt acatttttag caactaaaat tttattttcc atcatttttt cctccatgaa 585540
tcggtgctac caccgctttt ttataattat agtaagtaat taaacctgaa caaacaacag 585600
gaataaagta gaccccaatt actcctaacg caaaagcaac cgacatctcc ccatgataaa 585660
taaaacatcc tgaaataata attatataaa tcattggaat taataataaa actaaataaa 585720
aataaaatac ctcatactta attattttag ttatttcttt tcgtgtatac ccaatcttcc 585780
aaagattaaa aaataaagtt tttcttgtct gggcctccat acaaaattta taaacgatac 585840
tagttattaa caaaatgatt attacaatgt aaccaatcac tccagtaata tattcacgag 585900
gtgctccctg attagcagcg attgccgcaa tcatccctgt aacagaaatc atcattaaac 585960
taattagtaa aatagctcgc tgaattgaat aaccaaggtt agaaacataa atcaatgcat 586020
atctcttttc taataatttc ttttctttaa acttcttaat atactctggc agcgcatatc 586080
taatcaaacc aatagcccca acgatcccta ccccggtagg tgcgatataa gcggtagcac 586140
tatgctcatt cataaacatc ataactattc caaatacata taaaaataaa taaacagctg 586200
atggaattac taatttacgt ttatcactaa aatccattgc cttttcttgt tgtaacaaac 586260
ttgaaatatc atttcgataa atatacccac tagcaaaaac acaaagtgca actaggatca 586320
ttgcaactac aactatggtc tgcataaatg ctgctgaagg tatatgataa atcgatgcct 586380
caatccccaa ataatgaaac atccaataat ttgagattgg tgtaactgcc atccccaacg 586440
caagaccaat tggtgctgca atcagtaata atacaaatgt ctgataaatc aaatatttag 586500
tagatttaaa agaactgttt cccgataatg tcataatggc aatttcatta gtttttcgag 586560
aaataaaaaa gctatttgca aagaaaatca taaaacaaca aaagcaaatt atgataaaag 586620
ataatgttgt agaaagcggt acattgactt gattccatgt agtaccacca acgacagcac 586680
caggatcagc taataagtcg ttattcataa tattaaaaaa gataaagcaa actgcaatag 586740
caaaaaccat tgtcaaagca taaaaagcac tctttttata ctctttcacc agtaatgtca 586800
ttgcaaactt aaaatttccc atacttttct cctatctaag ttttaaaaac ttgattaatt 586860
ttattgatca atttaaaaaa attagtcatt tctgtttcat ctaaacattt agaaaataat 586920
tgcactaatt cctcttgtac ctttctagtc tgaactatca tatctttacc atgatctgtg 586980
attataacat tggttattcg tcgatcagat tcgcacgctt taaccttaac aagactacgg 587040
ccatgcattc gtgcaactat tcctactgtt gtagcatgtg agacatcaaa ttccatacta 587100
atatcttttt gattgatcgt tcgatcctga ttatcggcta aaaaaatcag gacactaagc 587160
tgtgtaaaag ttaatccata tggctttaaa cgagcatttg cataattagc aatatttcct 587220
gccagtttat ttaaactgaa cattacttca taatccttca tttccgcctc cctaatatgt 587280
agcctgctac atattaatat tataagatga ctaatattaa tagtcaatta aaatatgtag 587340
taagctacat attctaattg actaaaaaaa ctatacctta gtatagtttt aatattcatt 587400
cagctctttt ttcaaatctt caatatatct ttcttcaaat ttatctacac gaacaaattt 587460
tcctaatatc gattgaggtt caaaatcaaa atttagatac atgcgacatc caccatcagg 587520
caaaggggca aattgtccgc tccaatgacc acgataacta ttattttcaa catcatagtc 587580
aaattgaata ttttcacgta aatctgtaac aaaaatcttc gtttcccgct gttttcgatc 587640
atattcaata aatcgattat caccaatctg ctcaacccgt gttaaatcac tacgccatga 587700
acaatccttt aaattagtta ttactttaaa aactgctgct acttcacttt taaaatcaac 587760
tgtcatatct attcttttca ttttttgagc cctccacgat tccattataa cacaataaaa 587820
aaagagaaag cgaactttct ctaaataatt attttgctaa tgcttttttt gctgtattta 587880
caattgcagt aaatccttta ggatcacaaa ttgcgatttc agataacatt ttacggttaa 587940
cttcaacgtt agctaatttt aatccgtgca ttaattttga atatgagata tcatttaatc 588000
ttgcagcagc attgatacgt gcaatccata attttctcat atctcttttt acttgtcttc 588060
tatctctata tgaatatgct aatgaatgca taacttgttc atgagcagtt ttatataatg 588120
tatgttttga tccaaaatat cctttggcta attttaatac tttttttctt ctacgtcttg 588180
tagtaaatcc accttttact cttgccattt gtttcttcct cctatgtcaa taattatttt 588240
gctaatctag atttaattct cttgtagtct gatgcactta ctaaagtagc tttagctaag 588300
tgtttctttt gtttatgagt tttattgtga gataaatgtg atacataagc atggctgcgt 588360
tttaatttac cgctacctgt tctttttaaa cgttttttaa gaccactatg tgatttcatt 588420
tttggcatga tatattcctc ctaaattatt ttttctttgg tgcaattatt gcagttagag 588480
ttctaccttc tagcttagct ggtttttcaa tttgaccaac ttcagcacat tcagctacga 588540
agtcatcaat aacttttttc ccaagatcca tatgagctaa ttgtcttcct ctaaatctaa 588600
ttgcaatttt aactttgtta ccttcttcta accatttcaa tgttcttttt aattttacat 588660
ttttatcatg aacatcaata gttaccgata attgagtttc ctttaaagca accactttag 588720
aattacgttt catttcttta gctttctttt gttgttcgaa acgatattta ccaaagtcca 588780
taatacgaca tactggtggt ttaccgttag gggcaacaca cactaaatca agtcctgcac 588840
cataagcaat atcaattgcc tggttacgac ttttgacacc taattgatca ccattttgat 588900
caatgactag tacttctttg aaacgaattt tttcgtttac taactcatcc ggttgttttg 588960
gttttctgtt atcaaatctg ctaataaaag ccacctccat tttagtagtt taaacaaaaa 589020
gtgagcacac tgagtaccca cacattgaca ttaagatagt ttatcttagc gacatttgcc 589080
tatcgacata atcaatcagg cgagaagtag gcacttcttc tttccactac ttttcattta 589140
cttgagtata ttatcatttt atttaattaa agtcaaccca tatttaaaag atttattcat 589200
cttcatctat ttgtaaatat ttaaagtatc caaacaccga aaagactatc aatactatta 589260
atgcaaacat ttcatcacca ctaataatat atgtaatccc aataaaatta ttacttgttt 589320
ttatgattat gtttaaatac tttccattct acagcaatta tatttattaa taaatataaa 589380
cttagccaaa ttcttaatat tttcaatatc aagataccac catttatttc tcacttagcg 589440
accgcttgcc ccctagttct tcttgtgtca aattatactg cgcccacagc ctcttgctac 589500
tatagcatat cgactaaata gaagctagaa aatgccttgc tacttatcat aacaagacat 589560
tatttaaaca tttttttaaa ttcttctggt acaaccgctt taaattccat tctagctttt 589620
gtatccggat gaacaaaggc gaatacatga ctatgaagtc ccattcgttt aatcggatta 589680
gttgtagcac catacttttt atccccaaca atactatgac ctaatgattg catatggacc 589740
cgaatctgat ttttacgacc cgtttcaaga aatacttcaa tcaatgaatt atatcgtgat 589800
tcttttaata ctttataatt tgtaatcgcc aatttacctt taccattatt agcaatataa 589860
accatttgtg tcttactttc atcaaggtga tttttaatcg ttccatgctt ctttttaagc 589920
tttccttcaa taattgccaa ataaccacgc ttataaacaa tatcattcca attattttgt 589980
aatttatttt taattatttc atttttagca aacaacagta cccccgatgt ttctttatca 590040
agtcgatgaa caataaaaac acgggcattt ttatttttac ttttaagata ctctccaact 590100
aaatgataag ctgttttttc tttttcattt cctccggcca tacttaataa accagccggt 590160
ttattaataa cgatcagttc tctgtcttca taaataatat ctagacttga attattatta 590220
ggattacgat caacaacaat ctcatcatcc cgttttaatg aataatcaaa ctgactaatc 590280
acttgcccgt tgacagacac ctgcttaaat ttaagtaaat ttttaacatt ctttttatta 590340
tagtgattta ataaaaactc cattaacgta gaatctgtct tcactaaata cttattcatc 590400
gattttttcc gccttaactg ccattccaga aacttgacac tcaatcatat tgttgccaag 590460
gtttgttgtt gtaaagcgaa cattaatgat tgctgaagca tgtcttcgag aagcttgagc 590520
aactgtttct gccatcgctt cttgtcttgc tgtatctaac atttcttcaa tattagtatt 590580
atcactagca attgcctgat tcatgatttt actgctaaaa acgattccca gactctttgt 590640
aattcggtat ccgggtaaat aatcaatcgt acttacttca atcatatcca ttatattttc 590700
ctccttataa gaaaaggtta ctaaagtaac ctatttcata tcaatgattc gatgagtatt 590760
aaataataca actacaactt ctattaaata aattactaat gccagccacc aaggaataat 590820
aaataaaaca gctaagatca ttaagattac attaataaac aatcctacaa aaatattttc 590880
aatcgtaata tatttttgtt tcttagaaat catgaatgtt tcaataacgg tattaagatc 590940
agaattcatc agcataatat cactattttc aatcactttt ttatctttga tgccaccacg 591000
gctaatacct acataagctt tttgcaataa tgcaatatct tttgaattat caccaatata 591060
agcaactggt ccagcaatac ttgctttatc cattacttct aatttttcat caactgtcaa 591120
attattatag attcgatact gatcattttc aagatcaact ggtccatcat tgaaaataat 591180
caagccaaca tgtaattttg ataatttagc gaataattcc atttcctctt cagttacttc 591240
aactccatca aaacgatcat aaataactgt tcgacataaa ttcaaagcat ctaaaccact 591300
attttcttta ataacaatat ttttagaaaa agctttagcc actcctgata gaacagcaaa 591360
agaagaagcc tgcttgtaag caaaagaacc agaaattgtt attaaaatag cccctaaata 591420
aatatattta aaatttgctt caaaattaag aattggcact aatgttgcac aaagaattcc 591480
tgcgacgact aaaagaactg tatcaatctt actgattaat tctaccagcc tatgcgttct 591540
tgaagaacca acaggtgcca ttgtcgcaat ttctaagact ctgctcattg cactgcgatc 591600
atacgtatat aaaattttaa ttctcaaagt gtctttaaca ttgacacttc cactttgaac 591660
ttcacttccg gctttaactg gctctaaaat atctgatcca ttaatggcaa acatatctaa 591720
ttcactttca cccgaagcaa tcttgccacc tagaggtatc gtttctccag gtaaaactac 591780
gatcacatca ccaatatcaa aatcttctaa agaaaccatc tcatattcat tttcaccaat 591840
ttctcgacgt cccaattgaa ttgggttgat ctcgtcatca attttctcca tcgttaaatt 591900
gattaaacgc atcaataacc gttctccaac ttggtaaatc aaagaaacca cgatagcctc 591960
aatataagca ccataagccc atccaaataa acaagctaga ttaattgtaa tattttcact 592020
taagaattgt ttaactttta aatctttata tgcttgaacc aaggtctttt cattaaaaat 592080
aatcaaagca atcagccagg caatattagt tataaaatta ggatcatctt ttgtaactaa 592140
tccaagtgct aaagctacaa ataatcctgc aattctaatc attgtattta aatatttttg 592200
ttgaaaaata tcttgtgatt taaatggctt cttccattgc tccacatcaa ttttaggatt 592260
aactttatca actagacgat ttaatcgcac taaaatattc ttttgactag ttgtgacttt 592320
aagtaactta ttagtaaaat caagactaac attttcatag gctgaatatc gtgaaataac 592380
ttcctcaatt tcttttgcct cttcttctgt ctctaaatta gtaaacataa aaatatgttc 592440
tactttttgt tctggtgcca cgaattcacg cttacgtgag ttgatttcct cttttaaaac 592500
aagattttca tcatgattat tcaaaaccgc ctgcacattt tcaggatctt cacaataaaa 592560
tgaaatacct gtttttccaa tcttgattcg tgaaacttct tccatttcgt ttaagaggag 592620
gctgacctca tttaatttat cattatcatt tatattatca atatagaaat tacgagccat 592680
agtaatctcc tttccaatag tcacctaatt ttagcatatc ttcaaaaaaa ttccaactct 592740
actcattaac accataaact aactgtaaaa tttgaggata ataacgttca aattgcaatg 592800
catcaatttc cgttggataa gacattaaat gaaaatacag acgatgtttt aagttacgca 592860
caggtggtac aaaataatca tgctgatcat ttagcactaa gccatttctt tgataaaacg 592920
caatccgtcg acgactttgc tcatcttctg gatgttcaac ttccaaaata accggtttcc 592980
ctgccgtctc cataaaatgt tttaacatct tacttcccaa acctttgcct ttttgattac 593040
catctattgc aaaataatca acaaaagcaa attctccacc atcataatgt gataaaatac 593100
ctttaatttc atcatcttct tttaaagtca aaactttaaa atcaccatta ataaaagtct 593160
ctttcatata atcatattct ttgatttctt tactaggaaa atttcctaaa ataactttat 593220
aaaaatcatt aaattctgct aattttaaat cttcaaatat cattttctaa cccccgtttt 593280
tttatttatt aaaacaaagt tttcttcaaa ttcctcttta gtacatgaca aatcaaactc 593340
tttaccatat attttataat ttacctgaag ctgaccacta tcacgaatca cacaatcgta 593400
aacttggccc ttagtaaata gatcccgctg ttctttacca attacaatat tcattgtctt 593460
gatacaacga cacacgcgac gttttcctgt atttgcgata gtaatcacct cttttctcat 593520
tcattataac atgataatta aaagaaaagt aagaattagc cctgctaatt cttactgaat 593580
tccaataact ctaaatcagg attcttctct gtagcccaac gaacgcccca atcattagta 593640
aacaataata aatgttgtcc ttttaaatct tgtacttttt ttgtatcact agataaattt 593700
aaagctttta aatcgcatcc ctctttaacc cagcgcacat attgatatgg tagcggctgc 593760
ttgattatct caacattata ttcattcttt aagcgatatt ctaatacttc gaattgaagt 593820
accccaacga caccaacaat aatttcttcc attccaccgc ctaattcagt gaaaatttgg 593880
attgctccct ctttagcaat ttgttctaca cctttaacaa attgttttct tttcatcgta 593940
tctttattac gaatcaatga aaaatgttct ggagcaaagg taggaatacc ttcaaaagca 594000
aatttagctt tacctgttgt aatcgtatct ccaatcgaaa agatccctgg atcaaaaact 594060
ccgatgatat ctccagcata agcttcatca acttcttgac gttcatcagc catcaattgt 594120
tttgactgat tcaattttat tttacgacca ccttgatagt gatatacttc catcccttta 594180
gtaaatttac cagagcaaat tctaaagaaa gccattcgat cacgatgtgc tttattcata 594240
ttagcttgaa tcttaaaaac aaaggcactg aaatcttcac taaatggatc gattgttttt 594300
tcaccagtac ttcgtggtaa tggtggtgtt gtcatttcta agaaatgttt taaaaatggt 594360
tcgattccaa agttagtcaa agcagaacca aagcatactg gagaaagttt accttgacgc 594420
actttttcta aatcaaaatc atttcctgcc atatctaata actcaatatc ttcctgcagc 594480
ttattatata attcttcatc taattcatta attaattcag gatcatcata tttcattatt 594540
ttagtatcaa cttctttacg cccgccatca acagggataa aacggattac ttcctgatca 594600
tgccgttcat aaacaccttt aaactgtttt ccagaaccaa taggccagtt aactggacaa 594660
gtatcgatcc ccaattcttg ttcgatctct tccattaaat tatatggatc ttgagcttca 594720
cggtccattt tattgataaa agtaaaaatt gggatattac gcatcgtaca aactttaaat 594780
aatttacgag tttgatcttc gaccccttta cttgcatcaa taaccataac tgcacaatca 594840
gctgccatta atgtacgata agtatcttca gagaaatcct gatgacctgg tgtatctaaa 594900
atattaatac aaaaaccatc ataattaaat tgcaatacag atgatgttac agagattcct 594960
ctttgctttt ctatttccat ccagtcactt gttgcatgtc tgctgttctt ttttcctttt 595020
acggtacctg cctgttgaat tgcccctccg tataataaga atttttctgt taatgttgtc 595080
ttaccagcat cgggatggga gatgatggca aacgttcttc ttttttcaac ttctttgata 595140
aaatcgctca tttttatatc tccttgcaag gattaatcat atagatttat aatgaatttg 595200
tcaaccgaaa tctatttact cagactgttt aacggagtct tcgtaataat gaaagcaaag 595260
acagtgaaga ttacaaatcc accgattatc acaaacggat aaactattaa ttttcccgat 595320
tcaatcaata acggtaaaat tgctaaggca ccagctggcg gaaaatataa tttagtaatt 595380
ttcataatgc tcaacatgat cattacaatt ataattgcac taatagttaa tggcaaatca 595440
ccaatctcac ttatcaaaat tcttccataa gcaccactaa atgcacaaat aaaggtaaca 595500
aatgctaatt taatcgaatt atgacgcaac tttgggtgat tactactcaa ttcaacaaaa 595560
gcaactatca agggtggggc aatcaaaaac agtaatttta attgtaaagc aataaaagcc 595620
gttaatgcta atgcacataa ccgttttaaa tttaagctat aggtttcttt aactgctgca 595680
gtaaccggat gatattcctg aacactacga tagccgccct tctctaaata ttgttgcccg 595740
attacaatca aaatactcat tgcagtagca aaaagcggat acaaccatga ctcactatta 595800
ataatgattg gtaagatcgt tgcagatatc aatggagcaa acgtcgtttt agataaaaat 595860
aatcccgtca cacatactac aaagccaatt aaaattttaa aataaatatc aatatctaca 595920
tatttaacca aaataatccc taacgacgca taagccgcaa ttaaaaaaac caatttaatt 595980
ttattagttt tccatacttg tttaggcgct aaccatgctc caatcgtcaa tgccgtaatt 596040
tctggaaaaa taaattcttt ttcatgaaac acttctgaca tcaagatcat taaagctact 596100
agcaagatcg tcattatctg gggaacaata cttttcttta cttccatcat tttcacctca 596160
atagaactca ttctattaca aaaagcgagt atagtaaata agaaaacgat ataacctaac 596220
cgttatatcg tcatttctta aaatacaaaa tttccgtttt caaatatcct tactacttga 596280
ccatcttttg tttctcccac aattttcaaa tcactagtac caatcataaa atcaacatga 596340
gttaatgaat cattgactcc cttttccaac aattgttctt tagtcattgt taaaccacct 596400
tgaatacatt cactaaagcc ttttccaatt gctaaatgac atgaagcatt ttcatcaaat 596460
aaagtattat agaataatgt tttcatatta gaaattggcg aatcatatgg taccaaggca 596520
atttcaccca aataaagact accttcatca atactcaaca tctcttttaa aacctcttta 596580
cccatttttg catcaaaatc aataattcga ccatctttga attccatttt aaattcatcg 596640
atcaaattac cattataatt taatggcaga gaactataca caaccccatt agtcccatta 596700
cgatatggac ttgtaaaaat ctcctcggtt ggcatatttg gaaaaaaata ttgtccttta 596760
gtcgtataag aacccccacc agcaaatagg taaccctcat ttaaggtaac agttaggttt 596820
gttccaagcg aattagtata agtcaatgta tttaaattca atttatttaa atatgctact 596880
cgagcttcaa aacttttacg atgttcctgc caggcagtca aagggtcatc atctacgact 596940
ttaaccgctt taaaaatagc attccacaac gcctctactg cctcactatc agacatatca 597000
ggatatactt tatttgccca tttaattgaa ctgccagcaa caatgcacca tgtatttatc 597060
cccaaatcaa ggctatcata aaatggttta caagcagttg atacactttt tgaccacaat 597120
gcgatctttg caggatcgat tcctttaaaa ccttcaggat catcactaat aattgttaaa 597180
aaggcagcct ttttagcagc ataatcattt ctaaattctt taaaccacgt tggaacatga 597240
gcaaacgctt ctttttcaag atatttatat ttatatcgtg aaacaacttc atcattatat 597300
tttacaacca cttccctagc tccagccgca tatgcctcct tagttactaa acgtactaat 597360
tcaacactct caacaggtgc atcgattaca acaatttgag ctggctgaac atttaaacca 597420
gctttaacga tcaattgtgc atattttgat aatttttctt taaacgacat ctttatctac 597480
ctctttccat caatttatta taatcaatct aaacttcttt atacctcttt atcgagctta 597540
ttcaactctt caatcgcctc tttcattcct ttattggcag cctgcttaaa atactctttg 597600
gctttttgtt tatcttgatt aattccatct ccataactat acatatagcc aatcataaaa 597660
ctagcatcat aatacccacg ttcactagcc tttaaaaaca atttaaaagc tgaagcttta 597720
tcaactgttg ttccaatacc ataaaaataa caacgtgcta aattatatat tcccggtaca 597780
tattcatcac ttgttgaagc aagatagtat ttgaaagctt catctaaatt tttatatcca 597840
ccaattccat tttcaagata tattccatac atattcatag ctggtccata gccttgatta 597900
gcagcaatct gcaaataagt aaaagcttta tctagatttt tagcaattac tttaccttca 597960
tctaaatata aagccatccg atacatagct cggacatcat tttgatcaat tgcagcttca 598020
taatatttga ttgcctttaa atcatcatga tactgttcat tatgctcata gatcaaacct 598080
aaattataaa gggcaattcc ataatcttga tgacttgcta attcataata ctcaattgct 598140
ttatcaatat caacatccac tccattacct tcttcatatg ccaaagctag atgataaaga 598200
cccggagcat aattagcttc tgcagctttt tgatataact taaaagcttg atgatgatca 598260
acatccactc cttctccatg atcgtataag taacctaaat tacataaagc ccgcggataa 598320
cctgcatctc cagccaagcg ataatagcgg acagcttcat ttaagtcgac atctatacca 598380
attcccattt cataacaata tgctaaatta cattgggctg gagcataccc ttgattagct 598440
gctttattat atagttcaat tgctttgatt aaattttgtt taactccaaa accactttca 598500
taacagtaac ctagtgctac gattgcctga acatcatttt gtttacttgc ctgacgatac 598560
caatatgaac agcgatatgg tgcattttta atttcaggat gattctcata aaaataaccc 598620
aaccaaaact gtgctcgcga atatccttga cgtgcagctt ttaaataatt ttgacgtgca 598680
gcttttaaat caatatcagt tccttgacct aattcgtagc acgacgctaa cgcaattaaa 598740
gcaggagcgt aattaacttg actagcttga taataccaat aaaatgcttt aacaaaatct 598800
tgaattgttc ctaatccatt ttcataacaa taacccagac ggtgttgaga acgttcgtgc 598860
ccttggttcg cagcttcttc gtaacatttg aaagcacgtt caatatcttg ttcaattcct 598920
tcaccaaatt ctaaacaagt tcctaagcta tacaaagcct cactataccc tagtttagcc 598980
gcctgataat aataattaac agcacgtgga agatcaacag cagttccatg accgtattcg 599040
taacaatagc ctaaattaca aatagcacga gcaaatccag ctcgagcccc aaattcatat 599100
aactcaaaag ctttctgata atcttgtttc acaccgattc ctaactcata gaaatatgct 599160
aaattgcagc ttgcgacaac atttcctaaa cttgttgctg attgataata acgaaaagcc 599220
tgataatgat cttgttcgac acctagtcca cgttcatata aataaccaat aatgcaaaca 599280
caatcactat tatccacctc tgctcccttt ttaaaatact ctaaagcttc aagatattca 599340
tgtttatcaa ataatttcaa acctaattca tacaataatt taccactgac attatttata 599400
ttttgtaaac gatcaacttc atcaaccatc aaaagacata ggtcaatacc aattatcttt 599460
ccttgattat cctcaataag atattgttca taatctaaat attcactttc attgattact 599520
tgcaatccta atctattttt aatctcttct acacgttttt ctaaaaattc aatattatta 599580
tcttgatcat ataatgttat tacttttaaa agagccgttt tctcaacacc aatcgcttga 599640
tgtttaattt ttatcaatga ttcttgatca tgaatttcta ccagttcttc aaacaaccat 599700
tgattaaata acggctcata acttttaaca cgatctttta tatccatact tacctccttt 599760
cgatagagaa ataagcagat attgttatct gcttactgtc cattaatcat atgagatatc 599820
tcttttgaat actttcctaa aattgcacta accttgttac ttgtttgaac gattccagaa 599880
gcaccaagtg cttttaactt atctaaatca accaaactat catcatttac aaagaaagtg 599940
acttttgaag aagtagctgt tgtttcttta atattcgtct taccgccgac agcttcgata 600000
atactattta catcaactgg aatatcagca gctgatactt gctttggttg cttatttttc 600060
attactttta ggaaaataaa cgctaatatt acgattacaa tcagtgcgat tattccatat 600120
aataaatatt cattcattaa aatatacccc ctattaatta ccatttaatt atagtatact 600180
ataccatgat agaaaaaact atcattttta taaggaggga ttttgtggaa gaaaaagaaa 600240
aatccgttat ctgttggcca ttaatcggtc tattactatt gctttgtttc attagctgtc 600300
tgggaattaa aagcgccact cctttgatta ctaaaggaaa tccaagtggc tattggatta 600360
aacagctaat gttttatgga atatcattta tcttgatgtt tatcgtttat aaagtctcca 600420
acgatcgaat ctattcatcg atgtggatca tttatggaat tttaatggtt ttactagttg 600480
gtcttgctat tgatcacttt gcatttacgc gatttggaat acatattgtt cctttagcta 600540
aatgggcggg tggtgccaca tcctggtaca atctcaaagt atttgatctc cagccatcag 600600
agtttatgaa aatcatcatg gtggttgtca tggcagatac agtcgataaa cataataatc 600660
gctatttagt acataatatt cataatgatt gtttattgat tggtaagctc ttagctattt 600720
ccttaccacc ttgtatcctc gtttatttac aaaatgatgc cggagtaaca atgatcatgc 600780
ttgcatcagt agtattcgtt atttttatgt ccggtattca agccggctgg tttatcatag 600840
gggggattgt agttgcaatc atccttggga ttggagttta tctattctta taccaacatg 600900
atatttttgc tagtttaatg ggaggagacc ataaattaaa tcgtttctat ggctgggtcg 600960
atcccgaggg tacctataat gatcaaggtt tccaactgtt taatgcaatg ttatcatatg 601020
gaactgccgg cctatgggga catggtatgg gaacagctat cattaatctt cctgaggcac 601080
aaacagactt tattttcgct gttattgcct taggatttgg atttgtcggt ggcggtttca 601140
ctattgcagt tgtctgtgta cttgatgcct tattaattag aattggtttt aaatctaaaa 601200
ataatcggga taaatatctc acagccggaa tctttggtct acttatcttc cagcaagttt 601260
ggaatatcgg aatggtttta ggactatttc caattactgg aatcacctta ccatttctat 601320
cctacggtgg ttcatcactt ctttcatata tgattgcaat gggaattttc ttagatatgg 601380
aacgacaaac gcgaatcctc gaaggaaaaa agcgctatta acttattaat tatataagat 601440
gatttattaa atgataaatc atctttttat ttcgataaaa aagattcctt catttaattt 601500
cagctatttg ctatccattt atgaggaatc attttaattc ttttcaaatt gttttgaatc 601560
tttctttact tcaatcagac gttgtgtaaa agggtcaata aaacttaatg ctatactatc 601620
caaatagtaa gattcttgat aaatcgaatc ataaagtgta tccccaacta acggatgatt 601680
gatactagat aggtgaaccc taatttgatg agttcttcct gtttctaaga tacactctat 601740
tttactctga ttagcactta cctccagtcc ccgataatgg gttacagcaa atttcccagc 601800
tggatgaatc agtcttttaa cacttttttt atctttaata attggcgctg taatcgttcc 601860
ttgtcccgtc aatactccct ctactacaca gtgatagaca cggcgtacct gcttgatatc 601920
tctagacaat aaataatgag cataactgtt tttagctatc aacaataatc cttgggtatc 601980
tttatccaat cgattaacca aatgaacagt tgcctttatt ccctggcttt gatagtaata 602040
aacaactgca ttggctaaag tatttcgagg ataacgcttt gtaggaatac ttggtaatcc 602100
tgccggctta tcaattacta aaaaattttc atcttcatag caaattttta aagctagcgg 602160
atatggttcc atagtactaa cttcttcagg ccacaataat tcaacaacat caccgtaccg 602220
caaacaatat cgtaccgttt gacgctgacc attaacaaga atcttcccat gcattttaat 602280
taatttaaca gcttttttac taagctcctg ttgactaaga aattctctta acaacattcc 602340
gctttctttc attgcgataa taaatttcat tcgctgataa aagcccttct aattcgttga 602400
ataaaagaca tttccttata ttctatgaac tttactactt tcttagaaat tctaatttca 602460
attttttcaa catcatcaag atgataagat aagtgatcaa ttcccaaata aactcgatta 602520
aaatgctgtc cttttaactt aatcacctta ttttcatcta aaattaaact agcacccaaa 602580
cttcgataag cattatgttg tatagcggcg acttctgtca gttgcattaa gggatttcct 602640
ggataaataa cagctccacc aattgactta ttataagccg tcgatcctga tggtgtagaa 602700
acacaaagac catttcctct aaatacttcc aaaagctcat catcaatata gacatcaatt 602760
acttgagttg tatacccatg atcaatgcgc atctcattta atgctaaata tgtttcttta 602820
cctgctttat gatacacatc aacttctaat aaatgtcggg gcgtcatttg ataatgatca 602880
gcttttatag ccgcaatcaa ttcagtaatt tcatcttttt gataatctgt aaaaaaacca 602940
agggttcccg tatgaacacc tacaaaacta actttttgct ccatatattg atgcactgac 603000
aaaagcattg ttccatcacc accaacacta ataaccaaat caggatcatc gggattatat 603060
tccataattc cggttaaccc tttcttaatt ttttcagcaa tattagcaga catttcatcc 603120
tgttttacta ctaatgcata ttgtttcatt gttttcacca accttagcgt atatactata 603180
gtatatacta atggaggcta ctatggaaga aaacttagaa atagaattta aagtattgat 603240
cgacaaagaa atataccagc aaatctataa cgatcaccac atcgaccatc aatatagtca 603300
aactaattac tatttgattc accctaaatt aactgaatta aaatatatgc tgcgaatccg 603360
tcaaaaacaa gagaattatg aattaacctt aaagcaacca caatcatatg gaaatttaga 603420
aactaatcta aagattgaca aaataactaa agagaaaatc attactcacg attttgttac 603480
taatgaaatt tttgaccttc taaaacccct tggattagat agtacgatgt ttaaaacaga 603540
ctgtgtactt actactacac gttgtgaaat taagactact gatggcttga tttgtctaga 603600
tcaaagtctt tataacggaa ttactgatta tgaattagaa tacgaagtat ttgattatca 603660
tcatggtaaa caaatatttt tagactttat tggtcaatat aatttaaagt attctcgtaa 603720
ttgtcctagc aaggtaaaac gtttaatgga tagtttaaaa gatgattaaa taatcatctt 603780
ttttactaga actaaaaaag cagcgtttca taacactgct atctatcttt aaaataagcc 603840
tctttaattg agcatggttc actaataaat tgtggacaaa cttcactact tggacattct 603900
gctaatttac gtaactcacg aggaataaat acccggattt cctctgcatt ataacctacc 603960
tggaatcttc gctcatcaat cataattggg cgttttaaaa ctgatggatt ttcttgaata 604020
aacttgatca gctcactaat tgacatgcta tcaatgtcaa tatcattttc cttaatgatt 604080
ttacttcgct tagaaatgat atcgtctgtt ccattttcgc ttcgttccaa tagttctttt 604140
aattcaattt ctctaagcaa ggttgaaaaa atattttttt ccacataagg aatattatgt 604200
tctttcagcc aagacttaac ctttcgacat gatgcacaac tcggtgctgt gtaaatacga 604260
atcataatac catctccctt acttcactat tatacattat ttttattatt tttctatcat 604320
tttcgttaat catagtaaaa taatatgcaa atcgaggaac ttggattaat caagttcctc 604380
gatcatttta attacctcta tttttgaaaa acctagtttc ctcatttctt caataaaaac 604440
tttaacttta tcaagtgaaa catctttttt taattcactg atcaaattac tgtcttcact 604500
gacaaaacgt cctaaagctc gcctgctata aattattccc gttctttcta attcacttaa 604560
agctttttga attgtattgg gattaactcc atattccaac gctagctctc ttactgaagc 604620
aagcttactt cccggtaaat actcactggc aaaaatctct ttttttattt cttccatgac 604680
ctgaatataa attggtaaat taggatcgaa gtcatttttc attctaccac ctactctact 604740
tcaattttat gatcaattaa ataaacagtg aagaaataaa atgctgttgc taatactaaa 604800
tttaaaacaa tgctaaacca aacagaagca gtactatcca aactcattac aaagctctca 604860
attggctgcc acattaataa gctgcttcct aaaattaaaa gtgctacata aacaataatt 604920
ccaataacag ttttgtgttt aggaatatat ttagtctttg ttaatgtaat aatagcataa 604980
aatgataata tcattgaact aaccatcgca attgaatcaa ttaaatttat tactactaaa 605040
ccaaaattat tacctaaagc ctttaacaac tcaccaaata aatcaaataa agtattcaaa 605100
ggaacattac caattaaaaa tacaataatt aatattccca gtgataaaac aatcgaacta 605160
acaaacaccc aaattaaact acctataaat ttagccccaa ccaatttttc agtacttaca 605220
ggcaacgtca aggttaaata accaggtcgc ttatacattg aacgattaaa atttgtaata 605280
acattgacca aaactgcaat tgatatacct aacattgcaa aaatcatcaa tgaactcaat 605340
acttgactaa taaaatctgg caacaacggt gccaaaacac ataaaatcaa aaatattcct 605400
aaagttaaaa agtattgacg atacgattga atcatctcat attttaataa ttttaacatc 605460
taaatacctc cctaaaggct tcatcaattg actgttttct ttctaatctt aaatcttctg 605520
ttgattgatg caaaacgatt tcaccatctt ttaaaaacac gacatcatca aaaatagttt 605580
ccaaatcact gattaaatgt gttgaaataa gtaccagagc atcttcttca taattattca 605640
aaataacatc tagaataact tcacgagcag ctggatcaac accagctatc ggttcatcaa 605700
gaatatataa tttagctttg cgtgacatca ccaatgatag ttggaatttt tctttcattc 605760
ctttagacat ctctttaatt ttcattccct tatctaattt aaaacgattc atcagagtca 605820
aacaattttc tttatcaaaa tcttcatata aatcactgaa aatacttaag acatctttaa 605880
tatacatcca atcttgaaaa taattctcat ccggtaaata tgaaataatt tttcgtgaat 605940
caattcctac atttttccca tcgactaata cttcaccttc ataatctttc aataacccat 606000
taataatttt aatcaatgtt gtttttcctg atccattagg acctaataaa ccaattattt 606060
taccagattc taatgtcatc gaaacattgt ttaaagcctt aaaatgatga tattttttgg 606120
ttacattagt aatctttaat agttcactca taactctcct cctactgtat taatacacta 606180
atacagtaac acgaatttat agtattgtca atacaattat tcttatgact caaaacaaaa 606240
taaaaagatt tttctagtta tttacataga aaaatctttt tatttatttt ttcacaaatt 606300
cattataaag aagttcatga ataaaagaat atcccttttc taattttttc tttagatgaa 606360
gatatttacc aatactttta tcatcattga tttccaactg tttacaaaca tttagaaatt 606420
tatcatagtc ttcaacatat aattgatcaa ccatgttttc aacatattgt tttttaattc 606480
gttcattgcg tgttaagcca tattctttga ttaaaccctc atcatacatg tgataattga 606540
tctttactat cggtaatttt tttaattcat gattaattaa tgttcgctgt ttcatcatcg 606600
ttaatgaacg ataaactaat ttaccattat tatttatttc tacgactaca ctatatttcc 606660
catcaccaac aataaagatg ttattaaaat attgactatc ataaatattg atacagccat 606720
aaataaaatc atgcaaagtc ttctcatcaa catgataaat atctactctt gaaatgattt 606780
ctagatcatc atcttcatcc cattcatatg gttctaataa ttcttcatct tctttaaccc 606840
agtttacaat tatatctttc atatcttcct cccatataaa tatatgatta ttttataaaa 606900
tcatgttttt agtatatttt tatttttaat taatatataa tgattcctga ggtgaaaaca 606960
tggaattaat taaaaatatc atcatttatg gtattcttgg agcgattcaa ggttttagtg 607020
aaccaattcc catatcaagt agcggccatt tagttatttt tcaaagtatt tttgaaaaaa 607080
tgggactaat ggttcctcaa atgaacgatg ttacttttga agtaatcgtc aatactggat 607140
cactactcgc gatcatgtat tattatcgcc acgatattgt tagattattc acagctttct 607200
ttggctatat tcgaaaacca aaaaaaagaa actattacga aggtgatttt agatactgta 607260
ttttattgat tgttgcaact attccggcag caattggagg atatttattt aatgataaaa 607320
ttgaagcagc tttttctaac cctaaattag ttggatgcat gttactggtt acagcgattt 607380
tcttattatc aatccataaa tttggctaca aaggaaaacg gacagcaaaa aaattaaact 607440
tattcgacgc tttaagaatg gggatttttc agttatttgc attacttcca ggaatctctc 607500
gtagtggttc taccctaaca ggaggaatgt tagggggatt atcacaaaag gcagctcgtg 607560
atttttcatt ttttatgttc atgcctgtta gttttggagc aattatttta aaactaaaag 607620
actttttaac atccagcaca cttggtgctt tatggcttcc ttatttagtt gcttttatta 607680
taagtggaat cgttacatat ttggctctac acttattatt taaattacta gataaaaaga 607740
aattaaatgt cttttcttta tattgtttag tagttggtat tttagccgta ttatttttgt 607800
aaaacagttt aaaatgaaat gtctctccat taaagttcat ttcaaaaaac tgtttttttt 607860
actattaatt ttaattatat ctgtaatatt catttcttta ccatcaattt tgattatttt 607920
tttgtataga tcaaaggctg taagtatatc cttgagaatt gcataattat cttgagcata 607980
ataagcagtt tcgatcattt attcacttct aagctaccta atcttccagt ccaactcttc 608040
tattgcatca agagcaagct ttttcgttcg ataatgaccc acaatttagc cctgaacaat 608100
tctttaaatc cttttagtgg atcataagat aaaattattt tacacgttcg gccttttcat 608160
cacattgaac tattctcttt ccaacatgct aaaaaccagt taatagctga tgatgaagtt 608220
acaataaaaa aataccattg atttacttta atcacaagta attcgatggt tattgataaa 608280
tactttgatc ctcaccaaat cctagaatta ccaataaaga taattggcaa agttattttt 608340
actaaaaact attattaagt aagaattcca tctctcactt tttaatttga acaattgcac 608400
aagctccatt ttcgttattt aataatttta gaataccgcc atgtttttca caaaggatct 608460
tactaatcga taatccaatt ccaaaacttc ctttattagt ctgtgatgaa taaaataatg 608520
tagttgcatt ttctaaatcc tttttactaa aacccggccc atcatcctga ataacaaatt 608580
caagataacc cacagtttcc ataatcgtta acttaacccc attattagca aagcggaaag 608640
cgttatttaa caaattttct aatattttaa aaataatctg tttatcaaga tataattgtt 608700
tagacactat ttttgcttct aatactaaat ctttatgatt attcttagcg ataatcataa 608760
aatcattatt aatttcttct agaaaatctt tgccgacaac cattgtctta ctaatttcaa 608820
tatcttctat tttttggata tcttgaatac attcaacata tcgctctaaa cgagctgatg 608880
aatgagccat actttttaag gtcgttaata aaacatcatc agatactctc ttttctggaa 608940
gattttttaa taaataatca aggtatccct tcaatactgt aatcggggtt cttaaatcat 609000
gtgatactga tgccgttaaa gcttttcgct gatctaaaag ttcccatact ttttggttat 609060
tttcaatcag ttcattacgc attacctcta aagtactaca taaccgacct aattcatcat 609120
tagaattata agttatttga aaatcaagat tattattggt taaattagcg attcctatat 609180
ttaattgttc aatcggcaac gccagtttta aacgatagta tatctttaca ataaagattg 609240
tccctaaaac aagatataat gttggtaatg cgatcatcgc tactgtcgca ctaagataaa 609300
taaatttatc ttgattagcc aattcactat actgatactc atcatttgag ggcgagattt 609360
catacgtacc tgtaatattt tcactaataa tagcggtatc tactgcaata tgaatagtcc 609420
gattatcaag aatcatttgt cgtaatgatg aagtcaacaa aactgttgta gaagacaaaa 609480
taataattaa aaataaagct acacttaata ttaataataa tgattttttt aaagacatgt 609540
tataaaattg ctgttttatt ttttccatcg ataccctacg ccccacactg tttctaagta 609600
ttcattttca ctataccggg ataatttcat tcggatttta cgaatatgtt ctttaattac 609660
agcactatca ccattagctt caaagcccca tactacttca taaatttttt cacgatcaaa 609720
tatttgacca gcattcatag ataataattt aataatttca aactccttat tagaaaaatc 609780
aattttttta tttttaataa ttacggttct ttgactataa tcaataatca gttccctagt 609840
aaaatgtcct cgtgatttat gggagctgcg tttttcacga cgtaaatgag cttgaactct 609900
tgcgaaaagt tcatccatcg aaaatggttt tgtaatataa tcatcgcctc ccagcattaa 609960
accattgatc atatcccgac tagaaattcg tgctgttaaa aatataatcg ggcaattcac 610020
atgttcccga atcatcgtac ataattctaa accattcatc tccggcatat tgatatctaa 610080
taaaataagg tcaggtaaaa ctgataattg ttttaaagct tcattagcat cattagctaa 610140
ataaactaaa tatccttcag attgaaattg taatgccagc atttctaaaa tgtctctttc 610200
atcatcaatc ataagaatct tatacattgt tttttccccc tatagttatt tttattatac 610260
ttaagtttgt caatttttgg tcaacttcat aaaaaaactt aagtattatg catcaacctg 610320
caatcgttag atttttaagg ttcaatacaa taacttaagc tcttttataa ttatttagtt 610380
gcaataactt ctacttcaat taaagcccct ttaggtaatt tagctacttc tacagcacta 610440
cgagctggga atggttcaac aaaatattga gcataaatgt catttacagt aacaaaatca 610500
tccatattat ctaaaaatac agttgtttta ataacatttg caaatgttaa accttggctt 610560
tctaataatc cttgaacatt ctttaatgat tgatgagctt gtgcttcaat tccttcaggc 610620
atttcccctg tttctggtac taatggaatt tgtcctgaaa agaaatacat atcaccaaca 610680
ttaattccct ggctatatgg tccgatagct ccaggtgctt tatctgtttt tactacattt 610740
ttcatcttta atatcctcct taaatcatta taaacaaata atcactattt ttaaagtttt 610800
attaattaaa atattgctat ttttatcact gtgataattt attattgact tattacaatt 610860
ctttgctata atgttgacaa tacaaaagga ggatagcacg actatgaaat atacatttgc 610920
agctagattt aataacatta ctccaagtgg tattcgcgct gtactagaaa aagcagcggg 610980
acccgatatg atcaacttct caccgggctt tcctgataac gatgcttttc cagctaatga 611040
tattcaaaag atttcacaag atgttcttaa ggaagatatt tatactatct tgcaatattc 611100
cagaggtacc acttatccac cattaaaaaa ggcattaaaa gctttcttta atcgtcaaga 611160
aaaaattttt acagaaaatg atgatctaat ggttacttcc ggctcaggag aaggactgga 611220
aatggctgcc aaagtatttt taaacccagg agaaagtatc attgtcgaag atcctacatt 611280
tgtcggagcg ctgaatggat ttattagcaa tgatgctaaa ctgcttggtg tgcctgttga 611340
aagtgatgga atgaatttag gattattaga agaagcaatg caaagcactc ctgcccccaa 611400
actactatat attattccta ctttccaaaa tcctacctgt atcactactt cactagaaaa 611460
aagaagagct atatatgact tatgtttaaa gtataatatc atcattcttg aagataatcc 611520
atatggcaca ttgcgtttta aaggtaaaac catcccgact ttaaaatcaa tcgatactga 611580
aggaatcgtt gtttactgtg caagcctatc aaaaatcatt tctccgggta tccggcttgg 611640
aacaataatt gcgaataaag aaattattga taaatttaat attcttaaag gggctagtgc 611700
tggagccgta actaattggt cacaacatgt aattgcacgc tttttagaaa cagttgatat 611760
ggataagcat cttgctcatt tacaatctgt atatggcaag aaaagtacat ttatggttga 611820
aatgatgaaa aaaacttttc atcctgatgt aaaattcact accccagaag gtggtatgtt 611880
cgtatggttt gaacttccaa aatatgctga tgctaggact tttttgaata gagctaccac 611940
tatgcatatc gcaattgtaa atgaggaaac ttttgccgtt aacagacgtg ataaaatgaa 612000
tggttttaga ttatctttta ctagtgcaac aatggagcaa atagaaacag gtattgctaa 612060
gttaggtaaa ctaacatatg aattatgtaa ataaatccac tgattggtgg atttttattt 612120
gttcgcgcgt ataattgaaa tgaggtgact aaaaatgaaa cgtggattag ttttagcagg 612180
cggaggttct aagggagctt atcaagccgg ctgtattaaa gcattaaaag aattgggcta 612240
tgattttgat ctagtaaccg gaacttcgat tggagctctc aatggcctat tagtcgttca 612300
agaagattat aacactcttt atcgattatg ggatgaaatc acaattagtg aagttttaga 612360
ggatcctgtc aattttaatt tttcaattga ctcaatgctt tcacaaacca atttaatcaa 612420
accttttttt aaatcatata tcaatgaaaa aggtgctgat atcactcctt taaaaaacat 612480
tctccatgct ctttataatg aagaaaaagc ctttaataat aaaatagatt atggtgttgt 612540
agctgtaaaa tatcctaaat tgactcctat cgaaataact aaagaagaaa tgaagcctgt 612600
accagccatt gaatatgcaa ttgcttcagc ttcatgtttt cccgcttttc cagtgcatca 612660
tattgataaa caaggttata tcgatggtgg ttattatgat aatcttccta tttcgctagc 612720
gttaaaaatg ggtgctgata aaattattgc aattgaatta aatcaagatg ctactcatga 612780
ttatttcctc gatcgtcctg atatcatatt tattcgtcct agctatgatc ttggcggatt 612840
tcttgatttt ggtcgcgaaa ttcttgattg gcggattaaa cttggctatc acgatacttt 612900
aaaaaaattt aaccagctaa aaggctatcg ttataacttt aaaaattttg aaatcaatca 612960
cgaattagcc cataaattct atcgtttaat tttaaactat gaagatagca taaataaaaa 613020
tgttgttagt aaaacaatta ccagcagttc aactcccttg agtgatctgc taaagaataa 613080
tacttattta aaggaactaa caaccgaaga ttactttgtt cgagcggttg aaatcactat 613140
ggatcattat cactatcaaa gtgatcttct ttatgatcta aatgaagtgt gtcacgaaat 613200
atttaacact tttaaagaag aatatcagga acgctatgat attttagaaa aacggtttgt 613260
cgacatacct attaaagaac tcttctccaa aataaaaaaa ttaagcagta aagatgctat 613320
ttgtgctttt tatcactcat taaataataa cgaagaaatc gaaacaactt taattagtaa 613380
tattttttta gaagaatatt taatcgcttt actactatat acgcttgtat aattaactaa 613440
agtttgctag aatcctccta ggaggaatta gtttgaatct caaagtaaaa aacatgatat 613500
attgttcaat gtttgcatgt atcactgcaa tcttggcaca aattcgattt accttaccaa 613560
gtctagtccc aatcacttta caaacactcg ggatttattt aattggtctg gtgttaaaac 613620
ctaaaatagc tttcattagt tccttgatat atattttaat gggagccatc ggcctgcctg 613680
tctatagcgg ctttagtgcc ggtttaagta ctatattagg accaactggt ggctatatat 613740
ttagttttcc aattacagct ttaataatca gttaccttgt ccattatcga agtaccacta 613800
tttttaagtt tggcgcttta atactcggaa caataatttg ttatttaatt ggaactttat 613860
ggtttatgta tataatgaag atgagtttta gtgcttcatt aattatttgc gtcctgcctt 613920
ttttacctgg tgatgtactt aaaatcttta ttgcagcagc cttaacaaat aaatttaaga 613980
atataataaa agattaggga atttgctttc ctaatctttt tttcatttta tgcttttgtt 614040
tcttttccta aacgtttata cgtttgataa aataatgtgg ctgtaacact aactgcaatc 614100
gtatcagcga ttggctctgc taaaaatact gcaaatgctt gattttctat aaacattggt 614160
aaaataaaaa tcaatggtat taaaactaaa acctttctta gaacggctaa aaatactgat 614220
gttttagcat ttccaatagc aatgaaagtt tgttgacaag caatctgaat tccaaaaatt 614280
cctgaagcgg ccatataaat acgaatcgcc caacgtgtat acgtcgccag ttctccatga 614340
cttgtgaaaa tataaataaa agtatctggt ataaacatcg ctactgccca taagagcatt 614400
gaataagata atgagatttt taataaaagt ttaaaagcgc gctttactcg atcaatattt 614460
tcagcaccat aattaaaact aataattggc tgagctcctt gagtaagccc ttgtaacggt 614520
aacattgaaa actgcatcac gctagtcaaa atagtcattg aacctaccgc gatatctcca 614580
ccatatttta ataatgaagt attaaaacat actgagatga cactttctgt aaactgcata 614640
ataaacggtg atagccctaa tgctaaacat ggtaagatga cttgaaaatc taattttaaa 614700
ttatctaatt ttattcttaa gccgctacgc ttacttgtta aaaaataaac aacaaagata 614760
gaagatatcg cttgagaaat aatagttgct aaagcagcac cctttacccc cattgacata 614820
ctaaaaataa aaattggatc aagcacaata ttgcataaag ctccaattgc aactgtaatc 614880
atcccaatct tagcataccc ttgagcatta ataaacgcat ttaaccccaa agccaattga 614940
acaaaaattg tacctaaggc ataaattctc atataatcaa gcgcataacc aatagttgct 615000
tcactagctc caaagaccat taaaatcggt tcaccccaga ttaaaaaaac agctgtcaag 615060
ataattgcca taattactaa catcacagta cagttaccaa gaatcttttc agcttttggg 615120
tgttcaccac ggcctaacat gattgatgct cggggagcac ctcccatact aactaaagcg 615180
gcaaatgctg aaatagccat aataacaggc attgttactc caacccccgt taatgcacta 615240
ggccctactt tggggatatg tccaatatac atgcggtcaa ccatattata taacacattt 615300
attatttgtg ctaaaatagc gggtaaagct aattttaata ataatggacc taagctatct 615360
ttacctaaat cagcctcttt tttctttttc actttaatta ctcccttcat ctattttaaa 615420
tatccaatga gtaattataa caaatttcaa agataattca attctttaaa agattatcta 615480
atttacatca ttttaaatac tcattcatat atcaacacat tgatatatat ttttttcaat 615540
tattaaaaaa cttggcagaa ttatcatttc ttttttattc atattctctt tgataataat 615600
aatatttgta taacttgttg aattaagcta ttttggctta atcaacaaaa aatcatactt 615660
ataatttata agaaatcatt gatttatgaa atttgctaaa cattataaat cttattcata 615720
attttgtttc aataaaaaga tgataaaaaa taagaaccat ggggtaatgg ttcttatttc 615780
tttacatctc taaatgagat tacttctatt tcattatcac gaagccactg ttttaacttt 615840
tcacttgtta cgagtgaata atcatataat ctttctttta acatcgaaga agtagtcgcc 615900
acatcataat caataaaacc aggatgtgtt actaaaatat tcaaaccttc tttaatttga 615960
taataaccat caatgaacat attttcaaag tcatgatcat gttcttcata ataatcatat 616020
tgtttcattg tctgatcaat aatcccctgc tccaagtcca ttccgtaata acatactgga 616080
acattatatt catgataaat tcttaccact gcattaatca atggttctac ttctaaaacg 616140
tgtaaatcaa tgtactcagg caattggcca actaattcaa tatatttttc aatttgatac 616200
ttagcttcga tgtaagcatc ttcctcacta aataatggtt cattattttt tatttgtgct 616260
cgacgaatcg tactcgataa aaatatcccg tgttcatcaa ctagactagg aatcatctct 616320
tttggtgcta atgcatatcc attagttaca ttaacatgta atcctaaaca cagatttgga 616380
cactgctttg ctaatttaat tgcttctttt gcatacggca tattaaccat caaagcaaca 616440
ctatttacca atccctttcg atgtgctgaa atcatcccca atgtcactgc ttcgctatat 616500
cctaaatcat caccacgtat caataactgc tttaccataa ttatcctctt ttctatattt 616560
tatataatta tactatacca aataaatagt ctatacaatt tattttttca tattcatgaa 616620
acatttatga tagtgcttat atttgcggta taataaaaga taactaaggg aggacaacac 616680
actatatgaa agatcgtttt agtttatcat ttaaagcttt ttatttaatc tatttgggcg 616740
cgattggctc ttttattccc tacattaata cttatttaga aaaaaatgcc ggcttaagcg 616800
gttcacaaat tggcttaatt acagccatca gtcttgtttt aggggtatgc gtgattccta 616860
tttggggggt cgttggtgat aagaccagaa aatatagtgc actattaaag ttatcaatta 616920
tggctgcact agtagtactt tacttctatt ataaagccgc tgtttatcct gctatcgtag 616980
tttgtgcaat cgcacttgaa gtatcacgac taggaacaat gccgatggcc gacacgctgg 617040
caactaatta ctgccataaa actggtggta actatggttc tattagagga atgggctcat 617100
tagggtatat gctggcagga atggctgtag gatttttagc tgatcttttt ggtcttgatg 617160
gagcaatgtt tgcaacatat gccgttttat taatcttggc tttctcgatt tccttcggct 617220
ttcctaaaga tgatggaaag aaagaagatg gtgaagaagt taaagtaaaa aaagggagtt 617280
ttaaagaact tctaactaat aaaaacttct tatttattct atttttacaa ctattaatgt 617340
caacagttgt cgattctgct atgacatatg gcggaaatca cttaactgtt actttaaata 617400
gtggtgcctc agcaataagc tggatgactt ttgcaacagt tttacccgaa gttgcattct 617460
tgatgattgc aatcaaagtt cttaataaaa ccggctttaa aaaattctat ttgattgcct 617520
gtgtatcaat gatgcttcgc tttggggtat atgcttttat tcccaatcaa tatgcttttt 617580
tagcaataag catcgtacat tgcatcggcg ttgccatcgc aactgtagca agtttaacct 617640
atattcgaaa ttccgttgat cccgcagttt taggaaccgc tattacatta cttaatgcga 617700
cactatcaat tggtaaagcc atttatggtt acatttttgg agtagtttat gaaatttggg 617760
gaagttttat aatgttcgga atttgtttga ttccttttgt cattgctttc ttaatgattt 617820
ctcgttctca ttgttttgat gaaatcgata aacataaagg tcatattgca taagtttatg 617880
gatagatagt tatatgctat ctatccattt ttagattaaa ttaaaatatt ttcttttaaa 617940
taatataatt tatattataa tgatattcat ggagaagttt atgaagaata tcacaaaaat 618000
gtttttattt atattatcgt tctacttagt cttaggttcc ctttggattg gaaaagatgt 618060
tatcattcat tatcaaaata ttgatggttt accaatccta ggttatcatg gtgtcctcga 618120
agataaagat aaagaaaaat actttgctaa ttatccatac tgtatgtcat tgagtgaatt 618180
tgaagctcag atgaagtatt taaatcaaaa taattatcat accttaacaa tggatgaaat 618240
caacgattat tatcaaaatc atacaccact acccaaaaaa agtgttgctc ttacctttga 618300
tgatggctta ttaaacttta aaacagttgt taaacctatt ttagaaaaat ataattttaa 618360
agctacttgt tttgttattg gctataaaac tacagtaaaa aatagccaaa acccttataa 618420
gcatcaatac ttaagaaaaa gtgatttagt aaatgacgaa tatgttgaat actattcaca 618480
ttcttataat cttcatcata acactaaata tcctaatacc aaactaattg aaacattatc 618540
cacacaagaa ataatcaatg attttaaaca aaatgaaaat attgtttcta gtaaatactt 618600
tgcctttcca tatggtcgaa catgtgacaa tgctaatgaa gcattgataa aagctaatgt 618660
ttcattagct tttggttata accaaaatag aacgatgacc tatcatgatg ataagtactt 618720
gttaccacga tatctaatgt ttagtaaaat gccaatgttc tattttaaat ggatcgttga 618780
ataaaaaatg acaaggactg tttgttcttg tcatttttat aattattata agacttttcc 618840
attactagca ataacctttt gataccaata aaaactatct tttaaatatc tctttccact 618900
tccatttcca taatcatcgt agtcaacata aatgtaacca tatcgcttat tcatctctga 618960
agtacctgca cttatcatat caattggtga ccagctcaaa tatcctaagc atatgactcc 619020
atccaactca attgccttct ttaactcatt aatatgtttt tgaagatact taattcgata 619080
ttcatcatga atctgattgt ctacagtcaa aatatcatta gcaccaaaac cattttcact 619140
aatcaaaata ggtaaattat aacggtagta tatctcattc attgtaattc ttaaaccaat 619200
tggatcaata gcccaacccc aatctgattt ttccaaatat ggattttcaa caccaccttt 619260
taaattacct tcccctactt ttctagcagg gtcatgagat gctactaatg ataaataata 619320
actaaaagat atgtaatcaa ctgtattatt tttgattatg tctaattctt cttttgagaa 619380
atttaaatga atatctcttt tttctaaatt ttttaaatac cagttaggat aattcccatt 619440
agcctgaaca tctgcgtata aataatattc ttgatttgct ctcattgctt taagaatatc 619500
atgcggatca cagcttgctg gataagttgt aaatgaagcg atcatacaac ccattttagc 619560
agttttatca attcttttta gctctctagt tactaatgca cttgctaaaa actggttata 619620
cagtccctga tgcactcgtg tttcatataa ttgatcttga ctaaagggaa ctgctgaacc 619680
tttaaatggt atttctaatg ccgcattgat ctcgttaaat gacatccaat attttattcg 619740
tcctttaaaa tgtgtaaaaa ctgtataaca atatgtttga aaaaatttaa tgacttcttt 619800
attacaccag ccaccatatt cagtcgcaat aactagtggt gtttcaaagt gagataaagt 619860
tataattggt tcaattttat atttaagtaa ttcattaata atattgtcat aaaatttcag 619920
tcctgcttta ttgggttctt tctcgtcccc tcgtgggaaa attctcgacc agctaaatga 619980
cattctaaaa gctttaattc ccattttagc cagtaaagca atatcctctt gataatgatg 620040
ataaaaatca ttcccccttc ttttgggaaa attattactt ttattttctt taagtttttt 620100
aatttcttca atggttaatt cctttttagc taaatgacgt tccttctttt cataaaacat 620160
aaaaacatcg gctattgaca ttccacgccc atcaaggtca tatccacctt ccatttgatt 620220
ggcagcactt gcaccacccc acagaaaatc tttatctaat tcacacatac cgaacacctt 620280
tcctttctct attattgatt tatgatctct tactccaatc gcaaaatatc atcattattt 620340
actactgtat tcatatttaa cagctcgact ttattataat gattagtatt tgttacaata 620400
acaataatag ttggatcata tcccgcatgg ttgatttcat caatgttaaa atctagtaat 620460
aattgtcctt tcttgaccat atcaccttct tttacaaaag cataaaaacc ttttccctcc 620520
attttaactg tatcaattcc tacatgtaat aatatttctg ctcctaatat tgaccttaac 620580
ccaattgcat gattagtcgg aaatacagca acgatcttag catcacaggg agcatataat 620640
ttcccttcat caggaataat agcaacccca tttcctaatg ctaacgaact aaaagtactg 620700
tcatttacta tttctaacgg caatacttta ccagtcccta cagcacctaa tatctcggta 620760
tcaacctcaa gcagttgatc agtttccttg attacatcat catttttttc aacaaattca 620820
tctttccaaa ataataatac taatactaaa gttccaataa atgaaattaa taaaccggca 620880
atataccata caaacccatg ttcagcaaac aatggtaatg ataaaattcc acctgctggc 620940
aaccccgtcg tatagcatcc agccccacca acaactgcac ccccgaaacc actcattaga 621000
catgccatga aaaaagcttt tttagccttc aaagtagttc cataaatcag tggttctgta 621060
attcctaaaa ctgagggaat tacatttgct gctgcaaccg atttaaaatt tttatttttt 621120
gatttaaaag caatccctaa tgcagcacca gtttgtgcaa atgctgatgg catcgtcatt 621180
gctaacaatg catctctacc agttgttgca agattattta aattgacagg aataaatcca 621240
cgatgtaaac caaaaataac taatggctgc caacatgcac aaaatataaa tccaaaaata 621300
attggattga aactataaac tgctaataat ccatctgtaa aaacatttgt taaaaatgtc 621360
actactggtc caattgctaa taatgataat ggagccataa taattaaatc aatcaatgga 621420
gtaacaaaac ttctaattat tgaaggcagt ctatcacgaa tcagcctatc caataatgat 621480
gcagcatata ctgcaacaat aatcggtact acagaagatg catatttaat taaaatcaca 621540
tcaagtccta agaaagataa ctttgcacct tcactaaaag ctgtcaataa ggttggatat 621600
aacattgttc cagctaaagt gactcctata aattcatcta ttttaaagta ccgtgatgca 621660
ctaatcgcta aatagaacgg cataaaatac aagattgcat ctgcggcagc atataaaatc 621720
atatatgttc cactttcagt tgttaatatt cccatactag taaatatggt taacaatcct 621780
ctcaatacac ctgctcctgc cataacagga acaaatggtg taaatatgcc tgaaaataat 621840
gcaaatatct tatccaataa tttcttattt ttatttgact gttcctttac agtacttatt 621900
ttagctgttg ccaagattgc tttatataca tcagcaacat gggtaccaat aaccacttga 621960
cactgtccac ccgaaaataa cacttgaaga atttctgaac tattttctaa gtttacttta 622020
tttactttct cctcatcttt taattcaaat cttaacctag tagcacaatg ctgtactata 622080
tttatatttt tttcgccacc aacatttttt ataataaatc ttgctaattt ttcatatttc 622140
atttttttct cctcctaata aaataaccta gaataaaaca tgtattcaat catgttttta 622200
ttctaggttt agcttgccaa agcaataaca atcctaatat tttaatcttg caatatgcaa 622260
agttaaatac aatttttccg cctgacttaa atctttttta taaatttttt gaacatgttt 622320
ttctatattt tttacacatt caaatgcttc tggatatctt tcaataacga tgtcaaataa 622380
tatatcatct cttttagctt ctttttcacc aaacatcagc cgctttgcaa aaaactttaa 622440
atgtgtcaca aaacgatgat agtctagaga atcctcatca aatgatatct cacaatatta 622500
agtatttctt gaataatttt ggtaatttga gttacttctt ccatttcact attaagttca 622560
gcattgacaa aatgtagagc aataaaacca acttcatctt ctgataaatt aaccattaat 622620
ttttggttaa ttattttcaa agcttctgct gcgatcttat attcctcttg ataaaattgc 622680
ctaatctccc ataaaagcgg attttgaaca ttaattcctt gtaaatatct ctctatagca 622740
tagtttatat gatcagtaag agttatatat attccatcat ttaactcttt atccaatcct 622800
ttccgtgcaa aatcaataat ttcatcagta acattaagaa cattgactgg aatatcctta 622860
atcaattcaa ggaagcgatt gttttgttta tcatttttta aataaaattg tttttcaatc 622920
atttcatcta gaacaacttc tccccgtgat ttttgatatg caatacctct tcccataaga 622980
ataatttcat tatgattttc gtcaagtgag cttacaatat tattattaat aattttatga 623040
attatcataa gacacctcct tttttgcata gaaaaagcca aactcaaata atatatataa 623100
gaaatatata tccatcaaag tttagcctaa ttgaatagta acaatctttg taattttatg 623160
atagcacttc caaaattaat tgtcaattac caatcatata tatcaaaaat tagttgttaa 623220
ttccttgatg cggcacaaac gaactatctg taattgcctc aaagcgataa ccacgtgctt 623280
tataattttc aattattgcc ggtaaagcct gaacagttgt tgatttggca gctgtatcat 623340
gaaatagaat attaatatta ttagctttac ttgcagtagc attagcaatt aacttgctga 623400
ctgctacatt atttcctgaa gcatctgtag aatcgccatt ccaatcataa tattgataac 623460
cgcgattgat taattccctt gacaatacag tcataatacc tggacaatat ttacgtgata 623520
ccgtatttga agaacctcca ggaaagcgta catatttggg tacaaaccca attatatcct 623580
tcaccatatt accgactttt gttaaatcgt caaaataagc ttctggtgaa gcataaacag 623640
ttttatagtc atgactatat gtatgcaacg ctattgtatg tcctttatca tgagcagttt 623700
taattaaatg attataaggt ttattattcc cagtaacaaa gaatgtcgcc tttgctccat 623760
aaacatctaa aatatctaaa atcttttggg tattagctga tggaccatca tcaaaagtta 623820
aataaacgat tttatcactt gtttgattat tgcttccaat tgctttcttt tcaactactt 623880
taatttcacg ctgcttttct attttgtttc cagaacgatc tatccctata taaataagtg 623940
tataagtccc ctctttttga atattcacat tactagaatc aaccgttaat tttggttcgg 624000
gatcacggtt atcactaatg ctgacaccac tattataatc tgtttttgcc cctatcacga 624060
tcgtcaaagg ctctaaccct gtaatttggg gtggctcact atctttagta accttgactt 624120
ttcccttctt ttcagttaca ttatttcctt tatccttaac ctgaataatt acttcaacag 624180
ttccctcttt actaaaatca taatcttctt taaaagaaac ttcagttttt gttgcatcat 624240
taatatttgt tgccatactt gcaggatcaa ctttcattcc taaatcaata tcaagatcaa 624300
caacatcaaa ctgtggtttt ttagtatcaa ctatctcgat cgttgcttca tattttttat 624360
ctttatatat atagattact ggatatcttc ccaacttatt ataatctatt ttagaaatat 624420
cagcctttac atctttaata tttccattgc gtacgcttgc gatatttttc atcacatcat 624480
aactatcatt aatctcgact ttgataatat ccgctttaaa gactatcggt gagcgggtta 624540
aaaaatatgt tgctactcca ccaactatta tgactagtaa tactgataca attacaatct 624600
tatttcctat agttaaattt ttaatttttt tcattatatc tttcccttaa ctaatttata 624660
tacttttagt atatgtcaaa cctcagtatt ttacaatctt tgtcaataaa actatttata 624720
aaaatcaact aaataaaaaa tacttatcta taatcagata agtatttaat cattattaat 624780
caattatagc acggacatta ataattccat ttgccgactc aatccgctca ataatatcag 624840
gtcgaacttc atcatttgta tcaattagtg tatatgcata ttcaccacga gagcgattaa 624900
ccatattttc aatattcaaa ttatgatcag caaataattt agaaatattt gctaaaatat 624960
taggaacatt tttattaata atacataatc ttgttttaga cattcttgct tgattgactc 625020
ctgggaagtt tactgaatta atgatatttc cgttttctaa atattcacaa acttcttcaa 625080
ccgccatctt tgcacaatta tcttctgatt ctggtgtact tgcacccaaa tgtggaagaa 625140
taataatatt ttcttgtcca attaattctg gtgcagcgaa atcactaata tatttattaa 625200
ttttaccgct tgcaacatta gctaataaat cttcattatt aactaaatca ccacgagcaa 625260
aatttaaaat tctgacaccg gttttcatct gtgcaaatgc ttctttgttc atgaaacctt 625320
ttgtttcttt agtactaggt acatggattg taatatagtc acattcttga taaatttctt 625380
ctaaagaagc tgcatgacga gcatgcttag ataaagccca ggccgcattt acgccaatat 625440
acggatcata accttttact ttcattccta atttaatagc tgcattggca acatttactc 625500
caatagcacc taagccaatt acccctaaag tttttccttc aatttctggt ccaacaaaat 625560
tacttttacc tttttctgct gttttagcaa tatcctgatc gtcttttaga ccatcaatcc 625620
aacgaatact ttcaacaatt tttcttgaag agagaaataa tccacataat acaagttctt 625680
taacagcgtt agcatttgct cccggtgtat taaatacaac aattcctttt tcactacaat 625740
catcaagtgg aatattattt actcctgctc ctgctcttgc aatagctttt agattttccc 625800
caaaatcata ttcatgtaaa gaagctgatc taaccaaaat agcatcttca ttagtcattt 625860
cttcgctata agcataattt tcgtcaaatc catctaatcc tactttagat attttattta 625920
ataattttat gttatacata attattctcc tatttgttcg ctgcttcaaa atctctcatg 625980
aaagcaacta atttttcaac accttctaat gacatagcat tatagataga tgctctaatt 626040
cccccaactg aacggtgacc ttttaaatta gtcatacccg cggcaatact ttccttaaca 626100
aacttagcat caagatcttt gtttggtgta gtaaaagtaa cattcattaa agaacgatta 626160
tctttatcac tatgtgcgat atagaaatca ctactatcaa gataatcata aagaagatta 626220
gcttttttaa tatttctttc ttgcataact tcaagtccac ccatactatc gatccattcc 626280
aaaactagtc ctaatacata aatcgcataa gccggcggag tattatacat tgaatcattt 626340
tcaatcatca atttataatc taataatact ggtgttgtcg cagcaacttt ttgtaataaa 626400
tcttctttaa taattgctac tcctaatcca gcgatcccca tatttttttg tgcacctgca 626460
taaatcattc caaactttga aacatccact ggttttgata aaatatttga tgacatatcc 626520
gcaattacag gaacaccatt agtttctgga atatatttcc attcagttcc gtaaattgta 626580
ttatttgcac ataaatgaac ataagatgct tcaggatcta atttcaattc gtcttgagtt 626640
ggaatatgtt taaaattgtt ttcacttccg tcataagcaa tattaatttc cccaaatttt 626700
tttgcttcgg ctgcagcttt tttactaaaa gctccagtta caacataatc agctttacca 626760
ttttttaata agtttaatgg aaccattgaa aattgttgtg ttgctccccc ttggataaac 626820
acaattttgt aatcatcagg gatattcatt actttcttta ataacccttt tgttttttca 626880
aaaatgtcta agtaggaaga ggatctatga ctcatctcca taacactcat cccactattt 626940
tcatagttca acatttgttt agcagctttt tctaaaactg gctcaggcaa cattgaagga 627000
cctgcagaaa aattcagtac tctcttttca gtcatatata tacctttcct ttcttgtatg 627060
tgaagtctat tatattgtat acaatctaat ttgtaaaggg attttgtaaa aaattgtata 627120
caattataca tcgtttcata aaaaagctat ttttcttagt aattatcagt ttcattatat 627180
gctggaacat ttgataaatt cacgatattt taactacatt tacgataaaa taaattgaat 627240
taaatacatt tctaagatat gatgaaaagg tacatatagg agagaaaaaa tgaaaagaaa 627300
aaaactaaaa ttgaaaaaac aagcttactt tgttattggt ggcctcgtca tcctagctgc 627360
ccttatacta taccttattt tatgtttagt aacaggggga gacaattttg tttcaaatac 627420
aactatcaat ggtattaaag ttggtaatat gaataaagaa gaagcacgta aggctataga 627480
acaacaatat caaaatgatt taaatccccc tactttaact ttattactcg atcaacaaga 627540
atacccagtt gatttaactg ataatcttac attcgatagt aaaaaagctg tagataaaat 627600
ttctaaacag tctaatagtt cattcttcag acgaggatat aactatttgt ttaatcatga 627660
ttatacagtt ggggtaaaaa taaaaaataa agatctttta aatgaaaaaa ttactaatag 627720
tcaaattcta aattatagta ctttgactcc tactaactat gaacttaaag atgataaaat 627780
tattttcact aaaggaaaat ccggtaaaac agcagaatta gaatcagttt tcaatacaat 627840
taataaggca ttaaataatt atgattttaa agggaaaatt aaatattctc cagtagaaca 627900
taaacttaat gatgaagaaa taaaactaat tcatgaaaat ttatcaaagg aagctaaaaa 627960
tgctactcta gataaaaata acaattatga aatcatcgat agccaagtag gtgctaaatt 628020
tgatttagaa gatgctgttg ctaaatacaa taaaactact gaaggtaaac agtttaccct 628080
aaatgctacg atcattaaac ctgaaataac caaagaaatg ttagaacaaa atttatttaa 628140
agatgtttta ggtgaatatg cgactaacgt cagcggtact tcagttcgta aaaataatgt 628200
taaactttct ggtgataaat gcaatggagt tattttattg ccaggtgagg aattctctta 628260
taataatgtt gttggcaaaa gaacgaaaga aaatggtttc ggtgaagctg cagcctattt 628320
aaatggagag actgtgcaag aagttggagg tggaatctgt cagacatcat caactttgta 628380
taatgctgta ttgtacgcta atctaaagat tactgagcgg actaatcata cttttgtttc 628440
tggctatgtt ccaatcggtc gtgatgctac agtatcttgg ggtggccctg attttaaatt 628500
taaaaatgac caggcttatc ctattaagat catcgcttct tatgaaaata gtcgtctaac 628560
aactaaaatt ttaggtacta atgttaataa tattcgtgtt gagctaaaaa gtcaaaaact 628620
tgcttcaact aattataata ctaaatatga agacgatcct acattacccg aaggacagac 628680
aaaagtaaaa caaaaaggaa ctccaggtag taaagcaaaa tcatggcgtt atgtttatga 628740
tgctaatggc aatttaattt catcaaatga agaagcatat agtgtatata aaggacatga 628800
ggaaattatt ttaagaggta ctatgaaaat aactgaacca gctacgcctg caccaactga 628860
acctacaact ccagcacaac cagaaacgcc taccattccc aataatgaaa catcgtagaa 628920
tcttaaatta aatactggtg gaatttttcc acctttttct ataattaaaa agattattac 628980
ataaaataat aatcttttta attattttat ttttgtgcaa tcttccactt ttttaaacaa 629040
tactgatata tctcttgttc tgaaatcatt aacgaagcac tagctagatt tatttccata 629100
ttcttaccat tcttttcaag aattatcaga aaataaaaag gctcatggtg cagctgaatt 629160
tccgcaacct tctgccataa aatcactttt ttccatagcc tataagaagt gataccatct 629220
ttatcaatta caaacttttt cattccaaaa aatatcaatt ctaataattc aatagttcca 629280
actattacaa ttaccaaaga aaagaactct agcaccccaa atataaataa acaaaatatc 629340
attatagctg atgatacatt cgaaataaat cctgaagcta ctattggaat gcttatcata 629400
attaatgaaa atggaattat ggataaaata agaatagttg ttaaaatcat atcttttcta 629460
ataataattc tttccacttc ttttatcctt tccaccattc aagtcattac attaaaacat 629520
actttatttt ctgtaaactt gaaaataatt aaatattgtt tacgaataca aatatcaggg 629580
tttgtattca agtgttttgt aatataaagt atttcttttt aggaagcaaa gtagactttt 629640
tctcacatag aatatataat taaataaaca aacttaaata agatattttc ttaattttca 629700
caaatattat gattgaaaaa aacaggaaaa aaggtctaca ttttttcctg tttttactta 629760
aataacttta tttatattga ttcataatcc tttacccatc tagtaaaggt atgattattt 629820
gtacttaaac gacgcgaagc ttcagctttg ctgattacat tttttcgcca taaataataa 629880
atttcttcaa aatcgtcggg aatcgttaat tttggtcttc caaatcgtac gcctctacgt 629940
ttagcttcac gaattccctc ggcttgtctt tgacgtgtat tttcgcgttc tatttgagca 630000
acataagaaa gcacttgcaa tactaagtct gcaataaatt tacccgtaat tccatcatgc 630060
ttttcacgtg tatctaataa aggaaaatca attaccacaa tatctactcc gattttcttg 630120
acaatataac gccactgttc aatgatttca tcataatcac gtccaagacg atcaattgat 630180
ttaatgtata aaatatctcc ctgttttaaa acctgaagaa gtttttgata atgaggacga 630240
ttaaaatctt taccggactg ataatcaata taaagctggc tccctgtaag tccaacctct 630300
tttaaagctg taatctgcct atcaacattt tggtctttac ttgatacccg tatatatcca 630360
tatttgttat attccattct atattttcct cctcgagtaa aaattatggc atagggaaag 630420
ttagaatgct ataaatggct aattatttag ggattctttg catcttacat cgtcagcagt 630480
gataaatcca tttttataat cgtaatacga taaaattaaa acagaaacaa taatcaacaa 630540
actatcgctt ctgtttaact aataaaattt aatttataat tataacatcg tcttttcata 630600
aatatcagca atgttagttc caacatgatc tggttgatga gcatcacttg ctgtaatcat 630660
cgatactcca tgttctttta atatctttaa caattcttcg cttaatccca tatctttatg 630720
attataacga taataacatc ctgtattatt ttcagctttt acattatgtt caaccaacaa 630780
atcagctaac tgatgataag ttggtgttaa atcataggtt ggataataat taaacatttt 630840
tattgtatct ggatgtgcta attgcgtaaa taaatcagac ttaaccaatg aaaaaatcaa 630900
ttcataataa tcacgataaa tatcatcaac atcaaattta ttccataaaa tatctttaga 630960
gaaattcatg tcatataatc tgccattaat tgagtgtatt gccccaacaa caaaatcata 631020
attatggtta gctaatactt ctccaatctt cttttcatgt ttaggcacgt agcatacttc 631080
taaaccaaat gtaacttcaa tcggcaaatc taatgcttta acttcctcaa ttaatttatc 631140
ataatcatct aaagtatcct taaatttcat tgctttattc tctagccatt ttttttgcaa 631200
tggctcttct tttaattctg tataaatctc ttcaaactct ttaaaacgat gtgtgtgatc 631260
taaaatttga atctttgtca aacctttttt aacagctgca tcaacaaact ttaatacata 631320
ttctttattt agatccccat attctaaatg catatgtccg tcaatcatct ttatcacccc 631380
ttcttttttt atgattatat gcaattctta aaaaaaagta cagtaataaa ataaaaaaag 631440
gagccagggg agactcctta taggatggat gagtttttgg gagagggaat catccatcat 631500
ttaagttgta aaatatatat gaggggatta atatatttta catattatta tggtttgtct 631560
ttcgacacta ttatcctagc accgctctat gaattaaatg tgaaccgtat aattttttaa 631620
aataaaaaag gagccagggg agactcctta taggatggat gagtttttgg gagagggaat 631680
catccatcat tcaggttgta aaacatatat gaggggatta atatatttta catattatta 631740
tggtttgtct ttcgacacta ttatcctagc atcactctat gaattaaatg tgaactaatc 631800
taaaacaaat aattagaaat tttatccttc gattatttga tccaaccatg caccctacaa 631860
gcattataaa ttccatcact agtattgcga tcagttatat aatccgcttt agcttttaat 631920
tcatcacagg cattacccat cgcaattcga tagaaacgtt catcaaacat aacaagatca 631980
ttataatcat ctccaaatac tacaacatca tcaatatttc cttttatcat cgcaatcata 632040
tcaactattc cctgcttttt atcatctggc tgaaacatta aatattcttg ttcaaaacgt 632100
aatgaaccta acgtatcttt taatgttaat cgtgtttctt cactagctgg aatagaaata 632160
taaattttat aaatattttc taaattatga taatttattt cactatcaat tgtataacgt 632220
gttggttctt ttcgataacc tgcttgtttt aaaaataacg tatttttact gtatacatca 632280
atactatcaa atggagctat taggattcca tagcctaaat tttctgcttc atcaataaca 632340
gccaatgctt tttgccgatc caatggtgca ttttttacta actgatgatt tatgacaaga 632400
ccattaccac cattacaaac catattattt aaaccaactt ctttaagaaa gtttttagct 632460
ttataataag cgcgtcccgt tgcaatagct acaaaattac cattttcttg taatttatct 632520
agggcttctt gggcacttgg aacaattttt ccagttgtat tatccgtcaa agttccatcg 632580
atatcaaaaa atatatattt catatcattc ttctccaatt tctttaaaga atccataaat 632640
aacagctcca caaagacttc ctgctaataa agcaacaata tatctaaagg gatgcgctat 632700
taatggtaat acaaagattc caccatgagg aattctaatt ccacaattat aaagcattga 632760
aaaaccacca gctactgctg aagcaacaat gcaagctaat gttactaagc gggggtcttt 632820
ttgaacaaaa ggaattgtcc cttcagaaat aaacattaag ccttttaagt aattttgaca 632880
acctagttta cgttcagtta atgtaaattt atttctaaag aaagttgtac taattgcaat 632940
tgctaatggc ggtaccattc cgccggccat tacagcagcc ataacatcaa agttaccttc 633000
aacaatttga gctattccaa aaagataagc aattttatta actgggccac ccatgtcaac 633060
agacatcatt cccccaacaa taactcctaa aattagttta taaacaatat ccatactacc 633120
aataaataca ctaatagtct gatttagact tccaacataa ggactaatca aatatgataa 633180
aacacccgta atcatgaccc caaaaatcgg atatattact gttggcttta taccatctaa 633240
acattctggc aatttacgac aaattttttg taataaaatt acaacatatc caccaataaa 633300
gcccgctatg attgcaccta aaataccagg actaggcata ttttgtagat acatattatt 633360
taataacatt gcagccccgc cagcaagagc tactgcaaat ccctgctgac ttgcaattgc 633420
ctgaccaata aagccagcaa ataaagcaac gatcatccca ttaacggtta tccccagaat 633480
ataactgtta cttagccaaa tactatcata aatttgtttg attccaaata aattataact 633540
tgctgctaat gaagcaattg aaatcaatgc acccgatcca ataatgattg gcaatatttt 633600
acttaaagca tctgtcaatt gggtatataa ttttcgccaa attccctcat tggcagaact 633660
actaaccact ttatctcctt gatgatgata aatttctaca ttaccattta ttgcttgcga 633720
caataactcc tctgctttat taattccatc agctacttta gttataatta caggccgacc 633780
atcaaaacgt gacatctcca cttgtttatc tgctgccaca ataatacatc gtgccttact 633840
gatttcttca gccgtaagaa catttttagg ccctgttgcc ccatttgtct ctactttaaa 633900
taatatgttc atttctttag cttttgcttc taaactttct gctgccataa aagtatgagc 633960
aattccagta ggacatgcgg taactgctaa aacttcataa ttagtaccgt cagtttcttc 634020
ttttactttc actatttcat tttctttatc atcaattaat cttaaaaatt ccactgcatc 634080
actagcatta attaagtttt ctttaaaatc attatccatt aacatcccgg ataatcttgc 634140
taatgtttcc aaatgaatgt taccaccatc aactggtgct gcaatcataa aaaacaaccg 634200
tgctggttga ctatctaatg attgataatc cacaccatct ttaactatca ttactgctag 634260
tccaggtttt tttactgctg ctacttgggc atgcgggatt gcaattcctt ctccaattcc 634320
cgttgtactt tgagcttcgc gagctaaaat acctttttta aaggctagtt tatcactaat 634380
atttccagta cccaccatta aatcaactaa gtgatcgatc gcttcttctt tattagcaac 634440
ttccccattc atatcaattc cctgcagaca taataaatct gtaattttca ttattcatcc 634500
tcacttattg tttttaataa ttcatctatt ttttcttttg atgccaaatc ttcactgaat 634560
gcagttgcac taccagtagc tgtagcctgt tttaaagccg ttttgaaatc atttgtctta 634620
atataaccgt aaataaatcc agcgaccata ctatcacccg ctccaactga atttttaacc 634680
tcacctttag gagcagatgt tatatgtaca tcattatttt gatcgactaa tactgctcca 634740
tctccagcca tcgaaactaa cacattttta gctcccattg tttgtaattt cttagcataa 634800
acaacgacat cttctttatt tttaatttca acattaaaaa tttcagctaa ttcatgatta 634860
tttggcttaa tcaaaaatgg atgatgcttt agacagttca tcaataaatt attagttgca 634920
tcgactacga tcaaaacatt ttttgatttt acatattcca taattttttc atatatatca 634980
tccggcatac tgcctggaat acttccagat aaaactagaa tatcaccatc ttttaaatta 635040
tctaacttac ctaataatgc ttgaacttgt gcatctttaa tttgtggtcc catcccatta 635100
atttcagttt cattatcaga tttcatcttc acgttgattc ttgataatcc ggcaacttca 635160
acaaaatcag tttttaatcc tttagcttct aatccctctt tgattgcttt gccagtaaat 635220
cctgcgataa atcctaacgc cgtacttttt tcacctaaag tttttaaaac gttagaaaca 635280
ttaattcctt taccaccaaa aaacatgttt tcttgttttg ttctattgac aattccggtt 635340
tcaaaattat ctactttaat tacataatca attgctgggt ttaacgttac tgtatatatc 635400
atcttaattt tctccttaag ttaattttta atccactctt agtatatact taggtgtatt 635460
ctccgtcaaa ttaatgagtc aatatttatt ttcaaataaa gaaatttaat cttataattt 635520
taattattta aacttaataa taattttaac tccattaaca agcttcttac aaaaacaatt 635580
gaaatcacct tatatttatg atatctttta tatagttagt catagctaac catataaaag 635640
gagtgattat atgccatcaa ctgcattatt atttgaatct aaacttgtta ctttttgtag 635700
tcctacttta ttaaaaatga aagctggaaa tatttttaat attagcaatg agttcaatga 635760
attagaagag tgtttaaatt attacaacca actatgcaat caaagaggaa tatacatttc 635820
gattattcat gaaaataata attcaaaaat gatttatgtt tatcaaaaag aaaaattaaa 635880
taaccttttt aataaccata aatttagagc tgttctaaat aattatcatt acccttatca 635940
agatatcgac agtctaataa attggctaaa gattagaatg aatagtagtg aatttcctca 636000
tgaaatcggt ttgtttttgg ggtacccttt gactgatgtt aaagggttta tcaacggtgc 636060
tgattataaa tatattggat attggaaagt atatagccat gttccccaaa ccctctgtac 636120
ttttgaccga tataaaaaat gcacacaaga attaaaaaga cgtttttgtc aaggagaacg 636180
aattgaacaa ttattagccc atgtttaaaa tcataaccat ttcaatagca cgtgcctttt 636240
tgtctcataa taaaaaagcc tgatcataat gatcaccggc tttctattat ccaattgaag 636300
caactattgt agtaactaaa ttatcaatat catccacttg ctcagttttc aaagttgact 636360
taattgtgat tggttcgttg atgatttcca tatccttcat cgtctctaat ttagtacgca 636420
tgtgttttgc gcataatgct ccccatgttc cattttctaa taacgctaca cttcttttct 636480
ttaatgataa agcaatcata tcactaagga agttttccat tggtggaaaa attccactat 636540
tatatgttgg cgctgctaaa atcaaatgac tataatggaa cacttcacta attaaattag 636600
aaacatgcac tttagatacg tcatacattc taacattttt taccccggct tgcttcaatt 636660
ttgaagcaat tatttccatt acattttcag tattaccata gatcgaacca taagctaaaa 636720
caacaccttt ttcttctggt tcatatttag accaacaatc atatttgcta actatgtaat 636780
caatattatt acgccataca ggtccatgaa gcggacaaat tgtggcaatt tctaaactac 636840
tagctttttt taataacatt tgaacttgtg gtccatattt tccaacgata ttagcataat 636900
atctcctagc atcatcaagc cattcatgtt caaaatcaac ttcatcatta aataaagctc 636960
cgtctaatgc tccaaatgtt ccaaaagcat cagcactata taatgtttta tcataactat 637020
cgtatgtcac cattacttct ggccaatgta cgagtggtgc catcacaaaa gtaaaagtgt 637080
gttttcctgt agttaaagta tcattctctt taactactaa cttattgatc tcaatcccaa 637140
aaaattgatc aatcattgta aatgttttag catttcctac aatcacgact tcaggataac 637200
gatttatcac ttcttttaaa catgcacaat gatcaggctc catatgatta ataacaatat 637260
aatccaatga tcttccttgc aatgctgttt caagattatc aaaaaataag tgtccaatcg 637320
accaatcaac cgtatctaat aaaatggtct tttcatctaa cacaacataa gcattatatg 637380
