KR20160092991A - Irak 억제제 및 이의 용도 - Google Patents

Irak 억제제 및 이의 용도 Download PDF

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Publication number
KR20160092991A
KR20160092991A KR1020167011026A KR20167011026A KR20160092991A KR 20160092991 A KR20160092991 A KR 20160092991A KR 1020167011026 A KR1020167011026 A KR 1020167011026A KR 20167011026 A KR20167011026 A KR 20167011026A KR 20160092991 A KR20160092991 A KR 20160092991A
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South Korea
Prior art keywords
disease
compound
compounds
ring
irak
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Korean (ko)
Inventor
도나 엘. 로메로
크레이그 이. 매세이
쇼네시 로빈슨
제레미 로버트 그린우드
제