aaattcccct tggaattgga aaaatatttt caaataaact taagcgacga tcattcccgc 637440
caatccaata aacattctca tttacttctc taatacaatt catcatcaca gcctcctaaa 637500
tcacttttag tataaaccta atattctaat tttactaata tgatgcttat attatttcca 637560
aaccctaaac tattatccct caaagattag tttagcagct ccatattagc taatatctca 637620
tttatttttt cttcaatttc ttcttcactt ttaccatcta actgctccaa caattcttga 637680
ataaaaggat cattaaatgc ctcatcagca gtttcaaggc caaaagcatc cattatcgcc 637740
ccttcaattt ctagcgttat ctcatcttca aaataatcaa tatcatattg actaataaaa 637800
ttcaagacta agaaaagaac atttaaatta tttactacga ttcgttgtgg tttaccataa 637860
cgattagcat attcaagcaa tccatcaatt aaagcttcac caataatttg taaactagga 637920
aaatcaactt ctttaattaa ataatcgctt tctccggcaa ttacggcata aacatttaac 637980
tcattggttt tatctgtatt agtcattggt aaacagacaa catcaacaca taaacgttct 638040
gtattttcac gcttagtttc aagctcatgt tcacctaaat agccaaaatc atagcgattt 638100
aagtcaattt gtggttcatg aacaaaaata gcactctcct taaatttacc atcttcaaca 638160
tatatttcaa taatttcatc agactcacta cgattttgat cttctttaat cccatttgca 638220
aattctttta ataattctaa aattaccctt gcttcctcaa cttctaataa gcatggaata 638280
tatcccgctt cattacgaaa agcagccaaa tagttatcct catctaatgc cacatcaaaa 638340
tcaagttcct gttcagataa taaaatagtc cagcagttgc aaaatgcatt atttattcct 638400
tcattagcaa gattataaaa accctctaaa agatcattat aagtttcaaa taattcaatc 638460
acataacctt ctaatgtttt taaaataacc caatatgtag tttggttaga tactagttta 638520
atcacttgat tatcagtaaa ctcacgtttc ttcactaatt cttttaactg ctctaaaatt 638580
tcaataaact cattttttaa cgggctatta tttaatattt catcaacccc taacaatgat 638640
aaacaactat taatatcttc tagatcaaaa ttaatatcca gatcatctcg acttaatata 638700
atttcttgat aacgttcaat tcccccacaa tcctctatca aattattacc acaaaattca 638760
actacaacag gatagtgctc aacgccctct aactcttgtt caaccgtaat taaaagttgc 638820
caatcatcac caaagtcata atggtagtaa attaccattt ctttttttaa ataatccgca 638880
atccgttcaa gattatcaac tatctcaacg tcatcattta tctgattttc aatatctgtt 638940
tcaccaccag gaatccagat ccctaattcc ttgatcctaa attcatatag atgataatct 639000
tcaaaaccaa ataaagtttg gattaactga tgcagatctt caaaactaat tattgcaggt 639060
attttaatac gccgccatat aggatccgca cacccctcca catctatcct caattgatat 639120
ccattcatct tttatctcct cagttctata taaactatta taacaaatta tattattgaa 639180
gtaacgcctt tatattgaga agataaaagg gatttataaa taattatcac gctcgactat 639240
tttcaacaat caatgttaaa tgttttgtga aataacgatt ataaatcaca ataatttggc 639300
caataaatcc agcagataat attgttccta tcccaattcc aataattttc cccgccaaac 639360
agtatgtagt aataattgtg acaagcatca ttccacaatc aaataataat tttgtcttac 639420
caaactcttt gtcaatcacc tggcttaatg ctttgaccat accatcagca ggattaggaa 639480
ttaaatctaa cattacaaca acatatgctc ctaaagcagt agctaaaata gcaatcgcta 639540
atagaactaa tgcaacaggt aatgaagtaa ctgtaaaatt taataagtta ttataaaaat 639600
ctaaaacata tcccataaaa taagaaaatg gaatttgtaa taaaacttta aaatctaatt 639660
tctgataaat caataattgc actccaacaa aaataatata taaaatagtt gttgccatcc 639720
ctaatgataa attagtcatt tcactaattc caaatggaac tgaattaatt gctgcaaccc 639780
ctaaaccagt ttttgtattt aagacaattc caaatcctaa aatcaatatc cctaaaaaat 639840
ataatcctaa cctttttgcc ataaacaccc tccttatttt tctttatttt acaatattac 639900
ttgatattat cagttctttt tcaacaaaag aaaaaatatc cttccaaaag aagaatactt 639960
catcaatcaa tttttaaatt gacaattcca gtttttgaat atcgaaaaac taaatatagc 640020
cattttgctt caatcaactc ttgttttctg ttcaatagat cactaataat agtattatac 640080
ttttctaaaa ctgccgcagc ctctttccag atttttccct cgattaaatc gtagttatca 640140
attacttgag caacgatcat tgagtctatt tctcctgctt gtgccatttg atttaaaatt 640200
tcacaagtct tttctttact aaaagaagtt ttataactgc gctttccaca tagtgcactt 640260
acaatatcac ttattgctac aatccgctgc tcttgagtca actggttttc ccataaacta 640320
tgcggataac ctgaaccatt cagtttttca tgatgccgac acgcaatttc taaaatttct 640380
tgatctattt tttcttctaa taattctctt gttttaagaa catgactacg cattattatc 640440
atttgctctt gagtcagttg acccggatat tctaatattt caattggaat tccaatttta 640500
ccaagatcgt gcatcattgc accataatag atcttttttg tctgttcaga acttaagctt 640560
aataatcttg ctaactctaa agatatcgtg catgtggtaa tagtatgtgt aactgtaaaa 640620
taactacgaa aatcaattag agaaactaac atatttaaat aactatccaa ctattctaat 640680
gaaagcgaaa tatttaaact agttactttt tgccattttg aaaatggatt agttgtaaat 640740
tgatagactt gatcaacctg ccaataaaga gtagtaacca aattttctac aaatctagtt 640800
cctgactcct tatctaagta atctttaagc atgctataat catttgaagt ttgtaaaaat 640860
acatcaattc gatcacacaa attaataatc tgagagatat ttttaatttc gtcatcaata 640920
taaatcattt tttgataatc aagatgatga taaagaatag caggtgccaa tttatctagt 640980
ggtgaaaagt tctttatgaa caaataacca taaatagcat gttgccatat attttttgtc 641040
tcaaaaataa acatttgatc aattttttct gtcttatatg ctccaatatc atgtagcatt 641100
gctaacataa aaacatcttg caagtacttt tgttcatgac tattttgagc ctcaagcata 641160
cgatatgtca tattagctac tcgtaaacca tgatcaatca atcgcgaatc aacataattc 641220
aaacaattac ttataatttc aataaaacct tcattattta ctcctgcaat attattcaac 641280
ttatttttcc atcgcatcca ctgacacttt ttcctctcga taaaatatca atacaaaaac 641340
aattgccagt aaacctgcga ttatcttact aatcatatag attatgacgc cattaccatc 641400
gactacacta gaaatgaatc ctagctgtcc ccctaaaaca taagctccac ttacactaaa 641460
agcggcattc atcatcttcc ctttacgatc catttgtgaa aacaatggaa tcattgcaat 641520
gcttgtccca aggcttaata gtagtcctat cacactagca ctattgacac ccaacttttg 641580
accaatcatg aaaatcattc gtgaaaaacg tttaataatc aaatcgctta aaatcattga 641640
tccgcacaca acaatgcaca tccgtaaaac aattaccatt gcatcactaa ttaaagcagt 641700
tgtagtaaaa ggcaatgtat caaaaaacag ctgtaaaaca accattccaa acaacaagat 641760
actaataatt ctaatcaaat aaccaaataa tgttaaaaca aaaatggttt tatcataaga 641820
aacatataga gcaattacca agataacaca aagtataatt attggtaata agttaattaa 641880
taaattagga atttgtaaat accaggcaac tgccactaga attattggta aacttaaaat 641940
cccataaact aatccactaa taaatggatt taaatcttcc ttttttaaag atgctaaaaa 642000
aattggtaat tgaaaactaa ttgtttgtcc taatgttgca gtcaaaataa cccctgaaaa 642060
aatcaaaaaa gtactattac caagtcccga aacaattgaa aacccaccca tatcaggtgc 642120
aagaatactc ccaataacaa ttgatggatc taatgatgaa tcggcactta ttttagtaat 642180
cacatctaca ttattttgaa tcaatgtaat tgcgatacaa taaaacccaa tcatactcat 642240
ggcaattcca cccatcgaat ccatcccttt atcaaaagca gctactagtc ccaacttatt 642300
attcaagatc ttgtcaatca agccaatcaa gcacaaaata agcattatta atataaaaaa 642360
attcattatc gtacctcaat ttccatattc ttccaatatt ttaccaaaca aacctcaaac 642420
aaaaaagcct attcggcttt tatttaaaat attcagtaat attatcctta tcatcaaaat 642480
aattgatctt cattgcatct ttagcacgtt taagtgttgc attcgctttt tcattagctt 642540
taacacaacc atcttctaac actttcataa cagcagcaat atcagcttgt aaaacagctc 642600
ttctttctct aattggattt aatgtttctt ctaaaacatt aaataaaaat ttttttattt 642660
taacatcacc taaaccacca cgacgataat gctcttttaa ttcatcaaga tttttataat 642720
caggtaaata tttttcaaaa tattcatctt tgcaaaaaca atccaaataa gtaaacactg 642780
tatttccctc aacggttccc ggatcttcaa cttttaaatg atttggatct gtatacatac 642840
tcattacctt tttccgaaca tcttcactag tatccgcaag ataaatacaa tttccaattg 642900
actttgacat ttttgctttg ccatctgttc ccggcaatct ttgacaaact tcattttcag 642960
ccaacataat ttttggatct accaaaacat caccataaat ccgattaaaa ctgtgaacaa 643020
tttctttagt ctgctcaatt aacggcattt gatcttcacc aacaggaaca caagtggcat 643080
caaaagctgt gatatcggca gcttgagaaa ccggataatt taaaaaacca actggaatac 643140
ttgtttcgaa tccacgctgt tttatttcct ccttgatcgt tggattacgt tgtaatcttg 643200
aaactgtaac taaattcata taataagccg taaactcaaa taatgctggt acttgagatt 643260
gaataaacat tgtggttttt tcaggatcta aaccaactga taaataatct aaagcaacct 643320
ctaaaatatt tcgtcggact ttttcagggt tatcagcatt atctgttaaa gcctgagaat 643380
cagcaatcat aataaaaatt tcatcaaatt ctcctgagtt ttgtaattcc actcgtcgtc 643440
ttagggaacc aacataatgt cctaaatgta atcttcctgt tggacgatcg cctgttaaaa 643500
taatattttt catataaatc tccttctttg attaaataaa aaaggctttt atcctcaagg 643560
ataaaaacca ttatgccacc ttgtaagaca ccatcatgtc tgtttttctt aacgcgaaaa 643620
gcacggcgcc actactccag ttaagtttca ttttgcttct aaccaggccc attcatcagt 643680
atctttatct tggctctcac cagccaccaa gtctcttaaa taaagattag ctgtttactc 643740
ttcctagatt atcgaattta ctatacttaa aatcataaaa cggatataaa atgatgtcaa 643800
tagtttatta ataatcttca attattttta tttttttcta caatctatct tgattccaat 643860
gcctcttctg tatattcaac aaaatactct tgataataaa taattctaat taaatctaag 643920
attgccataa tttgataatt aaaactaatt ccatcaaact tacccggtaa actaaagaaa 643980
tacttaatac aacttaagtt ctcattctca agtagttgat tttgggtaat caataatgtc 644040
ttactcttgc ttaagtgccc taaagatttt ttcgctaaga aatctcttaa tgaacgccca 644100
gtagatgaaa agaatactac aaaatcattt tcatcaaatt taatatttgg atcataagca 644160
tgatattgaa ccacattttt acctaatgta attaaatcag tttgaaattc aacagcaata 644220
ctagttggaa acagtcctcc aacaataatt actcgatcag catcatatat atcatggcat 644280
atagaaacaa tattatccat aaaaatatca taatcattta cttcaatcaa tctgaataaa 644340
tcacgataac tcatacttaa taatcttgct cgaatttggt cattacgtaa aatatcatca 644400
gctaccagct tacgatgaaa gtcctcatag ttatcaaaac caagataatt taaaaatcct 644460
aggatcgttc gtggatcaag atcactttct ttacaaactt gtgcaaatgt atattcaatc 644520
attcgatgat aatttgcaat tacaaaagta caaaattgat agtaaccgtc ataaaataaa 644580
gtgccattta aatacttaat aattcttgat aacaatacat cacccataac acaattctcc 644640
cttcaagcaa atatttactt ttctacactt atactataac aatctttgtt gtcaggcgat 644700
attaaaaaag aaacattgaa aatatttttt caatgtttct ttttaattta aaacaatcct 644760
gttataatcg ttacattcat tcgtcatggt ttgtcatttt caaatatgtt tctgttttat 644820
atttaacatt tttatcatag tctaatttaa aataacatgt ataaatgcaa tctaacaaat 644880
aaagtaatga taaccttgtt gaaaatgaag aaatcttatt ataatgattt tcatatggac 644940
ttaagtaaag attataatca caaagactaa ctaatgactt tagcgtcgtt gaagaaatta 645000
atatgattgg agtattgttc tttttcaaca atttaacaat tttgtcaaca atcattcccc 645060
gtccttcaaa gctaacaaca attgcaatat gttccttgtc acttgaggca gctgctaaaa 645120
gctgttgata ttcttcaacc ggaacattaa caaaacgacc gatttctgac atttgaaact 645180
taaagttttc aacaaagtaa agattaccag ctgaagtgta catatcgatg aactgagcat 645240
tttttagagc tgaagcaatc agtcgtaatt gatccaagtc aattagatta ttcgaggcaa 645300
tcaaagtctg ctcgtataat tctttcattt tcattgtaat ctgatactgc gtctcatttt 645360
gtgaaaatgg atagttataa tcaattgttt tcttttcttt caaataatct cttattgatg 645420
ttgataccat tactttaagc tgtgctaaac cattaagctc tagtttttta cacagacgat 645480
aaatcgttgg tattgaaata aagcaagcag cactaatttc atcagcactc atattaataa 645540
agcgttctgg attatttttc atataatcaa ctaaagtctg ttcattggta gttaaatctg 645600
ttaaattatc caatcgacta aatatattca ttttctcagc ccccttatcc tcgtatcatt 645660
ataataacac tttgacacat aaatttccta aataaacaaa taataaacat aagctaacac 645720
tcagtaaaat atatcctccc gccatcaaaa acttaccatc actaagcaga ttcatacttt 645780
ctagtgaaaa agttgaaaat gttgtaaagc cgccacatac cccagttttc aaaaataaaa 645840
tccagcgtga ttcaagatta tacttacttg ctaacgctac aactaatcca attacaaatg 645900
ccccaatgat attgatcatc atagtcataa aaggaaaagt agtatcttta attataatta 645960
atcccattaa atatcttgat acagcaccaa taaagccacc aattccaact gctaaacatt 646020
ccaacataat tatctcctct atataatctt attttatgat tattcaaaaa tttaagcaag 646080
taaaaaaggg aagtttactt ccctgccaaa taagcttttg cttcatagct tcttaatatt 646140
tgttttaaat catcttcata attactaatc agcaaagttc cttgaataaa ttctaaatct 646200
atttccactt catctttact ataattacaa ataactataa cctgttgttc gtttaatgtt 646260
cttcgataag cataaacttg gagatgttct tttaaaagct gctgatagtc accatagatc 646320
aatacctcat attcttttct taatcgcagt agatcacgat aaaaataata taccgagtta 646380
gggtctttta aagcgttttc aactgtaata tttgtatatt tttgacttgg agcgagccac 646440
ggctgaacaa tactaaaacc tccaaaccta ctgttatccc acggtattgg catccgagca 646500
ttatcacggg aacgtttacc aaaataagca atgatcgttt cttcatcata attctgttta 646560
aaaacttcat acttatttaa tgcatcaaca tcgcgatact gtgtcattga ttgataatat 646620
gcatttgtca ttccaatttc ttcaccttga taaatatatg gtgttccttg catccaaaac 646680
atgaataatg ctagcatttt cgcagatttt tcaagataaa aaggggttga atcatcacca 646740
tatttagaaa ctgcacgtgg gcggtcatga ttatcccaat ataaagcatt ccatgcttta 646800
ccattcaaac ctgtttgcca ccgttcaaaa actactttta aatctgctaa tttaggacgc 646860
tgataagtta aatttggtcc tttatctaac gacatatgtt caaactgaaa aatcatcttc 646920
aattcacgac gatcaaaccc tacatataat agagcatctt ctacactaac atcagctgtt 646980
tctcccactg tcatcgtatc atatttagct aaaacacgat catgcatctc ttgaagaaat 647040
tcatgtactc gtggtccatt agaaataatt tcatacatat gcggatcatt aataatggct 647100
ttatccattt tttcaaaatc tttagatatt tggttaataa catccatcct aaaaccatcg 647160
atacctttgt ctagccacca ctccatcatt ttatatactt catttctaac tttttcattt 647220
tcccaattca aatcaggttg ttcctttgta tataaatgta aataatacat ttctgtatct 647280
tcatcatatt gccaggctga tccctcaaaa accgattgct gaagattagg cggttgatca 647340
tttttcccct cacgccaaat ataataatca cgatactcat tatctttaga tttacggctt 647400
tcaacaaacc agcgatgctt aaatgaagta tgatttacaa ctagatccat aataattttt 647460
aaaccttttt gatgtgcttg tttcaataat tcttcaaaat cagccattgt tccaaaatca 647520
gccataatat cctgataatc actaatatca taaccattat cataatttgg tgattgatat 647580
actggacata accaaataac atcaacccct aaatttttaa tataatctaa acgactgata 647640
attccctgca agtctccaat cccatcgtta ttactatctt gaaaactccg cggataaatc 647700
tgataaacag cagcctcctg ccaccaactt ttttgcatta tccttcacct cttttatatt 647760
taaacataac aaaaggtcaa aatcttggcc cttttatact ataataggca aaattttaac 647820
cttttcgata ttttgaagga atatcgtgat aatattcttt aaatatttta ttaaatgctt 647880
tcacattttt aaacccatga tttaatgcaa tttcattaat tgtgagacta gtattcatca 647940
aatcattata agcatgattt aaacgaattt tattaatata agataataat gtaatccccg 648000
tcttttcctt aaacattctt gataaataaa cctcactaaa atgaaaatga ttagctaaaa 648060
tcgtcaaact caattcatca tcataatgct gttcaatata agtgacgatt tgtttaatta 648120
tcggtagttt cttttttgtg attgccaact tataaacact acattcttcc agcagcagct 648180
catatatttg catcattcga ttatgtataa ctaaagtttc ttgatcaaga tgatcaccta 648240
aataaataat tagctgttct aattgctctt gatcctttat taaagataaa tcaaattcac 648300
attgtaccag tttaaattca tcaaataact cagttgataa aagtaatgtt attattttcg 648360
tttgatcctc taaaaatctt aatctatgaa tactattact attaatcaat actaactgct 648420
tagtattaac aaacttcttt tccccattca ctgatagttc aaaagaacct tgattacaat 648480
aaattaactc tatttcgtca tgccaatgcg gcttcattac tttactgcga ttaaactgat 648540
gattccaaat cttaatagga tatttaaagc tagtttcaac aacttcatat aaatgctgca 648600
ttatcatgcc tcacaaaaag gattgcttag caatcctcat cttctttccc atcccaacaa 648660
tatgtacata atttacattt atctaaaccg attgattcga tcatgtcatc taaacgatga 648720
taacgcaatg atgtaaattt agagcggcga cgaatttcct cacacatatt tttatatctt 648780
tcactatctg ggtcagcgta ttcttttaaa atctcatcac taacattatc accttctagt 648840
ttttggataa cacgacgagt cactaaatct aattctgaac tagagcgtga aaaatttaaa 648900
tatttacacc cgaacatgat tgggggacag gcaggacgaa catgaacttc tttagcccca 648960
ctttcatata aaaattctgt tgtttcacct aattgtgttc cccgaacaat tgaatcatca 649020
atcaataata aacttttatt tttaattaat tctttaaccg gaattaattt catcttagca 649080
atcatatttc tttgactttg actagatggc ataaatgacc gtggccaagt cggtgtatat 649140
ttgataaatg gacgagcaaa gggaatacct gaaacatttg aataacctac tgcatgggca 649200
attcctgaat ccggtacccc agcaacgcta tctggctgta catcatcacg ttttgctaat 649260
aaattaccac aacgattacg catacattca acattgattc cctcataagt tgatgttgga 649320
tatccataat aaacccataa gaatgaacaa attttcattt tatctccagg accttgttta 649380
acttcaattt tacttggtgt catgaaaaca atttcccctg gtccaagatc acgataatga 649440
tgatatccta aatttaaaaa tgcactactt tcaaatgtcg cacaatatcc ttctggtttt 649500
tccccaataa tcactggtgt tcttcctaat ttatcacgtg aagcataaat tccttcagat 649560
gttaatatca taatactcat tgagccttta acaacgtctt gaacatattt aattccttct 649620
acgatactat ccttttgact aatcaatgcc gctactaatt ctgtaggatt gacttcaccc 649680
gaactcattt ccaagaaatg agttgcccct ttagcaaaac aatcatcttt taactcttcc 649740
aagttattaa ttctacctac tgttgtaatg gcaaaagatc ctacgtggga tctaaccaac 649800
aacggttgtg cttcattatc agaaatacaa ccaattccta agtttccttc aaattcttct 649860
atatcttttt caaatttagt tcgaaacggc gagttttgaa tgttatgaat cgatctttga 649920
aaaccattat ttccatgaac tgccattcct cctcgtcttg ttcctaaatg ggaatgataa 649980
tcaatcccaa aaaacaaatc taaaacgcaa ctttcttttg atgcaacacc aaaaaatcca 650040
ctcatttata tctatcctcc aaactttata cacccattgt atcttatttg taacaaattt 650100
cctatattta atcttatttt cgctaaaata ttgcccagga aataaagaaa aacctgttat 650160
aataacaggt aaaatatcaa aacatttgct tatcaatact attatctaca aattctaata 650220
aagaaataat tacttctttt aactcatttg acttctttaa agtttcttgg tcaaaatgtc 650280
tttccaaata atcatgacta ccataataga cttttaaact accaatagaa ttagtttcta 650340
gatcatttaa cccttcaaaa tcagctattt ctagattacc aaaaagctga taaacaagat 650400
ttcttgctac ttcatcatta gtttctttga ttttatcatc ttcttttaaa tactctgtcc 650460
tcattttata atgagacgct tctttcaaca acgttacatt cacgactatt ctatctgagg 650520
tttctaagca caaagaaatt agcttatgtt ctggcaacta aattcctcct tcactaatac 650580
taaattatat gaaaattata tcttattata ccccattagt tagataataa tcataaaaaa 650640
actaggtata agagtatacc tagtatcaaa tatatttcta tcctatcaat tcaatatttt 650700
tttaatctta ttttattagc tgctgactac ctttataaat ttcttgggtt atcaagatta 650760
tattctttag caattttttt gaaattatat aaaaggtagc gatgacgtac taaatcatcc 650820
ggcttactac gatacaatgt tacaattcca taaggatcct ccattacaat ttgatgattc 650880
tccaatgtat caaataaact taatgcattt ctttgattta acacttcaaa gcgacatata 650940
ttattatctt tagtaattat atctaaatca agataaaatc taaattctgg catcggccat 651000
gaaattattg atcttgaaca cattgagatt tttgtactct taatttcacc gtaaggaatt 651060
tcaatctcct cataattagt attattgaac ctgacagcat ccttatcgaa atttaaaaca 651120
cgattacgta atgcagacgc ttcatcatat tccaatccat caaaaattgc ataaacaatc 651180
aatcgtgcag tagtagattt tttgggctca aacgtctcaa cttttacttg actggtagta 651240
ttttcattct tcctatcttc tgttttttcg ccaacagaat tttttatttc cctctcttga 651300
aattcttttt tagattcctt tttaagatta ttttgaggat taaacaattt taataaacta 651360
tcctgtgttg ttatcttaac aatctcatta aaaaaatcaa cttgactgcc attttgacaa 651420
tcaatccgat taataatttg tccatcacgt aaataaagaa atttctttgc ataactggca 651480
atcatattat catgagttac taagataatt gaggttcctt gttgattcag ttctcttaag 651540
atttctagta cttcatgtga atttttagaa tccagattcc ctgttggttc atcacaaaca 651600
acaatttttg gcttcgttac tattgctcta gcaatagcaa cacgctgccg ttctccacca 651660
gaacattcat ttggcttttt atatagagta tggctaatat ttaagcgttc accaatctca 651720
ttaacgcgtt ccttaatttc ttgtggagaa acttcattta aaatcaaagg tgtagcaata 651780
ttgtcaaaaa cagataatga tggaactaaa ttgtgatttt gaaaaatgaa tcccaaatat 651840
cgattacgat agtcacttag ttcagcatca ttcatctcac cgacaaaacg attaaatatt 651900
ttaactgctc cactacttac ttcatctaat gttgataaac aatttaataa tgttgatttt 651960
ccggaaccac ttggccccat aacactaata aaatcccctt cctctaagat gaaatcgaca 652020
tttcgcaatg cataaaaatt agcgccacgt tttaataaaa tatcctgatc atatatttta 652080
ctaatattat tcgccgtgat taagatatct gacatcatcg tacacctcct tgattaattt 652140
acgataactg acgatcatat atattgacat aaatgtatat aaaataatat aaattgcaat 652200
cattgtgata aaagtattgt aagtaatcat attaactaaa taactttgat ataataagga 652260
tccatacata acaattggga atatcacaat taaaataata aacagcatca tctcttggta 652320
atgaatctta aaaatacttt ttttgttgta acctaaagcc cgcattgttg caattactga 652380
agctcgggtt ggcaaataga tcataaagcg aataataaaa caaaggaaca ttgacgccat 652440
taatgcaaaa aaactcatca tcattgcatt ttgcacgtca atcgaaactg actgcaagaa 652500
taagaaacta ataattattg gtacaacaac agctgaaata ttgatcattg ctgtcattac 652560
gtcagtaaga tcttttagat tactaagtga tatgatccag ttctttgatt ttagtaagac 652620
tttattatgc aataagtcaa ataataaagg aaatgtatta tcaatgatga ggacctcacc 652680
taataatgaa aaagcaaaat aagtaggtaa attattattt tcaattgatc ttaacattgg 652740
cgtaaaacct atatatatta gtaatattcc tagtattgtt gataatattt ttccttttgg 652800
aagcatatca atagtttttg gcttttcccc ctttaaagct aaaccacttg acattaattt 652860
aaatggatta aaattagttg tttttcgtgg cacatgattc atatagccag caatatcagt 652920
tttgatcctc ataaattttc ccatatcaat aacgaccaca tagatcattt ttgttaagaa 652980
taaagcgcca taaataatta aaatattcgt taggtcaact gtaatcacag catcataaat 653040
agcactatac atataaaccc aaccccagcc aattaaaaat ccaagcgcat aggaaattag 653100
aaatagcaat ccaaattgaa ttaaaatata gcgaattatc tgcttcatat ttcgaccaca 653160
aagcagtaat aatgaaaact cctcgttttt attattaata atgtaattat tcacaaacaa 653220
ggtcaatgca aatgcaatca tgattacaat tcctgtgact aactgcagaa tatagccatt 653280
tgcaaaatcc acttcaatat tactagttga atacatcaca accgaaatga attcgaatga 653340
tgataacagt gataaaactg ctaatatccc taaatacagt tttttctgcc cggaaataat 653400
ttttttaata aatgtaatca tttccaaatc ctcccttcac taaattcttt atctacttta 653460
agtatacgct tacatttttt aaattacaaa tattattata attattttta agtgaataac 653520
tattatttat attaatcata tgtaaaaaaa gtaattaaat tcatctttta ataaaacagc 653580
ccctacaaat gatacatatc attcatatgg gctaactatt tttatcaatc aatttttcat 653640
attcatttat aggcattggt ttatagtaca catatccctg aaccaaatca catcctactt 653700
cacgcaaaaa ttctacctgc gaaacttgtt ctacaccttc agcaaccgtt ttaattccta 653760
aattattgac catcttaata atatctttaa taattaattt aactttatcc ggattatctg 653820
aatcttcaaa aaaagcacta tccaacttta aaacatctat tggtagatct ttcaataaat 653880
ttaatgaaga atacgctttt ccaaaatcat ccatagaaca aataaaacca taatttctta 653940
aatcattaat aattttaatt agtaaatctg ttctttcaaa agcaacactt tcagtgaatt 654000
ctatctcaat cattcgatcg ggaataccaa attcttgttt tatttggtaa tactcattca 654060
caaatttaga attgtaaaac tgcactttag atacattaac cgaaacagga taacatggta 654120
actcttcatc aattcgtttt ctaatccagc tacaaacttc acgatataca tatttatcta 654180
tctccttaat atgcatattt ttttcaaaaa tagggatgaa cagatcggga taaatcaatc 654240
tatcttcact cttccagcga actaatgctt ctgcacatgc gattttacca gttttaatat 654300
tgactttagg ttgcaaatat acaagaaatt cttgattgtc taaagctgtt tgcatcctat 654360
tttcaatcat tttctccata tgcaatttat ttctaattgc ttcagtataa aaagcatagt 654420
gttcttcaga agttcttttt atagtatctt gagcaaaaat agcacgatca atgtactcat 654480
cgatagtaag tttttcaata acatcttcat aacagcaaat accacaacaa agcctgattt 654540
gataaccatt ctttgctttc tttacataat caatcaaaat ttgatcaatt tctatttgtt 654600
tttgttttaa catttcttta ctctcataat gacgcaatat aataaaacta tcagcattat 654660
ttcgagcaaa agtttcattt ttatcaatac tatttgctaa tacagctgca tactttttta 654720
atattttatc accaaattga tatccaaaga catcattaat atacttaaaa tgctctatat 654780
caatatacaa aaaagcaaat tgaccttttg ttttcttaat aatatttctt gcctctaaaa 654840
caaatttaag tcgattattt accccggtca agttatcacg gtaagctacg atactcaaag 654900
tattattttt gcgttgcaat gttatcatgc ttcgtaaata aaaaataatt attatagacc 654960
atgtcactaa tgaaattcct gataaaatca tcaacatcat taatagataa ttactttgtg 655020
tcgtagtata atagtcaact gcaaagacag tatcgtttgc tatctcaaat aaatcttcac 655080
tatcactaag cagtttctca tgaccatttc cttcgcgtac tagaactata tccatttgga 655140
ttgcttccca aatatttttt aatttattta aatctgtccg gtaatcttca tcatcaagat 655200
taattagact atatttacca actcccatat ctaactctgt aagaatctca tcaatataat 655260
cttttaattc gtcatttggc tgatcagtta attctaattt gaccaaacgc tggctcgcac 655320
cacgaacaat cccaacataa ttaatcaatg tcccataatc acgaatttta tataaagtgt 655380
gaactgatat tgagcataat agtattaatg ttaataaaaa agcgggtaac cccaatctct 655440
ttagtctcat ctctatcaca ccctatcacc ttaatgatat gctaatcatt aggataaaac 655500
aagcaaatgc cctcattttt acattttttg taaaacgctt acatttttat caagtgattt 655560
acacaagaaa agatttaaat atcaaatttt tacttttata atacaattaa catatatgtt 655620
taaaacaact agttgcaaaa tatgattgaa tggagaatat catgaaaaca agaaacttaa 655680
tcgcaacatc atcattagca cttacaatga tgctaggaat agttgccacc cctttatcag 655740
cacaacaaac atacacaccc ggtgtgacgg tagagaaaaa tactaatcca aaatgggaag 655800
cagactatac agcaaccttc atttacaaag ataaagatgc gcgtgatgca acaaatgtta 655860
gcgtaagcgg tggtttccaa ttttataaac ccgaagaagt acagtcattt gcaaatactg 655920
gtgacggggc taatatccca tgttataatg cttatcaata tcaagatgga atgttcgctg 655980
gagggtacaa tcttaatggt gatgccgcaa attattcaat gactgaaatt gaagatgaaa 656040
tctttgaggt aacgatccct ttacctgcaa atgaatactt ttatgctttc aatattgaat 656100
attcagatgg cagtagtgaa actaatgtca aagatcctgc taatcccgca cttgctaatg 656160
atggttcaga tgctggatgg agcctatttt atgtaggtaa tggtgagact aaaggacaag 656220
aatatatcag ccctcgtacc gatggtaaaa caggtactta ctcatttgtc aattatttag 656280
ctgaagatgg aactactcaa cctttaggaa tctatctacc gaatggttat gatgctaata 656340
aaacatataa aacaatctat gtttctcacg gtggcggggg taatgaggta gaatggatga 656400
ctattggtgc agttccaaat atcatggata atttaattgc tgatagttta actaaagaag 656460
caattgttgt tacaatggat aatacatact tcaattggga ctatgatcgt attattaata 656520
acctatttaa taatattttg ccttatatcg aaacacatta caatgtatca aaagaagtaa 656580
acgatcgggc attttgtgga ttatcaatgg gatctatgac aactacgact ttataccaga 656640
cccatcctga tcaatttgga tattttggct gcttttcagg agctaatgtt ccagttgatg 656700
taagtaaagt tgcacatctt gatcaaccaa acttatatat tactgctggc tgcatcgata 656760
tggccttaat gaatgatagt tataatactg cgagcgatcg tactacaact ggattcgtag 656820
ataagctaaa tacattaaat ctaaccaatt acaaattaga aattttaaat ggtgctcatg 656880
actggtacgt ttggcgtgaa tcgttcacta actttgtaaa agatcacttg tggactaaag 656940
atgttaagat agaaacgcct agtgaaactc ctgttattaa accagaaaca cctgcttcat 657000
caacaaatac tactactgca cctaaaacag gtgacgattt aaatcttgct gttgctggat 657060
tatttatcat catctcagtg acaactggtg tagttataaa aaaacattac taaatacaat 657120
aaaaatcgta agttcatgat atctcttaac aaaaaagata tcaaacttac gattttttta 657180
ttactcgtac tttataaatt aattcagaaa taatttgact taaataaaat aacgaataat 657240
agccatcatt aattgattta ggaatgccat attgataaat ataatcaaat attttctgct 657300
cagctaaatc atcttgagca aaaacaacaa gttttaaatt cttctgactc gctttctcta 657360
ctactcgttt ttgaatttca ctataaaaat cattggacac atttaacaaa accaaagtat 657420
ctccatcttt aaaaaaatca ctatgaatat cttgaaattc ctgtaaatca aataaatatg 657480
caggaacttc attcgccacc aaatctaact gcacagtata aaagtcaatc atttcatgag 657540
tatcaccaat aaatgtaaca ctacggctat taagcaataa tttggttata gcaacaagtt 657600
tttccatgtc caaattaagt tttgtctgac gaagattgct gatagcttca acatataaag 657660
aatcagctaa attatccaat gatgtacgca taaactgctg catattagat accgttctta 657720
ccatatttaa attacgaata aaatagtcta aaccatcttt aaaatcctgg aaagaactgt 657780
atcctatctt ttgaacaaag cgactaaccg aagcaataga aatatttgct tcttgagcaa 657840
tctgctctaa tgaaacggtt ttaatatcac caatatgttc aatgataatt ctagcaatat 657900
tgtattcatt agtattagaa agattttcat tacaatatct aaaaaaatta aatcccaact 657960
gctcgtgtct cttcataaat tccctccatt ttttatatta tatcaattaa atatcttaat 658020
taaaaggaat tctctttaaa tgtctagaca cataaaaata accgggaccg gttattttta 658080
taaagacata cttttacggt caaaaattat tccacctccc ccataacaaa caatcattac 658140
tacaagtaat cctcctaaca ttaaataacc ttcattatta ccgttaatca atttttgagg 658200
atcaaataaa gttaataatg ttgcaaattt aagtccttcc atacttcctt gcatattcga 658260
aagcatttga atcataataa aaactatcgg gattcccgct ccaaataacg atgctaagcg 658320
gtactcatta aaaatacaag aacacatata acaaattcct gttaatgtta actgtaaaat 658380
gaaaactcct aaatttaaaa ccaaataagc tccaatatcc aaatcaccag gaaacatcaa 658440
agcactacat ccaagcccta aacctgtaca aaaagcaatt aaaacaaata agtttgttat 658500
gataaccagc atttgtgtaa accacacaga tctactctca acgccactac ataataaata 658560
actcatcaca ccattatcaa cttttcgaac aactaaacgt aatgctagta aaattccaaa 658620
aatcaaagga aaaacaatca tgattaaacc atataaataa gtagagagaa aatcaatcag 658680
tgttgtcggg gtaccactca ttcctaccat tgccattatt tcaggcatac ttttagcaaa 658740
tgtttctagc gctgttccta gcttaggatc atacattgct aacatgatcg ttgtatacat 658800
tgtcaaaatc aaacaaaaaa taactagtat cttataatta gatttccatt ctaatttaaa 658860
tagcgcttta ttgaacatgt tgatttcctc cataaaattg cataaaaatt tcttctaaac 658920
tttggtgtgc aatatcaaaa ttcattaatt cgtagttatt taaacaactg atcaattcat 658980
taatttcatg ctttattaca acctcaacaa cattatcatc agcatttcta attgtaaaag 659040
attctttttg aaatttgtaa gcatcttgat gatttttaaa tgttattata tatatctttt 659100
gtttcgattt ctttaatgtg tcaatatcct caatactcac cattcgtcct tgacgaataa 659160
ttcctacccg atcacatgtt ttctctactt cttcaaacat atgtgaggac atcaaaatag 659220
tcttaccacg cttcttttct tcaataatta aattaataaa ctcactttgc attaaaggat 659280
caagtccact agttggctca tctaaaataa aaacagctgg atcatgcata aaagctacta 659340
ccaaacctat cttttgtttc atcccttttg acatcttttt gatttttaca tgaggatcaa 659400
gatcaaagcg ttcaattatt tcttcagcac gccccaaatc cttcattccc cgatactcag 659460
ccataaattt aataaactga attccagtaa cctcctccat taaattaatt tctcctggaa 659520
tataaccaat cttcttttga atctctgcaa ttttcttact acaatccatc ccttcaatta 659580
aacaggttcc ttctttagga ataataaacc ctaacaaatg tctaattgtt gtagtttttc 659640
cagcaccatt aggtcctaaa aagccaaaaa cttcaccttt ttcgatttta aaagagacat 659700
caaatattcc tttatcatta ccataatctt ttgttaaacc attaatctca acaacactca 659760
tataaattcc tcccgataga aattctcttt tataatatcc aaatatctaa aatactcatc 659820
ttgaatctct ttcatattaa cattttctaa atcctgatat ctatccatat atccttgcga 659880
catccaataa attatgttcc aaacttcttc aggatcaact cctgctttaa acttactaat 659940
atcagcacgt ttaattaaat tatatgatgc tattacctct gcatataatt gttcataact 660000
atttcctact atttccttac gattttggta atagcgcagt gaaaagccat aaatatatgg 660060
atatttagac atcatttcca ttttgcctaa cactgctaat ttaattgcat caaaaaaatc 660120
tttaccatct ataatattca ttttttcaaa taacttcatc actagtctag cgctatattg 660180
tgctaagtac tgatacaact ctagtttatt gtgaaaataa taaaacaata gtccctttga 660240
tattcccgct ttggctgcaa tatcatcggt taatgcatgt ttataatcat ttttactaaa 660300
tacttctaac cctgcattaa taatggccag tcttttttct tcgtttaatt caaagaattt 660360
ttggttcatt ttatcacccc tttgactgac ttgattaatt aaattatagc aaattgactc 660420
gtttcaacaa cccctcgtat caatctttat gcaatcttaa tagtccaaaa aataaagacc 660480
aaaatgaaat attttgatct tttcatcatc ctatcttact aaactcttag ctaaccaaat 660540
atctggtttt cctaaaccat tggcatcagg aatcacccca actatttgat atcctatctt 660600
ttgataaaac tcatagggat gtcgttcaag attcctaata ttttttatct ttgaatatag 660660
atcatcaaat aaattagtat tagccaatgt tgttttatca aattcatcat cactgcctaa 660720
ataaatggta cagcagccac aattcttaag ctcattttct aatgctgtac aaagctttgt 660780
accaatacct tgaccttgcc actttttaga aaccgccaaa ggatgcaatt cccaagcagt 660840
gattccatac tggggaatag ccccaaccaa ccccatcaat atatcatttt caactgcccc 660900
cagcattatt ctatttgtcg ataaacattt tgttatttct agctcggcac aatctttata 660960
tgcatatgga aatgcttcaa tcaataatgt agctgcctgc tgacgataat aggttaaatt 661020
agatgttaac ttaattattt ccatattttc acccctttta cttatataat accatctatt 661080
ttactttaag ctgcttaatt cttattttta tattattaat aatataaaaa taggctgtaa 661140
ctaaatagaa taaatttatt ctagaggggt tatacctctt ttttatttca actgtttttg 661200
gatattcata aatgtaatgt aaatatcttt atttttaact attataaata attatttctc 661260
ttttcgatac tttctatgtt ggttttcaag aaatgtgata ctagaataaa aactgtacca 661320
gttaaatgaa aaaaagcaat cagcccttca tgcctacaaa gctcatatca ctttcctttc 661380
ttaatagaac tgctagctat catatagatt tacctcaaaa gtattctaac aaagagtcca 661440
gtttttagct atttaaaata cttatttatt aaatcattta tatacatatc accccaatat 661500
catatttcct gcaaaacagg cattaaagac tcccccgctt tgaaagatag tattctactt 661560
ttggagaaat ttaaggatat tcttttctta taatgaaata atcagcctcg agttctttta 661620
attgtgtact taacattttg tgtgatatag tccccaatgg acgttttaat tcactatatc 661680
gcattaattc agttttccaa agctaaaata aaatattcat cttctatttg ccacctataa 661740
ttgacattgt atattcaaga tggttttgaa ttaactgctc catttgttta catctatact 661800
tattttttct tccattttaa actctccttt tagatagtat cttacctaaa agtgcatact 661860
gttatttttg ttaaggtagt gctatattac acttaataaa aagaaaaaag gagtaatgat 661920
gatgagaaat ttagataaat caatttcaat caacggattg acgttaaaaa acagattagt 661980
aatgccccca atggcaacat caagtgctaa tgatggtgaa gtaagtcaaa gaattcttga 662040
ttattatgat aagaaaacaa aaggtggata tattggatta gtcattactg aacacagtta 662100
cattgatatt caaggaatgg ccaatcctaa acaaatgtca gtagcaaagg atagcgatat 662160
aaaaggatta aagcaattgg taaatataat tcataacaat ggaagcaagg cgtttgctca 662220
aataaatcat gccggttcaa tggcaagagg aacaggatta cctactgtta gtgcaagtaa 662280
tacaatacca ataacaatga aagaatccaa tatcgaaata ccagaagaat tgagtaaaga 662340
acagattcaa tatatagtaa aaagatttgc tgatgcagcc agacgcgtaa agttagcagg 662400
ttttgatggg gtagaaattc attctgcaca tgcatatctt ttaaatcagt tctattcgcc 662460
aataaccaat catagaacag atgaatatac tggtacaaca cttgaaggtc gattgagaat 662520
tcataaggaa gttattgaag cagttcgaag tgaagttgga gaagacttcc caattgcttt 662580
acgcttaggt gggtgtgatt atatggctgg cggctcaaca attgaagatt ccattaaagc 662640
ctctcaaatg cttgaaagtt atggtgtaga tatccttgat ataactggtg gaataaatcg 662700
ctatatgatt ccatggaata aagagccagg atatttttca gatatgacag agcatattat 662760
ggaaaaagtt tctattccag ttattttgac aggtggaata actaatgcca tggatgctga 662820
aaaactactg caattaaaca aagcagattt aattggtgtt ggtagagcta ttctaaaaga 662880
tgatagttgg gcaaaaaatg caatggaaca aaaataatgc aaatactggt atctataata 662940
caagtatttg ttgaattacg atacaataaa ttcggagatg aatactatct ccggaaatgc 663000
ggcaatgacc tctaaaaaat ttaaaaagaa agtaagaaaa gtttccaaga agttaggaaa 663060
aattgcctaa aacttatatt taaaaccatt tttaagatgg taattcttct ttaccatatc 663120
atatttatta ttaatttaaa atgtattttg aaattataaa atttattaca attaaaaaca 663180
gataaatttg tatgtaccta agaaaaacat tattcattaa tatattagaa aaattataaa 663240
ggagaagata catacctttt atatggggct ttgaatataa tggggaattg attacttgtt 663300
tgaaatcaca tgccataaga tttataagat aataaaaata atgtattttt aagtatatat 663360
tttgatattt aatcttattt aaaatataga ttacagtgta tatgaatagc gatacagctg 663420
ataaacaatt atttcttgga ttttgggatt aatataataa ctatcttttt cttttgtgag 663480
taaggtagtt attttttcta taattatctc aaagagtaat gttaccacta tcgctataat 663540
tacgattttt tgatattatt ttcactatat aatttctaaa taatcaaaaa agacaagaaa 663600
taaataccat gctataataa gtactgaaaa agtttaaatt gtaatgtaag tttactattt 663660
taattttgga aaattattca gtatatttgg gacataataa tataatggga tatattttta 663720
tcaattgcta tagtattttt taaaaggagg taaaaatgaa attaatatta agtgataaat 663780
atctaaatct tgacgtatca gatcattcta atacaaaatt tatagatcta tcatcattaa 663840
atatagctaa ctgcactgga tgctttggct gttggactaa gacaccgggg aaatgtgtta 663900
tacgtgacga tgcaacaaaa gtatatccgt acattgccaa gagtgataat ttaatttata 663960
tcagtaaaat attatatggt ggttatgata cccctatgaa gacaatgctt gaacgtgcaa 664020
ttccgattca aaaggcattt attagaatac taaacggaga aacacatcat gttcaaagaa 664080
gtgtagaatt gaaaaatgct acaattattg cctatggaga aatagacact gaagaaaaag 664140
agatatttaa agctctggtt gaaagaaatg ctaaaaacat gaattttaaa cactataaaa 664200
tattatttac aaatgaacaa aacctagaaa aaactgtgaa aacggagatg ataaaatgga 664260
gcgaatagtg atattaaacg gaagtccgcg agcacctaaa tcaaattcta aatgttatgc 664320
agacattttt tcaaaaaaat ataataaaga cattgaatat tacaatataa caaagcaaaa 664380
tcatgataaa ttatgttcta aaatgaatga tttctccgat atgttactgg tttttccatt 664440
atatgctgac gggattcctg ctacactttt aaattttctt aaaagtcttg aaaacaactt 664500
accagataaa aaaccagtaa tttcagtaat aataaattgt ggatttttag aatatacaca 664560
aaatgattta gcagttaaaa tgatagagct gttttgtaag aaaacaaatt gtgagtttgg 664620
atctgtttta aaaattggta gtggagaagc aatcctaaaa acccctttca aaatatttgt 664680
aacaagaaaa gtaaagaaat tagcaaattc aatcctatca aaaaactata aaacactcca 664740
tataacaatg ccgctcaccc caaaattatt tattaaagca tcaacaaaat attggattaa 664800
atatggaaac agaaatggta tcacaaaaga acaaatggat acaatgagta tagaggatga 664860
caatacctta gtttaacagc tatatcaaaa aggagctctt atgattttaa atgtagttag 664920
ttttgatgaa gctgcgctcc atgttctttt atactagcaa ttattcatat attgtgtttt 664980
tggatagaag tttagagtgt ttatcgagag ctcaactaga ttatatttta catcaagtcc 665040
aaacagccca actaatttca atatcttctg ttttagaatt ttagtcccat tttctattag 665100
ctaatcttta tttgaaaatc tcggagcatc atccttagca tctatttgaa ctttttgtac 665160
aaaataatca ttattttcat ctattaaatc aacaataaaa ttatatattc catcattata 665220
ctcagtaata ttctttttaa tagctttatg cattaaagaa aagaactcaa tatagcttat 665280
atttgcagta agtattaatc ctatacaatc ctctatattg tttttttgta ttatgtatgc 665340
ctacaaaact catattgcta caatcctttt ttaataaata atcagctgca tacattatat 665400
taccgccaat tgtattctat caaaatatgt atttatttac tgcttttaga atattaaaac 665460
aaaaaatctc tttagttttg tttatctaaa gagaaatttt atattataaa aatgttagca 665520
aattttaaag atgcttttgc agcagatata acaatcataa tattttttct ttatctgtaa 665580
gctagattaa tataatatat ggaatgataa ctactatttt atactattca gttctatctt 665640
agtattccat atcgatgata gtcaaattag tctgaatctg atgatttcaa acaatgtcaa 665700
actgcaacat ttttaaaatt gtcatatgca ttaaattata tatcatttat tatcatacct 665760
aaagacattc ttcgtcaaaa tgataaatcc ttaattgatt ttacacaact ttttgatatc 665820
atgcattaaa taatccttct ctattagagg cttgaatata tttaaaatat tatcatctaa 665880
tttattcaaa atctgaatat agataattgg atgatagtca gcaaacataa tagttgatgg 665940
attatttttt atgagtgaca aaattgcatt gagatttcca tctgaaatat caatactatg 666000
ttttgtgcaa atcaatctta aatcttcaaa agacatttct tgtatcttgt gattaattgt 666060
ttttatggta tcattcataa acatcatacc tccttgcaat agcagtgcaa cgaaaatgtc 666120
tttatacttt aattatacta atattcaata agttgtaaat ttatataata agattttgtt 666180
tgatattcaa aacaaaatta tcaaaataga attaagaaat atatataaag aaaataattt 666240
taccaatacc atcaaattaa gatgacaaca ttttaattca aaggaattat ctaaaattaa 666300
ttgcattgaa ttgttatttt tttataaaaa aacatatgat aaaaagtggc tgtaatgatt 666360
gtgtagtttt ttagctattt tagagtatta cagttctttt tttgtaaatt aaaataaatg 666420
ataaaatttt agccttttta ctctgtcttt tcctcattaa tttactgttt tttgacgcat 666480
tttaaaagaa ttaccttatt tttgaaaaaa tttatatctc taattttaca cctgctggtg 666540
ttcttttagg aagctttcca tagattgctt catatttttc atcgatggta tatatgtttt 666600
taaatcatta ccgttacgct gatatatata attcttataa ttccatcact tatcccaaat 666660
tggatattat attcagattt aaatacattt gtatgcttat agtaatcgta ttttatatgc 666720
ataaatgtta catcaagatc tattttgaaa cagctgttac ggtttcccgg catatctata 666780
tgaatagtat attcccatca aacattttgt gataaaaaca gattggttgg attaaactat 666840
tgcgtcacag gcaacgtgca taacagtgta tcgtttttcc aacgtatgcg ttactaaatg 666900
aagaatataa agataggaca aaaaatatat gtttaaatcc agaatatatc acactgacaa 666960
tttgtaagac gatattagaa aacaaacaaa agatgtatgc accatataaa agatcaatca 667020
caaaaaaagc tacattaaaa aatatgaata tgtatgtccc aacataaaga ttttagaata 667080
cagcgctaca aataagttag gatataggaa atacaaatta aatccataga attgcaaaaa 667140
acatcacaat ttgagatata caagagtaaa aaggtcttaa ggagaatcag catcaaggac 667200
taatgatttt tgcgtatcac attctaaaaa taatagcaag ataggggaac aacactgtat 667260
gtaatccaaa aacgctattt ttctataagt tagtcaatat aaaaaaagcg atactcgttt 667320
tggagtatca ctttgtcaaa agtctgaaaa agcgttcatc atagagtgct ttttgcacaa 667380
gacaaaacca caacataatt atttacccgt tacagcctct ttcttaatat ttctatattc 667440
tttaatgtat ggatcccgat aaaaagaata agctaactgt aaacacatac aacaccaaat 667500
taccggttca caaataataa ccccaaaata tcctaacaat ggaataaaca gccaaacaaa 667560
tactattttc ccaataaatt caattatgct tgaaactaaa ggaataatct tacgccccaa 667620
tccctgtaaa gaatttctaa gattcaataa gattcctaac atacaataaa atggagcatt 667680
tagcattaaa tataatgaac cattatcaat tactactgca ctacttgacc ctgacaataa 667740
ttgaactaga gttggggcaa taaagaataa tacaactgtt gcaataacac tccaccctac 667800
tgcaattaaa ttagcataac ggaccccttg tcgaattcgc aatccttgat ttgccccttt 667860
attttgtgaa acaaaagtag atagggctag acccaatgtt gctgcaggca tcatacaaaa 667920
actatttaat ttacgagcag taacatgtcc agcaataatt aaataaccaa atttgttgat 667980
ggcggtttgc aaaataacag ttcctgtaga aacaatcgac atcattaatc ccatcgaaaa 668040
accttgccct gccaattctt gatatagttc cctgctaatt ttaaaatgct ctttgtgagg 668100
aagcaaaata ggacattttt tataaatata ataaaaacaa agaattgccg aaactccttg 668160
agcaataaca gttgcaatag cagcaccttg aattcccata ttaaattgag taataaataa 668220
taaatctaat cctacattca agactgaaga aataagtaaa aaaacaagcg gcattacact 668280
attgccaatt gctcgcaata atccagcaca caaattataa gcaaacatta ccccaacaaa 668340
aatagtaatc ataaaaatat aatcatatgc ctcattaatt atatttgctg gtgtatttaa 668400
taattctaat agcggatata aacaaaactg tgaaaaaagc attaaaataa tagttaacaa 668460
gattcctatt acgattgatc ccgcaactga tttttttaac aagttctcat ctttagcacc 668520
aaaacttcgt gctgtaacaa tacttaatcc atttcctacc cctaaagcaa aaccaactaa 668580
taattcataa atagcaccac atgctccaat tgccgccaat gatgtatccc ctaaaaagtt 668640
tcctacgatc atcgtatcca tggtattgta aagttgttga aaaacattag ccacaaataa 668700
tggaaacgca aagatcaaca atgattttaa aattggatct ttggttaaat caactttcat 668760
tttaaacata attttccctc ttttatctat tataactcat attattgtat tcctattatc 668820
gccacttttc aacaatatcc cttttcaaag aatgaaaaaa ccaagttaac acttggttta 668880
taatgtcgca ataaaatctt ttaatatttc gtaacaattt acaaatgatg caacttccat 668940
acgttcatct ggagtgtgga tgtctgccat attaggaccc atcgtaataa tatctagcgc 669000
tggcatcttt cctttaaaga ttcccgtttc tagtccacca tgagtagcta cttcttttac 669060
ttctgctcca gtacgtttaa aataaaatac tttaaataaa tcacgtaatt ttgaatgttg 669120
gtcgtaattc caaccaggat aataatttgc tggagtaatt gtgccaccaa aggcatctgc 669180
aataatatct aattcatcaa ccatgttcat cacagcgctt ttcattggtg aacgtagtaa 669240
ataatctatt tttaattgtt tatctttaat tgatactaca cccatattta atgaaaccgt 669300
tgtcaaatct tcaatcacta atgaacgttc gacaaaacca ctcttagctg ccatcattaa 669360
ttttataata tcttttgatt cttttatact caacgtttgc tgtgcaatat cattatttaa 669420
tgataactca actttaacac caggatcact aatttcaaat tcttcactaa aataatcttg 669480
atactcatct gccacttcct gaagtaactt aaaatcactt gtactagcaa aaacaattgc 669540
acattcacgg ggaatcgcat tattttttaa tccaccattt agatccacta gctggatatc 669600
taaatttgcc ttgatcatac catacataac tcgagcagcc aatttattgg catttccttt 669660
accgcgatga atttcacctc cagaatgtcc tcctgataat ccttttatta ataatgtata 669720
agttggattt tcattactag taaaatataa ttccttagta atcattacat cacagcctcc 669780
tgatgaagtt gtgcaaattt ctccttcatt ttcactatct agcccaatca ttcttgtcgc 669840
ctttaataaa cttgcatcaa aacctaacgc tccatcaaga ccaacttctt cggcaactgt 669900
aaaaacacac tctaaaggtg gatttttaac attaggatca cttaagattg ccaacatata 669960
agcaactcca tagccatcat ctgctcctaa tgtcgtccca ttagcactaa catagccatc 670020
ttcaagatac aaatctaatg gatcatgttc aaaatcatga ttactatctt tattcttttc 670080
attgaccata tccatatgtg cttccaacat cagtgtttca tgattttcat atccttgact 670140
agcttctttg taaataacaa tattatttaa gtgatcccga tgatatctaa aacctttttc 670200
tttcgcgaat gcttcaacaa agtcagcaat cttttcttca ttataagagc catggggaat 670260
tttacaaatt tcctcaaaat aataattaac taaaatctct gtgtctaaaa cagccattat 670320
acctaacctc cattttcact atttttatta taacaaaatg tttaactaat taacaaatca 670380
aattaaatga tgtataataa tattattaaa ggactttaat aattatttta atttagatta 670440
acctgtcatt aaatatcaca atcatgtata gcttttagga ggactagcca atgaaaagac 670500
aggcattaat actaagcagt atttatttga ttataatgtg tctaggttat atttggtgct 670560
atcctttttt caaaatagaa acaattcttt ttgatttgat ctttagaaca gttttatggt 670620
caatatctag ctatggatta tatattgtct tgctaatact aaaaaaaatt cagtttgtta 670680
aaaaacattg ccattagcaa accattttta ataacctgcc tcccttacat ttatttaatt 670740
atatttcttg tagaaggatt cattggttta gtaatggttt ttgtttttaa aacatatgtt 670800
tttgcttact cttttttctc aatattaact atcctccatg caatcaaatt atctcaagat 670860
cttctcaaca attattgtac ttattaataa tgcaggagtg gcggaatggc agacgcgcta 670920
gtttcaggtt ctagtgagat tttctcgtgt gggttcaagt cccatttcct gtaccataat 670980
taatttaaag tttgtcgatt gttatctaca aacttttttg tatttattta atagcctaaa 671040
gccccctgct aaactcacac taaagtgaaa aaacttttac tctaggttac tatctgatag 671100
aatataagaa aagcgaggta aataaatatg attagaacac gaagatcagc cttcttaaaa 671160
tagaaaaact aactatatat aaatcaagga attttaggaa catataaaac aatgaatcta 671220
agttatacta tttttcattt cgacgatgaa actttttcta tcctatggag tgaatataat 671280
tataaattta aatatttcta tccaaattac ttaaataatc ttaaaactta cggtgaaatt 671340
aaaaaatatt tcctaaacaa gaatctgtta attcatttaa cttttcctgt ccaccctagg 671400
taacattcaa tgagtttttt taacaattaa tgataagcca cattacttat taccaatttt 671460
cgcaattggt aaatactaca aacaaaatga taaaactctt ctatcactat caattagagt 671520
acatcatcaa ttatgtggtg cttaccatgt ttctcatttt attaatgaat tacaaattat 671580
gattaatgaa cataaattta taaaggaata atgatatgat tgaaattaat aaaaaactag 671640
tacaaaactt aattaatgaa caatttcctc aatggaaaga tttagtaatt gaaccagtcg 671700
ctaaaagcgg acatgataat cgaacatttc atttaggatc aaagatgact gtccgtttgc 671760
ctagtggtaa aggctatgca gcccaagttg aaaaagaact tacatggcta ccttatctcc 671820
aaaaacattt aaccatgaca atttcttcgc caatagctaa aggttatcca agctgtggat 671880
atccattttc ttggtcaatc aacaaatata tagaaggtga tactttaaca aagcaaaaca 671940
ttaataattt aaatgaattt gctgatgacc tagctaaatt cttaaaagaa tttcagaaaa 672000
ttgatacaac caatggtcct caagcaggac ttcacaacta ttatcgtggt ggttatctag 672060
cagtatatca caatgaaaca atcgaagctt tagaaaatct taaaaccgtt ttaccaactg 672120
agctgctact gaaaatctgg caacgtgccc ttaatgcatc agtatctgat ttaaatgttt 672180
gggttcatgg cgatatagcc cctggcaatt tacttgttaa aaatggtaaa ttagcagcag 672240
taattgattt tggtgtttta ggtgttggag atccttcttg tgattatgca atggcttgga 672300
ctttttttga agaagaaagc cgacagcgat tcttaaaaaa actagatcaa gggatgattg 672360
atcgtgcttg tggctgggct ttatggaagg ccctgatcac atataatagc gatgaagcag 672420
aacgtgcgga aaatgctcaa tatacaatca atgaaattat taaagatgaa aaaaaacttg 672480
gttaaatcca agttttttta tcctttttgt tcaattttat ctaatgcttt aataacatcc 672540
caacaaaaat tatttggttg tgctaattct acgaaatgat gtcgcttgaa ttgtttcatt 672600
acattttttt ggactccagc aaataaaaca ttaatattat tttggcgaca taattctact 672660
acatcaataa actcccggat ccctgaatca tcgattgaag gtacaccacg cattgaaaaa 672720
ataatattat tacattcatt taaaatctca ttaacttttg taattatttg ttcttgattt 672780
ccaaaaaaca atggaccagc catataaatt actttagtcc tttgatgatc ataatttaac 672840
tccttatcaa gtcgttgtgg ttcaatatca cttgtttcaa tatctaaatc agaattattg 672900
attacaaata aaatcataga tataaacact ccaattacaa ttgcaactgt caagtcaaat 672960
acaacggtcg ctaacattgt tactaagaat tgtgtcatac ttgtttttat tcgtttcgaa 673020
aaaaattgtt taatttcatg ccattcattc attttccagg cggtcataat taacacaccg 673080
gctaaagctg ataaaggaat tcttgacata aatggaccta aaacaaacat tgaaattagt 673140
aaagccgctg catgaaaaat actaactaaa cgcgtttgac cgccagcttt aatcgcaaca 673200
ctcgttctag caatagcagc tgtagcagga acacctccaa aaaaaggaat aaccatatta 673260
ccaatccctt gtgcaaaaag ttcttgatca gcatttaact tttcattttt catttttcca 673320
gcactagcac cgcataaaag tgattcaatc attcctaaca tagcaatact aaatgcagga 673380
ataattagat ttgttattgc tgttaaattt aaactattca atgacaaacg agctttaggc 673440
aataatgtag atggaatact cccgacctct gctacattaa atttaaatac taaattaata 673500
atcaaagcaa taataattcc agctaatgaa gccggaaata tatttcccca ttttttaggc 673560
cataaaataa taattgctat tactagtatc ccaaaaaaca gtgcctctaa atttacatta 673620
aagcctaaca tacgataaga taagattttt tcaatcggat tgcttccttt cgaagtaact 673680
ccaaaaaaat tatcaatttg tccagttgca ataattattg cgattccact cgtaaatcca 673740
gtaattacac tagctggtat aaatgatact atcttaccaa acttaaataa tgaagcaatt 673800
aataacatta ccccagaaat aaaactagca acaaacaccc cctgtaaacc atatgtagtt 673860
gacaatccaa ttaaaattgc tgacattgct ccagttggtc cagaaatttg atacgatgcc 673920
ccagataagc caccgatcaa taatcctgct ataatcgctg taatcaaacc agccccagca 673980
tcagcaccac tactcacccc aaaagccaaa gctaacggca acgcaaccgc agctacggtt 674040
aatcctgcca aaatatccat tactagcttt tgaccattat aacctgcaaa ttcttttttc 674100
aaacttaata cataatcttt aaacatccta ccctttatcc tttcaaaata cttttttatt 674160
ataatgataa atattagtga tttaaagtaa aaaataaata ttttactgtt ttttattaat 674220
atttctaact tattataaaa atatcgataa aatcatcaac cataaaaaga ctactacttc 674280
tactctaaat acattaaaag aggctataac acctaaaagt ttaaaaaact ttattcctta 674340
tagcctcttt tattcagcct ctccaataat atcaattaat ttagccaatg gttcacttat 674400
atatttttct tgatgatata aaagctttgt tttattataa agcaattcat ctgtttccac 674460
cgtttttaaa gtaccatgct ttaactcctc agtaactaaa agagtaggta aaaccgcaaa 674520
accaaatcca gccttacatg cttcaatcag gacctttgaa tttacacttg tccatttagg 674580
atatgctgcc aatcctcgca aatataaaca actatcaata atatctctag ttgcactccc 674640
tttttcacga agcaaaagat catgagtaca aagttctttt aatgtaattt cattatccgc 674700
aaaataatct ggtgcacata aaacgtttaa ttgataagaa gaaaaatcta ttacaataaa 674760
gggtcctggt ggaactactc cctctaccaa agcaagatcg gcttctccac attccaaaac 674820
tgccaatgct tcttttgcac tgaccacttg cacctcaacc ttaatattag gatagctgct 674880
tgcaaattgt tttagaatct ttggtaacca aaaggttgca atagtaatac ttgaaacaac 674940
ttttagaggc gcactcattt ccaaaacatc tatttgtttt tctaagtcat gatatagtga 675000
taaaattgga ataacttttt ccaataataa tttccctgca ggagtcaata taattgcctt 675060
tgataaacga tcgaatagga caacatttgt ttgttgttct aattccctaa tcgcatgcga 675120
tactccagat tgcgtaataa ataattgttt tgctgcttta gtaaaactcc ctgtatcaac 675180
tactgtttta aatattaata aatgtctaag gttcatagct ttctcctatc atgaataaaa 675240
gtaatgtatt tcattaaatt atatcatttt actaatgtat atacaactta tataatcttg 675300
atatataaag gagaatatta atgaaagcaa ataaactaaa agaccttaca tggttgttct 675360
ttatcaatat ttttattagc agctttacat ttggaggtgg ttatgtggtt gtatcaatgg 675420
ttcgtaagta ttttgttgaa aaaagaaaaa ttttcaatga aagtgactta atcaccatgt 675480
cggcaattag ccaaacaaca cctggagcaa tcgcaatcaa tcttgcggca ttagctggtt 675540
ataaagttgc cggtaccatt ggaactatcg ttagttgcat tggagcgatt attccgccaa 675600
ttactatttt ggcagttgtt tcattatggt atcaagtttt tagtacaaat cacatcatta 675660
tggctatctt aaaaggaatg caagccggaa ttgctgctat tatcgtggat atcctaatag 675720
gaatgacaag agctattaat gaacaacatt caaaattatt aaccgcgatg attcctatta 675780
ctttcattgc cagctatatc tttaaagtta atatcgttgt aataatctta attacaatta 675840
tcgtagccac tgctcaacta tactatcgcc ggaggtactg ccaatgttaa atttatttat 675900
aattttcttt aaaattggat tattcagtat tggtggcggc tatgcaatca ttcctttgat 675960
tcaagaacag gtcgtcaata actatcattg gatcagtgcc aatacattta ctgacattat 676020
cacaatttcg caaatgacac ctggcccttt agcagttaat acctctactt ttgtgggtat 676080
tcaactagct ggaattagtg gtgctatcgt tgctacaatt ggttgtattt ttgctggagc 676140
aacaatttca attatccttt atcttctttt tactaaatat caaaaactag aaataattac 676200
aaatattcta aatactttaa aagctacatc agttggtttg atcatgtctg ctggtgcaac 676260
aattttaatt ctaacttttg ttgaaaataa ctctatcaac tttttagcaa taattatttt 676320
tgtaatttct ttattatggt tacaaaaaaa gaaacctaat ccgattgccc taatgattat 676380
cacaggaatt attggatatt tcgtatatta agacaaaacc cggttactaa atctaataat 676440
gacctttgat ttcttattta ttcagctagt tctaaaatgc ctaactaaag attatcttta 676500
tttccaatga acattttaac aaaatcaaaa aaaactgcct atatgacatt aagaagtgtc 676560
taatatgaat ggttttggtc ttgtctaatt taatatcaac aatccatttt ttacattaca 676620
tcaacaaatt agtcaatcaa tttaatatag ataattatct agcttctaaa ttactttatt 676680
aataacgctg atattcatat cctaaactct aattaattat tctgaataga taaaaataat 676740
tgtatttttt attacaaata tttatcactt ctttgataat tatcaaaata tttagtttta 676800
gtatagcttt cctaacatta ttgaaagata acaatcttac ttctaatata aatcaatact 676860
tgacttcatt gaatattgaa gataataaat gtatacataa ttcaaaatac atgaatatct 676920
cattattaaa taattttcct tactaaacca ctattcttat aattgtgtga cctagttaca 676980
gaactaattt taaattaaaa ttataataat cttgaaaatg aatcatagat taataattat 677040
ggaggaaaaa aatgaatact aatcaaaaaa ttcttatcgt aggcggagtc gctggtggcg 677100
cttcagctgc tgctcgtcta agacgtttag atgaatctgc caacattatt atgtttgaaa 677160
aagatgaata tatatcattt gctaactgtg gtttacccta ttatattggt ggtgaaatca 677220
ctgatcaaga ggctttaacc ttacaaactc ctgacagttt taaagcacgc tttaatgtcg 677280
atgttcgcaa ctttaacgaa gttactgcta ttactcctga aactaaaacc gttactgtat 677340
ataatcatca attacaaaaa gaatatcagg aaagttatga taaattactt ctttcaatgg 677400
gagcaaaacc aatcaagcca aatattcctg gaatcaattc aaataaagtt tttacactta 677460
gaaatatccc tgatacttat gcaataaaag aatacgttga tacccataaa ccaaaacatg 677520
caattgttgt aggtggggga tttattggta ttgaaatggc agaaaattta cattcaactg 677580
gaataaatgt aacgattgta gaaatggcta atcaagtcat ttctccgatt gactatgaga 677640
tggcttgtga agttcatcaa catcttataa gcaaaggaat taacttagtt ttagaaacag 677700
aacttcaagc tattaatgaa gccgataaca agctgacagt tactctaaat aatcaaactg 677760
tagatacaga tatggtaatt atggcaattg gtgtggtacc tgaaactaag attgtaaaaa 677820
atacagaaat tgcaactaat tctcgcggag caatcatcgt caacgataag atggaaacat 677880
caatcaaaga tatatatgct gtaggcgatg ctattgaaat caaaaatttt gttactaata 677940
aagcaagtta tgtaccccta gcaggcccag ctaataaaca aggacgaatt gcagctgata 678000
atatttgcgg ttttgatcgc cattatcaag gaacacaagg ttcatcaatt ttaaaagtct 678060
ttgacttaac tgttgcaagt agcggaatca atgaaaaaac tgctagggaa ttaaatctca 678120
attacgataa agtctacaca tattcagcta atcatgccgg ctattatcca ggtgcggtca 678180
atatgtcaat aaaagtcctt tttgataaat caacgggaac cattttaggg gctcagatag 678240
ttggttatga tggggttgac aagcgcatgg atgttttagc agctgctatt cgtgccaaaa 678300
tgacgggttt tgatttaact gaattagaac tttgctatgc tccaccatat ggatcagcaa 678360
aggatcctgt taacatggct ggttttgtaa ttgaaaatat tcttactgac aagatcaaac 678420
aatataattg ggatgatgtt gcatcactgc cccgtgatgg cagtgtgatt ctattagata 678480
ctcgtactga attagaatat gcaaatggtc acatcgatgg ttacattaat attccattgg 678540
attccttgcg aactcgtctt catgagctta atttaaataa acctatttat gtaacctgcc 678600
agattggact tagaggctat atagcatcac ggattttaag tcaaaatggt tttgatactt 678660
ataatctcaa tggaggatat cgcttatata atacaatttt taatcaagaa catgatgaac 678720
ccaaaatcaa gacaatgcat cctgcttgtc ccatagaaaa tccagaaaca attaaaatta 678780
atgcctgcgg tcttcagtgt ccaggtccga ttgtaaaatt atcagcatca ctagaaactg 678840
ctaaagatgg cgatattatt gaaattcaaa ctacggaccc ggcttttgct acagatctag 678900
atggctattg tcgtcgtact ggtaatgaac taatagaact tagctgtaat aaaggaatta 678960
gcagtgctaa aataaagaaa ggacagaaca gtatctcaaa cggaaataaa aataataaaa 679020
atatgattgt tttctctgga gatttagata aagcaattgc atcatttatt attgctaatg 679080
gcgcagcggc tatgggacga aaagtcacaa tgttctttac cttctgggga ctaaatatca 679140
ttcgacgacc agaaaaggtt aaaatcaaaa aaaattttat ttcaaaaatg tttgcaatga 679200
tgatgcctcg tggttcaaaa aaactatcgc tttcaaaaat gaatatgggt ggtatgggag 679260
ctaaaatgat ccgtactatt atgaaagata aaaatattga cagtttagaa gatttaatca 679320
aactagctca agataatggt gttgaactaa ttgcctgttc gatgagtatg gatgtaatgg 679380
gcattaaaca agaagaattg attgatggtg ttacattatc gggagttgct actatgttag 679440
ctaacggtga agaatctgat atgtcactat ttatataaca aaaggagctt ggaattaatt 679500
ccaagtctcc tttttatgat tgtttctttt ttcttaaaat tccaattcct aagatgctga 679560
tcaataatgt tcccgccaat atttgaatag atactgaatc accagtttta gctgctgaag 679620
tactatcatc ttttggtatc tctttttctg gcgtaggaat aactgttaca tcaccttcaa 679680
ctttatcgtt tgtatttaca tcttctttta tcactaattg atctaacgct tgatgcaatt 679740
ggtcatacat ctcatcgact tctgcctgtg cagcattttc atcatcaata attgattcta 679800
ccttctctaa caaggcttca actttagtaa gactttcaga agtatatttt tctttatcaa 679860
gtttcaatgc agtattaaaa attgatatta aattattttt atcagctttt tcaactaatg 679920
ctgcgactac ttcatttaat ttattaattg cttcatcaac ttcatgtttc gtagcattat 679980
catcattgaa aacttcttta gctttttgta aagtgactgt aagtaattca attgattgag 680040
gggtatattt agctgtatct aattgtttac ttgctgaatt gattgtttct tccaactcca 680100
ttttatcaac aatcttagta agtcctttaa cactatcttc caactgatca attgctttta 680160
agatatcttc agatgtaaca tcatcatcgt tataaacttt aacagcatta tttaatgctt 680220
cttgatatcg cgcaatacta ttaggggtgt atgatgaaat atctaaatct ttatatttct 680280
tataaatttc ctgtaactta gattttaaag ttgttccata aacttcaaat tcccatagtg 680340
aatacccata atcacttcca acttcaatcc ctaacatcct tacatatcgt cctgttacat 680400
ctttatatga taattcatca agacctccat cgccatcatt aatatctgat atatctgtcc 680460
aaacttgacc atcattagaa acttgcactt tgtatttctt tgcaccgctt ccttcccaat 680520
tcaaaataac tttagaaata ttataaatat cttgtaagtc tacatatatc cactcatcat 680580
tagatttccg attagatacc cagcgtgatt gctttccatc aactatttca tttgtacctt 680640
taccatcaaa cgctagcgaa gattcatatg ttttatttcc atctttcgaa tcaacatatt 680700
ctgagctcgc attcgaagat ttattcaaag ctaaatttac atttggattt tcaggttcta 680760
atacagcttc cccgtaaact tcaaattccc ataatgaata tccataaatt cctccaggct 680820
cgattcctaa cattcttacg tatctgcctg ttgtattttt atatgtcagt tcatcaatac 680880
cacctttacc atctgtaata tgtgatatat ctgtccaatt ctgaccatca ttagaaattt 680940
gcactttata ttctttagca ccatttcctt cccagttaag aacaacttta gaaatatcgt 681000
aatcagcttc taagtcaaca tagatccatt gtgatgttgc tgttggatca tcttttgttc 681060
ttaaagatac ccagcgtgat tgctttccat caactgtttc atttgtacct ttgccatcaa 681120
acgctaataa agattgatat gttttattac catcattagg gtcagtaaac tcgctacttg 681180
ccttagaggt tttattcaat gcaatattta cttcaggcac cactggttct tggtgtaatt 681240
ttccatacac ttcaaattcc cataatgaat atccgtattt agaagcacat tctataccta 681300
gcattttaac ataccgagca gtaacagttt cattaaatgg gatatttgca attccaggtt 681360
gtccattctc ttctagataa accttttgcc atgtttttcc atcttcagag acaagaattt 681420
gatatttttt agcaccattt ccttcccaat aaagttttac acccgttaaa tcataattcg 681480
cttctaaatc tatttgaata tattcatcat tcgaatttct atttgaaacc catcttgatt 681540
gatcatttcc accattattt tcaaaacttc catcaatagc tctatttgca gtataaacat 681600
tgttataaac tgaagaagct gttgctgttt tatttaaagc aatattctct aaattttctg 681660
cttcaacaag ttcgccataa actgaccact ggatgatttg gtatgatgag ccactagaac 681720
catttaattt taatctaaca tatcgtgctt cttgattacc taaatctgaa atgttctcat 681780
taccaccttg tccatcaatt atagttttta ctgtttgcca catttgtgca tcatcagaaa 681840
tctgaatttc ataattaggt gcataattat ttccccaatc aacctgcata cttgaaattt 681900
tataaattcc ttttaattct acatagatcc attgatcacc ggctgcactc gaaatccaag 681960
acgtattggc tttattatca attgcatgag tcggtaagtt caaatccttt attgtacttg 682020
aaaatgcatt tttattagct gcaatatcct catctttata agaaccatac acagaaattt 682080
cataaatact aataccatat tttaaagttc ttgatttatg tgacgaaact ctaacataac 682140
gcccatatac aggttcatca aaattgtatt catccaataa gctacttcca gttgccatac 682200
tatttttaac cgttatccag ttatttttgt cactagagac ctgaatatca taatcatcag 682260
aacaagcgga ttcccattga atgctcatag cattaatttc tgaatattgt cccaaatcaa 682320
ccatgatcca gttctcatct tcatttcgta atgaactcca tcttgtactt gtattaccat 682380
ctacaactaa ttctttagta tttccagggt catttgttga cgtactgctt gcttcaacag 682440
atttattaag cgctattgaa tcacttgctt taaatgtaat ttccttaatt tcaaaacaat 682500
ttccatttcc atctttcatg ataatcttaa tatatgggta gactcctttt aattcaatcg 682560
tgtctgtctt accatcacca ttacttacag atttcaataa ttcataattt ttaccatctt 682620
gagaaaccat aacatcataa gcactagcat aattatcacc ccaaagaata ttcatagatg 682680
ctaaatgttt attattgcca gtaaacatac tgatccattc attttgcgtt tcttcacttt 682740
gccaatatgt attttcatca ccatcaaaag ctttttcgac ttcgtgtcca atcattgaag 682800
aattagtatg ataacgatta tctgagcctt ctgataacgt cattgtttgt ccagcatatg 682860
gtaatgctcc tgaaacaaat gttgtttgtg tttcttgatt atcataattt aaatttacat 682920
ttacagtttg attggctgct gtatcattga ctgctacaga gatttttctt gtatcctctg 682980
attcatcaat aataatactg caaggttgat caacagtaat tatatagcca tctttatatt 683040
ccaatgaacc agcttgatag aaattaattt gagtttgttt taaaccgtca tgtcttaccg 683100
cttgaacttt ttcgttatta gcaattacag taactggtgt attaccggca tattgactaa 683160
ctgcacctgc tgtggtattt ggtacgacaa tataggcata gctatcattg cttggcttta 683220
atccatgatc taaataggct gtaaaagtag ccggagtttc attctttttt gcttcatccc 683280
ataatgacgg attattagtt tgaacactat tacttacaac tacatccgta ttttctaaga 683340
aaacatatcc aacttttcca ttatatagcc aattagtgtt ataaatttgt tctttcgttc 683400
cctcagccac actttgacca ccaacattta catcttcagc ttcgcattga tttaatgttg 683460
tatggatatt gactccctca gtagaattga tccccgaacc tagagcaaca aattcatcat 683520
caaagaagaa atatcctttc tttacttgag tccccttttt attcatatca taagcagtat 683580
ttccatattt accattggat accccaattg tatgttcagt tccatttgta aaacgacctg 683640
cattagcata atcttgaacg attcgtgctg ctgttgttgt tcctggacaa tgagcccaat 683700
catatgttgg ataaacgtta gtatattcat ctccgtcaac tgtgattgtt gaagctgctg 683760
atgatgtcca ataaattaat tgtcctccgt ctttatcata acctgaccag ctgccacgcc 683820
attcaccacc gatgatttgg ttagagtcca ttttaatatt aactccgtac ccatctcgca 683880
tgtgagaagc ataaccagaa cgccacatat aataattacc attttttcca ttaactgtat 683940
tttttccttg gatgttatca aggattgctt gatattcatc agctcgatca ggatctgatt 684000
caatcattct cttaagtgga tcgatatact ctgctgcata gttatcatag ccaacatcat 684060
aatcatatgg ccgatatcca aggtaaagct ccataatatc tcctctgatt gtccagcttg 684120
tcccatcaat catataatca gccattaaat caatgacatc ttgttcaaat gcataactag 684180
tttctcttag catataaatc caaaaactca tatctctaaa cattgacatt ccatatccat 684240
tagaatagaa ctgcctacca tgcatataga aactgttatc aacctgaact gcttcagcag 684300
tattatcatc agtttgaaca actaagcaat aacttaaata atcatctaca agttctttta 684360
aatctaattt cttaaatcct gtagaattgg tatgtttagt cccattttct gtaataattg 684420
cgtaataaac ataattttga tcaaaccata aattattttg acctgtacca tatttaactg 684480
gtgttttttc caataattta ttaagcataa tatccattgc atctttactt acaatgcttt 684540
ccataaataa agcaattcta gaaaatctta attgaactcc aatttgattc tcccaccagt 684600
tagaagaaga tggattcatt tttccccaat aaacaattgc tttatttagc ttattaatta 684660
cttcttcgtc atgataaaga gcgtttccct ctttatgata agcaactgta attgcttgta 684720
gacgatcaag agctaaataa ggtgaccatg ctgttccatt agcagcactt gatgtcgctt 684780
tgtagtcaac atccccaaaa gcaccatctt cttgaatcaa atcaagataa tcttttgctt 684840
ttgaaacata gcatgtttct acttttgacc catcatcaat cgtgtctaaa gttaaaaagt 684900
aatcttttaa acgcgttttg attgttgcaa aatcactctc acttgcataa gttacattca 684960
tggaacttaa aacaagccca aaagacataa ctaatgacag gattattctc aatgcctttt 685020
taatcatata atatcctcct tttaaataat attgaaaacg cttactacat ctattatttt 685080
tagttattat cacttgaatt tcaacgaaaa atcacttgaa aaagtttttt ataaaccttt 685140
ataatcagta gaatatggtt gaattataaa tgatgaaaac gtctttaaat ttttaaagac 685200
gttcgttcaa ctattttcac acttaataat tgtgtcatcg gaatattatc tttacgatga 685260
atccgatcaa ttagattaga taccgccacc tcgcccatca gttccttttg aacttgaact 685320
gttgtgatct gcggtactga tttaacacac aacggtgtat cgtcaaatcc aacgacacta 685380
atatccttgg ggacttttaa gcccatatct tttaacgcag taatcacagc aaatgcatta 685440
gaatcatttg cacatactaa gacctctggt aattttttag tattcaaaat ttcaattatt 685500
ttatcaattt gattagttaa aacatattct tcaattcctt gtagaaaaga atatttttga 685560
atatattcat caacctttga ataactaaca atattattct ttaacagtga ctgtttaaat 685620
ccaataaaac gatcctcaaa actaaaggaa taatcaagat ctccaaaaaa accaatccgt 685680
tgataccctt tattaataac atgcgtagtc atcatataac taccttgttt attatgcgtc 685740
aaaacacaat cacacggtgt acataatgat gtaaaatcta ctagaacaac gggtacacca 685800
atatttttaa gcagcagcag gttactatca gatattttgc ctacaactaa tattccagcc 685860
actttccttt cttcaataca ttcaggtact acgaagtgcc cttcttcaaa ataatttaaa 685920
attgaaaaat aaccaaatac ttttgcttgt tcaacgattg accgtaaaac aatcgaataa 685980
aagtgtcctg tatctgcata ataactttgc attaaaatac aaatatttga tttagaataa 686040
actgatagat attgtctttt ttgattaatg taacccattt tatcagccat ttttaaaatt 686100
tctaaacgca tttcatcgct gacaccaggt ttatcattta gtgcaattga aacggcatta 686160
attgaaattc ctaatttatt agcaatatct ttcatcgtca ctttcatctt tgtttcacct 686220
cattaaatag tatagcacat gctcctcgat tatagtactt ctccatttga tgcaattact 686280
tgttgatacc aggcaaatga tttttttcta attctacgca tatcttttaa atcatcattt 686340
tcacgattga cgtaaataaa accatatctt ttcttcattt gtgcccggct gcttaaaatg 686400
tcaaccggtc cccatgacaa gtaaccacgg caatcaacgc cttcttgaat cgctaatttc 686460
atttcctcaa gatgtttcct catataatca atacgataat catcgataat ttggccatct 686520
gcatttattt gatcattata accaaaacca ttttccacta tatatattgg catttcataa 686580
cgatcataca attgtcttaa agtaattcta agaccagttg gatcaatcgt ccagccaaat 686640
tctgacattt ccaaataagg attcttttta attacaacat cattaatatt tgttagactc 686700
tcctcaccat aatgtgaaat tgtcgacata taataactaa tagatagtga atccgtaatc 686760
cctttcttta atatttctaa atcaccatct aagatttcag gcattgttcc ttcatttttc 686820
atatttgcaa aataatatga attataatgt cctcttgcaa aaacatctaa aaaaacataa 686880
gcttcacttt gagccttcat actttcaagt gtatcaagag gatgacaagt ttctggataa 686940
ctttgaacca ctgtcgccat tcccataacc ttaccacctt tttgatgaat atattcatta 687000
ataagactat gagcaatcaa agtattatgc ataatttgat tatcaaacgt ttgagtatca 687060
actccatccg gacaaactgc cccaaaaaac atttttggcc ctttctgtaa aattccattt 687120
tgttcattaa aaataatcca attttcaact ttatcatgat aacgatcaac aatctttttg 687180
cacagttcta caaatatatc gactactttg cgactataaa atccattata cttctcatat 687240
aaaaatgctg gcatttcaaa atgatataaa gttggaattg gttgaattcc tcttttaagc 687300
agtgcatcaa taaaatgttc ataaaacaca aatccttttt cattatatac tccttcatcg 687360
ctcattaaac gtgaccaatc aagtgaaaaa cgataagcat taaatcccat ttcctgaaat 687420
aaatcaaaat cctcttcata acgatggtaa ctatcgattc cgtctttaaa atcagaatat 687480
tcaccggtaa ctgttaaatc acaaaccgct ggtactttac catccagtgt atatccacct 687540
tcactttgat gagctgtaac tgccccaccc cataaaaaat cttttcgtaa cattacttct 687600
tcctcccatt ctatttctag cagtatagct attttttata taacaaatta ctattactga 687660
tatagattta ttatctttaa tgtcagcttg aatttcaact cataatcact tgaaaaaaaa 687720
ttaattaact tgaataaaaa agaataatca taatgattat tccataatta atcaatagtt 687780
agtttatcta atttatgttt atcaactatt gttatttttc ctcgtgatat ttttacaata 687840
ccctcttgac taaaatattt taacatccta gttacaactt cacgagccgt cgccatatat 687900
ttagcgattt gttcatgagt aatttttaac tctaaagaat tattcttttc agcttcttcc 687960
ttaagaaaaa tagctaagcg tttatcaaca gacataaata aaatttgctg catcgcccac 688020
ataacatcag aaaaacgatt ggttgccatt ttatacccaa atgtttcaac ataaatattt 688080
tgcttcgcca attgttgaaa taaagttgcc gtgattgtaa tgatttcact attttcttca 688140
atatcaataa aaacatcaaa tgtaatcgtt tctaaaacac atgatgccga aagaatacat 688200
acatcacctg caaataaacg atatagtgta atatcacgtc catctggtga taacatatat 688260
gtccgcaatt gaccctttct cactaaaacc acacctaaac aatcatcact accacgatgc 688320
attgttatgc ctttagcata agtttgaaga gtggcatttt gttttaataa ctctttttcg 688380
ttttcattta aatgatccca aaaagttaag aattttgtta attcttgctc catcattttc 688440
accctttcaa attaattcaa attttttaat gctttaaaaa tgccatcatc attaatcgtg 688500
tcagtaacaa aatcactagc tgccttaact aaatcattag cattccccat agcaacacca 688560
actccaacat gttttaacat atcaatatca ttattcccat cgccaaatgc cattacttca 688620
cctaaattaa tttgatagtg ctttatcatt tgatcaattc ccttattttc tccgccatca 688680
atagggatga tatccgcaaa gagcgatgtc cagcgtgctg atttacaatt aggcatatat 688740
gataatcgtt cactatcttt agtctcgtct atatatgcca ttaattgaat tatcttactt 688800
tcaattattt cattaacagc tttaatggga tagccctctt tattcagtga tctagcagct 688860
tcatcaagac aataattttg gatattacta taattaccat ttatttctac aaataatacg 688920
ggaatctgat ttttgttaat atatggtaat aaatttctaa tatcttctct ttcaatatat 688980
ttttcatgaa taaccacttc atgattaaaa caatactgtc cattacttgt gagaaaacca 689040
tcaaactcga aacaatcttg aatcacttta agattattag gtggccgccc agtagcaacg 689100
aataatctaa ttccattctt ccgtaatttt tttaatgctt caaaagtact agatggcatt 689160
aagtgtgtat catgatccaa tagtgttcca tcaatatcaa aaaattgctt ttatcatcta 689220
cttatcctca tattatttta tcttttagtt cttaacataa taaaataatc gtctttttat 689280
tataatgttt tccaatacag tatagcatat gtaatccttc aattcataaa aagagaaagt 689340
aatagttact ttatcttaac tactatttga ctaaatcaac aatcaactca gtacatttat 689400
cgattccaat ttcaccacta tttaaacata aatgataatt ttgcgctaac ccccaaactt 689460
gatcagtata atatttataa tttgctcgtc tttttttgtc tttatcagct aaacgtttct 689520
caggcttctc atctgtttcc ccatataatc tgacgatccg ttccactttt ttatcaagat 689580
cactacaaat aaagacatta aaacaatcat ctcgatctct taaaatataa tctgcacatc 689640
tcccaacgat tacacatggt ccttcttgca ctaattctaa aataatcttt ctttgcatca 689700
tccaaatata atcattcatt gacatcccat caatataatg acctaaaaaa gcataagcaa 689760
aaggattact agatggtgca tattcaccat gttcttcaat ataattcaca tttaatccac 689820
tctctcgagc tactttttca attaattcct tatcataaaa aggtatgttt aatcgttttg 689880
ctacctcttt accaattgtt ctaccgccac taccaaattc acggctaatt gtaataatgt 689940
tcttgcgcat gatctgcacc tcctcctaat cttagtcatt atctatactt taattttact 690000
actttacaag cgaaaagtaa tgagaaatca ctaattttat tgtccaaaag atatttttta 690060
taccattcat acaataaact ataccattca tacaataatt aaaatatact aaaagtaagc 690120
ccctataata aaggtgtaaa agataactgc aagtaataaa ggagatttct aaatgaaaaa 690180
aattggatta atggttgttg ataatagtgt gatcaaacaa ttaaaggaac taatcattaa 690240
aaatattgac agtgaatatc gtatcattga gattcatgat aaggaaatgt tatttacaaa 690300
aaaaatggat ttctgtatta ttgaagattc ttttgataat caaggaatca attatgctaa 690360
aacattaatt gaaaataata atgatatgct tgtactaatt atctcaaaag acggttcaac 690420
tattttcgat gcagtaggta ttaatatttc cagctatctg cgctatcaag atattaaagc 690480
gaaatttgtt ccagcaattc aagatatcat cgattatctt gataaacgaa aattactact 690540
atttaaaagt gatcagggca tcgtcaatac ccaaacaaat gatattgttt attttgaata 690600
tttaaatcgc atgacatatc taaacacatt agacaaaaca tatcgcattt ttattcaaaa 690660
ctttgaatat ctacaaaaaa tgcttccaaa aacctttttt aaaatctcac gttcagcaat 690720
tatcaatatc tttagattaa ttactttaaa cagtgaaaat gtaattatga aaaactacga 690780
aaataaagat attgctattt caagaagaag atatcaagat ttacttgtag tgttaaaaaa 690840
acatgctatt tcttttacag aaaggaaact aaaaaaatga aaacactatc tacaaaagca 690900
tctaaacaaa aaatcttatc tttattatta ttagctggtt tatggagtat catgctgatc 690960
attgtcttac tcgcagctaa aagtacttgg gccaaaaatt taaatagtcc ttattgggct 691020
ccagccatca ttacaattgg aataattttc tttatcactt acttcatctt cactgtaaga 691080
gcgttatttt accgccagca cggatatgat aatcaatata tatattatta taaatcaaca 691140
agttatttta atatccttaa attaattatt aatacgcttt ttaataaaga aatgtatcaa 691200
gataaaattg cctttaagga tattaaaaaa tgtgaaattg gatggtataa tcaaacattt 691260
agaatacact catttggaag tgaagtcgct catccaattt attttaagat taatgaacag 691320
atggttatta aaacagattt aacttcaaat aatgagcata ttattgagtt agctaatctt 691380
cttaaaagtc atgtaaaaaa ctttaaagat ccctaccatt tagttttagc aatgaacgat 691440
cgcagtatta ctgtatacga atatattgaa cgcatcattc ataacaaaat aatcaaacca 691500
aatctatata aatagacgtg cgaatatttc acacgtctat tctttattat tcaaaattta 691560
aataatatat cataaaacta tcctgctcac agttttccca agactactta tacaaaattg 691620
ataaatttta taattaaata gcaccttttc aaacacccta ttactatatt caaattttga 691680
tttgaacttt tcataacaat tctttccaat caattttcaa acttatctaa acatatatta 691740
ttactatttc ttataaattt ccagtattct acaaaagctt ttgtttcaca cgtaattact 691800
ctattttctc ctcaatataa gcccacaaac aatcctcatt atcattttct atcgtatagt 691860
tcaacaacca tatccaataa tttaatcttt tttatacgtt ccttcttagt ttcccatttt 691920
tctaacaatg tgggggcaaa taatctttta atgtttcatg atcttgattt gaccatgaca 691980
tttaaatcgc ataataacgg ttttctactt ttttttattc gttcctcatt ccaaaaatta 692040
tcactgctat ctaaaactaa caattgtttt ttataagtcg atatattttt agagctttca 692100
tttgatgttg aagtgccaca ctaataaatg taacaatgaa aatatcagca aaaatcagta 692160
cactaatcat gcataataat tcttaatcat catcccctct taaatgttaa attattcaaa 692220
tggataaatc attccccatt gagtccgaat ttgacttagc agtgaactta catcccgagt 692280
taactgtaat tcatattcac caagattatt tataatataa tcttgcatat caataacttc 692340
gtattgtagt ccctgtttat catcaccaca ttcaatgact tcctgatgac catctttagt 692400
ataagttatc gttgcttgat tactccgcgg ataattatta atttctatat accccaattc 692460
tcctgatatg accccacgct tcggttgttt tgcacgcatt gttagagcca ttacaaccat 692520
ttgaccatct tgatttttca taatgattcc tgattgttca tcaaccccag tttcaaaata 692580
atcagcagtt gtaattacaa cattaggttt tgatgataaa aagtaccggg caaaacttgt 692640
tgcataaaca ccaatatcta ataatgcccc accagctaat tcttttgaaa agaaacgatt 692700
attaacatca tattctttac agctgccaaa attgacttga atcattttta catttccaat 692760
tactcctgca gcaaccattt cctttaattt tttgtatagc ggcatatgga aaattgtcat 692820
agcctcttgt acaacaacat tatttttctt agctaaagca actatttctt ccaattgacg 692880
atcatttaca gtaattgctt tttcacataa aacatgcttt ttcactgcta cagcctgttt 692940
catgatttca taatgactat tatggggtgt tgcaatataa acaacatcaa catcaggatc 693000
atttaataat tcctcaacac ttccataagc atttttaatt ttatatttca ttgcaaaatc 693060
aattgcttta ttcatatcac gatgtccaac cgcatatatc tccccattta catccaacaa 693120
agcctgagcc atttcattag caattacacc actgccaata attccccaat ttaatttttt 693180
cattattatt tcctccgtct aatcttcata gatatattat acatagatta caaatagaaa 693240
aactagcaag aaaataattt tctcaccagt ttcataaaag cctatctttc tgacatttta 693300
aaatctctta aagcttaata aaaaactcaa aaatttaaat aaagtattca ttttccctag 693360
gtgttgccag tttcttgcta aaactttctg caaatgtttg atattcttga ttgttattca 693420
tactcttagc atggactggg caaatacgaa tacatctaaa acaagcaata caatcattat 693480
taattgtctt acaatcttct atatcaatag catttgtagg acacatattg acgcaaaccc 693540
cacagccgct gcactgttca ttagtttctg ggcgaaattt tcccccagtt cctccttctt 693600
tatatgggta tttccctggt actgaaacaa atgaaaaatt atcatcttta atttttagcc 693660
gcaccaaact accaaacaat tcatcacgat ataagtcatc acgattagga cgacccactt 693720
gaatttgacc ataagtatgt tcacccacta aagctgcacc agcaatagga ataaatcctt 693780
gctccttaac agtattaaat aattctaata atgcatcatc ataatgacgg tttccatatg 693840
taacagtaat tacacatgat gtatgatcac cccgaaatga ttttaaccgt tccaaagcct 693900
cgtgaagaat tcttccaccg taaaccggaa aaccaaaaac tacaatatca tgacgactaa 693960
atgtcatctc tggaatcgtt tcttctagtg ttaaatcaat ttcacttaac tctccctcaa 694020
gtccacgagc aatactaaca gctgacttct tggaagtgta agttggtgaa aaataaattg 694080
catatgtccg atcaatcttc ataatatatc ctcccacctt tatttattct tttattatat 694140
cattaaaata tgtactatct attaattaaa aatagattat cacaataaat tgtattatga 694200
ttaaactaga ggtgatgaaa tgagtaccta ttttataaat cgtataacta ttgatcatga 694260
tttaatcgag cgaaacagtt atctaaatac aattgctaca attaaatact ttgatttttg 694320
ataatccgat tacctttttt gttggagaaa acggcacagg aaaatccact ttattagaag 694380
caatcgctat taaatatggc tttaaccctg aggggggaac tttgaacttt aattttcaca 694440
ctaacaatac tcattcatct ttgcatcatg caataatcct tgatcgtggt tatcgtcgtc 694500
ctgatgaagg cttcttttta agggcagaaa gtttttataa tgtcgcaaca caattagaat 694560
gatatgaaaa aaatgttttt aatccctatc gctattatgg tggtaaatca ttacaccagc 694620
aatcacatag tgaaagtttt ttaacattga ttcaaaatcg ttttaatcag aatagtctat 694680
atattcttga cgaacctgaa gcctcattat caccccagcg ccagctaact ttattaatta 694740
ctatttatga attagcaaag cagggctcac agtttattat tgctagtcat tcaccgatcc 694800
tattaggaat ccctgaggca aaaatactta attttgactc aaaagagata acacctattg 694860
attatcaaga tactgagagt tatcaaataa cagaactctt tattaataat cgtgccggtc 694920
tattaaataa attattaaat aaataagatc atctaccctt tcaatatgat tttattttta 694980
taaaaaaact agctgcataa gcagctagtt aagccatttc tgttaaatca tcttttattt 695040
catcaaaagc aacggcaatg tttaaaccat gatcaccaat tctttcaaaa tcaattaatg 695100
tttctgtata taatgcacta tgttccggcg tacatttttt atctcgcaaa cgtcttaact 695160
gattaagtga aaattcatgt gttgtaatat caatactatc ttcaataaca tcaacttttt 695220
caacaatgtt atgaagttca tcgcgattta agacatttaa ttcctctaag atatttcttg 695280
tcaggtcatt cataatttta atttctctca tcgcttcatc tgaaaaatgt tcatcttcac 695340
tatataattt ctcagcacgt tcagcaatat taaccgcatg atctccaact cgttctaaat 695400
ctccagccgt ttttaagaat aagccaattg atttagaatc atcgattgga aattcattag 695460
aaatagcatt ggttgtaaac tgaataattt ctttgtttaa ataatcaata tattgttcat 695520
cttttaataa tttttcatgt gtcttttcat catacttaat aattaaatca aaagctcttt 695580
gaacattttt ttgaactata tttaacatat tttgtgtttc attaaataat tgtgtgttag 695640
cgattgcact agttccaatg tgataatcat tggtaaagat actattatcc aagaacttaa 695700
cagataattt atcttcaaaa ccttcttttt caggtaaaac caaatatgac aatttaacta 695760
actgcgcccc gaatggcagc aataataatg ttgtaacaac attgaatacc gtatgtacat 695820
tagcaatttg tgccggaata tttgttggcg tcaatgactg cataaatgat gcaaacggtg 695880
ttaacatact aataaaaaca aagacgatcg ttccaataat attaaatgaa agatgaatga 695940
tcgttgtacg ttttgcatta cgccctgttc caatactagc taaaacggca gtaatacatg 696000
taccaatatt ttgaccaaat aatacatata ttgctgatgg taaagtaatt acgccactca 696060
tcgctaaagc ttgcaaaatc ccaaccgaag ctgaagaact ttgaattatc gctgtgaatc 696120
cagcaccaac taaaataccg attaatggat tttcaaacgt agtgacaaga ttaacaaatt 696180
ccggtgaact tctaagcggt accatcgcac tagacatcat ttccattccc atgaagagaa 696240
ttccgagtcc cgcaataata ccaccaattg catcaagttt tttacttttg aaaaaagcaa 696300
ttaaagcaac accgacaaat gcaataactg gtgctaaagc tgtaatatca attgcgatca 696360
attgacctgt aattgtagta ccgatattag cacccataat tacccaaacc gcattttcca 696420
atttcatcaa cccagcatta acaaacccaa cagtcatgac tgtagttgca gatgatgatt 696480
ggattactgc agtaataact gctcctactc caacgcctag aaagcgattc gtcgtaagtt 696540
tttctaaaat tgttttcatt ttgtttccag ctgctaattc gagaccattt gacatcatcg 696600
tcatcccgta taaaaatagc gctaaaccac caaacatagc aaagaaatct gtaagttcca 696660
tcttattccc cctgttacac ggttacttta acataaaatt tacatactgc aaagattgtt 696720
aacaaattct taacttttct ttacatattt ttacgcattt tattaagttt attcaatttt 696780
cttgacaatc ctccaattta agatactatt actatagaca gttcatttgt accatcctgt 696840
ctataaacaa aactagggct atgcttttta tgttgttttt aagcaggctt tttagtgagc 696900
ctgctttttt atttgatggt atagaaggag gaaagatgta ttttttaaaa acggaacaaa 696960
gttttgatag tgcacatttt ttagctggtt atcatggtaa atgtgctaat attcatggtc 697020
atcgctggaa agtcattgca actatcaaaa gtgaaaaact gctagaagat ccccaaaata 697080
aaggaatggt aactgatttt ggagatttaa aaaaagattt aaaaattatc gcagatagtt 697140
ttgatcatgc tttaattatt gaaacaggca gtttatcaga aaaactatac caagcactga 697200
tcgatgaaaa tttcaaaata atcaacttac catttcgtcc aactgctgaa aatttagcta 697260
agtatattta cgaggcttta agtaaaaatt atttagttga ttgtcttgat gtatatgaaa 697320
ccccaaataa ctgtgcaagt tatcgaggta aattatgaat aattataagg ttgttgaaaa 697380
atttattagt attaacggtg aaggaagtcg tgcaggtcaa ttagccgcct ttattcgttt 697440
tcattattgc aatttaaatt gtagttattg tgatactagg tatgctaatg attcaaatag 697500
caattatgaa cttttaagtg ctcaaaatat cctagattat ttaaaagcaa ataaagtcgt 697560
taatgtcact ttaactggtg gtgaaccatt acttcaacaa aatattgatt atttaattga 697620
tttactgctt aaaaatggtt ttagtgttga aattgagact aatggtagta ttgatattaa 697680
accctttatt aaagaaactc gaccaatctt tactttagat tataaagtac ctagcagtac 697740
aatggaaaat gaaatgtgct taaataacta tcaatatttg actaaaaatg atgttgttaa 697800
atttgtagtt agcaatctca gtgatttaaa taaagcaaaa gaaataattg atacttatga 697860
ccttgtcaat cgtaccaaag tttattttag cccagtcttt ggtaagattg aaccacggat 697920
gatcgtcgat tatatggtca aacatcatct aaatggtatt aatatgcaac tacaaatgca 697980
caaattcatt tgggatgtta atcaaagagg tgtctaaaat gattgatact aaaaaaatag 698040
aggaacacat ctacggtatt cttaaagcct taggtgatga tccagaacgc gaaggattaa 698100
aagatacgcc taaacgagtg gcgaagatgt atggcgaagt ttttgctgga atgaactata 698160
gtaatctaga aattgcaacg atgtttgata aaacatttat tgacgattta gacttcgata 698220
atcaagaggt tgttgtaatc aaggatattg atatctttag ttattgcgag catcacctcg 698280
ctttaatgta tgacatgaaa gttacggttg cttatattcc ttgtggtaaa gtaattggtc 698340
ttagtaaaat tgcacggatt gctgatatgg cagcgagacg tctacaactt caagaacgaa 698400
tcggaacaga tattgctgaa attattagtc tagtaacaaa ctctaaagat atcgctgtaa 698460
tcattgaagg taaacatagc tgtatgtcat ctcgtggaat caaaaaagtt aatagcacta 698520
ctgtcacaag tactctaacc ggtcgtttta aaactgatag taagctgcaa atttatttac 698580
attaaggagt agtaagatga aagtattagt attatttagt ggtggagttg attccaccac 698640
tgcattagca ctggcaatcc aagaacacgg aaaggacaat gtagttgctc tttcaattag 698700
ttatggtcaa aaacatacca aagagataga agtcgcaaat aaaattgccc aattttatca 698760
agttgaacac ttgtatttag atttagcaaa aatcttcact tatagtaatt gctcattact 698820
acaacattca gataatgaga ttccccacga atcgtacaat gagcaattaa ataaaacaga 698880
tggcaatcct gtttctactt atgtgccttt tagaaatggt ttatttttat ctagcgctgc 698940
tagcattgcc ctttctaaag gctgtaatat tatttattat ggtgctcata gtgatgatgc 699000
agctggaagc gcatatcctg attgtagtaa agtttttaat aatgcgatga accaagctat 699060
ttatgaaggc agtggccatc aattggaaat caaagcccct tttgttgaaa tgaccaaagc 699120
agatattgtt aaaatcggtc tttcattagg cgtaccttat caattaactt ggtcatgtta 699180
cgaaggaaat gatacccctt gcggcacatg tggtacttgt attgaccgcc aaaatgcttt 699240
tttgaaaaat ggaatcaaag atccattatt aggagaataa aaatgacaaa aaatttaacc 699300
ttattaggta atcaaaacac tgtttataaa gatgattatg cccctgaagt attagaaact 699360
tttgataaca aacatcctga aaatgattat tttgtaaaat ttaattgccc tgaatttact 699420
agtctatgcc ccattacagg acaacctgat tttgctacta tctatattag ttatgttcct 699480
aatcaaaaga tggtagagag taaatcatta aaactgtatt tattcagttt taggaatcat 699540
ggtgattttc acgaggattg tatgaatatc attatgaaag acctgattaa attaatggat 699600
cctaaataca ttgaagtttg gggaaaattt acaccacgtg gaggtatttc aattgatcca 699660
tattgtaatt atggaaaacc agaaacaaag tgggaaacca ttgctttcaa ccgtttagct 699720
aatcatgatt tatatcctga gaaaattgat aatcgttaaa tataattatt agagaccttt 699780
ttcaaggtct ctaatttgtt ttcaacttta catcaaagag ttagctcaaa aaaataatat 699840
attttaaaac cgttgacatc atattaatca tcatttatac ttacattaaa tacttttata 699900
aaactatttt atataagatg tctggaggaa gaaaaatgaa aagtgcagta ttttacggaa 699960
aacatgatat taaggttgaa gaagtagaaa tgccacaatt aggtaatcaa gatgtattaa 700020
tcaaagttat ggcctgtgga atttgtggta ctgatgtcca tatttatgag ggtgataaag 700080
gagcagcaaa tactactcct cctactattt taggacatga atttgctgga atcgtcgaag 700140
ctgtgggaca tgaagtaaaa catgtaaaag ttggtgatcg tgtctgtgtg gatcctaatc 700200
aactatgcgg aacttgttac tattgtcgta gtggtattgg tcatttttgt gaagatatga 700260
ttggcatcgg aacaacacgg gatggtggtt ttgcccaata ttgtgcagtc aacgagtctc 700320
aagtatataa actagccgat acaacatcat ttgaagaagg ggcaatgacc gagccagttg 700380
cctgctgctt acatggtctt gacatgtgca acattactcc ggctagtaca gttcttgtta 700440
ttggtggtgg catgattggt ttgttaatgg ttcaattagc aaaattagct ggtgctcatg 700500
aaattatctt gtcagagcca gttgctgtta aacgtgaaat ggggcttaag atgggtgcta 700560
ctttaaccgt cgatccaatc aatgacaata ttccagctct tttagctgat aaaggaattc 700620
atcgtatcaa cactgttatc gagtgtgctg gtctacctgc aacaattaaa caagcaatca 700680
gcttagctgg taataaatct gtagtaatga tgtttgggct aactaaacct gatgatgaag 700740
tggctatcaa accatttgaa attttccaaa aggaaattga aattaaagct tctttcatca 700800
acccatatac tcaacaacga gctttagact taatcaatag taaaaaaatc gatgttagtt 700860
caatggtttg tgatatttgc agtttagata aattagccga tattctttca aaaccagaat 700920
taagaaataa aggtaaatat attattaacc catggcaata agaatgtaca attttatgta 700980
cattcttttt ttgccatata tgaaaaaaaa tggacattcg ccattttgtc ggttaagatt 701040
taactgtaag gagaacgaat atgaaagata ttgaaaatgt atgtttagaa gttgatgagt 701100
tagatttcga caactatagt ccaattagtc cagatattgt tttaacatca tcatttaaat 701160
ttaaaaattt tgaccactat gtgaaagtga atgctaaaga agaatttgct tatacataca 701220
cacgggacgg gaatccaaca cttaatttac tagaaacaaa attagcacgt ttagaaaaag 701280
gtgaagcagc tcaaatgttc gcctcaggaa tgggcgctat ttcagcatca attttaacct 701340
tagcaaaagc tggtgatcac attatcattg ttaatacagt ctatggctca tcagttaaat 701400
taatcaaaca attatcaaaa tttggaatcg aaagtactaa aattgatgtc agtgatactt 701460
tagaaatctt tgattatgtc aaaaacaata ccagtatcat ctattttgaa agtccatcat 701520
cacaaaaatt tgagatgtta gatttagaac taatcagtaa atttagcaaa gataaaggta 701580
tcttcacgat aatcgataat acttggtcaa caccattatt acaaaatcca ttagttcatg 701640
gaattgatgt tgttattcac tcatgttcca aatatattgg tggacatagt gatatagtcg 701700
gtggagtcgt aatttccagc aaaaaaatta ttgatgaaat agttgaattt ggacaagttt 701760
tactaggcgc aacgatgtca ccaatgaatg catggttagc acttcgtggt ctaagaacat 701820
taccggttcg tctaaaatca caacaagaaa cacttcaaca agtaattaat tttctacaag 701880
aggatcctcg aatcgaacga atttatcatc ctctttgtaa cggagagcaa caaaacgaac 701940
ttgctcataa atatcttaaa ggatatggta gtttattagg ggttgtctta aaagatgcaa 702000
atccagaaat cattaaacgt tttatcgatt cattagaaca ttttacttta gcctatagtt 702060
ggggtggttt tgaaagttta gtaatgtcag tttataaagg aaacaatatt aatgagataa 702120
aagaacgtgg tctatcttta ggacaacttc gcatgtatat cggacttgaa gatagtgaat 702180
tattgattag tgatttaaaa aatgccttgg atcaagcata tcagtaataa aaataagggt 702240
tgagcaatat tactcaaccc tttctttaaa taaattgacc ttgaggcaaa tccagataaa 702300
ttctcgcatt taaaattttt tgtccattaa cttgagcttt atttgaaaaa agacgtatta 702360
gtacaataac tgcaagttta ttactagata gagcattatt atcacgatta gcaattaaaa 702420
caacattatt tgccacctgc catttgccat tacaagcata aaaatcttca agctctcgtt 702480
tacacgtaaa aattccaaaa tctaaattat cctcaatcca tttagtcgct gtttgaacta 702540
tttttgaact taatccctgc ctacgataat ttggcaaggt agcaatacaa ctcaatccac 702600
caatttgata tttttcatta tctatcgttg tttccatccg aagaactgct ccgtaactaa 702660
caacctgatt atctttcatg atatagaatg actgcactgt aagttcttcg ttatgggcat 702720
cattacaatc atcactaggc caaacaacat gtaaaagatg tacaatttct ctttttattt 702780
ctttggacat ttgataatag tccaaagaat aaacagtaat ttcttccatt atccaagtaa 702840
ttcttgcaat gcattaatgt ccgcaactaa ataatcacta ttacaagcca tcaattcttc 702900
ttttgtccca taaccataca acactccgat acaaggtaaa tcattttcat gggctccaat 702960
cacatcatgc tttcgatccc caaccataat cgcttcatct ttatcaatca tatttgctgt 703020
taaaacataa tcaattactt cagccttttt ttctcgtcca ttaaactcac taccgccaac 703080
aaaatcaaaa tacttagcta aaccaaaatg ttctataatt tctttagcaa atttttctgg 703140
ctttgaagta gcaactaaca atacttttcc ctgatctttc aaagtttgca aacacacttc 703200
aattcccgga tatactttat tatcaaaaat tcccttggtt gaaaaatatt cgcgatattt 703260
aactactgcc tcttcggctt ttaaagcatc aaaaccataa aattcttgaa aagaatctct 703320
taaaggtggt ccaataaaag gtaacaaatc atttaagtca ttaacttcga ttccataata 703380
atttaaagca taacgtactg atttagtaat ccccttcatc ggatcagtta aggttccatc 703440
taaatcaaac aaaatatatt ttttattcat ataagtcctc cactacacta acttatattt 703500
tatccattat tccctacatt agcaactata tatgcccttt tatctgtagt aattaataaa 703560
tgtttttgat caatgatcat tacttctttt aattgctcat ctaattcttt ttgtggatcc 703620
aaatcaacta actgattact ttcaatatca taaagataaa gtttttcatt attaaataaa 703680
acaagataat ctatgctaca ataagttccc atataattag taccataaaa atgataatca 703740
attcttgaaa cagcgcctgt aataatattt gttaacttaa tcgtttcatc actatattca 703800
atattgacaa tcgttccttc caaaggatat ttatctaacg ttctaacttc atttgttaaa 703860
atattaatta aataagaatg tccattttca tcataagtaa caacagtctg ttcatcaata 703920
aaagtaatac aattactatg catatatgga tcgatatttt taatgagatt ggtttctcca 703980
gtttcaatat tataattttc ccacccctga tcactcttat taattaaaat attagtttgt 704040
tgtggtgaag taattggatt tactgaaata ttatcattag taataaaact tatttgctta 704100
ctttctaaat taatcttagc aatatttaaa gcacgctgct ctccatcatt aatatcgaca 704160
caaacataaa tatcattatt aataatttta ggcaaaacac tatatataca tccattaaaa 704220
tcaaatgcaa ctattcgctc ttgataatcc gcatatttaa aactgaattc atgaccagct 704280
atactcccgt aatactcatt aataggacat tctcttattt gttcattttc taacgtaaaa 704340
actttaagaa aattataatc ctcatcaatg attccaaaaa attcattttc agcacgccaa 704400
tgcccataat ctagttttaa tgtgggagta tttttgttga ttgaagaaaa ttcaagagct 704460
gaactaattt tcaaattact gctaaatcgc tgactcaacc aagtacgaaa tgaatcagaa 704520
aatgcataag taattcccaa tgaagaaatt cctattgtca taacaattaa aacaattgca 704580
aatatatact taattctaat caccttcgct ctttttgtcg gttcaaaatt agttgcagtc 704640
acttcatcga tccagtttct aggagttttt attaagtcaa attcattaaa tttattcata 704700
aaaatcatct cccaactttt tctttaacaa ttttcttccc ctaattaatc gtgattttat 704760
cgtattgtga ttttctttta aaatagatgc aatttcatta gttgaatatc cttcataata 704820
atacaagtat aaaacattac gatatttact tggcatattc attacaattg gtagaataat 704880
taaacgctga tcttcttgac ctaaaatcaa cttatcaata tcaatttccc ttttccaaaa 704940
ttgtttttga taatctttac attcattgat agttacccta atcaaccaag cttttaaatg 705000
ttcctcactt tcaaatttct tgttgtaaca gtataatttc ataaatacat tttgatagca 705060
atccttagca tcatcataat ttttaacatt cataacagca attctagtaa ccatgtcact 705120
atactgatat acaacttctt catatctttc tttttccata acgatccctt ccactatgaa 705180
tacgattaaa aatgttcaac gggtgcatta ataattattt tttatacttt cattataatc 705240
gattgtttta cttttttatc gatttagtaa aataaaacag cccaaaaggc tgttattgaa 705300
gaaaatcgtc tttacgctga actaatcttc taacaaattc tgttttagga tgttctaaaa 705360
tttctcttgg tgatgctaat tgtacgactt taccttgatc cattaccata acccgactac 705420
ctaatttcaa agcttcatta atatcatgtg ttacaaaaat aatcgtgata ttttcttgat 705480
gatgaattct taaaatctca tcttgtaaag tagaccgtgt gatttcatca acagcaccaa 705540
atggttcatc cattaaaaga atatctgggg aagcagctag tgctctagca atccctactc 705600
gttgctgctg cccaccactt aattcactag gatatcgatg aattaactct tcatctaacc 705660
ctactatttt catccatttt gatagtgctt cataagttct ttttttatca tttttattta 705720
ataagttagg cacataagca atattttgag ctactgtcat gtgcggaaat aagacacttc 705780
cttgaattgc ataaccaatt cctcttctta attcaattaa atcaactgcc tgtgtacatt 705840
gatcatgtac aagaacttgt ccttcatcag gaattattaa accattgatc atttttagaa 705900
tagtggtttt tccacaccct gaactaccaa ctacagttaa aaactcacca ggtgtaattt 705960
ttagattaaa atcatcaata attacttttt caccataaac cttttttaca tgtttaaatt 706020
caatagctgt atccatatgt tcctcctatt tcactaaatt aatgctaact aaaaattcgt 706080
gagccacatc ttcagcatct tgtccttttg tttcaaccaa atagttcaat tgtgccattt 706140
ttgtttcatt gagaatacca gtaagtttat caaaaacatt atttaattct ggatattgtt 706200
caagaatttc attgcgcaca actaaggccc ccatcgaagt tgaaaagaat tgttgatcat 706260
cttcaaggac aacaacattt gctgttgata gttgaccatc ggttgtaaag acatccatga 706320
catcaacctt accttcattt attgcctgat attttaaacc aatgtctaaa tccatagtat 706380
tcttaaaagt aaaattatat ttttggcata gtgcatcata accctcagga atttcataaa 706440
aatcatattc agctccaaaa actaattgat tagatattcc tgctaaatct gaataagttt 706500
ttaaattata ctgctcagca atctcttttc ttactgctaa accatatgca tcactaaacc 706560
ctaacagccc tgtccaggta aattgatatt tttcttgata ttctttaact agctgttcat 706620
acattgtttc attataaaaa ccttcatgtt ttaaaactgt attccaaccc gtactcgtat 706680
actcaggata taaatcaaac tcaccgctaa ccattcctgg ttgaatattt gaagttcctc 706740
ctcctactcc ctgagtaatc ttaacttcaa tatccgtatc ttgttcaatc atttctttca 706800
acattgctcc aataatatat tgctccgtca taggcttagt agcaatattt aaagttactg 706860
tttgattaag attgcctgaa atcattgata tgatcaagac tgcacaagtt gtcacaatta 706920
ctactaagcc atactttctt ttagatttta aagtagcttt tcgaatggta aataactttt 706980
caataaagcc taatactata tctgtaatta atgcaagtat tgcaatcaat aaactacctg 707040
tcaaagtcat tgccgtgtta ttggtagtaa ttcctcgata tatcgctacc cctaaaccac 707100
cggcaccaat aaaagaagca atccctgcta atgctattgt catagttacc atatttctaa 707160
aaccagacat aattactgga agtgccaacg gtaacttgat tttgtataaa atttgccaac 707220
gtgttgatcc catccccgtt gcagcttcaa taatattatc atcaatatta ataattccag 707280
tatatgtatt tctcaccatt ggtaataatg cataaacact taatgcaatg attgcggtac 707340
tattaccaat tccagaaaaa ggaattaaaa aacctaatag tgaaatagag ggaatcgtat 707400
acataaaatt aataattcct aaaattgttt tagaactttt tttatattca ctgattatta 707460
ctcctaaaat caagcctata acagtcgcaa taataattgc aattagcgat atctgcatat 707520
gttcaattaa taattttaaa aagaaatccc ctttttcttg taataaagat agcatatctc 707580
ttaacataat ctaacctgct ttctcaattg cccgcaccgg acagttttca taacataaac 707640
cacaatgtaa acaatgatct tgcattattt tatacttgct tccactttta atacattgtt 707700
gtgggcattc acgcttacag cgatcacaag caatacacct attactaatc agatatcctt 707760
tattaaaaat tcgattatca caaagatcat attgtgaacg ttcaattggt acttttgata 707820
aatcaaatat ttcaatttca ccatcaaaaa tacaaaatac ttctaaaata ttacgactat 707880
cacctggata aacctcattc atactcggat tatcaataaa tattttttct aaccattctt 707940
tttgattact gactttttta acttttcctt ttaaacgaat cgatgcataa tcttttgtta 708000
gcgcaactaa tgaaacgaaa tttttatcaa gtaattcttg ataaaagttt ttcccccgag 708060
cagtcaaaaa atacaaatta ttattttcca cagccattac atcgatgatt ctaatttgtg 708120
gatagccgtc actgtctaca gttgccattg ctacatcttt tatttttcta agttcattta 708180
aataatcatt aactttcatc actcttacct ccgctcgtct ttaatataca ctagttgatt 708240
tttatatgaa agaaggcact tttttgtaac ctagttactt taacgaaact aaaaaactat 708300
agctagtcgt gtacaacttc atagctatag ctctaataat aatcaaactt atactctata 708360
atattgtatt aggcacacca taagtatact gttctaatat caaaataaca aatcatatgc 708420
ctaaaataaa ctactttgca aaaaacctga agtaatcgtc aaagactgtg gtactgtcct 708480
taaaagtgct tcaatatgac gattttctaa ccagtcatga tttaaatgct cctctaaaat 708540
caatggcatt cgatcatgaa tctcacacat acttttattt gcttttgttg taacaatagt 708600
cacttctgtt tgcccgttaa catttcgata aattcctgtc attaacaata acgatcgttt 708660
ttcgttttca aaagtgaact tatgtttatg accgtcccat tcatagaagc cactagctgg 708720
aataaggcaa cgatgagtaa tcacttcttt tttaaagaat ggtttttcca ataaagtttc 708780
acttcgcgca ttaataatta atttattatc aaaagtacta aagccccatt ttgccttttt 708840
taattctaat ttattatctc gatcaataat gattggtaca atattacttg gataataatc 708900
tttagcaatt aataaatcac gttcaaatgt atagtcaatt ctttcttcca attccatcaa 708960
ggcttttaat tctaaaaaat atctgccaca cataataatc tcctatttta ccaattcaca 709020
ttttaaaaac tctaagattt gcgcatttaa tgaatcatca ttttttatct cacttaacat 709080
ggcaacttca ttacaacatt caccacatat atcaatccca ataacatcgc cacgtttaat 709140
taaatctgct aaaattaatt taaattcaat taaccgcatc tgcccctgct gccaatcagt 709200
cgtgactact tgttcactta aaacatcttt atcaattgaa aaataaacag gatattgttt 709260
caaaagttca tcaattatct tccaaacttt taaatcacca agattattat cacacaaata 709320
aataacgcgc tccctatact taggatcgat taaatcaact tgttcttgtg caattccaat 709380
caaaatgatc tgttttaaat attgattatt ttttaaagca tttaagatcc atgatccaca 709440
gcttaaaata tccccaaaca tcggtttaat catatcacta tgatgatcaa agactattaa 709500
aataaaatca taatttatct tccttatcca aaattcactt acataatgaa aattacctga 709560
atcaataaaa tgtattcctg caggcagata atcacctatt cttttaatga tcttcgcttt 709620
tgcctcctca ctgcaataac cacgtgtccc cttaatatct aaacaatcaa tccaattaat 709680
atttttatgc ttataaaaac tttctaactc ataaatacca gtaaaatcca tgacagttaa 709740
tttcttttca tttacaatac ttaccccata aaaccagctc catttaatgc ttataacaaa 709800
aacattctaa ttcatgatca tcaacaatac ctattgcttg taaatatgaa taaatagtta 709860
ttgagcctac aaaactcatt cctctttttt ttaaatccat cgaaatatca tcagataact 709920
tcgttgttgt tttaaaatta ttatccttat ttttaataat ttgatggtta ctaaaacccc 709980
aaagatagtc agaaaaacta ccaaattcag tttgaatact tataaaaatt ttagcattat 710040
taattgctgc accaattttt cgtttacttc ttattatttt ttcatttgct aataactcca 710100
ttactttttt atcatcatag ttagctattt taattacatc gaaattatca aatgccactc 710160
taaaagcttc tcgttttttt aaaatagtta tccatgataa tcctgcttga aatgtttcta 710220
ataagaacat ctcatataat ttttcatcat cataaaccgg tacaccccat tcatgatcat 710280
gataattttt ataaatttct gacttttcat ctacccatga acaccttttt accatcatca 710340
ttctctcctt tttaactatt ttatcatgct tataagaata agcaaatatt acacaaaaaa 710400
actatcccag ttaaaatttc tcattcatca tatttaactt tttaaatatt ttttccagca 710460
gctaaaataa taaattatat tacttttaat attgtttagt ttttagtaca atgtttcaag 710520
atgttagagg agatttaaaa tgaataacaa taataatgat gtaacaaaaa aatatggatt 710580
atttacagcc attacaatga ttgttggaat ttgtattggc tcgggtatat tctttaaaag 710640
tgataatgtt ttaattgcta caaacggcag tattgcacta ggcgtgctat catttatctt 710700
agccgcaatt tcaatcattt ttggttgtct tacaatcggt gaattagcat ctcgcactga 710760
taaagttgga gggctaatct catatgctga aatgttttta actcgtaaag ttgcatgtgc 710820
tatgggctgg tttcaaacct ttgtttacta tcctacaatt acttctgttg tagcttgggt 710880
cattggagtt tatataaaca tattatttaa tttacaagcc agtttagaat ttgaaatttt 710940
aattggttat atctttttac tactttgttt tgtttacaat attcttttac caaaatttgg 711000
tgcttttatc caaaatagta caaccctaat aaaactgctc cccttattta ttttaggaat 711060
attgggaatt atttttggtg atcctattaa tggtttagca aatactagta tcaatacact 711120
aagtggtact gggtggattt ctgcccttgg tcccattgcc tattcatttg atggctggat 711180
cgtaacaact tctatatctc atgaactaaa agatgctaag aaaaatatgc ctaaagcatt 711240
aatgctaggc ccattaatcg ttttaagtat ctatgtttta tactttattg gtatctcatg 711300
ttatgttaca cctgaagtag ttatgacttt gggagatcgt catgtcagtt tggcagcaca 711360
aaatttattt ggtccagcct ttagtaaaat gattatcatt tttatagtta tttcggttat 711420
tggaactgtt aatggtttag tcattggcta tattcgcatg ccatattcat tatctttacg 711480
taaaaatatg tttccctttt ctaaacattt gcgtaaaatc gataaacgtt ttcaaatgcc 711540
cttaaattca gctatctgta gcttgattat ttgtacgatt tggatgttcg tccattattt 711600
atgtactaaa tacaacctat tatataatag tgatgtatct gagggagcta tcggaatatc 711660
ctatatcttc tatactttat tatatataag ggtatttaaa atgtatcttg ataaggaaat 711720
taagagtaaa tttaaaggtt tagtttgccc gattttagca actatcggct cattgattat 711780
cctatctgga ggtattcaaa ataaactatt tattttctat attatatttt gtattttact 711840
ttttctatac tcattatatt actatcaaaa aaataatcac taaataataa accatctctt 711900
agaatcaaga gatggtttat tatttataaa gttgattcat tccataaaaa ttcttctata 711960
tcttcataac ttgaaatctc tcgatcaaaa acataagcaa aaaattgctg caaattcggt 712020
atatcatatt gtttaaaatc cacaatatac agcatttcat atacttcttt cttcaaaatc 712080
cgtaaatctg aaataaagta acaccgcata agttttacag catcttcaaa aatatctttt 712140
tgcataatta accatccttt caagtcatat atctatttct tctctttatc ctaactccgc 712200
ttgatttgta atttcccatt gaccttatta acttcaaaaa taaacggatt tttctggaac 712260
cagactaaat cagcagcctt taaattccac tgttcataag caataataaa agtttgataa 712320
accagctctt cagcttctct tcgagtctct agagccgatt cgaaatttga atatgttcct 712380
aaatcaaaac gtttaccttt aaaaccaata ctagctcgat atttattatt tttcagttta 712440
taaataccgc atgctccact agtattattt ctttttaatt tttgtgagtt aataaactct 712500
atacatgtac catcaaccaa atgaagatta ttataaacac tttcagtaat ctcttttttc 712560
tacacccaca accgacatac tgcccgtgca ttagcccagt ttcactaact tctgtgttct 712620
tttttctgtt ggagaaattg ccataagtcg ccaaacttct gtcctttttt agccttgttt 712680
ttaggaatac agctacaatt agtgattgtc cctcgtttca gtttttttgt attaacaaat 712740
gttatttctc cacactcaca tctacattcc catactttat atcgagcttc taatttattt 712800
gtttcagcca agacgagtaa tttaccgtat tttctgccaa ctagactttt agtctttttc 712860
attaattgaa tttactttaa gcttagaagc agataaacaa atttataatt gaacaacata 712920
actgtgtcct catttattcg ttcatccctc ctcaataatt ctagtactaa taatgtaaaa 712980
ttgtgtttat atttgtcttg cacatagtac aaattcgtcc gcataaagta gacttattca 713040
ttcgaaaaga taaagcttta tttttaacga aaaaactata aaaacacaca aatttctttc 713100
tactatgatt aattttgatg tactatctgt caattttcat tatacatttg ttgaacgata 713160
aagtctacta ttttcataat aatcatcact tcaaatgaac ccatcttaaa aatgtatctt 713220
gagaaacatt aatagtagtg gctgcttccc ttgaggtgat ttttttattt aaccattttt 713280
cctttaaatc ataaaactct tctggaacag gaatgcacgg tctaccaaat tttacacctc 713340
tttttttagc agcctcgatt ccttcacgct gtctttgctt gatactttgt cgctcggttt 713400
cggctacata tgaaagaatt tgaagtacta gatctgcaat aaatgtccct gtaagatttt 713460
cttttcttgt tctagtatct agtagtggca tatctaaaac aacgatatct gcttttattt 713520
cttttgtaat gactcgccat tgctctaaga tttcttcgta gtttctacct agacggtcaa 713580
tctctttaat cactaaaata tcttgctctt tcaatatttt aattaattca ctgtacttgg 713640
gtctatcaaa atccttaccg ctaaacttat caatataaat attttccttt tttactggaa 713700
attgtgataa agcaataatt tgccttgctt cattttggtc ttttgaagaa actcttgcat 713760
aaccataaat atttgtcata aactaaaacc tcctaaattt atgcagtatt ataaaaatat 713820
ctgcataaat attattaaca agttatgata aatctatatt actgaatgta aaaaaagtta 713880
gtaataagtc gatgttacta actagctaga aatattatta ctttataaat tgattttaat 713940
gaataaataa tttattaaaa tcaaaacagg aaatatcaag ataggagaaa attatgacta 714000
aatcaaatac aattattgaa ttaaaaaaca aggtgtagtt gcagtaatta gaggaacaag 714060
ttatgaagaa ggtcaccaaa cagccaccgc ttgtattaaa ggaaatttaa aagctattga 714120
gattgcttat actaacaata atgctgacat gattattaaa caattatcag gtgattatca 714180
aaataataat actgttttaa ttggtgctgg aactgtttta gatgcaccaa ctgcaaaaaa 714240
cgctattatg gctggagcta aatatatagt atcaccagct tttaatcaag aaactgctat 714300
aatttgtaat cgctatggta ttccttatat tcctggctgt atgaccatta aagaaatcat 714360
tactgctatg gaatatggct gtgaaattat caaattattt ccaggaagtg cttttggtcc 714420
taactatatt aacgcaatca aagggccctt accgtatgtt tccttaatgg taactggtgg 714480
tgttaaccta aataatgcag ctgagtggtt taatgctggt attgatgcta ttggcattgg 714540
aggagagtta aacaaactgg cagctaaagg tcaatttgaa acaatcaaag aaattgcaca 714600
aaaatatgta aatactaaaa ctagaaaata attcttatat ctcaataata taataaaaaa 714660
ctattattta atattttgtt ataaaattag attataagag aactcccaat attactaata 714720
attcaaaata aaaatacttt ttgcggctat ctaacacttt gtgtaatcaa acttatcaat 714780
tgcagaaata aaagatttct gcaataaatt aaatactaat ataaattaag gagtaatttc 714840
tgaattgaat agaaactact ccctttaatt tgattgtaat tatttaaata gtataatact 714900
tgacatagtc ttatattctt atctataaaa cactttttat gattttaaaa atatttttat 714960
aaacgaatta tttaaataat ttttacatat taagatgcac ccctttcatt tgaatataca 715020
tgtccaagat tccaagtata tatcaaactt tggggtgcac ttcattttaa taagaacttt 715080
ttaactgcga gatacctata atcataaata ttacatttca caaaaactat attttttatt 715140
ataagttatt agagactcct tttttagcta gtctattgct acacctgcgc ttacataacc 715200
tgcaacagtg ttgactaaac tcaatccaga tgcccgtgca gttaaaacaa gcattaatct 715260
tgttcccgcc ggaacattaa tatttaagcc agttaatatt cccttagaaa tcgttcctat 715320
agaaattaca cctgttagtg aaggcgttaa tgttacagtt gttccaggca ctacagtcat 715380
agtgttgttt ggagcaattg attcatataa ttttgcttca atcgtaattg tacttcccac 715440
taatgataat gctgctgttg ttgaaaagaa tacatcgatt gaagtgatga ctccatctct 715500
tggcattgta aaagcaaagt ttgttaacgt gccagatgga ttggttaaat caattgtatt 715560
accaatgatt gatattcctg gtgctgagct accaaaccct ataaatgcag gggtacctac 715620
taaaccacca gcaatagttg ttaaagatac aggtaaacca gatgcaaatg gtattattgc 715680
tgaagctcca gctgctcctg ttgatccagt cggtccggtt gaccctgttg ctccggttgc 715740
tccggttgct cctgttatcc cagttggtcc tgtcggtcct ctatctccgt ttgcaccatt 715800
tgtaccagtc ggtccggttg accctgtcgc tcctgttgat ccagtcggtc cggttggccc 715860
tgttgctcca tcttctcccg ttgctccggt tggtccggtt ggtcctgtcg ctcccgttgc 715920
tccagtcggt cctgtcggtc ctgttgctcc gtcttccccc gttgctccgg tcggtccagt 715980
tggtcctgtc gctcctgttg ctccgtcttc tcccgttgct ccggtcggtc cggttggccc 716040
tgtcgctcct gttgctcctg tcggtcctgt tgctcctgtt gctccgtctt ctcccgttgc 716100
tccggtcggt ccggttggtc ctgttgctcc gtcttctccc gttgctccag tcagtccggt 716160
tggccctgtc gctcctgttg ctccgtcttc tcccgttgct ccggtcggtc cagttggtcc 716220
tgtcgctcct gttgctccgt cttctcccgt tgctccggtc ggtccagttg gtcctgtcgc 716280
tcctgttgct ccgtcttctc ccgttgctcc ggtcggtccg gttggccctg tcgctcctgt 716340
tgctccggtc ggtcctgtcg ctcctgtcgc tccgtcttct cccgttgctc cggtcggtcc 716400
ggttggtcct gtcgctcctg ttgctccgtc ttctcccgtt gctccggttg gtcctgttga 716460
tccagtcggt ccggttggtc ctgttgctcc gtcttctccc gttgctccag tcagtccggt 716520
tggccctgtc gctcctgtta ctccggttgg tcctgttggt cctgttgctc cgtcttctcc 716580
tgttgctccg gttgatcctg ttggtcctgt cgctcctgtt gctccgtctt ctcccgttgc 716640
tccggtcggt ccggttggtc ctgtcgctcc tgttgctccg gtcggtccta tcacgcctgt 716700
tactccggtt ggtcctgtcg ctcctgttgc tccagtcggt cctatcacgc ctgttactcc 716760
ggttggtcct gtcgctcctg ttactccggt tggccctgtc gctcctgttg ctccggtcgg 716820
tccggttgga catctaataa taattggtgg cctgcatcgg caacatggac accatataca 716880
accattataa ttacagtctt tcatcttatc acctccttta tgtgatctaa tataatatac 716940
gcaaatattt taataactac tgtgtcaata atctcataaa aaataaaaga ctaatttttt 717000
cattaaactt ctaaagtaat tatctaaata aaaaagttac tagatacata tgtaaatcgt 717060
atacccttaa cgccttataa aaaataatag tttatcatat tataataaaa ggacttactc 717120
ctttattaag gattagtccc ttttaaatct ttttttactt ctattcatca ttttcaatac 717180
gattaaaata caatttatta tgcaaatatg atggatcatt tggtttacat tttcctgcca 717240
attcattgta atattttgct gttttataat tacttagctt atcataacat aaacataatt 717300
gcatataggg aatataatca taacaatctg gagatataaa tgctccagat gtatcatcac 717360
gctcacacga taatgctact gcactccaat agatagattg ctcatactgc ttcaattcaa 717420
agaaatactt acctaaatca cagcatatct ctgctcttgg caaatcatag caaagactat 717480
ttaaaagcca ggttattgct tcttgcatat caccaagatt gtaaaaacaa tagcctaaaa 717540
attgacaggc agaaatgtta ttttctttcc atcccttctt ggtatttaaa aatcttttaa 717600
attcagctac tgcttcttga tacaattgat gataaaacag ctcccgagca taatagaaaa 717660
tttctcgtgg actaaacatt accccttcat tcaatttttc tctaaatatt cttaaattac 717720
gattaacatc actatttttc accttactat gtgtaattgc aagatcacta taaagcacct 717780
tacctctagg acttattact tcatgtataa atccttccca ataaaaatta tcctttcttc 717840
ttaataatct ttcacgataa tacgtaaatg tcggcttatt attctgatca aattctgcat 717900
tatatttcat cataactaca gaagtatctt ttgataaagt ttttttaaga ttaatcaaac 717960
cttcttgatc gctatctgaa ataatatcat ccgcgtctaa ccacatgcag taatccatag 718020
ttgcctttga aaatgaataa ttccttgctt tagcaaaatc atcacaccat acaaaatcat 718080
atactttatc agtatatttc aatgctatct ttttagttcg atcagtcgat ccggtatcca 718140
caatgattat ttcatctgca atcctttcaa ccgattttaa agctctctct aataccattt 718200
cctcatcttt tacgatcata cacacactaa tagttatcat atatttcacc actataatat 718260
atgtcaacaa cccttaaaat gtgaaaatat ttaaaacaaa aaatgttcta aataaagaac 718320
atttctaaat aatcttagtt gagcattctt ctaaattaat tacttcatca acaattggta 718380
aataaaattc cggttcatga ctaactaaaa taacagctcc tttaaaagcc ttgattgcgc 718440
tttgtaaaga atctttagca tcaacgtcca aatgatttgt cggttcatct aacaccaaaa 718500
cattagcttc acgattcata atcttacata atctaacttt ggcattttct ccacccgata 718560
aaactttcat taaagattca atatgatcag ttgttaaacc acacttagct aacatagctc 718620
taatctcacc attgtttcga tctggaaatt cctcccacaa atagtctaat gcagtttggg 718680
aaactgcaga ttcttcttgt ttaaaaaaac caatttcaac aaatggatct ttttctactg 718740
ttccactata aggtttttgc atcccaatca gcgtctttag tagagttgtc tttcccaaac 718800
cattgacacc tttaatagca actttcttat ttctttcaaa aacaagattc atttctttcg 718860
ttaaaggact atcatatcca atcactaaat ccttacaatc aaataatact ttacctggtg 718920
ttctagcttc tataaaagaa aaagtcggtt ttattttttc ctttggttta gaaataagat 718980
tcatcttatc taatttcttt tgtcgtgaac tagccatatt acgagtagct acccgtgctt 719040
tattacgtgc gataaaatct tcaagatcag caatttcttt ttgctgcttt tgataatcag 719100
cagctaactg acgttttttc aattcaactt gttgtaaata gtagtcataa tcacctttat 719160
aacgagtcaa tacaccatct tctaaatgat aaataatatt aataacttga tttaaaaaac 719220
taacatcatg actgactaaa ataaaagcat tatcataatt ctttaaaaaa ttgattaacc 719280
aattgatatg ctgctcatct aaatagttag ttggttcatc aagaattaaa atcattggat 719340
tctctaataa taatttagtt agtaaaactt ttgaacgttg cccaccagat agcgcatcaa 719400
ccggtttatc taaaccaata tcattcaacc ctagaccacc tgcaacttct ttgattttaa 719460
catcaattgt ataaaacccg ccatgatcta aaatttcttg aatttcacca acttcttcca 719520
tcaactgatt catcgtttca tcatcacaat cagccatttg ttcatacatc gataacatct 719580
ccgcttctag atcataataa tatttaaaag catcttgtaa tgtttcatat atagtttttc 719640
ctgggtgtaa agctgtgtgt tggtctaaat aacctgttga aattctttta caccattcaa 719700
tctttcctga atccggagca atcttaccag taataatatt taaaaaagta gatttcccct 719760
caccattagc acctactaaa ccgatatgtt cgccatttaa taatctaaaa cttgcatttt 719820
ctaaaatagt tcttccacca aaatcatgac tgacattttc cacacttaat atactcattt 719880
tctacctcaa cttgcaatat taaaggaaga ttatcatctt cctaattcaa ctatattata 719940
cattaaaatt actaactgtc gagtctaaac aatcactcaa ttgaaaagcc atagtatcca 720000
ttctttccat tctctttaac ataatataaa taataatctg cattattaat taattcctct 720060
ttagataaac aattactaaa agaattataa tatccagatg aaatagtgat tttatcatac 720120
ccatataact caaatttact ataaacttgt tcaataaaac taattatcat ttgctcatta 720180
caatctacac aaatacaaat aaattcatca ccgccaaaac gacaagaaat tattctatca 720240
tcatcttgtt gtaaactatc agcaaaatcc tttaatattt gatcaccagt taaatgacct 720300
aaactatcat tgtattcttt aaaatgatcc aaatcaaaaa taataattcc taatagtcga 720360
cttttatttt taaactcact atatttataa tgaaaatatc gtcggttata aatcttagtt 720420
aaatcatcta gtctagactc cttaacgata tctttttttt cttccattgc tttaaatagt 720480
tcaattttat ataaaacact atttaaacaa aaatcaatac tttctttttg attttcatgc 720540
atcaaataat aatattgttc atataattta ggcaactgtt ctttttcttc aaaaacaata 720600
caatacttta tcttcatttc taacatttca atttgataac gcattccagt tttaccaaaa 720660
tcattctcct ttaataaaag ataaagacat tttgtccgct ccttatcctt gattgcaaaa 720720
gtaatataca ataaaatatg atgaataaaa taaattgctt catttgcacg aaaaccatga 720780
atctcattcc ctaatatatt atcaataaac tctaaagctt ttgctacatc accatgccca 720840
tagcaaatta atgcttttaa tgcttgccat aaccgatcaa tcggatcaaa tgaagtatca 720900
ttaaataaat ccttattttc ttccattaga gcaattgctt gatccaatct tcttttttca 720960
caataaatta taataagata acataacaca aaacgtttta ttttatattc cggcagttta 721020
ggagaaatct ttttgatctg ttcaagcgat tctaaaaaat aaggtaacgc taaatcaaat 721080
tgacctaaat taacaaaaac atctcctaaa ttacagttaa attttgcttt cattatatag 721140
tcatttaact gctcagctaa cttcaatcct ttgagataaa aaccagtagc aagagaataa 721200
tcattattac atactgcaat agcatatagg ttgtaagcct gcatcaataa atctggatac 721260
cctttttctt catttagagc caacatctca ttcgctaatt taactgtttc ttgttgcgat 721320
ttacaagaat aatagtaatc gattatgtaa ttactagcta aacataatat gtaatcatct 721380
ttttgttcta gtgctatttc ttttaactgc aaacattttt gatacatttt ctcgatatca 721440
tcaaactgta aatgacggat ttcttcgact aaacgatcta tctcacgcat taatttctcc 721500
tttctttaag cactttgatt tcattataac ataagatagt tctaatattg gttaaaaaat 721560
tcctagtttt aactaggaat cgtatatcta attatttaaa aaatgtttta taatcttcat 721620
aatttttttt caacaattca ggtgtattta atccatacgg acaatgcgac atacatttgc 721680
cacaattaat acaattttct atttttttca tttcttcttg ccaatgttct gacaaccagc 721740
ctgcactagg agctcgtcgt aacatcaaag acattcgagc acactgatta atttctattc 721800
ccattggaca tggcatacaa tatccgcaac cccgacaaaa ttcaccagat aactcttttt 721860
gatcatgagc aattatcgct ttgatttctt cactcataat tggtggatta tcattatact 721920
caataaattc atctaactct gattcttttt gaattcccca aatcggcaat gtattatcaa 721980
actgcgctaa atacgcatat gccgcatcag aacggtctat taaaccacct gacaaagcct 722040
tcatacaaat aaaaccaaca tctttttctt tacataaatc aactagttcc tcttcctttt 722100
ttgaagccaa ataactaaaa ggaaattgta aagtatcata taaaccacac tcaacagctt 722160
ctcttgctac atgtaaacga tgattggtta aaccaatata tctaattttt ccttgtttct 722220
tagcctctag catagcttca tataaacctg atccatcccc tggcttagga caaaacgacg 722280
gattatgaaa ttgataaata tcaatgtaat ctgtctttaa taacgataaa cttgtttcta 722340
aatccttcca aaaatccgtt actgtcgttg ccatcgtttt tgttgaaata taaatttttt 722400
ggcgtacctc actaagagcc tcaccaatct tttcttcact atcactataa gcccgagcag 722460
aatcaaaaaa agtaattcca ttatcatatg ctttctttaa aataactttt gcttcttcca 722520
tatttactcg ttgaacaggt aaagccccaa aaccatttcg attaacaaca atatttgttc 722580
tccccaatct tactgtttcc attttcatcc tcctacaatt cgacatttcc tatttttatt 722640
atactccctt gagtaaactt taagtcaagt aaaaaacgaa aggttttaac ctttcgtttc 722700
atcaaaatta tgattaataa tttctaataa tctgaactca ttatcttcaa attcaaattt 722760
taaaatacaa caattcttca agccgccttt ttggtcaact tgactagttt cctgccaata 722820
tctcataaaa ccacgacatg ccccaccatg agaaactgca agcacaactt tatgatcttc 722880
cttctgcata atttctaata atgtatcagc aattctttgg cgcatctgta attctccttc 722940
accgccataa ttgacaaaaa aatcaccata tggcagcggc ggatttaaat cttcactttc 723000
accttcatat attccaaaat tccattcctt tagtcctttg actcggtgat aaggtaaatc 723060
acagactaac tctaaagtat cacacgcccg ctcagaagtt gaactataag catgatcaaa 723120
aacgatgtta ttgtctttaa aatattttcc tgctatctta gcttgtttaa ttcctaactc 723180
tgtcaaaggg gcatcacacc acccttgaat ttttttacga gcattaaata gcgtttgccc 723240
gtgacgcatt aaatatagag tcttcttcac ccgatcagtc tcctattttt actattttat 723300
ttgtggaaaa accacaacca ataacatttt aaatgcttct tgaccatata cagaatgcgg 723360
tttattagcc ggcataacta atgtttcacc acgctttaag acatattctt gaccatcaac 723420
tgtaaacttt ccaacaccct ctagcacggt taccatcgca tctccgctag agccatgcgt 723480
tccaatttct tcacctttat caaaagaaaa aatagtaata cttaaagcat cattttgtgc 723540
tagtgtctta ctaactactt gtcccgcttg aacttccact tgcgatgcta atgtagttat 723600
ttgttcatgg ggaatatttt taataaatat atcgctcata tcttacctcc tatcaatatt 723660
tattcccaag atatgtttat attatagcat aaaagttaaa taaagcgatt aacgatactg 723720
cttcacttta aaatgatagt ttactatctt attaagataa tctaaatcat ttaaatcctg 723780
aataaatctt gtggttagct ctaagtcaag ataaaataaa aaagtgtaat ctcgtttttt 723840
atttatataa aaagcgagga ttgatcatta ataagaagtt ataataaaga gggtaatata 723900
aatggaatgg attgaacggc taaatacaac aattgaatat atcgaaaatc atttaacaga 723960
aaaaattgat tatgagcagc tcgctaaaat agctggctgc cctagttatc actttcaaaa 724020
aactttcctt tacatgacta atatctcatt atcagaatat attcgcaaac gatgtatttc 724080
tttagctgca gttgatttac aaacaggaga agacaaaatc attgatatag ctttaaaata 724140
tggatatgaa tcaccaaccg cattcaaccg tgctttccaa gcagttcatg gaattgcacc 724200
ctcacttgtt agaaagaaaa atgttcaaat caagtcattc ccagctctaa aatttacctt 724260
ttcaattcaa ggtcttgatg aattaagttt tagaattgaa aaaaaggata gctttaaaat 724320
cctaggaatc agctctcttt taagtaaaga attactagaa aactttgtcc aaatccctaa 724380
gcaatgggac aaagcattaa atgatggaac ccttaaccaa ctttatcgac ttaataatca 724440
gactccgcta ggattattag gagtcaatat tcatcaacac gaagactggc gttatttcat 724500
tgctgttagt tcaactaatc ataatcaaaa ttttgaagaa tatcatatcg gcagcgctac 724560
ctgggccatc ttttctggtc acggaacaaa tagaactctt caagagcttc agcgtcgtgt 724620
tattacagag tggttgccta cttccggata tgaatatgct aatatcccag atatagaagt 724680
ttatctaaaa gccgatccaa atgatgccat ttacgaatac tggttaccaa ttataaaaaa 724740
ataaggagtt atgttatggt aattacaaat attaaggcct cttttcctaa cgatataaaa 724800
actatttgga atattgttac ttccctagat aattatactt ggcgcagtga tctttcaaaa 724860
ctggaaatta tcaaatcaca agagcaattt atcgaataca ctaaaaatgg ttatccaaca 724920
acttttacga ttacctgttt tagaccctac cagcgttatg aattcagtat ggaaaacagt 724980
aatatgaaag gtcactggat aggattattt tcatctcaca atggtattac ttcaattgat 725040
tttacagaaa atatcacacc taaaaaattc ttcatgaaac cctttgtcaa aagatattta 725100
aaaaaacagc aagctgctta tattcgtgat ttaacagctg tcttagaagc aatagaacat 725160
cgattttaat aacaatccca attatacaag acttttgaga aattcttatt ctctaagtct 725220
ttttttgtta taaagaaatt acaaatacca ctatcccccc acataatctc tttatcacca 725280
atacctacac tatcaatttg tagtaataaa atataatcat cgtacttttc actactgcgg 725340
gggtcttctt gagtaaatgc aggatatcca aacattttat gcccaaaacc gctaaattca 725400
ttaaattcat cctcatacaa aatttcatcc ggtaaatcat aatatgatga aattaaatta 725460
tttgggtata agttattcca ttcttgtgta aataaaccat caaaatgata atcaccaata 725520
cttattcctt cttcgccacc aataaaatgc agcttaaagt tatcaactat tggaaaataa 725580
ccctcacctt caggatgata tttattaagt atctgacttt cagatacagt tttatcaata 725640
cttgaataat aaataacccg actttctgct tgcgatatca tattctcaaa atctaaacca 725700
taaagatcat tatccatagc ccaaaattgc aataaccctg cttctaattg ataactattc 725760
atcggtaaat cagcaaaatt aatttgcccc agcaatcgta attgtttatt atctgtactt 725820
aatggtactt cgtcatctac tcctaagtat ggtaatcccc caaatttact atcaaaaata 725880
ctacactcat cattacttaa ttcaatttta ataacatctc tttgagtata gtctgtaatc 725940
accttcatcg tacttaaaaa catttcttta ttcatttcta gttttcctga ctcttcgact 726000
gaatcttttt tctttttaaa aaaatcaaac actcaccatc actcctttca ctaaaacata 726060
aaacagcagc ttccattatc atttctttat ttaattttag caccttctta aaaacaagca 726120
aacaaaaaac atctcgataa tttataatcc gattaccgaa atgcttttta aatatctaaa 726180
aattataatt ttaaatcatg catggcaatt acttcgacca ataaagcaat accaccaaca 726240
agtaaataag cagctacaat ataatttaat acgacggttg acatcaatgg cgcaataata 726300
aatgctaaag ctgctaaaac attgattata cccgtaaata taacccaacc ataactttca 726360
attccaaaaa agcttaattg atgagcaaaa ctcaacttat taagcccata aaccattaaa 726420
ataaatccaa aaataaaagc aaatgtatta attgtcattt caattggtga acatatcaac 726480
aaaagaccaa ttaataaatt acaaatagcg cttacaaggc cacctggacc acgaaataat 726540
ggtggtgccg ctatataatc aatgatctga taaattccta aaataagaat taacccggtt 726600
gcaatcgtac caattatagt aactgatttt actggataaa tcatgcatag aatagcacaa 726660
ataatcatta aaatagcaac aataattcct gctactctta atgagtgaat ctttttattc 726720
cactttccaa caaattcact tcgaaaatca aaatcatcat taaatcttaa catctctatc 726780
accttctata cttatattat agtcttcaaa aaataaaata atataaacaa atttgtcctt 726840
ttgtctaaaa aatcctatac tataattggt ttattatgtt cagatacggt atattaagca 726900
ctgcttcaat cattgatcgt tttattgcag ggattagaga aagccaagat agctatgttc 726960
aagcaattgc atcaagaaat ttagaaactg ccaaaaaagc agcaaaacga ttaaacattg 727020
aaaattatta tggcagttat ggtgaattgc tttgtgcaaa taatattgat attgtttata 727080
ttcctacagt taacagtcaa cactatgaaa actgcaaaaa agctctaaaa caccataaac 727140
atgttattgt agaaaaacct tttgctttaa ctgtcttaga agctaaagaa ttattcacat 727200
tagctaaaaa aataattgtt ttttaatgga agcacaaaag gctctctatc ttcccacaac 727260
aagtaaagtt aaagaattaa tcaatagtga gataatcgga aaaattaaat acttagaatt 727320
taaggctggg tttccaggtc gctttactta cgatcactgg atgtatgatc tatcattagg 727380
tggtggtgct ctttatggaa gtgctactta tacaattgaa tatctccaat atctttttga 727440
tcatccaaat ttaacaattg atggtacatg tatcaagtgc tctactggag cagatgaaat 727500
atgtaatttc caattgaaga taaataatag tattcttgct tcttcaacaa tcgctatgaa 727560
tgtggcatta aaaaatgaag ctgtttttta tggagaacta ggttatatcg ttgttcctaa 727620
ttattggaaa tctaatcagt tagatcttta tctcgatgat ggcagtcata gtcattatga 727680
ttttccttat caaagtgaat ttgtttatga aattgaacat attcatcaat gtattaataa 727740
tggtcgatta gaaagtccta tcatgaataa agaaaaaact attgaaacaa ttaaacttgt 727800
tgaacagtta tatcaaaaat ggaaataaaa gaatctttgc cataataaaa tgaacctcca 727860
ttacttgtaa tgtgtaccct ccttactgat ttgttcagta aagagggtac acatcattgg 727920
gtgtccaaat aatggaagtt catttcaaat tagaactaaa actttttatt attagtaaca 727980
gtggcataaa aagccacccc caaaataatc actcctccaa gcagttcctt tactccagga 728040
atctcatgta acaaaaatat cgcaaaaata atgctataca cactctccat tcccgatatt 728100
atccctgcag tttgcacctt tactttcttt aaactactga cataaatgct atgagcaaca 728160
gccgtacata taactcctag aaaaataagc gcaaataaat caagttttgt tattgaagct 728220
ttaactatca gcaatgacgg taataatata atcgcagcaa ttccttgttc atataagcaa 728280
atcgttctcc ctgtatattt acctgcaaaa tagcgattca tcaagcataa caccgcataa 728340
cttaaagatc cgattaatcc aataaagatt cccagtgtta tttgattgtt aagtgagaac 728400
tctggaattg taattattac cccagcaaac attgttagcg caatcattat attttttatt 728460
ctaagctctt catgatatac tagcggttct aaaaaagtca caaaaagtgg aaaagttgaa 728520
aaagtaattg ttccaattgc aacagttgat aattgaattg cttgtaaaaa agtgaaccag 728580
tgaagtgcca taacaatacc agcagcgatg attagaatat aatctttttt attactcaat 728640
ctaactttct ctttttttat taaaattatt attaatagaa aaattgaaga aaaagatact 728700
cgtccaaagg taatcaaaat agctggtagt gtgacaaatt ttccaattac tccggctaag 728760
ccaaataaca taacagccaa atgtaataat ccaacttctt ttttcatcac tttcccctcc 728820
tatttatagt taataatagt ttagctcatt tttaataaga aaaaaagata aaccacctat 728880
atcatcgctg tccattttct aaactaaaat gcaaggccaa taactactta aaaaccttca 728940
ttataattag ttattaataa aatatttaat tcgttcaatc gttgactgag tttcaagata 729000
ttcaggatac agaacttcaa aaacatgtcc taaatgtttt ccttagagca acacacggtt 729060
caaacatacc agttataagc cttcaataca tttttagcct ttattgacta aaaatgtaag 729120
ttatctcact actaataata cgtgttgaaa gtggcggtaa ctatcaatta catcaataag 729180
gcaagctttt cgatatatgt ctgaatcttc attgttaact ccctgaacca taacactaac 729240
ctactgataa acaaaatttt tactgttagt caaaacttat taaatcatct ccaccatgta 729300
acaaaactct ctaatcataa tttctggtgg ctgaacatta tatactttac agagctcagg 729360
ctgttttatg attgcataaa ccaatcctgc taaatgccca ccagctgaat cactcagtaa 729420
aaataatttg atcaatattc caaaaatatt tattctttgt tttagcaaca aactttaaag 729480
tcataataat ttcctgaact tactgcttca acgaggcttg tggtattaga gtataattta 729540
tattcacaac agtaaaattt ttagcagcta gcataactgc aaatttttat ttactccttt 729600
atcaccataa atccaggcat caccgtgaac atcaatgatc atagacaatg gcttagtcgt 729660
ggattaagga taataaatat ctagtaaatg attatgattc ctgtcatctt gataaggaat 729720
atcaactact tagtggacat tttcgagaat agtaaaaata tcattacttt ttggttgcat 729780
tttaaaacga gcaaacttaa taattgatgg ataaaataga tttataccta tcatctcctc 729840
attgaattat taataccaca ctattatgat actctttagc cccattttct ctatattatc 729900
gtaaaaaaag catcattttt aaaatgatac cttttaaata acatataaaa ttatacataa 729960
gaaatgtaac acacttccta ataagatcca taaatgccaa atactatgca tatagcgata 730020
cttattttgc aaaccataaa aaacggtacc aatcgtataa gctacaccac cagccacaag 730080
taaccaaatt ccattatatc caatagcttc cggcaataga ttgaatttaa agataataca 730140
ccagcccatc gctaaataac aaatcattga aaacttttca ttactttcaa tatcaattgc 730200
atttaaaatg attcctagaa ccgtacagcc ccaaacaaca gcaaagatca tccaagccca 730260
aaatgaatct actggtctta tcgaacacaa cacaataggt gtataagtac cagcaatcaa 730320
tacaaaaatt gaacagtgat ccataatttg aaacactttt ttactcttag tatttgggga 730380
aagcccatga taaatactac tcattgtata tagcaagatc attgatattc cataaataat 730440
tcctgaagct ataccataat tgttatggcg caatactcca aaaacaatac aaagtactaa 730500
tacggcaatt ccaaaaactc cacctacaat atgagtaacc atattaaaaa tttcttcacc 730560
tcgagtatac tcgggtaata ctcgatcatc taattttgtt cgtttcattg aataccccca 730620
atctatatgt atgaatatag ccctatttca tgttaatttc aagaacatca tataataact 730680
tcttataaat ttctttgata aaaccaaact tagtcacagt atttgcctgt cgattgcaaa 730740
aatattgttt tgctaaaaat ctttaattat ccatttttac cttactgcta taaaatattt 730800
agatatttaa caaattaaac taaataatca tattttctaa ctttattatg acaatgtata 730860
cagctaaaag atatgtgttc cctccccgca aaataaataa taattaaaat taccatgctg 730920
gattccacaa tagcgataac cagctttttg tatttgttta aacagtttga tttattttca 730980
tccttcaaca aatagttttc aataaaatca tttaaatttc tatgataagc actaatataa 731040
aagttcacct atttttattc catatcccag tcttgtcctc aaatatataa ctgttttgaa 731100
gattttctac tattttaatt tctttattaa aattatttat actgtaactc tcttttaaat 731160
tttctaattt gactaataaa tagatcatta ttttgtaaag aaatataaaa atctttttgc 731220
tctgtaacaa tattgagccg atccaaagaa ttagctgatg atgcaattgc atcacgactt 731280
ttctctattc ttataatttg ttgataataa attccaaaat cttcagtaat ccccctttcc 731340
ttttaatcct gattaaaata gtctttaaac aatttaattt attataacac cctaattagc 731400
tgattcatca tttctatcac ttaacgattc ttcatcataa aaatatatct taaaaagacc 731460
atttgactca aattctcatt tttcaaatta ctcctttatc gatataagta tatattgcta 731520
atcataacaa aacaaagata ttctaatttt gtaagtaaaa ttaccttgct tgattacttt 731580
accatcctta gttaattcta aaacaaagac aatcactatc catatcctca atctaattat 731640
attatctcat aatcaataat ctatcacgaa ttaaaagatg cctaacggca tcttaaactg 731700
ctaaatcaaa ttatctagtc ttttccatca aataattagt taaataaaca ttatccactt 731760
tgactgactg ttctttaata actttatatc ctcttttttc aaaaaaaggc ttagcactta 731820
tggaagcatg aactgttaaa ctttttacat ctttacaata ctgttctaac ttatcacata 731880
gctttgttgc aatctgtttt ccttgataat ctttatgtac gtataaatga tctaaataac 731940
ctctcttatc aatattacca taacccaaaa ccttttcatt ttcaacagct acaagagtat 732000
acatagagtt aaaaaagtca tcttgagtca gcagaaaatt actccgattt gaccatactt 732060
tgatttgatc attattgtaa tcatatctat ttattgtatt aatcgtttca taaaacaatt 732120
cacaaattac ttttaaatcc gaagactgat attttctaat ttccatcgat ttcaccatta 732180
ataattttat aaactctctt ttttacttca cctaaatctt ccttacgtaa taaagggaga 732240
gatcacatag tttttcttat tcataatctt atcattttaa ccatcccaac aattcgatca 732300
tttcattacc aaaacattct tgtctaaaat gagccgaatt ctctccaata acagaatatg 732360
ctgaaatatc tttcattaca actgaatgaa ttacaataat ccttccatca tcattttggc 732420
gcataatcat atttaaaatt accattaaat atttatatag taaactgcaa ttatatcatt 732480
ccttttactt ctttaattaa attaaaattc cattacaatg atctatttca tgttgaatga 732540
tctgagctgt ataattacta aaagttttta ttttcttttt gaaatcaaca tcataatatg 732600
ctacttttat cttttcgtat cgctttgtct ttttcactcc aatatgtgat agacatcctt 732660
cttctgtttc atataaacgt cccatagttt ttataatttc tggatttaac attactaaat 732720
aattaccatc atcgtttaca atgataatat ttttattgat accaatcata ttagctgcca 732780
ttcctacaca acctgtagca tgagctataa tcgtatctaa taaatcttga acaaccggta 732840
aatcctcttt agtagctgga agtgattttt gacttagtct aaattgatca ctaactattt 732900
ctcttatcat ttattttccc ctttatattg tcttagcaaa gcttgatgtt tctttaataa 732960
tgaagctgaa tatactttct ttcctggctg atctctaata accttccaca atatcgaagc 733020
agctttcaat ttattataat aaattttatt attttcatca cgacaaaaat cttttaaaaa 733080
ctgattccac tgacaagctg aattatcata tttagcataa tcactttttc cataatacac 733140
atctaaaaga tccttgagcg tgaaatgaac attcccctca cttcgaaccc ttctcaatgc 733200
agttgccata tctgcggtga acttaaaatt aggtgttttt gtaatttcgc caaagaattc 733260
acgaaaacgt ccattaagaa caaagccaca ttctaataat tttgtttcta aggttaaagg 733320
cacatcttgc ttccttattt tcattcgttt tactggttta attatttcac cattaaaata 733380
ggctttaata ttatcattca gttccgtttt agtacctgta tgagtaattc cgtgttcttt 733440
acaaatttgt tttagttcat cacgatacca ataatactgt ttaaattcat caaaactttg 733500
aatatcatta aaatttggac gtgtcattta tattctccac ccctgtcttt taatatcata 733560
tcatctatag ctatttatct caataaaacc atatatcatc tttatatagt tcaccccctt 733620
agttggaaat ccaactaaga ggttcaattt cattattatt aaaaatcatt tagataaaca 733680
gattagcaca catagtgaag atagaacaaa ttatgattcc ggttacagct ggaactaaga 733740
aagatacaat cgcccatttc caactattag cttctttttt tattgttaaa agtgttgtcg 733800
aacaaggcca gtgcattaat gaaaataaca ttacattaat tgcagtgatc cacgtccagc 733860
cattttctac taataaactt tttaacatta ctaaattatc catttcaatc aaactaccac 733920
tagcgaggta tgccataatc atgataggaa ttactatttc gttagcggga aaccctaaaa 733980
taaatgctaa caaaataacg ccatctagac caatgcattt agcaaaggga tccagaaaat 734040
tagaagtaat atttaaaatt gtcataccat caacactaat gtttgccatt aaccaaataa 734100
taagaccagc aggagcagct actgccacag ctcgagataa aacaaataat gttcggtcaa 734160
aaattgatct aacaatcact ttgccaactt gaggtttacg atatggtggt aattctaaag 734220
taaatgaaga tgggactccc tttaatatag ttttagataa taactttgaa ataatcaaag 734280
tcatagttat tcctaaaaca attaacattg ttaaaaatat tgctgataat agagaatttt 734340
gcatagttgc ttcggttcca ataaagaaca ttgttaagat tgctatcaag gttggaaaac 734400
gaccattaca tggcacaaaa ttattagtaa tcattgcaat taatctctct cgtggtgaat 734460
caataatccg acatcctact attccagcag cattacatcc aaatcccata cacatcgtta 734520
aagcttgttt accacaagcg ctgcattttt taaatgcatg atcaagatta aaagcaattc 734580
ttggtaaata gcctaaatct tccatcaaag taaacaatgg aaaaaagatt gccattggtg 734640
gcagcataac acttacaacc caagctaaca ccctatatac cccagataca agcatatcac 734700
taagccatag cggcgtccca ataaaatgaa agaactgatt aaaaggtact tctaatccaa 734760
ataagaaatc cgataaccac tgcgatggat agtttgcccc tgttatagtt atccaaaata 734820
ttaaagcaag taataaaatc atgattggat accccgtcca gcgatttgtt aaaatcttgt 734880
ctatctgacg atccctttga ttataatctt gcttttgata gtgaaccact ttttgacaaa 734940
tcaaatgagc actgtgaata aatgaaacaa caatcttgtc ttgtaaatta tccttattta 735000
tatcatgttg tgctaataat tcatttgctt ggtcgatagc ttctttaagc tcttgatcat 735060
cgtagtccag tcctaattga tttgacattt caatcattaa ggaaggatcg ttttcaatca 735120
atcttaagct aagccactga taacttaaag aagtagttac tttcttttgc aatacttcct 735180
caacaattct tattgcttgt aataaaatat cactataagc tatttttaag gatttgtaat 735240
taactggtct atcgattgct tgatctaaag aatcaataac tttatgcaaa tctgtctttt 735300
ttctggcagt aatcccaatt acaggaactc ccaagcaaga tgataattgc tcaagatcaa 735360
tatcaattcc ttttttctta gcttcatcta acaaattaac acaaactatt acatttgtat 735420
gaatttcaat tgtctgaatt actaaattta agttacgttc taaacaagtt gcatcacata 735480
caacaacaat tacatctgga tgctcaaagc aaataaaatt acgtgctact tcttcttccg 735540
ctgaatgtgc taataatgaa tatgtcccag gaatatctac taaaacatat gaattttctt 735600
ttcctcgaca atagccttga gcattagtaa ctgttttacc aggccagtta ccagtatgtt 735660
gatgaaggcc tgttagccca ttgaaaacag tgctttttcc aacattagga ttacctgcaa 735720
tggcaacaac tttatcattt ctactttgtt tttttattac taactttgtc tcacttgcat 735780
taattcctgt agatttgtta gttaagccca taattcacat catcttttct aattaaaaca 735840
ttttgacaat cttcattccg taaagcaatt actgcacccc tgatcaaaaa agctttagga 735900
tcttgacttg gactattcaa aatacattgt acttccgtat catcaactaa gccaatatct 735960
aaaagtcttc ttttaatact cccttgtgcc attaatgaag taatcactcc tacttcaccc 736020
atttgtaaat catttaaaca tctattttct atcataataa atttctcctc atcgtatatt 736080
agattaagga aactttgttt cctaatacta taatattaaa ttactagtaa agcgttacta 736140
aaaaggagaa aaaaatgaat aacgatgaaa atgcctattt tactttcaag ggctatcaat 736200
tgaataatga cagtaactta acttcttcaa tggaagatta tttagaaatg atcattcgct 736260
taaaagaaaa acaacccttc gttagaatca acgaattggc caataatctt aatgttagac 736320
cctcatccgc ctctaaaatg gtaactaaat taagtcaaga aggcttttta gaatatcaaa 736380
aatatggaat tatcacgtta actgaattag gtaaacaatg gggtgaatat tttatatatc 736440
gtcatcaggt attaaataac tttctctgtc tactcaataa cagtcataac gaactagaac 736500
aagttgagaa aattgaacac tttcttaata aaaaaacaat tgataattta gccttgctta 736560
ctaaagaact tcacaatcta caataaaaac aacaatatgg gaacaaatcc attaccatac 736620
tgtcgtctta ctttttatcg aataaaatta gtgaatttat gctcctcttt ttccggtaat 736680
ccaaattcct ttttacctaa ttgaatactt ttaattaaaa aagccatatt cttaccaaga 736740
gttctcatcg tttgtagtcc ttcaaggtcc tgctgtactt cttctggtga attaccatgt 736800
accatattcc aatattggct agaggctatc ggcatttgag aaatagtaaa atatttattt 736860
aattcatcaa atgtagcact attaccccct cgacgacaac taactacagc cgccccaact 736920
ttcattgttt tatcagcagt catactataa aataaccgat caataaatga tactaaggtt 736980
ccatttgccg acgcaaaata aactggtgaa ccaataacaa taccatcaca ttctttaaat 737040
tttggtgcaa tatcattaac aatatcatta aatacacatt tccctttcgt cttacattga 737100
cgacaaccga tacatccacg aatatcttta tgaccaacat gaataatctc agtttcaatc 737160
ccttcactct ttaaggtttt tgatacttcc tctaaggctg tatacgtaca tcctttagca 737220
tttggacttc cattaattaa aataactttc atttttctat cctccttgat ttctcttttt 737280
atttatctta caattatatt gtaatactcg gtagttacta ccggtcaata attttttaaa 737340
ataaatcaaa aatagaggta tttattatgt gtacgatgaa agaagtatgt aaagaaattg 737400
gtatgaatta tgaaacatta aagttttatt gtaaagaagg tcttgttcct aatgtaaaac 737460
gagataaaaa taattatcgt aattttgatg agaaaaatat tgcctggtta aaaggaattc 737520
aatgtttaag aaaatgtgga ttaggcgtaa gtgaaataaa aatatatatg aattattgtt 737580
tacaagggcc aacttcaatt ccccaacgta aagatatgct tagccaaaca aaagaacatt 737640
tgttaaaaag aattgcagaa ataaatgagt gtattgaata tatcgataat aaacaaagct 737700
tttacgatga cgtacttgaa ggaaaatgca ggtacacaag taatcttatt gaaataaatg 737760
agtaaatagc tttgataatt accactttaa gaaaataagt ctttatcttt tgtcactaaa 737820
agataaagac ttatttctat attagaaata tcctactctt cttcaataaa atcaacacat 737880
aattttgtaa ttccgcttaa catataagag ctggcttctt taatataata aaattcaggt 737940
aaaaattctt tatcaataaa agaggatagc acatttttta cttcatccat atccggtgtc 738000
attggtgaac ttatcactac agcttcgggt ccaatgagcg aaatagttgg aagtaacgat 738060
tttgttacga gctctacggc tccatgctgt gtccaagcca gtttatgaac atcatcagat 738120
aattgcatcc gtcggataaa atatcttatc tcacctgcta taccattttt ccctctaatt 738180
actttaccat tagaaattat tccttgtccc cctaccccaa atccaaatgg ctgtgaatgg 738240
aaaataatat tatcatactc tggatgttct aaagaaaaac ctacaactgc tgcatttgca 738300
ttattataaa caaaaacatc aattccatat ttatcttcaa aatcagcttt tatatcaata 738360
gttcttccat ctgttggttc tttcaactgc ttttcatctt taacaatacc cggtgtcgca 738420
attccaatca tatcaatgta agaatgtttt aataaaatgg tatcaataat atcgtagaga 738480
tcgtatatat tcattgtagg tttaatgaca aggttactat caattatttc acatttatca 738540
tttaaccgat aataaatacg tgtctgctct ctactaatca aaataacaat tgataagata 738600
cgattttcat attctgcaca atgggtacat tcatgcgctt gctcattact tttttcttgg 738660
cggaaaatct caagctcact ttgaataaac tttaaagcag ctaaagcatc atacgaagca 738720
aataccgatg ttggtatttg taataccggc ttttctgtga tactctcttt taaacgtttg 738780
agcatatacc caatttgtgg tgcaattaaa attacatcat acttttctgc ttcttcataa 738840
atactcatat aagatactgc atcaaaatgg taatctaacc ctaacattcc tgctacagaa 738900
tttaaattat cagcaaacat agaagttgta agtcctgccg aacatgataa taaaacacgc 738960
aaagtttttt cttcttttaa cccaatcaat gtttcaacca tctcatcata taattgcttt 739020
gcatgatttt catcattgag ttcaaaatga agatagaatt taacagaatg atccttattt 739080
gaaacaatac taaattcaac gattgtatat tcctcaatta ctgtaaattg aatcgatgcc 739140
tcaccgtatt cagttactaa tttaataaga tcatcgtttt ctaaacgaat ctcatatgga 739200
gtattatgat gctctcgaat ccaaccttta aaatcaaaaa ctgccttttt ttcagtcatt 739260
ttatccctct tttctcttta taattttatt ttaacatcca taataatgaa catcaaataa 739320
cattatcttt atgaccaaat aaaaagacga tacaatatta attaacttaa ttgtaaagtc 739380
ttttttattc aacatattta cgattgtctt tgccaaaagt aaatggcatc atctatccaa 739440
ccttcagcta ttgttcctgt gcctaagcca aatccatgtg atagaccctt ataacaatga 739500
aactcagttg gaatatttaa tttatttagg tgctctaacc gttttttcat aagaatatga 739560
tctgcaatat aatcgtttgt tccaatacat gcataagttg gagcatcttc atttgaaaca 739620
taatcatacc ctgtatactg cataatgaca gcttcggctg aagggacagc aatttcacta 739680
tatgaagata aaaacttttt atttcccaat actgctgcca ttctagcacc agctgaccca 739740
ccccaaagtg aatagtgtct tttatctatt ttcagcatat tcgcattatt atatataaac 739800
gaaatagcct tagctaaatc ttcatacgga tgctcaacac gataaatcaa agcaaaagca 739860
ttgtacccac gcttacttaa ctctaaagca tgtggaaaac tatcatgcat tgctcctaca 739920
tatacaaaac caccaccagc attgcatatt gcaaaaggcg catctttact tcctttaaaa 739980
aagaacaatc ctacatctct ttttgaagca tcatttaata attcttcttt agaataaatg 740040
ttataaaata ttgaatgatt ttgagcatcg tgattgagtg tatttataat ctcaattgtc 740100
ttattcacat ctatataatt ataccataaa taaattttag acgaacttaa ttctttaatc 740160
gtcatattta gagctatcgg tctattgatt ggaaatagta accttcccca tgttttaaag 740220
gctggaagtt ctaatacttc ttgaatagta gtattagaac ttatattcat ttttaatgtc 740280
cgccgaagac atcaaaatca attgtatcta ataaagcatc aatttctttg atttcatcaa 740340
ttgtaacttc aatttcccct gctctaaaat tttcttctaa acgttctaat tttctgcttc 740400
ccgggatagg cacaataaaa tccttttttc ttagcatcca tgctattgaa agttgagcca 740460
tagtacaatt tttcttttct gataatactt ttaacaaatt caataatttt tttgcttttt 740520
catacccttc tttttgatat tgaggcatat tatttctaaa atcccctttt tcaaaggtag 740580
aatctggtgt aaatttccct gaaagtaatc cattagccat tggagaaaaa gctacataag 740640
ttattcctaa ctctttacaa acaacgaata aatcttcata ccatctagcc atcattgaat 740700
atctattttg aatagctgta actgggcaaa cagcatgtgc tcttcttaaa tattcttctg 740760
ttgtctccga aattccccat gctttaattt tacccgctgc aatcaattcc ttcataactc 740820
cagccactac ttcaggttca actttaggat ctatcctatg ttgataatat aaatcaatat 740880
aatcagtctg taatttcttt aatgatcctt ctatcgatgc atatattttt tctggtgagg 740940
aatctaattc taaatgatcc cctttatgtt caactccaaa tttagttgca ataacaacct 741000
gttctcttac ctcctttaat gcttcaccta caagctcttc attataagaa atagttccat 741060
cagtattctc accagtataa cattcagccg tatcaaaaaa attataaccc attttataag 741120
cctgcttaat agtttgaatt gctctctctt tatcttcagc taagccataa gcatgagaaa 741180
atcccataca gcctaatcct atcggactga catacatatt cgttttccct aactgtcttt 741240
ttatcatcat agcattatcc tttcttattc agtaatcatc ccacgataat tcattccata 741300
taaatttgca aaacgctgca ttgtatattc ccctgcttct aattgttgtt tcgttggagc 741360
ataaccttgg aagataaaat acatgttttt accctttaat aaactttcat caacatgttg 741420
ataaaaccgg tctaatagat tacgaacagc tccagacata ctatgccaat aaagcggtga 741480
gccaattaca attgtatcag ctttactcat cgctaaaaca acttcatcaa attgatcatc 741540
tgtaaaatgc tgaccataac tataaatctt ataatctact aaatgcaatg tctgataatt 741600
tttacccttt agaaattgct cacttaaagc aaccgtatta ccatttttat taggacttcc 741660
gttaataaat aatatactca tttttttcac tcctttaata atctattttt tattcatgga 741720
ttttcctatg aacaaccatc cttacaaaat caggttcaaa gtgtttagcc cgtgaaccac 741780
tatatcccat atctaaggat gaaatttttt tcatctcatc attattcaac tcaaaatcaa 741840
atacattaat attttcaata attctctcta tatgagttga tttagggatt acaacaacat 741900
ctctttgaat attccaccga agtaatactt gacccactgt cttatgatat ttttcagcaa 741960
ttccttttaa catctcatct tcaaaaggat tatatctacc gcctcctaat ggtgcccatg 742020
cttcaggaac aacatcataa tatttcattg tctctattgc ttgctcctga gtaaaatatg 742080
gatgcagttc tatctggtta accattggct taatttctac aatttcacaa aaattcgtta 742140
atatatttgg atagaaatta gaaacaccta tagctcttaa ctttccttta tgatatgcat 742200
cttccatagc ccgccatgca gcaaagtaat ctcccattgc ttgatgaagt aaatataaat 742260
caaaatattc caatccactt tttttcaatg aattttcaat tccctgtttt gctgtttcat 742320
atgttcgcat atcttgcacc cataattttg atgtaataaa cagctcttct ctcgtacaga 742380
ttcccgcttc aatagcttgc ttaacagcat ttcctacagc atcttcattc atataagaag 742440
ctgctgtatc aattaatcga taccccgctt taattgcttg aaatacagtt tcttgacatt 742500
cttttttatc cggtacttga aataccccta aacctaaaat tggcatttct atttgattat 742560
ttaaaataat atattccata atcttatccc ccttattatt cctcaccgtc aacatctgga 742620
attgttgttg ccagtatatg ctgtgatttt tcagttattt gataaaatgg acaatgttta 742680
tttagttttg ctatttcata catttcttca tttgttagta caaaatcaaa taactcgata 742740
ttttctaaaa tgtgattagc acttctactt cccggtactg cactaaaccc catttgcgtg 742800
tgccatttca aaataatttg agacgttgtc ttatgatatt taattgctaa tgctttaaat 742860
aacggttcat ttaacaattc attactacca tgccctaaag gataccatga ttgtagaata 742920
atcccatttt caaaacaaaa atcttttacc ttttcagccg gataataagg atgacattca 742980
atttgcatta ctactggttt aatttcacaa atatccaaaa tttcttgaat ttgttcaacc 743040
ttaaaattag ataaccctag tgctttgatt ttcccctcct tataagcttt ttccatcatt 743100
tgataacccg caatataatt atttaaaggg tgatgcaaca gcatcagatc aatatattca 743160
actcccaacc gttctaatgt ttgctcaaca gcattacttt tttcataaaa cgtcggagct 743220
aattttgtct caataaaaat ttcttttcta tccaatccac ttttactaat acctctacct 743280
acactttttt cattagtata gcgattagct gtatcgatca aacgataccc attttgtaaa 743340
gcaaaagaaa cattatcttc tacttgttta ccaaactgtc caattgttcc aaaaccaatg 743400
atcggcatct tcacaccatt actcaattca attattctca ttaatatttt acctcctagt 743460
atattgtaga ttctgactag ttcactataa agctatctag ctttcatctt gctttaataa 743520
tttatctttt taaaccacag atcatctcaa cagttgctgg atcatagtga gagaaaaatg 743580
aactcgtatc tttattcata tttgtaatag ttttcatatc ttcttcactt aattgaaaat 743640
caaaaatatc aatattttct aacattcttt cttttctcac cgttttagct aatggcacaa 743700
ttcctctttg gactaaccat cttaaaatta cttgacctac tgatttgtta tatttttcac 743760
caatttccat taatgtttca ttagtgaaga ttcccttctt tccctctgca aacggtgccc 743820
atgcttctaa ttgaacacca tatttttgat tatattctaa tgcttgattc tgttgatgaa 743880
atagatttac ttccacctga ttcactgcag gaacaacatc tgtatctaaa cataaatcta 743940
ctaaacggtc cggataaaaa ttagatacac caaccgcttt aatttttcct tctttgtata 744000
aatcaactaa agcccgataa gcaccatgat aatctttaaa aggctgatgc aataatacta 744060
ggtcaatata atcgagtttc atcttttcta aagattcctc caccgatgcc ttagcttttt 744120
catagccata gtttgtaatc cagacttttg ttgtaacaaa caactcttct cgaggtacat 744180
tagtttttaa gattgcttct cctacagctt cttcattacc ataagactgt gctgtatcaa 744240
ttaaacgata cccagtttca attgcctcca ggacaaccct tacacattct tctttatcct 744300
tgatttggaa aactccaaat cctgccatgg gcatttttac accattattt aaagttatat 744360
attccattat ttttccccct attctagcca tatattttta gtctcaataa tcttgtttta 744420
ataatttgat ttttaaattc aagattcaat cataatcttt tacatttaaa tatatttagt 744480
ttatatacta aaaatcttta tctgattaac agtgcactat aaattatgca cttgtatcga 744540
taagaataaa aagttaaata tggtttttta aataattaaa atttccatct caccttattt 744600
atctttaaac atagtataaa tcttagagtt aactataagt caataaaaac ttaatgttat 744660
taatttaaaa tatcactaaa taaaaaaaga ggtctctttc aaacctccta tccaatcata 744720
aaactatttt taataaacaa atctataacc caactataaa atatattact cgactgcaca 744780
tatacattta tttttattag tatttttagc tttatataag gcttgatccg cctgctctaa 744840
aactgcttgc caactttctt ctccatttaa aacacctatt gccccaccaa tacttacagt 744900
taaatattca cgacttgaag tatttggcat taataaatgc agacgttcaa cagtatgaca 744960
aagttctgta ccaattcttt gcatttcttc taaatctgta ttttttaata aataaacaaa 745020
ttcttctcca ccataacgaa tcaaaaaccc ttcactcaaa cataaattta aagcattaga 745080
aactctcttt agacattcat cacctttaat gtgcccaaaa gtatcattat aagatttaaa 745140
atcatcgata tcaattataa aaacacctgt tttaagctga ctatcgcgac tctctaaata 745200
aatattattt aaacaattag ctaaataacg tcgattttga agccccgtta aagaatcatg 745260
atgggcaata aaatctaatt ccgcactttt ttcttcaatc atcctatttt tttctagaat 745320
gatactctga tttaaaaaag tttgtcgcat tgattgataa tgataatatc caacaaatag 745380
agccataatc gttaaccagg tactattaac ataaatacta taatgactcc ccaatggttc 745440
accatgtttc actaattcaa ttccagtaat caaaataata tcagagaaca aatacagagg 745500
aacaaataat tttggcggta aataaacaag aatagcaata ctcaacattg taataatatg 745560
cacactaatg ttattagaaa cacgattatc atatatcgtt actgctagcg accacatgat 745620
taaaaaaaca atatagtaat tttgaacttt caacaataaa ccctttttaa cattcttttt 745680
atgcaataaa atcaacccta agacacagat gataaacatg agtgtgtata aaagcatata 745740
aatcttactt gacttggtat aataggtaaa atccgtatat acacttacat agaccatatt 745800
atagatttga aataacataa taaaaaatat cgggatccta aaatacttct taatatcatc 745860
ttcgagaaca tcaataaatt caagttcttg ctgtttagtt agctttatct tttcagttaa 745920
tgacaacaac ttcataattt gtcctttcta aatatctatt tataattctt attgacgatg 745980
taagaacaaa attggaaatg gattcccttg ttcatctaat tcacttcgcc gataaatagt 746040
aaaccccata tattcataaa aagctagagc ttgaggattt tgctcattta cacagacttc 746100
agtgatctca taatcattta ttcctatctc taataaattc ctaccaatac cttgtcctcg 746160
acgttgtgct gtaataaata acatctctaa tttatcctca gcaatcccca taaaagccaa 746220
tgtttcttta ttatcaacag caactactaa aattggaatt tcttcaattg cttgaaaaac 746280
atactttttt atttctcgaa tattagtttc actaaaaaaa tcatgagttg ctctaatcga 746340
actttcccaa accgtaacaa gtgaactaat taactgttcg tctcgttcaa atactctttt 746400
tatttccatt agctcctcct ttattactca aagaaatcct ttaaataaat atactgcatt 746460
ataaattttt taaacatcca tagcaactac acgtttaata tattttttca taatcttttc 746520
aattccaaca tttgttaaaa tgatttatca ttatttcttt caatatataa atagttatta 746580
tttactttat tttactataa tcacgtaaaa aagatagtta tttaattaat aactatcttt 746640
ttttcattaa gttatcattt gtattttttg atttacctct tattaatata agtgcaataa 746700
tatttgcagt caacatcgta attacatata ttgtaagaat tgtaaacatt gacggtacta 746760
catccaataa tgctgaccaa tcttcatgct ttacccaatt acttactaat tgataccctg 746820
ctaaaagagt aagcacggta aaaacaagtc ctaaaatcga aaaccaataa gccctcagct 746880
tctcttgact tttaaatata gacagacagc tcatcaaagt acagataata ctcaagcttc 746940
caaagataat ccacatacta cattattctc ctagatataa aatttaagat tattttaaat 747000
aagctcttga tcaataaact ctatataatt tttcttaaca acttcatctg gatgatcaag 747060
gtaccactga tatgattcct ctaatccttc gaaaagactt ttttgacttg gcaacagctg 747120
attttgctta gttacatcaa gaacataatt atagttatga aaactaaaat aatcacgttg 747180
attatcatgc ttagttacat atactttatt tagcggtact cctacaactt gataacataa 747240
ctcaacaaat ttatttatat caacaatttc gctatttcca acattcatga tatgatcatg 747300
agggtgcttt ttaataatgg tttccattaa cttgcataga tcttcaacat gaaaaaactg 747360
taataacatt ttaccatcat taggtagata gaaagaacgt ttctttaatg cacattcaaa 747420
cacaaaaggt tcgcgataaa cattttgcat tggtccatat aaatatggtg gccttaaaat 747480
atatgcttga ggaatatgac ttagtaaata gttttcagct tcaattttat tacttccata 747540
atctccccag atagaatttc ttccaacctt ctgctcctct ttgaacggtt gtgataaact 747600
ttccggataa acagcactgg aactaatcaa aatataatct ttgaccccat ttagaccttc 747660
taacaaatct ttgacatctt gtttagtata agcagtaaca tcaaaaacca catcaaaatc 747720
atatcccttt aacaaatttc ccaaatgatg tcgatcacct ttaattaatt ttactccttc 747780
aatctgtttt cgatttccac gattcaaaac ataaacatca taatcatgat ttttaaaata 747840
agttgcaaca aatttactta caaaaactgt tcctccagtt accaaaatct tttttgtcat 747900
attctctcct tactttataa tgatttagca catgcaatta aataatgacg agcattagca 747960
gatgtcactt gtttagcccg catcaataag gcttgttttt tcagttctat aatttgtaat 748020
gaattatctt gcaccatcaa taactcaatt aattgcaatg ccatttgata atcttcttgt 748080
gccatataat ttttaatagc taatattagt ttatcattat caccaattaa agcaagtacc 748140
gcctgattat aagcctcagt tggatgtggc aataacttca caggatcccc atcaaaccat 748200
cctacataac cattataaat acttttcact gaccattcta cagtaccata atactcacct 748260
aaatattctt tatcctgata tattggtgct aatttaacat ttttaacagt ttcttccaaa 748320
gacattccct gattcataca atctaatgtt ttaaataaaa tatcctcgat ggcatcccta 748380
aaagttccca ctattgcttt aatctcattt tgccataaaa ctcgtgtatg tcctggtaat 748440
aatgcaacag ctggataatt taaaatctca tttaaagtat caatccatgt cgcaacatcg 748500
cgatacatgg ttcctcttat tgcataaaga ttaggccagc atccataata attatctcca 748560
caacacatta tctgatcatc ttctaaccaa acatagattt catcatctgc ttcacctaca 748620
gcactaacca tctttaattt aattccatca attactcgtt caaccacttt ttgctcataa 748680
tatgtcgtcg gttttataaa atcatatttt ccttctttaa tttcttttcc ttcacggatt 748740
ccaattcctt gactaatcgc ttcctgatct gttaatccat aaccatgctg ataaatccct 748800
cgttgattta gtagtttact aattctatcg tagtatttta aaattggttt tcgaggttta 748860
aatgctatta cttctacaac tgtatcccga aaagtacctg ctcctcctaa atgatcagga 748920
tgtccatgag tataaataat tgttttaacc ggtttatcac taattttcgc tagttcatct 748980
ttcatcactt ttgcacgata atcagaatca agagtatcaa ttaatataat tgaagtttcc 749040
ccaataatcg caattgcatt actatgtcca tagcccaaaa aatgatatac ccgttcatta 749100
actttagtaa ttttcttttg atagtttgtt ttcgtaaaat taattaactt ttcttcacct 749160
aacattgctt attcctcctt atatatcatt atattgatta tctagtcttt taatagtagg 749220
cacctttagg taactgtcaa aaccgtagtc atttggacta cggttttatt taatcatcta 749280
aaataaatga ctttacttga ttctttttta gtttattatt agtcttaact atctcttctt 749340
ttaaatcaac aaaatcttta agatcatgat ttaaagaaat taaaacctct ttattattag 749400
tattaaaagt tcgataaatt aatttatttg aagattctgc cttttttaaa acacttagtg 749460
tagtaagttc attattttca tgaagcagag agaaagtata tggagtgtta aaatcaacct 749520
catttaactt catcgcattg tacggcattt tattataact aattaatggc gttaaataat 749580
ctttagctaa acgtgataat ttagcgtgat cattttcaat aacaagcgca aatctaaact 749640
ctaatggttt taataattgt gaatctggtg taggcatctt aattcctgat ggtcgtcccg 749700
gacgccgaac taattcttct ttacctaaat agccaactga tcgaaataac gtaattgcca 749760
gggtattata attatcccca attacttcat attctctaac tgaattagtg agtaaagcta 749820
atggacaacc cttgattgca acgtaactaa gcattggata aatactatct ggccgctcgc 749880
tccaattatc ttcttgccat gattctatcg ccatatcttt tactgggcgt tcaattatcc 749940
caaactgatt atcactaact gaggcctgag cccaaatatc agttggaaga agtactctaa 750000
gtcgatgatc tttagctgta ttatcaatat tagttgtaat gtcaagattt cgttcccctt 750060
gttttaattc tatttgaaat tcaattttta aacttgtatc acatttcttt tgtttacgac 750120
ttgttaaatc ttttggtact ttcatttcga caattatatg agctgtagta gaatacctgg 750180
atctattgat ttgataatct gccttagcat ctttagaagt tatgatataa tcttccaata 750240
atggtgaata atcataacca tcaccctcat cactaccatc ttcaatcaat aaaacggaat 750300
cataagtatg atcattaact aaatcatata tttttaaagt tccattacta ttaattttaa 750360
tctgatagta ttcattttcc agaaagtcca ctttatctaa taaaatttct tttggctcta 750420
ctgcttcttg aattaaataa gcctgatacc ccatcgcagg aaaattatct ttaaattcaa 750480
ttgtatattt tataaatgga tcataattcc cataatgaac aatctgacga tcaattaacc 750540
cagcatcaat gatttcttta ttaataactt gataatctat ttcatgaccc tcactagtaa 750600
caattttaaa acttttcatt ctcgtgataa cttcactgcg aaccactcga tttcttggat 750660
aagggagtaa attaaagacc gttagtttat caagcgcaat atctttaggc attgcatcag 750720
taatctttcg tttataaaag tcaatcattc gctctacttt ctcattagca atcgtaaaac 750780
ggctgcttat ttcttgatgt actttatcac tacaacaaca tccaattgaa tcatgggcat 750840
gatttttcat tatctctttc catatcgatt ccatcatccc atcaaaatac tcaaacccta 750900
atttaaaagc aatggaagcc aatggctcta gcagattggt aattttattt tcaattacgg 750960
tattcattgt tttgatatct gcccgtgatg aaaaaatcga acgatgtaca cgcatatatt 751020
taccatccag cagttcacca tgaaggatat catagttatc ttttttctct aattctttaa 751080
atatctgatc atagttactt aaaaagaagt ttttatctgg ataaagtctt tttaactgct 751140
caatgacatc aaatatattt ttttgtaatg gcatttggtc gtgaccatta ggaattaata 751200
tatgttcact agttgctcct ttttgtaaca ctggcatata tttatcacaa cgttttttta 751260
attcatcaag atctgtgggt aaatattttc caattgcata accaagtggt aatagttgag 751320
ttaagacttt tgaaccatcg tcactagtcc aataaaactc tgtcttattt gaacccattc 751380
gctcactcgt tccccgccag aatatgcttc ttgtaattcc aaaaccgttt aaaatcattg 751440
gcatttggcc tgactgacca aatgaatctg gtaaataacc aatattcata ggttctccaa 751500
aagtctgact atctttatga ccgtataata aattacgaac aatcgactct ccacctacaa 751560
ccatctcatc agtttgagtg taccaaggcc caataattaa tttacctttt ttcactaaat 751620
taactattcg tgataaattt tttggtttta atgctagata atcctcaagt acagctgttt 751680
gtccatcgag aacataataa ggataatcct cattattttc taacatttct aatatttctt 751740
ccatattgtt tagtaataat aactttgatt cttcggctga aaaataccac tcacgatccc 751800
aatgcatatg ggggacaatg tgtacttgat ttgccatgct attcctccta ttttgcctta 751860
gctaatttct gttttcgagt aattacaagt agcaccgctg aaataatcgc tccaattact 751920
gccgctccaa accagacgat catcgctaat ggaatattat cagcagttaa tacgaaaata 751980
gagaatattc ctgccccagg tacatcaaga ccaatattaa acatcgctac aatcgctcca 752040
caaactgcag aaccagtaca tagggatata attacacgaa ttggatctgc catcataaac 752100
ggaattgccc cttctgtgat tcctgctaaa cctaatagcc aggttgaatt tcctacttca 752160
cgttcttctg gtgtaaataa atcttttcta aactttgtcg caaatgtcac cccaaatgca 752220
ctaaccattt taattgaagc aaaagcacaa tatggcatta aaactccttc cgccattgca 752280
gcaacacaga aagcatatgc agctttattt actggtccac ctaaatcaaa agaaaccatg 752340
attcctaaaa cagcccctag taaagcagca tttgttcctg ccattgatcc taaaaagtca 752400
actaatgctg tattgatcat tgcaactggt ttacctaata cgactaacaa taagactcca 752460
acaatcaaac aagacaatac aggataaatt acaaaactca caaaaccggc aaatgttcct 752520
ttagctggaa tccatttctt taaatagcgt attgaatacc cagcaatgat cccaccaagc 752580
atcccgagta agaatccacc gccaacggta ttagcacaaa atccagccgc aaaccctgaa 752640
gctaaagctg gtttatcccc gattgaataa gccatataag ctgataatac cggtaccatc 752700
aaggttccta acaatccact tcccattgat ttgatcaaat aaagccaact tccttcggta 752760
ttcatcaaat ctgtaaaacc aaaggttctt gcaaagatta cacaaattgc tgcaatcatt 752820
ccgccagcca cgatcaatgg aataacatga ctaattcctg tcataaccgc ttccttaact 752880
gtttctaaaa atccggcttc ttgatgtcgt gaatgttcta catactcacc acgagcagtt 752940
tgttctgctt taactaacgc tgtttcgata atctttttag catcctttaa tggtgcagat 753000
acttttgttt taatcgttgg taaatgacta aaacgttcct cctctttaac cgctacatcg 753060
acagcaaaaa tagctgcact tgcatttttt aacatctcat tagtatgacg atcttcaatt 753120
ccattagccc cctgcttttc tacatataca tttactccca actcttgccc agcttttgtt 753180
aatgcttctg ctgccatgta agtatgggca ataccagcgg cacacgcagt aaccgcaacg 753240
attgagcgat caaaggattt tatttcatca ctattaaccc cattatccag attttgataa 753300
aattctttta ctgttttaga agcatataat ttttctgtat atgtatgatt agccatcttc 753360
gtcatcattt ctgctaataa ttgcatttga accgaattct tatcattttg gggaattgca 753420
agtaaaaaaa catattgtac tttgttacct tcaacaacac tttcccaatc cttcacaggt 753480
ttctttaaag ttacaaccgc aaaagctgct tctctaacta ctccatcttt tccatgagga 753540
atggccagac cattatcaat ccctgttggt gttaagcttt cacgttctaa tactgcttga 753600
taaaaatctt cctcattact aatttttcct gcctgatata atttagaaac taagaattta 753660
attatttcat cttttgatga caaatcacta tttaaagtaa taagctgctc acttgttaat 753720
ttagataatt ccatttcttc tgccctcttc ttttaatttt attaatcact gacatgtctt 753780
tccctgatta caaaaatatc atagcatatt attttgtaac ccttttcaat ttggaaaatc 753840
atacacttat ttttaaataa aaaatggatg taccgtgtat ttatacacag tacatcctcc 753900
aaaatacctc tgtcaactct cgaagcagca tcatcatccc tgttcgatcc gcaacattat 753960
agccattcaa tttttgttca tcaccccaat aatataatgg aatatgtgct aaaccagcca 754020
atcgattttc attaaaatgg gtaaccgaaa taacaaaaat tccattctgt tttgcttctt 754080
ctacccaatt attcaaacga ccattctcac cacttgcact aattacaaac aaaatatctt 754140
tttcttcaca atgcttgatt cgatattcaa tttcacgata agtttgataa tattcagctc 754200
gataatcata acatcgcaaa ttatcgacca tcatttcaca aaaatataat gactcaccga 754260
caccaataaa gtgacatgtt cgggcattct tgatcttagc ggcaacttct tctaacgttt 754320
tataattaat tagttccatt gatttataca aattctttga taataatttt tgaatatcta 754380
aattttctga tacttcgtta ttaactaaaa atttcatctc tgcaaagcct ttatacccta 754440
actttttaca aagacgcatg attgagttgg gaacaagata aagatcttcg gctacctttt 754500
gaattgataa atgttccaaa tttgctttat ttttacgaat ataatcaaca attagatcat 754560
ctgtatcgtt tagtgtaaac tcttgttgta agacccgttc ttcaaatttc attatattat 754620
cctccatgac aagataaata tcaactctct caatataact tatattctaa cattattttt 754680
tgatttcggt gcataatctt tcaattctgg aattgctccc gcagcaactg cccataaata 754740
caaactggca attgttgcat atggtccata gcgacgttta tatttagtga atagttgagg 754800
tgtaattcgc cgatgatgat agaccatgcg cattccccgt aaaattgcta aatcgctata 754860
actaattata tctttacgtt gtaatgaaaa tgttaaaatc atctctgctg tccatctccc 754920
gattccaggt aactcacaaa gctgttctat aacctcttca tttgatagat cagctaatcg 754980
ctccaaatcc aattgatcac taatgatccg tctcgttatt tctttgatat aatgtgcttt 755040
tttcatcgta atgccacatt tttgtaattc ctcagctgaa agtgatttaa aatttgctgg 755100
ggtaatcgga ctaaaagaat tgttgattct ctgccaaatt gtttgatggg ctttagtaga 755160
aatttgttga ccaacaatcg aattaattaa agctgcaaat aaatcaggta ttaccgcacg 755220
tttaattata ccaatctgct cgattacttg ttttaaaaca ggatccctac ttttcaaata 755280
ttcaatttca atatcgctat attcaaaata ttccattata tactccaacc tataatctta 755340
tcgcatagtt acaataccat cattttaaaa caatcaaata acttttttga ctatattgat 755400
tagctttatt aatttcaagt atacttgaag tactaaactt tgtaaataaa tgaaatatta 755460
tataaatcaa gtatgtttcc ttatgtaatc aaatagttta tattactgct tttatcctta 755520
tgattataaa ttgttagttc ataattatct aataaagcac aacgataaaa atactctagt 755580
aagtttttac tggagtattt catttatact ttaaataact caataatgtc attagtagac 755640
attgttgtta tactaccttc attattttcc acaaaactat cagctaagtt tttcttttta 755700
ttttgcagtt ctaagatctt ttcttcaaca ctatccttca ttaccaattt ataaaccgtt 755760
acaacatttt cttgcccgat tcgataagca cgatcagtcg cctgattttg tgctgacata 755820
ttccaccaag gatcaaaatg aataactgct tcagcagcag tcaaattcaa tcctgttccc 755880
ccagctttta atgaaatcaa aaatactgtt gtatcatcat tttgaaattg attaactaat 755940
cgatgacgtt cttctttttt tgtatcacct gttaattgat aataagtaat actttctttc 756000
tccaattctt tagcaattaa atcaagcacg gaagtaaaag aagaaaataa tagcactttt 756060
tgattatttc ccaggaaatt tcggattaaa tcaagacatc ccgataattt tgatgaaata 756120
ttcgaaatat tatcatatat tatccgtggt tcacaacaaa tttgtcttaa tcttgtcaac 756180
attgctaaaa tagcaatacg atctacatta tcataattaa gctgttcttg cagttcttta 756240
ttgacctgaa ttaaattagc taaatacaac ttattttctt cttcattaaa ttcaattgat 756300
aatgtttttt caatcttctc cggtaattca gtcaatacat cttttttatt acgtcttaag 756360
ataaatggtg taattaattt ttttagttcc tgctgtttgt tttcatcatg atttttaaca 756420
atcggtgttt cataattagt tttgaaataa tgatagctat acaaatactc tggcattaaa 756480
aaatcaaaaa ttgaccataa ctccgccaaa gaattttcta taggagttcc ggttaaagca 756540
aaacgatgtt tagcttttaa cgattttact gttatcgcat tcttagtttt aggattttta 756600
atatattgcg cttcatccaa aataatattt tcaaattgat aaccatcata aagattagca 756660
tcacgacgca tataatcata agtagtaatt agcacatcaa cctcattaaa ttttctaatt 756720
gcttcttttc gtcgttttag actgccgtga atacaagtac aagataaaga attagaaaat 756780
ttatgtatct catcttgcca attcaatagc aatgatgatg gacaaacaac taaactagtt 756840
tttttatcat cccgattttg atccagtaaa acaatcattt gtaaggtttt accaagcccc 756900
atatcatcgg ccaaaattcc tccaaagcca taagaactaa ttgattgaag ccattgatat 756960
ccaaatttct gataatcgcg taaaatttct tgataattag gcgttaaggg ataactctgt 757020
ttagctatat ctttaaaatt atcaataatt tctttaaata cggtactacg atcatatact 757080
aaataattgc ttgtttcggc tttattatca agactaaaag cccgatagac atccatttct 757140
aaatgtccat cctcaagcat ctttggtcta atttgataat cagtcataaa ttcatttaat 757200
tcttccagct catcagaatc aagatataat agttgaccat tttttaaccg atgaaatttc 757260
ttcttctttt gatatgagtt taagactaac gctaattcat ctttaggaat atcaatactt 757320
tcaatgtcaa ttgccaataa gtcattttct aaagtcactc ctacattaat actaaattga 757380
cttttcttcc caatcttttt aagtgcatca ctaaccatca cttcacaata attagctaaa 757440
aaaggcaaac cttcatttaa aaaggagtaa gttttttcac tttctaaatt caaatacata 757500
caatgttttt caaaatcaac tacatcacca atctctttta aataatcttc aattaaatca 757560
aaattaattg atgtttgctt tctcgactgt tgaaatgaat aaatcgtttc taggccttgt 757620
ttactttcaa gataaacttt gatttgttcc aattcattaa tatcgccata gagtgtcaat 757680
atttctgttt cgacaacttc acttgttaat aagtccccag tataattaaa atattgctta 757740
atatcattta aaatatattt aacaaagtca tttacatctt cttttgctaa taataatttg 757800
tctttacttt cgcaattatg aataaatttg attgcttttc cttcatcatc cagcttaacc 757860
atacctattt cattttcagt aatcttataa agatttttat aaccacaaaa ttcatcaaaa 757920
tcctttaatt caagcgaata atatttttca agtttcctta tatgtaaagt aggctgataa 757980
ttgtattgat aaattgataa atgttgatta gttttttcta aatcttttaa tacttcatag 758040
atatattcaa tactttcggg aataatcttt atctcatttg tcacatgcga tatatcgtaa 758100
taatattcct gttgataccg ctcataagtg atcatacaaa atttcattaa ttcaataatc 758160
ttcagtgctt catcactaaa tactttttga ttatgaacaa acgctaattg tttaccatat 758220
tcaacatatt cattatttgc taatgcactt aaaaaattag gaatattttt tattatatac 758280
tttttatcac ttcctacttt gaattttaaa catgggtgcc cataattaat cttgatctgg 758340
acttcaagat catacttttg atttagttta acctgattaa aatcaattgc tttagcagtc 758400
ttaaatgatg ctattaggtt ttttgttact gctaattcat tttttagcag ttcttcttcc 758460
tgctgctgac gaatttgtac taacttgtcg aaataactta tcttaccatt tttactttta 758520
tatttaaatg gaaaatcatc aggtgataac tcttgaacct tcagcaaaac agccccaata 758580
tgaccgcaag ccgagagttc atcacaccaa taacaattac aactatagtc agtaatctta 758640
ttatcttgat caataacgat tttacacaca ttttcataac taccattatc aacaatgcct 758700
tcaattgtat aatcatcaaa aagtcgatca taagtaattg tgatttctct aacataatct 758760
ttttgataat atattcgtcc tgttcttaga tttctaacac tgcttacgat tctatgtaat 758820
tctttgtcag ttacaagcac ttaccagtca cctcctaatt ttctttaaaa ttatagcata 758880
tatcgaataa tattcattaa tattacgact ctaaccatta tgactaaact aaatacatag 758940
agttataaag atgtaatctt gcagcaagta tttatttcaa taaatttctt attactgcca 759000
taatcaaatt tttaaataat taaatactca tttccacaag cattaataaa caataacaaa 759060
tcatcatagg taattgatat tgttgctgta ttaatattag ggtgaattaa taatcgttgt 759120
gctcttaatt cacgatcaat caatattttt actcgcttat tatcattaat tattcctaat 759180
ggtgtcactg atcctggaat tagctttaac aattctacaa gttcttcatc actagcaaag 759240
cttagccgct tactaccaat ttgtttagct atatatttca agtcagcacg cctttcaacc 759300
gtcatcatat aaatgaagaa ttgtttatca ctacttttta aaaatagatt tttacatgct 759360
actccatcaa tttgctcatt aataaacatt gcttcttcaa cagtgctaac tgattggtga 759420
ttaatttttt gataatcaat acctaactgt gttaaaaatt tatatatatc cattgttaac 759480
tcctcttttt atgataatga ttttaacata ttaaaagttt aattgaaaat aataaaagca 759540
tccaaaggat gcttaatcaa ttttctttaa ttcataatca aaaccatatt ttaaaatata 759600
ttcttctaga gtccaattat tatcataaat tattttagct gctttcttac caacataacg 759660
taaatgccat ggctcattag cagttccagt aatatccgaa cgatttttag gataacgaag 759720
aataaagcca tatttataag catttttagc aacccattta tactcatccg tatcaccaaa 759780
aaccattctc tttttatcaa ttacactttg gctagttaaa tctactccta accctaattg 759840
atgttcactt gagccaggtt tcgcaactaa accactagca gtgacttcat cataacggtt 759900
aaaataatca ttataaattt ctacttgttc atcatatgag cgatatccac tatttaaaac 759960
taaatgataa tcttctttta aagcatcttt attcatatct tctaatgctt tagctgcatc 760020
ttttcgaagt ttattatggt tattatcagg agcaattggt atatcaggta caacaagatc 760080
agcagggaca taatctttag gtaacacaaa acccttttta atcaacagaa gtgtattact 760140
aggatctaaa acttcatatt ctgatccaac agcattatta gcatcaataa atgggtaagt 760200
aaccgtaagt acagctgtta ttggctcttg attacttgca agatacttag gcagatcctc 760260
aaagaccatt ccattaatct ttaaataaga tttaatttgc gaatatgtat atttattatc 760320
gacgattacc ttaaaatcag acagctctgc aactttcatt aaagataata cttgtttata 760380
actatatttt aaatccttga gatcttgata ataatcctga tagaaagtat caatatattt 760440
tattacttct ttttttgaat aatcttgatg ttctttttga tatgtctgat actctaaata 760500
atgtttttta tttttatatt cattccagga acttaaatca ctgacctttt ccgcatccaa 760560
ataacgctca atctcattat catttagctg taaaataatg ctttgttcag accaaccata 760620
gcccttcgtc attaaccgaa ttcttgtaaa attaaatgca atcaatgtcc caagtattaa 760680
catagcgatt aatacactaa tgattacttt ataagggatt tttttctttt cattgtacga 760740
catgtaactg cttcttttca acctattatc ctcctcgata tattcttggc agtcgacttc 760800
ctaaacgact caaaatctca ttactaattg tattagcttc aagtgcaatt tcttctaccc 760860
taatttcttc tgtaccatct tgaccaatta cggtgactag atcattatca ctgatatcac 760920
taatctcgct aacatctaca agcatttgat ccatacaaat tcttccaact attggacact 760980
tttgaccttt gatcaaaaca cttccatttg aagaaagtat acgtggcaat ccatcaccat 761040
agccaattgg aataacggca attacactat cacgattaac cttataagtc aagccataac 761100
caagactcgc gcctttagtc aaataatgca gcattgcaat ttgtgcttta attgttaaag 761160
ctggttttaa atctaattgt acttttgaat aatcattgaa cgttgagtac actccataca 761220
ttaaaatccc aacccgagca taatcggcat tgatttcagg ataatttact aatccataac 761280
tactttgaag atgaaccttt cctatatcat aatgtcttaa ttttaattca ttaattaaat 761340
cataaaaagc agctatttgt ttttgggtgt attcttgatc aactttcctt ttactatcac 761400
aaacacaaag atgtgtaaaa taaccctgaa tatgaataaa ctggtaatca tatatttctt 761460
taatactctc ataatcgctt aaatcaaaac ctaaacgatg cattccagta tcaatcttaa 761520
tatgaacatt gatcatatgc ccactttcat ttaattgccg agcatgctca cgatttacaa 761580
tggtttgaat caaacgataa ttatgtaatt caattgcacg aatgggatga ctataaccaa 761640
gtactaaaat ttcgccatat atcccatgtt ctcgaagttt gataccttca tcgatagtag 761700
caactgcaaa agcttcaatt cccatttttt gacaatgttt cgcaacttct actaacccat 761760
gaccatatcc ttctgcttta acaactacca ttaatgaact atttttattt aataatgaac 761820
tcaattcatc aagattatgc gtgattgcat ctagatcaac ttcgatccaa ctgcgacttg 761880
tgcgaatatt caccatactt ctcttttcct ttcaataaaa tctctgaaaa taaaacagtt 761940
attatcaata cactaataaa ctgaatcagc gggtcaacaa ctaaatgatc acacttcaat 762000
aatttaccta ttccacgaac aacaacaatc atcaagggat gaaaaagata aatagctaac 762060
gatagatctt tacatttaga tattcgtttg cctgatattc gtaaaagtcc ctgatatagc 762120
caaaacatta ctaccggcaa taagatattc attgaatcat gacgtacaaa aacataatct 762180
gctgcatctt gataaccttt caacagtgat atttctataa acatcaaact tattgctaat 762240
atcgtgctaa taacgattac tcttaaacta aagttaaatt gctttaccgc aagaagtttt 762300
ccaatccaaa tgaataacgg tgcaaagaaa ataccatttc gtgtataatc acttattaaa 762360
aaaatcaagt cataccccca tttacaatat gggtgtatca aaccataata cgaatcacca 762420
cctaatccaa ttaaataaag tagtaccaca attgaaaaac tcgttaataa agatacccgt 762480
ttatctaata ctgcaacagt gatcaatcct agaactgttg ctggtaaata ccacaaatga 762540
tagaaagttc catcgaacaa aacatcttta attatttcat aaatcagatt actttgatta 762600
aaataatgat tataaagatt taatggtaaa taaataatta ttgctgctaa ataaatcaat 762660
agtgtctgtt taataatctt atatagtcgt tttttactgg gattaagaaa atagaaataa 762720
gcagttgtga taaaaaagaa tggtactgca atacgtccta atccacgagt taaataaaaa 762780
tctaaagttg ggctaattgt atctaatggt gaagtatgaa tcgtgacaac taaaattgca 762840
gcaattatcc taaaacagtc gattaaggga taacctttta ctttagacat atggcctcca 762900
tgatgtaata ataaaaccat cacaattatt tcccgatatt tgataactac catgatcact 762960
taagtttaac ttagtctgtt cattaactgc tggaacataa aatacttcaa ctaactttcc 763020
ttggcagtct aaaacatatg gattgaaaat agaatgattt tttatatata aatgatattc 763080
ttcaaaacac cactgatttt cttccataat ttttgcatga acaatcccaa catagcgaaa 763140
atgccatggt tcctcactaa ttttggtaaa atcaatttta tttttagaat atctctgaat 763200
aaagccataa tcacttgcaa tatcacgaaa ttgttgacag atttcctgac ttgtaaaatc 763260
aggacaaaag atatcaattg tttcattttt tactgctaaa tcaatggcta gacctgtttg 763320
atgctcacta cagttcactc tagcaacaaa cttatcaaca aactcttttc catgattttg 763380
aatagcctga ttatagatca tagcttgttc ttgaccgctt cttaaaccac tgactaaaac 763440
aatcttatct tctgctttaa tttcctgtaa tgcttttgtt agcatctcca tagccgtttt 763500
ttctaatgat attgttgaat ccttggcagt cgaacagtta gtaatttgat agttatttgc 763560
aattggataa ttatgattaa ccaatactaa tggaccttgg taaatatcat ctttatttaa 763620
agttaccatc tgcatactta agccctatcg caacaatttt atctattaat tcactaaatt 763680
caaaacctac tcctttcatc atctggggaa aacggctatg atcagtaaaa ccaggaatcg 763740
tattaacctc attaaaaact atttcattgt ttggcgttaa aaacatgtct accctagcaa 763800
aattctgaca agctaatgtc tgataaataa tttttgcagt ttcttgaatt ttccttgccg 763860
ttacttcatc aattctagcg ggcatatgaa ttgttgaagt tttcaaagta tacttttcat 763920
cataatcaaa aaaacctccc gataattcta tttcatctac ctcaccaaca gtcaattcat 763980
cgttgccaat aatcgcacaa cctacctcaa acccttcaac agcttcctct acaattactt 764040
cattatcgta attaaaggca tattcaagtg cttttgttaa ttcttccatt ttgacaactt 764100
tactaattcc atatgatgat ccagctttta atggtttaac aaataatgga aaattcaatg 764160
ctttaacatt aaaatcattt atattatgta caagcacaga cctagtaacc tttatccctg 764220
ctgctttgac taactggtga gctcgatatt tatccataca taatgctgat gctaataatc 764280
cgcagccaag tactggtatt tttgcaagct ccattaatcc ttgaacagta ccatcctcac 764340
cattttttcc atgcaagacc ggtaaaaccg catcaatttg ctgatagatt attttattat 764400
caactatttc catcactgct tgtctttctg gttctaaaca taccgtcact ggattaagca 764460
gttcttgatt ccaagtatca ttactaattt tttcaatttc cccatcataa tgaaaccact 764520
gtcctgctct cgtaatcccg attaaataaa gatcatattt ttcttgcgga aaattcttta 764580
taatcgcagc tgctgattgt agcgacactt catattcact tgattttcct ccaaataaaa 764640
tagctattgt ttttcttttc atattatatc cttccttact actccttcga taaatctata 764700
atataaaaaa aacgctcttc attttttaat ttcttcataa gaaaaaatca caaaattccc 764760
acttatttct tacatttttc ttacaaaaaa atcagcattc tgctgacttt actgttaaat 764820
attaaaatgc tttttaaaac tttgagcaat cccatcatta tcaacactat cagttatttc 764880
acttgctaca ctttttaatt taggaatagc attccccata gcaataccat gtttaaccaa 764940
ttgtaacatc tctacatcgt tgataccgtc accaaaagca tacgtgtttt cataatcaat 765000
tcctaatttt tgatataaat attcacaagc agttccctta gtgaaccctt tgcaataaac 765060
atccattcga atcaaacctg tatcatacgg aatcatcgta aattcatctt ctaattcatg 765120
ataagctgcc cacaactgtg ctgcactatc aaataaaaca caacagctta ccgctttaac 765180
atcactagtt ttaaatacct cattaacatc agttggtctt tcagttgttc cctgaaacat 765240
agcacgatgt tttataacca attcatcatc aagaaaactg caccatgcac caccgcgacc 765300
attaaacatt gaacgaccat tatattttgc atatacatct aattgcttct gcaccattcc 765360
attatcaaat tgttcatcaa tcaaaatctc attattaaaa cgaatataat gtccatcatt 765420
acaaatatac ccatcaaatt caatgtttgc cacactttca ggtacttcac cccgagctgt 765480
tgcaatgacg atcttattac cttgattttt aaattcattt aaaaccctta ttgtctcatc 765540
agttggatgt aacatcccat taggtacatt aactaatgtc ccatcaatat caaaaaacgc 765600
tattttcgta ttcataatgc tcctccttct tttaagtata aagaaattca tatcttttat 765660
gagatatttt aatattatga aaataattac tgaatcacat aatcttttgc atgatcactg 765720
taataaagag cattgtttgt atcaataaac acggcttcta tccccgctaa ttgatttact 765780
aatgctaacc cctgctcttt acctaaagta aaacatactg tgcttaatgc atcaccatca 765840
actgaatgat tactaataat cgtaactgaa gctaacccat tatcataact atatcccgtc 765900
ttcggattta agatatgatg ataatacttc ccttcaactt caaaataacg ttgataaatt 765960
cctgaagtta caaccgactg atcattaatt tttaatttta aaatatcact acttccttta 766020
ggatcagtaa taccaattgt aaaatcatca ctattctttt tccctacaca aagaacatta 766080
ccacctaaat tgataattgc actgtctact ccctgctcaa ttaagtattc cttaatttta 766140
tcagcaatat atccctttgc aacagcccct agatctatta tagtattagg attactaaaa 766200
ctaattgtac tatcatttaa agtaattccc ctatatccaa tcgacgtcaa agcaccggct 766260
attgctgaag tttccggcaa ttttggagta tcagctttaa aatcccacaa atcaatcaat 766320
tgtcctactg taatatcaaa agtaccatta gataacttac tatattccaa accaatattt 766380
ataactttag caagttcctt ggatatttta attagtttag ttttatcttg atgattgagc 766440
tgatataatt cacttttggg attagtccgg gaaaagagaa gctcgtagtc cttgcaaata 766500
gcaaaacatt catctagaat attagacgaa gcacgatcat ataaagtaat cgtaacttgc 766560
gtatctaaaa gaagctgcgt ttgacttaga ggctgtttat tcgtacatcc acaaaatata 766620
attaagatta ttaaaatttt tataaaccaa cgttttttca tgtcatttcc tttcattctg 766680
gaggtagcta tgtttaagaa gaaagacttc attattattt tcataatttt tgtcgttatt 766740
atcggggcac tgctttttaa tcatttttat ttcagtcaaa aagctgctta cgtgaaaatc 766800
accgttaata atcaagtata tcgtactgtt cctctagaga ttgatcagac aattaagatt 766860
agtgataaaa atatgatcgt gatcaatcac ggaagtgtac atatgaaaga tgctacttgc 766920
cctgataaat tatgtatcaa acaaggaacg atatctaaaa atggtgaaca aattatttgt 766980
ttgcctaatc aagttgttat tgcaattgtt tctaatcaat ataacgatgt tgattcatca 767040
tccaaatagg aggccccaat gactaaaaga attacctatt tatctttact aatcgcaatc 767100
gcaattattc tcggttatct tgaaaccttt attcctatta actttggaat tcctggtgca 767160
aaactcggcc ttgctaacct catcggatta attgcactat atcgctttgg atttagagac 767220
gctttaatca tcactctcct gcgagttttt attattgcca gtgtttttac taactactat 767280
atgtttttat atagtttaag cggtgcttta ttaagtttag tcattatggt tcttttaaaa 767340
aaaaccaaac tcttttcaac tttgatcatt agtatttccg gcgcaatctt tcataatcta 767400
ggacaaatcc tagtagcctt aattttctat ggttttaata ttatttatta tctaccttat 767460
ttaataatct tatcacttat tacaggtagt gtcattggta tcttaggcca aattatttta 767520
gccaaactac ctaaacaact atcataatga attgtttttt actaaaaaaa ggaatttctt 767580
ccttttcaaa caacaatata actctcattt ttagcagcaa atgaaatgat catgtaatat 767640
tttatattgg gagagaaaaa taatctacat gatcacttac tttgctacga tagtactata 767700
ctccttaaac attactttaa gtcaatcttt ttttattaaa ctaattgccg attcatccat 767760
tttccactaa aatagcgcca gataaagaaa atacaacgaa ctccccaatc aataaacatt 767820
gcaatccaaa caccaattaa tccaagattc atatattgtc ccaaaacata actaaagcat 767880
aatctaaata ttagcattga tgcagctgaa actatcatcg taaacttagc atcatttgct 767940
gctcttaaag catttggaaa tgtgaatgac gtaggccaga ttaatgctgc aataattgca 768000
tgtaaaaaga tacattggta tgcaaggtcc gtcgtttctt ttgataatga atagaatgtt 768060
aaaattgaag gtgttgcaat aattaaaact acaattaatc cagccattga aagataagta 768120
atttttaata actttttaac ataatatttt gcttgtttat aatcatttgc acctacacat 768180
tgacctacaa ccgtcaccat cgccaaagac attgccatcc caggaataat ctgcatttga 768240
gccaagttat tcgaaacagc attagctgca attgaatatg tcccaaaagt tgcaattaaa 768300
ctttgtacta agattttccc tagctgaaac atcccatttt ctaatcccga aggtatccca 768360
attgctaaaa tcttttttat atacataaag tcaaatttcc aatgaagata atcatttaca 768420
catacatcat tatcccgatg acttaacatc tttaaaatta cgatacaagc tactgctctg 768480
gcaatcagcg ttgctaatac ggcaccaaat accccccatc taaaaacgaa aataaaaatt 768540
gcatttaaaa taatattaat aacattcatg actgcactat taatcatcga tattttagag 768600
ttaccaattg ccctaaataa tgctgctcca gagttatata atgcaataaa aggatacgac 768660
attgctgaaa ataaaaaata gatttctgca tttttcatta catctacttc aacatttcca 768720
aaaaccatgt gtaataatgg cacattaaat gcaataacta tcaccatgat aattactgac 768780
aataatgctg taatcaaaat caactgtttt gctgaatact ttgccttatc tttagaaccc 768840
tgtccaataa actgggctgc aactactgct ccccctgttc ctaatgcagc aaaaatattg 768900
attaataaaa tattaattgc atcaaccagc gaaactgctg atactgctgc ttcgccgacg 768960
ctagcaacca taacagtatc tgcaaaacct acagtaatta ctaataattg ttccacaacc 769020
aagggaataa ttaatttttt taatgctttg ttatcaaata acattcctca cgccccctac 769080
agttacctat tatacgccca tattcttttg aacaaagtaa atttcatttt ctggaaaagc 769140
aaaaaaacct cacaaatgag gtctaaaaac aaattattag tctaacaatg cttaaacaaa 769200
gttatcaatt ctgttgaggt caagtctcga tattccccta aagctaattt ttgatcaagt 769260
tctatacctg caaaagcaat tcgtttaagt gtacacactt cattttgaca tgatttaaac 769320
atttttttaa tttgatgata cctcccctca ttgatagtta ctaaacaatg gtattcatca 769380
agtatttcca ataaactagg taaacattga accttgtgat caatcactac accatcaaag 769440
aattttttaa tcaattcatc tttaagcgga aatttagtag tcacataata ttttttatta 769500
acatgatttt gtggtaataa taattttttt gatagtgaag tgtcattagt aattatcaat 769560
agccctgttg tatcaatatc taaacgccct aaacaatagc aatcttctcg cccaatcaga 769620
tcaattacac actgatgata tttatcatga tttgcacaaa gatagtcagc cggtttattc 769680
atcatataat aaacaaatgg ctgggcattt aattgaatat gatgatacat aataatatca 769740
tccgccttta ctggataacg aacatctgta attacttgat cgttcaccct aatttcccca 769800
tgcctaatca aggttttaca tatcttgtga ttccctagtt tattcttcat taaaacataa 769860
tatagatctt taattcgact cacctccatt ttagaacttc tttagcaaac tttttagctg 769920
cctggatatc ctttttatca ggatgtccaa agtttttaaa aataaaagca cttcctttac 769980
atgaaaacac cggtccataa attattccct tttctttaag ctgtgcttta acattagtaa 770040
attgatctgt tccaaaaccg ttagcagaaa ataaaataac cttcttaact ttattagcat 770100
caagttgtgc tacaaaccta gttacttgtt caggaatatt tcctcctaaa attggacatc 770160
ctaaaaataa aatatctgct ttaacatctt gcacttgttt aatattttta gcatcgactt 770220
gaagttcgtc agcaattgcc ttcgcaattt tcttattatt ctttttactt ttatatatta 770280
cttcaatcat ccttctgccc ccttttgacg atttttaaaa aatacttcta aatgatcgat 770340
cccatgcatt aatttaattg ataactgata atactgagtg atttcttcat tactaaattc 770400
actaaataaa gcttgatgta cctcatctgt taattcttcc atatcttttc taaagcgcaa 770460
tccctgttta ctcattacca cacataacga acgtgcatct ttgggtgact tctctaaaat 770520
cacatatccc tgcttttcca aactcagtgc taattttttt acattttgtc gtgaacaccc 770580
catcactttt gctaacatgc ttaaatcagg agcatcagta aatgaagtca tcgtagccat 770640
taataaccat tgtttactcg tcatttcatt gtaacgatca aatatcgcat gtaacttatt 770700
ctcctgaata aacacacccg caaataacag ttttttgacc catttaggat cctgtcctaa 770760
taattcataa cttgattttt tcatcattct ctccatatcc gtaactagtt acttattttt 770820
attatagtaa ctagttacca atctgtcaat aaacaaatac tttcatcaga ttatttcata 770880
ataaaaagtt ataatgactt ctcactataa cctctaaaac agatatttta attttcgatt 770940
gatcttatta ctttacaggg atttccacaa gcaacactat taggagcaat atctttagtc 771000
acaacactgc ctgctccaat tacacagcca tcgccaatcg ttacccctgg taaaataact 771060
acattaccac ctaaccacac attattacca attttaattg gtagcgcttg ttctaaacca 771120
gtatttctaa ttttatattc ggtaggatga atagcagtat atagaccaca tgaaggtcct 771180
atataaacat tatctcctaa ttcaattcca ccaccatcca taaaataaca attactatta 771240
ataaaagcat ttttaccaat tttaatctta tttccataat cacacataaa gggacttata 771300
agctctatgt ttataggttg ataacctaac aaacttgtaa tcacttctaa tcttttttca 771360
taactgctag gttttatgtg atctagatca aaacacaaat ctttagctaa tactctttgt 771420
tttaataatt cttcatcatt atttgcatca taccacattc ctaattccat tttttcacgt 771480
tctgtcattt ttatttcccc tttattcctt cttttaacca tttcatacta atctctgcac 771540
taggataccc tgcaattaaa attgcctgtg catgtacacc ataatcacct gtttgtacca 771600
ctgctttaca acgatcacgc atttcataat attcaggaat gtaatgcatc gaatgaatat 771660
ttttctttcc caacaaatca accagtaact gataatcttt ttgatttact tcaatcatat 771720
cttctgtgac gattgctcct tcaaaatcac cacaagcaac tagtgtagtt actatatcct 771780
caaaacttgg tgaaccggtc actacttcta catctatata ttcaacactt gaatccagtg 771840
ggtatagggc tttactagat gttccactgc cagcatcagc aataaataac atctcaccat 771900
gacgcagact agcaacaact gctgccaaac gttcatgaag aattctcttt tttggtttca 771960
cacttatctc cttatttatt aaaagtcttt tattaattaa taattataag ttatctaata 772020
aaaaagtcaa caaataaaac aactgtcctt gaaccgtcct aatcaaataa atagatgaaa 772080
caatcaaatt attagatttg aagttatcaa aaataataac ttcatttatt atttagaaat 772140
aaacaggtta agctatgcaa atattattac tatagtgttc agtctcatat ttcataatct 772200
ttttattttc tggtattgaa catcaaactg ataaatctga tgataatact gttcgtccaa 772260
caaacatata aatccatatt tctctttcaa ttcaaggaaa gatttatgat tatttagatg 772320
ttctttgaca atttctaatt tatacgcttt agcatacttt tgtcccctca acaatataaa 772380
agttcctatt cagtgtttaa ttatttacac tatctaggag gtttttatat caataacagt 772440
tgttttattt gtcttgttta atgaaacttt ctctaataac ttcctgtatt cccaataaat 772500
aatcattttc ataattagca caatacgtta attcaggcat aaattcactt ggtaaatact 772560
ctaaacaaat cttcttgatt tttaatatat catcagcctc aatagcttca cctgttaaaa 772620
tcacgattga aggatttatt atcgatgcta cacaacataa tgataaagcc acatcttctg 772680
gtgaataatc aaagcataac tgttcttgtt ttaggtattt aaaaaatggt aaatataaga 772740
tttcaccagc aatactattt tctccttcta ttaatttacc attaataaca ctcccacagc 772800
caggtccaga atttaatgga aacgtcacat aacaaagatc ctttttatta ttatgtaaat 772860
agcagccata agcagtataa ttcatatcat ttttaacaac tgtctttaat cctgtagcct 772920
tctcgatttc agctttaaga tttacatttt ttaaattagg aatatctgat tcaattacta 772980
tctctttaga aattattgcc ggtaccccta aaccaattat ttggattctc gaatcttgtg 773040
ataaaagata tttaatgaat tttaaaatat cctctaattt taaatcattt actaattctt 773100
taccctgttt tagtacactt gcaagggcat caatgatttg ccagcaaaga taatctctgc 773160
ctctttttct ttgtacaaat aaacacaatg aatgaaaata ttctggattc aatccatatt 773220
ttttagtagg acgacctttt tttaaataaa taatttcttt ttcaacaaca gttccattat 773280
ccaaaaaatc attaagaatc gttcctactg tagctactgt caatcttgaa taattagcta 773340
gttctttttt tgtcacttct tgatgtctta ataacaattt caaaatgatt tgatcattta 773400
aatctcgtag ttttccagtt ccaattctat tcacatttat cagccctttt caattatttt 773460
tgattatatc agtattttta aaagaaaaat accctttgtc tccaaagggc ttttaattca 773520
agtacgtcat taacacattc attattatat gataaaaatg tcttttgggc aactgacaaa 773580
aagagaatat ttaatttttt tatttttata ttgacttata gttaactcta agttctatac 773640
tataaatgta gaaaagataa atacatgaag gaggacttaa aatgaaaaca tggttaatta 773700
caggatgctc tagcggaatt ggacgcggca ttgctaaagc ggtattaaag aaaggggata 773760
atgctgttgt tactgctcgt gatacaagta aaattgccga tctagtcgat caatatccaa 773820
atacagcttt aggagtggct ctagatatta ccaaaaaaga gagtattagt gctgcagtaa 773880
aacaagcaca agaaagattt ggaacaattg atgtattgat caataatgct ggatatggat 773940
atcgttcttc agttgaagaa ggtgacatag atgatgttaa tcttttattt aatactaact 774000
tctttgggcc aatcgaacta attaaagaag tattaccaca aatgcgagct aacaaaaacg 774060
gtgctattgt caacgtatca tcaattgcag cggttagatc gggtgtaggt tctggttatt 774120
atgctgctag taaggctgct ttagaattaa tgactgatgg tctagctaaa gaattaaaac 774180
cgctaggaat caaggtcatg atagcacaac caggttcttt ccgaactaat ttttatgata 774240
cttcactaaa agggactaaa aataagatcg atgattataa cgaaacagct gggaaaactc 774300
gtaaagagaa tgtcgttaat cataaaaatc aacctggtga tcctgataaa ggtggtcaag 774360
ttattgttga tacaattgaa aaagacaact atcctttccg tcttctctta ggtagtgatg 774420
ctaccaagat cgtagctagt gctttagaag aaagaattca agaaatcgaa acttggaaaa 774480
atattagtag tcaatcagat tttgaataga agtaaagcct cctaataacc ggaggcttta 774540
ctttgattca gttattaaaa tgtccagtac aaaaatgttc aattatttct aaaacttctg 774600
ttaatttatc tgtttcaata taaacttgag tctctttaac aaatttatta ataaaattat 774660
catcaaaatt tccatcagct tgtcttttga aactttcttt taataaatgc tgtgctgcat 774720
cttgatactc aggtttcact ctttttaaat aatattcata aaacttagtt tgtccatctt 774780
tcacattcca ttcactcctt gcatctatca ttaccacaat tactttaata atacttagta 774840
atctcatttt tattcattgc ttatacatat aaaatcattt ttcctaataa aatacactcc 774900
tttaaactaa cgattttcac aatttccaag atatattttt ccatttcata aactaactta 774960
tctacctata atgtaagtta acacgaaaaa gcaataatcc ccggctctaa gacactaaca 775020
atcaaaatct tccagaaata agagaagact gccatgatta attatatctg gcatacttat 775080
cccaattttt ctaatatctt ggtattttat taatataaca tttaaaatat catatatatc 775140
ttctaaaatg gttcaattct tagtaagttc ttcatcaaga ataataatat tttgttcatc 775200
ataaatacga tgcatcaacc aaacccgctc actgattcta atgactgaga tacataagat 775260
cttaacacct ttatgggttg ccattttcaa tgacaagggt tcaagtgata taactttttc 775320
cctcaatatg atcaatctta tcttcaatca atgtaagagc atgtctagca tcatatttag 775380
taaaaatttg tggtgcttaa aacaattaca tcatagtgat ttcctactgc aaatagctta 775440
ctataagata tcgtaaagaa ctagttgtta atccaccagt acaactgagc agtactctaa 775500
ttagtggccg tataaccagt ttttatactc tctactattt tttcaaatac cccaatcgtt 775560
tgcttaagcg tcctcacttg aaaatgcaaa taaaaaatgc gcaaacccaa tatctagatt 775620
tacacattac tgttacttga ttattcgaat tataacaact cagtttatta aaagccaaga 775680
aaagattatt ttactaaaat aaaaaagcct atacggctta ataaaaaaat aaaaatagtc 775740
actgattaaa acaaatagtg tcaatagata ttttagggag tagtgactat ttatacaagt 775800
tatctacctt gcactattat aatctctcat gaatgttaat ttaatatgaa ttaatcaacc 775860
tttttataaa ttattttatt tatttttgaa atttaaaaaa gtgcatcttt ttaaagatac 775920
actttttatt atcaaattat tcagcagctt ctgcagcttg tttgttttga tatctttcat 775980
aagcaattaa gaatggtgca taaattaaga tagatgctac gattgcaatt gcttgagata 776040
cagcacccat gatattagct cctgtagtta agaaaccatg taagataggt ggtgttgtcc 776100
aaggtgtatt gattacagct tttggacaga atccaattac agttaataca taaccaagca 776160
ttaaagtaac gattggtgct aatacaaatg gaatacctaa gattgggttt aataccattg 776220
ggataccaaa tgtaactgtt tcattgatgt tgaataaacc tggtactaat gagatacctg 776280
cgattgtacg gttatcttca cgttttgaga aaactaagat agaaattact aaaccgattg 776340
taaccccaga accaccaaat tcaccgaaca tttgtaacca tgccattgcg aagatgtgta 776400
aatcatcacc tttagcatta tttgttttag agaatgtttc gatattttct aacattaatg 776460
gtgtaaataa tgcttctttt actgcagcta acatgttgtt accatgaata cctactaacc 776520
agaataatcc gataatgata taaataatga ttacccctgg aatagttgat ccaattgcac 776580
ctaaaggtcc ttggatataa gttgaaatta cgtcatttaa atataatcca gtaactaatt 776640
cacatccacg tccaattaac gcaatgattg ctaaagtaat tacagctgga attaaaactt 776700
cgaatgcacg agcaacacct ggaggtactg tttcaggcat ttttaatttt aatccttcta 776760
ctttacgtaa tgcacagaag atttctactg aaacaacccc aacgatcatc cctgtaaata 776820
aacctgttgc tcctaaagca ccaccagcaa cacctgtaaa tgtttgtaat gctccatcag 776880
ctgttaattc taatgtttgt ttagcagtgt ctactaatgc atagttagcc catccacttt 776940
gagttactgc tagccagcaa gcaagtccta ataaacctgc gaagtatcca gtttcaccat 777000
tagcttcacc gatttcttga gcgataccaa aagtaatccc aactgtgata caagaaattg 777060
ttgcgaattg cattgctgca aacgctgggt taattacttc taaagccatg ataggtttcc 777120
agaacatacc taaccctgaa tctgcattaa ctaatacgtt acaccataaa accccgatcg 777180
cacctgcgat agtcaaaggc atgaatgttt ggaacgcatt tttaattgca gataaatact 777240
tattttgccc acaccacgca ccaacgcggc caaggacatc tgccattttg tccataattc 777300
ttttcctccc ttattgacta cctaataata gcaaagggtg aaatacttgg aaacgctttc 777360
cccacattct gtaagagtct tacaattttt ttaaaatatt taaaaatgat atgtaaattt 777420
attacatatc atgatctgtc tttttttcat atttttgttc acaatttatc tttctaatta 777480
agttaggata atagtctttt tgaaataaga ttgaaaagat tagatccatt aaataatcac 777540
tacttaactt tgaagaatag gtttctattt tcgaaacaat attttcttta ctacacattg 777600
ttaagcaata attcgcccgt tttcttaaat aactatcatt tattgaagta attgcaataa 777660
tagttccctt attatccaca atccgatcaa ctatcgtttt tatttcatga ctctcaccag 777720
aataagatat cacgattgca actgtatttt tatttacaaa taaagaacgc ttatcttgat 777780
catttggtga agatttaaaa ttaacaaagt gatcgatcga aatcatccga tgctcgaata 777840
atagtcccga aagatacgaa gctccaacag caaaaatatc aataactgat gtttttaata 777900
acttttcaat tacttgatta agtacatcat agtcgagtaa tgctttagtc gcctcaatcg 777960
tatctttata taactcgcct aactgatttg tgacttcttg aatactatca ttctctttaa 778020
aaggtcgatt gtaatcaaca tcagtttgat aactagttaa aactgatgaa gcaaaattga 778080
tcttaaagct attgtagttt ttttcaccca gtttcttgca aaaacgactg atcgtcgctg 778140
ttgaagtaaa agtcgcctca gctaactcaa ctaaacgcat attagccact tcttctttat 778200
gatcaattat ataattagca atcccttttt caatgtcact aaatcctttt ttgtattcca 778260
gttttgataa taaactcata aactaccccc gaattacttt ataaatattg tcccaaattt 778320
ttttccatta taacactaat aagggcatgt tagtcttttt taacactatt ttaacactat 778380
tcttttttga tttttctaaa ataaaaaagc ccttttggac ttttcatcat ttagattaaa 778440
tagtcactaa attaaaatat gaactgtcaa tagatatctt atgagagtag cgactatttc 778500
tacaagccaa ctagcctgtg gaaatataat actccattgt tttataaaaa aatataaatt 778560
tatataattc aggatagtat tttcaaaatt agcaatttta aatattaaat tatgaaaatt 778620
ttttacataa tttatttttt attttcaaag tcaattactt ttaaagcagt agtaacatta 778680
ctttgataat cctttacaag taaagacaca aaaatgacat ctagaacata cattgttgca 778740
gtaaatgatg taatcacttc taaactaagg atatcttgtg acgagtaaac attgaggtaa 778800
atatcacaat agttttgtaa ttcacccttt ttaccaccaa ttgcaataac atagattcct 778860
gcctttttta aatatttagc aatcttgatc atctcactat tattgccagt aaaagaaata 778920
agtatggcta cacattgacg actatttttt tgtgataaaa tgaaatgttc attgattcca 778980
ctatgtgcat cgcactcttt tcctaaagtc atgattttaa aagcagcttg actggcaatc 779040
gtataactaa ttcctgttcc ataaatagaa atacgtttag cttgagataa acgattaatc 779100
acctgaatca ttttattttg atctaaatcc agccttgtct gtactattga tttatcataa 779160
atagttggga taactttaac aatatcttga tatgtactgt tttcatcaac cggttcatct 779220
tttaaaagac tactaattcg acttaattca ttatactcaa attcaacctg gcgtttaaat 779280
tcttgataac tattaacctc cagcttttta caaagacgta ttactgtagc cttactcgta 779340
taagtttctt ttcctaattc ttccactgat aattgatata actgttcagt atgttttaaa 779400
acatactctg caattagctt ttcgctatta gtaaagcgtt tcctctccct tagcttctct 779460
aagatcatca ctatcacctc atcttttcct attatgacat agatatcaag atgaaacaaa 779520
tttgaactaa tcaattatct ttttattaat taaaataaag gagattgaaa atcctcctcc 779580
attttacaaa acagctaaat atcatttaaa ctttcaccgt tcgttgcaat aactttttga 779640
taccaccaaa aactcttctt gggataacgc gccaacgttc cactaaaatc atcatgcaca 779700
tcaacataaa tatagccata acgtttagat acttgacatt ttgtattagc aacaatatcg 779760
attggacccc aacttgtata accgagtact tctacaccat ctttgattgc ttctaaaacc 779820
tgctttaaat gctcttttaa ataatcaata cgataatcat catttactgt ataaccatat 779880
tgttcatcta caaccaaaat atcctttgct ccaagaccat tttcaacaat aaataacgga 779940
agctgatatc gatcataaaa ttgattaaga atatatcgca accctttagg atcaatctgc 780000
caaccccatt cagattcttt taaataggga tttttaactc cgctcattac atttccccga 780060
gcttgttgat taagtttctc atcagctgta gcacaataac tcatataata actaaaagaa 780120
ataaaatcga ctgtattttt taaaatttct tcatcttctt tcgtgatttc taaatgaata 780180
tgattttctt caaaaaaacg tagcatgtat cctggatatt ttcccctaac atggacgtca 780240
gcaaagaata gtgactcccg atcacgtcgg actgtttcct gaatatcttc aggctgcggg 780300
gtcaatggat agattggact ccctgcaatc atacaaccaa ttttaaaatt cggattgatt 780360
ttatgagcta tttttgttgc ttgagcactt gcaacaaact ggtgatgaat tgcctgatat 780420
aaaacttcgg gattaatttg atcagctttt cctttaatcc caccaccatt aaagggggca 780480
tgaagaataa catttatttc attgaatgtt agccagtact taaccttatt acaataacgt 780540
tcaaaacata cttgagcaaa gttaagataa aaatcaatta ctttacgatt cacccatcct 780600
ccataattag tcgctagata taaaggcatc tcgtaatgtg ataatgtaac taggggttgt 780660
attccatatt tagctaattc atcaaaaaca tcatcgtaaa actgcaaacc cttttcatta 780720
ggaaccgtct catcaccatg cgggaaaata cggctccatg ctatcgataa gcgtaatact 780780
ttaaatccca tctgagcgaa caatgcaata tcttctttat agcgatgata aaagtcaatt 780840
gcatttttct ttaaataatt atctaatggc ggaattgctt cattaccaaa taccccttca 780900
ggcaaagcat cagccgttga ataacctttg ccatcttcta agactgcgcc ttcacactga 780960
ttagccgcta ttgcaccacc ccataaaaat cctttaggaa aatttttttc taccatcttc 781020
atgactacac ctcttgcaat ttatttagtg caaaagtcaa taccgctttt ccatccatct 781080
tgccataatc gcgcatatct attaaatatg ctggtactcc attagcatca tccgcaatac 781140
ttttttctag ataacgcacc tgtggtccta aaagaataac atctgcatct tggctgtgat 781200
tttttacttc tgttgctccg actgcccaga tttttgtttc aattcctttt tcctgtgctg 781260
cttgttccat ttttgtaact aatagactag ttgacattcc accagcacaa cataataaaa 781320
ttcttatcat tttaattttc ctccatctca tcaattcttt caattttaaa aattactggt 781380
cttgtcccat cactacaaca agcaatcatc atcttttcat cattagtcca gcctttcata 781440
attgagccac cttgcaaagc tgcataaata tagcgactga cggcatccca agcctcactg 781500
caaaactttc cattcatcat attccaaaaa tcatctttgc cattaccacg ctccaaaata 781560
aattcctgtc cctctttaaa caatggacat ttaccaactt gcggatccgc taaatattga 781620
tccgctaaat cttgataata ctctcttcgt aataccgtaa ttttacactt agacatctgt 781680
ttgctccttt caaatccttt tttctacact tttaatttaa catcagaaaa taaaagaaac 781740
aacaggctcg taaactgttg ttccagtgtt tcatttatat attattttta taatttattt 781800
tgatacttgt ggtccactaa aggcattttt taatcgttct aaagcttctt ttaagaccca 781860
agtagggcaa gcgatattaa ttctttcaaa cccttctcct tcttgaccga agacatatcc 781920
ctcatctaaa tatagatcag cagcaatcat tttcttctct aattctagat agtcataacc 781980
taaatttcta aagtctagcc aagctaaata tgttccttct aatggatata ctgtaactga 782040
tggaaaattt ttcttgataa agtctaccag tatgtcatag ttatgatgaa tcaatgtctt 782100
aaattcagct aaccatgcat ctcctttagt ataagctaac cgtgttgctt caaaagataa 782160
tgtgtttaat gtaaaaaatc cttttttctc ttgttgcgca ataaatttag ctcttaattc 782220
tttattctta ataataatat tagatccttg caaacctgca atattaaaac ttttacttgg 782280
tgctgtacat gttacagtaa tatctccaat cacttcactt aaaacagcaa ttggataatg 782340
tgtatacccc ggcatagtta aatcttcatg aatctcatca ctaagaatta taattccatt 782400
atttaagcaa atatccgcaa ttttttctag ctcttctttt ttccatacac gccctacagg 782460
attatgagga ttacaaagaa tcaataactt tgtatttgct tgttttgcaa gttcttcaaa 782520
tttatcaaaa tcaatttggt aactattttc atgatttatt aaaggacatc tttgtactcg 782580
acgattattt aactcaattg cccgatagaa aggataataa actggcgtaa aaataattac 782640
tccgtcattt tcttcagtaa atgcagttac cccatcgctt aacgctggta ctacaccatt 782700
agataaaacg atccattctt tttcaacttg ataattgtgt ttatccttca tccagttaat 782760
tactgcatcg taataagctg ctgttccatt tgtatagcca aatacaggat tattctgcat 782820
aaattcaagc atcccttcag caatctctgg tgctaatttc aaatctaaat cagcgactga 782880
aagtggagct atatttttag caactgcagg attatgatct ttcatcccgt tccatttagc 782940
agaaccattt tgactccgat caactaatgt ttcaaaatca tatttcattt ctctacctcc 783000
attattaagc acctatatag ttaagtacct taataatagt atactctcac aatttataaa 783060
gtcaaataaa aagaatcata acgattcttc attgtcttgt gcatattctt tatttaaagc 783120
tctttgaacc ttaatataaa tatctatttc ttcattgcta aaactaatta aattcttaaa 783180
ataacgtttc ataattttct tatcaaactg accatgtaaa tcaaaaatct gcctcccgcc 783240
aaccgttaag tataaattat actcacgatt attatgagga ttcttggttc ttgaaattaa 783300
tcctttttgt tctagcttct ttaaaatttg actgctggca cttaatgttt tttttaattc 783360
tttagcaatc atcgaagcat ttattccagg gtgatttcca attattgcaa gagtgtgagt 783420
ttctactgga taaagcatca ctttgccaaa ttgtcgaggt ttactatcat attcttgtat 783480
taaatcataa ctttcgtcaa ttactttaat catattatca aatcgctctt gatccacaaa 783540
aatcacctca ggtatcattc tatcaaataa taaccaatgt tgcaaacaat cataaaaaga 783600
ctggttttac cagtctttaa aggattacat taaatgtgat tctttggttg tgtattcttg 783660
aactactttt tgaatctttt gtggagtttc tggttctaat ggataccagc ctttagaata 783720
cataagatca aagacctcac gttgaatctg atatacctct ttttgaatat ctattaattt 783780
atttgctagt tgttgatgag agcattcaat gataaaagtc gtataatcac ttaataatga 783840
ttttaaacat aatagaacat cattgattct atcataatca ttaaacgtat tttcatttgg 783900
taaaattggt tgtttcgttg gatttgaata attttgatta tccatttaaa caccccaata 783960
attcactata atgattttta attgtgctat taacacgtcc taaagtcatc ttaatatcat 784020
tatcttcaac actttcttcg taagctttta acttcttcga taatacatat aaactattca 784080
attgatcatt aaaagagcca ctatctttag tagatatcat ttttggtggt tgattcataa 784140
aattcctcct tcaataatat tttggttctt ttataaaaca attatgcata atcatataca 784200
aaagattaaa ataaaaatat tttttatttt ctacttataa atttttcaaa tctgactaat 784260
actagagtat ctttattaaa aaataaaaaa cattattatc ttcaataatg tttctttacc 784320
aaattaacag ccctaaattt ttatcctgct acttttattt tattttcaat atatgccatt 784380
actgcttctt tagggatatt taataccgct gcaaattctt gatgcagtag atcttctgct 784440
tcttttttgt accgctcatc agtttgactc aatcgcttat tttgtaacaa taaatttttt 784500
tgctttgctt gaagattaca aatcaattga atcaagccat cacaagtata ttgacttatc 784560
gtttctttgt aataatctgt taattgtctt aaattttgat tttcaataat ctctttttgt 784620
actttaggat gtctggtcaa taatcgttct aactcctcta tcgaaatcaa atgacgcata 784680
tatacttgcg tatcaattgg cacatacgtc ttaccgtcca taaaaatagg atttaaagta 784740
taatactttc gggaattggg ctgcttacca atactaatta ctccaatatt ttcaatccta 784800
caaacacttt gattaccata tataatcaaa tctccttttt catacacata accacctagc 784860
tttctattaa gtatatgctt aatatatcta ttataccgca ctattagtta ctatatgcaa 784920
aagtaattaa aatatactaa attttctttt ttatgcagct aaagactaca tctttttata 784980
tttgatttta ctatttaaat cttgttaata atttcaacag ttttacatgt ttcgtatatc 785040
attagggctt gctttagcaa tgatggtgac agtatttttt agctaaaaac ctttattgtt 785100
gtaatatcgt taatccaact agaatttgtt aaaacagtaa gatagattga ccatcgttta 785160
attggtattt cactttccat tcaatatttt attcctaatg aagatactat tttagttgaa 785220
atattattag gtacttcggt ttatttttac cagaatataa atataaataa attatcaata 785280
ttgacagtgc gctaaatata tcgatcgatg gttcttttag atactaaaac agcaatagaa 785340
aatcaactta ttagtttaat cagtgaaata tttatttcat gaccaaacta atattatcta 785400
ctaactaaaa aatgcagacc attgtttgcc tacatttttt gtgcatattc ttttactatt 785460
ttagaaatca aatttaacaa agcttcttcg tcattaactt cataatcagg tttaatatcc 785520
attgctttaa gtcccttttt atttaaccaa atacatttcc aattagcatt tttggcccca 785580
atcacatcat tttcataaga atcaccgaca tagatacaat ctttatccgt aattaaatta 785640
aatatctgtg gatctggttt tgaataacca acaaccgatg aaatgtagat atcctcgaga 785700
gcaacccagt tgctcatctt tagtctacgt aatttttcca tttgatgaca agcaggtcca 785760
ttagtaatta tccctattcc tatatgatta tcttttaata aatctaatat atctttgatt 785820
gcattactag ttgtaatgtc ttgttgatat acataatatt ttgtttgaaa tgctaaagca 785880
tgtgcttcat caatttcaag ataatattct tttaaggctg cttggatacg atagatatac 785940
atttcattta ttgtaacttg accagactgg cttgcctcaa atattttatc actatattta 786000
cgaaatttga taaaaatttg atatataggc aaagtcttta ttttaggaaa tatttcaata 786060
aatgcctttt taaatggaat gaactgatca tatagcgtgt catcaacatc aaaatagaat 786120
ttcatctttt taccgtttat aatttattaa tcatttttac aacattatct actgtaaaac 786180
catatctttt aaacagttca tcagcaggtg ctgaagctcc gaagctatcc attgttatat 786240
atttgccttt taagccaaca aactctcccc aggacattct tgaacccgct tcaattgcga 786300
ttctcttttc tatacctggc ggcaggatac tttctctata ttcccggctc tgctgtttaa 786360
atatatccat actcggcata cttactaccc ttatcgcttt gcctctgatc cgtttctttg 786420
cttctactgc cagtgtcact tctgatcctg aggctatgat gattatttcc ggtgttcctt 786480
cacactcatc aataacatat cctcctttta atgcttctcg gctagatcct ttgatctgtg 786540
gtagattttg tcttgataaa accagtgctg ttggtgttgt ttttgatgtc atcgccagat 786600
accatccagc attagtctcc tgtgcatcgc acggtctaaa tacattgaag ttcggcatcg 786660
ctctcagcat cgtcagctgt tctaccggtt catgagttgg tccgtcttca cctacaccga 786720
tactgtcatg cgtcaataca tatatcagtg gcagattcat caaagctgac aatctagcca 786780
tcggtttgac atagtcgctg aatacaaaga acgttgatac aaaagtcttc aatccaccat 786840
aaagcattat tccgtttcca atccctgtca tcgcctgctc tcttactccg tagtgtaaat 786900
tccttcccct gtaattctcg gcactaaagt ctcctacttt atttaaatat gtttttgtag 786960
atggtgctaa gtctgctgaa ccacccatga aatttggaaa tagttccttt atccggttca 787020
tcgcagttcc cgacgaattt cttgttgatt caggtttatt ttcaaatttc cagaattcca 787080
catcgttttc aagtacttta ttatagtcca cctcaaaata ctgcttccat aattttttca 787140
tctctggata tgttaccaga tagtcatcaa acatatcctt ccaaatctta tagattacct 787200
cgctgcgttc ctgctgtttt gctgtattga gataaacttc ctcatctatc gcaaatgtcc 787260
tatcctcatc aagtcccagt gtccttttta attccctgac attttcttca cccagtggct 787320
ctccatgtgc actggctttt ccctctttag ccggacatcc ttttccaatt ctggttttca 787380
cttcaataaa ggccggcttt tgagataccc tagcttgatt tatcgcactt aatatttcgt 787440
caagatcgtc tccatcttca accgtgaatg tatcaaaacc aaatgccttc attcttccct 787500
gaacatcttc tctaaaggca atatccgtgc ttccttcaat cgaaatatta tttgaatcgt 787560
ataaaacgat cagtttctcc agttttaaag tgcctgcaag tgaaaatgcc tctgacgaga 787620
ttccttccat cagacagccg tcaccgccta gtacataagt aaagctgtca aatactggat 787680
atcccggtct attaaaaatc gctgccaagt gtgcctgggc cattgccatt cctgttgcca 787740
tcgccatccc tgctcccaat ggtcctgtcg ttgcctcgac ccctacagta tgtccgtatt 787800
caggatgccc cggagtcagt gaatcaagct gtctaaactg tcttagatcc tctatcgtta 787860
atccatagtt atacaaatga agcagactat aaagcagtga tgatccatgt cctcccgaca 787920
agataaagcg atcccggttg acccacttcc gatgtgttcc actatgtttc atgacctttc 787980
cccataagat ataggccgcc gccgctgaac ccaaaggtag tcccggatgt cctgaatttg 788040
ccttttcaac agtatcagcg cataatgctc taatggtact gactgttttt ctatcaactg 788100
cttccatatt agcctccaaa tactgctcga tagtcttttt ggaatttttc aatcccctca 788160
gcagtcaaag gatgtttcag catttgttca ataacactgt aaggaacagt tgccagatcc 788220
gctccggctt tagcacattc gataacatga caggcgtttc tgacactggc tgagatgatc 788280
tgcgctttga tatcatgcgt tttgaatatt gcggcaatat ctctgatcag ctgcagtccg 788340
tccatcgaga tatcatcgat tcttccaaca aatggagaaa cataggttgc tccggctctg 788400
gctgccagga ttgcctgcgg aacattaaaa atcaatgtca gatttgtttt gatcccttca 788460
ccggacagta cccggcatgc cttcaagccc tcagcagtag ttggaagctt aacaaccata 788520
ttcttatgga tttttgcaat ttcccggcct tctttgatca tgccttcagc atcaacagtt 788580
gtggctttga cttctccgct gataggaccg tcaacaattg cagcaatctc cttaattacc 788640
tcattaaagt ctcgaccttc tttagcaata atagagggat tggtagtaac accacaaata 788700
acccccatat catttgcttt ttttatttct tcgacattag ccgtatctaa aaaaaatctc 788760
attttatttt tctccttata tatattgtga taacacttct ttttcacatt cattaataac 788820
ttttataata ttattctggt tattacatga ttccagcttt tcaatcagct ttgcatcatt 788880
gaccattcgc attaatttaa caattgcagg aatatgttct tttttatctt tactcgctaa 788940
acaaaagata accctaactt gtttattatc gaaccatacg ggttcatcag ttacaatcag 789000
actcattgaa cttattttaa ccgatgatgt gttcccacta tgaaataacg caaatttact 789060
atctgttaca gcataaaacc ctgattcctt aatgacactc atcaagcctt cataatattc 789120
agatttaata catccatgtt gtattaaaat atcagttgaa agtttgattg catctttcca 789180
attgctaaat gatttaacat aacgaataca attttcacct aataaatcac ttatattata 789240
gtatttctta ggaatcctaa catctttata gccaagttct tctttaatta tttcaagtac 789300
tttttcacgc tcaggagaat ttaaaaatcc caatcttttt tcaattgcaa tataattcgt 789360
taaaacattc ttttttctaa ttcccaccgc ttctaattta ttatgatcat gattatcaaa 789420
aattgcattt acaacaatca aagttttttt tactgggagg attaactttg acgttgaaat 789480
aacaatatct atttgctccc atttctgata atgctctaga tcatacgctg gaatactatc 789540
aatcacttga acctgatatt catttcttag agtatctttt aaaagtgctg tagcgccaaa 789600
acctaagcca catattagta aaatattttt atagtcattt gctcttaatc tttgaatact 789660
tgcaataaaa tgaatagtaa tataaattaa ttcttcttga ctgatctctt gtaacggttg 789720
aatactcaat acaattgatt ttaaaacttc aaatacatat tcataacttt gtggaatcac 789780
tgtttgactt aactcataaa ctcgaatatt attttttatt cgttccaaca tcggtgccac 789840
atgattcaat aatcctttta ttaaaatcat atcccgtaaa aaaaatactc ctaactcatc 789900
agacatcatt gtcacaagtt gaattataat atcttcagtc attattaaat ccaaattgat 789960
atcaacctca ccatatttat tagtataact agaataactc ataattagtt ttttttgatt 790020
atcatctaat tgtttattaa ttatcatttc cagttcttgg agtgaataat cttctacatc 790080
aattttttta ggacaagatg gcaattgctt ctcttttata atataccagc aagtagttaa 790140
tatatttgct acataccaat caaacgaatc atcactaaaa gtccaactca tcattttcat 790200
tttattagtg atccagtcat aaatatgaag aatatcaaaa ttatagattc tatataacaa 790260
tttcattaat tctaattcaa atgtattata ttcagaaagt ttattactaa ataaatagat 790320
atattttttt aactcattga cccttaaagg atatccctta tgatcatctt caattaaatg 790380
aaaatgacga ttatagacta gcgatagacc atactgatta aattctttaa taagagtatc 790440
caaatcattt tgaattgaac gacgcgatac ttgaaatttt tcacttaact ttttaatatt 790500
tagactatga acatcaaaca taataataaa acgtaataat tgcatcctct catcagctga 790560
aaaaataaat tcactatctt ctaataaaat atttaaatct aaatcaattg ggacaattaa 790620
ttgtccttta gaacgctttt caatttcaga caatcctttt aaactcaaag catcgttaat 790680
acaatctatg tcgtaacgta cattacgttc tttaagatct aaagcattgc cgatttcttt 790740
ataactagat tctttttttt gatttaaaaa tctaataatt ttaaacattc tagcactaat 790800
catcccaatt tcctccgttt atttttcttc tttttctgct atatctaaat ttggctttgt 790860
aaaatgtaag attgctgcgg atactaatac tcctaccagc atcgctaata cataccataa 790920
tttgccattg actactggta aaataatcaa accaccatga ggaactaatg cttcgactcc 790980
attcatcatc cctagtgccc cacctactgc actaccaata ataattgctg gtaaaactct 791040
tttcatatct tttaccgcaa aaggaatcgc tgcttcagta attccaatcg ttcccatgaa 791100
taatgccgat attcctaaat tcttatcatc tgcactatat tttttacgat caataaaagt 791160
agataaagct aatgctaatg gcggaattgc acaagcaatt cgatgagcac catttggagc 791220
ataaacacct tctgccatca acgcaagagt aaatgccgtt gccgtcttat taattggtcc 791280
acccatatca actgctgtca ttgcaccaat gattgcacct aagagaactg catttcctcc 791340
ttgcattcca cttaaaaatt taacaagcca gtccatacaa gctccaatcg gaacagaaat 791400
aacgtaaata tagataattc ctaaaataaa tgttgtaaaa ataggaacaa ttaaaatagg 791460
catgattgtt ttaatcgtat ttgaaacttt ccatgtttta caccaacgaa ctaaataacc 791520
agttgctaac cctaaaatca ttgcgcctaa gaatcctgtt ttaacctctg attcaccaat 791580
tggattattt gctacatatc ctaagatcat ccctggagct atcccaggtt ttccagccaa 791640
tgaataagcg atatacccag ataaaattgg aatcatcata gcaaaaccag ctgatcctaa 791700
atcatttaaa tttttcatga aaggattagt tacttccatt ccagtatccg ttgctgtccc 791760
tgttgctaaa gcaaccgcta atagaatccc accaaccaca actgaaggaa gcatatacga 791820
aaccccagta ttaaaggctt tttgaatatc tttccatact ttattatttt tcataacttc 791880
ttctcctata agttttctgc ttgatctata accctaacgg catctttaat tacatcccca 791940
ggttcgactt gaattacttt accagcatct tgtttttctt caaaacgttc ttcaccatcg 792000
atccccactg caattgccaa aataacagca tccgcttcat caatttcctc ttgttctaat 792060
tcgttttcaa tccccatact tccttgagtt tctactttta cttcgtaacc acgattacga 792120
cattcttttt caattgcttc ttgagccatg tacgtatgcg caataccggt tgggcatgct 792180
gtaactgcaa caattttcat attcatttcc tcctataatt gttcattgat tgcatttaat 792240
gcacgatatg catcttcaac atcttctact tcaatcaatt gctttctaaa attatcatct 792300
aaaagtcttc tacttaataa agaaataaat ttaagatgaa tattattttg attatcttgg 792360
ggcacgccta taaggaaaat caattggact gattgtttct catcatgatt ccaatgaaat 792420
gcatccttta tttgaacaaa tccaataaaa gcacgattaa cagtatgact aattccatga 792480
ggaattgcaa tttggtaacc aattgaagtt gaagccattt cttctcgttt ataaaccgct 792540
tctttaaaat cttttttact attaattaaa tctagtttaa tagcctgatc tgataataat 792600
tcaataacat catctttagt cgataaagct tgctttaaga agaccatttc cttatgaatt 792660
gctttttcct gcataatcat tccccttatc cttttttaca agcaagcatc tttgatgtta 792720
atccttccat attaaaacat ctaacatgtt tttgcatttc ttcttttagt ttttcaataa 792780
caaatctttt tccatcaatt ttaatgcttg ctaagttttc atataattta ttaatttcta 792840
atgctacttt aggtttagaa taagtataat gaccgcataa ttctgtaatt tgtaatgttg 792900
tttgctcatc taaattatct aaatccgaca tatctacttc atcagtaagc cattttttcc 792960
atttcattga atgaattgat tcatacttaa taacattttc taaatttgat ggctctttaa 793020
tcatattaaa tttagcaaac tgtttttcta cttcaattaa ctctaataaa gccatcgttt 793080
caatcgttcc aaaagctgga gcaacattca ttgctgtgat atttaaaggt aaatgtgcta 793140
gtaatttagc ttcacttaaa taatcaccat tatgttcctt taatcctact ccatatttag 793200
ttgatattgc acttaattct aaagaatttt cataactgaa attcccaaca tttttagtta 793260
aacgtgttaa cgttccagtt tgaccaacga taaaaattgg cattggtaaa tcatgttctt 793320
gagtataaga ttcaattctt tggataaaat tttcatagcg atccatcgaa gttaaaccac 793380
cacttgtttc ttctgtccct acttcatatg caatttcacg ttcaattcca tattcttttc 793440
taacttgctc acaatactca attaattcta tagtacgatt aaagacaaca tctatatcca 793500
ctactttaca atattcatca ggatccttag ttggatcaat atgtaataaa tcaaaaccat 793560
ttaaaatatc ttctttatat gactctttgg caattgccat agcttcatct tccggtaaat 793620
gatctgctct ttctttatct ctttgccatg gtccaccatg atcacggcat aaataataga 793680
cattatcata attaatttct tgcgcaatct cttcgatttt ttctttgaat aacttttgat 793740
cactgttgaa tacatatcca ccaccaaatt tatatgcatc aacttgatta cgacttgcaa 793800
tatacattaa tggaaaatct ttttcttttg aaatttctaa agatgcccgt aaaaaatttt 793860
cagacatagg tccaatccca agtaatgtat gtttttctcc ttttgaatta attacataat 793920
taactgcttc tctaattgta acttttttat tcatttttat cttctcctca tcatttagca 793980
attaatcaaa tgtcgacttt tgatttatga gataggtatt tgtttctatc tacacatata 794040
tcatattcaa ttagtcacaa tgacataaga taaaacaaat gaaagaaaaa gttacaaaaa 794100
ttgcacccta ttgttgatta agaaaaaata gaatttaaac tcaactagag cataaattct 794160
atttttttaa atcagcatcg ctgctaataa taaataatta atttttcttc atataaaact 794220
actatctttt aatcttgatg acataataat agcgtaccta ataacatata ttcttggaga 794280
taatcaatta aaacaatttc aggaatataa tctttaggaa tatatttagc tacctctttt 794340
ttcaattctt caatattagt aattaaaaaa caacatataa caataatttg cggatctaaa 794400
aaactgatta ttgatgtaac agttttagcc attgcttcaa tggctccttc tggtgtttga 794460
tgtaattcta aaacatcttt tgaatatgat aatggcaaat attgtatttc tccagctaca 794520
tgatggtgtc cagcaatcaa acgatcattt acaatatgtc ctgcccctga gttcgaacta 794580
accggttgaa aaacaaatga cagtgatgaa cagttttctt tagaactata atagcctaaa 794640
gcaattgtat tagcatcatt actaaaaaca aatttttgcg aatatttcaa agtaaaatca 794700
tgagtaattg aaattttctc tagccccttt atactcattg agataatctg atcaccacgt 794760
ataattcccg gagtcgataa tccaataact ttaatatcta catatttagc cagcatgcta 794820
tcgattacat cataataatc ttggattgat aaagtaggtt tgataatttc attattttct 794880
aaaatactat tattttcatc atataaacgg tacacaatat gaacacgatt actattccta 794940
attaaagcaa gacacaatgt tttaacacca ctaggctgca tatttttagc tttcaacggt 795000
ttatgcattc cttttgccaa ggttcgttta taattacgct cctcttcaat aatcgataac 795060
atctttttta catcatattt agcaaatata gcaggcggga tatttaaaac gattttattt 795120
tttaaaatct cacatacctt tgcatacata tatgagattt gtggtgccaa cataatcatg 795180
tcataatctt cactagcctt ataaagatta ttatagctaa ccgcagacac ttgaacatcg 795240
atattaagta actttgttat ttgattgatc cgatcagcaa aataacctgt cgttaaccca 795300
ccagtacaac aaagtaaaac ttttaaagct ggtttatttg ttaattgctt gatcgtttct 795360
aacatttcat caaataattg aattgcatgt ttgatatttt taatttggaa atggagataa 795420
aattcaactt ctttttttat taaattttca accgaaaatt caactatatt catattataa 795480
aaattaacct ggctagtact atatttattc ttaatagcaa tcgttttata atcatccgat 795540
agacttatag ctaaattttt attactttgc attaagatcc actgtttaaa tacctctata 795600
taaatttcac tcaagaattc atccattttt tcactccttt atcttctaat gattttaata 795660
gtccctgatt atacatacct ttattatatt ataaaattca tagaaaagag accaattgcc 795720
gttattctga taataatttt tcaatttaat ataaaaaaag gataaaaaga aataaatttc 795780
tttttaatct ccaatttaat ctttataaaa atcataatta aacattaatt ttggcaacta 795840
ttaaaagaaa caaagctacc gccttgtttc tctttattcc tacataaccg tgataatcga 795900
ctttccagcc gttactttac catatttttc taattttaat gtttttcctt tagtatctag 795960
aaaaacaatc ataattgtat agtcaatatt ttcatttctt aaataattaa gatctagttt 796020
aataattttt tcaccagctc caactttttg atttttcttt tttaatattg taaatccttt 796080
tccttttaaa ttaacggtat ctagtccaat atgaaccaag atttcaacac cgtcatctcg 796140
tgtaattcca aaagcatgac cagtaggaaa taatgtcgtt aatactcctg cgcaaggggc 796200
acagacctct gacgaggtcg gaacaatagc aaccccttct cccattactt tttttgaaaa 796260
tacattgtca tcaacatatt caagattaaa actgactcca tttacaactg catatacatt 796320
atttgtattt ttttgattat tttttaatga tttaaatatc tttatcatag tattaactcc 796380
taaatttgct aatgactatt ttgttggaag tttttatttt ttactggaac atcttcaaat 796440
cctgagaaat aactcaccac actagataca acaaatgccg caataattgc gataatgacg 796500
ccaataatcg tttccccata aataggaagt gccaaaatac taggattacc ataagcaaat 796560
gcctttactc caaaaaatcc agcaatacaa ccgccaactg caccaccagc cataacacca 796620
tacattggct tttttagacg cagattgatt ccgtagatag ccggctctga taccccggct 796680
agaatagccc cgacaccact actaatcgct tgtgaacgta attctggatt cttagttttt 796740
agtgctaccc caaaacaagc tcctccctca gcaacattat gaacaaattg tgttggcctt 796800
aaaaaacctt cataacctaa tgatgcaata ctttgcatca ttacagggcc aaaaacagta 796860
tgcattcctg acattattac aaatggcaat acaccaccga gagctccaag cgcaaatgga 796920
ccaatcgtgc tttgcatcca aactaagaaa ttaataaaat attcaccagc aaaaaaacca 796980
attgggccta atacagtaag ggttaaaaga cttgcaagaa caagtgttaa tccaccaaca 797040
aaaattcctt taaacattcc cggtaaatac ttattcaaaa gcttttcaat atttgcaact 797100
gctacagttg ataatattgc tggtaaaaaa gatgaagcat aacttgctga ataagctgtg 797160
aagcctaata tttttaaggg ctcttcagca cttaacatcc caataatatc tggatggatc 797220
agtagacaag ctactatcat tgaataaata ggtgtacttc ctaatctgat tgctgcaccg 797280
tatgctacaa aaacaggcat aaagtagaaa gaagtattaa caataccatt tataactaga 797340
tatgtttgat tatcaacaat ttccggccac gctaatgagg ttagtaccaa aaatactttt 797400
attaatccag ctacagtaag cccaggaatc attggtgtaa cacatgcaga taagaaattg 797460
aaaatatttt ttattcctct tttccaaatt ggcgaatcat ctttttcttt aatatcttca 797520
tccaaaattt catcaataat ttctgctact tcaaaattat aatttttaac tacttgagta 797580
aatgtcgcag ataaattttt ccccataatt atttgaaatt gaccggcacc aaaggttgag 797640
cccaatactc catcaatttc attaatctta tcttgattaa ctagattttt attttttaat 797700
acaaatcgta atcttgtaac acagtgggtt acatatttaa cattatcctg tccgccaatc 797760
gctataatga tttgatcggc tatttcttta taatccatat tattctcctc tatattattc 797820
ttgaaatatg tactaataaa taaaatcgtt ccgcctctga tagtacataa tcaaattctt 797880
catttaaata tctttcgatt gaatctaacg taatacctat ttttttatta atatctgact 797940
tagcacttat tattaatttt tcaaaattct catcatcact ttcacccttt atcacccgct 798000
gcataaaaaa tttaagatga atcactagcc tagagtaata cagtgaatct tccggtagtt 798060
caagaccaaa attagcttca attatattta aaatatcatc tatgctcttt aaaatactcg 798120
ttgttttgct tacattatta ttaaactcag cattaattaa gtgaaatgct atagcacttg 798180
cctctttttt atttaaattt atttgataat atctattaat caaatctaat gctttaaggc 798240
cgacttcata ttcttcatga tagaatcttt ttatttcttc actaactaaa ctataactac 798300
cataaccctt tagataattt ttggaaacaa agttaatatg gtctgatagc gatactaata 798360
atccttgatt aaaatttcta tttaaatcag tttttgccat atctataatt tcttgggtca 798420
attcaataca tttaaatgga atttcattca gtaaggcttt aaattgaatt ttcaataaat 798480
tattttgtaa cgtataaagc ttgtaatttt ctttcattgt tatataatca ttaactttat 798540
gattaaatcc tacgccatta ccaataataa ttatttctgt tccattttct aatatttcaa 798600
tggcattatt atttaagatt ttattaattc tatagtattt atttttcata tctaatcctc 798660
tacatttatt aaaatgttaa atcagacccg tttgttttaa ttaccttctt ataccaataa 798720
aatgaatctt ttctataacg ctgtaatgat ccttgtccat aatcattcat atcaacatat 798780
ataaaaccat agcgtttctt catttgtcca ctagctaaag atattagatc tgtacatccc 798840
cacatagtgt atccaaaaca tggtacttta tcaatgacaa tagcatctct caattgtttt 798900
aaatgttcag ccacatattt tattctgtaa taatcatgaa tttttccatt ttctaaaata 798960
tctactgctc ccattccatt ttcaataaca aataatggtt tttgataacg atcataaatt 799020
tcatttaaac aatagcgtat acctaatgga tctattcctg caccccattg ggtctttttt 799080
aaatacggat tgggttcccc acccatatga tcaactttag aaccagcact aacaattgaa 799140
gaacgataat aactaaatga aataaaatct aaagtatgtt ttttaatcaa gtttcgatct 799200
tcctcactta ctttcaattt gacatctttc ttattaaaaa tatcttttgt ataatttgga 799260
tatgacccgc gagccattac atcaacgaaa aataatgctt cacgttgctt acaataagtg 799320
gcaaaaacat cttcaggatt acatgtagct ggataaattt cgcttaatgc aaacattgct 799380
ccgaatttta tgtctcccat aattttcttt ccctgactaa ttgctttagc acttgctaca 799440
aacatatgat gaactgcttg atatctcgtc tgactatctt gtctatgggt tcccatttga 799500
gcgtacccac ctaaattatt tatttcatta aaagtaatcc aatatcttac tttatcttta 799560
aatcggttaa atagtgttgt tgcataattt acatagcatc caatcgtttc tcgccccgcc 799620
caaccatcat ataattcaca taaatgaaag ggtacttcat catgacaaat tgtaatcatt 799680
ggttcgatat tatattttaa aagttcatca attatcattt cataaaattt caaaccatct 799740
tcatttgctt tttcttcatc accatttgga aaaattcgac tccatgaaat agaaaaacga 799800
taaactttaa atcccatttc tgcaaacaaa gcaatatctt ctttccaatg atgatagaaa 799860
tcagtcgctt gatggctcgg ataatatata tcatcataaa tatacggtat agctccatcg 799920
ggaattgagt ctcgataatc aatactccct ctcgttccat tatttaattt taaagtaatt 799980
tgtctttctt tatctatgtc accagcagtt tcaaaatcat gactcgataa gcctcttcct 800040
ttttctttat atccaccttc atattgaaaa caggctgtag cacctcccca taaaaaatct 800100
tttggaaacc tgatcatttt cttacctctc ttcctctcta atttgccaat ataaaaaggg 800160
caataccaaa aagaagctaa attctttttt ggtattgccc cttgtttttc ccgggtaaca 800220
agccatattt aattgacact tatattttat catataattt attttttgca agggctttca 800280
aaaaataaaa ctatttacaa tattttgctt attaaaagta aaagcacaaa cacataggta 800340
aagagactaa gtaaaacagc tccaatgtat ctaattatca aaataccagt gagagtaaat 800400
atgccttttt tgaatttgga atttctatcc tcataatcat tagaataaag tcaatcaaat 800460
aaatatctaa agctattgat gaaaacaatg ttttaaaaag atttgattct aaaatgattt 800520
tctccattta caacatagtc acttatcaca tagatgctac cagcaccatg aagattgctc 800580
caatattaaa agtacttaaa taagttattg tcaaagatgg cattatcgct tgaacaaacg 800640
gcaaaacaaa gcttccaatg ttatatacag aagcatttaa catagagaca cctttcattg 800700
ttttggaatc tcttaattta acatgatagc caacaaccgc cataattata ttatttaaaa 800760
tttctagaat aataaaaagc atgatatttg atgtcaatcg aatctcacgg ttcccgcaag 800820
caatgtccat ggacatgtaa tgtttgttat aagtaaagca agaacatacg aatcactttc 800880
tttaatatat cctcttaatt ttataaaaca tgctaaaaag ataatcaaaa taaataccat 800940
tgcttgttgt attactgacg tcataaattt ttatcttcta ttcttttgta attactatgc 801000
ttatacttga tgtatcgatt ttaataattc aatacccgtt tttgttttaa atattttttc 801060
cataaaattt cttatatctt caacggaata attgctgctg tttcaagagc ttttaagtct 801120
tgctgattca gttttactaa ttcaccaatg ttttagcata agcatgcact tttaagaaat 801180
gtttaatgtt atagttattt ccattagcat atttaatcat tttatttgca atattataaa 801240
tcatcacaat ccttcttaat ctaataatta atcctaataa aagaataatc ttcatatcta 801300
ttaaaataaa gattttttat attctcactt attttcatta tttaataaaa aaagcgcaac 801360
taaattacgc tctaaacttt tatatttttg atagcagtac gattgtctca acatggctag 801420
tatgagggaa catgtcaacc ggatacatta cctcaccacg atagccaatt tttgcaaaat 801480
acttgatgtc ccttacctga gtacttggat cacaagaaat ataaacaact tgtttaggat 801540
tcaagatttt tacagcatcc ataaattcct gcgtactgcc actgcgtggg ggatccataa 801600
ttacacaatc aactttttgc ttctgtttag ctaatttaat cataaaagca gaagcatcat 801660
cattaataaa tttaatattt tcaatcttat tcattttagc attattgatg gcatctttaa 801720
ctgcatcttt atttaattcc acaccagtaa cttccttagt tctattagct acaatcattc 801780
caattgtccc aattccacaa taagcatcta taattctttc ttgacctgtt aaattcaata 801840
aatctagagc tttagaatac agtaattcac actgttgatg attaatttga taaaatgatt 801900
ttggcgaaat cttaaacttc aaaccacaca attcatcaac tataaatccc ttaccataaa 801960
gaatcttttc ttcattacct aaaaccacac tcgttttacg tttatttaca tttaatacaa 802020
ccgtcttaat acttggaaaa tttttaatca actcattaca aaaatttttg gatcctttaa 802080
atacattatc attgcaaact agtactacca ttgtctgatt agtaacaaga gcacgtcgaa 802140
ttaatacatg acgcaataat ccgcgattac gattttcatc ataaatacta actcgatatc 802200
gttttaataa gctttgaatc ttcttaataa tcatatcact gagttcttca tgaagaagac 802260
aacgatcata aggaataatc ttatgactat cctcttcata aaagccaaat tcatatctat 802320
gattaaaagc aacaattatt ttattacggt attcataagg atgccccatt ccaatagtat 802380
ccttgacttc atacatgtct aatttattat cttttaacag cttcttacaa taatctgttt 802440
taatctttaa ttgtctctgg taatcagtat taatgtattt acagctacca catttcttct 802500
ctattaaaca tttcatttta tcacctagca acagtataac ataactaaag caaaatacta 802560
atcaattcct tctctcatta ttatttcttc ataaataaaa acaaggtata gtttgttacc 802620
aaactatacc tactattaat cttcagatat ctcttcttca atgtgcccca ctacttgaaa 802680
tgacttatca gtatactgca taatttcaaa tttattacca tcaggatcat gcacccacat 802740
ttgataggta tgtgatggac ctttagaaat aggtgtatct attgcaactc cacattcaac 802800
tagttctcga taagtttttt ctatatcctc aaccaataac gcaaagtgtg aataccccag 802860
cctctggttc cactcatcat gtggcgcttg tccttcatcc tttggaaata gttcaataaa 802920
ctgtccaggg gcaatttcaa tataaacaat gataattctg tttggatcaa cttcagctac 802980
ttcactatat ttaccacgat ttagtccttt ataaagtccc gcccttgtta caattttaac 803040
ttttaatcct aacttatttt cataaaagtc tctcatcaca tccatttgat cagtgaaaaa 803100
agatacatgc atcaagcttt taaattccat ttgtcttctc ctttaattat catttgtaaa 803160
tactattttt tcttgatttc ttgcctcatt catgacttta gctactatta aacttaattc 803220
cagcatcttt ttagcaaaat cataatcatt attatcaatg attctaataa attcaataaa 803280
ttcataatat aagcgatgtt cacaatcatc aactcgataa atttcttcag tgccatcgtt 803340
aaaaataatt tgatatccgg tcatctgatt aacaggttta tcaattttaa taaccccttt 803400
atcaccttga atcgttgaaa taatcggtgc tttgcaatct ttagccccta tacttatccc 803460
cttaaacgaa ccataatcgt acattagaat accacttgta tcaatttgat tctcaatatt 803520
tgccatatac ccaatactta ctggttgacc aaataaactt attattgcat taacattata 803580
aacattgata tccatcaaag ctccacctga tttatgataa tcaaatgccg gtaaaattgt 803640
tccttgttta aaagcatcat atcgtgaaga atattgacta taattaaaat tcatgatttt 803700
aatatttcca attctcttta tatcttcttt caatttttta aaagcaggta aataatggat 803760
attaactgct tctaaaataa ttagatcgtt ttcttgagca atttctttta attcttccaa 803820
ttccttaaca tttgaagtaa taggtttttc cattattaca tgcttacctt ttaataaagc 803880
ttttttagca aaactaaaat gtaaatgatt tggcaaggca acatacactg tatcgatttc 803940
acttcgcaac atttcatcat agtcataata acaatgatct agatgatatt gcttagcgag 804000
aatagtagtc tctttcttag tttgttcagt ccctaaaatc gaaattgatt caatctttaa 804060
cttatttata gttgttaata agtctttaac aatcatccct gttcctaaaa tacctaattt 804120
catttaattt gcctccctaa ttatttctgt taattccaat atcctttttg tatcttccaa 804180
actatgaagt gcactctcag ttttatgagc tcgtacatca tcaataaagc actgaatctc 804240
catagtcata tcatctccaa taattggata attgcgttca accacagtac catcattttt 804300
tatgatttta taatcaataa tacgattaaa cattggaatc tctatttttc caaattcacc 804360
ttcgataatt gctaaacgct ctttattacg atcaattgcc ccttccacaa tcgcagtaca 804420
ttcattatta aaattaattt ttgctttaaa ataccattca actccagcaa caatatcaat 804480
ctgtgaatta acattcttta tatctgaatc caccaaagct aatacaaaac caagcaaata 804540
acttcctacg tcattcagtg ccccaccttg atcaacgtta aataaatatg aggtagtttg 804600
gtgagcagta gcatcaaaac aaaaattagc ttcaatttgt ttgattttac caatcaatga 804660
taaatcctgt tttaaatgtt ctaaaccaat attaaattta gtctttaatg cttctaagca 804720
atatcctttt tccgtatata cttttgtttt aatctcctca atatctgcaa ctgtcaatac 804780
cattggtttt tctgataata ccgcaatatg attatcaagt gcttttaaga tccattcctt 804840
atgatattta tgaggtaagg caatgtatac agcatcaagt tctcgatcct gtaataattc 804900
gtcataatct tgatatattt taacttctgg gtgagctttt acatattcat catcacttgt 804960
taaggaatga gatgcaattg cataaatctt tccttcgtca gtgtattcaa tacttttaac 805020
aaattttctt gcaatattcc caaatccaat aattccaaaa ttcattgatt ttgcctcctt 805080
ttccttgtta taacataact atttattatt taaatatatt tataatattc tggaaacaaa 805140
gtactaagaa aataaaaaaa atactgtgat ttttgtactt ttagtacaat cacaatactt 805200
ttatataacc gtcataatat aattgaccca taaccagcta attggcataa caataaccat 805260
tgcaggaatc atatccgcaa ttggaaattc tttaaccttg atcattctaa atcctgtagc 805320
aatcattaaa aagccaccac aagctttaaa atcattgatc attgctggtg tagtcaatgg 805380
aaaaataaac tttgctgata aaaataaaat aaaaaagatt acaaactgcg gaatggcaat 805440
tacagatacc acatacccta aattacaagc aaaaatcaca gcagtaaaaa aatcaagaat 805500
tgatttagaa atcaaaactc cattatcacc cgtcattcct gaagttaagg agccataaat 805560
tcctgttcca ctagcacaaa ataacacaat aatagtaatt aaagtagatt gaaactcttc 805620
cgaacttaaa tcactaccat tatttttaaa tattttggca attggctttt gcattaaaat 805680
tgctccctta ttgatccaat cactaaagtg cagtgataat cccacaatag ttccaataat 805740
tattgaaaag attactgccg gcatattttc cattaatcca attgcattga ttcccatagc 805800
catagcacaa atcccaaaaa tcaaggttat ttctgtctta agtctatgac ttaatttatg 805860
acctaataat gcaccaaata ttccccctaa tacaattgat aaactattaa taatgactcc 805920
tgttggcatt atttttcccc ctttataatt tgaaaattat ttctctaaaa gattccattc 805980
actctcttta taaagaatat catttttatt agataattgc caattaaaat agtttcttgt 806040
cttattaaga aaaaaaagga cataattcta taggctacaa tatttgaacc ataaaataca 806100
tgatgttata atataaagac aaaaaggaga tgaactatat gacaaaagta gatattatat 806160
ctggtttcct tggagctggt aaaactacat tcataaaaaa attaattagt gatgtatatc 806220
caggagaaca aattgtctta attgaaaatg aatttggtga aattggaatt gatggaactt 806280
ttatgaataa tgctggaatt gaagtaactg aaattaattc agggtgtatt tgttgcagtc 806340
tagttggtga ctttgaagct tcattaaaag aagtattaga aacatatcat cctgatcgaa 806400
ttatcatcga accttctggt gttggaaaat tgtcagatgt aattaaagct gttagtgatg 806460
tacatagtca tgaattagaa cttgataatt atattgctgt tatcgatgct aaaaaatgtc 806520
gattatacac aaagaatttt ggagagtttt ttaataatca aatcgagtac gcctcactta 806580
ttattttaag ccgaactcaa gatataacag aatttcagct agatgagtgt ttaaaaatta 806640
ttaaagaaca taataatcaa gctaatgtca ttacaacccc atgggatcag cttaccaaag 806700
aaatactaac taatgccttt agtaatagtg ataatcttcg tgatgaattg ttggaacaat 806760
tagatatttg tcctatatgt gcccatcatc atgatcatca ccacgatcat gaacatcatc 806820
ataatcacga acatcatcat aatcacgaac atcatcatga tcataattgt gagtgtggtc 806880
atgagcacca tcatgctgat gaagttttca ccagttgggg taaacagaca cctaaaaaat 806940
attctaaatc tcaattagaa aaaatcttaa aagaactaag tgacagttcc gcctatggaa 807000
atattttaag agctaaagga tatgtcgata gtattgaagg tgattggtgg tattttgatt 807060
tagtccctgg agaatatgaa attcgtatag gaaaacctga ctttacaggt cgaatttgtg 807120
tcattggcga aaaattagat aaaataaaat tagatagatt attcgatgag gtcgcttaat 807180
ggaaacaaga gtatatattt tcgcaggctt tctagatagt ggtaaaacct catttattaa 807240
tgatacttta atgaatcctg atttttatag tgaagaagac accttattaa ttagttttga 807300
agaaggtgaa gttgcctata atgatattta tttaaaaaaa tctaatactt cattggtaac 807360
attagatttt gaaaatttta ccacctatga tctaaaacat ttagaattag aatatcgtcc 807420
tactcaaatc atgattgaag ctaatggaat gatggacctg aatatttttg taaaagaaac 807480
gattcctgaa aactggaaag tggtccaagt attaacaact tttgatacta ctactttttc 807540
aatgtattta aataatatgc gttctcttgt atatagtcag gttgtcttta gtgatcttgt 807600
tatttttaat cgctacgatc caaatattag aaaatccatg ttaagaaata atattaaagc 807660
gattaacagt aatgctcaaa tcatttatga attagctaac ggcactatag atacaatgaa 807720
tcctgaagaa gaattaccat ttgatattaa taaagaacat ttagatatac aagatcatga 807780
ttttggaatc ttttgtatgg acgctatgga tcatcctgat aaatataatg gtaaaacagt 807840
caaaattaaa ggtaagttta tcggtctaga tcgtgtcatt gaagatggtt ttgtcctagg 807900
gcgtcaagct atggtatgct gtgaagaaga tacctcattg attgggcttg tctgtattag 807960
taagctagca aataaattga ttcctgaaga atggatcgtt gttgaaggaa aaattacagt 808020
tgattatgat ccggaatatc aaatgaatgt tcctatatta acagtggagc acctcgatgt 808080
agtccctcca ttaaaaaacc aatatgtgac atttgattaa aaataaagat gcctgcttta 808140
ttataaaaaa gcagacatct ttattatttt ccgagttttt caactatttg aactactaat 808200
tcttgaccat tcatctgacc ataaacgaat ggatcaatta cttcgatcgg tttttctggc 808260
aataattcct taactcgata caaatcatgt tttatttgag gagcaataaa aatataatca 808320
gcatatttcc ccaattcatt aatttttaag attggataag catatacttc ataattatac 808380
ccctcttgac taatatacct tttcatacaa ttaactaaaa tacttgttga aactccctgt 808440
gcacaaaaga tatatatccg cttcattatt cagcctgcaa attattttct tcatcaagac 808500
atttcttatc gtatactttg atgaatggat accaaataag gccagataca atgaacatta 808560
caacaaagat aagcaccgca cgccaatcta aagtacacaa gtattggaaa aacggcatcg 808620
gaatattaga actagcagca attacagctt tacccataat gccaaaattc atacagcacc 808680
aaattattcc catattgatt gtgtaaaaag caatccatgg aattcctaaa attggattaa 808740
acataattgg agctccatat tgaattggtt ccgcaatatt aaaaattgct ggaacaatcg 808800
atattttccc cattgatctt aatcgctcac ttttacattt taagaataat agaggaatta 808860
tgtaacaaaa tactccagac atttggaaca ttggtaaagt gaatattttt gtagcagttt 808920
ctccggctgc ataagcagca gcattagcac ctgtattggc aatcaataac ggaagaatta 808980
ttccagatac aacattaaac ccatgtactc ccaagaattg taaaaatgca ataataaatg 809040
ccatcaacat acagaaccat aatgattcag aaccttgaat cgccggtgtt aataaactca 809100
ttatccaaga tggtaatagc atccctgtaa aattttgaca aagtaaagat aatccataga 809160
aaccagcaac gatcaagcac atcggaataa tcgcatcaaa tgaagcagct actgctggag 809220
gaacactatc aggtaattta atttgaatat tacgtctctt tagtaattgc atgatttcca 809280
cggttaccaa agcaacaaaa attgctaaaa agattccttg tgatcctaga taagttgcat 809340
ccatattatt atcaacaatt ggtgctgcca aaacaataaa tgataacagc gatacaatcg 809400
gcgcttgtaa taaatcaagt ttatatgttc gtgcatggta ataagcgata gcgcatactg 809460
caatgactcc aaataaaccg aaaaccatat tatacgggaa taaaattgca tcctttatcg 809520
tctcactata actaggtatg aatggaaata tatctggtaa tgctgaaata agctggaaaa 809580
tactcccaaa aatcgttaat ggcattattg ccattaatcc aaaactaatc gattgcaaat 809640
gcctttgtgt tgctaactta ttgcccactt caataagttt atcttgtaat tttttcattt 809700
tattttcctc ctatatattt gctgcaataa aatacgcatc attagttgct ccaactactt 809760
gtcctaactt ttcacaatca ccaaacatca tcgtttcatc agctattcca tacaatttaa 809820
aagcttcctc acgatttggt ttcattccaa cagcaattat ggcattatca catttaataa 809880
tagattcgcc atttttattt attattttaa ctccgctttc actaaatcct aagcattgac 809940
tatttattaa aatggtcaac tgtttttcaa atcgttttaa caaacgcctt aatcctgctc 810000
gatataaaat atgcccttga ctagctattt ggtcagtcat ttctattact gttactaatt 810060
ttccacgttc taataactct actgctaact ctattccaac ttgtcctccg ccgacaatac 810120
aaacattatc ttttaaagaa tccaatttag gataaatgtt ttcaaaataa tcaacatatt 810180
ctaattgttc ccctgggaaa tggaggcgaa ttggtgaagc tccaatggca acaagcacca 810240
catcaccatt tagttgctct aataaatttt tagtagcggt cgttttatac ataacttgaa 810300
tatctcgctt gttaatttgg ttttctagat aatctcgata tgcttttaat tcctgtttat 810360
gcatttcatg ttgggccaaa tttaattgtc cccccaattt atcacgttgt tcaatcaaaa 810420
taacttgatg tccccgatca tgtgcagtta ttgcagcttt acaaccagca ggaccaccac 810480
caacgacaat cactttttta ataatctcac ttttttctaa ctttaatggt acccgatgtt 810540
cccgacgata tcgagggttt acagagcatt gtacatttgt atgttctgta gcactatgat 810600
agcattgtaa acagcgaata catggtacaa tatcatcgct ttgcccctgc attgcctttc 810660
gtggtaaaaa tggatctgcg actagaggtc tacccattga aataatatca actacacctt 810720
cttgtaataa ttgctcagct tcttttggcg tcattattga accaattaca ccgactagtt 810780
tattaggaaa gttttgttta actaattttg cccaatgaac attagttaga tgcggttcaa 810840
aaatactttg acaatgtttc ccattaacac tataccaagc ttccaatcct aattcaggct 810900
ctattatttg atcttctgga aaatatcctg gaatcatatc catcccagct gatacattga 810960
tcaaatcaac atcatcttcg attcttttta ataattccaa catttcttca aattgataag 811020
acccttttaa ataatcactc gctcctaaca atataacaat tggaaagtct gtgccaacag 811080
cattacgaat cgttttaacg tgctctattg taaagcgcat acgattttct agcgaacccc 811140
catattcatc tgttctttta ttaaatactg gagataaaaa ctgggttgtt aattcttcat 811200
atccaacgta caaatagata aaatcaaaac caaatcgttt gattgccaat gcatcatttc 811260
ttgcctgttt cataattccc tgaatatctt caagcgttaa ttcaactgca cgagcgccac 811320
ttcttgttaa atatggtgat ggtgctaaaa cctgcttacc atcataatga gctcgaatat 811380
cattagctgc atcttgtttt agtcgtggta cacaccaagt tccaacctta gccccatact 811440
gacgggctac tgaaatagat tcacgaatac catcgcgatc atgttttgga aattcaccat 811500
tggcattagc cgcagattca attgatacaa aagtcattgc tgctccacct acagacttat 811560
ctataatact aacatttcca tagtgagtcg tagataataa ttcatggctc ttgggaatcc 811620
ccatcgttga tgcaataatt ctatttttca acatcattgt attaactctt aatggttgaa 811680
ataaatgtgg ataatactga ttcattttct aactcctcct tgctctctta ttgtatgtca 811740
aatagctttt gcatccaaac cagcttttgc cacgatcatg gcaaaagctg aatcacaatt 811800
ttaagatttc tatcaagaag tttgttataa tatgataaag gagtgattat tttgcttgaa 811860
cttacctcta gacaattttt aattattcgt ctattacaaa aaaataccgt tccactaagt 811920
gctaatacgc tatcaagatt actagatatt agtcctagaa cacttagaaa cgatattttt 811980
caaattaata aaaatattga ggattttcat atttcttcat ccaaaaatgg ctatcaatta 812040
actttattaa gcgaaaatgc ccatatgctt ataaatgata ttaaaatatc cgaacaatca 812100
aagtctacca atataatttt acaatatctg cttaatcacc catcatgtca cttattagag 812160
ttatcagaaa attgttatat gagtgaatcc agtgttgctc gctgtattaa aacaatcaaa 812220
ccgcttttaa acaaatatca tctaacagtt gaacgaaaaa atgatatttt ttcgttacat 812280
ggtagtgaat atgataaaag agctcttttt gctcatttaa ttgggattga agcttcacaa 812340
ccaataacta gcctacaaca ctttcaacag tattttcaag attttcatct ttctgaagta 812400
gaagctataa tcgactctgt tttaaagaaa tataatattc gagttgacga tattcactat 812460
caaaatcttg tgatgaatac atctatcacg cttcaaagaa tttttgttgg aagcgacatc 812520
gaacccctgc cgttttcata ctccttatca aatgacgaaa ttatttgcca gctgtccaaa 812580
gacctatgtc ataacctaga agaatatttt aatcttcatt ttgctcaaac agataatgaa 812640
tatatgcaag tcctttgtat tggctcgatt aaaataaacg aagaaaatta tgaaacccaa 812700
attttatata atgattatag ttttgtttat aaaattaaag aaattctcga tgatcttgtt 812760
gaacactttt cattgcaact taattatcaa atgtctttaa atcattttgc tttacatatt 812820
catcgtttat tttttagaaa tcattcttcg ctttactttc aaaatgactt ccataataac 812880
cttaaaaata cccatccttt catttatgag ttagctgttt attttgccta taaatttcaa 812940
gaaagtttca atattacagt gaatattaac gaaattggcc tattggcaat tcatttaggt 813000
ttaatgattc aatccaatga agaaaataaa caatatttaa aagcactatg tatttgtcca 813060
gagtataatg atttacgaaa gcattttgcc aatcaatttt tattaaactt tggtgataat 813120
gtacaattaa ttagttttat ttcttctaaa aagaatattc aagactatca ttttgatttt 813180
ttgatttcta ctattaatga ctatgaaagc cccgattgta tggtaatcag ccccttgcta 813240
ttatcacaag atattgataa attgaatctt aaaatcaatc tattaaaaga gaaaaagaaa 813300
aaagatctgc taaaaaagga attatctaaa tacattgatc ctaaactctt ttttagaaat 813360
gttgatttta catgtaaaaa ggatgctatt ttatttttat gcagtcaaat gttaaaacat 813420
ggtgatgcta aaacagattt tgttgatagt gtatttgaac gcgaaaaaat atcaacaact 813480
tcatttttta ataaatttgc agttcctcat gcaattcatt ttggtgatgt aaaaacccga 813540
attacttttt tattgaatga caaagcaatt ccttggggtg atacctccgt tcatttagtc 813600
atgcttattt caataaatga aaaagacata atgactttca atacaatcta ttcttcaatt 813660
attgatcttt tattagatga tgagtctttt gatgaaatgt tgaaaatcaa aacatttgat 813720
gaattatcag tttatttaga aaatcatgtt taaaaaagtt gtaatgcttt attcattaca 813780
actttttaat ctttatgcaa agatatttca tttattaaaa tattatgttc ccgatgattt 813840
gaatccacaa aattaactgt accattttca ttcaacttag taaatgtaac taaaccataa 813900
tcttgaaatt caacctgttt atcctttaaa taagcaatat cattagcata atcaagaatt 813960
ttatcatacg aaccttgctg ataaagacta tagtatatct taaaatatgt taacattgct 814020
atcattagtg atttaacttg atatgtctgg ccagttttca tcttcattga agcataatca 814080
ccgtttattg aattaacatt taatccaact ccaactacaa ccccttctaa atcagtttga 814140
tagattgcct ctactaagat tccacaaatc tttaaatcat caacataaat atcattgggc 814200
cacttaattt tagcttttat tccataacga tctagtaacc ccgccacact acaagcaact 814260
agctgtgtca ttttatgaag gtcttgaggt tttttaaaat cttttaccaa aatactcatc 814320
agcaagtcat caccattctt actttgccaa acgtgtccat tccgaccccg accatttgtt 814380
tgataattac aacgaactac acttagatta ggaagtttat ttaaattacg ttttacgtaa 814440
tcatttgtag aatcgacttc gtctaattca atataactca taatatcacc ccattactat 814500
acttctatta tattagaaat ttaggaaaac aacaaatatt tattataaag ttttattcta 814560
atgcaccctt tacttttttt ctagtgaaac aacgatcttg acgattagct aaagcgctaa 814620
cccgggcttc tagcagtatt tttctaccac tttcattacg agtataaata acctgataat 814680
taccaataaa cggcttcata tagccagcaa atatatgcgc atcttctttt cttttagcaa 814740
aactatcagg aattgcaaaa taacaatcta atttattttt tcgtttagga ttataaagaa 814800
tataacgttg attatcaata gatgcaaaaa attcattgat gcatttggca aacaaagcct 814860
tatcatgccc tgttccccct aataaatata ttgcatgtat cgcattaaaa gaatctgttt 814920
caacgcgact attcaaagaa tccagctgat tggttttttc taacgcattt ctaattcctt 814980
tgccaaatat ttctaaacga cctaaaggat ttgctaatgt ataaagtttt ttgatgctca 815040
aaagaatact cataacaaat attccaacat aaattatcac cactagatat tctaaaatat 815100
ctatcaaggt caatgatttt agaaatggta ttccaatgac agcaccaata atcccactaa 815160
aaacaattat cagtaaagtt cttaaagcat ccataaacat aacgacagtt ataaattctt 815220
ctttaacttc agtttcttca acaatttcaa ttttgtcata gacagctaac gaatcttccc 815280
atcttttctt taattgacta cgctttgaag atagtttaag catatctcta ttaatttttt 815340
ttatatttcc tggactaaat ggcaatttaa ttgcgctaag tcgcaagatt ccattttcaa 815400
ttatatcctg ctgataatgc aaccctaaaa aatgttccat tctccttgca agcgtttgaa 815460
aatcttcact accgccatca tcataatgac ccgttaactt ttcttttggt ctaacacaaa 815520
ctaaatgcca aatattactt gttttattgg gcgttttctc aaaaactcta atagctcgtc 815580
cacgcatttg attacttaac atatatgagc ctacaaagct agccaaaata agcgaattaa 815640
cacacggtga atcccaacct tctccaagta aagatttagt tcctatcaaa acttgcatat 815700
aaccctgcgc aaatacctca ctgattaccc ctgttataaa attacggttt ccactaattt 815760
caacttttac ataatcatct aattttccaa tttgatggaa gctgatttta ctaggttctt 815820
caactaattc tattaatgct gtttgagcat ccttggggat aataatcatt gtgccacata 815880
aaacaccaaa tttaattgct gtcttatttt tagcactatc acgccttagt tgttcaaaaa 815940
atggtaaaac gcctaaatta ttcacatctt tgctttcatc acctaatgcc cgttcgtatt 816000
cttttcgaat ataatcagta agaatcaaaa gtcgtaattc ttgtttcatc gttttatatt 816060
cataattaac aatttcttta atgctttcac atttaccaac cgaatttatt agcatttttt 816120
caattgcttg atttaaacac aaagaaactt ttcgtttttc gattaaacct ttagacttca 816180
attcacgaat caattcatca cggtattgtt cttcaactcg atatgaagca atatcatcat 816240
ataaaaagcc ttgcagtaaa atttctaacc atttaagtga taagggttct aacgatttat 816300
atcctaaaag cttttgatac ttattcgcac tgcacactcc cttagtattt aaaaaaatta 816360
tcattgctga taaatagctc ggatcatcta atagctcatc atcacttact tcctcagtaa 816420
aaaagcgatg actcataata gccttacaaa aatattcatc ttgtattagc tgctccaaaa 816480
tactttgact attttcctca aagatactta atttttgttt ttcttgagag gccggataat 816540
tgaaataaac ataatcttga tgtggacata aagtaccatc tttaactaat tctggaactg 816600
ttatctcttc atcaatatca ccacacatat ccatatacct agtccacatg cttagattag 816660
aatcatatgg cggagttgct gttagagcca ctgtgaaaat attattaaat gcttttttaa 816720
attcttctaa tgatttccac cactcacttc gaagatgatg acattcatct agacataaag 816780
ttcctaattg gcattcttta aaattactga ttacatcaaa attatgataa tcaacttctt 816840
caactgtttt aaattcatca ttagtctcta ctagttcacc acaataatga ctcatcgcac 816900
tatgtagtgc ctgatatgtc acgacagtaa ttaattttgg tttttttaaa tcttgagaaa 816960
gatattgatc gcgattttct tgtttaacta aaaaagcttc acaaatacgc tctacccatt 817020
gttcacgaat cgttattgat gggactaaga ttaaagccga gtaatcgatt ctttttatta 817080
attcaattcc caaagttgtt tttcctgaac caggtgcagc aacaatatga attttacgat 817140
cttgactata acggtcatat ttatcaagaa cacgttgttg ataactgcgc caagtgccct 817200
tgaaatgcaa aatttgttct aacatccaat ccctcctatt acctttattt atacatatca 817260
accttaaaac atcaatacaa atcaacttaa ttttatgata aaaattctcc ttccactaaa 817320
aaagtagtac aataataatc aaaggtggtg taattatgac gatgtatatt caaacccaaa 817380
atcaatatac ccaattccaa agtgatgagt taactgattt acttggtaag attagtttta 817440
ctatcaataa atttggactt tggcaaagta atcacgatac tagagcaaat tatattactg 817500
atgatattga aattgtctat tatcgagaag gtgggtctat tacaaccatt ggcaataaaa 817560
aatacacctg cccaccccac agctttctca tcatcgaacc ctataagctc aacacttcaa 817620
taaatactgg aaatactaac tacagctatt atttttttca ttttgatatt gaacccctat 817680
cattgcgcca acaatttatt actctcttaa caaaacacgg gcatttaata tataaagaag 817740
aaataaaaga cttcaaagaa atgctagaac gtttattaat cgaagctagt gaaaaagaaa 817800
ttggctattc aagcattata acctctgctt tgattcgagt tgttgtagag ataatccgcg 817860
ctcagcttaa aaggaataat gaccatattt cacaaataac agatttacca catatcgaat 817920
tagttaatga tgccattaag tatattcatg accatcttca tgaaccaatt aaactaaccg 817980
caatggcttt acaactaggt gtttcaacaa gtatgttata taaatctttt attgcaattt 818040
tagcaattcc tccactaact tatattcatc aacaaaaagt tctctatgct caaagaatgc 818100
tggctcatgg taaaagtgtt acaatgattg caaatgacct gggatattca tcagcctatc 818160
atctatctaa aacttttaaa caaatcacag gggtcagtcc acgtgaatat aagaaaaata 818220
ttaagttatt ataagcatat acgaaaatgt atatgttttt taattgatat aatatgtttt 818280
atatatatgt aagtgctatc atatctttat aagggaggta tgaatttgga aaataaatat 818340
caaaaactct ttcaaccaat aaaaattaat cagctggaag taaaaaatcg aatttttatg 818400
tcgccaatgt caacaaactt tgcaacaaaa gatgggtatg ttactgatga aatgatctat 818460
tactatagca gaagagcaaa aggtggcgtt ggtctgattg taactgaagt aacaatgatt 818520
gagccaacct acaaatatat tgctcatact ttatcagttc aagatgattc ctatcttgaa 818580
ggatggcaaa aattagctaa tgaaattcat aagtatgata gtaaggtcgt agcccaacta 818640
ctacacccag catatatggc aattcctttc ccggaaacac cacaattagt tggtccaagt 818700
gaggttggtc catactatgc taaaactcct ccgcgacctt tgacaaaaga agaaatcagt 818760
ataattgttg aacaatttgg tgatggtgcc ttacggttaa aaaaagcagg aatagatggt 818820
gttgaaattc atgctgcaca cgcacatgca ttactaggag gatttttatc tccactctat 818880
aataaacgaa ttgatgaata cggtggtgac ataactcatc gcattcgtct acttttagaa 818940
gtaattgcaa atgttcgaaa aaaatgtggg cgtgatttcg ctattattgt tcgtatcagc 819000
ggtgatgatt atgaagccgg cggacaatca ttacacgaag gatgttatat tgctaaaaga 819060
ttagaagctg ctcaagttga tatgatccat gtttctgggg gaactactat ccaccgcggc 819120
agctcaattg caccccctgg aacaccacaa gcgagtcata ttgacagcgc acgagaaata 819180
aaaaaatgtg ttaatatccc tgtttcaacc gtaggacgtt tgaatgaacc ttggattctc 819240
gaagaagttt tagaaagaga tttagcagac gtatgtatgg taggtcgctc actcttatgt 819300
gatcctgatt ttgttaataa gatcaaaaat ggtcaagaag atgatattcg tccatgtatt 819360
ggatgcttgg gatgtttaag ctcgaccatg ttaaaagatc atgttgaatg tggaattaat 819420
ccatcattga caagtgagaa tgaagaaact gtaacacctg cgacaatatc ccaaaatatc 819480
ctagttatcg gaggaggtcc agctggatta gaggcagctt atattttatc aaagcgtgga 819540
cacaaagtta cccttgctga acgtcatcat acattaggcg gcgcaatgat cgttgcaggt 819600
tatcctattg ctaaacagca ctttgctcaa actactaaat atttcattaa acgagtaatc 819660
gattgtaata tcaaaattga attaaacacg attgttgatc aagcctattt atcacagcat 819720
cattatgatc atatcatcgt cgcaaccgga gccaaaccat tacgacttga tatttttaaa 819780
aatcatcctc atactggtac cggacaagat gtgcttcttg gcaaaatgtg gacaggtaaa 819840
aatattgtcg ttgttggagg aggctctgtt ggctgtgaag ttgctgattt tgttgcccca 819900
ttagttaatg accgccatcc aaataataaa aaagtaactg ttattgaaat gaaatcaaat 819960
attattatgg atgatacttc accatcacga agtattttag ttcaaaggat ggctgataaa 820020
ggcgtgaaca ttattactga tagtagagtc gttaaagtta caccaacaac tctcgaatat 820080
caaaaagatg gcaatactat tacaattgag aatgttgata caatcattga agctactggt 820140
tattatgctg atcatgagtt aaaaaaaacc ctcgatcaaa tgcaacttag ctacaacgtc 820200
ttaggtgacg ctgcaacccc aggaaaaatt aaaaatgcta taagtgacgc atatcattta 820260
tgtaaaaata tttaatcaaa ggagaaaata tatgaattta ctaaaaccta ttaaagttgg 820320
aaaaattact ttaaaaaacc gaattatgtt tcccccaatg acaaccgggt atgaagaaag 820380
agatggttca atcggtgaac aaagttttaa tttctataaa cgtttagcgc aaggcgatgt 820440
tgcttatatt gttttaggtg atgttgctcc agtcaatact gtttccccta cacctaaact 820500
ttttcatgac ggtcaaatcg aagctttcaa aaaattaagc gatgccttac atgagtatga 820560
ttgcaaacta gggattcaaa tctttcatcc tgaatatgat gttgatgctc tagcagaatt 820620
atttagaaaa ggtgatatgc aggctgcacg tgctaaatta catcatgaca tgctacatta 820680
tatcgatgaa gtaactgaag cccagcttac agcaattatt gataaaatcg gcgcttgtgt 820740
taagcgtgct gccgccgcgg gggtggatgt tattgaggtt catggtgatc gtcttgtcgg 820800
ttccctttgc tcaaccattc taaatcaccg aaatgataat tatggtggtt catttgaaaa 820860
ccgtattcgc tttgctctcg aagttgtcaa agtaattaaa gaaaatgctc cagatatttg 820920
catcgattat aaactgccaa ttatcactga aaatccgctt cgtggtaaag gaggcctaaa 820980
aattgatgaa gctattaaat tggctactat cttagaggct catggagttg atatgatcca 821040
tgttggtcaa gccaatcata ctggaaatat gaatgatacc attcctgcaa tgggaactca 821100
accatactgt tttatgaata aatatacaaa acaaattaaa gatgttgtta cgattccagt 821160
gtcttctgtt ggacgaatcc ttactcccca aaatggtgaa tccttgattg ataacgggat 821220
ttgtgacatt attggtttag gtcgttcatt attagctgat cctgattatg ttaaaaaatt 821280
aaaaaataat gaagctgctc gaattcgtca ttgtatgatg tgtaataaag gctgtaccga 821340
tgcaatccaa aatagacaat ttttaagctg tgttttaaat gctgaaaatg gttatgaata 821400
caaacgaata attaccccag cagcaacaaa gaaaaaaatt gtagttgttg gagggggacc 821460
agcaggttta gaagctgctc gggtagcaaa aacaaaagga catgatgtta ttttatttga 821520
acaagacact agattaggtg gtcaacttaa tattgcagcg attccaccac gtaaagctga 821580
aatgaatcgg gctatcaatt acttatcaaa tgaaatgaaa atattgaatg ttgatttaag 821640
attaggtaaa aaagcaacta gtacagatat attaaacgaa catcctgata gtgttatcat 821700
cgctgttggt gccaataatg cttccctacc aattcctggc agtgatttaa ctcatgtgtt 821760
agatgcttgg aaagttctta actatgaaca attccctagt ggccatgtag cgattattgg 821820
cggtggtcta gtcggagcgg aaactgcaga atttttagca caaatgggct tggacgttac 821880
tgtcatagaa atgcttgaag aaattgcaaa agaagaatca tcaactgtaa agccagtaat 821940
gtttgaagat tttgaaaaac atcaagttaa attattgact aaaacaaagg taattgaaat 822000
taaaaacgat tgtatcaaag ctgctaatgg cgatggtgaa ttaacgattc catgtgatta 822060
tgttatttta gctactggag ctaaacctaa tccatttgat gtcagtgaat taacagctca 822120
caatattgat attcatcttg ttggtgactg caatgaaaaa gctgctgata ttaataatgc 822180
cattactcaa ggttatttag cagccaacag tatttaaaac tcttattatc tagactaaaa 822240
agaattaatc ataacattta aatgtttaag attaattctt ttttattctt attaactatc 822300
tactattact agccattcta aaccacgtat aattttttcc tttgattgat actgataatt 822360
gataaatatt ttctggccaa gtacatccgc caaagcctcc atccccgata gcatgaatat 822420
cacatccggt ttgtttcatt aaaagggcaa cctgccgaat tgtatcctca tcggcacatt 822480
cgaccgaact atttaaaaaa ctcatggcta aagtacctgg tttatagcga tgaatatatt 822540
ctactaattc tctaatcata tctactgtga ttcctgctct agtccctgga gctggtaaat 822600
cgatacagtc agcaccagca tcaataagtc ttttaataac atctttggta tcatatgctg 822660
ctaaaggatc acctagtacc ttttcttcga taccatcttc ccacttgcca gcaaacaaga 822720
aaatatcatc tccacatatt tcttttacta atttggttgc ttcaattaca tcttcaatcg 822780
atgttccaga acctggatta ccacccaata caataaaatc cactcctaaa gcaactgctt 822840
ttaaaatatg ttcttttgtt gctaacattc cagccaatcg gtaaagtgtt ttttcatcag 822900
aacgcttttc tcccttctta ggacacccta aataaacacc aattggacaa ttgcattttt 822960
ctttaagctc tttgatagtt aagccgcaca atcctggatt attttcaaaa ttatctaaat 823020
ctatagtatt aagcataacc atatctgcac caaacgaaca aagcaattca gcatttgtca 823080
cacccattac cgtccctggg ccagcaaaaa ttaaatgttg tcccatgata actcgacctt 823140
ccgatttata gatagattct tttaattcta aaggacccat tttgtttatc tcactctttg 823200
aagcattaat caatcttttt acgttgctca taatttttcc tcatttctag attttgtttt 823260
cttcaagtgt tttttcttga ttactttttt tctctgcttc taaagcctga ttgtcacaaa 823320
tcttaaaaaa tgggtaataa attatacatg ataacaagca cataattaca atcatgattc 823380
ctaaactaat tcccccacct aaaataaatc ccgcaattgg acctggaatt gtcattacac 823440
ttaacattaa ggcgggaata ttcacaacac ctgtaaccat caacaaataa ccaataatca 823500
taaatacaag tggtgttaaa ataaacggaa taaacataat tggatttaat acgattggaa 823560
aaccaaaaat aacaggctct acgatattaa acatccccgg aacaaaacac acttttccaa 823620
acgctttaaa acgttcgctt ttagcaaata ttgccatatc gcaagtaagc ccaaataaac 823680
atcctggtcc accaataaac tgacaaaaaa caaagaaaaa catataagtt gtgactaagg 823740
ttacaggttc tccggccata taattattta aatttgtaat tgctggttcc atccaaatta 823800
ccatcatgac agaaagtaca actgaagtac catgaattcc aacccaccat aacagcaata 823860
atattaacat actaatcaac atggctggaa aactattacc taaacttact aaaggcgctt 823920
gaaccatagt ataaataaaa ttttgaatat ttccataaga tgttacagca aatccagacc 823980
ttaccaataa aaacaaggct gatactaaaa atgctggaac aacagcttca aatggtttag 824040
aaaccatttc cggtaccgaa tctggtaatt ttattttcca attatgatta acggcaaaag 824100
caaaaacata tgccccaata atcccacata acatggcagt gaagatacca ctagcaccta 824160
agttatcaac tgggataaca ttttttatca atgttacagc tccatttgta ttatcaacat 824220
tgttataaga aaatggtgta accaacaata gtgataataa cgaaacaatt gctgtttgaa 824280
atggattaac attaaacttt tcacctaaat tataacctaa agcaaaaatg aaatataatg 824340
ctgttaaatt acaaacagca acccctacag ctaaagcatc agatattcca gtagacgata 824400
aaaaatttgt ataccagtct cccaatggta aaccctgaaa taatgaaaat acagctcctc 824460
ctaataacgc tggcatcact ttcataaatg cgccacttat tgcacttaaa ataaaattgt 824520
tttcaatctt ctgtgcaaaa ggtataactt tattttggat aaaatcattc ataatttttc 824580
ctcctcctaa ctttataact acattttatc tagaagtata atcatttaag agtacataaa 824640
acttttcatt agtccaaaat aaaaaccaat aaaaaaaata agtgctaagg tttcattttt 824700
tgaaacttta atacttatcc ttggttattt aatcttgcta ataagctttc aataatcttc 824760
attaattcaa atttcttctt aatccttggc tgttcgtgta tctctaaaaa acgtttatga 824820
gtatacgagc tctttaaaga tatgatataa ttattttcgt catttaaatg tctataaata 824880
ttcctgatca aagcattgga tatattataa tcatagtatt tttctaaact tatctgaaga 824940
tgactataaa aatataacgt atgttcatcc atattaatag ctaaattgtt atcttcttca 825000
ttaattatat aaatatcata acctaataca taaaaatatt tcaaatacat tttccaaatc 825060
aacattgctt ctcgctcacc aaataaaata atttgatgac aatgattaca tgctataact 825120
aaatcatcaa gtttatcacg atcatcgagc aaataaataa aatcacaaat cacagcatta 825180
aattctctta caaaagtctt tttaaaatcc gtgaaatgac tagtttttat acttttacaa 825240
aatctaatga ttgatgattt agatagaccg gtatcataaa taacatcctc taaagatagt 825300
tctattagct tttccctttg gtttaaaaaa tatttaacaa gaatttgatc cgtattattg 825360
atttttgcat tcattgatat atctaaaagt atatcgatca ttttatcact gctcctgata 825420
aataatctcg tgataataaa atttaatcaa atcaaaataa tacaacaaca aatactcagt 825480
ctcaaacatt tcattattag ataatatatt aattacctca aaaacattgt aatgaaaatt 825540
tatttttgtt tcgcctgaaa aaataataac tttattagct ttatttccta aaatcgacac 825600
taaattatca tcagataaaa aaagtctacc agtacctgaa atcaatataa ttaaatcatt 825660
atcctctatt tcaatagaat tatcttttaa taaagacgac attatcactg tcttccccat 825720
tgaaatcata tcaatttgaa aattaaaaag aattggagtt atcgtagggg aagcaacaat 825780
aataactctc tgactttgag ctatttcttt aatgatcaac tttaatttca ttttatcatt 825840
gaattctaat ggataatcaa ctaaatgtga aaccgccgca gctaatcgtt ttttgttaaa 825900
aatcttataa cctcgatata tttgatcttt acgaacatcc aattcacttt ctaatctttc 825960
tttaaaaatc gaataattag aataaccaaa tttttttaaa aactgtttta ctgttggaac 826020
tgaaacaaaa cagccatcag ccacatcttg taaagtaata cttcctatat gattaatatt 826080
ttctataata tatttggcaa tataataatt taaatcttta ttattagagt tattaacaat 826140
tgataaaaaa taagctaagc acataaacat attatcttcc tccactcatt attaccatta 826200
tataatatta attaaattta ttcatttaaa aattagcttt cttgtaccag caaaaagctc 826260
caatcaaatt tgcatcatta taataatgac acactttgat ctctggtgga gttaccggaa 826320
ctgggatgca atcaaataaa tcactcactt ctttctttaa cattgttaat aataacggct 826380
gagtactaat ccctccacca atactaatat tctctaaatc taataacatt tgcatattaa 826440
aaatatatct tgcaagattt ttagtataat cccgtagtat ttctaaacta gcaatatcat 826500
tatgattagc cttgttaaaa aaggctaatc catcgatcga atttcgctct aatgcaaatc 826560
gtttttcata atttctcgtt aaataaccta caccgccaat caatccaaat gtattttgcc 826620
aatcaaagtc atgtttagaa tcaattaaag aaaacgtagc tgctccagca aaataattac 826680
acccacgata taattccccg ttaataataa ttgcgcatcc aactccagta cccaatacta 826740
gtactgcccc attactcgtt tcttttaatg agcctctata caattctgct aatgccgcac 826800
aattaccatc attttcaatc gaaactggta cgtggcattt actccaaagg atttgtttaa 826860
tatttttatt atcattaaat ctataactac caccattttt tattaaacct gtaaagggat 826920
tcatttcccc acaataacta atcgcaattc cggataattt catgtgtata gttttaaata 826980
aatccactac ccaggtaatc atttcatcat gactttgaaa tattttattt tctttattta 827040
catcatataa ctgaaagttt tcatcaataa ttgcatattt aactccggtg ccaccaaaat 827100
ctaaacataa atatttcatt atttaatccc tcatttctta acactttaaa gttatcatag 827160
ttaaaaaaaa tataaatact atataatttt tggttgtgtc aaaaaatgaa acatagaaat 827220
ctaatatgaa ctgttagcta tgattattgt attgcagcaa ataaatcttt atctttgtta 827280
atatcttctt gaatgacttt tttgatatat aaagctaaca tatatggcat tttttcttca 827340
aatgtatcta actggcaatt taataattcc ttgactttag tcattctata attaatcgta 827400
tttcggtgca tatataaatt tttggccatc gctacttgac tgccatcatg aatcaggtaa 827460
tagaacaatg tcttttctaa ttcactatga tgtttttgat cataatctat taaaggcttt 827520
aataaatgct gatacattcc tgataaaatt tgtttatcct cgattgaaaa taagatttga 827580
taaactccca tctcttcaaa aagaatcatc ggatatttaa attgttctgc cattgcaact 827640
gcagctcgag ctcgtttata acttaagatt acttgtctaa aatctgtcat tggcgttcca 827700
atacctaagt gaataaatct tgaaggcatt cgcttctttg ttcttttata cattttatca 827760
gtaattttct ctaatgaatc cggatctaaa ttatttacaa ttaatacaaa atatccatca 827820
aaccaaaaaa atgtatatgg gctttgtatt ttttcaaaac ataattccaa ttgaaaagaa 827880
actctacgtc gttcaattgc atcaaactga tcagaatctt caattccaat taaaacaact 827940
tgaaaaaaac catccacatc aaatgcacct aacaattgct gccgaacctc ctcaacaact 828000
tgaggagttg taaaaacatt ctgaaataat tttgaaatct gattgtcttc tcgttgtgaa 828060
tataaacagc gcatactaaa atccttaatt aaatctgcca tgtgtacttc ccagggtgtc 828120
gttaacagcg gaaaatcctg ctcattacaa tagtcaatta tatcttgagg aatttcaaat 828180
atatatttac ctgtattgat aactaatcca acactatggt atttaaccaa acacttgata 828240
aaatcaaata acgaatcgtg actttgaaat cctaaacctg ttgtaactgc caattctttt 828300
ccccataatt gttgaataat tgtcgtatcc tcaatcatgt gaacccaact catcgcattt 828360
gaacagccct cacgaccagc taacaatttt aaatgatatt gctcttgagt ttgtactaac 828420
gcatcttcaa tcgtaaatcc cattttactc acttccttta tatttatttt accattattt 828480
gtgcatgatg cacaaataaa tcttattttt ttattatttc tgtctctata attattaaaa 828540
tattaatata taatataatt gtattaaaaa tagaacatct aggagggaca taacatgaac 828600
atttcttatg gatattacgt actaactgac aactttgata cttgcccaac ttgggttcgt 828660
gatgaaggat atttcaattg tgaaaacttt tcaaaattct ttaagttttt taaaaagaaa 828720
taaataataa tgagcattca taacgaatgc tctttttctt ttaagattta aattatgcta 828780
ttagataatt attttatatt taaagcagct tcataacctt ctttaactgc tggtaaagca 828840
ttacctgcct taattgcgcc acctactact tgaacatctt cacataattc atttgcaatt 828900
ttttctaacg gattataggc tttatatcca aatgctaaga caactaagtc agcagaaata 828960
acttcttttt ctccctgttc attaataaat gccactccat catctaaaat ttctgtcaca 829020
gtacaattag ctctggcagt tactcctgat tcattcataa ttggtaatag acagctcata 829080
ttaatgggat ccatatcagt caaaacagct ggtttcattt ctagaactgt tacatgacga 829140
tgcgtttgag caataaatgt ggcagtttca caaccaactt cgccccctcc gcaaacaacg 829200
atatgctcaa cttttgtagc gatttttcct aataacacat cttcagcatt gactacattt 829260
tctttatcga tacctttgac tgccggcacc agcggtcttg ctccagtagc caaaataata 829320
gcatccgggt tttcttgttc aatcatctct tttgttacta aagtatttaa atgtactttt 829380
acatgcagat cctctaaatt ctttttaaat acagatatta atgttgttaa ttctccttta 829440
ccaattggat aagctgcaga tctaaattga ccgccaactt cttcctgagc ctcataaaca 829500
gttacattgt gacctatcat tgccgcagtt tcagccgcct gcagaccagc aggtccccct 829560
ccaacaatca ttactttttt tgctttttct acaatgttca ttgaattttc atattcacgt 829620
cctacccgtg gattaactaa gcaagtgact tcttgattaa aaaataatgg catttcacat 829680
ccttgtagac acccgataca cattttaata ttcccatatt tttctgcctt tgctttatta 829740
ggtaaatctg gatcagtcaa tgaaccacgc cccattccaa taaaatcagc tttatccatg 829800
ttaattaatg tatctgccat ttgcggatcg ttaattcgat tagttacaat tactggtaaa 829860
tcaaccaatt tctttacttg tgctgatatc tccatattca atgcatgttc cgtaaacatt 829920
ggagcaatta ctgctctatt tccaggtgaa gcataagagc cattagaaat atgaatacca 829980
tcaaaaccta attcttcaaa aatcatacat aattcataag tttctgcttc agttcttcca 830040
ccatgaacat attcattacc agaaagacgg acgataattg gaaaatcatc accaacttgt 830100
tttctcattt ctaaataaat ttcagcaact attcgtactc tattctgtag acaaccacca 830160
tagttatcaa ctcgcttatt gacaaatggt gataaaaact ccgctaataa ataaccatgg 830220
gcacagtgta gctcaattcc atcaaaacca gcttctttag cgcgtttagc agcactacca 830280
aaatctttta ctaattgatt gatttcagca actgtgatat ctcttggttg ttcttgacat 830340
aagggacatt caattgctga aggagcaact ggcatatgat cttcattagc aattctagta 830400
gtttgtctac ctggatgata catttgacaa aagatttttg attcatactt atgaaccatc 830460
gttgttaatt gtttatttcc ttcaatcaat tcatctttat ataaaccggg aattctttga 830520
tatcctttac catattgttg aactgcataa tcctcagtaa taatcaaacc ccagccgcct 830580
ttagcctttt cttcaatata tttcatataa cgctcagtaa ttttaccttc aatcgtacaa 830640
taatttgtca ccattgccgg aactactaaa cgattaggaa tttttacagt tcctatttga 830700
taaggggtaa ataatttttt taaagccatt ttaatatcct ccaatccttt tataacttta 830760
ttttacagta tcaaatgatt tgaaggtcaa ctctaattta ttatatgtga tattattcac 830820
atattctttt ttaatcacat atattttact aaaacaacat aaaaaactct caagctattt 830880
gagagttttt tataatcgga atttgtattt ctaaataccg tttaaaacga tcaccttcat 830940
atccacgccc cctaataatc ccccgtattg gtaactgtac atgataacct ttatcttgag 831000
catacattac tgctgcttca taacactcat gactaaactg tcctaacggt cccatttcta 831060
ttaccgtgca taaacaataa tgagccggaa taattgtata cttcttttta taagaaatac 831120
ttaatccatt aaaatattcc tcatcaatag caaaatacca ttcatcttta tctttattaa 831180
aacaaacata actatcaata aaattaatat atttatcatt taataaaaat cgaatattat 831240
cttcactagt attaacttta tcataatcat caccaattcc atctacaaaa tcaaaagcat 831300
attttttatt aattttcttt acccaataat ttgataaatt taaatcagct acctccagtt 831360
gcattgccaa ctctgtgact cgttttttca acatgacttt ataatcaatc tctttattta 831420
gtcgcctttg gaaaatatgt aactgatttt gaagcttttc tctataatta aaattaataa 831480
aattaggaat ttcttttatt ttcattccta aattctgata ctgtaaacat tctaataaaa 831540
tatatatgtc aaaaatacta taatagcgat acccattctt ttcatctctt ataggatcaa 831600
taattcccat tttttcataa tacctaatca tttcacttga taaattaaac aatcgtgaaa 831660
tatcccctat tttatactgg ctattcataa tatcagctcc tttacaaata attttatcac 831720
ttaatcttcc tatttaaaaa ataattttat tattagtttt tataaatcaa ctattggtag 831780
atttataaat taattaaaac tcgttataat caaaatataa aggagaaatc aatagatgga 831840
ttgtattaaa attggaaaat ttattgcgac atgctgtaaa gaaaaaactt aacccagatt 831900
gaaaaactaa atgtaacaaa taaagctata tcaaaatggt cgaaatttta tcgatgcttc 831960
attttatcac gattttcgcg atatcttagg cattactatt aacgaattat tagctggtga 832020
acatctcaat actcaagata atcaatatta ctatgaaatg aatcttcaca atcgtattaa 832080
cagttacaat aacataaatc gaaaaaataa aataattatt ttcatgattt ttagtacatt 832140
gattttttag tcattacgta tttacaaata aaaactatat ggatttttat catggattca 832200
atacatctaa aaatcattat ttagaaaagc aaattcttga tctatttcat tctttatcag 832260
tccctggcaa cacacatcca aactttgatg aactttatta tcggaaaata tttgaacagt 832320
ctgatagtag taaaatgtac tatatttata ccataaatac taagcaatat tattttattg 832380
aaaatatatt ctaaacaaaa taaaaggtat cacgaattat atgggagagg gtccgtgata 832440
ccttatatga ctattatagc atatttaaaa aaataagcat ttaatctgat taaactttaa 832500
ttagtttctc caaaagaaat ctagatttca agtattttag tctaaatata ttatactttt 832560
aatctctatt acaaagattt agaaatcttt atcaaatcaa ctaaaacaaa tctattctac 832620
atttcagtta gagcattgtt ttttataata aatcattttt acaagtcata tacctaacta 832680
accactatac caataattac tttaataata tttcaagaaa ttgatactta aaatattaat 832740
attcaatttc ttcaagtgca tttttcaatt gattcaaagc ttgtcttaaa tatgctcttg 832800
ggcaagcaat gttaattctt tgaaaccctt ttccttcttt tccaaacatc gttccactat 832860
ctagccataa tcgagcatgt tcaatcaata aatcatttaa ttctttatct gaaatttgta 832920
atcttctaaa atcaagccaa agcaaataag ttccctccgg gataatcaac tttatcaatg 832980
gtatgtgttc tttcaaatat tcatctacaa accgtgtatt ttcaaataaa tattgcttta 833040
aatcttcaag ccagcttgaa cacgattcat aagctgtctg gcaagctgct aatccaaaca 833100
aattacactg gctataacca gtactggcaa tagctttttt aaattgtaat ctcaattttt 833160
catcggcaat aaaaatattt gaaatttgta atccggccaa attaaaagtt ttagtaggag 833220
ccgtacaggt tattgtaata ttctgtaatt ctgtctttaa tgatgcaaaa acatgatgct 833280
gatgccccgg ataaataaaa tcactatgga tttcatcact aataatttta acatcatttt 833340
taaggcagat ttgccctaat tttaatagct catctttttt ccaaactcga ccaactggat 833400
tatgtggcga acataaaata aacaatttta ctttttcttt cttaatcttc tcttcaaaat 833460
catcaaagtc tatttcataa tgagcgtttt ttaaaactaa agaatttgtt ataacacgtc 833520
ttccgttatc aataattact tctttaaaag gataatatac tggtgtttga ataattactc 833580
catcacccaa tttagtaaat gcccgcactg cttgtgctaa agcaaataca acaccaggcg 833640
tcttaactat ccattccttt tttatttcgt aattaaattt tgaccgatac caactataaa 833700
tagcttgata ataaccatcc ttactatcac tatatccata aataccatga tttaccacat 833760
catataatcg ttgttgtatt tctggagcaa cgataaaatc catatctgcc acccataacg 833820
gtaaaatatc atcaggacgt tctctttcac tagtgaaatc atactttaag gagtttgtat 833880
tagtacggtt tattattgaa tcaaaattag atttcatcat tatcaccaaa agcctgcctc 833940
aaatcagcta ataaatcatc aatattttct attcctactg ataatcgcaa aaaattatct 834000
gtaattccta atttagctct aatttctgct ggaacatcac catgggtttg aatcattgga 834060
taagtaatca atgactccac acctccaaga ctttctgcat aagtaattaa ttgtacattt 834120
tctaaaatct tttttgctaa aaaatgattt tcaacactaa aggctatcat gctgccaaag 834180
ccgcgggctt gatttctatt gatttcatat cctggatgct ctattaaacc aggataataa 834240
actttgctaa cccgcggatg ccgatttaac cagtttgaaa ttttcagcgc attttcttgt 834300
tgcgattttt gtctgattgc cagcgtcttg atcccccgaa tcaataaata acaatctagt 834360
ggtgacaagc tatttccaac tgtctttgaa acttctctaa tccttttagc tagtttatga 834420
tcaccagtcg aaatacttcc agcaataata tcattatgcc cacttagaaa cttagtagca 834480
ctatgaatta caatatcagc acctaataat aatggatttt gaaaatatgg tgaaaggaag 834540
gtattatcaa caattagtaa cagcttgtgg gcttgacaca aggcactaat tttttttaaa 834600
tcacttattt gcattgttgg gttactcggc gtttcaataa aaacagcttt tgtttgagga 834660
cgaatatact gcttaaaact ctttaaatta gttgtatcaa cataactgaa ttttaaacct 834720
ttattttgct gcaaagtaaa tagtcgagtt gaaccgccat ataaatcatt tgaacatatc 834780
aaatgatcac cactactaaa aagttctagt accaatgaaa ttgctgccat tccactagaa 834840
caagcaactg tatcaactgc gccctctaaa ttggaaataa tctcttctaa ataagctctt 834900
gttggattac tttcacgaga gtagttatgc cctctgcttt ccccaatccc aggatgagaa 834960
aaaattgctg tttggtatat tggaattgaa acagcaccat aaggatgctg tttcaattct 835020
aaatttgcag gatgaataca acgagtttca aattcatatt tcatactttt ctccatttcc 835080
ccacgctaag cgcatggaca caaatatttc ttgaaagaca ttctgattcc ttctactcta 835140
ctaccccctg ctataatgaa agggaggtag tatactacag agcacgagaa gtagagtagg 835200
taattctact cgttagaata tcttgtataa ttataagtcg ccgtcatctt ttcgagcaca 835260
aataattagg actcagagcc tggacactta ttattgatat attaccaatt tggtcatatt 835320
gctagatgac agtcagtacc acttcttctt tctttgaaag gaggttttat tttttgtagc 835380
ggccatcgct gcttctggtg ataataatgt cacgacctat attcaaaagc agttttctac 835440
ttttaactct gatttgttga atcttttaaa ctggcttaaa tcaaacaact gttttgatgt 835500
ttgcatggaa tctaccagta agtactggat tcctgtcttt aatatccttg aatctgaact 835560
caatattttt cttactcatc ctaaatacgt gaaggtgatt agaagtaaga aaaccgataa 835620
gaaagattca aaatggattg ctaacatctt taaacaagat cttctcaagt actcttttat 835680
tccacctaaa aacattagag aacttagaaa aatatcacat tatcgcatta aacttgtcaa 835740
taagcgctct tctgaacgca atcgttatca aaactgtatg actgtttcta atattgcctt 835800
agcttctgtc tctactgatc atttaggaaa gaattgtaaa gctgccatgg atgagattct 835860
caaaagtgat attatcactg aagacaatct taagaaaatt ctcaagggtt ctgtttcaaa 835920
gaaatctgat caaatttttc aagccattca gaattctcac attgaatctg accaaagatt 835980
caaaatcaac tgcactataa aacacatgaa taatcttgac gaatatattc aaaactggtt 836040
agtatttgaa accacttctt gttcaatgtg ctctttcggc tatcaagagt gaaaaagaaa 836100
catatttcag aatcaagtat aatcgtatta agaaacgacg tggtcataag aaagctatta 836160
tagcgaccgc tagaatgatt cttatttcta tataccatat gacaaaaact ggtgaaaact 836220
tcaatccatc tgattatgaa tcattaaaaa atccaaaacc aggcaaccag aagataacca 836280
ctcatcaagc attagaatta ttgaaatcca tggatattga tataagccaa atcaatttat 836340
cttctattca acaaacgagt tcatcatgaa tttttaattt tttaggtcgg ctttttttat 836400
aaatttcttt cacacttatc cccttttaat tatagctagg tacataccat aaaccattat 836460
tatttttatc taaatattct ttaaattctt ttgaacgata agcttcaaca attgctttag 836520
cccattttgt atctttattt ttttctttta caactacttg taacaataaa tgttctaaaa 836580
catcctcctg taataacgca ctcgaagcat caattcctgc attataaact atgctgccgg 836640
tgattacagc ataatcaaac tcatctaaag cttgaggaat cattgttgaa tccatttctg 836700
taaactctat ttcataagga tttttaataa tatcatcttt tgtcacggaa ctaatatcca 836760
catctggatc taaagtaata tactttgctt tttgtaataa aacatatgct ctagatgtat 836820
ttgaagcatc gtttggtaca gcaatcttag cgcccttttt aatttcctct aagcttttat 836880
gagtatttga gaaaattcct gcaggtacag ttggaattgc tgtcaaagct actaaatcac 836940
catcttgtga ttcattaaaa tttttcatgt aagctgtatg ctgctcaaca ttgacatcta 837000
tctcgccttc atttaaggct gtatcatttt gcaataaatc tgaaaattcg atgcatttaa 837060
attgataacc ttcttttttc aaaattggaa taatggcatc ttcaaataag actgtatatg 837120
gccccgctgc cttaccatag ataattgttg tcttatcttc acttttatca ctactacttt 837180
ggcatccggc caaaacaaaa accatcacta ataataaact caatattctc tttttcattt 837240
ttcttcccct attcatgtgt tctaattttt ttagataaat gatttcccaa tgtttgaatt 837300
aattgtacaa agataattaa aatgattacg gtaacaaaca ttagagtatt attaaaacgc 837360
tgataaccat aagttaatgc taaatcacca acaccaccgc cgccgattgt tccagccata 837420
gcagttgccc ccaataaacc gatcgttcca gtagtaagtg ctaaaactaa cgaagctttc 837480
gcctctggta ataaaaaata acgaatgatt tccaaagtat ttgcccccat tgctttagca 837540
gcttctaaaa ttcccggttg aacttctaat atagaacttt ctatcaaacg agccaaatat 837600
ggtgcaatat aaaatactaa tggaacaatt gcagcctttg ttcctattct tgttccaacc 837660
agcacttttg ttagcggagc aataaatact aataagatta caaatggcac agatctaaca 837720
atatttacta acccactcac aagaaaatga attgtatgat tggctttaac tccatttttt 837780
ctagtaagga ctaaaagtaa gcctagcggt attcctatca aggttccaaa aaataatgat 837840
attcccaaca tataaattgt ctggcctgcc gcttcaagta atttatcagc aggtatattt 837900
aaataatttt caatcataat tcaattccac cctctctatc ttcacatctt gtttttgaat 837960
ataatttatc gctcgaataa cttcatcctg ttcacctttt aactgaattg ttaaaattcc 838020
taaaatatct tctcctactt cattaactga agcaaataaa attgttgtta taattttaaa 838080
atgcttatta attttagaaa ttacatcatg ctttgtactt tcaccaaaaa aagtaagttt 838140
taaaaccgga taccgataat ctaattcttt taaaagtgtg gttggaatta cattgctaat 838200
aactgtttca acaaatctct ttgtcatttc ttgttgtgga ttactaaaaa cctctaaagt 838260
atcacctttc tcaatgattt taccagattt cattaccgct actttattac aaattttctt 838320
gattacattc atctcatgag ttattaacaa aattgttatc ccaagttcac aattaatttt 838380
tttaagcagc aataaaattg cttctgttgt ctgtggatct aaagcactag ttgcctcatc 838440
acagagtaaa atcttaggtt ctgtagctaa tgctctagca ataccaattc tttgtttttg 838500
acccccagac agttgtgata cataagtatc acgcttatct tccaattcca caaaagataa 838560
taattgttta actcttactt caatagcttt tttatccagt tttgaaagaa tcaatgggat 838620
agcaatgttt tgatagactg tttgtgattc taataaatta aactgttgaa aaatcatacc 838680
tatatctttt cgtaaaatat ttaattctcg ttcttttaaa tctataatat tttgattatt 838740
aatatagatt gccccatttt caggacgttc caataaattt accattcgta ataacgttga 838800
tttaccagcc ccagaataac cgattacacc gtaaatatca cccgcttcta cttctagaga 838860
gacatcttgc aatgctggaa cttcaccact tttagttgta aaagtcttat ttacgtgttc 838920
aattttaatc attctcatct gcctccaatt ttaaaagagc ctgtttcgcc aattggctaa 838980
gatattttgc agctaacgat aaagctgcag gatttacctt aaacttcgga tgatgattag 839040
gataggtctt tccggttccg attttaataa atgttcccct gattttttca agataaaatg 839100
caaaatcttc gcctcctaaa gttgcttcgg gtatccctat agcaattttt tctgcttgag 839160
caattgcttt agcaaaatta ctccattcct catcattgac ggttgcagga ggccccgcta 839220
tccactcaat ttctgtatca agatcatagg cttggctaat cccataagtt atttccttta 839280
atcgttttcc aaacagctcc ctctcctcgc tagtcagcgt tctaacagtc ccttcaatta 839340
aggcttgttc aggaataaca ttccacgtat tccctgcttg aagatgtgta atacttaaaa 839400
cactactatt aaaaggatcc atatttcgac taacgatcgt ttgtaagctg ttaactaatg 839460
cagcagctgc aacgattgga tctttagcca tttgtggatg ggctgcatgg cttccaaagc 839520
ccttcaaatt aattttaaat cgatcaacag cagctgaaac tgtccccgct ttaattccaa 839580
ttgttcccac ttcaaactgc gaagtactat gaattccaaa aattgcatta acatcatcta 839640
aaacccctgt ctcaataatt tttagagctc ctaatgaaga ctcttcagcc ggttgaaata 839700
ataattttac tgttccatgt aattgagcag cattttcatt taacaataaa gcaacaccat 839760
aaatcgttgt taaatgaaaa tcatgaccac aagcatgcat ctttccttca atctctgact 839820
tatagcttaa tgtcgtttcc tcattaactg gtaaagcatc aatatcactt cgtaaagcaa 839880
ttactttacc agggtatcca cctctaataa ctgcaactaa tccagttttt aatggtaaat 839940
ctaaaacttc aatatcatgc tcttgtaata atgttttaat tcttttagta gtttcatatt 840000
cctcataaga taattccgga ttacgatgaa accactcaaa ttgatattct aattcttttt 840060
gtaaactgtc gtcttccatt ctaattcccc ctttttaata acaaaagtgg gatgtttatg 840120
taaacatccc actaccccat ttaatatagt attaagaata tttgcataca cgaaaatgta 840180
ccctatactt ttgtatacag ctgcacatac acatatacat catatctctt ctgcttttta 840240
acatcatcgt tcgctcctct tcttttccta ctatatcgat aggtttgcta tgtaaagtat 840300
cttaacacac tataaatact ccgtcaagca aaaaaataaa tgtcaatatg tttgcataaa 840360
aaaaatagct aattagctat tcttcgttga tataaataaa ctcctaaagc agcaccaata 840420
ataatgatat atccaactat gctccatata tcaggaattt gatttaagaa aataaatcct 840480
aatatcgctg caaataatat ttgactataa tcatagattg aaatatcctt gccagctgca 840540
ttattatacg ccgcagtaat tgcaaattga ccaccagctg ccattaaccc tgcacctagt 840600
aagattaaaa actgttctaa actcatcggc tgataattaa ttattaaata tggtaacaca 840660
ctgagacaag aaaagcatga aaagaaaaat acaatttttg caccatttac cccctgctta 840720
cctagcttcc gcacacaagt ataagctatt cctgctccta atgcccccaa aacaccaata 840780
attgaatcca cattatttaa aagattaaaa gatggtttga ttacaaacaa gcttccaatg 840840
aaagctacga taattgatat tttttgtatt cttgtcgctt tttcttttaa aaacaaagag 840900
gaacaaataa ttacaaaaaa tggtgataat ttattaagca tcgaagcatc actaactaaa 840960
agatgatcaa ctgcataaaa attacaaaga attcccaacg ttccaaagac tgagcgtaat 841020
aaaagcatcg gtaaatcttt ttgtttatat gtaaatccct gtttactttt taataggata 841080
aaaaaagcaa ataaagcagc taccaaattt ctaaaaaaac ttttttgaat tgatggtaaa 841140
tcgccagcta attttacaaa tacattcatt gctgcaaaaa agaaagcggc taaaattata 841200
cacatcatcc ctttacggat attattcata agcacctcca gatactataa tgattatatc 841260
tattataacc attacgtcaa ttaatatgat ttacaacaaa aaggataact ttcgttatcc 841320
aattaattat tattgaacag caaatataag ttcagcttta caaactacct taccatttac 841380
cttagcaaca gcatcaccaa ttccaattgg tcctttttgt ttagttagag tacattccat 841440
ttctaaaaca tcaccaggcg ttacttgacc tttaaactta cacttattaa tgcccccaaa 841500
gaaagcaatt ttacctttat tttcttcttt agaaagaatt gcaatacacc caacttgagc 841560
taatgcctca acaatcaata ctcctggcat aacatgatgc tcaggaaaat gaccacaaaa 841620
atgcatttca ttaacactga cacatttaat tccttttgcc cactgtccag gctggtaatc 841680
agtaattcga tctactaaag caaaaggata acggtgcgga ttgatttctt gaatttgatt 841740
actatttagt tccattttct tattctccat atttcttaaa gatgatagtc gcattatgac 841800
caccaaatcc taatgaattt gacatagcta cattaacatc ttgatttcta ccagtatttg 841860
gaacgatatc taaatcacat aatggatctg gtttttgata attaatcgta gctggaataa 841920
atccctcttc gattgcttta acacaaatta ccccctcgat tcccccggca gcacctaaac 841980
aatgccccgt atttcctttc gtcgaagaaa tagcaacctt tttagcagct tcacctaaag 842040
cagatttaat tgccattgtt tcacctttat catttaaagg ggtactagtt ccatgtgcat 842100
taatataagt tacgtcttca gctactaaac cagcatcctt gattgcattg atcatcgctt 842160
tagccccacc agagccatct tctaaaggtg cagtaatatg atgagcatca caactgacac 842220
catatccgac catttcacaa tagatatgag cgccacgagc tttagcatgt tctaattctt 842280
caagtacaac aattccagca ccctcaccca taacaaatcc acaacgttcc tcgtcaaaag 842340
gaattgacgc ccgtttcgga tcattattat cacaaagagc tttcattgat gaaaagcctc 842400
caataccaag tggagtaata ctagcttctg ccccaccagc aaccataatt tcttgataac 842460
catcacggat atttctaaac gcatcaccaa tcgcattagt tccaccagcg caagctgtga 842520
ccggacaagt acataatcct tttgccccta attcaattgc aatatttccc gctgccaaat 842580
ttgtaattga cattggcaca aagaatggcg aaacacgatc ataacctttt tctaacccct 842640
tagtatgatc tttctcaatt gttgcaagcc ctccaattcc gcttgacaca actacaccaa 842700
aacggtcagc atcaatctct tcaatcttta aaccagcatc cttaaaagcc tctttagcag 842760
caattacacc aaattgagta aagcgatcca tttttcgaac tgctttttta tctaaataat 842820
cagcagcatt aaaatttttt acttcacctg caatttttac ttttgttaat tctttatcat 842880
agtttgtgat ttcgtcaatt ccacaaacac cttctttaat acttttccaa gtttcttcaa 842940
cattatgacc aattgcatta attgctccaa gccctgttac tacaactctt cttctttcca 843000
ttgtctctct ccttacattg ccattccgcc atcaacatgg atagtttgac cagtaatgta 843060
tctagcatca tcacttgcta aaaatactac cgtattagcg atatctctta cttgtccaaa 843120
agttcctaaa ggaatttgtt tagccatact ttctttaata tcttcaggta aaacatcagt 843180
cattgcagtt tgaataaaac ctggtgctac cgcattcaca gtaattcccc gactaccaac 843240
ttcgcgcgct aatgacattg tcattccaat aattccagct ttacttgctg aataatttac 843300
ttgaccagca tttcccatta ccccaactac tgatgacatt gaaataatac gaccataacg 843360
ttgtttcatc ataattttag tcgcatgttt catacaattc catgttcctt ttaaattaac 843420
atcaataact gcatcaaaat cattctcttt cattcgcatc aacaatccat ctttagtaat 843480
tccagcatta tttacaagaa catcgattcg accaaattct ttaatgattt ctttaaacat 843540
tgtttctgtt tcttcaaacg aagcaacatt agcttgagct aacataacag tcgcaccgat 843600
tgcttctaat tctgatttag ttgcttcagc aattttttta ttatcaccaa aattaacata 843660
atttacaatg atcttagcac cttcacgagc acaagttaaa caaatttctt taccaattcc 843720
ttgggctcca ccagttacta aaactacttt atcttttaat ttcatcttat tctcctttta 843780
atcccgctaa tgttttttct aatgatgctt gatcttcaac ttgataagtt ttaattgtct 843840
tatcaatctt acgaataaat ccacttaaaa ctttaccagg accgatttca ataattgtat 843900
caaccccgtt ttctaacata taacgaatac tatcttcaaa atatactgaa gacattactt 843960
gcttctctaa catttgagca atactaactc cagactcaag ttctttagcc gaactattga 844020
atattacagg aacttgcatt tcattaaaat taacacttac aaacttttct ttaagttcat 844080
tactagctgg tgctaataat tctgtatgga aaggtccact tgtatttaaa ggaattgccc 844140
gacgagcacc tttttctaat gctaattcgc tagccttagt aactgcctca gcctcaccac 844200
caattactaa ttgtcctgga caattatagt tagcaattga aacaactccc aaagccctag 844260
cttctttaac tgcttcattt aataattcgc gatctaagcc aataattgca atcattttgc 844320
tttcaattcc tgctgccgct ctttccatcg cttgaccacg gaaacgtact aaattaattg 844380
ctgtttgatc atctaaaaca cctgctgcat ttaaagctga atattcacca agacttaatc 844440
ctgctacata atctggagca attccatttt cttttaatag cttagttgct actacagcaa 844500
cagcaaccat acatggttgt gtatttcttg ttaaagaaag ttcttcaagg ggaccttcaa 844560
agcataattt ctttacatca atatctaagt caatgttatc aaaaacatct ttagcaattt 844620
gatagttatc atagaatgat tgacccattc caactacctg actaccttga ccagcatata 844680
caaatccaat cttacccatt attttagtcc tctctttaat tcatccatta attcttttac 844740
tgaaataatt ttatcattac gatatccatt gcttccacta aatactaatc cctcatccaa 844800
attaccttta gcagcattga tcaatgcacc actaatacaa taaggcgtag ttttaacatc 844860
acaaggaatt aagcaattat aacagcgttt tactggaatc ctttcatctt gtttaagtct 844920
ttttgtcaac ttcgtcatga tggctcttcc cggcattcca actggtgatt taacaatctc 844980
gatatctcct tttttagcat ttataaatgc ttgtttatat ttaatatctg catcacattc 845040
ctcagtacaa ataaaccgtg ttgccatttg aacaccatca gcacctaaat ctaaatactt 845100
ttgaatatcc tcactatcat aaacaccacc agctacaaaa ataggaatat ccttttgata 845160
tttttcaaca aatggttgaa cagtctcttt tacttcttta aaaatatcta ctaatttagc 845220
cgttgtttta tttaacacat cttctttatg aaagcctaga tgaccaccag cttcacttcc 845280
ttcaatgaca acaaagtctg gagctacctt aaatttacga tcccaagttt tacaaatcaa 845340
tttagcggct ttaccacttg atacaattgg ggcaatttta acttttgttc cttgaacaaa 845400
acttggtaag ttcataggta atccagcacc cgaaataatt gcatctattt tactttttac 845460
agctacttca actaaagctg catagtcagt aattgcgacc attgcattaa ttgcaaccat 845520
ccctttacct ttagcaatct ctttagcttt ctttatttca ttagctagct cacgtttatt 845580
agcttctagc ggattttttt caaaatcatc agcacgataa ccaggatgag cagttgaaat 845640
aacacccata ccaccattta aagcaacatt tccagccaaa tttccaagtg aaataccaac 845700
tcccatgcca ccttgtatga ttggtacatc aagagtcata tctccgatat ttaccttttt 845760
cataattaaa actcgctttc taatttctta aatgccttat cacaatcatc aaataattct 845820
ttaataatta cttttagagg tctaatttca ttgatcattc cgactacttg gccagccatt 845880
aatgaaccgg tatcggcgtc accttctaaa actgctctac gtagtgaacc taatgtatat 845940
ttttcaagtt ccatcatgtc agcaccttct ttttcacgct taacatactc tttagccatt 846000
ttatttttta ttacccgtac tggtgttcct gcgattcttc cagttactgt agtgcttgta 846060
tctttagctt tgattacagc ttgtttataa ttttcatgaa tcggacactc ttcgcttgca 846120
agcagacaag ttcctacctg tactccacaa gcccctagag catacgctgc caatacctgt 846180
tttccactcg caattccacc agctgctata acaggaacac taactgcttc aactacttga 846240
ggtactaatg ccattgtagt taattcacct atatgaccac ctgcctcagt tccttcaaca 846300
ataattgcat caacgttata tttttcaagg cgctttgcta aagctacact tggaacaact 846360
ggcaatactt taattcctgc tgctttccat gcagcaacat atttaccagg atttcctgct 846420
ccagttgtta cgaccggcac tttttcatca attactaatt gtgccatctc atcagcacaa 846480
ggattaatca acatgatatt gacaccaaaa ggtttatcag ttaaattacg gcaaatttca 846540
atattctttt ttaatgtagc agtgtccatt ccaccggcac caattaaacc aagtgcgcca 846600
gcattagata cactagctgc aaattcaccg gtagcgatat ttgccattcc tccttgaatc 846660
aaaggatatt caatatttaa taatttattt aatttcatct tctaactcca ttccattaat 846720
gttgcgcccc aagtaagacc accaccaaaa ccaacacaaa taattttgtc acctggtctt 846780
aacattcctt tttcattcat ttcacctaaa gccaaaggaa tgctagctgc tgatgtattc 846840
ccatattctt gcaaattcat ataaaactta tcttctgaag acttcatctt cttatataca 846900
tttttaataa tccgataatt tgcttgatga cagacaacgt aatcaatctc atcaagagtt 846960
aaatttgttt tttctaagat tgcattaata ctttcaggaa ttacttttat tgcaaactta 847020
aacacttcct gcccagccat cgttaaataa tgatcctgat tagatttact gattgccggg 847080
gcctttaatg cttctaaatt tcccgctgaa ttactgtagc tagcaaaaat accatcacca 847140
tttccaacta caagggctcc agccccatca ccaaacaaaa cacaagtatt gcgatctttg 847200
aaatccatta ttttggaaat ttcttcactt ccaatgacta aagcatattt atcttccatg 847260
ttttgtaata atgcctgggc taccgttaag gcatacacaa agccgctaca agcagcattt 847320
aaatcaaagc acattacttc ttgatcattc aaacctaatc tttcttgaat caaacaagca 847380
gtgctgggag taaaataatc gggtgtcatt gttgcacaga taatcaatcc aatcttactt 847440
ttatctattt tttcaactgc ctttaaagct gcttgatacc caagttctac gcaactttca 847500
ttttcagcaa tatgtcttct ttttatcccg gttctagaga cgatccactc atctgatgtt 847560
tcaaccactt tttcaaggtc gaaattatca agtacttttt gtggtgcata ataaccagtt 847620
gataatattt ttaatccact catataatct cctaatattt ttctttgata tcttcaaaga 847680
aatacaataa ctgttgtaat gatttaatca gtaactcatc atcaagaaca tgactatctt 847740
cacagacacg acttaccatc tcttcgtgaa agtctcgatg tactttgcaa acacgattgc 847800
ctttagctgt cagctctaca cgaataatgc gtcgatcatt atcatcttta cgacgtttta 847860
cgtatccctt agcttcgagc ttttttattg ctgtcgtaat tgttccatta gttaaagtcg 847920
cctgagaagc aattgttgac atcgtgggat ttgaaagcga actgattgca tcgataatat 847980
gcagttctga taaacttaaa tcttccactc catgtcctac catatattgg gtttcaatat 848040
ccaaaatttg attaaacagt cttacaaaca gttgattaat taattctcga tttaaaatat 848100
cgcgattagt cattcgtaat tcgacccatt tctctaaatt tattgtaacg tttatttact 848160
aatgatgttt ttgataattt catcaattct tcaagagtat ttcgaagata gattcttaaa 848220
cgtttgtata catattcgcg gttctttgta attccacctc gaggttcttt gatgatctta 848280
tcaatgatct tcatttcata taaatcattt gcagtcaatt tcattagctc tgcagcttca 848340
tgaactcttg aaccatcttt atctttccat aagattgatg caaagccttc tggtgataaa 848400
accgaataaa cactattttc aagcattacc atacgatctc caacacttag tgccaaagct 848460
ccaccactgc cgccttcacc gattacaatc acaataatag gcaccgtcag ctgtgacatt 848520
tccattagat tacgcgcaat tgcttcaccg attccatgtt tttcagcttt taaacccgga 848580
taagcacctg gtgtatctac aaatgtaaca attggtcgat taaatttttc cgcctgtttc 848640
atcaaacgca tcgctttacg atacccttct ggtgaagaca ttccaaaatt acagtgtaga 848700
ttttcctcta aagttcgtcc ttttaaatgt ccaattacag tacagggaat attattaaac 848760
attgctaatc caccgacaat tgaaccatca tctttgtaaa gacggtcccc atgtaattca 848820
ataaaatcat caaataaatt atcaatatat tcacggacat taggacggtc agctttacga 848880
gcaagataaa ctcgatcata agcactaata tcctgatatg cttcagcttc aatttttgct 848940
tttgtatttt ctaaatcttg aatttgtaaa gtgtggtcaa tctcttggtc atcctttaat 849000
tttaataact ctaattctat ttctttaatt tttatttctt tttcttgcag tgacattatt 849060
gcgcccccct gctatgcatt tttaataatt tgataatcgt ttcacgcatt ttagaacgtt 849120
ctacgatcat atcaataaat ccttgatctt gcataaactc ggttctttga aaaccttcgg 849180
gtaatttttg tttaattgtt gattcaatta ctcttggtcc cgcaaatccg attaatgctt 849240
taggttcccc aataataatg tccccaagca tggcaaaaga agcagtaact ccaccagtag 849300
taggatgagt aatatacgaa atatataaca atccggcttc atgatgtttg gctagagcag 849360
cactagtttt agccatttgc attagtgaaa taattccctc ttgcattcta gctcccccag 849420
aagttgtaaa aataatgatt ggacatttgc gttttgtcgc atgttcaatt gctctagtaa 849480
tcttttctcc gacagcacct gacatactcc ccattaaaaa acgagaatcc atcacacaaa 849540
caacaacttt tcttccatca attcttcctg tagcacaaac aaccgcttcg tcaagatttg 849600
ttgtttcttc taattttact aatttttctt tataaccagg aaacattaat ggatcatttg 849660
atttaatact tttatataat tctttatatt ttcccccatc atacaaaaga tttaatcgcg 849720
tgtatgcccg catctttaaa tgtgctccac atttaggaca aacataataa ctttctttca 849780
aatcttcact taaaatcgac tctccgcaag aatcacactt tgtatataaa ccatcgggta 849840
catcaattct ttttttatct tgcattttat tacgaataga tttaaataaa ttcaattttt 849900
cttttcgtgc cttaaataac tcttccattt attatcccac caacttatct aagttatttt 849960
caataaaact tgtatcaaaa tttcctttta catactctcc cgtatgtaaa atcaaatatt 850020
gtaattcttg gttagtatca attccgtcaa taactaattc agctaaaact ctacgcattc 850080
ttctaattgc ttctaagcga ttagaaccat gaacaataac tttagcaatc atggaatcat 850140
aatgtgatga aactttatac ccctgatata aagttgtatc aattctcacc cctaaacctc 850200
ctggtaaatg aacactatta acagttcccg gacacggtct gaatccctca cgtggatttt 850260
cagcattgat tcggcattca atcgcatgtc catttaaatg aatatcactt tgtttataag 850320
ttaatttttg atttgcggca attctaatct gttccctaat taaatctacc ccggtcacca 850380
tttcagtaat tggatgctca acttgaattc gagtattcat ttcaataaaa taataatttc 850440
catcttgatc taaaacatat tcaatcgttc ctgcattgcg ataacctgct cctttagccg 850500
ctttaactgc atcttccccc attttttgtc ggagcagcgg tgttaaggct ttacttggtg 850560
cctcttcaat catcttctga ttgcgtcgtt gaatagaaca atcgcgttct cctaaatgaa 850620
taacatttcc ataattatcg gctaaaattt gaaattcaat atgtttagga tttaaaatta 850680
atttttctaa atacatatca tcatcaccaa aacatgcttt agcttctgct ttagcagtta 850740
aataagcatc atcaaattct tcttcgctaa aggcttttcg cattccacga ccaccaccac 850800
ctgctgaggc tttaattaaa actggataac caatttgatt tgcaacttct ttagcttctt 850860
gtaaagtatt tacactccca tcactcccag gaactaccgg cacacctgct tcaatcattt 850920
tttgacgggc catactttta tttcccatca tatcaataac atcgccacta ggcccaataa 850980
aagttattcc acattcttct actaaacgag caaaagttga gttttctgat aaaaagccaa 851040
atcctggatg aattgcatca caacctagtg cagtcgctac acttaaaata tttttcatat 851100
ttaaataact atccgctgcc ttggcaggac ctatacatac cgcatgatca gccaattgca 851160
catgcaatga agtactatca acatttgaat aaacagcaac tgcttcaatt cctaattctt 851220
ggcatgttcg aattattctt accgcgattt cgccacggtt ggcaattaaa attcgcttaa 851280
acatcttaac tacccttcaa tgatcattaa cacttgatca aattcaacta aatcttcagt 851340
atttgccatg attgatgtta ctgttccatc aattggagct ttaatttcat tcattacctt 851400
cattgcttca acaatacaca acacctgtcc tgcttttact ttagtgccta cttctacata 851460
cggtttagca gttggtgaac tagatgcata ataaacccca acaattggtg atttaaccgg 851520
tgttccggtg attgctggtt cattagctgc tacttgctcc actggcgcta aagtaggcgt 851580
tggagcagaa actaccggtg tacttacaac atttaccggt gctactggcg ttttttctaa 851640
ttctaattta atatcatcta tctctacttt cattttaaaa acttctgagt tttcaaattc 851700
atttataagt tgctttacta aatctatttt cataaatact ctcctttatt ttgaatatca 851760
aagtaatttt ttaaaaaaat tattacccag ctattctggg taataaaaat cagcatttat 851820
tatgcatttt ctttgatata atctacgata tcttgaactg ttttaatttc agctgcttta 851880
tcatcaggga tttcaatatc aaattcttct tcaactgcca tgattaattc aactgcatct 851940
aatgaatctg catctaagtc ttcttttaag ttagcttcta aagttactgc atcttcatca 852000
cagcttaaag aatcaacaat tatttctttt actttttcaa attccacgtt atattcctcc 852060
tcgtgtatat tacggtcaca ttataacaaa atcaaaacat ttgtaaatag tttgatgttc 852120
aaaactttta tcgaagactg tcgaattaac ccaaaaccta gtaaaatcaa ggtgtttcaa 852180
gtaatatttt tttcgttttt tttatgtttt aatcgtcatt tttttatgtt atagtctttt 852240
ttaggagggc acaattaatg aaaatacccg aaataaaagc taagacaatc attcaaaaca 852300
aagccgataa aaatcatttt tggtttggtt ttgactacaa catgaatctc taccaaggat 852360
gtcatcacgg ttgtatttat tgtgacagtc gtagtgattg ttatcaaatc tcaaactttg 852420
atcaaattaa agtaaaacat aacgtactca ccctactttc taaagaactt tgttctaaaa 852480
aaagaaaagg ggtgattgca attggagcca tgtctgatcc ctataatcat tatgaacaac 852540
aattaaagat aactcatcaa gctttaaaaa taataaagca aaccaatttt ggtgtaatga 852600
taacgactaa aagtcatacg ctcattaacg atcttgaact cataaaacaa attaatgata 852660
aacaatctgt cctaatttgt atgaccatta cttgtggtga tgattcatta gcaaaattga 852720
tcgaaccaaa tgtttcaatt tcatcaaaac gatttgaaac aattaaacaa ttacgccaac 852780
acaatattta tgctggggtt ttaatgacac cgattttgcc atttattaac gatacccctg 852840
aaaatattcg agaaatcatc tatcgcgcac atttagccaa tgccagcttt gtttatccta 852900
tgtttggtgt gactttacga gatcatcaac gtgattattt ctatacgcag ctagatcatt 852960
tatttcccgg ctgtaaggaa cgctatataa aacaattcgg taatacttat ttatgcaaca 853020
gcccacgact ttatgaatta aaaaatatat ttattgaaga atgtcacaaa tataatatca 853080
tttataagat ggaagatatt ataaatggtt ataaacaaac tgcatcatcg gaacaattga 853140
gtttatttta aaaaatagtc cagaagatct tctggactat ttagcatgtt catatgtata 853200
attcattacc acttaataga taatactcat ctttttttag tatcaatgtt ttgatagtct 853260
aaacgtttat acaaattatc aatatattgg tgttttaaaa cctcttgaaa actatattta 853320
aaattcaaat caaatacaaa tactaaatgt ggtaaccaaa tatctaaatc attttgctga 853380
cagctgctta aaatcatttc atgattcaaa aatgactggt acactgctct cactaatcaa 853440
ttgtttttct atttcttctt ttcccttata ataaattgtt tctagcggga gagtagatta 853500
atttccagct tatcgatttt gttagcatca cggataatct ttgcatgcag taattcatga 853560
gtatctaatc ccattcaaat cacatattta ttgtgcttta tgattgcttt ataaataatt 853620
tgctcattat tataaatatc actaaatttt tcaatcaacc tatcttaaaa taataaagag 853680
acatcgaaat catattcact gacataagta ttaaattctt tatatgcata ctctattttt 853740
atcattaact tacctcaaaa aagtgatctt aattattaag atcactcttt tcttttaaat 853800
attcattagc atggttcatt atatttaaca tcttcttaaa agtatcacta ttttgataat 853860
taagtcgttt aactaatttt gtaatataat cttgttgata aacataatta caactatact 853920
gataattcaa atcaaatatc aaggccaaaa aggataccca gcgatccaag tcagttttac 853980
gagtggtact aagaattgat tcactattca taaatgtttc atatatcgat tcagtaatga 854040
tgtcattttc taaaatctct tgtccagcat ccaaaaatgc ttcgaacgtt tctaacaaac 854100
ctgttttaaa gatatcgatt ttgtcagcat cacgaattat tttacagtgg agcatctcat 854160
gttcacttaa tccctcagca attttatatt tattatgatt aaaaatagct ttgtagatca 854220
gtggataatc tttttgatca atatcaaatt tactaattaa attatcatca aataaaattt 854280
gaacacctaa taatgcatga tcaattgttt tactatcaat aaaacaatta taacgtttta 854340
attgttcaaa tctcccaata tcatgtaata atccaattaa tgatgctaag tctatttcat 854400
cttgatctaa cccgagactc actgcaacat tttttgaggc ctccataaca cgataagtat 854460
gttctatctt taaggcaact ttaggattat ctttatcata attcgctaca tattcatcaa 854520
acaatctttt agcatttttt aaatctatca tctaaccacc tccagctatc attatatgct 854580
ctttaacagc atttctctac tattttctaa atagtaattt ctatttttat atggttatgt 854640
tatattaata aacaaggatg tgattagatg aaattaagat taactactac taatgattta 854700
accgctgtca tgacaattat caatcaagct aaagtatatt ttaaagagca aggaatcaac 854760
caatggcaag atggttatcc tgatgaatta actattatta atgatattag ccgccatgaa 854820
gcttatgtgc ttgaagataa cggagaaata gtcgcaactg cgatgatctc taaagagctt 854880
gaacctagtt ataattatat agaagggaaa tggcttcaag ataatgcata cattgtagtt 854940
catcgcatcg cgatacgaaa tgatcaaaaa ggtaaaggct tggcaaaaat cattattgat 855000
gaaggattaa aactttatcc taaaaaacca agtatccgta tggatactca tgatgataat 855060
ctttcgatgc agcgtttctt gattaaatat ggatttgaat attgtggcac tatttattta 855120
gaaaataaag aaactcgacg agcatatgaa aaaattcttt aacctgcatt acaaagtgca 855180
ggttttattg ttcaataaaa tcaattaata cttgattaaa acgttctcgt tcatcataaa 855240
aaatcccatg tccactatat tcaaacttgc ataaaatcga atcttctata cattcatgca 855300
tgattaaagc aaacgaaaaa ggacaaattt tatcaagcac tccatgcatg attaaagtag 855360
tgaccttaat ctcaaacaaa tcttgataca catcttcatc tcgtaaagaa attgctgttt 855420
ggatcgttcc tattcctgat ccctttaaac aaattgatgt aaaccagttc ataaattcac 855480
tgccatgatt taatgcaaaa acattttgtc cgaaatcatg aaccatttta ggtcgattag 855540
tataacactg ctcaatcagt tgatttaccg catcgatact ttgtccttcg ggattatgaa 855600
ttgtacgagt atatgaaggc actgcagcac cagccaaaac tagtttactt actcgttctt 855660
ttccaaattt actcatataa cgaacacaaa tcgccccacc cattgaaaat cctactaatg 855720
tcacattatg gacatttaag gttattaaaa cactatgcag atctatcgct aattggtcat 855780
aatcatagcc cctgcccata acttgtgaca ttcctaatcc acgaatatca taactaatga 855840
tgcggtatcg acaatcgttt aaaatatctt tttgatattc atacatttct tggcaaattg 855900
gccagccatg cactaaaact actgtctttt gatgagctgg attaatatcc tctaccgcta 855960
atttggcatt atctgatgat tttagataaa acacataatc ccccctcatc atattctatg 856020
taagctcaat aatattataa ccttatttta attattaatt tttgtatacc agcagtcgat 856080
taagttaatc aatatttact atgattcgct atcattaatt ttgataaatt atattgtgat 856140
attggagtga gaatattaat atatatcatc agtgcaatta ttatctatgg gtatagttgt 856200
tattatttta ccagtactat cgctaatctt ttaattgcat taatagcctt atgagtattt 856260
ggtatattta tcatcggatt aattttctta aggaatgtcc gcataaaaaa taattatagt 856320
ggtctcttgt aagttgaaac attccttatt ctcagcttgt ttttaaatga ttttaatagc 856380
ttgagcgact ataaccccat tattcttttt actaacagaa atattactat gacatataat 856440
atttctgtta gtaacttgat aattacaata attttgacta ttatcttagt tattttcaat 856500
atttatatct ttaagtgtaa aaattatttc atttgtattc atatcttatt gtattcagca 856560
tatttttata tgaggtgaag aacatggata ctaaagtaaa taagccttac cccgaaataa 856620
aagtaactgt gccaaatgaa acttatggtt taatgatcct tgataatgtc ggtgggatga 856680
attctgaaac atctgcaatt tgtcaatata tttataacca tagtattgct ggcgaagatt 856740
ttttagaact aaaaaaaaca tttttaaata tttctatggt cgagatgcat catttagaca 856800
tcttcatgac ccttgcctta gaattaggtt tagacccccg ctggtggagc tgtctaaatg 856860
atcaatgtac ttattggtca ccatcatatt taaattatcc taattcacta gaggaagtac 856920
taaaaacagc aatagacgct gaatatcagg caattgataa gtatatgtat caagctagca 856980
tcatcaaaga tccctatatt gttgcgattt taaatcgaat cattgaagat gaagaactgc 857040
atatcaaggt tttaaaagaa tgggaaacta aattagttag ataatctaac taattagttt 857100
tccttctttt aataattgca ataattgtaa attttgcgcc gcactaccta cataattagt 857160
aattccatta agttttgcta aatgttgacg attttcaaaa cttgtatcaa cattaatttg 857220
ctgaagggct ccaactaaac tatctccaac ataattagga tttgacaaat agcttaccct 857280
accttcaatt acctggtcat tgacccagcc ttgatcatta cctattaaat aaggatttcg 857340
agtatttttt acaattcgag ttatctttcc aacattacga tatggccgta acggattaga 857400
agattcacta gttaaaaaga catagctaaa tcttactgta tcacctaatt tatattgttc 857460
cactgctgta tcaatatcaa aattattctt acctgcacgt ttaataatag ctggaaaatc 857520
agcataacaa taattcatat caacaattgt tggtacccct tgaacccatc cagtcgaact 857580
atattgccac atatcatacg gtttatcata atttaactca gcagcatagt tagcaaccca 857640
ccgtgtataa ttatcaaaaa tcggatccgt taatttagtg ttccaccagt atagtgaagc 857700
atacatccca acataatatc cattggcttc taattcatca gcaaatgttt tagcgatatt 857760
tgcaatcaca tcatttgatt gctttccagt cgtattatta tcttctaaat cataatacac 857820
tggatatgcc atcttatagt ttttcactag acgtaaaaca tgttgtgctt cccctctagc 857880
atcactacta tttttagcat atgaatataa gtaaacacca aacggtattc ctaatcgtgt 857940
acactcgtct gcatttcttt taaacaaacg atcatcttga tctgttcgat cttgaccaaa 858000
accacatcta agaattgcaa aatcaactcg atcttgaaca atttcccaat caattacccc 858060
ctgatattgt gagacatcaa ttccatgtgt cgtcattctt ccacctccat taataatata 858120
tgagcaattg tcaaaaatgt gtgactttct agactttttt atcattttaa tgcgaaacaa 858180
tgaatattat gttataatca cattggtatg gattaaatac gccatcttta aaactgaata 858240
taaaactaaa taatatatat aaattggagg tcgatgaaat gaaaaaagta ttcgtcactg 858300
ctttaggagt ctgtacaatg ctttcattag taactattcc cactcctgtt caggcaactg 858360
atttttccgg gcaagaagat aagtacatga aattatgctc atcttcaaat ctttcaacta 858420
ataacttgaa cacttgtaaa gaattcaata catacttgaa aaataaaaat aaagaattga 858480
aatctcaagt aagtgattca aaaagcaaag tatctgatac tcaaaatagt ttgaatagta 858540
tctcaagtga aattagtgca ttaaatgatc aaattgctga aaaacaaaaa gaaattgaat 858600
atttacaaac ttcaatttca aatttagaag caagtatagc taaaaaagaa gaagaagtaa 858660
aagaacgtat gtattcaatg caatcataca ataacaataa ttcatatatt gactttatct 858720
ttggggcttc tagcttcact gatatgtttg cccgaattga cagcgttaat gaaataacat 858780
cgtatgatga tgaattagtt gcacaactag ctgatgaaaa agaacaagta gaaacacaaa 858840
aagctacggt tgttactgcc aaagctaata ttgaaagtca aaaatcatca aagcaggcac 858900
tacaacaaga atatcaagct ctatttgaaa aacaaaacgc tgatttgatt gcgcaagaaa 858960
aagcagctgc tcaagcggcc gattcaagtc aaaaaatcac tgataatatc gctgcactat 859020
tagctgctac tgaaaaatca caagtttctg gcggaagcgt tgtttctggt gattctgcag 859080
ttggaaacgc aattgcacaa aaggctttaa ctcgcgttgg ttatatgtat gtatggggtg 859140
gatgtcacag catgtctgaa atcgctaatc caaaccacac tgcatttgac tgctcaggtt 859200
tagtcaactg ggcttattat caatcaggtg tcaacattgg ttctaataat accaaatcgc 859260
tagctagtaa aggggtatct gtttctcgta ataacatgca ggccggagat atcatcttat 859320
ttagcagtaa tggaagtacc agcggaattc accatgtcgg tatttatatc ggtggtggta 859380
acatggttca tgctccacaa acaggtaaac ctgttcaagt agcggatctt ggttattcat 859440
attggcaaaa agaatggtat gacgttcgta gattgtatta atacaattag atgagcaagc 859500
ttgctcatct tttttatcac atatatatga aattcataaa ttaatttcat tatttccata 859560
acaaatgtga tattttttag aaaattagct ttatatcctt agaaaaaatc taaattagta 859620
tttacttatt aagaaaaata taggataatt actatgtatc gaggtgattg tatgaaaata 859680
aaaaaagtta tatctacagc tttaacgctg acaatagtaa caagtgcatg ttattatgca 859740
gcccctgtgg cagccgatga atttgatggt aatgaaagta aatatatgac attatgctca 859800
tcttcgaatt tatctagtag taacaaatca acttgtgaag cattcaacaa gtatcttaaa 859860
actaaaaatt ctgaattaac taaaaaattg gccgaacaaa aagaggctgc tagtgacact 859920
aaaacaacac tagaaagcgt tcaaaaacaa ttagatgaag ttaataaaca aatcagcgat 859980
aaagaagctg aaattgagta tttaaataca actattgcca atcttcaagc aagtattgaa 860040
aagaatactc aattattaaa agatcgtatg tatgcaatgc aatcttatgc aaatgaaaat 860100
acatatatta actttatttt tggtgcaagc aacttcacgg aaatgttctc aagaatcgac 860160
ggttataacg aacttacaca aagtgataaa gagttgattg aagaacttaa taaacaaaga 860220
aaagaagttg aacaacaaca aactatttta gaagaagcta aagccacttt agttattcag 860280
caagaagaac aaaaaacatt aaaaacaaaa tatacagctt tgttagagga acaaaacaaa 860340
tcaattgcat ctactcaaaa cacgatttat gattatggtg aaatgactga aaccctggat 860400
gctgcaatta aaaaatttaa tgaagaagca tatgaaactc caactcctac accaccgcct 860460
ccaaaacctg ataatggtgg aaacaataat aattccggtg gtaacaacaa caataataac 860520
aacaacaata ataacaatag cgattctgga aataacaaca atggcggaaa caataataat 860580
gattctagca catcagataa tcttggtgaa aaaatctatg ctgctgctta tgctaaatta 860640
ggatcgcgtt attggtgggg agctcaaggt cccacatact ttgactgttc tggtttagta 860700
tattggtcat taaaacaagc aggtgttagt ggtggtcgag atactgctgc tggttactcc 860760
agaaaatggt cagctgtaag ttttgcaaac tctaaaactg gtgatttagt atgttttggt 860820
agtccagctt atcatattgg aatcattgtt gtaaacagcg atggttccag atcaatggtt 860880
catgccggtg gtggtgattc atcaacacac ggtgataatc caaaagctta tgttaaagta 860940
tcttcaattg aaccaggatc atattactat agtagaataa gtacaattag acgtgttagt 861000
aaataataga tattttaaag gacaaatttt gtagttcact acaatacttg tcctttttta 861060
ttttaggcga taattatcca aataatatat gagcgttatg ttatatttat atcctattta 861120
aaatttacta tgctataatt aaagttagaa aacaaaggag ggaaatgagc atgaaagcaa 861180
agataatatc cctctttcat tacttattag tctttttatt aataattttt aataccagct 861240
gtcaagctaa atcaataaat attgttgata caaataataa tgatcagatt gaactaaatt 861300
tttatggata taaaacggaa gcaattaatg ttgttgcaat cgaagaaatt ttacaagctt 861360
atatggataa aaatcccaat attaccatta cctatgaaag tgtgaaagga actgagtatt 861420
atgagatact aaaaaaacgt ttggcctcta ataactatga tgacattttt atgatcgatg 861480
aagataattt acagcaatta actaattata attattttga agatttatca aagctaaaaa 861540
caataaaaaa ctttaacaca aactcattgg aacaaatggt gcaaccagat aatacgatcc 861600
cctatattcc aacttctatt tcagcatttg gattatattg caatcttgat ttactagaaa 861660
aacatcatca gtcagttcct aaaaataatc aagaatttat ggctgtttgt caatatttta 861720
ttgagcaagg aattactccg atcatcgcta ataatgatat ttctctaaaa acaattgctc 861780
ttgctaaagg tctttatccc atctatcaat cacctgaaaa ggatagaata atcgcttcac 861840
taaatcaaga tcctagcatt ctttgtaatt atcttaaaga aggatatcaa tatgttaaac 861900
agttaatcga caataaattc attgatgcag ccacaacttt aaaaacagaa aaaactgcag 861960
acgatctaat acagtttgaa gaaaataaaa acccttttat gttaactggt gcctgggcct 862020
ctgttcgagt tgaaaaaagt tcaccagatt taaattttaa agtttaccct tatccaattt 862080
tagacgatgg agcaattcta gtttcaaata ttgatacccg tgtatgtatt aatgctaaag 862140
gtccacatat tactgaagca aaaaaattta ttgaatattt aagtcaagaa gatgtgatgt 862200
ggaaatttgt aaatagtcag tcctctttta gtcctctgaa agaacaacgt attgctgatg 862260
atcctaagat tcaagaatta agcccttatt taacctcaga gaaaacaatt ctaggtagtg 862320
attcaaatat aaatcttccc ctttggtcac ttacccatga aggaatcacc caattattaa 862380
caggaaacag tattgatagt gcattagaaa taatcaaaaa ttatgaacag tgaggatgat 862440
tccaatgaaa aataaaaaaa tatcgttaat gattgtcggg ggaattagtg ctgtgatttt 862500
tgttgttttt tccatgttca tttatgttaa ttatgttcaa gattctcttt gggataagtc 862560
aatcaatgat attttagaaa caacctctca ggaggaaaaa gcctttaatg tctatatgac 862620
taaagaaatg actaactccc aaaacatcct tactaatatt gcctatctac aaactaagat 862680
tccgcagtat ctccagcatc tatctaatcg tgaagaagct aaatatttat atatcgacta 862740
taccaatgac tgctactatg atgaaaatgg taattatccg ttaggtgatg aacagttgtt 862800
tcagcaaata aaagctgata ataattcaca aggattttta gagccctatc ttaattcaaa 862860
aacaggtatt aagacttttg caacttatgt aaaaacaagc gatagtcaaa gtgtcattgt 862920
caaagaaact caattaagtt ttattattga aaacttctca ctttcgtttt ataacgattt 862980
aggtttttca tatattgtta aagataatgg tgaaatttta attcgttcca aacatcgtaa 863040
ctcaaatcgt acttttaaaa acttatttga tttaatcgat ctgtctggta atgatgcaaa 863100
aaccattgaa tcatttaaag catctttatc taaaagagat aaaggtgttg ccttatttaa 863160
ttatcaagat agttccaatg tattttgcta tgttccatta caacaaaaca atcactggtt 863220
tattatttca attattccta ataatgtaat catgaagcag gccaataaca ttattatttc 863280
ctccataatt ttatgtagtg gtattgctgg tgcaatcagc tgtgttgttt tgctatatat 863340
ccgtgatagc cgtaaacaca aaagaatgtt agagaactta gctttttatg atcatttgac 863400
catgctctat aattatcaaa agtttaaaac agagggggaa aaattatttt tggaacgtaa 863460
tcatactctt cttgcagttc tgtatttaga tattaatgac tttaaaataa ttaatgaatt 863520
atatggttat aaatatggtg ataagatctt aacgcagctg gcaaatattt taaaaaaatt 863580
ggtcatagcc ccaggactta cgtgccgagt aaatgccgat aattttttaa tcatgcagtc 863640
atatcatgat agaaccgaac tggaaaactt atgccaagaa atcaatcaaa aattttgtaa 863700
tcttttagaa tcacttgata ataaaaataa tactatagtt aaaattggta tatgctgcta 863760
tgaagatgat caaacaatct caggtattga tggtctaatt gactgtagtc acctcgcttt 863820
aaatgcatat atacctggcc aaaccaataa ctattacttc tataattcta aaatgcatga 863880
tcaaatgatt agaaaagtag agattgaaaa taacatggag tccgctttac tgaataacga 863940
atttacattc tatctacaac caaagtatgc gccaaatgga caagtcatgt taggagctga 864000
agctctagtt cgttggcttg agccatcagg aaatctcatt atgcctggtg aattcattcc 864060
aatctttgaa caaaatggct ttattcttaa aatggatgaa tatatatttg aaagtgtttg 864120
taagtttctc tatcaacgaa ttatcgaaaa cctgccaaat gttcctatat cgattaatat 864180
ttctagatta catctttatc aagatgactt tattgaacgc tacagtaaaa taaaaaataa 864240
atatagttta cctgataaat tagttgaatt agaaataacc gaaaacattt tacttgataa 864300
tattgaaaga attagaaaca ttatcattga actacaaaat aatggcttta cttgttcaat 864360
cgacgatttt ggttcaggtt actcatcatt aaattcttta aaagacttac catttgaagt 864420
cataaaatta gaccggcttt tcttaatcaa cagttatgat attcaaagaa gtcaagaaat 864480
catcaaagct attgttgaaa tggctaaaac tattaatatt aaaacagttg ctgaaggtgt 864540
cgaaacccca agccaattgg aatttttaaa aatgattgat tgtgatatga tccaaggata 864600
tatcttttct aagccacgac caatcaaaga atttgaacaa ctgcttataa atcaagaaaa 864660
ataacttttt aattagattc ctatttttag agttgcagac tcgaaagtag gaatttttta 864720
acattttctt agatatgcac ccaaaaacag cgtattatct ttatttattg agttagcaat 864780
atctcgctaa atatcatata acaattattc tttccataga aacatttttt caaaaaacga 864840
tcaataatac tctttatcta ataatattct aaaatttgat agtacaaaga aaacttgttt 864900
tcaaaattat tatcccttca ttataattat aaaaggttta ctacatcata atatcatcaa 864960
atcaatctaa taaaatattc gttattcata tcaataccat ctttttcatc aaactgtata 865020
cttttctata actataacgt caataatttt taatatttat attaaatagt ctttaaaatt 865080
agcagctttt aaagaccaga tattttttat tttaattgaa aacgataaca ttgatattag 865140
agatttaata atttttattt tagtgctata atctacaaga aaagagggat agtgtgaagt 865200
atgtacatca atttttaatt attatgacaa tctcatttat tggggaattg ttgggattgt 865260
tattgccatt gccaataccg gcaagcgttt atggtttagc aataatgcta atttgtttat 865320
ttactagagt aattaaatta aatcaaatcg aggaagtagc tgattggctg atcttaatca 865380
tgcccgtttt atttgttcct tctgctgtta gtctaatcaa cgttggtaat gctattatta 865440
aagatctcct agttattgga attgtcactt taattagtac catcgttgtt atgatcgtta 865500
caggaaaagt tgcacaagta atcattgaac gaaaggagga taatgataat ggatagtttt 865560
ttgcttgaaa cagtatattt tgggattgtt atcagtctat tatcatattg gattgcagtt 865620
caaataagaa aattattgcc ctacccaatt tttaatcctt tattgatcag tgctgttatt 865680
tcaattggta tattaatcat ttttgatatt gattttgata catataataa gggagctcaa 865740
ttcattactt ttttattgac cccagctact gtttgtttgg cggtaccact ttataaacaa 865800
gtgcaaatat taattaaaca tttagatgct attttaatca gtttatttag tggttgtctt 865860
gccggaattg tttccatttt tataatgtgt ttaattatga aagccgatcc tgtaatttat 865920
tattcacttt taccaaaatc aattacaaca gcaatcgcaa ttggtgtttc tgataaacta 865980
ggcggtaatt caaccattac agttggaatt gttattatta ctggtatcct tggtgctatc 866040
attgctaaaa gtatttgtaa attatttaaa attaagcatc ctgttgcaat cggtttagcc 866100
cttggtaata gtgcccatgc gattggaaca tcaaaagctt tagaatttgg agaaattgaa 866160
ggagctatga gtagtttatc aattgttatt gctggattat taactgtaat cattgcacca 866220
ttaatggcaa atttattata aaaaataacc ctttattcaa ataaaatgat atgtactgga 866280
taatccatat caaaacgagt aaagggattt ctttttatta tatctgacta tatatctctg 866340
gactttctaa gcgctcaacc aaacgctgta atgattgctc aaaccgatca gtaaatggtt 866400
catcaaaata aagataacca ttttcatagt cctcatctac agctgtttca acaactacag 866460
taagactttg ataaacgcta ctaagatttt cttttatata ttttaattcc tgatgattgt 866520
attcttcaat aaaaatataa tgattacaaa cctctaatgc atatttaagt tcatcattaa 866580
aattatcttt aataatttca tgattaagaa ttccaacttg aaacccacga atctctaatt 866640
ctaaagcaaa ttcatttatc cacattatat tacttgtatt agttaataaa gtaatatttt 866700
tttctttatt ttttaaagtt agatttttta aatcaaaaaa aacttgaagt aaatgccgaa 866760
ccaaattaca ttcagtaatt atacttgtat gttcagctgt atatttcttt attttagggt 866820
gtgcacgtaa atcaattgct tttaaggctt gggaaagttc aaaatatcga tcgactaagt 866880
cctgttttgt aatattgtta gtaatgctat tgacgctaaa aaaatgataa ttagtatatg 866940
gtaaaatatc agtatcataa ccaaaagcca cttttgcttt aacccctttt tcatcccagc 867000
caataaacct tccaattcgt cttgctgctt gtcctgagac gattttaaca tatccaaatt 867060
tagccataat taatactcct ctttctttat aatttcttag cagcattaaa tattcatttt 867120
aataactatt ttcaatgccc cttattcgct tatataaaaa ttcatttgtt ggtactttta 867180
gtttatgctt tgatgccaaa gaaattactg ttccagcaaa catttcaact tcactgtaac 867240
gacgtacttt tgcatcttga gccattgatg gtaaacccag aggagccaaa gtcctaatta 867300
tctcaatata atgcttcaaa tccgtttcag ttagatcaac tccctcgtaa tgtgacaact 867360
caataatttc cttcattgct gcaatcaagg tatcatttgc ttcccctggc attaaagcac 867420
cactataatt ggtattatat gccatacaag tctgatttat cccaacattc aacatgaatt 867480
tagcccacat actatgtaaa atatcgcctt taacttcata attaattttt gcttgatcga 867540
agaagctagt aagcttatcc aacttatctt tttgcttgaa atcagtgatt cccaataaga 867600
gctgtccttc tttagtgtac tttagagatg ttccaaactt cattgcatcc attccctgag 867660
caaccgcata aattactttt tctctcccat agtattcact aataaccttt tcactgtcaa 867720
tcccatttaa aacagaaatt attattgtat ttttatcaac acatttttta atttccttta 867780
ttacttcttc taaagcagtc ccttttactg ctatgattat taaatcaaat ggaacggcat 867840
taaaatactc aactaaatta aataaaactt tctcaccatt tattgtaaat acagtttcct 867900
gatatgcttt tttccttttt tcatcaacta taaatgtcac tgcttctcta gtaatgtttt 867960
tgcaataaaa tctccatata acattcctaa agcacccatc ccaataattc caactcgttt 868020
gatcacaata atatcctcca taagaaaaaa gctgatcaat gaccagcttt tgcatcaagt 868080
ttcaattaat tatttagata attcagcgaa atatttgatt gttctaacca tgttagaagt 868140
atatgaattt tcattatcat accaagcaac tgtttgaact tcagtagttc cgttgtccat 868200
tggtttaacc atagtttgag ttgcatcaaa taatgaacca tagttaattc caataatatc 868260
agaagaaact aattgttctt cagtatatcc aaatgatgga gtagctgctg ctttcatagc 868320
tgcatttact tcttcaactg taacttcacc ttcaacaact gaagttaaga ttgtagttga 868380
tccagtagga acaggtacac gttgagcaga accaattaat tttccgttta attcagggat 868440
aactaatccg atagcttttg ctgcaccagt tgagttaggt acgatattta ctgcagctgc 868500
acgagctctt cttaagtcac cttttctatg aggtccgtct aataccattt ggtcacctgt 868560
gtaagcatgt actgttaaca tgataccaga tttaatttta gctaagttat ttaaagcgtt 868620
agccattggt gctaaacagt tagttgtaca agatgctgca gagatgattg tatcatcagc 868680
agttaagata ttttcgttta ctccgaatac aactgttggt aagtcatttc ctgctggtgc 868740
agagataaca acttttttag ctcctgcatc aatatgagct tgagatttag ctttagatac 868800
atagaaacca gtacattcta atactacatc tacaccgatt tcaccccaag gtaatttaga 868860
agcatctgct tcactataga ttttaatttc ttttccatca acagtgattg aattttcacc 868920
agcttcaact ttatcagcta atgcatatct accttgtgct gaatcatatt ttaataaatg 868980
tgctaacatt ttaggatcag ttaaatcgtt gattgctaca acttcatatc cttcagcacc 869040
aaacatttgt ctgaatgcaa gacgtccgat acgtccaaat ccgttaattg ctacttttac 869100
tgccattctt tatattcctc cttgaatgtt ctttatgctc atattatatt ccagaaaggc 869160
aagaaaagca actaatgtaa cgggtttcat tgaaaaaaat taaatatttc acaaaagatt 869220
cataaattta actttaatgg aacaaaatct aacattattc ttttataata taaatttagt 869280
gacttttaca agcctagttt taccgcaatc tttcttgcct tttataggct taaatgaata 869340
attattattt taattactat acttaaatgt ggaggtaaga taatgcattt agttcctaca 869400
gtaattgaaa aaacaaacca acgtgaatat gcttatgata tatattcacg actattagaa 869460
gaccggatca tcttattaac cggtactatt gatgataaga tgtccagcag tattgttggt 869520
cagcttctct atttagaatc attagataac aatgctgata tttttatgta tattaattcc 869580
ccaggtggca gtatcaatgc gggaatggca atctatgata caatgaactt tatcaaatgt 869640
gacgtttcaa caatcgtaat tgggatggct gctagtatgg ctgccttttt actcagtgcc 869700
ggagctaaag gtaagcgttg tagtttacct aatagtgaaa ttatgattca tcagccatta 869760
ggagcttttg aaggacaagc gagtgatatt gaaattagtg ccaaacgaat cttaaaacaa 869820
aaggaaaaat taaatttaat tcttagtaaa aatacaaatc agcccataga taaaattgtt 869880
atcgatactg atcgtgatca ctttttagaa cctgatgaag cgcttgaata cggcttaatt 869940
gatgaagtta tttaaaacga ccaacttatg aagtgaaccc caaaaaatga tgtgtaccca 870000
gttttctgga cacgtttaaa tttagtttta aaaaaattat gccatggatg ctaatctgta 870060
caaaacaggt ggcatccatt ttgttttttc tgtattcttt tattgcagta gaaaactatg 870120
aaaatgaata caattcattt tcatacccat aatagacttc attttttaat cggccaaaga 870180
aagtttccgt taccgaatta tcataacagt ttccttttct agacatcgat tgtattatac 870240
tgtgttcttt taatgaattg atataatgag catgttgata tttccatccc tgatctgagt 870300
ggaaaatcaa tccttcaagg atggaaaact tttcatatgc ctgagtcagc atatttgtaa 870360
tttgtttaag attaggatgc ggtgataaat cataggaaat aatctcattt gtaaacctat 870420
ctaatattgg agaaatataa cattttcccc atgcaaaatt gaattgagat acatcagtag 870480
tccatttttg taatggtcta ctcgcattaa aatttctatt aataatatta tctgctacat 870540
tccctttata agaatggtat ctctctttag gacgtttacc taataatccc atattatgca 870600
taagtcgtta cactctctta tgatttacca gataaccgcg atttagaagc tctctatgaa 870660
ctcgacgaac tccatagcgt ccccttattt tgatcaaaga tttcttttat cagtttcatc 870720
atctcatgcc tttagaagat gctttaatcg atatcctttt tcacgaattt ctttaacgat 870780
tgctgctctt aaacgtatta gttcttcttt ctcaggagga gtaagttcac ttgatattat 870840
agattttttc agaggctgct ccttactatg tcgtcccttc tttaaatcga gaccattata 870900
tccatatatt ttatatcgtt ttacccagtt tgacagttga ctgtgattaa tattagcact 870960
tattgcaaca cttttttgag attctccagc tagaaccctg gcaactaaag cgtatctttc 871020
ttccacagta tactcagtgc aggtggtagg atgttttaaa gcatctattc catgtaagtc 871080
agcgattttg acccatgtag taattccttt tctaaagttt ttttgtccaa ttccttctgg 871140
tgtttcatgc catcgaccat ttttatatag ttcaacacac ttcaacttaa atacataatc 871200
atatttcata taaaaaccct ccttactggt ttgcccagta aagagggtac gcatcacaaa 871260
taatggaggt tcattttatt atcagttagt cattttttaa tatataactg tctagatcaa 871320
ccaaatatat aaaaatcagc tatcctaaaa tataaaaaga agggaaacat atttcccttc 871380
taaatcaaac tattgtcttt aaaatctatt ttcatttaat aatttgtaca agctaaataa 871440
tcatactatt tttgaattac gatattgata tgctaataaa cctgttaata atagcattcc 871500
acctggtagc caaaatacta caaaatgata ccactttaat tttaatccct taaacttatt 871560
cagcatctta tatccccttt atcaatctac atataatata aggatataat cacatattgt 871620
caacataatt cggcataatt tagatttatt aagactttaa tttttttacc ataaatacca 871680
tgtcatcatt aatcttaaaa ccatttttct gataaaaatc agcactgtaa aattctcgtc 871740
ctgtcaacaa aattaaatta tcaacttcag gtaaacattc ttctaatgcc ttcatcattt 871800
tctttcctaa tccccttctt tgacaatgag gatcaatata aaaatcttca atcataaaat 871860
caagatcatt aacatatgtt attaatttcc cacaaacaac accagctatt ttgttatcta 871920
acatatacac aaaacacctt gtatattttc cgtcgtctaa ctgttcaatt cgctggtatg 871980
atctttcata actccatacc tcattccaag gaggattttt aaatgcttca accatcagtt 872040
tagcaatctc ttcatagtca tttttagtga cacttctaat catctaaaat ctctcgcttt 872100
ccacaaacac aataattact cttaaatcgt tctacagtat gaactacttc tttagttaaa 872160
aaatcaataa gtctttcatc caattgatgt tcttcaaaac tactttggtt aggataaatg 872220
agtttaccag gaaactttgt ttcaaagaaa attgtattta aaatcgtaat gctttcaaga 872280
taactcccta atgaagttaa atgctgattg tcactttgga acaattctaa ttcgggattt 872340
tgatggctta aacgattaat gacataaccc actggtattc catcaactaa attatccatc 872400
attacttgat gataaatatc tttggttgtt ttaaaatcat catcataatt ccgttggctc 872460
caaggaatca taatgtatgg cataacacca cagctacgtg ccaattcaat caatgcttta 872520
gcatcatgca atgttgcttc tttacttgga caaggctcat gtgctgcctg ttgaaaaata 872580
acaaaatcat atccttgttt taaagcgaac tgtaattcca ttgactctaa atgatcgtga 872640
aaggtaattg caggacgggc caacattgtc acttctaact tttcactact attgattcgc 872700
accatttctg gcatatcatt catatacgta tgcgaattcc caacaaataa tattttcatc 872760
ctaattccac ctactttcaa aggactactc ctttagtata gcttcaatta cgactactta 872820
gcaatctttt taaaagtaat tattgcttta aatagatccc catcgattgc aatattaaaa 872880
gtccccccct gtgcttcaac aaaactttta gctattgcta atcctaaacc actgccactt 872940
tcatgacgcg atttatcacc acgaacaaat ctttctgtaa tttcttgagg actaaaattc 873000
atctgctctt gtgaaatatt tttaaaaata atagtaatat cctcagtttc ctccgttaaa 873060
tcaacatata cacggctatt aaatagagca tatttagaaa tattagtgaa tagattctca 873120
aaaatacgat acgtcttatc accatctaat ttgaggatta tatcattatg tggataatta 873180
gtaataacag ttaattgatg cgcatctaat atttcactac attcagcatg cgcctgctca 873240
attaatgcaa caatattaag ttccattaaa tttaacttga tattaccact attaacttta 873300
ctaacttcaa ataaatcttc aattaaattc gttaaacgat tagaatactg atttaaatta 873360
tctaaatatt catgtcttgt ctctattggt aaattatcat cttgcaataa aacaatataa 873420
tttttaatac atgtcaatgg tgtttttaag tcatgagaaa cattacttac taattcattt 873480
ttcatattct gagacttagt ttcttcttta acagcagttt caaaaccaat tcgaatattt 873540
ttaaattcat catttaaagc attaaaaata cctaaatcac catctatctc tacatcaaaa 873600
ttacctttgc ttaattcttt tgttgcagtc aataatttat catagtcatc ttgcaccttc 873660
agcactttat ctttgaccca aaaaaatact aaaaatgcat aaataatagc taggaaatat 873720
ccaaaacccc aaaaagtaat catgatcata atgattgctg tattaatcaa aatatatttc 873780
atgattgttt gatttaacga ctttgataga tcaatatcgg caatttgatt aagtttattt 873840
ttgatactgc gtattccact accaattaac gtatcttctt ttaaataacg ccagaatcct 873900
cgagcaaaaa tgtactttaa ttggaagatt cctaatgaaa taactaaaag cgtcagtatc 873960
caaatcacaa aattaataac tataacgatg taatctacat acatgatgtc atatcttttt 874020
aataattcta aaagtgaatt attaagtgta taacccgtta cgatcataca gcccataacg 874080
ccaaaagtaa tcataagcgt taaaacagct agatttattt ctgctttcca tctctttact 874140
gacaaaaacg gattaacatc ttctacaatt ttaattggat aaaataagat aaataagact 874200
aatatagctg aacaacttaa taacgcaata gctgaaaaat aattatagtt ttcccatgaa 874260
ttaacatatt gtgaagcata tccatgactg gctggtgttt ctggaataat atatgtaatt 874320
tgaagattct taggaacatt aatcttgatt gcatttgtat caaacatcca gttgtcaata 874380
tatatagtat tttcaccatc ataatgtgca aatgagctta aaaggttagc aatattaaaa 874440
tatgatagtt tatcactact taaatcccca ttacatgaaa ctagaccatt ttgatcatag 874500
ctcgcctcag tatagaaact atatttactt tgatcatcat tagttgtaat tttttcacta 874560
tgttgagaaa tcatttgatt agtattagta ttaacagctt tataaataaa atctccatca 874620
ttattaaaca atgatgttat tccctttaaa taatcgtcaa aaacatctaa aaatatttgt 874680
cttgtctgtt catcaacact atcatcaaag cttactgctt caaaattaga atcaagggtc 874740
ttagccatcg caatagtaaa aagctgtaga tcatcttcta aaattcccgt taaattatca 874800
tcacgagggg tattttctct aacattatca tataaggata taacaacaac ggacattaat 874860
agtaatattg atgcaaaaat cacaccaaaa attcttttag cttttgtcat tttttacact 874920
cctttttcaa ttttatatcc tattccccaa actactttta aatattctgg ctttttagga 874980
ttagcttcta ttttctcacg caattttcgc acatgcacca taattgtctc agtatttatg 875040
gcttcttctt tccaaacagc ttcataaatc tcctcagctg aatagactct tcccggataa 875100
gacattaata attcaagtat ttgaaattct ttagccgtta aacgaacacc tcgatcatta 875160
acaaacactt ctttagtaaa cttatccagc tctaatccac ccacgactaa gcgctgttga 875220
ttattattaa gattacgatt ttcttttaaa gctaaaattt gattatatct tcgaagattc 875280
gaattaactc gagctatcaa ttccatcgcc tcaaacggct tagtaatata atcatcacca 875340
ccaatattaa gcccggttat tttatcaata tcttcagact ttgcacttaa gaaaataact 875400
ggaaaatcat agttttctcg tagttttagt accattgtaa ttccatccat aactggcatc 875460
ataatatcaa ccactgctaa atgtatttca tttgcttcga ttaatgctaa cccttcttca 875520
ccattactag cttgtaaaac attatatcct tgattcttca aaaaaactgt tactgtttct 875580
ctgattcctt tttcatcttc aacaattaaa attgtatgtt ccataatctt ctcccttttt 875640
ctaattagaa ttaactattt ttttataata aacggcaccg gtaattacta gtataacagt 875700
taccgcaaag attgaaacag ccaatacaat attgccgtct cttaatgctc ccattaaata 875760
tgtagatgtc acaatacttg gaattcttcc aatcgttgta agcaatagcc attgttttat 875820
atcaatatct gttaagctaa ctaaataagt cataatatct ttaggacttc caggaatcaa 875880
aaaaataata aatagccaaa acttactttt tttagaagaa aataattttt tcacttctgc 875940
aactttactt tgatcaaaca ttttatcaat gattgagtgt tgaaagattc gtgctaaata 876000
gtaaacaata atcgttccaa tcattgaccc gatcaaacaa acgattgttc cttgaaatga 876060
accaaaaata tatccactag ccagctccaa aggttctcca ggtaaaaatg ctaaaaagat 876120
ctgcagagca attaaagcaa tcattgctga aactttagta aaatatggca gtgtttcaat 876180
ctcataaata acatcattaa aatcgcagtt tctaaataaa tatattgtaa taaatgccat 876240
gaacaaaata attgatgaca tcatgagcaa atttgtcttt tttattgatt taagcataag 876300
tcgttccgcc tttctatact taaataataa aagactatcc taaaactaaa ctaacaataa 876360
ttcttaaaaa attctaaaca aaaagcaaaa ctttcgtttt gcttaattat aatcatcttc 876420
aatcgtagaa tcgacatcct cttctaattc ttctgtttct tcttcatcag cataaatatc 876480
attcatatca atatgaacat cactaaattt atgacgactt cttaaatccc aggcattttc 876540
accaaccgtg ataaaacgtc cgtctaaggt aatattagta taaaacaaag attctttatc 876600
ttctttttgt tcgtcatcaa atttcttcat ttgacatact tcttcccata atttgaaaaa 876660
attaactgct gatttctttt tagacattaa ttcatatgct acatcaacca tagacatatt 876720
ataatattta tccatactat ccattcttga ttatcctcct acatcttttc tggggcacta 876780
acaccgatta aatttaaagc attagccatt gtaattcttg tagcttcaac taaagctaat 876840
ctttgtccac ttaattcaag attatcttca tcgattacat aacattcatt ataaaaacta 876900
tggaataatt gtgcaagtct ttgaacataa tttgtaattt tgtgaggcgt acgattgatc 876960
gcactatcaa taattacgtt tctaaactca ttaatatgct ttactaattc aatttcttta 877020
ggattaacta ataaatcata cttatcacta taatcaatgt ttgctttagc agcctgtgct 877080
ttaatcgaac acattctagc atgagcgtat tgagcataat aaactggatt ttcattagac 877140
tttgatttag caagtccaat atcaaaatca aatggtgtat tagcagcttt agaaacaaag 877200
aaataacgtg tagcatcaac accaatttct tcgattaagt ctttaatagt aacagcattt 877260
ccagttcgtt ttgacatttt tactggttca ccattattca tcattctaac catttgaata 877320
atatcaatat ttaactggtc agcattataa cctaaagctt gaatagctgc tttcattcga 877380
ttaatataac catgatgatc agcccctaat aaatcaacta aatattcgta tccacgatct 877440
aatttattta gatgataagc aatatcaggc gtcaaatatg tatacgatcc atcactttta 877500
attaagaccc ggtctttatc atcaccaaat tcagttgatt tgaaccataa agccccttct 877560
tcttcatatg tataaccagc agcttttaat ttttcaattg ttggtacgac ccgatcattt 877620
tcatataatg atgtttcaga aaaccaaaca tcaaacgaca ctctaaattc atttaaaata 877680
tctttaatct tttgtaattc atattctgtt cctttatttc taaagaaagc aattgcttta 877740
ccttcatcca tttcaagata tttatcacca tcgatctctt tgatctttgt tgcaatatca 877800
ataatatctt taccatgata accatcttca ggcattgtaa catcttgtcc aaatgcttgt 877860
ttataacgag cgtatagaga taacgctaaa ttatgaattt gattccctgc atcattaata 877920
taatattcac gagtcacatc atagccagca gcactcataa ttcggcagat actatcaccc 877980
actgctgccc ctttagcatg tcctagatgt aaatcgccag ttggattagc tgaaacaaat 878040
tcaacattat atttagttcc ttgaccatat gttgtggtac catatgcttc tttttcttct 878100
aaaacttctt taatgattga tgtcattgca tcttttgcca agaataggtt aataaatccc 878160
ggtcccgcaa tctctacttt ttcaatattg gcattttctt tatctaaagc ctcaataatt 878220
gcctcagcaa tttggcgagg atttctcttt aataattttg ttagctgcat tgctagatta 878280
gttgaataat ccccatgtga tttatcttta ggaatttcaa ttgtaatact ttcttgatca 878340
tattcttcaa caaatccaca cgctattatt gcttgtttaa gcgccccttt taaagtcgct 878400
tcaattttat taattgccat cattgccctc ctatcttcta atcactatat cttaattaaa 878460
ttaccattaa accctcatga agtcaatgtt tttataacaa tggtgcaaat aatcttaaga 878520
ttgcttctag ccaccctcta aagcgccctt taacgacatc ttcaggggtc atttccttac 878580
tcacagcaat cgttttcaag aagtcctctt taatatcttt aattgctgga acatcataca 878640
tatagactcc acattcaaag tgcagataaa gactgcgata atccaaatta attgttccaa 878700
cagtagcaat tttatcatca caaacaaagt tcttagcatg aataaaccca ggagtatact 878760
cgtaaattcg tactccgcca tttacaagtg gttcatagta agagcgtgtt actttaaaga 878820
ccattttttt gtctggaatt ccaggtgtga tgatccttac atctactccc cggcgaacag 878880
ctaaacacaa agcattttta atttcatcat taatgattaa atagggcgta tcaatataaa 878940
tatatttttg tgcttgatta atcatattta aataaacgtt tttccccacc ggcttattat 879000
ccaatggtga atcgccgtat ggtaaaatat acccatttgg acttatttcg ggacatatat 879060
aatgacgagg atgatattta tcataatctt caaatgtatt taatgatgca ttccacgttg 879120
ttaggaacat cagtgttaaa ttccatacag cctcaccctt gatcattacc cccgtatctt 879180
tccaatgtcc atatttcact ttagcattaa tatactcatc agccagatta aaaccaccac 879240
taaaaccaac atttccatca atcaccgtaa ttttacgatg atcacgggta ttcattactg 879300
ccgaaataaa tggaacaaaa tgattaaatg ctatacactt gattccataa ctttccaatt 879360
tttgataata acgaaatggc agcattgtca aagagcccat atcatcatac ataaatcgta 879420
cttccacacc ctctttaact ttttgcttta atatcgttaa gactgtatta aacatctcac 879480
cttcttcaac aataaaatat tccataaaaa taaaatgttt tgctttagct aattctttca 879540
acaaatctgg atatgtatca tcacctaaag ggtaatattt aatctcacta ttattataaa 879600
taggaaaatt ttcttgaact aaataattag cttgtccttt tgcaatcaaa tcctcaattt 879660
gttcaaccat cttatttgga taaataaatg gtctaatagc ttcttcttga ttagcaaagg 879720
cttcttgaag ctttttagct ggctttttat taccaaaaac aacatacaac aaaccaccaa 879780
aaaccggaaa agataagatg ggaattaacc aaataatctt ataactgggg tcatcatcgt 879840
cattgttgat aatatataaa gttacgatca cacttaaaaa aataaaaact ccttttaata 879900
aggtcgcatc agtaaaaata tagcgcataa ataaagctag ccataatatc tgaacacata 879960
ttaaaataat cgatacaacg atccggtttg ataaaaactt tagtattttc atcttagttc 880020
tccaatatta aataattgag catgacatat acttgactaa tcaaattagt tccatcatat 880080
aattcatact ttattttcac attatccccg ttatcataac taattaatct agtttttaaa 880140
gcaattgctc catatggagt ttcatattga tttaaaatat cacgatctct tactaaatgc 880200
aaaacactag ccccattatg aagtttaact tcattttcac ttaattcaat ttttatttta 880260
ttttcatctt gataactgac tacaatttta tcatcaccta tctccagatg accagaacca 880320
tcatatttaa cagtttcttg atgttcttca tatttaaaaa tacttcgata atttacttta 880380
attatttttt tcattctatc accgtgcata ttataacaca aatccgtcaa gaatactttt 880440
ggtgatatga tgaaaaaatt agtaaaaata tttgtaacta ttttagcaag tttagccggc 880500
atacttctat cactatatgt tattgcatat tgcatggggg aaccggatct aaacaagaat 880560
cgttatttaa aattatacga tgataatcaa gaaatttatt atcagtcgat caacgactat 880620
accggtcatt atgtaacttt aaataatgtt agtaattatt ttaaagaaag tattgtagct 880680
attgaagatc aacgctttta tgaccatcgg gggtttgatc caattggaat catgagagcc 880740
ctcaaagtaa acttcacaaa tcaaaaaaaa tctcaaggag cgagtacgat aactcagcaa 880800
tatgcacgct tattgtactt aactaacgaa aaatcctggt cgcgaaaaat taaagaagct 880860
tttttgacaa tgcagttaga aacacgttta tcaaaagatg aaattctcga gggatatatt 880920
aataacgttt attttggtca tggaatttat ggtattgaaa atgctgcaca atatttttat 880980
ggtaaaagtg ctaaagaact agatttaaat gaaagcagta tgttggctgg agtagttaat 881040
ggcccaacct attactcacc cttaaatgat gctaaagcag ctcgaaaacg acagtcaatc 881100
gttttaaacg ctctaatcga ctgtaaggaa attaccgtaa ctcaaaaaca gcaggttctt 881160
gatagtgatc ttaatcttgc tgaaacgcat aaagtagatg ataatatggc taataattac 881220
tataaagata ccgttattga tgaactcgaa gaacttggtt actacaacaa tacatatttg 881280
aatcaaggtt taaatgtgta tacaagtttt aatcaagatt accaaaaagt agtggaaaaa 881340
agtgctagtg aatatactaa ggatagtaaa gtcgaaacct cgagtatcgt tgttgaacca 881400
tataccagta aaatccttgc tattatcggc ggtaaagact atgccagctc acaattcaat 881460
cgtgccactc aagctaatcg acaaatcggc agtacaatca aacctttgtt atactacctg 881520
gcgctagaaa acggtttcac tccggcaacc acatttttat gtgaacctac tacctttaaa 881580
cttgacgata acagcactta cagtcctagt aattttaacg ataaatatgc atataaagat 881640
gttacgttag ctcaagctat tgctgtatct gataatattt tcgccgttaa aacacatcta 881700
tttttaggaa ctgataactt agcttcatta atcaaaaaat ttggaatcaa ggacgtcaaa 881760
gcaaatgcct cactggcact tgggacttta aatacaaaca tatataatct tgccaatatg 881820
tataattgtc tcgctagtga aggaaaatac aatcatctct atacaattga aaaaattact 881880
aatgatgctg gtaaagtcct ttaccagcac gaacaagaag ataaacaatt gctggagcaa 881940
gatagttgtt tagaattatc acagctatta acatctacat ttaatagtac atttagtacc 882000
tatcttcaag caacaatggc ttcttatcaa cttgataata tcaacgcctg taaaactggt 882060
agtaccgatg ttgataacct ggctgtagct tataatccac aagtcctggt tgccagctgg 882120
gtcggctacg atgacaatcg taaaatggaa acagctgatg acaaaactgt tgctaaaaaa 882180
accgttatcg atgttttaaa ctataccaat gaaaacaaag atgttacatg gtatcagcca 882240
accgaagacc tacagcaaat tgcaatcaat ccactaaccg gtgattttga tgaaaatggt 882300
acagtctatt ggtttaaaaa agactaatcc cgaagtttac acttcgggat agaaaatctt 882360
atgatcattt ttatttttct tagaatttac aattgcccca acaatttctg atacttctgg 882420
taaaaaccgg agttcttcat caattaatat ttcaatttca ctgagttctt cagtatttcc 882480
ataataacga tagggaactt ggctttgatc atcacttaca acataataac gaggatcata 882540
gccttttttt tcataaaatg attcagctaa ttgtttttca tgttgatcga gcagatcatg 882600
ataaataaac aatcgtcgat ctaaaaagcg tgtacataaa tctttcaaaa tctcgtcatt 882660
gccttctttt aagactgtaa aataataaaa aacgatcccc tcatctaatt tagtataatc 882720
attttcatcg acatgtccat caagaaacgg ctttaaataa cgaatatctc caaaatcata 882780
accagctgca taaagatctt tcattctcct aaaaatacta attaatacct gttcataact 882840
ccgggctgtg gggtgataat aaacttgcca atacatatga tatctggcta aaatataatt 882900
ctcgattgct tgtacaccag aattcttaaa aacgatcttt ccatcacaaa cagccatcac 882960
tcgtaaaatt cgggataaat cgaattgccc ataagtagta ccactaaaat aagaatctct 883020
aagtaaataa tccatccgat cagcatcaag ttgactcgaa accatctgta ctaaaatttt 883080
attaggatgt gttttttcaa taacactact tactctatgt gaaaaaccat gatcaaattt 883140
ttctaaaaga tcatgtactt cggtctttcc gttaataatt ttaattgtat atgcttcgtg 883200
gtttaaatca aaggcatctt caaaacaatg cgaaaatgga ccatgaccaa tatcatggag 883260
taaagctgca cacattactg ttaacttatc ataatcattt aaataggctc caattgcact 883320
attaaaaatc atttttcgag caataaagta aacccctaaa gaatgacaaa aacgcgaatg 883380
ttccgcactt tgatagacct gatgcgtccc gcctaattgc ttgattctcc gaagtcgctg 883440
catttcatga ctattgatta aatctaatat caatggttga tctacatgaa tataattatg 883500
tactgcatca cgaaaaacct tactatctgt taatttcgtc tgttctaatc gatatgccgc 883560
ttgattcatc agtcttcctc ctcgtactcc tcaaaacgat atgtttattc tacatttggg 883620
tacttcttta tatcaacttt tgataaaaac atttctaaag aacgaataaa tattttttat 883680
catcatacat agcttgataa ataacaactt cctccaatgt ttcactatct aacccaatat 883740
tcataacata atatagtttg cctttgaaat gtcgatataa atgtcgagtc tttaattttc 883800
gttccacgtt ctcaccactt tttctatttt cattataata catcttaaaa gtttatgcta 883860
taattgagtc taggaggtat gacatatgta cattaaaatc aatgaagcaa caaactatat 883920
taagacccaa tatcatggaa aaattgattt agcaatcatt ctcggttcag gtctaggccc 883980
acttgcagat gaaattgaaa atcctatcga attagattat cgcgatatcc cccatttccc 884040
gatttctaat ctcattggac atgccggcaa gttaattatc ggtacattag aaaataaaac 884100
agtaattgcc atgaaaggac gttttcatta ttatgaaggc aatgacatgg atattgttac 884160
actgccaatt cgtgtattta aaagactggg aattgataat ttaattttaa ctaatgcttg 884220
cggaggaatc cgtgaagatt taaatcctgg acaaattatg ctgattaaag atcatattgg 884280
tttatttgcc ccaagcccac tacgtggtcc taatctcgat gaattcggcc ctcgttttaa 884340
agatatgagt gaagtctata atcgaaaatt aggaaaactt gctcatcaag ttgccgatga 884400
caataatatt agtttaaaag atggtgtcta tgcttttttt aaaggcccaa tgtatgaaac 884460
accagcagaa atattagcat atagagcctt aggtgctgat gcagtgggaa tgtccactgt 884520
accagaagcc attgttgctc gtcactgtga tatgaaaact ctgggaattt cgttgatcac 884580
taataaagcc gcaggacttt caaaccaaga attaaatcac caagaagttg tagaagcggc 884640
taataaagca gaaaaagacc tagttacttt agtaaaaggc attataaaaa attggtaaac 884700
taaaagcatc atactaaact gaccctatag aaaacacatt tatcgtgttt actctatagg 884760
gaacaattta aagatgcttt tttattttat ttgcacagta tttaattttc gattaacttc 884820
actaatgtct ttatcatcca tagcccgaag atacttaatt ggttgattgg aatcataaac 884880
atctatttga tcgaccccta ataacctatc tccatcttca ccgtaaatat atccttgtcc 884940
tgctaaatca atgtttgatt catcaaaaac agaaacaagc tcatatttgt ttggatcctt 885000
aaaaacatca tagtatctaa ctactgcttt cacgacaact gccttaccaa ccttttgatc 885060
atttacccta atatgatttc cttgataaaa atatactccc tccagacgat atccatccat 885120
agccttaact tgctgctgtg caaaatttgc cgcccattcc ttatcatatg ctattttttc 885180
ttgacaggct gtcattataa aaagaaatag taataaacaa ataaatttct ttaattgttg 885240
cattatcctc tcctccacaa gctattatat cataaaaata tttttttatt ttaaataatc 885300
tttatattat ctaagttcta atgatattta caaaatctat aaaaataata caaatcctaa 885360
taaatactag tcatttaacc gattaacgga ctaatcgtaa agctcattat ttttaataaa 885420
ccatgaaaaa atttcaagtc ttgaaaaaaa acacacgcta gaatgcgggt ttcaggcgat 885480
ttgttactta tttgttactt atttagtaca ttttaggacg tttttaaata caaaaaaaga 885540
acacaaaatc tttcccttct taaaaaatta ctgtgttctt tattatactt gtcttcatat 885600
ttttgactct actaactata tatttttgta tttgttataa atatggtaaa ctagtgatga 885660
aatcattgga aaaataaata ctacaattat ataatcttca aataattgca taaacatcgt 885720
cttacccatt tttaaataaa tatataaaat acccaaacag aaaaatatag ataacataga 885780
tgaaaaaatt ggtattatta ttttaatagt tttcaatttt gaatcaagtg tatcttgatt 885840
agatttcgaa tttttgcatt tttcctcaca tgttagtaaa tctacagatt ctttttttct 885900
tctataatta tcagctgtat ttaatagctg atttaaaata gataacttat aagatttgtt 885960
atattcggca ttataatcat tcattatttt tgttattttt tccataaatg aatccagttc 886020
attaaaatca tcatttttat ttaatctgct aattatttcc cttttttgac catataatga 886080
atctgtctgc tgtttaaacg tcttcattga tgcttcacaa ctttctttag ttacatcata 886140
aaggcgaact aaattattat agacagtatc ctgttttttt gattctaaat ttccaaaata 886200
atcataaaaa taagctgaat cattataaat atctattttt ataataacat cattaaaata 886260
ttgtttagcc tgagaataag gtaaagctaa agactcgcaa aaatcaataa aattttcagg 886320
ctttttcatt tacaaaaata ctccaccata tctgcatctg aaagtataga actaccgcta 886380
tgatttgcat ttttccatgg caattcatcg tgagtctcat ccactaatct ccaaacattc 886440
atgcttaatt tatcctttaa tatagatata attaaacatt tttcgtcttc tgtaatattt 886500
agttgtgagt ttattcctct aattgggctt cttccataga cattaaaagt gctccatatt 886560
ttttttatca caggcccata ttcccaacat tcaatattat ctaaaaatgc ctttttatta 886620
aattctttca tgaaatttcc ttgtatataa tacatcactt tttgtaattg taaattacta 886680
atatataaac cattttcttc tgcaagtgaa attacttttt ttgataattc taaagcatca 886740
tattttgatt tcatttcaca ctcccctttt cttattacat ctttatccac tttcatgata 886800
ccacatttgt aacatttttt gattaaaatt gcaataaatg ttacaaaaat aagtaatatg 886860
attcctttaa acaccaattt tcatccctta tttttatttt caactattaa tatatatata 886920
tgtaatattt ttttaatact tctattttat ccaaaaaaat gaaaaaaaaa cctagatcaa 886980
ttagacctag gcttaaactt tatatttctt ttattgatgc aaaaattctg gtaatcgttg 887040
cttataacac tatgagtaga aattatgatt aatatcgagt atacaagttg ataaaaaatg 887100
acaaataact ataattgata ttgtacaatt attgatcccc actataattc caatagttgt 887160
ataatagggt atggtcctcc tttcccctta gccataccca accaagagca caaaagagat 887220
atctcctcac tagagccttg tgctctttta tttaaaagtt taatacattt gcatattttg 887280
tataatgtag tagaatagat tgcgtacaaa tattattttt gtacaataga atattgttcc 887340
tctcccatta acaatattcg aaagtataca aagagtacaa gttcacctct cccgttttgg 887400
gcttgtgctc tttttatata aagtttattg aaaataatta cttattatta tatactttta 887460
ttaagcatag tacgtattcc aaaattatgc taaaaacaca gtgttcattc ccatgtcact 887520
gtgtttttct ttatacaaaa aagcctagat caatgtgtgt gacctaggct tgaattttat 887580
atatttattg tttacgtgta tatcgcgata cccattatta ataatactat gagatagccc 887640
catatacaaa agggtatact ctatccttgt gtttaaacag ttcccctgaa tatcttcagc 887700
atttattttt aagtatacct tttccataat ctttacattt tagttccttt taataaccag 887760
tcccatgtat tagatcctac tacaccatct tgaacaagac cacgatttct ttgaaacacg 887820
ataatagctt ctttagtctt tttgccaaag tccccatcaa caaccaaatt aaatcccaca 887880
ctgtttaatc gttcttgaat taatctagta ataccaccct tcgcaccttt ttttacagtt 887940
ggataactgg agaatccttg tctagcaatt tctgcattta atctatttaa ccagtcatcg 888000
acaggttgag aaggttctgg tgcaggggtt gatacagtag tgccataatc aatataggga 888060
cttttgccat gtttagtcca ttttctagat ttagatccat ttgaaacatt agcacaagtt 888120
gaaacttgaa caccattatc ccatttagga gtagcttcaa ctactttgcc attaccaata 888180
taaataccca tatgaccttt catccagacg atttcacctg aaacaatatt gctaaaatcc 888240
gtagacactc cgctacactt actaataata gtatcagcat tctgatccaa tacaccattc 888300
tttaaatatt taccattatc aggatagccc cataagattc cttttaacaa accagagcaa 888360
tcccactgtc ttttaccacc agatgtttta tttccgaaag ttcctaattt ataagcagta 888420
gctgtatttg ctactgcttt tactttatcc actaattgtg atgctgttaa tactgccata 888480
ttatttatcc tcctttaaat caattccttc gatttctgca cgaattttta agcatctaat 888540
ataattaccc atataccctt tttgctcttt taaaagttct aaagaacaac taggtctaaa 888600
gtttaaagtt ccagcttcat atttaacagt cattgcatct aatttatcat aacggatttt 888660
tgcttgaaaa tactcacctc taaatctctc tttataaccg ttactattca tcatttcgat 888720
agtttcattt aattccatgt taattatccc cactttcttt attaattaat ttatccgcca 888780
cttctaaacc tcttgttaaa atggatggta cgttataacc tgcttctaca agattttcta 888840
tgattgatct aatctcatta acagctaatg accctaatac aaaccatccg attaatgttg 888900
taatgccaag atcaattcct agtgtagtgc caatctctat aaataaaaca gatgcagcaa 888960
aagccacaag aatcataatc caatagccta atttctttaa gacacctagc catccttttt 889020
gcgaattggt tttattggcc aatttcgatt tcatacagcc agtaatccaa tcaataacat 889080
taaataataa gaacaaagca aataaaatcc agtgttctcc aaaaataaag cttaaaaaag 889140
cgactaccgc tccagtaatc gcattgtatg tgtccatgta attcatatta tttaaaacat 889200
tcattttttt cattttcctc accttcagtt taaattttat taagtacagc taatacatag 889260
ccttccttga taccttcatc attaataatc tgtttaatct gcgttaactg tgatttcgaa 889320
gtataactaa cttcttcttc gacagtttcg atttctctaa ataaaatata atcattctgc 889380
tcgtaatcat tttgttttat aattttgtaa tttgattcca aaagttcact aaatttactt 889440
gccgtaacgt ctaattcatg tgttttaatc ataatttcat gccgtccttt catctttaat 889500
ttttcgtgta ccataatgtc aatactacat cgtatctagt attaccgttg gtattgatgt 889560
aaacatctcc acccgtagtg acaaataaat cagtacttga atttccattc ataccactta 889620
ttttatcgtt cgctcgcatt gaaaattcat atcttatatt tctatcaaaa tttgcaatat 889680
tttctatttt tttaaaagca ttaatagtac ctaaattgta agatttttga tatatctttt 889740
tgccatctat ccagtattcg cccgtaaact gttcttctgt actatattta aaataaatgt 889800
cctttttctc aataggggct ggagggactg aataatttcc atttttcgta aatactggta 889860
attcttcacc attttttaat atttttccaa atatgttcaa gtcatactca atttgaaatt 889920
caccttcttt atcgcaatag cgtccccagc cgacaccgtt tttgtgaggg ggaatattaa 889980
gtataacttt accaatatct atatcgtgaa ttacagttac tgtatttcca acattatcag 890040
taatggaaac ttctacttca tgggtagtat ttaacgcata accactaaat acatatcctt 890100
gtccactgtt aaacgcagtt gatttacttg tattgttgat ttttatactt ttagttttta 890160
ttgcattccc agttataaca caataagtaa atgtaggctt aacataaatg taagtaccct 890220
tgattatatc tttagttccc gaactgtcgc atctgtatgt ttcaaaagtt aatgtaggca 890280
gtgtatacgc agtaaccgtg actttaaccg ttttacttgc tgttcttcct cgactatcag 890340
taatcgttgc ggtgaatgtt atatcaccgc ttttatcaac cacaccggtg gtatatgtat 890400
ttttatcacc actataactg taatctctac cactaatact gtaagtttta atagtacttc 890460
catatactcc tgatgccccg ttaattgtta atttaatgct ggattttcct tgcagataga 890520
gtgaaccaaa tggatttacc ggtgttgcag taatacttgt aaaagtcgga acaatattcg 890580
tcggtatttt aacagtacaa gtacaagtac tgcttcctat gttcgttcca ccattaaagg 890640
tatatgctcg aaacattatt gctgtactgt ccgcacctgt tacactattt aacaaactta 890700
gtggtggtgt ccacgtagct gatgtgctgt agtcagcacc tataccagtt tcaggaccac 890760
catttagact ataataaaga tggtgagtaa aattatctga ttttctatca aaataaatag 890820
ttaacgcact cccaaaagtt ccaccatcac atcgtactcc tgacactctt ggaattgtag 890880
ttaatgtatg tgtataaccc tgctcgcttg aactgaactg actgtgactt atccaaccag 890940
taacgcttat agcttttgaa ccgtcagcat catgactaat agtaacatcc catgtaccca 891000
aacgaatcgg tgttgatgta attttctgtc cagtacttat accagtactg tatactccgc 891060
cgtttatacg agcatatact gtacctgttc catttgtagt ataacctgtg tttgttcgcc 891120
atacatctat ccaaactcgt acaacagagg tgtttgaatt tatgtcatag ctcagctcct 891180
gactgttaac actgtagttt atatatttat tacttgttcc aaaagttgcc attcacacac 891240
ctcctaagtt aatgtcagac catcagtagc atcataattc cagctgaatg ttccgatatt 891300
taatttcgtc attacaatgg catattcaat gttaagctgt tggtttgaca gatatgctat 891360
tctgcttcca ttttgataga atcctaattc cgtattagat aatttaacag caaagggact 891420
attgcttgca cctagttcta atacaccatc ctgaaatcta gcccactgtg agatttcctc 891480
ttttgtggcc ataccagtta gattatcatt aatactgctt atactgtttg taatcaatga 891540
aattgaactt gcattttgga ctatctgact ggataactgc tctatcaaag ttgaattgtc 891600
agtagtagaa gtctgtagtt tttcaaccag tgtagtcagc gattctttaa gctggttgat 891660
cgcagaagta tattcagtgg taatattctg cttcatatca ttgatatcac cagcaaaatc 891720
attagtcact tcccatgtag taccgttcca gtattttaga agattatcag ttgtatcaaa 891780
ccataactta gttttatcac taggtgcagt agcactatga accgtaccat cgtcaccttt 891840
gtcaccctta tcacctttaa tcaaactcca tgtataatca ctggctgaag ttgattccgt 891900
aagggttgtc ttgttgtaag ctaaacctat gtatgtttta cccgatggat catcagacat 891960
attagcacca ctggcacttg ttgcatactt aacccatgta taggttgttt taccatctgt 892020
accctttggt ccctgaattc cagtatcacc tttctcacct ttgattaaag accatgtata 892080
atctgaataa ttactgcttt ctgttgcagt ggtcttatta tacgctaaac caatatatgc 892140
ttttccagtt gggctgtcac tcataccact tgtaggtgta tccgcatatt taagccatgt 892200
ataatactgc ttcccatcta ctcctttagg tccctgtacg ccctgtggtc cttctatttt 892260
aacccatgag tatttattaa aaactgcact gtcagcttca gaaaaatcca catatgttcc 892320
aatatattta cctggtgttt ctccattatt tgaggtaaaa gtttttccgt catcactgta 892380
cttaatatgt agatacgaag tttgtccatc gcttcccttc ggtccctgaa ttccttgttc 892440
tcctttgctt ccagtatctc ctttgatctt gctccattta tatgaaacat atgagctcgg 892500
agctgtattt gatgttgttg agcatgtacc aatataaaca gcattctcag cactgtcagt 892560
catcgggtta ccattagcgt tttgagagta tcttatatag aaataagaac ttactccatc 892620
cgctccagca acccccttaa ttccctgagg tccttgttca cctttgattt tagaccatgt 892680
ataactgtca acatttgtag gatcattaga attaaagtct acacactgtc caatataatc 892740
acctgctgtc tctccactgt ttgcagtaaa cgacttcccg ccatcattag aatattttat 892800
atggagataa gaagtcttgc catctacacc attagttccc ggtattcctt gtgtcccctg 892860
agctccctga attccctgaa atctcgccca tgtatatttt gttggatctg tactgtcggt 892920
ttcagtgtaa tcaacataag taccaatata aaccgacgga gtttccgtca tttgactaga 892980
gcttgtcgga ctggcaacac tgctatattt aatgtgaaaa tacgaagtct ttccactaga 893040
accatcattt cctttaggtc cagccggtcc ttgaattccc tgattacctt gtggaccctg 893100
aagtccctga agcccttgtg gaccagtatc gcctttatct ccggtaatga cgaatggaat 893160
tgttgttgag gtagtattat tactaaattt tgtcgtatct ttgcgccata gatactgccc 893220
atttgctcta accggttgag cagttatcca tccgctgtca ggtggtgtcg tactgctggc 893280
attaactgca aagtaaggtg tgatactaat cacactaaca ccatcatccc cagttggacc 893340
ttgcggtccc actgctccat cttttccatc actaccgtca gcaccgtcct tacccagtac 893400
atttaaacta aatgacgtaa acagtttaat acttgtgttt ttatacgata cataacagac 893460
atatgtaacc gccggattag ccttggtcat aatattttta cttacattca atattccatt 893520
gctaacattc tcgccattcg taagtccagt ttctgaactg ttgattatct ttttaaagac 893580
aatatcacaa ttacttaaat ccacatttaa taatccatct aaaactgctg gagtaatcgt 893640
aatgttgtta atttcccagt tagggctata agttccgtca gtatttaaaa tctgtactaa 893700
ctgtgaaccg gtaacatcaa gaaaactgtt gcctaaatta gcaatgtcat tattatcagt 893760
tatagttaca cttcctgtat ctaattcaat tccgcttata gaaactatac acttaaaatt 893820
agcacttaca tcaatatcat tgcctgtcaa tgtcactgat ttgccagttt taaatttttc 893880
ttcattttta taccattgaa actgtatatc agtctggtca ggtgtaatat cagtagtccc 893940
gttaacaact tgacaagaca ggacaattga tttattttgt tcatttaaaa cagttgcatc 894000
tgatatcata aaagctctat ataaagaagt atcaatatcc tctatcttag tattgatttc 894060
ttctatctta gtgttaattt cttcattagt aattgtaagc tgcccgactt tttcattaag 894120
cccttcttgc tcttttgcga tgacatccag tttaagtgat tcctgatctt gcgttatctg 894180
cagctttcgt atgcgtgttg tattgtttat tctcttgata acacgttctt catttttggt 894240
agttacggtt ccatctatat cagataatag aaaatttcca cccttaaatg tatttgataa 894300
atcaattacc ataaaattga attcatcatt ataattaatc aatttacctg gtaataaatt 894360
atcaatagaa atcatcttta cagattttac tgaatagaat gttaaaccat cgaactgttc 894420
gtatagagaa tctacaatca attgttcatc gagataaaga ttatttgcat taagaaacat 894480
cgtatttcct gtttcattac ctgcttcaag tggattcaat ccattctctg catatatacg 894540
agtcacttta taaacttcat tcttttcata atttgttaag gtatctgtgt ttgcaaatac 894600
atcctttgta acttttacaa attcaagcga attaatttcc tttgcaaaca cgttagcccc 894660
gcaaagttca gctatccagc ctagataact tcttataaca attgtattgt cataccacgc 894720
aacttcttta ttcaatacat aatcaggaat gttagttctg attatagaaa aaccagttag 894780
actttctatt tcatccaact ggtcttttat ttgtactgga tatgtaagtt ttgtatcata 894840
cgcaatatct agagaatagt tattgtcata cagttttagg ctcaacgatt tagtatactt 894900
ttcgggttga tcatatatct taaaatatct tttatctgaa gcattagttt cttgaatttc 894960
ccaatacact tcagtatcaa gattatcgag aattccatca tagttatcaa acttaagatt 895020
cagctggatt gttggaacat taccaataag ataaccctcc gcaaaagaac ttgaaatctt 895080
atagtcaagc agtcgacttg tcacatctaa gtttccgtat ttaattagca tgactacacc 895140
tcaatcaatg caaaagaaaa ggacttagct ttaagtccct ctttcgtcct aatgtaatta 895200
taacttttgt ttcccgcata catttttcta gtggcacgga ttccatgagt tggaataaat 895260
agttctgcgt caaactcagc aggagttacc gcattgagaa tattcatgat gtcgattgtt 895320
ggtgttatgt tccatgtcaa tgtgactttt aacatatttg atctaattct atttcttctt 895380
agaacacctg tagccactgg tctaacactt tcaccgtcca aatcctgaat ttcaacttta 895440
atatcagaag gtgtagacaa agctacacca ttcactttaa tcaatgcttc atttgccata 895500
tactccctcc tcttaataat caaacactgg tttaccagtt tgtacctcat attctttaat 895560
attatcaatt accatcttgg tcagtacctt cccattttcc aaaacaaaat taatgacata 895620
agttgctcca tttccactat ccccatcaaa agataatcta tctgctaatt tttcagcaat 895680
cagatcaagt ccctgggtat tacgtttcaa tggaattaca gcctcagtac ctgcctcacc 895740
aaaaatacct aaagttggtt tgtttaccac tgttccttcg gctagcaaag gaatttgtgg 895800
tacgcttatc gtgctaatcc agtcaaaagg tttaagtcct aaaatactta ctttttttat 895860
tgattttaat gcactgttta taccatcgaa tggaatttta attactttat tgattccttt 895920
aataattgca tttacaacag cctttaagcc atttagaata ccgtctttga taccatcgaa 895980
tacagcacct cctgtactaa atacattttt aactgctgtc catgcatcgc tgaatttgcc 896040
cttgaaccag tccacaatat ttccaaatgc atcagtaata ttgttccata cgcctttgaa 896100
aaactcccca gttctgctga aagcaccgca tatattgtcc catgcatgat cgaatatagt 896160
tccaaaccat tccgcaacat cagaaaatgc agttttaaca ttttcccact gctgcccaaa 896220
ccattcacct aaaggcgcaa atgtttcaca gatactatcc catgcattgc taaatatctt 896280
acaaaccttc tcccatgtat cactcatatt tagtgtaaag attccaacaa agaaatcagc 896340
taccacttga aatgcaccaa gaataatatc ggcaacggtt ttaataacag agccagcaat 896400
ttcaaatatc gtaataaacg ctgtctttat aaattcgaca ataggtttta gcattgtatt 896460
ccataacttt gataaagttt caataacagt attaatagcc ggcatccatc cctgaagaat 896520
atcgcacaca gcttgtattg ctattcctaa aacactgaca agaaaatccg caatcggggc 896580
aagaatgtta gtccaaaatg ctaaagcaat gcttgctata gcttctacta ctgttaaaaa 896640
tacatctgtt aataaattcc ccaatgggag cagcactgta ttaaaaagca ttaccagcgt 896700
atcaaaaatt ggtaaaaggc agcttgtata aaaattctga agtattccta ataaagcacc 896760
taccgcatca ttcacaagat ttctaaaaga ctcactagtc tgatataaat aaacaagtgc 896820
tgcggttaca gctgtaataa cacctacaat tgcaagcatt ggagtattta atccggtaag 896880
cataacactc aatgtttcaa ttaccccaac atccttgaat aaagcaaata atgcacctat 896940
attagtaaat aaatttttta ttgggcccgt taatgcggcc caatttttga tcacctcaaa 897000
agcaacaaag cccgctaaaa ctccagataa cagacttgta atgacaggag cattggtctt 897060
gagaaactct ttaagcctat tgacatagac catcacctta tcaacagtag cctcaatacc 897120
gctcgtatcc ggctcctcaa acgcactgcc ccagtcgatt ggatcaatgg catatccgcc 897180
acctccggta ccagcgccag agccaccact accagaacta gaatcactcg cactgattgt 897240
atttaattca tcaaacccgg ccaatgaacc taacgcctta gccgttttct tggcttgacc 897300
ttctgtaccc tttaatgcat tatttagtcc acctgtagaa gctgttgctg tttttgcagc 897360
gttactagca gaagtaaaac cattcgatgc ctgctgtcct gccgacttct tgccaaataa 897420
cctaccaaaa actgcactta caacattcgc aaatgtaatc agttttccaa taatcatatt 897480
caaaaactgt actacaggcg ttaatgcggc aatcaagccg tttccgataa tccccaaaag 897540
ctgtttaaat cgttcctgaa ggatacgaat ttgattagcc cagctgctgc ttgttcttgc 897600
gaaatcgcct tgaacaaagg ctaatctatc caaaacaaag ttatatctta aagttgtttg 897660
ctctgcctga ttcatatcac ttatattttt attaatacct tgtgacaatg cataagcctg 897720
gagatttgtt tgagtcatta caacacctag ctcttttaaa gtttctgtct cacctgtaaa 897780
aacagatttt aaacgcacat cagcaagatc ttgagatatg ttataaaatg atgcgacatc 897840
acctgttaaa cctgccaaag tgaccgccat atcactggct gcgttttcat ttataccggc 897900
acttttagcc atagtcatgt aagtgcccga tgttttcttg gcgcttaact cgctcatccc 897960
aaatgcttca agtgctgatt tagaaaactt ttcagctttc cacgccatgg agccaaacgc 898020
tacatctaca acgttctgca cttcagtaag atcacttgca acctgtaaag cctctttacc 898080
aagttttaac agtccagttc caaccgctaa tcctacaagt gctgatttta tacctgatat 898140
agctgatttg attttagatg tctgcgcagt aacattctgg gtagctgact tcatttgagt 898200
ttgaactttt gcaagttcat ctctaaactg ctttgtttca gcgttgatta ttacttttaa 898260
ttcttctact gtccttagtc atcagcccca atctgtttat tatggttata agcgaacctt 898320
tttctttttt ctttaaattc ctctaattcg tttatttctt tttgctcctc tgcttttttc 898380
ttttcttcct taaataagtc aggatagtaa tcccatattt gcttaatttc aacattgtct 898440
tctttttgag aaaataataa tccaattcct ctgatgattt ggtcagccag aatagagtta 898500
tctatagccc gttgtttttg tttcattatc tcttttcgat taaaagaatc aataatatcc 898560
ttgatttcat ctaaacttag ttcccaaaaa taaaaaggat ctatcccgca gtcaactgca 898620
tttgggtaaa tcccatttat taagtctgat atattagtta cagttgttct ttggcttcgt 898680
ccaatttctc gctcatcatt tctgccattg aaccagagaa aaaacccgac gcttgataaa 898740
tcgggaaaaa cacatctgtc atgaatgcag tttgtgatcc tccctcatcc acatattttt 898800
caaacatttc ttctacatcc ttatatttga taccgtggtg aaatttttgc atagcaccat 898860
gtgtaattgt aagcataatc tttaacgctg gaacaccatt atccaggacg ttaacaagat 898920
tagtcttaaa ctgttcttca agtttagtaa ttacacttgt tgtgagtttt aatttatact 898980
caactccatc gacttcccac gtagcccatg ggattctttt attttcttcc atagctgcct 899040
ccttatgcaa tttctgggtc agtgattgtc aatttacttt gaagtgcaat gtttaagtta 899100
aactcaataa caccattaac tccaccacca gttcttttaa cagaaacctg accatcaaat 899160
tcagttgtag ttccatcctt taatgtttct ttaaaagtag cgatctcccc actctcctcc 899220
aaagctctca tcaaacgata tggactgtct gttgatgtat tttcatattt aaatttatag 899280
gtgatatcac ctgcatcacc gatacccatt tcatactgtt taacggtatc atcaagatct 899340
gtattctcta ctttttcagg atcaacaccc atttcaggaa tttcttttaa tccttttaat 899400
tttgtataag tactttcagt agcagatttt ttcttatact ctaaagttgc tccatttgct 899460
aacatataaa tacctctctt tcattaattt ttatgatacg caaaaatttt atttgtatct 899520
acaattgctt catatctcat aagtttatgc ttcatgcccg aaggctcgcc aatatctgaa 899580
catgaaatac gtttaaaacc aaattcagca ataaccttat caatatcaac tgcagtcgat 899640
gaagtactct tattgctcca gatatcaatc ctaatgcgaa ttagtgatga agcttcacct 899700
tcatcggtaa cttcataaac acagttctct tcctcgcagt agctgactgc tggaaaattt 899760
gtgaaatcct gaggatacgt atcgctcaga ttatcaacaa ctttttcaag ctgctcaact 899820
atcttatctt taatattgat cattttttca tcaccttgac tatttccttt ccaatatatc 899880
tattcatctc tttagtaata tcttttttct gatcatgcag cgctggatag agatacggcc 899940
gtgccggcat accattagta cggtatccga taacttcacc accactttct acaacaccca 900000
agccataata ctcagcatca tcaacactca tagcatcagc aggtatcatc catccagttt 900060
gtgaatattt aggattaaca tttggagaaa tacccgcatg tttttcctga ccattgggac 900120
ctgttccaag ctcatagtaa atgccataat caagattagt gtaaacagta ctgcttgctc 900180
cactaggcct ctgttctgtt ctttccttga ttgacctacc taaattaccg ctcttagaat 900240
taaccaaaag acgtgcctgc ttttgtacaa gtagaccacc tcgctttact gatttcttta 900300
agatttcacc ctgaacttca ttagacatta aattaagctt ttttatgagt ttatccgcat 900360
tttgaaatgt catcttaatt tttccaactc aatgaattta aatttgggat agctcttaat 900420
tgaaaccacc ttatattccg gctcatcaat atttatacat atggcatcat tttcacttat 900480
atttaaatca ccataataat tcatgttaag catataggct agtcttagcc cataaagttc 900540
cgcttgtact tttccaccag ctggccagat taccgcttca ccttcaacag gatcaagata 900600
ttctaaagct gtattacgtt cagtatcttt ttttacgata tattttctaa gtttgaattt 900660
cttcatcttt cttcttagca tttaatcgcc tcctagcaac agcactaagt ctatatttat 900720
cgatacccga aagtatctca tcttcactgc gatagctgcg gtttactccg ccctcgctat 900780
gacttgactc cccggattca ccatctcgtt catatctcgc aactgcaaga tcaaacttga 900840
aatgttcaag ttctttcacc aatgacgggc gattagtttt ttcaagaaca gtttcctcag 900900
ctttatcaag aaaaagagaa accgatatat cgtcagtttc tcctgttact ttcttaaact 900960
cttcttcgat agtcattact gattaccttg agcatcctta atgattttac gaagttcatc 901020
acaattcagc ccgtcactat ccaaaccaag ttcttcagca gttttcttta aatcctccag 901080
cttcatttta gataaaggaa cttttttgtc cgtatcttga ttagactgtt ctgatacatc 901140
aattcttttg tagccaagct ttgcaaacct agaaaattct ttttcatcga taatgagttc 901200
tacattttct tttaaaacac gcatatcgac accccctatt cagttggttt tgcatctttg 901260
atatttacaa aaattgaatc ttctttattc tctaaagtcc ataattcatg gaatctacga 901320
tagtccattg cccatgcatt tgctttttga tttgtcaatg gatcgaagat tctcattaca 901380
tcctgtttag aaatagcgat tggtgttgct cttggaacaa taataaagtt tgcctccaac 901440
gctttagttc ctttcacata tccgccttgt tcttgacctg ttgttttacc atcatagatt 901500
gtaattgaag aatacattct gttttgtggt gtttcaatga ttggtacatg atcaactgca 901560
ggaacaattg tatcaatacc accttgagag aatgtaacag aagtaagttt ccccgccatt 901620
tctaactcta actgcagttt tgctgctgct gtcatatgaa ttactaaatc tccgttatac 901680
ccattatctc taatcttaga aattcctgtc tttaccttct ctaacattgt tgttttctct 901740
ggtgtatacc cgtattcaac catagttcct ttagtaattg cagttgtaat caattttgat 901800
aaacgatatg catcgatttc cggtactacc cacattcttt ggaattcacc cattactgta 901860
gatgctgttg ctacaaagtt tgtttcatca acatccatag gatccaattg aaacttacgc 901920
ccacgatctt gagtcattgt tcttgtttca taagacaagt taattgcacc ctgttgataa 901980
ccgttatcac gatcataggc tcctaacccc tgtaatgcaa ttttaggaat ctttacctca 902040
gcacctccgc tgtatcttac ctgaccggca tttgcttcca tccatcctgt caatgcttcc 902100
tgttgtgcta ctaaatctaa tgtctgttga aataaagtag ctgttgctaa tgtgttaatt 902160
ggcataaatt aatcatcctt tctatttgcc catcatattt ttataaataa gttcagcatc 902220
tgttgtttta tcatcagttg cttttttaat cggcttaccg cctttgatac ggtcctctac 902280
tgctttttct actgctgatt gaaatgcttt ttctactgtt tcaatcgatt tgttgcagct 902340
ctcagcatca gtaaaattta aaatttcggc caacgtaata ggaagccctt tatccgccaa 902400
ctgttcttta gcttgggcag tcaattctct acgagtaatt gctgcttctc tagtttccag 902460
atccttagca cgtttttgct cctgatactg ctttttctct ttttcactca tgctggccaa 902520
tttctcggcc tctgtctgtt gatcaacaag ctgtttttcc cacgacttac gctctttagc 902580
taatcgacct ttaataatat tatcgacttc atcctgagta aaagtcttgg tttgttcttg 902640
gctttcatca tttttaccat cttctttgcc tgaagtatct tgattatcac taccgccggc 902700
atcttcatca gcaaacaatt gaagatttag tggatacgct aatggccact ttctaaataa 902760
atctttactc ataaattcct ccattttaag tccgtatgac tatcccatct ttttttgtca 902820
taagtttttg gacataataa aggcgagatt tctctcgcca tgattaattt atttttcttt 902880
ctgcacttgt ttgatttcaa ctgcaacccc cgctccgact aactccttaa tgcgtttagg 902940
atcagcaact gtcattaagg ctccttcacg gtaagaaaga ccagtattct tatcgatcat 903000
attctttaca acttttagtt ttgccatcta accacctcct tttaggtaaa ataaaaacac 903060
gctacaagtc aattaacgtg ttttataaat ttataaatca aatatactgt gcatatagct 903120
atccaaatta ataatagaat tagtctaatc ttgaaatata actacatctt gtcattagct 903180
ccgttatttt catataactg tcgtctttag ccatataact caagttcctt tctcaatgca 903240
tcattataaa tttcaacaac ttcccatctt ccgccttcat attcatgatc ataagctgct 903300
ttagggcgag ccgtaggata aagataatct tcttcactgt catcaacaat gcgaagcatt 903360
ccgctatcaa caccaacaca atcgtaaact tgattgttag ttaaaccgtc aacaccaaat 903420
gacttaccaa tatatctaag ctttccatac aattccattt ttatttcttt atcaagttca 903480
cactgataaa ccattatagt tttcatatta atctctatcc tttcttaatt tcacttttgg 903540
ttcatattga tgcttatcat gttcatacca atgaacatca aatatatatt tatctgacgt 903600
aacttttgca acttttttag accaattatc aatgttcccg ccgtattttt ccgataatct 903660
ttttgctgct ctaagagttt tatcgctacc ttttcccgcg ataatatgtg tattcattaa 903720
agctgcccct gttgggataa atccctgctc accttgccat acataatcaa gatgtttatg 903780
cagtatccat ccgttatttg tcgctttgta taataatttc aagtctttcc aatccttacc 903840
atcattatac ttcaaatctt gaaattttgc gaacgtctcc ggcaactcta taccaccaat 903900
aacactctta taacgattaa attgttcacg atccttttta gcatttaaga ctttctttct 903960
aaatatttca acagtatcct taccgtattc cttttgctga tttctaagcc atttctgata 904020
gttttgatta gcactaacaa ttttatcttt acctgtgact ggatccctaa ctctacgctt 904080
catcttagct tcaattgcct tattaataac cggctcagtt gatgacctgc agtttggatg 904140
taatggtgga acatttaccc cctgcactgc tttatcaagc ggtatagttg aatggtcatg 904200
tgtttgacag attggagatg tcttcatatc atgcaccgca caaaaacgta ccatttcaat 904260
atcagcttct cgatacgctt ccatatctaa agcattacta ataaagtcac tctctgtaca 904320
aataagtctt ctggaattat aagcaccgac agcaaacttt tcaacgatcg tatcagccat 904380
ctgtttttca cttttaccag ttaacacacc catcagcatt tcttctttga ctgagtctgc 904440
taaattctgg gtattatccc agatacgctc gctatagttt ttaccactcc atttagaatt 904500
aagtaattta tcggtaacct ctggatcaat attttcaaag ctaaaggcta tactggttct 904560
ttcatggaga ttatagattg agttaaaata agaatcatat gctacatcaa tatacgtgag 904620
tgtattgact tctttttcac gcttgtagac ttctctcatc atcacatcga gattcttctg 904680
tgagtcctga agcttattga ttctgtatcg atacgctgga gcttctagtt ctttaagaag 904740
ttcttttctt tcctcacctt tagctcctgc ctttaatctt ttaagcatct gatcatatga 904800
agttggatca gttaaatcat ttaacagagc cttggcttca gcctcactta aactatgctt 904860
tttcctgtat ttatcaaaaa caccctggat ctgttcatta aaataataac aggatttttg 904920
ataaagcttt gccagttcct gacttgaggc ttctgcgatt tccatagctc tttgaatatg 904980
ttcagcctgt ctattacgcc agtagttact cactctaata cctcaataag aaacttcata 905040
aatttgttaa gcagctttat tattgggagc agaatctttt ttagctgttt atttattttt 905100
gtttttatct tccccatcag cttcttcatc atcttcaccc cctgagttgt taaacggtac 905160
attatctgct acaccaaaca ttttttgctg acgttccact gctttgtcgt tctcttcatc 905220
aactttttta atttcagttt gggcatcttc aacaaaatca agctgattca acaatgtttc 905280
ctgtgatacg aaacctttta aattagttat aatttgagac agctccaaca agttcttagg 905340
cagtcctctt gaaaaagttg gaatgattgc agttggatta atcgaaatcg ctttaagatt 905400
aagataatta caatacaatg ttatacgctg tttaagtgcc tttttataat aacgctcttt 905460
agttttagtt atcatctcaa gaccaagtaa cttatattcc attgccacac ctgaactgtt 905520
gccaacaaag ttttcatcag taagattagg aacatggctg aatgtataaa tatcttcttt 905580
aatagctttt cttaatactt ccattcccga ttcatcaaaa gttctagcaa tgtattctgc 905640
ttttgcatca agcggtaact caagtaaacc attttcttta agtatcttaa ctacctcact 905700
gacttcttct tcatcatcgc ccatcaaagc cccataaact acaagaagcg cttcaacaaa 905760
ctgttctttg tcatttacgc ggtcactcat caacgtgttg taagcgtcaa ttaaactaat 905820
ctgttgttca aaatcaccaa ctccattttt attatttaga atctgaataa tcgggacatc 905880
acctaaaaaa tgttcttttg gttcttcatc tacataaaca ttattttcat aagttccttc 905940
aagcagcagc tcatagatat aattttctgt tccaacagta gccttgtatt tgtactttcc 906000
ggtaacagca tctttaaagc gatagtaata aaccccaaaa agaatatttt cttcaatagt 906060
atcatcacat actagaaatg tatgttccgg ttctagattt tttgatactg gtgttgtctc 906120
attttcttta acatagacat actcatacgc aacacctgca acactcatat caagcgcatt 906180
gtcatgatca acatcgtcaa catcagccaa atcaaatgcg tctgtaagtt tatcaatatt 906240
cattttctta tcacttgtag aaaatgatat agccgagctt aaaaagtaac ccgtcgcagt 906300
atcgcttata tcctttgcgt gattacatac aactttatta ttactggaac cctttatttt 906360
tttagttcgc ccttgaacct tatgtttacc atcataatag cgctgatttt ttctaatttt 906420
agatgccacg ctagaatgct tacgaattaa atccctaatc atcgttttat ttagatttgt 906480
ttcatcataa tcattagcat cgattgtaaa atttttcatc agctacctcc ttgatttgta 906540
tatttagagc ggtttttacc tgctcttgct ttatttctaa taacatctgt ttcacatcca 906600
taacgagctg catcaatcgt atgattattc ttatcaggaa attcaccttt taagtttccc 906660
tccctatcct tttcaatttc atagtcatta aactctctag cagcgttagg acatcgtgtg 906720
gggtctataa ttatctgttc tagatcctga agccatttaa tcccgttttc tacactgtca 906780
ggccctttct ttgcaccaac gatatttaat cccaacaact tgaattcgtt aattgtacga 906840
ggttcagcac tatctgctgt aactaatttg tttaaaggat ttagtttttt tattttcttt 906900
actgctttct tgtttgaaag acgtgtacca taaacctcac caaaaataaa aagacgtctt 906960
ctcgtcttgt cataattcat ttttaaataa gctaatggat caccggcata accaaaatca 907020
agtccgttct tcaaacgatc aaatactgca atctcatcat cactgatttc tctaatatca 907080
agattagtga acacttcacc gccagtgccc gtaacttctc caagataatc atgattgtac 907140
ttttcttcat taataacctt taaatgctcc gcttcaataa gaaactgctc gccaagccac 907200
tctctcggcg cctgaagata agtagtatga cttatgtaag tatctggtct tttgataagg 907260
acttgcttat tacaccagtt tctttgactt tcaggaggat taaacgagta gaatacacaa 907320
tattcaggac caccacgcaa aagagactga ttaatattcc tgatcttatc gtaggattca 907380
aactcatcac attcttcata ccatacatat ttcacatatc cgacaaatac ctttgtagat 907440
ttaagtttct ttgggttatc agcacccttg aataaaataa cctgtcctgt tggcttatat 907500
gtcatttgta gtttagattc aggtatttcc caatcctcct gagcgttaag catataaata 907560
ccccatttga tctgttcata tactgaacct ctcaaagtat cctttaccct tctaataaca 907620
actgcattag acattaggcc attttgtgca tctctcataa tgcctaaagg aatttcaatt 907680
cctataaatg atgatttaag agaccctcga ccacctttta accagtaatg ggtatattcg 907740
cactccttaa tcagtttatg cacatcccaa aacgcaggac caattattga cttcaaacta 907800
acttttttag ccatctatat catcaactat catcgttttg ccattggaag taacatcaac 907860
cttttcagtc cacattccat aacgtctccc taatagttca gcagccctta gactttcctt 907920
ttcatcaggc ggtttctcaa taacctcctg catgccgtca ccgcacatgg ccagtacact 907980
cgaagttgat tcaccacgca ttactgaagt tagatattcc atgacttcct gttgtttagc 908040
aacacgttta ctggcgattt catccagacg ctgctgaata taatcccaga tttctttttt 908100
cttcaaaagt ttatttgctc taactgcagc agcattatcg ctcttgatat tagaataggc 908160
agctttatat gccctggtgc cgtttagatc aatcaaatat tcatctgcaa atatcttttg 908220
tttttcggtc ataaacgaca cctcactttc ttaaattaaa ttattttttc ttttccaatc 908280
ttcatagatt ccaagttttt tgtacttctt ttttaatttt cttggaagtc ttgacttcat 908340
tgaagttgta gttgttcttc ctaaagcatt aacaaacttt gccaacgatt ccgcaaatat 908400
ttgaaaactt tcaccgatac cttcaagaaa aagattaagt ccttttgata ttttttctgc 908460
tggttccata ttttcttcct cctcttaaac aaaaaaacct ctgcactgca aaggttacaa 908520
tattcaattt ggttgcagga ggtggaattg caccaccaac tccaggaaag gaccctggta 908580
agctgctact tgctatatcc tgccataata aaaggcactg cgtgaggagt gccattattt 908640
ttctaaatca ttccattcat tgtatacctt aattaaggcc ttatatggtg aagataatga 908700
attaagttta tattcaaact gctcatcttc aactatgtct tttatacatt tatgatactg 908760
ctttttaaat ctttctttat ctactttatc atctagatat tttgaacacg cactatcata 908820
ggtgtttaaa tattcttctt ttgcagcctt aattgctata ctatatcttt cactattgtc 908880
attcgctagc attaaatcag taagacgata tttactttga gctatgcttt gttcaatggt 908940
taattctatc tgaccttgac tgtttttatt ttgtttgtgt gtttgatata aagcaaacac 909000
agatataatt attgcaatta tagctaatgt tgcgcttacc tgatcattgg tcattatctt 909060
ctgttcctct aatcatctgt aaaaagtcag tttcatccct actatctctc ttctcataat 909120
ttccctggta gacatcaaaa tcctggttac tgtactttat ctctggctca tactttggtt 909180
gcttttgttc ttgttctcct ggtttgaatg gtttcttttc attcataatt ctttcctccc 909240
gttattatga tactcaatta taccacaata tccaacataa agcgacacca caaatattaa 909300
tgaaaggagg cattaaatga atggcgtatc agcaccaggt gatgccgctt tatctgaaga 909360
caaaaaaagc tctgggagaa tgagcttttt catatttgta taatcaaggg gaagtataag 909420
aaacacgaat caaccaaaaa gaaattaatc atctgtgtgt cttaaccaaa agaccacatt 909480
aacataataa cacctatttc actgccatac catgacacgg actgacaact ttattaaatt 909540
tcaagattat ttatagcatt tcgacgatag cgatacacat tacgctctga aaaacccatt 909600
tttttagcga tttcgtcata ctgcattaag tgaatatatg catatttcaa caccagacgc 909660
tcctggatgt ttttcaaagt atcgatcgta tgctctatct tttccatttc attaaatatt 909720
gcttcttttt ttgcatatag ttgttcaatt gattgtcttg ttcctaaagc tggaccatag 909780
cttatagctt ttatccccat tatttgtcca tcaacatatg taagctgatc taacttatcc 909840
ctataggatt ttaaatactg taccctttcg ttgtagtcca ttcattctcc tcctacagca 909900
tttctttaag tttaacttcc agcttgcgta tatacaatac gactgtgtcc ttagcacttt 909960
tgcatccttc aagcgaatca agctgctggt aacgatccaa cagctccttc atgagttctt 910020
gtttagtcat ttctaaatcc tccttatttt gtaacagtat ctgttagaag attaactgcc 910080
tttaatacac tctcaagtgt actgctgtac tctttttcat tttcacgatc agctcttaac 910140
atcttatttt cacagattaa atcatcaaga cgttttttta actcaataca ttcgtgctca 910200
tagttatgcg ccggttttct agattcagct tcaccaagct tattaatctc actatacaca 910260
gcatcaacag cttcatccca gcctttactg tattcgtcgg atgcgtcggt accgccaaga 910320
ccggcaacaa tttttaaaat ttcacttaat tctactttca tttactcctc caatttcata 910380
aaacatagcc agtgtgtctt agctgcttta ccgctcttgt gaccaaacaa cggctcagca 910440
tccaatacac ttaatatttt ctttaaatca atttgtatct cgttccattt aaatacaaga 910500
acaccaccac acttcagaac tctcatgcat tcatcaaatc caaactttag atcatcttcc 910560
cagtatttac ctaactgacc gtattgagct ttcataattg attttttccc cgcccatctt 910620
aaatgaggag gatcgaagac aaccagatta aaacgattat cttcgaacgg gatacttcta 910680
aaatccgcta ttacatcagg atgcactgca atgtgtttat cataaacatc atattcttca 910740
tcacgaatat ccatataaat agtattctta tgatgcttat tgaaccagaa tatcttactt 910800
ccgcagcata catcaagtat cattttttcc tgttccatac gctattcctc ctatacgtac 910860
aatcttaact tttattaacg tgttactatt ctccttctct catccagcgc aatcgaaaca 910920
taggtttctg aatctttcta tcgcagtagt cactgacggt ctgccggctg atatacaagt 910980
cattagctgc ttccctggtg cctttgtaaa tgcgattgtt atcataacag taaatcaacc 911040
tacgaatact tgttcgacca ccgtaaagct cacctaattc ctttcttgta acaattttaa 911100
gattcactaa agcattatca ccatagcact tatttctatg agtaactgca tgaccatcag 911160
gcacgagacc gttaaatgct tcccatacaa cataactcac tttagtttcc ttacaatgta 911220
tttttataag catataacat gaaccgcttc tgttcttttt cacccaagaa tttaataatc 911280
gctctttccc attcttgtag attcttttaa cacgtccata catagaagca aaatatggtg 911340
tgtcgcgata ctgtttccat atctcgtctt tcagatcttc aatcatttcc tatttcctcc 911400
tcggttaatt atgtttcctt gatctttatt ccgtaacgct cagctagtaa tcttttcttc 911460
aaacgatata ccggtgtctt aacccctttg acatcttcaa caatttctac atcattttca 911520
acataaacaa aatcagcaat atattttatt tcacgaccat aacagctctt atcaacaagt 911580
acaaatggaa cctggagctg gagattttcg ataagcccag ctctttccat ctgttttagt 911640
tgaatatacc gtttagcctc ttttttgctg tcaaacttga catcatcaag aacagtttta 911700
accgcatgat atttgcttcg tttaattttt ttctgctcat gttgttcagg ttgaggacta 911760
tatttccgtc catttgggta atcaaccatt aaaattggat atcctcctcc atgatgtcgt 911820
atgtattaac atcttccata aaatcactcg gacttgacga tccattatga aaataattat 911880
cgttggccat ctgctgaact ttttgagtat ccataggtgc ctcattttga tttctagtat 911940
caaggaactg cacgctatcg catctaacct caacaacaaa tactgtttta ccgtctttat 912000
catcgtatgt tcgggtttga atttttcctt caacaccgac taagcttccc ttagaacaat 912060
atctttcaac attttcagca ggtttgcgcc atacaacaca attaataaaa tctgcttgtc 912120
gttgaccatc tccgcttgta aaattacgat ttaccgctaa agtaaacgag gtaaccgcgt 912180
cgccttgttg agttcttcta agttcaggat ttctagtcat tcgtcctaca agaactactc 912240
gattaatcat cttcagttac ctccttgcgt gatagaataa cgcatattct tgtttcagta 912300
gttggaatga agccaaccac ttcataatca ccatccaact gtaaaactgt gtttttgtct 912360
ttatgtttta caataagagc attttcttta ttcgccatta ttttcctcct attcaaactc 912420
tgctaaaaat tcatccagtt catcaagatc aacttcttca tcaaaaactg gtgtgttagt 912480
atcttccgct tcaggcagat acgagtattt gagattttta ttcatggcac ttttgaaata 912540
tgccatacgg ttatcaatct gcttgtcctt catcagtcca agaacgtaat cagctttaac 912600
actcacatca acggcatcat actcagcaag atattcacga atgatttcat caaagatttc 912660
tgtttcgttt tcagcaataa gatttttaaa taaaagtctt tcggtcaggt aatgaatttt 912720
taattcaggc acgcaagtgc ttttatcttt tatcttatat cttttatctt ctattgttat 912780
atctttcttt agttgttgcc ctttgtttgc cttttgtttg ccctccgctt gcccctcgtt 912840
tgccattgta tctatcaatt cgtttgcctt tttgtttgtg gtgatttgat aaacgtcata 912900
ttttacaacg gttataaggg aatattggtt tgtcgttttg actgctaaat cgtttgactg 912960
ttttaaatga tttattgctg ttctaatttt cttttctgaa agctttaaat cagacgataa 913020
tcgtgcaatt gatgttataa aactgcctct ggggatcact gtgcctttcc actttttatc 913080
tttccagttt gccattaaaa gacagtggat aaagacatct ttagtattct gatcagtgta 913140
ccattcccat gatgtaaaac tgcgaaacag tttaataaat gtatcattat ccactaatag 913200
aactctttct ataaagcatt aaggaaaaag tagaaaacta cttttccttt ggcttgattt 913260
caatgcaaac tggctgtgtc ggttctgcta catcacctga taaatccagc tgtcctgcaa 913320
ctactcctgt aaactcctga agtctgaatc cagtaacttc gccagtatcc ttatcatact 913380
gaacctgatt aaacaaatga atttcttcac tttttttagg acttaattta gaagtaataa 913440
ccggcttaac actcatttcc tttttatcat ttttaggtat gaaagtaagt ttaactgtta 913500
atgttcgtgc cttatcatca gttccttcgt caaacatatt aaccattact ttttttaatt 913560
cttcatcaat aagcttaaca atagaaccgt tatttatatc taaaatactt cttgtatatt 913620
ttgcttccat tttcatatcc ccctaaaatg ccagtacaac atctttgcca ataagttctt 913680
ttggcagttc cgcagtaaga tactgtttga taagtttttg tacttctttt tcaaagtagc 913740
ctctatctgc aacgaatagt gcaacacggc catgctgatc aactcgaaga ttaaatttac 913800
gttccacctg aataagttca ggataggtag caaccggtgt aagcgtaacg attgggttaa 913860
tagtcacctt gcctgcaccg ccggcaaatg catcactctc aactaccagg ttaacaccaa 913920
tgccattgtc gacctgttta acagtttttg aattgtacag attgcttaca gtggagatta 913980
atttatccgt attgtctgta gggacatagc atgtatttaa gttgatgatc atttcttcag 914040
gtgatatcca ttcatttaaa ataagtctgg gtacaatagg tttacagtga ataagtatct 914100
gacgttcata tgtatcatct acgctactga gtactttgat ctcattacca tccgcttgaa 914160
taatcagcgg cagctgaatg tttaaattct ttgcttcaac atcgatgtat gacttgataa 914220
tttcaacaag tccgcttaat gaacgcgtat cgatactttc aatacctggt gttgtaaccc 914280
ttcttaaact gcctccgaat ttcgtatgaa gcataccttt aatttctgcc tgctctaatt 914340
gagcgttttc tttcgcattt gctaattcaa ctactttttc aattgcttgt ctaatcattt 914400
ttaatttcct cttcttcctt tttatttgtt attcttgggg tataaaattc atcccgttct 914460
tcatgtccca tacggtaacg ccatagcggg cactctacag caggacattc tcttacttcg 914520
tttgattgga aaccgcagca gtcaagacac ttgtatctta ttgccttggc tctgctaact 914580
ctcttcccgg ctgagtcctt aaccattttt tcaaacatgt ttccatccat aacatcactc 914640
ctttggcttt ttcaacactt atagacacat cctttataac aaactgtaca aatgggtaat 914700
cttataactg aatactaaaa cgtttctata cacgtcgcat atgcaccttt ttgttaaaat 914760
actcttacta tcttgccggt ggccttttgg acctctgact tcataaattc ttcatctgca 914820
ttagcatcgc taagatgcaa cagcattatt tccttagttc tgtacagttc gcacgattta 914880
agaaaatcaa tacatgtatt aagattcata tgacttctca taagccgttt aatatgagta 914940
tcaacaaaag gatttctgtt tggattgtta agctgatgtt ccaacctttc actgatataa 915000
ttacattcaa tcataatgta atctaaattc ttaaacgaat aatcgcaata gtatgaatct 915060
gtaataaata ataaattctc atttgtttca tttgaatgga tcaaaaaacc agttggttcc 915120
ttagcatcgt gatgaacttt aaacgccctg atgctgaacg tttttacagt tgtttcggcg 915180
gtgatattag tatctaaagc aaatgtgcct ctttgtccgt atataccgat tccctctaaa 915240
gtaccttttg atgcaaatat cctgatacct cgaagcagca aatccttata acatttggca 915300
tgatcattgt gctcatggct gataagacat ccagccagtt cgctaagttt gtaattcgta 915360
gctttcttga tcatgtccag ctttacaccg cactccacca gcagagtgga aacgccatca 915420
tttattagat aggcgttccc ttttgaaccg ctggcaatac atgttatctt cattagaacg 915480
gatccataga agtttgagca gctttttcac tagcctgtgc ggttgccggc tccggttctt 915540
tttgtggttt tggtgcattc aattccggtg cagcatcatt ttcaacaaag tcaacatcaa 915600
taaattcttt attagcattt gcatttattt ctgactgtac ttcattttta gcaattacca 915660
tttcactgta atcttttaac agttcatcgg gaataacatt aaattttgca agttcctgat 915720
aaagctcatg aacaactgtt ttcaatacca tctttttgaa atccgactgc cataccattg 915780
ccgttttagc tgctttcata gctctatcaa ttctatcttt atcaatgata atcgctgttt 915840
gactgccatt attatgataa gcaactgcat atgcaccttt tactttatct ttattcttaa 915900
aatcaatgtt acgatttaaa atatccggaa tcttgtgatc gatgatctca taatcaccag 915960
ttttaaaatc tcttttctgg acaagctcct caccttcaag aaccacatcc ttaataatgt 916020
ttttaacacc atgatttttc ttacaaaatt tagataaaag tttttcttcg ccctgatatt 916080
gaattttaat attgatatct ttttttccag ctttggtatt atttctaata tccagccaga 916140
tttctttatc attcaaagac agtcccagac gcgcaaatct tttgacctgt ccagggaagt 916200
tacatccaat gaagttgatt tcattgggat taattccttc ctccatcatt tttttatacg 916260
tatttaagat aatatcatta gcaaaagttt tatcacgagg acttaactgt gtacctgatg 916320
aagctgctac tccgtcaact ttagacatca tatacccctt aaaatccgtg ttagctttag 916380
caactgcatt agctgctgcc gtatctttct tttcactcat ttcctattcc tccaccattg 916440
ttaaagtttt ataatcttca tcaacaacca gcctgatcag ctgattatct gtcgctgtaa 916500
tctttgtaac tgattctgca ttatctacaa atattggcat cctgatatta aaatgttctg 916560
ataaagtatc aatgatctca atacctgcat taatgcgact agcattgttg gccatcttat 916620
atggaaccat gcttttttca ttaggaacca tcacgttaca tgattcaata attgcatcat 916680
tggtaatttg tttttcaaac agttcaaaat taactgtctt gaatctctga ttaatctttt 916740
tagtaatccg tttaactttt tcaataatga acttttcaca caaacttaat tcatactcat 916800
aacgatcata atcttcagcc agctgcgcct gtctagcttc aagctcgtca attctcttct 916860
gttgttcttc ggctaactgg aatcggctta tatgagtatt taaagcagca actttaacat 916920
tgcattcatg aatttcttta tcaatttctt caattacttt atctatttca ttatcagtgt 916980
tttcaagatc tgcaagctgc ttcttaataa ctctgtattc ttcagtatct tcaaacggtg 917040
taacagcagt aatcttactt ttttcagttt caatttgact tgacaaatcc attactttaa 917100
tacctaactg ttcattttca tgaataagat tatccagttc aagctcttta gaagcaattt 917160
tgtctttact tacatctgca cccttttttt gaagttcttc aagtttcttt gacttgttaa 917220
tattaaaagt agcaaatatt ttttcctgct gatctgctgg cagtgactgt ccacaggttt 917280
gacaaactct tctattctca tcaaattcca ttgctgatac agttttataa tcattaagca 917340
gttcatttct catttttgac atatagtcaa tatcgttttt gtatctggaa attctaatat 917400
cattgctgct gattgtgtca ttaagtagat ttttcttatt tataaggtta tttatagatt 917460
cctttatcaa tctatttact tcatcaaaac tattaatatg tgcaatacgt gcctcgcgtt 917520
ctttctgctt gatttcagct atacggtttg atttttcaac agctgctgaa ttaccggact 917580
tagctgctaa cttgcggtca ttcagactgc ttatttcttt tcttacttca aatagctgat 917640
tttcataatc cgctttgctc cctgctgttt ctggaatcgc tctttcagct tcatcgattc 917700
gacttggaat ctgttttaat tctttgttaa tactgctcat attggttttt aaaagcttaa 917760
tctgatcatc gatactgcgt ttttgggttg ttgatccgtt taatagcaaa atctcattta 917820
aaggttccag ttctgctact acattaataa tttcttcatc agtataatca ccacaaatat 917880
cagtaagata tttacgtcta tctttccaag acaatacatc actaaaataa gttgggctaa 917940
tgagcatttg tataatttca cgaggaccaa ataactcctc aatctccctg ttgtagtctt 918000
tttccttaac aggaagacca tctacttcat atgaaatggt attgccagta agctccttat 918060
ttttattgcc acgtttttgt gtccattttt ctttgtaagt tttctttaaa actttaacga 918120
ttccattaac atcaaatgta cattcaacag tatgttctag attatgaaga tctccttcga 918180
ctccttttgt tttaggacta taatctgcca tagtaactga cggcttatca gtcaataaat 918240
aataataggc attaatgatc gttgttttac cagtaccgtt atctcctcta atggatttgt 918300
ttgattcatc aaaatttaat tccaggtttc tgattccctg gaagttggtt aatttcattt 918360
gattaatttt aatcgacatt cttatttcct cccttaactg cgttatagca atgtctctta 918420
ccttccttaa aggtgatgat ttttacagta attccccctt ctattacaaa aattttgaca 918480
tccggaacat gtttagatgt ttcgatacga aaacgcacat catgatcctc acgcttcatg 918540
ttaatcattt caaagtaagc atcattaagg tgcttactga acatgttatg gttgaagtta 918600
gttgacatct ttgttatccc ccaacagttc atccataatt tttcttactt cttcagatga 918660
tggaactctt ttatttgcat ttaatttttc tataaattct tttccacatt cttttaatac 918720
atcctcaact ggtttgaaaa tttcaattat atcttctttt gtaagggtgc tgatatcttc 918780
aacatacttg agcatggcaa acctaagact tccgcagatt gaattttcaa taggactgat 918840
tttaaattca tactgtatca gcgttttcgg ctccatattt tcttcaattt catctaatag 918900
tttttttatt gatttgcttt tgttgccgtt aatctttact acttttatat cagctcctga 918960
ttccattgct gattcgatta attccttgat tttatcttcc ataactttct cctctgttat 919020
atctttctat gatctggtcc cgatcagctg ttactgtttc gagactggac cttaaatttc 919080
taattactaa tacctgataa acacttagca caataaacag gactaaaagt atgctaagaa 919140
atttaataaa taccttgtct ttcataagac catacctacg atacctgcta ataattcagc 919200
aaaaatatat aatgctgcta caatggttaa aattccttgc ggttttagat tattgagatt 919260
catggttggc actcctctta aagtcctcag tcatcgcaat agatgctaca gattcaatga 919320
tttcatctaa agtcatgcct gaatcaaata attctttcac taaagcccta atcttatctt 919380
ccactttgac ttcctcctga atatcttcta taatgaagat ggttttattt ttgttaatcg 919440
tcgacgttgc cgcgtcggct tttttgttta cttaaaatct caactaatgt ttgaactaat 919500
tcagttgttg gatttggatt ccatttggtc atatagtcct caaatgctgc tcgaggaatt 919560
acgatagatc tatggccatt ttcattcttt gtacagctcc cgggaaatac cccctgctca 919620
actgcatttc taacaaatgc tggatcctta ttaagacgct tagcacattc ttcaggtgta 919680
atagtctcga ctctttccat ctttctcacc tcctttgatg catcaccttc actcatgcta 919740
taattgattt gtcgaatccc aatatagaaa gtgaggtgaa ataataatga aaaaaattat 919800
tacagctttt tacataaatg attttaatga aaaaatatca gtagaaataa atcaggcaaa 919860
agtttgtcct cattgcgaaa cggcgacgaa taacaacgaa attcaagcat attacataga 919920
gaaaagtgac tttggttacg acaacatgtt tgttatctgt ttctgtcaac gctgcgaatc 919980
ttgctatcta attgaatatc ttgttgataa tcccggttca ggatatcaag ctcatacagt 920040
tgatcaaatc tctgtttatc catatcctca aagtcaagaa tctttttcag acaacatatt 920100
gattctttcg aataaattta tcgacatata taaccaggct ttaaaagccg aaaatatggc 920160
tttaactgaa atttgtggca tgggctatcg caaagcactg gaatttttaa ttaaggatta 920220
tgctattaaa tttaacaata gtgacactga taagataatt aaaatgcaac tatctcaggt 920280
tattgataat tatattgaca atagaagaat aaaatcatta gccaaagctt cttcgtggtt 920340
aggaaacgat gaaactcatt atcaacgtaa acacgaagat tataatcttc aacacttaaa 920400
atcgttcatt cacgcagttg tcgcatttat tgattcagat ttagaagttt acaaagccga 920460
ggaactttta aacaaaccta agaacaatta actttgttct ttttttatct ctttttccaa 920520
ttcgcctata atttccaaaa aatctatata agattttaag aacttattta aaacttttag 920580
ccattcgata tcaatctcct tttttaacgt ctcaataatt tgctttctat ccataacttc 920640
ctcctttttt tcttctgccc ctttcgtgct ataattagct tgaaaggagg taaaatataa 920700
tgactaaatt agtaaaaccc ggtaccgata atgaaccaaa aggaaaatat aaagaagtcg 920760
gtccccgtgg tggtgaagta cctaagccta gagttgtttc aatagatcct ggcgatagat 920820
taccaccaac ccaagaaaaa ggtagaaaat ggaaaaaaat ataatctacc atcccttagc 920880
actctactgc tttgggattt ttatcttcct cttagaaaaa caccatacca gtgaaaaaat 920940
attaacttga atccatgatt caacatataa ttcactgttc tctatatact tcgttatata 921000
atgatgtatc atccctgcca ctcctcctaa tctgttttaa ataatttctt ttaacaccgt 921060
ttttataact tttaatatgt gtcttttcag gacacttatt tttatttaga gttataattt 921120
atttggtcga tgaagtattt tagtctttag taacttttaa agttactaac tgtgcaaaaa 921180
aaataggcat aggatcttgt atttcaagta attcaatcat tttatcaatt tcatcactac 921240
caaaaatacc aatcttcatc ttttcataaa atgttttttc tgtcattccc aatgcaaaag 921300
ctacttgtct ttgagaagta tttctttcag ctataagacc ttttaacttt tgtgtatcaa 921360
tcatatcatc acctcccttt gtaacttatc acgttaccat aataacattc tttttgtgac 921420
ttgtaaagtt attttttgta caactttaaa cgtataagtt actattcagg tgttttttgt 921480
tgcacgttaa gttatttatg ttataatttt attgaaattc aataatagga agtgataaca 921540
aatgacaatt ggtgaaagaa taaaaaattt aagattaaaa aataactata ccttagatga 921600
aattgcagat aaacttggta catctagaca aacaatattt aaatatgaaa ataatatagt 921660
aacaaatata cctagtgata aaattgaaaa gttagcatta attttcaatg tcagtcctgc 921720
ttatataatg gggtgggaaa attcacaatt aggtgactat gaagaaaatg tcgaatattt 921780
aaagaatcaa cctgaattgt tggaactgta taaggaaata cttaaaaatg atcaacttgc 921840
aattttattt gataaagcga aaaaactaga accaaaagac ctagaacaaa tactaaaaat 921900
catcgataca tttaataaag aaacgagatg attatatgga atttgaggac tttctaagat 921960
ggcacaatat tagtttagtg ctggaaagta tgtcctctta tgtgagggga tttgcatatt 922020
ataatggtga gtcatattta gttaccatta atgcacgctg ctgcaaatgt caacagcaaa 922080
caactgctat acatgaactt attcacatct ttgaaaacca ttttacgtgt ccacaagaat 922140
atgccgaaca gtgcgaaaaa gaagttcatg atattattga attattaaaa aagaaatttg 922200
gaattaaata attggagaga ggggtcaact atatgaacaa aattacaaaa gaagaatttg 922260
aaaaattaaa taaatggtat tacagtcctt attttgctat ttttttatca ttttttgggg 922320
ttctttatgg aataccatta ataattgcca ttactttgca attcattaga caaaagaaaa 922380
ttaaactatt actacaacaa taccaacctt taataggtca tgaagaatat gtttttggta 922440
tcattgatta caattctaaa ttagaggaag caaaaaacaa ttactctaaa gaagttcaga 922500
atttggaagc aaaaataacc agtatagaaa aagagtattc tgaaaaagtc caaactttag 922560
aaaaaaacat taaagaaaaa gaatctgatc taaataaaaa tttagcaatc aatgttaaga 922620
atctcaaaat tgatattgaa aacttaaatg aagagaaaca aaatttatta aatgaactag 922680
acactttaaa atcagaagca ataaaaaaac atttcgattt tgctgatttt gaaaatgtca 922740
cttctgaaga atacaaaaat aaattaagta tttctcgtat taatgaagag aatgatttaa 922800
aaaatggcaa cctacttgct atatcacctt acattgagga taaaaagttt atagcaaata 922860
atacaaaaca aataacccgt ttatttaatg cagaatgtga caatgtaatg aataaagtca 922920
ctataaaaaa tatcgatact tcccgaaata aaataactcg ttcattcaat agtttaaata 922980
agatttttga aactgatggt attcaattaa atcaaaactg gttacaaatt aaactagatc 923040
aactaaacac gctatatcta tatgaaatga aaaaaaataa tgaaaaagat atacaaaaag 923100
caattaaaga gcagatggta gaagaagaaa aggtaagaag agaaatagaa aaacaaaagc 923160
aaaaattaga aaaagaccag aagcaattta acaatgaagt tacacgaatg atgaaatatc 923220
tacaaaaaac ttctaatgat gctgaaaaag aactatatat ggataaaata cgtgaattag 923280
aagaaaaaat aaaaaaattg gaagaagaaa aacaagttgt tcttgatagg gaaatgaacg 923340
caagagctgg atttgtatat attatttcta acattggctc atttggagaa aatatttata 923400
aaattggtat gacacgtaga ctagagccta tggacagaat taaagaatta agtagcgctt 923460
ctgttccttt tgaatttgat gttcatgcaa tgatttttag tgataatgcc cctgaactag 923520
aaaatatatt gcaccaaaca ttccgtgaaa gaagtgtaaa taaagtaaat tttagaaaag 923580
aattctttaa ggttacactc gatgaaatag aagatgtggt aaaaagaaat tataataaaa 923640
cagtagattt tattaaagtt cctactgctg cagaatatag gcagacttta gaaattgaaa 923700
ataataatta gcgtaaggtg ataaattgaa tctatacata accaaatacg gtaaatacac 923760
ttcatagtgt ttatataaat aaaatacgaa gggagaataa aattatgaat cataatgaaa 923820
agcaactata tgatgaatta aggagtactg ctgaagaatg taatgagcta atgaatatga 923880
tcttcgaacg ccaattacct tcttgtgaat taaaaagtaa atataaaatt cttaaaaaca 923940
gttgtaaaaa tagattacag caaataaaaa gagttggaaa gccaataaat gtaagtcaaa 924000
ctgtatataa taaattttta agaaattaca gcgaagctat ggcctttggt ttcactgaac 924060
caacaaatgg aaaccttgat aaaatgattc attctttaga agaagcgcgt tacaaattta 924120
caaagttttt aaatgaataa agtaattcta tagggagggg ctaaaatgga tgaaaatgat 924180
tacatatctt taagaattga taatcaaata gactggtacg ataaaaaatc tattaaatat 924240
aaaaaatgcc ataattttat tacaatatgc agcatatttg tttctacatc tggatcaatg 924300
ataactattt taggatatat ttttactgat ttaaagatcg ctttctctat ttttggggct 924360
atggctggat tttcagttgc ctttatgcta tcactagata aattaaaaga ttttcatgaa 924420
cactttctta catatagagc aacttgtgaa aagttaaaac aagaaaaata tttatttcta 924480
acaaaatcta gtgattatta tcaaaatgat caagccttta atttatttgt tgaacgctct 924540
gaaagcatca tggcaacaga aaatcaaaat tgggctcaac taaatgaaaa aaagagggat 924600
taaccttctt ctattataat atcataagtt ttctcaaaaa tttctggttt acagggatac 924660
cgttcaccat tgacaccagt aataatccaa tcaccttttt cagccttcat tctaccttct 924720
aaagtatcta tatagaaaga atgatctgtt tgatatgcat caactagtat tggtttttta 924780
cgcactttat attttgtcat atgaaccacc tctttgttta tattataacc aaattcattt 924840
tagaaaggaa gtgaaattta tgccatcatt aaaaacctat gatcttttta tcagtcatgc 924900
ttggttatac ggcgatgatt atgataattt aattaattta cttgataaag cttcttactt 924960
ttactataga aattattctg ctccaaaaga aaaaccatta gcgatatcaa acaatgcttt 925020
tgattatcaa atcaaagaag cgattgataa aaaaataaaa cctgtaaatt gtgtaattat 925080
attaggcgga atgtacgctc acagaaaatg gatgaaatac gaacttgaag ctgctaaaaa 925140
acttagaaaa ccaattatta tagttgctcc ccgtggacaa gaacgtatgc cgatagaatt 925200
acaacaatat cctgttgtgc gttggaatac agattcaata attactgcga taagacagtt 925260
atcaagataa aaattcataa gtcctaacag gtaaatcata aaaaaactcc actgctacca 925320
acagtgaagt cgaatgaagt actaccaata cttcatattt ataaaagact caaccaaaag 925380
tccttttacg tgcttaatta taacacctaa acacgtctaa ggcaaatata gaaaggacgt 925440
gtttttatta tggctagaaa gcagactttt aagcgcaggc cgaacaaagc aggaacagta 925500
ataaaactat caggtaaacg aagacgcccc tggtgcgcta aaataactac tggaaaagat 925560
attattaccg gtaggcagat acaaacagta ctgggaacct ttgagacctg ggatgaggct 925620
gatgatgctt tgactttata caggcttggt caaaaaaata agattactga tacggaagct 925680
gaagcacttg cacccgatac attccagaag cttgttgatc agcgtgaaaa gaatatgcct 925740
acctttaaag aaatctttga tattatatat caggaagaat tgtgcacatt atcgaaaagt 925800
gctgctcaag gttatagatc gtggattaaa cattttaaca gtatatacca ccacaagatc 925860
agtcaaataa gtctggccga tctgcaggaa atatttgatc gtgataaagc tggttacggt 925920
acaaaagtac atatgaaagt tttagttagc aaaatatttg aatatgcagt tattcacaaa 925980
tatataaatc gtgacgatga ttacactgaa tatataaaat gcggcaaagc aaaagaaagc 926040
actaaacatt atgctttctc aaatgacgaa ataagagtat tgatgagcga taacagcgat 926100
acggctaaaa taatacttat ttatattttc accggtttaa gagcaaatga actgctgaat 926160
atcccgcgta aaaatatttg tttaaacaca gaattcccct atttagtatc tggatcaaaa 926220
actgatacag gtaaaaatcg agtaattccc attcatactt ttatcgaacc ttttgttaaa 926280
cagctgttga tgaagaaaaa gaaaagaata attgactgta cctactatca gttttcatct 926340
atgttctcct cttttttaac taatcataat atgaagcata caatacatga tactagggat 926400
acatttgcaa cattatgtca gtctaacaac gttgatctgt ttataagaaa acgtattctt 926460
ggtcacaaaa tgaaagatat aacctttgat acttatacat ctaccgtaat tgaaacacta 926520
tataaagaaa tcaacaaaat caaggttcct aagtcttgaa tttttgttac ttatttgtta 926580
cttacgaggt acatttaact gcttctaatc gcttgaaacc cttgatttat cgtcaataag 926640
atggatagat attttcaagt cttgaaaaaa caaaacattt atttgaataa acgtgtatgc 926700
tttatgtgta aaataaatat acggaggaaa taagatggaa aagaaacctg taaaaattgt 926760
aacaattggt ggaggtagta gttatactcc tgaattaatg gaaggattta ttaaaagata 926820
tgatgaactt ccaatcaaag aaatttggtt agtagatatt gaagctggta aagaaaaact 926880
agaaatcgtt ggtgctatgg cacaacgtat gtgggacgct tctccttacg atgttaaagt 926940
acatttaact ttagatcgtc gtgaagcttt aaaagatgct gatttcgtta ctactcaatt 927000
cagagttggt ttattaaacg ctcgtattaa agatgaaaga attccattct cttatggtat 927060
gttaggacaa gaaacaaatg gagctggagg aatcttcaag gcatttagaa caattcctgt 927120
aatccttagc attgttgaag acatgaaaga attatgtcca aatgcatggt tagtaaactt 927180
cacaaatcct agtggtatgg ttactgaggc agttatgaaa tatggtaaat gggatcgtgt 927240
aattggttta tgtaacgtac cagttggggc tatgatggct gaaccagaaa caatcggaac 927300
aactttagat aaattaattt ataaatttgc tggattaaac catttccact ggcaccgcgt 927360
ttttgattta gacggtacag atgtaactgg aaaaatcatt gatgcaatgt atgaaggtaa 927420
agattctggt attcctgcaa atattcatga tatcccattc tttaaagaac aattaaaaca 927480
aatgaattta attccttgtg gatatcatag atattactat cgtcaacaag aaatgttagc 927540
tcatgggctt gaagaatata atggaattgg aactcgtgga caacaagtaa aacaaactga 927600
agcagaatta tttgaattat ataaagatcc aaatttaaat tacaaacctg aacaattaac 927660
taaacgtggt ggtactcact attcagatgc tgcatgtgaa actatcgcat caatctatgc 927720
taataaaaat actcaccttg ttgtaactac taaaaacaat ggtgctgtac ctgatcttcc 927780
tgctgattgt gctgtagaag tatctgctca tatcggttca gctggagctt tagctatcgc 927840
ttttggacca ttagaacctg ctcaacgtgg ttggttacaa tgcatgaaaa atatggaatt 927900
atgtgttgaa gaagctgctg taactggtga ttatggatta gctttacaag catttatctt 927960
aaatccacaa attccttctg gtgaaaatgc taaacgtgtt ttagatgaat tattaattgc 928020
tcataaaaaa cacttaccac aatttgctga taagatcgct gaattagaag cagctggtgt 928080
tacagtaaaa gatgaaatcg ctagagattt agactaaata aaaaattcgt gaatttgata 928140
tgatctctct aaaatagaca acttaaataa agttgtccat gaaaagaggg atcttttctt 928200
atggcacgta atatacaata aaaaaagata caagcagttt tagagtataa gaacagaatt 928260
aaagaaataa aacaaataat aattcaagag catttaaata gtaaagattc tttgagagat 928320
ttaagcaata aatacaatac tcattcttct tcatctttat gaagttgggc tatcagttat 928380
aatagtcact aaaaattaac agattatgat cctaaaggag atgtctacat gaccaaatca 928440
aaaaaagcaa cattagaaga aataattaaa attgtataat attatttaga ttatgagaaa 928500
gaatataaat cagcagctga actttttgag gtttcttact cacaagtata tcaatgggta 928560
aagaaatatt tagaattagg tgaagaaggt ctaaaagaca gtagaggtaa gcgcaaagag 928620
gaatcacaat taaatgagtt agaaaaatta caatatgaaa acgaacgttt aaaacaccaa 928680
tctgaactta aagaaaaaaa tattatctta aaaaagttga aggaagctaa tattactcaa 928740
agtatgtcaa gagttggaaa atgtatcgat aacggttctg ctaaaagatt ttggagaatt 928800
attaaaagtg agatgtatta tcttaacaaa tttaattctt tcaatgaatt aaaaaaagca 928860
attgaaactc atattgactt ctacaataac gaaagattta ataataaggt accaatgaaa 928920
gtacgtttag aagctctaaa tggtactgaa aatccagcac aatatcctac caataattca 928980
ttaaattacg caatggtata ataaaagatg ctttaccaaa tggaaaagca tcttttattt 929040
tgttatttct tatttcttgt tggtttgtac atcccacccg gtgaataatt atctgcatat 929100
tttttagata cttttttcac taatgaaact acttttttct ttatagccat gttttttcac 929160
ctccatactt acacctgtaa aaaataaagt aaaaccaatt atcatgctta gtcgtggttc 929220
tataggataa attaatccaa tcacagccag acatccccaa aaaattaatt tacttatttt 929280
cacattccgt gcttcatgat tttcttgcca cataaatgct ttagcagcaa taagtattgc 929340
cataattaga agatagctat tttcaaaatc cgcaaaatag agcgtaccaa gatataacaa 929400
agtcgttaaa aacatacagc gataaaaact atcagcatga taaccgtcta caaatgtccg 929460
taatccaact aatgcaataa taaatattat tgtttctagt accatatttc taaaaatgcc 929520
gattgctaac aacaaaaaaa ataaaatcat ttgagtcaaa atgagttcaa taccaaatct 929580
tacttcatca atttcatcct cagtcacatt atcaacatct aataaaaata tgcttatttt 929640
ttcacaaaaa cgtttcatat ctatcctcca tgtccattat actattaaat cttcctaaaa 929700
atattttcaa tgtactaacc ggtcctattt tgttattaaa tacttctaaa aaaattaaaa 929760
ctttgtgccg gacaatagca caaagcttta aaaaaagaga ttagattatt aattcaaact 929820
tctatccaat agacgtttgt gagaaatagc tataaatatt acttgcggcc atgtagtaat 929880
attataactt ggagattatg tatagaaaga caatactttt tattttatta ttattacatc 929940
tctcccataa tctattatac tacacaactt aacagcttgc ggttttatcc tttttttcta 930000
cactaacggt caatattatg acataaacgg ctttttaatt atcaacattc agtaaaatat 930060
cgcaatgcac cttgttattt tcatagaaat attccattgt tccatgatag gtttctacaa 930120
cctctttaat gattattaat ccttttccat gatctcttcc ttttttactt tcataattaa 930180
gaggtctatt agtcgaattt attatgctga tcaaaagcat attgccttta ctaaaaattt 930240
tgatttcaac tatcttctcc gctgttttta aagcagcttc agtagcatta tctatcagat 930300
taaataatag agaacataat ttgtcttgag caatattaac attgcgatca atcactgcat 930360
ctacaacata attaacttca tcgttattgc gaatcttcgc atttaaacaa gcatctacaa 930420
aaatatttcc cgtacgtatc aatttaactg gagcatttaa atcttcttta attgctttta 930480
aatattggtt agcgactgat tctgtttcga ctacttcttc taggacttgt aaatgattat 930540
taatgtcatg cttaaactta taaagacgtt cttgttcttt ttctaattca ctaatatgac 930600
ggcgagttgt agcatatgaa taatttgcta actctaactc cttattacgt aaatacatac 930660
gggaagaatt gatgatataa ttatttacca aaatcatttg aacacctgct aagatcaata 930720
taaaaaagat ataaatatcc ccctgttcaa ctgataatac gtttaaaatc agtacaataa 930780
tcacttcaac aatattgatc aaacaaaacg aatataaaaa ttttttaggt aactgatgtt 930840
ccacaaaatc acgtttttga accgcatatt tgcatatcaa tgctgatgat atatagtttc 930900
ctaaaggaaa aacaactcgc atactccccc atacgatatc caaatatgta ttgtcaaaaa 930960
tttctagcgc cactgcaatc ataactgagc cgacaataat ttgaattgaa taataaattg 931020
tagtgataaa caaattatta agcctaaatc tcttaaccaa taccccacaa taaataaaat 931080
ccaaactaat acacattaaa ttaccaatta catataacca gccattatgt ggtgaagtat 931140
acgtaacaat attcaaaaca aacgtataac ttaatataac cataatattt ctaagcatgt 931200
tttctttacg aatatatgga taggttaatg aaataacata acttaaagca acaacatata 931260
tcaatgtata taaatactca ataaaaaaat taatcatcac tctttgatct cctgcattaa 931320
aagattaaat acatcttttt ttcttcttct actaatttct agcgattcat caataccttt 931380
taattttaaa atatatccat tcatcgaaac aaccatatta atattgatta tctgactttt 931440
atttatttgg acaaaattat ctggtaaata ctgattaact tcttcaagcg tcatataagg 931500
aatatagaaa ttattatcat tagtataaaa atgtaagtat ctttttactg attcgatata 931560
aataatattt ctacttcgaa aatgaaaaat ctctcccttt ttcttgatcc agatatcatc 931620
attttgttgt ctacgattta tcgctttaag caaggttggc gttaactttg tttctaattc 931680
tgatttaagt aaatatcctg ctacattaat atcaaacgcc tcctgcattt tattttcata 931740
attagttatg tatattatga tcgtattttg tttcaataat ttttttgcta cctgtattcc 931800
actcattgtt ggcatatcga tatctaataa aagaatatca aagtttttac cacaattaaa 931860
aaactcttca acatcttgaa aaagttcaac tgtatatggt tccttaattc tagcctcctc 931920
tacataccct ctgattctaa gtagcattga ccgctcatca tctagtatac ctattttcat 931980
ctttacacct catttattta ttatacttga taaaaccttt tttgactaat taaaaaaggc 932040
ccttaggcct tatcctgttg ctttttttca tagtaatttc ttaccagcac ttgtgtttta 932100
cgaatatgat tttgaatttt ttctttagct aaatccttat cacgagctaa aattgcctca 932160
taaatttctc gatgctcctg tgctgctgaa attaaacgat ccggttgacg aattgaatgc 932220
cttgaagtta catgaatata ataattaata tctgttaata attgctcaaa atactttgat 932280
tgggtacaac gataaatagc ctcatgaaaa gcaatattaa tttcattaaa cttctcttga 932340
tcaccttttt cagcataaaa ttccattaaa tcatacactt cttttatctt ttcaagttcc 932400
tcatcattaa ttcgctcaat tgctaattgg attgctagcc cttctaaagc ataacgaatt 932460
tccaacatat catcgatatc acgatgagaa aaccctagta cataaactcc tttattagga 932520
atacttttaa ccaaaccttc taattccaac tgttttagag cctcacgaat tggagttcta 932580
gaaatattca actctttaga caaagcaact tcatttaatt tttgtccttg agtatattcc 932640
tcatttaaga ttttatcacg caaaacggtg aaaattttat ttccaagcga cccatgtccg 932700
gtattttcta ataaattctt tgtcattgtt taacctaact ttctgatgat ggctgcggtg 932760
aactcgtctg ttgaagcact acccccaata tcaggtgtta caatagttcc ttcttcaact 932820
acagctgcta aagcctcacg caatttatta gcatcatcta atttccctaa tgcctctaac 932880
attaatgcaa atgctaataa taatgcactc ggattagcga tacccttacc agcaatatct 932940
ggtgcacttc catgaacagc ttcataaatt ctaaattcat caccaatatt cccacttggt 933000
gcaaatccta gaccgccaac taatccagca cataaatcag aaacaatatc accatataaa 933060
tttggtgcaa ctaaaacatc aaaagtttct ggacgaatta ctaattgcat acacatgtta 933120
tcaacaataa cctcttgtgg ctcaatatct ggataatctt tagccacatc tctaaacgct 933180
tctaaaaata atccatctgt atatttcata atattcgctt tatgaactgc tgttactttt 933240
ttacgtctat tgttcttagc atattcaaaa gcataacgac aaatcttttc actcgcttca 933300
cgagtaatta atttaattcc atttgccata tttggattga tcatatactc aatcccttta 933360
tataaatctt cggtattttc acgaatcata accagatcaa tgtcttcata acgagaattg 933420
attcctttaa atgatttgat tggacgaaca ttagcataag ttgcaaactg ttgtcgcaag 933480
gcaacattga cacttctaaa tcccgttcca atcggcgttg ctgtcggacc ttttaaagcc 933540
catttatatt ctttaatagc atcaacaagt cctggttcaa aaacttcttt cgttgtagct 933600
gcatattcag caccagcctg atattccacc cattcaatgt caagcttcat cgctttagtg 933660
atatcaacga cactctttga tatttctttt ccaattccat caccagggat taaaacagct 933720
ttcattaaaa ttcacctccc aattctttaa ttgcatttaa taaaccaccg taattaatca 933780
ttactttttc acgaggtgat aatgttaatt cagcctcgat tgaatcatta gtagtttcat 933840
taattacttt tactttacca ttatgttcaa caacatcttt gatattaacg attttataac 933900
tatcttggtc attgaagaaa tcttggtctt tagcttcaat aactaaaggt aaaataccat 933960
tattaattaa attggaacga tgaattctcg caaatgatac tgcaaagatt gctttaatct 934020
ttaaatagtt tggtactaaa gccgcatgtt cacgggaact tccttgacca taattatcac 934080
caccaacgat gaatccccca ttattagcaa ttgcacgatc atagaattca ggatctactt 934140
tactgaatga aaattttgct aaatgtggca catttgaacg atatggcaat aatttgctat 934200
ctgaaggaac aatatgatct gtcgaaatat tatcaccaac ttttaaaaca acttttccac 934260
taatttcatc tgtaattttt tctccacgtg gaaccggttt aatattaggt cccatatata 934320
cttcattatt ttcgtcatat tcatcaatga agaaatttcc atttttaata aatggggtat 934380
ttggcacctc ttctaaatac atatcatctt caaattcttc tgacatgtac cctttaattg 934440
cgctcaatgc cgcaatttcc ggtgatacta agtatacgct tgcatcattt gttcctgaac 934500
gtcccttgaa attacgatta atcgttctta atgaaatccc ttttgagagc ggtgcttgac 934560
ccattccaat acatggtcca caaccacatt caagaatcct tgctccagct tgaaccatat 934620
cagctaatgc tccattttgt gaaagcatcg caagaattga acttgatcct ggcgcaataa 934680
ctaaagaaac atgatccgca actttgcgtc cttttaaaat cttagctgcc ttcatcatgt 934740
cagcaaaaga tgagttagta caacttccta tcacaacttg atttactttc attccttcaa 934800
gttcttttac tggtactacc gcatctggac tatgaggctt agcagtcatt ggcactaatg 934860
cacttaaatc aacatctaat tcttgatcat atgtagcatc ttcatcagct ttcatttcaa 934920
tgtaatcatc tactcgccct tgttgtgcta aatattcttt tgttctttca tcggtcggga 934980
aaactgatgt agtggctccc aattcagccc ccatattaca aatcgtagca cgatcagtca 935040
atgataatga agcaactcca tctcccgtat attcaataat cttattaacg ccacccttaa 935100
ccgttaattg ctgaagaata tataaaataa tgtcttttgc acttacccat ggtgcttttt 935160
ttccagtcaa attaacttta acaacactag gacattgtaa gtaatattta cctgttgcca 935220
tcgctactgc gacatctaat ccccctgccc caatagcaat catacccatt gctccacaag 935280
ttggtgtatg tgaatctgat ccaactagag tctttcctgg ttttgagaag ttttctaatt 935340
gtaattgatg acaaactcca ttacctggtt ttgaaaaaac aatcccatgc tttttagcca 935400
cactgcggat aaattcatga tcatccatat tttcaaatcc tgtttgtaac atgttgtgat 935460
caatatatgc cactgctttc tctactgcaa catgtttaat attcattgct tctagttgaa 935520
gataagccat tgtacctgtt gaatcttgtg ttagtgtttg atcaatttga attccaattt 935580
gttctcctgg aacaagattt ccatctttaa gtttactact taaaattttg tatgctaaat 935640
tcatacccat cacgatatac ccccattatt cttatattgc atacaattat acaaaaaaac 935700
aatcttgatt acaacccttt ggaacaaatt ttaccacaag atgtactaaa aataaaacac 935760
tttaataaaa atctattatt tacttgattt aatcgagtaa tttttaatta cactttttta 935820
ataataaatt tgtgaattcc taaaataaaa tatctacttt tcttcttaaa acaaaagcct 935880
tactataaat atcaatgaaa atatgttaga atacattggg tgataaaata tgttaataga 935940
atgttcaaat ataacaaaat catttcaagg gattccctta ttaaaagata taacctttaa 936000
aattgatgat catgataaag tcgcaattat cggagttaat ggtgctggta aaactactat 936060
tctaaaaatt attgcgggcg aagaaaacta tgatagcggt gacctttttt gtaataaaga 936120
attaacacta ggttatttaa aacaacagca tgacttagcg atggataaaa cagtttacga 936180
tgttggcctt gatgtttttg caccattgat cacaattgaa aatagactac gtcaattaga 936240
gaatgaaatg acaactgatc atagtgaacg tattttaaat gaatatgatc gtctaactca 936300
atcatttcat gataaagatg gatatagtta tcccagtaaa ttaaccggcg ttttaaaggg 936360
actgggcttt agcgaagaag aattcaattt aaaagtttca atgctatctg gtggtcaaaa 936420
aacacgttta gctcttgcta aaatgctgct tcaagaacca aagctattgt tacttgacga 936480
acctactaac catttagata atagtgctat taatttctta gaaggatatt taaaaaatta 936540
tcctcatgca atcatcacag tcagccatga tcgttacttt attgatcaag tttctaataa 936600
aattgtagaa gtcgaaaatg gaaaatccaa aagctataaa tgtaaatata acgaatattc 936660
aattttaaag aaaaagcaaa gagctgttga tttaaaacat tatttaaatc aacaaaaaga 936720
aattaaaaga attcaagaga gtatcgatac actaaaatca tataaccgtg aaaaacaagt 936780
taaacgagcc gaatctaaag aaaagcagtt agctaaaatt gaacgtattg acaagcctga 936840
gaacttgcca gatacaatca cgattaattt taaaccaaaa cgtgagtccg gttttgatgt 936900
tttaaaaata gagaacctag ctgttaaatt tgatgaaatt ttatttaaaa acattgatat 936960
cgatataaaa aaacaagagc gtattgctct tgtcggggat aacggtgtgg gtaaaacaac 937020
tctttttaaa actatcctcg atcagctaaa tgcttatcaa ggtaaaatta aatttggtag 937080
taaagtagac cttgcttact atgatcaaga acatagcaca ctagcaatgg ataaaactat 937140
ttttaatgaa attagtgata attttcctaa gatgactaat actgagattc gcaacagtct 937200
tgccttattt aacttcaaag gcgatgatgt ttttaaagaa atctctttac tttctggtgg 937260
tgaaaaagga cgtgttgtac ttactgaaat attattaaaa caagcaaatc ttttaatttt 937320
agacgaacca accaaccact tagacattgc ttctaaagaa gttcttgaag atgccttaaa 937380
ccaatttgaa ggaacaatct tctttattag ccatgaccgc tatttcatta ataaagtagc 937440
aactcgtgtg atcgaattaa cgagcacaaa agccatcagt tacgatggta attacgatac 937500
ttatttaaat cataaaagcg ttgctaagcc gctcaaaaaa gaaaatgttg attatcttga 937560
tatgaaacag caaaatgctc tttatcgtaa acagcaaaat aaaataaaaa agatagaaac 937620
taatatttct atactagaaa ccaagatcaa cactttaact gaacagcttc atagtgaaga 937680
agttctaaat gattatcaga aatataatca gatcaatgat gaaatttccg aattagaaaa 937740
tcagttaaat actttaatgg aagaatggga agccctgcaa taagggcttt ttatattctt 937800
ttaactccaa gaatacaata attttcatct acacctgagc cttcacaatc aacatactca 937860
acttttacta cacaactgat atttgttttt cctagttttc gtaaagaaac acaatccccc 937920
tgctcaattc cctcttcttt acaaacaact aaatggttaa tcacaccgtt acagatttta 937980
tcaaaatatt ggctgtcaac ctgtaaacta cacatactaa aactcctttc aaatctttaa 938040
atattgttta tagtgatcag atccatcaat ttcttcaatt cgtatctcaa tcgttttttc 938100
taaatcctct acaattgttt tttcattaac cagatttttt tgactaatcc aagactgata 938160
tagtggataa attataaatc ttaatgttaa agcaattgat aacaatccga aatctattga 938220
tacacctaat attaatggtt taagtaacat tcaaccatac ctcctagtat tgccattcac 938280
tcatgctttg atactatcta aatcacaata actaacacat atatatgctc taaataattt 938340
attatgtcag ttaaataaaa cattactact atacttaacc atatattgca ttactttttt 938400
gtctaatcta gtggaaataa aaatacttta attcttcaat ccaaatattt aaataaaaaa 938460
agagcaaaat aattaaatat cctgctcttt tctattaacc gtttagtaat tttatttaat 938520
cgatttcttt accagatcca gctctttgct aatttccaat aattccttaa ttgcaatttc 938580
tagattttgt cttgggtgct cttctaagga cttcttagtc gtactaattc tctcggctat 938640
gttttctaaa ctttccatgt taattctccc tttttcttta ttctaccatt ttactatact 938700
ctatcatgcc atatttttgc agaccatatc agactatgat aaattaaaaa aatgtccaat 938760
ttaagctaca ttaatttaaa ttaataataa taactttctt gctctccatg ataatatact 938820
tttgataaag aaatatacaa aaatctctta cgattacaat tataacaaat tcatcacatt 938880
agtccaagat aaaaaaattt ttctctagtt tataaaataa agcaattatt agaataaaat 938940
gcatattttt catttttaaa ggttatattt agccaatatg tattaccctt acacttagta 939000
aatctttgat tttaccatcc ctctttagtg cttttttcat attttggaaa acggttccat 939060
ttacattact ttaaggtata ataaagccgt aaaaacaagg aggaaataaa atgttacaca 939120
aaaaactaaa accattccca agtgattttt tatggggagc ttcaacatct gcttatcaag 939180
tagaaggagc taacttaatc gatggaaaag gaccatcttg tcaggatgtc aaaaaagtac 939240
ctgaaggaac ttcagaactt gatgtgtgtg ctgatcaata tcatcgttat aaagaagata 939300
ttgcattgat ggcagaaatg ggattcaaga cttatcgttt ctctatcgct tggacaagaa 939360
ttttacctaa tggaactggt gaagtcaatc caaaaggaat tgaatattat aataatgtta 939420
ttaatgaatg tttaaaatac ggtattgaac cattggtaac aatgttccat tttgatatgc 939480
cggctgcttt agatgaaaga ggaagctggg gtaatccaga atcggttgac tggtttgtaa 939540
actttgcaaa agttatgtat gaaaattatg gtgatcgtgt taaatattgg ctaacgatca 939600
acgaacaaaa tatgctgact ttagttggac cggtaattgg tacattacac ttgccggaag 939660
gatgcacaaa cgaaatcaaa gaaatctatc agcaaaacca tcatatgctg gtagcacaag 939720
ctaaagcaat ggcattatgc cacgaaatga ttcctggagc aaaaatcgga cctgcaccaa 939780
atatttcatt agtttatcct gcttcttgta aacctgaaga tgttctagca gcacaaaact 939840
ataatgctat aagaaactgg ttatatttgg atatggcggt ttacggtgta tataataatt 939900
tagtttgggc ttacttagaa gaacatgatg cctgcccaac atttgcacct ggagatgctg 939960
aagcattgaa aaatggacat cctgatttta ttggtttcaa ctattacaat actgctactt 940020
gtgaagctag tgatggaact gaaacaatgg atcctggagc tgatcagcaa actgctcgtg 940080
gtgaagccgg attctatcgt ggatttaaaa atcctaattt accaactact gaatttggat 940140
gggaaattga tccaatggga ttccgggcaa caatccgtga aatgtactca cgttatcgtc 940200
tgccaatgat cgttactgaa aatggactag gagcatatga taaattaaca gaagacggta 940260
aagtacatga tcaatatcga attgaatatt taagaaaaca tcttgaacag gtacaattag 940320
caatcacaga cggttgtgaa atgatgggat actgtccatg gtcagcagta gacttgattt 940380
caacacatga aggtatggtc aaacgttatg gatttattta tgtagaccgt gaagaatttg 940440
atttaaaaac tttagatcgt tatcgtaaag attcattcta ttggtacaaa aaagttattg 940500
ccactaatgg tgatgattta tcagattaat ttaatcttaa aaagtcttct atagaaatct 940560
atagaaggct tttttgctaa taaatatagt attataacaa catgttttct atttaattta 940620
agtaaatttg ctaatctaca atcttttcaa ataccgggtc ataactaact aattaattat 940680
tgtttcacct tcttgttgca attattttaa cgcttcaatc acaatttatc tattattctg 940740
atcaactgcc taagcctgct cacccaccaa gatttcttcc tctgaacatt taatatcctt 940800
atatccttgt agtgtttgtt tatataaagc catttttatt tttccttctc atttcctttt 940860
tcatattcta aagctaattt taaatcatat tccattattt tattttctat taaggcaaaa 940920
ctttgaaaaa gcaactaatc atttccactt ttctagcgaa tagcttaatt tttttatcaa 940980
ataaaataat attcccactt gttaatgaat tcaatcattc ctttaaaata ggattcggat 941040
agatatattt aatgctgata atacagcaat aaaaaaacaa tccctcttta tctatatctg 941100
aataatgaga taaaaagcaa gaaaaataac ttttatttaa tgaagacatc atgtttttaa 941160
tactaaaatt attattccta tataataata aaagaatcgg ctgtaaccaa ttcttttatt 941220
ctacatcttc ttcatattta ataatttcac cagtatctgc attaatttct aattcatatt 941280
ccttattacc atttttaatc tctatctcat attttttaat tccatcatcg tcatcataat 941340
ctaactctgt ttttattaag taaccaccac caacacgatc aaaagcgatt ttttgagctt 941400
cctctaaaga aacagccgta ttaacaggag taatcggagt aactgttcca tcaactggat 941460
tagttgtcgt acctatataa tcatcatctt tttcccgttt taataccttt ccactatttg 941520
cgtctacttc tatttcatac ttttctgtat cagttataat agtaaaatca tagtaagtta 941580
ccccatcatc tttatcttct ttagccttaa ggatttttcc ttctacttct tttaaagcaa 941640
tttcttgagc ttcttccaat gttagggcac taactttttc agtacatcca actaaagcta 941700
ttgtaattaa tacaaataaa attattttct tcataaatat tatctccttt caaaatcaat 941760
tgtaaaaatt gtatattgat caactatact ttcaaccgta attgcatagt cataatagct 941820
gcaaattctt ttagcaattg ctaaacctag tccaaaattg ttattatttt gagcccgtga 941880
ctcatcagcc cgataaaagc gattaaatat atagtctaat ttatctgctt ctatcccaat 941940
cccgtgatct ttaaccatta atttttggtc aacatataat aattcaattt tcttttcttc 942000
ttctcttgaa tatttaattg cattatcaat taaaataatt aaaagttgtt ttaaatgttc 942060
tatgcgcatc catatctttg aagttacagt tattttaata ataaattcaa attctgggtg 942120
aacttcttta aaatttgtaa ttacttcatc aactactaaa ttaagatcag ttggttcttc 942180
acaatgaata tccatctctc gggttaaatg aagaagttca ttacacaatt ggattaatcg 942240
ctcaacttca ttactagtga cattaagtga attgctaaga atagcaggat catcttttcc 942300
ccaccgctcc aacatatcta aatttccttt tataattgcc aatggcgttt ttaattcatg 942360
tgatgcatca cttacaaatt gattttgttg taataatgat ctttccactt gatcgattgt 942420
ttcattaaat tccttgccta ataaagctaa ttcatcattt ccctcaataa caagccggtg 942480
acttaagccc tcatttttaa tttgtttaat actctttgta aattgatcaa cagtttgtaa 942540
aaaacgttta ctaatcatga aaccacaggc aatactggta atcaatgcaa caataattaa 942600
aatcaaaaag attacagcaa caatactagc tatgggggtt atcaaatctt catccattgc 942660
atagattcgt ccaataatca ataaataata acccatataa agtaataaaa tcaagctaaa 942720
tactacgatc actgtcataa taataattga agtagtacta actaattgat gtcgtagtga 942780
tttaattttc atgataaacg gtatcctact ccacgtactg tttcaatttt aattccggga 942840
attttattac gtaaataacg gatatatact tcaacgacat ttgttgatac atcttcatca 942900
taaccccaaa cctgatctaa aatcttattg cgactaacaa catcaccgcc attttgaact 942960
aataatgata ataaatcaaa ctcagtcgtt gttaaattta cttcattatc tttgaaaaag 943020
accttgtgct tacttggatc aattttaact tctccataac tatattcaag aagtgctttt 943080
tgaaagttca ttcttctcaa tagtgcattt atcctcgcta ataattcttc cattgcaaac 943140
ggctttgcta aataatcatc tgctccaact tgtaaaccat tgaccttatc catcacctca 943200
tcacgagctg taagcataat tactggcgtt tgtttaatct ctcgcaagcg tcgacatact 943260
tcgattccat taattcgcgg taacattaaa tctaataaga ttaattcata ttcttgctct 943320
aaagcttttt ttaacccaac ttcaccatca taagcttgat cacaacaata acctgcatgg 943380
gttaattcta gctttaatag atctgacata tttttttcat cttcaattat cagtattgcc 943440
atcttcatca ctccttatat tcaaatccaa ttatctttcc actttttgca ctaatattta 943500
tctcaatcag ttcttgctgc tgattctcta tttcaagatg gtaaaatatt tgcatatgct 943560
catattcaat ttgtgaagat acgatagttc ctggaaattg tttcaatgct acaacatgtg 943620
cttcactttt agaataatta atgttattta aagttgtatg taatatatag acaccaaaac 943680
aaataacact aatgacgatt attattatag ttgttataat ttgtttttta taaataatca 943740
gcttttccat tcccatcttc ctttcatcta tatcataacc tattttgccc gattgttgct 943800
taaagaacaa taataattaa ataagaattt tctcattttc taaaaataaa taagtgtgat 943860
ctaaaatcac acttactcaa acaaagcaaa ttctaaataa taaactagat catgaaacat 943920
tctagtatta aagccataac agctgcaatc atctatttct ccatcccaat cattatttaa 943980
tcgttctaat aacagcggta cctctgtaac atctaaatta actgttacaa aaaactcact 944040
acaatctttt tttccagcat actcacgact cggtgaaatt gaaaaattag gatttatttg 944100
taacaacaaa tctttaatca tttgataatc ttttatatct tcactttcaa taattacata 944160
taatctcgct aacatataac cacctctttc ctgcctattt tatcataaaa tattgtttag 944220
ataaaagtat gctattaatt aattttattc tgattatatt tactaataaa tatgttaaga 944280
taaagtaaag agatatattt gaaagctggg ataattatgg atgaatcact aattacgatc 944340
attgggttta ttattggagg cctatctatc tttatttatg gaatcaatct tatgagcgat 944400
ggcctcaaaa gtattgcagg atatcatatc cgtgagtata ttgaaaaata tacaagtaat 944460
ctttttacct caattttagt gggtacttta atttctgcaa tcctccattc tagttctgct 944520
gttacagtta tttcaatcag tctggttcgg gccggattaa tgaagttgga acaggctata 944580
ggaatcacga ttggagcgaa tattgggact tgtgtgactt caataatgat aggcttgaat 944640
gtggaacaat ttgcttacta tcttgtcttt attggggttg taatcatgtt tttagctaaa 944700
aaaaagacga ttggatacat cggcaaagtt gttctgggct ttggactaat ttttgttggt 944760
ctacaaataa tgagtgatca aatgatagcc tttgctaaag aaccttggtt tacaagtatc 944820
atgacaacgt taggaaaaaa accatggtgg gcacttctag gtggaactat agcaacaggc 944880
atcatgcaat catctactgc tgttatcggt gtagtccaaa aactttttac aactggttca 944940
atcactcctg ctgctggtgc tgcatttatt tttggggcca acattggtac ttgtattact 945000
gcggttattg ccgctttagg cggatctatt tcaactaaac gagctgcctg gtttcatgtt 945060
gtttataatc tagcaggtgc aataatagga atgctcgttt taaaaccatt cgttaattta 945120
actaattggg tcaatttgct gctaaacggc agtcaagaaa tgtatattgc tcaagtacac 945180
ttcattttta atatagcttc aactatttta gttattcctt ttgttcgcta ttgtgttatt 945240
ttattagaaa agttaattcc tgggaatgat catcatgata cgctcattga aaatatcgat 945300
gagctagatg atactttaat tgacaaactt cctgtcggag cattagcagt tgctaaaaag 945360
aatacactcc gaatgggacg aaatgttata gccaatatta aattatctta tacttattta 945420
atctctaaaa atagtgaaga ttatgatgaa attatcgaaa ttgaagcact aatagataaa 945480
tatgattctc gtttatccaa atacttgtta aaaattgctc aacagcccac attagcaaaa 945540
aagcaaacta atgaatactt taaaaattat caaattatca aaaatcttga acgaattggt 945600
gacattgtta gtaatttagc taattattac aaacttgttt acgatgaaaa aggtaaattt 945660
tctaacgaag caatcgatga tttaaataaa atgtataaat tagctttaga aatggtccaa 945720
gatgctctag atatttatga acacgataat gcaaataaac ttctttcttc tttaaacaaa 945780
aaagaacata ctttaaatgc tttagaaatt gagtgtcgtc aaaatcatct agtccgaatg 945840
cgtgacggta tttgtgaaga taatatcgct gcttctatca tcattgatat tatttctagt 945900
attgaacgaa ttggtgatat tgctttaaat actgcaaatt caacaattac ggtatacaaa 945960
gatcataaag ttaaatattt aaatgtttga tttttacata aaaaattact ggaataacat 946020
ccagtaattt taatttattg catctttatc ggtttcaccg gttctaattc gcaaagcact 946080
ttttagatca taactaatta ttttgccatc tccaggattc cccgtaaatg ctgcggtttg 946140
aattgccttg attgtcttct tttcccaaac ttcatcactt actataattt caaatttaat 946200
ttttggtaac atatttattt ctacttcatt acctctaatt acttcacgat agcctttttg 946260
aattccacac cccataactt gataaactgt aatcccatga acttcaattt tagctaaagc 946320
ttctttaaca tcctcaaact tatcttcacg aacaaatgct tctattttaa tcacaaatca 946380
ctcctcctta ctctaatcca ttaaatgatg ggtatgctgt ctcattatgt tcagacatat 946440
ctaaccccat ctgttcatca cgtttatcaa ctcgtaatgg tgtaaatagc cgtacaactc 946500
ctatacaaat taaagtacct atcacagcaa ctactattgt tagtaaaatg ctaataattt 946560
gtgcaattaa taagtttgta tctccgaaga ataacccatt ccatctagct acatcattga 946620
ttgaagtttg agcaaaaagc cccgttgcaa taccacccca gataccacct attccatgac 946680
atccaaatgc atctagagca tcatcatatc caaaatattg ttttgcttta gaaatcataa 946740
aatagcaaat tggactacca acaaaaccaa taataactgc agaccaaatc ggaacaaatc 946800
ctgcaccagg agtaattgct acaagcccga caactaggcc ggttacactt cccactaaag 946860
ttggtttatt aattttccaa acatccatca acatccatga taacattcct gaagcagcag 946920
caacagcagt tgtcataaaa gcgtgtattg ctaatccgtc agcttttaaa gaacttccgg 946980
cattaaaacc aaaccaccca aataatagaa ggcttgcacc tagtacaaca aacggaatat 947040
tatgaatacg atatttcgca tgatcataat ccttacgttt acccaagata atacacaata 947100
ctagcgcgct tactccagaa ctaatatgaa caacatttcc accagcaaaa tctactgaac 947160
caatttcagc caagaatccc cctaatcccc agaccatgtg agccatagga taatagacga 947220
ttgttgacca gacaattata aaaataaaca acgctttaaa cttcattctt cccgctacag 947280
cgccagtaat taaagctggt gtaataattg caaacatcat ttgaaatgct gcaaagccta 947340
aatccggaat cgtactggca taattacctg gcgtcgttcc tacattactc aagcccaaaa 947400
agcttagatc cccaattatt cctagatgat catttccaaa cgccaaggaa tatccaaata 947460
atatccacat aaccattgct attccaatta caaaaattga agtcatcatc gtattaacca 947520
cattttttct tctaaccatt ccgccataga aaaaagctaa tcctggtgtc atcaataaca 947580
ccaatgctgt acagattatc ataaatcctg tatctccaga atcaatcata tttcttcccc 947640
ctttatttat gattatattg gaagtataga tgatattttt ttattaagca agatattttt 947700
tatcactaat tattttcagt ttaccttgtc gtaaaaaaac attgatatta tcatagtttt 947760
ttaatttgtt aaaatattgt tatttttata tatgataaaa atagttattg gcatataagt 947820
ttccaattaa ctcgttattg tatattagtg cagttattat taattcattt aagttaaaaa 947880
actatagatc attacaagat aaaattaaat aattgtcatt tttaaactgt ttttccataa 947940
ccaacataga atgattcaca aaattatttt taaagtattc ttttgaaatt aaaatcactc 948000
ctataaaagt tatacctgtg actattaatc atatatataa atcatttggc acagctctaa 948060
ttagaactgc tccaattaca aagtaaaaca atatatatat aattagtatc ttagataaaa 948120
tacttaatcc ttttatcttt ctatttaaaa taaactatat aaaaatcata gcatatctat 948180
tttataaaaa aggcataatt ttttcacaaa actaaaaaga gctgtaacat tctaaaatag 948240
taaaaaaact actcactagt tacggctact tctataagta tatctccttc tttacttggc 948300
tctatagcta tcaatctatt aacttttttg cacaagtggg acatgcaaca taaaagtaag 948360
tacatccgtt ttcacattta taatctatta ttttaaaact actaacttca gtatcaatgc 948420
tctctttagt tactatcttt ttcattattt tcccgtcaaa agagatataa aacaaaaact 948480
atatcacttt tttatgcctt acgttaatat taatcaaaaa ataattatac gatattttgt 948540
tctattacat taataatatt gtatctattt tttatcgtag caagataaat tttgtagtat 948600
attcttgttt tcgtaatttt cctaaaataa tatatttgct aattattcaa gaacttttct 948660
atatcttcat aattagatat ttctatatta aaaacatatg aaaaaaattt ttgcaattca 948720
catatatcat attctttaaa atttatttta tgtatctttt gatacacttc ttttactaaa 948780
aatcttaaat ctgaaatata attacaacat actaaatcaa caacatcttt aaaaatatct 948840
ctatgcataa taacctatcc cctcaagctt tattcacaaa cattttaaat ataaatactg 948900
aattaaaaaa tacatcaatc aaataaacca aaataactct ccaaaatttc aatacaatat 948960
acaagtaaat acctttttaa tatcatatta aatttttaat aatatttttt cccaaaaata 949020
tatcctatat caataaaatt tgggaacaat ttaatcacat aattatcata ttatatagtt 949080
gtaaaaacta taaatagctt aagttctgtt gtaggtggtg aattatgctt gactattttt 949140
tagaaaacac tacaaaaaag aaattatatc ttttttccat cttatattta aagagagtca 949200
cttctgtaaa agaatgtaag tatatactta catttagcag taccagtata atttcaataa 949260
ttaacgagtt gaattttgat ttcaatggaa ttgcagaaat aaatataaca aattcattgg 949320
aacttaaatt aattgtatac gaagatatta cattttctga tttactccat gctatatacc 949380
aaagctctaa tgtattgcat tgtatcaagt ttatgataac caatgaatca aaccattctt 949440
ttttgatatt tgcggaagat aactatcttg caaaatccag tgcatatcga atacgacaaa 949500
aatgtattaa atatatccgc agtatcggtt tggatattaa aaaaaataaa gttatagggg 949560
aagaatacag aattcgattt ttgattgctc ttttatacta caaatgcggt atagattgtt 949620
gcgatattga tgaatattca ataaaactta ttaaagaatt tattatatct actaaccagt 949680
caattacttt tgaatttctt aataacgcta caaatgaata tgattatttt gaatgtctaa 949740
tgtcactttt gtggaaaaga aaagaccaca atgacaattt atctatacca aaggagcttg 949800
aaaaatttaa agagattttt atatacaatg atttgaaaaa atatttacat aatgtaattg 949860
ggaatcagct taacatagat ttttcaaaaa aagactatga ttatatgtat ttagtttatt 949920
tttgtactaa taacttcctt tttgccaacc agtggacaga ggaacgtaaa gagcacattt 949980
ataaaatatt tctttccaat caaaaatttt atgatttata tattcgtctt agtcataaat 950040
atggtaaatt tctagaacaa tctcacattt tcaaaacaat tttaatctat ttttttaagg 950100
atcatctttt tcaattacaa tgcctaattc caaatcagcg tctatatata gatactacac 950160
ctactacaac ttacatcacc aataatgacg tatcaggtat cataaattca tggaaaaagg 950220
caaataatat attatatcca acagataaaa gaagtatatt ctatttaaca acacaaattg 950280
aatttatatt aagacaactt gttccacctg taacaatcat attgttatct gatttaatgt 950340
ccgagataga aatgataaat ctttttcttg aaaaaaattt ttcccgcaat cgaattaata 950400
taactccgtt acttttaaac agttataatt tagaatatct gaacgctgaa aaaaatagaa 950460
taataatcat tactcgagga attgaatatt tattaaaatc atacaatttc tttcaaaata 950520
atactatagt aataatagat tctagaacaa ccttatacga gaaagaaaaa atttcgaatg 950580
ctattgccaa ttatgaagaa aaacaatttc taaaaatttg tgctggaaca agtcttactg 950640
atacagaata ttaatgatca acataagtgc aacagtctat ttatacaaat attatattat 950700
ttaaatagca tattttatct taaacttatt tcttggcaaa aacacttaaa tcaaaaaagg 950760
actgtaacga ataaaaattt taatctttga catcccccct tctaagtgac aattttttat 950820
tatttcactt gtctacctag aaggaagcat atcatttaat ccgttacagc ccctttaatc 950880
atatactaat tcatcttgat ttataacctc ttcatcagta aaatatgctt gagtttgtac 950940
tatgacctct tttcttaatc caattaaacc aattaaatta gggatagcca tacaaccatt 951000
aacaatatct gcgagaataa aaataaattc taatgacata aaaggaccaa ttgcaataaa 951060
gacaatataa ataaatttat aatatggaat cgcttttaaa ccttttaaat aatacataca 951120
tctctcacca taataattcc aaccaattat agtagtaaat gcaaagaaaa ttaatccaat 951180
attaacaata tacttcccaa tcataggaat aaataaacca ttactaaatg cttgtgtagt 951240
cattgcggca ccttctaaac cactagtatg gctattagta agtaaaattg caattcctgt 951300
catggtacaa ataacaactg tatcaataaa cgttccagtc attgatacca atccttgttc 951360
tacacatgaa tcagtttttg ctgcagcagc ggcaattggt gcacttccaa gaccactttc 951420
atttgaaaaa attcctctac taattccttt ttgcattgcc attgtcatag taatacctat 951480
accaccacca agagctgctt gaggattaaa tgcactatga accactaata caactgtctg 951540
cgggattaag ttaaaatgag taattaaaat aatcacaaca ccaccgatgt aaagaataca 951600
catcatagga attacttttt ctgctacatt cgcaattctt ttaatcccgc caattgtaat 951660
aaaacctaca gtgatcgtta ataaaaccgc tgtaacaatt ggtggaacat taaacgataa 951720
ctccattgca tcagaaattg atttaacttg agtaaatgtt ccaattccca ataacgccac 951780
agcaactcca aaaaaagcaa aaatcttagc taaccattta cttcctaaac cccgttctaa 951840
ataatacatt ggtccccctg ccatttgatt attttcatct ttgatacggt aacgaattgc 951900
taataagcct tcagcatatt ttgtagccat tccaaaaaaa gctgataccc acatccaaaa 951960
taatgctcct ggtcctccgg ccgcaatcgc ggtagctact ccaacaatat ttcctgtccc 952020
gatcgtagaa gatagtgctg tacaaagagc ctgaaaactt gatacatcac cttcatcatt 952080
atcctgtttt ttaaaaatac acgaaaacgc taatttcaat ttcgttaatt gcaacagttt 952140
tagcttacat gtgaaataaa ttccagttcc caacaataga caaataagcg gtaagcccca 952200
tacaagctca tcaatttttg taagtaaatt tgtaataaat tgcataaaaa aactccttct 952260
taaaataatt aagtcggaat taataatgaa aaaaactatt catcccactg tccttttacc 952320
tgagagtttc acctataaat aggcttgctc cttcggtgct taatttaata agtctctcca 952380
gaggttcgtc caatagcgat ccttttacct gaaatcttta attcttcggt gttcaattag 952440
aatctctttc gccattatca tccgatatat acactaagat tatacgctaa ttgtatacaa 952500
ttgcaaatat tttttatttt tgcaataaag tatttgtaaa aacgacattt ctcttctata 952560
ataacaatta tgaaaaaatt aaaatatttt attcctgccc taatttggat gatctttatt 952620
tttataatgt cacacactaa tggtaatgac tcttcaaatc aaagtaattt tattgctgaa 952680
ataattttaa aagttattaa tattgatcgt gatacattaa cttttataat tagaaaagcc 952740
gctcatatga gtgaatatgc aatcttatta ctcttacttt attatgcact aagtaacgtt 952800
atatctaagc atactttatc attatcatta ttagtcacat ttatttatgc ttgtagtgat 952860
gaatttcatc aattgtttat tccagggcgc agtggacaat ttaaagatgt tctaattgac 952920
acttctggtg ccttgatcat gcttatgatc atctttttat ggcaaagaaa aaagaagtct 952980
aaactaatca aataacttta cttaagttat tttgattaat cattagactt cttttcattt 953040
tgcagttttt caatactttc ttttaactta tcaatggcat cattaagtac atcaagatca 953100
ttttgatgat catcgttgtc atcatcactc ggtggcgttg agcgttcttc taagacagct 953160
gaccaagaag agtttgaggc taaaatatca cctacaacat taaaccatgc tcccaaagca 953220
gcttgctcac tcgtagtaaa atcatttgtc aatagatatc ctaagatcac tgcagttcca 953280
gtaaaactat acggatcaag attgggtata tacatggttc acctctccca tattttaata 953340
tatgctaaat aaaaaaaaac ttaggctttt gcatatttaa tatttcgctg cacacactat 953400
tattgggtga aaaaatgaat gataatgtaa aattattaaa ctttatttat caaaactcgc 953460
aaatgggagt tgaaacgatt gagcaattag aaaaaatcgt tgaagataaa gactttaaaa 953520
gatatttaaa agaaaaatat gaaggctatt gtaaaatcca taaagatgct aaagaaaagt 953580
taaatagtca tggatatgac gaaagaggaa ttggttcttt tgaaaaaatt cttacttact 953640
taatgatcaa tatgcaaaca ctgaccgata aatcaactag tcatattgca gaaatgatga 953700
tgattggaag tacgatggga atcatcaatg caattcgtaa tatagctgat tacaatcatg 953760
ctaaaaaaga tattattaag ctcatggaaa cattaaaagc tttcgaagaa aaatcatatg 953820
gagatttgca aaaatttatt taaattgctg ttaatgcagt gctctcctaa gttcaacttt 953880
gtgagggcac tacatatgag gtatattatt tctaattaaa aacagtatta caaataatac 953940
tgtttactat cactaattat aatcaattaa accaaatttc ttaaacactg gtttttgcaa 954000
tttcataaaa atccccatca ttggaccaaa taaaaacatt ccaataatag ttccctctcg 954060
tactgctaaa ggcacatcag taataattac aattataatt actaataaaa ttgaaactac 954120
gtcaacccct tgccgtaaaa catggaattt ctttccagta actccgctaa cagccataca 954180
agctccttcc aaagcaaatg taacaatatc tagaaccatt accattccta ctgcaaaagc 954240
actgacgata tatcccaaaa ttaataatcc aacattcatc caatatgtat taatcgtaaa 954300
attactgtat acttcataca acatgaagtt aacaattagc cctaataaga tgcaaacagg 954360
aatttgtaat agctggatcg gcttaaattt tcttctaagt attgccactt gaacaaagat 954420
acataaaaaa ttacaaaaca taccaattgt tcctacctct atccctgtaa ctaaactccc 954480
tgtctgtgcc aaagcatccc atgcacctac tccaatggcc gctttcaagg ttagagctga 954540
actacatgca acgaccacaa cgccaaacac caaaactatt acccgcttaa acattttaat 954600
tagtacctcg ctttttttgt ataggcatta ttatagcggt ttcaataatc tagtcaacct 954660
attttttaag cgttttcaaa aatagaaaaa gggtaatcta cccttttaaa ataactctac 954720
ttcttgtatg agtgcaatta gctcgcttaa gttattaatt acataatcag caccagcatc 954780
taaatatgct tctttaaccc gttcaattgc acgattccgt tctttaggtg ttaaagcatt 954840
aaattcttct tcgttcaatc ccaaagttga acttccctca atgacaccaa ctgcgattac 954900
ccctgcatta acgccttctt gaatatcaga aattgtatca ccaactttga ttacattttt 954960
tacactgctt atatgcagtt caatcatatt tttaaaaatc atataaggat aagggcgtcc 955020
aaagtgatta gtagcatcag gtgagtacca gcaatcaggt tgatacccct gctccttggc 955080
actttttaat actggctcca tcatcatatc tgtatatcca gtagttgagc caatcttaat 955140
tcccaattct cttagttttg ccacagtttc taaaacatac ggcttaacat ctgtatgttt 955200
tgtaatacct gtcattaatg atgcctcaaa taaatcataa attttatgta tatcctgttc 955260
attaaattca cgatcatatc tagccttaaa tgcttcattc aatactggca tttctaacat 955320
tgttttaata tgatcaatct tcaacatccc cattggttct ctaatttggt cattagttgg 955380
ctctaatcca taattattaa aagcatcttt aaatgcttga acaggagcaa aacaaccata 955440
atcaactgta gttcctgccc aatcgaaaat tactgcttca attctactca ttatgctacc 955500
tccgctaaaa aatctttaat aattgaacat aaatttaata tatctgcttc ataaatttca 955560
ccaatattac caattctgaa tgtttgagca gtagttaact ttcctggata aattgcataa 955620
ccacgtgctt ttatataatc atacatctca ctaaaagcaa attcttttcc ttcaggataa 955680
tagaaagtag taataattgg tccttgataa gctaaatcaa catagctttt cattcccatt 955740
tcagccattt tttcaattag caaacgatta ttatcataat aacgtttact tcgagcagct 955800
attccacctt cttccaacat ctcatctaac gcttttgaaa atgccagtac aacatgggtt 955860
ggtgaagtaa aacgccattt tccatcttta tccatcgttt cccattgatc atataaatcc 955920
aatgataaac ttcttgcttt acctcgacta gctagtaata aatttttatt agcaatcaca 955980
aatgaaaaac caggaactcc ttgaatacac ttgtttgcgc tacttataat aaaatcaatc 956040
cctaattttc ctacctcaat atcaacacca ccaaaactac tcatagcatc aacgataaat 956100
actttatttc tttctttaac tacttttgct acactctcaa tatcatttaa gatcccagat 956160
gttgtctcac tatgaacgat agcaacatga gttatttctt tttcttcatc taatttttca 956220
gcaacagcta ctgcactagg attttcattt tcagcaaact caattatctc atgattaatt 956280
cttgcgtgct cacatatatc tttcattctt tttccataag caccattagc gacaatcaac 956340
agtttttcat tttcgccaat tacacttgta attactgact ctactccaaa agtcccgctt 956400
ccttgcatca gtactacagt atattgctca gctcttacat gagctaattc taataattgg 956460
tccctaattt ttaaagtaat ttttttatag tcatcatccc atgtacaatg atcaaataac 956520
atttcttgct ttactgttgc tgttgttgtt aacggccctg gtgttaataa tttataatct 956580
ttcattttct tctcctactt acattcttct gataattttt gatgtttttc taataattcg 956640
gcagtcaatt tttcactaaa agtttttgga tatgctgact tatttgcact atcactagtt 956700
tctccttggt aaaggggatt agggtaggtt tctaacagct ctttacgtcc actttcaata 956760
atacattgtg ccatcttcat tgctaatttt tgatgttcac taccatcttt atttacgact 956820
gcaactgatt cagtcaaact aaaatttccc tctgttgggt caacaaaatc gattggaagt 956880
ccatcagctt tatcacgtac cgcctgatga cgtagaccaa agccaatcgc tacttctcca 956940
gctcgaactt ttttaattgg gcctgatcct gaatcttcga tatgtgctcc ggcattatca 957000
taaattcctt ttaatacttc ctttgctcca tcttcgccat attcacttac taatgcctga 957060
attaataacc atgctgttga tgaagatgct atatccgtaa ctgagatcat atctttgtat 957120
tctggcttag ctaaatcttt taaacaggtt ggtgtttcaa gactatttgc ttttaattct 957180
tcagtattaa taataatagc cccttcttgt gaagtaatcg gtgtgtaata agatggatat 957240
tcatctaatg cttgagtatc aaaatctaaa tcaacaaaca tctttttttg ttcttgagca 957300
ctatcaagat aaaacgagct cattgttact agatctgcct caatattagt tccttcagcc 957360
aataacttac ctcctaattc agaggttcca aaagtctgaa ataaatactg tccctcataa 957420
ccatttttat ctaatgcatt tttcattgcc gttacagctt catcatcggc atttgaataa 957480
ataacaacct gatcatttga tgaagaacat ccagttaaaa gtgaagcaca aagtaacgaa 957540
ctaactacta acccctttaa taatttcttt ttcattttaa tgttttcctt tctcttcttt 957600
gcttactaaa gtaactaaat actcctttag ctaataaatt aattaataaa atcaagattg 957660
ataaaacaaa gatttcatta aatttagcaa aatgctgtaa ctctttgatc tttgtcgtca 957720
tcaccatcgt ccgcgcccca gcaataaaga taaccgcact aacagtgacc atagcattaa 957780
taaaataata actaaatact tctaaaattg atgaaattgc attaggtgta ataactctaa 957840
taaccgtttt aaaccagcta tcacccatca gtttcgcagt tgtttcaaat gaaccattca 957900
tctttgtcaa tgagtttttc atcattaaat atggcgatga aaagaaatga acgatattac 957960
acaaaataat gatgatataa gtattttgga gcactgtccc agagaacatt aacaagtatg 958020
ctatccctaa taccatacca ggaatagtat tagtagctag agcaatactt tcaattatct 958080
ttttcaaaaa tttatttaaa gtgctccggg cactagccag cgctgctcca tatacgacaa 958140
gtgttcctag taatgctgta aagattgcag tgattaatga attttttatt acccctagca 958200
atgttgcatc actaaaaaca ttaataacat tttgaaaagt aaaactaatt cgatatggcc 958260
actctccaac aaacggcaca attataatta ctataaagac agcaataata attacattaa 958320
tcgttatgct caatgtcccc caaaaccaat cacgaaaacg attctgtttg atttcaatcg 958380
tagagatttt attataacaa atattatatt tttcaagccg atgcaataaa ataatactga 958440
tgattgaagg aatcagcatt gtcattgcaa caactgcccc acctgcaaaa tttggaatac 958500
ttcccaacat cttattgtaa agtacactag caacaacatc atactttcca cccaccgatg 958560
caggaatccc aaaatctgta aaacttagaa agaatgactg aataaaggct gcaaccaaag 958620
ttcctaataa aggtcgaatc aaagtaatca ttaatgtcct aaattcacta tctttcatta 958680
atttggaaac aataataaat tttttatcaa tgtaactaat agcgttatta attaacataa 958740
aagcaatcgg aaaagtatat ataacatacc ctagcatcaa tcccttaaaa ccatatatat 958800
caaataattg aaaaccaaat aactttgtcc acaacccttg ttttccaaac gaatagataa 958860
ttgcaaatcc ataagtaatg gtcggcaaca acattggcag catcgaaaca ttattaatta 958920
tccttttcaa ccctttaaac atattcgtat aatttaaagt gtaagcaaca ataaatgcca 958980
gtattactgt tactagagca ctcactccag aaacaacaaa actatttttt aaagcatgca 959040
taaatcctgt tgtttgataa gtttgtaaat aattatttaa cgttaaacct ccattattat 959100
agaaagattg tattaacagt gacccaattg gtaataacag aaatatccca aaaacagcaa 959160
taacaattat ataaataaac ttgatttctc gatttttatt catttcttta taccaccgga 959220
ctaaacaaag tcataatatt tcttcttttt atttccagct gatttaaaat gaagtcttga 959280
acaaaatcac aacttggatg attaataatt tcctctggtt taccaaactg agatattttt 959340
ccttcattaa taatcaaaac ttgatctgat aatgttaatg cttcctctgg atcatgagta 959400
acaataatag tagttaaatt gtactcctta gcaataatct taattcgctc tttaatagat 959460
tccttgatta ctccatccaa agcgcttaac ggttcatcta aaagaagaat cttaggtttc 959520
attaccattg ttcgagccaa tgcaacccgt tgtttttgtc ctcctgataa ttgatcaatc 959580
tttttatcta aatgcttctc caatcctaac aagtgtatca gctcatctac ttcttcttta 959640
gttgaaatat ccggtttgtt ctttaaacca tacgttatat tttcataggc atttaaatta 959700
ggaaacaaag cataatcttg aaagacaata ttaaagcctc ttttttccat tggaacataa 959760
gttaaatcct cattttcaaa aataattcgt ccactatcaa cctcactaat tcctaaaata 959820
agatttaata aagtagtttt cccacttcct gaaggtccta aaattgaaac aatttgcccc 959880
ttaggtatct ccaaactaag attatttaaa atatttatac catcaaatga cttaacgatc 959940
ctttctagtt ttaacattct ttttcctcct cgaacaactg cattatagct aactaaataa 960000
atttctatct attctttttt ctttaaaact tggttaagaa agcgttaata aaaagaggtg 960060
gtagatgtag aaaaactaca ttcacagctc ctctttttga tatccacgat gtttaattaa 960120
tctactatag tgatctagtt ttttagtgta attatcataa tcactgataa tcacacccat 960180
atagatcata tcgactaatg caatttgagc agttcgtgaa aaaattgcat ctccatacaa 960240
aaactgatca ttacttgttg ataaaacaat atcaccatat cgagttaaca tggtattttc 960300
aaaattaaca atagcaatcg tttgagctcc agcatcttta gcaatcttca agacttcgac 960360
tgtattttta gaatttcctg aataagatat tccaatcgct aaactatccc ttgtcagatt 960420
acttgcatca atactttgga gatagtaatc actatgacaa gtaacactct ttcctaaata 960480
tattaattta gtcattaaat catgagctac acccattgaa ttctcaacag catatattga 960540
aatatgctga ctttgattaa ttaaagctac ggttttttga taattcacta aagaaagaga 960600
ttttaatgca ttttccagca tcgatgttgc tgtagctaca attttacctg gaagatccat 960660
aattttatca tcggcgttta ttgaaaaacc atataaaata tctatattat tttctttatc 960720
ataattttta gctaactcta atttaaattg tttgaaactg tcatagccta tcgctttaac 960780
aaaacgcatt acagttggct gcgatacagc aacttctttg gccaataacg tcattgataa 960840
atcttctagc tttccacaat aatttaatat ataatcagct accttttttt ctgatggacg 960900
taaaatattg tatattgttt ttatcctaaa attcactttg cttagcatat tctctcctgt 960960
agtatttcta ctttattttc tctttttatt tatttttagt ataagcaata ttaaaaaaag 961020
ctactatcat gctagctttt tttatctaaa gaaaaagtaa tttttttgtt aagaaaagaa 961080
aaaaccagat ttttatctgg tttttagatt actaaggaat aattattcct cgcgggttat 961140
caagattata ttctttagcg agcttaggaa aatgattatc aaggtatttt tctaatgctg 961200
tatcatccaa acctttagta agaatgtctt ttatttttaa gggatcatta attgtaattc 961260
ctttacttga taatatctct atgatagaaa caatattttt taaactataa gcctcaatca 961320
ttattttttc atcatctaaa atgatatcta gatccacata ataattaaga tgttgtccga 961380
ctgctaaggt actaccataa gtccaccttt taattattaa tttttcaaga ttagactcca 961440
caattcctgg attatataag cgtgaacaca tcgatacgtt aatctctttg atttcatcga 961500
atgtaatctt tctaatttta ttatcaagtc ttaagattaa ttcttcccca atcaaaagat 961560
actcctcttg ttgatcacct agctggtcaa catacacatt taatcgaaca cgttcacttt 961620
cctcataatt aataactcga ctaattttgt tcagaacatc gtgtttcatt attatccccc 961680
ctttacactt ttattaaaca ctatggtcta aaacaatagt caagaaattc tattcaaata 961740
tttattaatt caataaatac taattttata aaacgctatt tagtatcgaa tatatatact 961800
ccatagattc ttttaattaa tgttttcttt tcatcgaaac tagaattgct agactaggta 961860
ctaagaccaa tctatatata ataatatcat cacctgtagc aattaatctt ttgatcgttg 961920
aaatagcatt tttagcagga tctatcgttt ttagcataag taaaccaaat tgggaaagct 961980
ttaatacttt caatctgttc atcagtaatt acactatctt catacacttc gcaaattggg 962040
aaagctatgg caaaataatc tgagtgtttt aaaatcattt ccattgtcat ataattacca 962100
tttgaacagc ctcaaataat aattcactaa catgctccaa ataactcatc agcataaata 962160
gaattaccaa cttgataatt attattgcct ccatcctcat tgttgaactt tgtagcacta 962220
aaatatatta tatagataaa aaaatccttt gagatataaa tcccaaagga aatattatta 962280
aattccaaat aataaatcta aatatgttgg cattggccaa tattcagcat caatagattc 962340
ttcaagctga tcaactgttt ctctcaatgc ttgcatcatt gcaaaaacat catcgcgcca 962400
tgcaactgcc tgttcaaaaa tttcttcttc agaagcttga gctgcagcaa tattagtttc 962460
taaagttgtc atttgttctt tcattgtctt cactaattta gctaaagcat tagcatcatc 962520
aactaagaaa tcaacatcta aacctgcttc cttagcagca atcacttcag aagatacttt 962580
tgataaataa tcacaaactg ctggataaat ttgagatttg gccattttta acgctgttaa 962640
cccctcaacc tgaatagttt taatatagtt ttctagtaat atctcataac gagatcctaa 962700
ttcaactcta ctataaaccc ctaaacgatc taacatctct aaattctttt cttctttcaa 962760
acattttaaa gcatcaacag tatttttatt attaggaagt ccacgttttg ctgcttcttc 962820
ttcccattct gctgaatatc catcgccatt aaaaataatt cgtttatgag ctaaaacaaa 962880
ttctttaact acatcttcaa atgatttgcc tgattcaatt tcatcagcca ttttttccat 962940
tgcgtcagct aaaattgcat ttaaaatagt atttggtcca gcaacagatt ggcttgaacc 963000
aactgctcta aattcaaact tatttccagt aaacgcaaat ggtgatgtac gattacggtc 963060
tgtattgtct tttgagaaag ttggtactac tgatactcca gtggcaaaac gtgccgcatc 963120
agatttgcta gttttcttac cttcacaaat ttctgctaaa agagcatcta actcttcccc 963180
taagaacata gaaataattg caggtggtgc ttcatttgct cctaaacggt gatcgtttcc 963240
agcgctggca atactcatcc gtaataaatc agcataatca tcaacagctt taatcgtaca 963300
tgcaagcgtt gcaataaatg gtttattttc agcaggatta gcacctggat tgaataaatt 963360
aatacctgta ttagtaatga ctgaccagtt atcatgttta ccagaaccat ttaccccagc 963420
aaatggcttt tcatgtaata agcagcgtaa accatgcttt ttagcaatat cttgcataat 963480
ttgcattaat aaatggttat tatcagtagt aatatttact tttgaatata cgcatgctac 963540
ttcatgttgt gccggtgcaa cttcattatg ttttgttttt gaaggaattc catatttcca 963600
taattcatga tctaaatctt tcataaaggc agacacttta cgtttaagac taccaaagta 963660
atgatcttct aattcttgtc ctttcggcgc cattgcccca aatagagtac gtccagttaa 963720
ctttaaatcc attctttctt ggtaatattt atcatcaact aagaaatatt cttgttcagc 963780
cccaacagat gcagtaactt tagtaattcc tttttcacca agcaaaggca ataatcgaca 963840
tgcagcttta gataatgcat cacaagatcg taacaacggt gtctttttat ctaatgcttc 963900
tccagtatat gaacaaaaca aagttggaat atataaagat ccatctttaa caaatgccgg 963960
tgatgtacaa tcccatgcag tatagcctct cgcttcaaat gttgctcgta atcctccaga 964020
cgggaaagac gatgcatcag gttcaccttt tcttaatgtt tttccactaa attctaatac 964080
tgctttacaa ccgtcaggtt ccaaaaaagc atcatgtttt tcagctgtca aaccagtcat 964140
tggcataaac caatgggtaa aatgtgttgc accattttct aatgcccaga ttttcattgc 964200
attagcaatt actgttgcgc attctttaga taattcttca ccattatcta aagactcatg 964260
gaatgccttg taaatagatt taggaatccg ttctttcatt acatcatcac taaatgccaa 964320
gcatccgtaa tcttctaata acttattcat ttccattcta agttccccct tgttagtttc 964380
taaacaacac ataaccatac acttaatata tgtttatatg ccgttattat acagttactt 964440
tatttaggtg tcaatatcta tatgatattt ttttatcatt ttgttaattc tttattaaaa 964500
tgataaatta tttataactg tttacttaaa gatacttatt acaactaagt aatattccat 964560
ttttacaaaa gaaaaagatg cttattcagc atccatattt gcttttttag cttcttcttt 964620
caaagctctt ttgcgtttct tttcatatga tctatgagta gctgcatatt cagtacattg 964680
cacatgaatt cttttattag cagctacaat cgcttcaata aatcccattc tatcttttgg 964740
tgttacaaca aatctttttt tattttcagc ataaatttct aatgcccgtg gactagttat 964800
aagttttgtc atctttggta caggatcaca aattgtttca catgtcataa tattaatttc 964860
tttatcttta ccaacacggc gattaattat caatgttcta cgattaattg tatatttata 964920
tggtcgccat aaagaaaaat atgcaataat taataatcca caaatagcac acactatcgc 964980
aggtaccatt tgtccaatta taaataaata aactacatat accatataaa agatttcaaa 965040
gtatagtatt gcgggattca atttaatttt aaactctttt tctttcataa taacctctct 965100
ttttcctcaa cttcatcatt ataacgtatc ttaaatacta taacaattat aaattatcaa 965160
tcattgataa cttatagtta ctatattatt aaataaagaa agacgggaaa cccgtctttc 965220
gattatcaaa caagtttgtt gaattattct gcagcttctg cagcttgttt gttttgatat 965280
ctttcataag caattaagaa tggtacgtat actaagatag at 965322
Claims (39)
- IL-17 또는 Th17 경로에 의해 매개된 질환 또는 병태의 치료 또는 예방하는 방법에 사용하기 위한, 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 하기로 이루어진 군으로부터 선택된 질환 또는 병태의 치료 또는 예방의 방법에 사용하기 위한 것인, 조성물: 포도막염; 암, 예컨대 유방암, 폐암, 간암, 결장암, 또는 난소암; 다발성 경화증; 관절염, 예컨대 류마티스성 관절염, 골관절염, 건선성 관절염, 또는 유년성 특발성 관절염; 시신경척수염 (데빅병); 강직 척추염; 척추관절염; 건선; 전신 홍반성 낭창; 염증성 장 질환, 예컨대 크론병 또는 궤양성 대장염; 소아지방변증; 천식, 예컨대 알러지성 천식 또는 호중구성 천식; 만성 폐쇄성 폐 질환 (COPD); 공막염; 혈관염; 베체트병; 죽상경화증; 아토피 피부염; 폐공기증; 치주염; 알러지성 비염; 및 동종이식편 거부반응.
- 청구항 2에 있어서, 상기 조성물이 포도막염을 치료 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 3에 있어서, 상기 조성물이 포도막염에서 망막 손상을 감소 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 2에 있어서, 상기 조성물이 폐암, 유방암 또는 간암과 같은 암을 치료 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 5에 있어서, 상기 조성물이 종양 크기를 감소, 종양 성장을 감소, 전이를 예방 또는 혈관신생을 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 2에 있어서, 상기 조성물이 호중구성 천식 또는 알러지성 천식과 같은 천식을 치료 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 7에 있어서, 상기 조성물이 천식의 치료에서 호중구증가증 또는 호산구증가증을 감소하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 2에 있어서, 상기 조성물이 류마티스성 관절염을 치료 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 9에 있어서, 상기 조성물이 류마티스성 관절염에서 관절 팽윤을 감소시키는 방법에 사용하기 위한 것인, 조성물.
- 청구항 2에 있어서, 상기 조성물이 다발성 경화증을 치료 또는 예방하는 방법에 사용하기 위한 것인, 조성물.
- 청구항 11에 있어서, 상기 조성물이 질환 발병률 또는 질환 중증도를 감소시키는 방법에서 사용하기 위한 것인, 조성물.
- 청구항 1 내지 청구항 12 중 어느 한 항에 있어서, 상기 조성물이 IL-17 또는 Th17 경로에 의해 매개되는 질병 또는 병태의 치료 또는 예방에서 IL-17 생성을 감소시키거나 Th17 세포 분화를 감소시키는 방법에 사용하기 위한 것인, 조성물.
- 청구항 1 내지 청구항 13 중 어느 한 항에 있어서, 상기 조성물이 증가된 IL-17 수준 또는 Th17 세포를 갖는 환자에서 사용하기 위한 것인, 조성물.
- 청구항 1 내지 청구항 14 중 어느 한 항에 있어서, 상기 박테리아 균주가 에리시펠라토클로스트리디움 라모숨의 것인, 조성물
- 청구항 1 내지 청구항 14 중 어느 한 항에 있어서, 상기 박테리아 균주가 에리시펠라토클로스트리디움 라모숨의 박테리아 균주의 16s rRNA 서열에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는, 조성물.
- 청구항 1 내지 청구항 14 중 어느 한 항에 있어서, 상기 박테리아 균주가 서열 식별 번호: 1, 2 또는 3에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖는, 조성물.
- 청구항 17에 있어서, 상기 박테리아 균주가 서열 식별 번호: 3에 적어도 95%, 96%, 97%, 98%, 99%, 99.5% 또는 99.9% 동일한 16s rRNA 서열을 갖거나, 상기 박테리아 균주가 서열 식별 번호: 3으로 표시되는 16s rRNA 서열을 갖는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 류마티스성 관절염의 치료 또는 예방의 방법에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 천식, 예컨대 호중구성 천식 또는 알러지성 천식의 치료 또는 예방의 방법에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 다발성 경화증의 치료 또는 예방의 방법에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 포도막염의 치료 또는 예방의 방법에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는, 조성물.
- 청구항 1에 있어서, 상기 조성물이 암의 치료 또는 예방의 방법에 사용하기 위한, 종 에리시펠라토클로스트리디움 라모숨의 박테리아 균주를 포함하는, 조성물.
- 청구항 1 내지 청구항 23 중 어느 한 항에 있어서, 상기 조성물이 경구 투여를 위한 것인, 조성물.
- 청구항 1 내지 청구항 24 중 어느 한 항에 있어서, 상기 조성물이 하나 이상의 약학적으로 허용가능한 부형제 또는 담체를 포함하는, 조성물.
- 청구항 1 내지 청구항 25 중 어느 한 항에 있어서, 상기 박테리아 균주가 동결건조되는, 조성물.
- 청구항 1 내지 청구항 26 중 어느 한 항에 있어서, 상기 박테리아 균주가 생존가능하고 장에서 부분적으로 또는 전적으로 군집할 수 있는, 조성물.
- 청구항 1 내지 청구항 27 중 어느 한 항에 있어서, 상기 조성물이 속 에리시펠라토클로스트리디움의 단일 균주를 포함하는, 조성물.
- 청구항 1 내지 청구항 28 중 어느 한 항에 있어서, 미생물 컨소시엄의 일부로서 에리시펠라토클로스트리디움 박테리아 균주를 포함하는, 조성물.
- 청구항 1 내지 청구항 29 중 어느 한 항의 용도를 위한, 청구항 1 내지 청구항 29 중 어느 한 항의 조성물을 포함하는 식품.
- 청구항 1 내지 청구항 30 중 어느 한 항의 용도를 위한, 청구항 1 내지 청구항 30 중 어느 한 항의 조성물을 포함하는 백신 조성물.
- 속 에리시펠라토클로스트리디움의 박테리아 균주를 포함하는 조성물을 필요로 하는 환자에 투여하는 것을 포함하는, IL-17 또는 Th17 경로에 의해 매개된 질환 또는 병태의 치료 또는 예방 방법.
- 에리시펠라토클로스트리디움 라모숨 NCIMB 42688로서 기탁된 균주 MRX027, 또는 이의 유도체의, 세포.
- 청구항 33의 세포를 포함하는, 조성물.
- 청구항 34에 있어서, 약학적으로 허용가능한 캐리어 또는 부형제를 포함하는, 조성물.
- 에리시펠라토클로스트리디움 라모숨 NCIMB 42688로서 기탁된 균주 MRX027, 또는 이의 유도체의, 생물학적으로 순수한 배양물.
- 치료법에 사용하기 위한, 에리시펠라토클로스트리디움 라모숨 NCIMB 42688로서 기탁된 균주 MRX027, 또는 이의 유도체의, 세포.
- 청구항 37에 있어서, 상기 세포가 청구항 1 내지 청구항 14 중 어느 한 항에 있어서 한정된 방법에 사용하기 위한 것인, 세포.
- 치료법에 사용하기 위한, 임의의 다른 속으로부터 박테리아를 함유하지 않거나 또 다른 속으로부터 박테리아의 최소한 또는 생물학적으로 무관한 양만을 포함하는, 속 에리시펠라토클로스트리디움의 하나 이상의 박테리아 균주를 포함하는, 조성물.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023068857A1 (ko) * | 2021-10-20 | 2023-04-27 | 주식회사 고바이오랩 | 항암 활성을 갖는 신규 박테리아 균주 및 이를 이용한 암의 완화, 예방 또는 치료용 조성물 |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
CN108676774B (zh) * | 2011-12-01 | 2023-05-09 | 国立大学法人东京大学 | 诱导调节性t细胞的增殖或积累的人源细菌 |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
ME02997B (me) | 2014-12-23 | 2018-10-20 | 4D Pharma Res Ltd | Soj bacteroides thetaiotaomicron i njegova upotreba u smanjenju inflamacije |
WO2016102951A1 (en) | 2014-12-23 | 2016-06-30 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
MD3307288T2 (ro) | 2015-06-15 | 2019-12-31 | 4D Pharma Res Ltd | Compoziții care conțin tulpini bacteriene |
CN115364122A (zh) | 2015-06-15 | 2022-11-22 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
PL3206700T3 (pl) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Kompozycje zawierające szczepy bakteryjne |
EA034677B1 (ru) | 2015-11-20 | 2020-03-05 | 4Д Фарма Рисёрч Лимитед | Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum |
GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
DK3313423T3 (da) | 2016-03-04 | 2019-05-20 | 4D Pharma Plc | Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet |
US11260083B2 (en) * | 2016-03-15 | 2022-03-01 | The Regents Of The University Of Michigan | Compositions and methods for treating and preventing graft versus host disease |
US9999641B2 (en) | 2016-06-14 | 2018-06-19 | Vedanta Biosciences, Inc. | Treatment of clostridium difficile infection |
TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
EP3606325B1 (en) | 2017-04-03 | 2024-09-04 | Gusto Global, LLC | Rational design of microbial-based biotherapeutics |
LT3630136T (lt) | 2017-05-22 | 2021-06-10 | 4D Pharma Research Limited | Kompozicijos, apimančios bakterines padermes |
WO2018215782A1 (en) | 2017-05-24 | 2018-11-29 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
IL283973B (en) | 2017-06-14 | 2022-08-01 | 4D Pharma Res Ltd | Preparations containing bacterial strains |
HUE052258T2 (hu) | 2017-06-14 | 2021-04-28 | 4D Pharma Res Ltd | Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása |
EP3638271B1 (en) | 2017-06-14 | 2020-10-14 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
EP3476396A1 (en) * | 2017-10-31 | 2019-05-01 | Institut Gustave Roussy | Bacterial and cell compositions for the treatment of colorectal cancer and methods for assessing a prognosis for patients having the same |
US20220000949A1 (en) * | 2018-09-25 | 2022-01-06 | National Cerebral And Cardiovascular Center | Antitumor effect potentiator |
WO2020118232A1 (en) * | 2018-12-07 | 2020-06-11 | President And Fellows Of Harvard College | Identification of gut bacteria that promote an anti-tumor response to immunotherapy |
IL265735A (en) * | 2019-03-31 | 2019-05-30 | Biomica | A microbial consortium and its uses |
CN110664835B (zh) * | 2019-12-09 | 2020-03-24 | 中国科学院烟台海岸带研究所 | 含壳寡糖、菊糖、鞣花酸两种或以上的复合物及应用 |
JP2024097095A (ja) * | 2021-03-23 | 2024-07-18 | 国立大学法人大阪大学 | 炎症性腸疾患を検査する方法 |
CN117625500B (zh) * | 2024-01-24 | 2024-04-02 | 中山大学 | 一种胃梭菌及其应用 |
Family Cites Families (307)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
NL8300698A (nl) | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
US5443826A (en) | 1988-08-02 | 1995-08-22 | Borody; Thomas J. | Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli |
KR100225087B1 (ko) | 1990-03-23 | 1999-10-15 | 한스 발터라벤 | 피타아제의 식물내 발현 |
AU639570B2 (en) | 1990-05-09 | 1993-07-29 | Novozymes A/S | A cellulase preparation comprising an endoglucanase enzyme |
GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
US5443951A (en) | 1992-07-20 | 1995-08-22 | Kabushiki Kaisha Yakult Honsha | Species-specific oligonucleotides for bifidobacteria and a method of detection using the same |
JPH08504327A (ja) | 1992-12-10 | 1996-05-14 | ギスト ブロカデス ナムローゼ フェンノートシャップ | 糸状菌における異種タンパクの生産 |
US5741665A (en) | 1994-05-10 | 1998-04-21 | University Of Hawaii | Light-regulated promoters for production of heterologous proteins in filamentous fungi |
AUPM823094A0 (en) | 1994-09-16 | 1994-10-13 | Goodman Fielder Limited | Probiotic compositions |
RU2078815C1 (ru) | 1995-01-17 | 1997-05-10 | Московский научно-исследовательский институт эпидемиологии и микробиологии им.Г.Н.Габричевского | Штамм бактерий bifidobacterium breve, используемый для получения бактерийных лечебно-профилактических бифидосодержащих препаратов |
JPH08259450A (ja) | 1995-03-17 | 1996-10-08 | Nichinichi Seiyaku Kk | インターフェロン産生増強剤 |
US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
AUPN698495A0 (en) | 1995-12-06 | 1996-01-04 | Pharma Pacific Pty Ltd | Improved therapeutic formulation and method |
SE508045C2 (sv) | 1996-02-26 | 1998-08-17 | Arla Ekonomisk Foerening | Adhesionsinhibitorer, preparat innehållande desamma och förfarande för framställning därav |
JP4282763B2 (ja) | 1996-03-20 | 2009-06-24 | ザ、ユニバーシティ、オブ、ニュー、サウス、ウェイルズ | 消化管内の微生物個体数の変更 |
WO1997035956A1 (en) | 1996-03-27 | 1997-10-02 | Novo Nordisk A/S | Alkaline protease deficient filamentous fungi |
US6033864A (en) | 1996-04-12 | 2000-03-07 | The Regents Of The University Of California | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens |
WO1998043081A1 (en) | 1997-03-26 | 1998-10-01 | Ligand Pharmaceuticals Incorporated | Treatment of gastrointestinal disease with ppar modulators |
SE511524C2 (sv) | 1997-06-02 | 1999-10-11 | Essum Ab | Lactobacillus casei rhamnosus-stam samt farmaceutisk beredning för bekämpning av patogena tarmbakterier |
US5925657A (en) | 1997-06-18 | 1999-07-20 | The General Hospital Corporation | Use of PPARγ agonists for inhibition of inflammatory cytokine production |
AUPO758297A0 (en) | 1997-06-27 | 1997-07-24 | Rowe, James Baber | Control of acidic gut syndrome |
US5951977A (en) | 1997-10-14 | 1999-09-14 | The United States Of America, As Represented By The Secretary Of Agriculture | Competitive exclusion culture for swine |
IT1298918B1 (it) | 1998-02-20 | 2000-02-07 | Mendes Srl | Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche |
DE19826928A1 (de) | 1998-06-17 | 1999-12-23 | Novartis Consumer Health Gmbh | Arzneimittel, lebensfähige anaerobe Bakterien enthaltend, die die Sulfatreduktion sulfatreduzierender Bakterien hemmen |
ID29150A (id) | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
US7090973B1 (en) | 1999-04-09 | 2006-08-15 | Oscient Pharmaceuticals Corporation | Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics |
JP2003508389A (ja) | 1999-08-27 | 2003-03-04 | エリ リリー アンド カンパニー | ビアリール−オキサ(チア)ゾール誘導体およびそのpparモジュレーターとしての使用 |
BR0108164B1 (pt) | 2000-02-08 | 2014-06-17 | Dsm Ip Assets Bv | Uso de pelo menos uma protease estável em ácido, processo para melhorar o valor nutritivo de um alimento para animal, aditivo de alimento para animal, composição de alimento para animal, e, processo para tratar proteínas vegetais para uso em alimento para animal. |
FR2808689B1 (fr) | 2000-05-11 | 2004-09-03 | Agronomique Inst Nat Rech | Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs |
US20020013270A1 (en) | 2000-06-05 | 2002-01-31 | Bolte Ellen R. | Method for treating a mental disorder |
AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
DE10101793A1 (de) | 2001-01-17 | 2002-08-01 | Manfred Nilius | Verwendung von SLPI zur Behandlung chronisch-entzündlicher Darmerkrankungen |
EP1227152A1 (en) | 2001-01-30 | 2002-07-31 | Société des Produits Nestlé S.A. | Bacterial strain and genome of bifidobacterium |
KR100437497B1 (ko) | 2001-03-07 | 2004-06-25 | 주식회사 프로바이오닉 | 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제 |
EP1379552B2 (en) | 2001-04-20 | 2014-11-19 | The Institute for Systems Biology | Toll-like receptor 5 ligands and methods of use |
EP1260227A1 (en) | 2001-05-23 | 2002-11-27 | Societe Des Produits Nestle S.A. | Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria |
US20030092163A1 (en) | 2001-07-26 | 2003-05-15 | Collins John Kevin | Probiotic bifidobacterium strains |
MXPA04001999A (es) | 2001-09-05 | 2004-07-16 | Vsl Pharmaceuticals Inc | Bacterias de acido lactico que comprende dinucleotidos de citosina-guanina no metilados para usarse en terapia. |
GB0127916D0 (en) | 2001-11-21 | 2002-01-16 | Rowett Res Inst | Method |
AU2002346504A1 (en) | 2001-11-27 | 2003-06-10 | Astrazeneca Ab | Therapeutic protein and treatments |
CA2476755C (en) | 2001-12-17 | 2014-08-26 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of inflammatory bowel disease |
DE10206995B4 (de) | 2002-02-19 | 2014-01-02 | Orthomol Pharmazeutische Vertriebs Gmbh | Mikronährstoffkombinationsprodukt mit Pro- und Prebiotika |
JP2003261453A (ja) | 2002-03-11 | 2003-09-16 | Nippon Berumu Kk | E.フェカリスからなる抗腫瘍剤及び放射線防護剤 |
WO2004003235A2 (en) | 2002-06-28 | 2004-01-08 | Puleva Biotech, S.A. | Probiotic strains, a process for the selection of them, compositions thereof, and their use |
EP1481681A1 (en) | 2003-05-30 | 2004-12-01 | Claudio De Simone | Lactic acid bacteria combination and compositions thereof |
AU2003247193A1 (en) | 2003-07-23 | 2005-02-04 | M.D.Lab Corp. | Acid tolerant probiotic lactobacillus plantarum probio-38 that can suppress the growth of pathogenic microorganism and tge coronavirus |
US7485325B2 (en) | 2003-08-06 | 2009-02-03 | Gayle Dorothy Swain | Animal food supplement compositions and methods of use |
JP4683881B2 (ja) | 2003-08-27 | 2011-05-18 | 有限会社アーク技研 | 抗腫瘍活性剤 |
US8192733B2 (en) | 2003-08-29 | 2012-06-05 | Cobb & Associates | Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions |
US20050163764A1 (en) | 2003-09-22 | 2005-07-28 | Yale University | Treatment with agonists of toll-like receptors |
GB0323039D0 (en) | 2003-10-01 | 2003-11-05 | Danisco | Method |
ES2314461T3 (es) | 2003-10-24 | 2009-03-16 | N.V. Nutricia | Composicion simbiotica para bebes. |
CA2550106A1 (en) | 2003-12-17 | 2005-06-30 | N.V. Nutricia | Lactic acid producing bacteria and lung function |
ES2235642B2 (es) | 2003-12-18 | 2006-03-01 | Gat Formulation Gmbh | Proceso de multi-microencapsulacion continuo para la mejora de la estabilidad y almacenamiento de ingredientes biologicamente activos. |
WO2005093049A1 (en) | 2004-03-22 | 2005-10-06 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Cellular and viral inactivation |
JP2007535924A (ja) | 2004-05-07 | 2007-12-13 | − グスタフ ユングレン、ハンス | ワクチン用アジュバントとしてのフラジェリンの使用 |
ES2286558T5 (es) | 2004-08-24 | 2013-10-15 | N.V. Nutricia | Composición nutritiva que comprende transgalactooligosacáridos indigeribles y sacáridos de galactosa digeribles |
US20060062742A1 (en) | 2004-09-21 | 2006-03-23 | The Procter & Gamble Company | Compositions for reduction of human malodor |
KR100468522B1 (ko) | 2004-10-12 | 2005-01-31 | 주식회사 프로바이오닉 | 코로나바이러스와 돼지 써코바이러스 2형의 생육을 억제하는 신규한 내산성 프로바이오틱 엔테로코커스훼시움 프로바이오-63 |
ITMI20042189A1 (it) | 2004-11-16 | 2005-02-16 | Anidral Srl | Composizione a base di batteri probiotici e suo uso nella prevenzione e-o nel trattamento di patologie e-o infezioni respiratorie e nel miglioramento della funzionalita' intestinale |
ES2524344T3 (es) | 2005-02-28 | 2014-12-05 | N.V. Nutricia | Composición nutritiva con probióticos |
WO2006102536A2 (en) | 2005-03-23 | 2006-09-28 | University Of Southern California | Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth |
WO2006102350A1 (en) | 2005-03-23 | 2006-09-28 | Washington University In St. Louis | The use of archaea to modulate the nutrient harvesting functions of the gastrointestinal microbiota |
JP2006265212A (ja) | 2005-03-25 | 2006-10-05 | Institute Of Physical & Chemical Research | Il−21産生誘導剤 |
EP1714660A1 (en) | 2005-04-21 | 2006-10-25 | N.V. Nutricia | Uronic acid and probiotics |
US8603461B2 (en) | 2005-04-26 | 2013-12-10 | TEAGASC—The Agriculture and Food Development Authority | Probiotic composition suitable for animals |
US7572474B2 (en) | 2005-06-01 | 2009-08-11 | Mead Johnson Nutrition Company | Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
US8075934B2 (en) | 2008-10-24 | 2011-12-13 | Mead Johnson Nutrition Company | Nutritional composition with improved digestibility |
JP2007084533A (ja) | 2005-08-24 | 2007-04-05 | Prima Meat Packers Ltd | 免疫応答調節組成物及び該組成物を有効成分とする食品 |
US7625704B2 (en) | 2005-08-31 | 2009-12-01 | Fred Hutchinson Cancer Research Center | Methods and compositions for identifying bacteria associated with bacteria vaginosis |
CN101296706B (zh) * | 2005-09-01 | 2011-11-30 | 先灵公司 | Il-23和il-17拮抗剂治疗自身免疫性眼部炎性疾病的用途 |
US20090028840A1 (en) | 2005-09-23 | 2009-01-29 | Gwangju Institute Of Sciecne And Technology | Compositions For Preventing Or Treating Arthritis Comprising Lactic Acid Bacteria and Collangen As Active Ingredients |
EP1776877A1 (en) | 2005-10-21 | 2007-04-25 | N.V. Nutricia | Method for stimulating the intestinal flora |
MY144556A (en) | 2005-10-24 | 2011-09-30 | Nestec Sa | Dietary fiber formulation and method of administration |
JP2007116991A (ja) | 2005-10-28 | 2007-05-17 | Eternal Light General Institute Inc | 機能性食品 |
US8889149B2 (en) | 2006-02-16 | 2014-11-18 | Wayne State University | Use of flagellin to prevent and treat gram negative bacterial infection |
JP5031249B2 (ja) | 2006-03-22 | 2012-09-19 | 学校法人北里研究所 | 炎症抑制作用のある菌体含有組成物 |
CA2652559A1 (en) | 2006-05-18 | 2007-11-29 | Biobalance Llc | Biotherapeutic compositions and uses thereof |
CA2655665A1 (en) | 2006-05-26 | 2007-12-06 | Nestec S.A. | Methods of use and nutritional compositions of touchi extract |
US8691213B2 (en) | 2006-08-04 | 2014-04-08 | SHS International | Protein free formula |
WO2008031438A2 (en) | 2006-09-13 | 2008-03-20 | Region Hovedstaden V/Gentofte Hospital | Treatment of asthma, eczema and/or allergy using non-pathogenic organisms |
US20080069861A1 (en) | 2006-09-19 | 2008-03-20 | National Starch And Chemical Investment Holding Corporation | Probiotic/Non-Probiotic Combinations |
KR20120038021A (ko) | 2006-10-27 | 2012-04-20 | 화이자 프로덕츠 인코포레이티드 | 하이드록시프로필 메틸 셀룰로스 경질 캡슐 및 이의 제조 방법 |
WO2008053444A2 (en) | 2006-11-01 | 2008-05-08 | The Procter & Gamble Company | Treating a respiratory condition with bifidobacterium |
PL1920781T3 (pl) | 2006-11-10 | 2015-06-30 | Glycotope Gmbh | Kompozycje zawierające core-1-dodatnie mikroorganizmy i ich zastosowanie w leczeniu lub profilaktyce nowotworów |
WO2008064489A1 (en) | 2006-12-01 | 2008-06-05 | Mcmaster University | Probiotics to inhibit inflammation |
DE102006062250A1 (de) | 2006-12-22 | 2008-06-26 | Roland Saur-Brosch | Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden |
JP2008195635A (ja) | 2007-02-09 | 2008-08-28 | Crossfield Bio Inc | 馬用乳酸菌製剤 |
MX2009008875A (es) | 2007-02-28 | 2009-08-28 | Mead Johnson Nutrition Co | Producto que contiene probiotico inactivado para niños o infantes. |
JP5538209B2 (ja) | 2007-03-28 | 2014-07-02 | アリメンタリー・ヘルス・リミテッド | プロバイオティック性のビフィドバクテリウム菌株 |
AU2008231467A1 (en) | 2007-03-28 | 2008-10-02 | Alimentary Health Limited | Probiotic Bifidobacterium strains |
AU2008245685B2 (en) | 2007-04-24 | 2013-06-27 | Kemin Industries, Inc. | Broad-spectrum antibacterial and antifungal activity of Lactobacillus johnsonii D115 |
EP1997499A1 (en) | 2007-05-31 | 2008-12-03 | Puleva Biotech, S.A. | Mammalian milk microorganisms, compositions containing them and their use for the treatment of mastitis |
EP1997906A1 (en) | 2007-06-01 | 2008-12-03 | Friesland Brands B.V. | Lactobacillus |
EP1997907A1 (en) | 2007-06-01 | 2008-12-03 | Friesland Brands B.V. | Bifidobacteria |
EP1997905A1 (en) | 2007-06-01 | 2008-12-03 | Friesland Brands B.V. | Nucleic acid amplification |
WO2008153377A1 (en) | 2007-06-15 | 2008-12-18 | N.V. Nutricia | Nutrition with non-viable bifidobacterium and non-digestible oligosaccharide |
EP2179028B1 (en) | 2007-06-27 | 2014-08-13 | Laboratorios Ordesa, S.l. | A novel strain of bifidobacterium and active peptides against rotavirus infections |
HUP0700552A2 (en) | 2007-08-27 | 2009-03-30 | Janos Dr Feher | Method and composition inhibiting inflammation |
WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
US20100284979A1 (en) | 2007-10-01 | 2010-11-11 | University College Cork, National University Of Ireland, Cork | Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria |
DK2203551T3 (da) | 2007-10-20 | 2013-10-28 | Univ Liege | Bifidobakterieart |
ES2473625T3 (es) | 2007-10-26 | 2014-07-07 | Brenda E. Moore | Composición probi�tica y métodos para inducir y mantener la pérdida de peso |
EP2065048A1 (en) | 2007-11-30 | 2009-06-03 | Institut Pasteur | Use of a L. casei strain, for the preparation of a composition for inhibiting mast cell activation |
US9119414B2 (en) | 2007-12-07 | 2015-09-01 | N.V. Nutricia | Bifidobacterium for dust mite allergy |
WO2009079564A2 (en) | 2007-12-17 | 2009-06-25 | Emory University | Immunogenic compositions and methods of use thereof |
JP2011510684A (ja) | 2008-02-06 | 2011-04-07 | ザ プロクター アンド ギャンブル カンパニー | 呼吸器状態に対する免疫反応を強化するための組成物、方法、及びキット |
WO2009128950A2 (en) | 2008-04-18 | 2009-10-22 | Vaxinnate Corporation | Deletion mutants of flagellin and methods of use |
MX2008006546A (es) | 2008-05-21 | 2009-11-23 | Sigma Alimentos Sa De Cv | Bifidobacteria productora de ácido fólico, composición alimenticia y uso de la bifidobacteria. |
CN101590081A (zh) | 2008-05-28 | 2009-12-02 | 青岛东海药业有限公司 | 凸腹真杆菌和两形真杆菌制剂及其应用 |
CN102940652B (zh) | 2008-05-28 | 2015-03-25 | 青岛东海药业有限公司 | 两形真杆菌制剂及其应用 |
WO2009149149A1 (en) | 2008-06-04 | 2009-12-10 | Trustees Of Dartmouth College | Prevention or treatment of immune-relevant disease by modification of microfloral populations |
EP2133088A3 (en) | 2008-06-09 | 2010-01-27 | Nestec S.A. | Rooibos and inflammation |
WO2009151315A1 (en) | 2008-06-13 | 2009-12-17 | N.V. Nutricia | Nutritional composition for infants delivered via caesarean section |
WO2009154463A2 (en) | 2008-06-20 | 2009-12-23 | Stichting Top Institute Food And Nutrition | Butyrate as a medicament to improve visceral perception in humans |
EP2138186A1 (en) | 2008-06-24 | 2009-12-30 | Nestec S.A. | Probiotics, secretory IgA and inflammation |
WO2010002241A1 (en) | 2008-06-30 | 2010-01-07 | N.V. Nutricia | Nutritional composition for infants delivered via caesarean section |
KR101017448B1 (ko) | 2008-09-18 | 2011-02-23 | 주식회사한국야쿠르트 | 대장의 건강 증진 효능을 갖는 비피도박테리움 롱검 에이취와이8004 및 이를 유효성분으로 함유하는 제품 |
US8137718B2 (en) | 2008-09-19 | 2012-03-20 | Mead Johnson Nutrition Company | Probiotic infant products |
US20100074870A1 (en) | 2008-09-19 | 2010-03-25 | Bristol-Myers Squibb Company | Probiotic infant products |
KR101057357B1 (ko) | 2008-09-22 | 2011-08-17 | 광주과학기술원 | 유산균 및 콜라겐을 유효성분으로 포함하는 관절염 예방 또는 치료용 약제학적 조성물 및 식품 조성물 |
WO2010037408A1 (en) | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
US20110223137A1 (en) | 2008-12-05 | 2011-09-15 | Nestec S.A. | Compositions for use in low-birth weight infants |
CA2746805A1 (en) | 2008-12-19 | 2010-06-24 | Nestec S.A. | Prevention and treatment of rotavirus diarrhoea |
IT1392672B1 (it) | 2009-01-12 | 2012-03-16 | Wyeth Consumer Healthcare S P A | Composizioni comprendenti componenti probiotici e prebiotici e sali minerali, con lactoferrina |
BRPI1013688A8 (pt) | 2009-03-05 | 2017-02-14 | Abbott Lab | Proteínas de ligação de il-17. |
JP5710876B2 (ja) | 2009-03-26 | 2015-04-30 | クロスフィールドバイオ株式会社 | 新規ビフィドバクテリウム属微生物およびその利用 |
US8816067B2 (en) | 2009-05-07 | 2014-08-26 | Tate & Lyle Ingredients France SAS | Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans |
EP2251022A1 (en) | 2009-05-11 | 2010-11-17 | Nestec S.A. | Non-replicating micro-organisms and their immune boosting effect |
CA2761444C (en) | 2009-05-11 | 2018-04-24 | Nestec S.A. | Lactobacillus johnsonii la1 ncc533 (cncm i-1225) and immune disorders |
EP2251020A1 (en) | 2009-05-11 | 2010-11-17 | Nestec S.A. | Short-time high temperature treatment generates microbial preparations with anti-inflammatory profiles |
KR20100128168A (ko) | 2009-05-27 | 2010-12-07 | 중앙대학교 산학협력단 | 공액 리놀레산 생산능이 우수한 신규한 균주 |
US20100311686A1 (en) | 2009-06-03 | 2010-12-09 | Kasper Lloyd H | Nutraceutical composition and methods for preventing or treating multiple sclerosis |
WO2010143940A1 (en) | 2009-06-12 | 2010-12-16 | N.V. Nutricia | Synergistic mixture of beta-galacto-oligosaccharides with beta-1,3 and beta-1,4/1,6 linkages |
EP2443259A4 (en) | 2009-06-16 | 2012-10-10 | Univ Columbia | BIOMARKERS FOR AUTISM AND USES THEREOF |
WO2011005756A1 (en) | 2009-07-06 | 2011-01-13 | Puretech Ventures, Llc | Delivery of agents targeted to microbiota niches |
CA2770062A1 (en) | 2009-08-18 | 2011-02-24 | Nestec S.A. | A nutritional composition comprising bifidobacterium longum strains and reducing food allergy symptoms, especially in infants and children |
US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
CA2775050C (en) | 2009-09-23 | 2020-07-14 | Thomas Julius Borody | Therapy for enteric infections |
EP2308498A1 (en) | 2009-09-30 | 2011-04-13 | Nestec S.A. | Administration of Bifidobacterium breve during infancy to prevent inflammation later in life |
EP2486143A1 (en) | 2009-10-05 | 2012-08-15 | AAK Patent B.V. | Methods for diagnosing irritable bowel syndrome |
EP3144004A1 (en) | 2009-10-06 | 2017-03-22 | Scott Dorfner | Antibiotic formulations providing reduced gastrointestinal side effects and clostridium difficile infection relapse, and related methods |
CN102946891B (zh) | 2009-11-11 | 2017-09-01 | 营养健康有限公司 | 益生菌双歧杆菌菌株 |
US20150104418A1 (en) | 2014-12-18 | 2015-04-16 | Microbios, Inc. | Bacterial composition |
FR2955774A1 (fr) | 2010-02-02 | 2011-08-05 | Aragan | Preparation destinee a traiter l'exces ponderal et les desordres associes et applications de ladite preparation |
NL2004200C2 (en) | 2010-02-05 | 2011-08-08 | Friesland Brands Bv | Use of sialyl oligosaccharides in weight management. |
NL2004201C2 (en) | 2010-02-05 | 2011-08-08 | Friesland Brands Bv | Use of sialyl oligosaccharides to modulate the immune system. |
IT1398553B1 (it) | 2010-03-08 | 2013-03-01 | Probiotical Spa | Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario. |
JP5737646B2 (ja) | 2010-03-24 | 2015-06-17 | 森下仁丹株式会社 | 抗アレルギー剤 |
EP2552464B1 (en) | 2010-03-30 | 2018-02-28 | Assistance Publique - Hôpitaux de Paris | Use of bifidobacteria for preventing allergy in breastfed infants |
WO2011149335A1 (en) | 2010-05-25 | 2011-12-01 | N.V. Nutricia | Immune imprinting nutritional composition |
CA2836413A1 (en) | 2010-06-01 | 2011-12-08 | Moore Research Enterprises Llc | Cellular constituents from bacteroides, compositions thereof, and therapeutic methods employing bacteroides or cellular constituents thereof |
WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性t細胞の増殖または集積を誘導する作用を有する組成物 |
TWI417054B (zh) | 2010-06-15 | 2013-12-01 | Jen Shine Biotechnology Co Ltd | 新穎糞腸球菌ljs-01及其益生用途 |
EP2397145A1 (en) | 2010-06-18 | 2011-12-21 | Nestec S.A. | L. johnsonii La1, B. longum NCC2705 and immune disorders |
FR2962045B1 (fr) | 2010-07-05 | 2012-08-17 | Bifinove | Complexe macromoleculaire d'origine bacterienne et utilisation dudit complexe moleculaire pour prevenir et traiter les rhumatismes inflammatoires |
TWI401086B (zh) | 2010-07-20 | 2013-07-11 | Univ China Medical | 胚芽乳酸桿菌及其用途 |
US9386793B2 (en) | 2010-08-20 | 2016-07-12 | New York University | Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota |
KR101250463B1 (ko) | 2010-10-12 | 2013-04-15 | 대한민국 | 신생아 분변에서 분리한 내산소성 비피도박테리움 롱검 비피더스 유산균 및 이를 이용한 프로바이오틱 조성물 |
CN102031235B (zh) | 2010-11-09 | 2012-07-25 | 中国农业大学 | 一种粪肠球菌anse228及其应用 |
EP2455092A1 (en) | 2010-11-11 | 2012-05-23 | Nestec S.A. | Non-replicating probiotic micro-organisms protect against upper respiratory tract infections |
US20120128644A1 (en) | 2010-11-24 | 2012-05-24 | Oragenics, Inc. | Use of Bacteria to Treat and Prevent Respiratory Infections |
CN102093967B (zh) | 2010-12-02 | 2013-01-30 | 中国农业科学院特产研究所 | 一株水貂源屎肠球菌及其应用 |
ES2389547B1 (es) | 2010-12-07 | 2013-08-08 | Consejo Superior De Investigaciones Científicas (Csic) | Bifidobacterium cect 7765 y su uso en la prevención y/o tratamiento del sobrepeso, la obesidad y patologías asociadas. |
MX361355B (es) | 2011-01-10 | 2018-12-04 | Cleveland Biolabs Inc | Uso del agonista del receptor tipo toll para el tratamiento del cáncer. |
EP2481299B1 (en) | 2011-01-31 | 2016-12-07 | Dr. Fischer Gesundheitsprodukte GmbH | Bifidobacterium bifidum strains for application in gastrointestinal diseases |
JP5840368B2 (ja) | 2011-02-02 | 2016-01-06 | カルピス株式会社 | 関節炎予防改善用物質 |
WO2012108830A1 (en) | 2011-02-09 | 2012-08-16 | Lavivo Ab | Synbiotic compositions for restoration and reconstitution of gut microbiota |
BRPI1100857A2 (pt) | 2011-03-18 | 2013-05-21 | Alexandre Eduardo Nowill | agente imunomodulador e suas combinaÇÕes, seu uso e mÉtodo imunoterÁpico para a recontextualizaÇço, reprogramaÇço e reconduÇço do sistema imune em tempo real |
WO2012140636A1 (en) | 2011-04-11 | 2012-10-18 | Alimentary Health Limited | A probiotic formulation |
WO2012142605A1 (en) | 2011-04-15 | 2012-10-18 | Samaritan Health Services | Rapid recolonization deployment agent |
SG194542A1 (en) | 2011-04-20 | 2013-12-30 | Mico Bio Inc | Composition and method for enhancing an immune response |
US9567361B2 (en) | 2011-05-13 | 2017-02-14 | Glycosyn LLC | Use of purified 2′-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics |
KR20120133133A (ko) | 2011-05-30 | 2012-12-10 | 한국 한의학 연구원 | 생약 추출물 또는 이의 유산균 발효물을 포함하는 호흡기 질환의 예방 또는 치료용 조성물 |
GB201110095D0 (en) | 2011-06-15 | 2011-07-27 | Danisco | Method of treatment |
JP2013005759A (ja) | 2011-06-24 | 2013-01-10 | Kyodo Milk Industry Co Ltd | マウス腸内菌叢の推測方法 |
WO2013005836A1 (ja) | 2011-07-07 | 2013-01-10 | 長岡香料株式会社 | フルクトース吸収阻害剤 |
GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
US20130022575A1 (en) | 2011-07-19 | 2013-01-24 | Microbial Rx | Systems and methods of replacing intestinal flora |
CN102304483A (zh) | 2011-08-12 | 2012-01-04 | 北京金泰得生物科技股份有限公司 | 一株饲用屎肠球菌及其应用 |
KR101261872B1 (ko) | 2011-08-23 | 2013-05-14 | 대한민국 (식품의약품안전처장) | 장내 미생물 효소복합체 및 이의 제조방법 |
US20140363397A1 (en) | 2011-09-14 | 2014-12-11 | Queen's University At Kingston | Method for treatment of disorders of the gastrointestinal system |
GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
WO2013053836A1 (en) | 2011-10-11 | 2013-04-18 | Quantum Pharmaceuticals Sa | Composition comprising anaerobically cultivated human intestinal microbiota |
CN103082292B (zh) | 2011-11-02 | 2015-03-04 | 深圳华大基因研究院 | 罗斯氏菌(Roseburia)在治疗和预防肥胖相关疾病中的应用 |
CN102373172B (zh) | 2011-11-03 | 2013-03-20 | 北京龙科方舟生物工程技术有限公司 | 一株屎肠球菌及其应用 |
CN108676774B (zh) * | 2011-12-01 | 2023-05-09 | 国立大学法人东京大学 | 诱导调节性t细胞的增殖或积累的人源细菌 |
ES2408279B1 (es) | 2011-12-15 | 2014-09-09 | Universidad De Las Palmas De Gran Canaria | Bacteria acido láctica probiótica |
ITBG20120010A1 (it) | 2012-02-24 | 2013-08-25 | Milano Politecnico | Dispositivo per l'addestramento chirurgico |
ITMI20120471A1 (it) | 2012-03-26 | 2013-09-27 | Giovanni Mogna | Composizione a base di ceppi di batteri bifidobacterium longum in grado di aiutare il prolungamento della vita |
JP5792105B2 (ja) | 2012-03-27 | 2015-10-07 | 森永乳業株式会社 | ラクト−n−ビオースiの製造方法 |
JP6201982B2 (ja) | 2012-03-30 | 2017-09-27 | 味の素株式会社 | 糖尿病誘起細菌 |
US20130280724A1 (en) | 2012-04-11 | 2013-10-24 | Nestec Sa | Methods for diagnosing impending diarrhea |
CN104507483A (zh) | 2012-04-13 | 2015-04-08 | 波士顿学院理事会 | 益生元组合物及使用方法 |
GB201206599D0 (en) | 2012-04-13 | 2012-05-30 | Univ Manchester | Probiotic bacteria |
WO2013181694A1 (en) | 2012-06-04 | 2013-12-12 | Gaurav Agrawal | Compositions and methods for treating crohn's disease and related conditions and infections |
US9676847B2 (en) | 2012-06-25 | 2017-06-13 | Orega Biotech | IL-17 antagonist antibodies |
BR112015001884B1 (pt) | 2012-07-31 | 2020-12-01 | Société des Produits Nestlé S.A. | composição nutricional para promover a saúde musculoesquelética em pacientes com doença inflamatória intestinal (ibd), seu uso, e formulação farmacêutica, formulação nutricional, formulação de alimentação por tubo, suplemento alimentar, alimento funcional ou produto de bebida |
WO2014036182A2 (en) | 2012-08-29 | 2014-03-06 | California Institute Of Technology | Diagnosis and treatment of autism spectrum disorder |
JP2015531770A (ja) | 2012-08-29 | 2015-11-05 | サリックス ファーマシューティカルズ,インコーポレイテッド | 緩下剤組成物、ならびに便秘および関連胃腸疾患および症状を処置するための方法 |
EP2894985A4 (en) | 2012-09-13 | 2016-09-28 | Massachusetts Inst Technology | PROGRAMMABLE ACTIVE COMPOUND PROFILES OF TUMORED BACTERIA |
KR101473058B1 (ko) | 2012-09-19 | 2014-12-16 | 주식회사 쎌바이오텍 | 과민성 대장 증후군 예방 또는 치료용 조성물 |
CN103652322B (zh) | 2012-09-21 | 2016-02-10 | 临沂思科生物科技有限公司 | 一种含乳酸菌的复合益生菌饲料添加剂的制备方法 |
FR2997091B1 (fr) | 2012-10-22 | 2016-05-06 | Fond Mediterranee Infection | Utilisation d'un compose antioxydant pour la culture de bacteries sensibles a la tension en oxygene |
WO2014067976A1 (en) | 2012-10-30 | 2014-05-08 | Nestec S.A. | Compositions comprising microparticles and probiotics to deliver a synergistic immune effect |
US9839657B2 (en) | 2012-10-30 | 2017-12-12 | Deerland Enzymes, Inc. | Prebiotic compositions comprising one or more types of bacteriophage |
WO2014075745A1 (en) | 2012-11-19 | 2014-05-22 | Université Catholique de Louvain | Use of akkermansia for treating metabolic disorders |
KR102617655B1 (ko) | 2012-11-23 | 2023-12-27 | 세레스 테라퓨틱스, 인코포레이티드 | 상승작용적 박테리아 조성물, 그리고 이의 제조 방법 및 용도 |
US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
JP2016501852A (ja) | 2012-11-26 | 2016-01-21 | トーマス・ジュリアス・ボロディ | 糞便微生物叢の回復のための組成物、ならびにそれらを作製および使用する方法 |
US20140193464A1 (en) | 2013-01-08 | 2014-07-10 | Imagilin Technology, Llc | Effects of probiotics on humans and animals under environmental or biological changes |
EP2951283A4 (en) | 2013-02-04 | 2017-01-25 | Seres Therapeutics, Inc. | Compositions and methods |
KR20230110367A (ko) | 2013-02-04 | 2023-07-21 | 세레스 테라퓨틱스, 인코포레이티드 | 조성물 및 방법 |
EP3536328B1 (en) | 2013-02-22 | 2021-10-27 | The Regents of The University of California | Food or beverage product, or probiotic composition, comprising lactobacillus johnsonii 456 |
CN105228635A (zh) | 2013-03-05 | 2016-01-06 | 格罗宁根大学 | Faecalibacterium prausnitzii HTF-F(DSM 26943)在抑制炎症中的应用 |
NZ711298A (en) | 2013-03-14 | 2021-07-30 | Therabiome Llc | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
WO2014153194A2 (en) | 2013-03-14 | 2014-09-25 | Seres Health, Inc. | Methods for pathogen detection and enrichment from materials and compositions |
WO2014145970A1 (en) | 2013-03-15 | 2014-09-18 | President And Fellows Of Harvard College | Modulation of regulatory t cells via g-coupled protein receptor 43 |
EP2967077A4 (en) | 2013-03-15 | 2016-09-14 | Seres Therapeutics Inc | MICROBIAL COMPOSITIONS AND ASSOCIATED METHODS BASED ON A NETWORK |
US9669059B2 (en) | 2013-03-15 | 2017-06-06 | University Of Florida Research Foundation, Incorporated | Butyrogenic bacteria as probiotics to treat clostridium difficile |
CN103142656A (zh) | 2013-03-18 | 2013-06-12 | 广州知光生物科技有限公司 | 脆弱拟杆菌在制备防治结肠癌组合物中的应用 |
CN103156888A (zh) | 2013-03-18 | 2013-06-19 | 广州知光生物科技有限公司 | 脆弱拟杆菌在制备治疗炎症性肠病组合物中的应用 |
CN103146620A (zh) | 2013-03-25 | 2013-06-12 | 广州知光生物科技有限公司 | 具有益生菌特性的脆弱拟杆菌 |
JP2014196260A (ja) | 2013-03-29 | 2014-10-16 | 公立大学法人奈良県立医科大学 | 慢性閉塞性肺疾患の予防又は治療用組成物 |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
JP2016521284A (ja) | 2013-05-10 | 2016-07-21 | カリフォルニア インスティチュート オブ テクノロジー | 大腸ガンのプロバイオティクスによる防止および処置 |
JP6330032B2 (ja) | 2013-06-05 | 2018-05-23 | レビオティクス インコーポレイテッドRebiotix,Inc. | 微生物叢回復療法組成物を製造、処理、および梱包するための方法 |
US9511099B2 (en) | 2013-06-05 | 2016-12-06 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
WO2014201037A2 (en) | 2013-06-10 | 2014-12-18 | New York University | Methods for manipulating immune responses by altering microbiota |
WO2014200334A1 (en) | 2013-06-14 | 2014-12-18 | N.V. Nutricia | Synbiotic composition for treatment of infections in allergic patients |
WO2015003001A1 (en) | 2013-07-01 | 2015-01-08 | The Washington University | Methods for identifying supplements that increase gut colonization by an isolated bacterial species, and compositions derived therefrom |
WO2015003305A1 (zh) | 2013-07-08 | 2015-01-15 | 吉瑞高新科技股份有限公司 | 电子烟盒 |
WO2015006355A2 (en) | 2013-07-09 | 2015-01-15 | Puretech Ventures, Llc | Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease |
US10633714B2 (en) | 2013-07-21 | 2020-04-28 | Pendulum Therapeutics, Inc. | Methods and systems for microbiome characterization, monitoring and treatment |
WO2015017625A1 (en) | 2013-07-31 | 2015-02-05 | Wikifoods, Inc. | Encapsulated functional food compositions |
EP3033091B1 (en) | 2013-08-16 | 2022-09-07 | Versitech Limited | Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma |
CN103509741B (zh) | 2013-08-22 | 2015-02-18 | 河北农业大学 | 布劳特菌auh-jld56及其在牛蒡苷元转化中的应用 |
US10203329B2 (en) | 2013-09-12 | 2019-02-12 | The Johns Hopkins University | Biofilm formation to define risk for colon cancer |
PL3071052T3 (pl) | 2013-10-18 | 2020-07-27 | Innovachildfood Ab | Zbilansowany pod względem odżywczym złożony posiłek dla niemowląt i małych dzieci oraz sposób otrzymywania wspomnianego posiłku |
PL229020B1 (pl) | 2013-11-13 | 2018-05-30 | Inst Biotechnologii Surowic I Szczepionek Biomed Spolka Akcyjna | Nowy szczep Bifidobacterium breve |
US10258655B2 (en) | 2013-11-25 | 2019-04-16 | Seres Therapeutics, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
WO2015095241A2 (en) * | 2013-12-16 | 2015-06-25 | Seres Health, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
CN103981117B (zh) | 2013-12-24 | 2018-10-26 | 北京大伟嘉生物技术股份有限公司 | 一株高抗逆性屎肠球菌及其培养方法和应用 |
CN103981115B (zh) | 2013-12-24 | 2018-10-26 | 北京大伟嘉生物技术股份有限公司 | 一株高抗逆性屎肠球菌及其应用 |
CN103820363B (zh) | 2014-01-27 | 2016-02-24 | 福建省农业科学院生物技术研究所 | 一种屎肠球菌菌粉的制备与应用 |
CN103865846B (zh) | 2014-02-27 | 2016-03-30 | 扬州绿保生物科技有限公司 | 一种屎肠球菌及其制备方法 |
CN103849590B (zh) | 2014-03-25 | 2016-07-06 | 上海交通大学 | 一株耐酸短双歧杆菌BB8dpH及其应用 |
KR101683474B1 (ko) | 2014-03-26 | 2016-12-08 | 주식회사 쎌바이오텍 | 과민성 대장 증후군 예방 또는 치료용 조성물 |
US9783858B2 (en) | 2014-04-02 | 2017-10-10 | Northwestern University | Altered microbiome of chronic pelvic pain |
KR101583546B1 (ko) | 2014-04-09 | 2016-01-11 | 국립암센터 | 유전자 다형성을 이용한 소라페닙 치료에 대한 반응성 예측방법 |
CN106659746A (zh) * | 2014-04-10 | 2017-05-10 | 国立研究开发法人理化学研究所 | 用于诱导th17细胞的组合物及方法 |
CN104195075B (zh) | 2014-08-14 | 2017-04-19 | 生合生物科技股份有限公司 | 一种屎肠球菌ef08及包含它的饲料添加物和饲料 |
WO2015168534A1 (en) | 2014-05-02 | 2015-11-05 | Novogy, Inc. | Therapeutic treatment of gastrointestinal microbial imbalances through competitive microbe displacement |
SG11201608835VA (en) | 2014-05-08 | 2016-11-29 | Panoptes Pharma Ges M B H | Compounds for treating ophthalmic diseases and disorders |
CN106687130B (zh) | 2014-08-05 | 2020-01-21 | 深圳华大基因科技有限公司 | 真杆菌属在预防和治疗结直肠癌相关疾病中的用途 |
WO2016033439A2 (en) | 2014-08-28 | 2016-03-03 | Yale University | Compositions and methods for the treating an inflammatory disease or disorder |
US20160058808A1 (en) | 2014-09-03 | 2016-03-03 | California Institute Of Technology | Microbe-based modulation of serotonin biosynthesis |
CN104546934B (zh) | 2014-09-30 | 2019-04-09 | 深圳华大基因科技有限公司 | 粪副拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
CN104546933A (zh) | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 粪拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
CN104546932A (zh) | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 卵形拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
CN104546940A (zh) | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 平常拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
CN104546942A (zh) | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 多氏拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
CN104546935A (zh) | 2014-09-30 | 2015-04-29 | 深圳华大基因科技有限公司 | 多形拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用 |
WO2016057671A1 (en) | 2014-10-07 | 2016-04-14 | University Of Virginia Patent Foundation | Compositions and methods for preventing and treating infection |
CA2965663C (en) | 2014-10-24 | 2023-04-04 | Evolve Biosystems, Inc. | Activated bifidobacteria and methods of use thereof |
JP6800846B2 (ja) | 2014-10-30 | 2020-12-16 | カリフォルニア インスティチュート オブ テクノロジー | 神経発達症群における行動の改善のための細菌含有組成物、及び細菌を使用することを含む、神経発達症群における行動の改善のための方法 |
CN107106616A (zh) | 2014-10-30 | 2017-08-29 | 加利福尼亚技术学院 | 包括改善神经发育障碍行为的细菌的组合物和方法 |
EP3881680A1 (en) | 2014-10-31 | 2021-09-22 | Pendulum Therapeutics, Inc. | Methods and compositions relating to microbial treatment |
CN104435000A (zh) | 2014-11-12 | 2015-03-25 | 江南大学 | 乳酸菌对支气管哮喘治疗中的应用 |
CN107249609A (zh) | 2014-11-25 | 2017-10-13 | 纪念斯隆-凯特琳癌症中心 | 肠道微生物群和gvhd |
MA41020A (fr) | 2014-11-25 | 2017-10-03 | Evelo Biosciences Inc | Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome |
WO2016102951A1 (en) | 2014-12-23 | 2016-06-30 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
ME02997B (me) | 2014-12-23 | 2018-10-20 | 4D Pharma Res Ltd | Soj bacteroides thetaiotaomicron i njegova upotreba u smanjenju inflamacije |
CN104560820B (zh) | 2014-12-30 | 2017-10-20 | 杭州师范大学 | 屎肠球菌kq2.6及应用 |
KR20170128247A (ko) | 2015-01-23 | 2017-11-22 | 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 | 암 예방에서 단쇄 지방산의 용도 |
CN105982919A (zh) | 2015-02-26 | 2016-10-05 | 王汉成 | 生物减速剂抗癌技术 |
WO2016139217A1 (en) | 2015-03-04 | 2016-09-09 | Ab-Biotics, S.A. | Composition comprising anaerobically cultivated human intestinal microbiota |
US20180078587A1 (en) | 2015-03-18 | 2018-03-22 | Trustees Of Tufts College | Compositions and methods for preventing colorectal cancer |
EP3270938A4 (en) | 2015-03-18 | 2018-12-19 | Whole Biome Inc. | Methods and compositions relating to microbial treatment and diagnosis of skin disorders |
JP2018521013A (ja) | 2015-06-01 | 2018-08-02 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 共生微生物叢の操作による癌の処置 |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
MD3307288T2 (ro) | 2015-06-15 | 2019-12-31 | 4D Pharma Res Ltd | Compoziții care conțin tulpini bacteriene |
PL3206700T3 (pl) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Kompozycje zawierające szczepy bakteryjne |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
CN115364122A (zh) | 2015-06-15 | 2022-11-22 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
CA2990618A1 (en) | 2015-06-22 | 2016-12-29 | Esen SEFIK | Induction of lamina propria regulatory t cells |
CN105112333A (zh) | 2015-08-31 | 2015-12-02 | 江南大学 | 一种具有良好肠道定殖能力的长双歧杆菌及筛选方法和应用 |
EA034677B1 (ru) | 2015-11-20 | 2020-03-05 | 4Д Фарма Рисёрч Лимитед | Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum |
GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) * | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
WO2017091753A1 (en) | 2015-11-25 | 2017-06-01 | Memorial Sloan-Kettering Cancer Center | Methods and compositions for reducing vancomycin-resistant enterococci infection or colonization |
DK3313423T3 (da) | 2016-03-04 | 2019-05-20 | 4D Pharma Plc | Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet |
TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
WO2018112363A1 (en) | 2016-12-16 | 2018-06-21 | Evelo Biosciences, Inc. | Methods of treating cancer using parabacteroides |
WO2018112365A2 (en) | 2016-12-16 | 2018-06-21 | Evelo Biosciences, Inc. | Methods of treating colorectal cancer and melanoma using parabacteroides goldsteinii |
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2015
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2022
- 2022-08-18 JP JP2022130603A patent/JP2022169660A/ja active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2023068857A1 (ko) * | 2021-10-20 | 2023-04-27 | 주식회사 고바이오랩 | 항암 활성을 갖는 신규 박테리아 균주 및 이를 이용한 암의 완화, 예방 또는 치료용 조성물 |
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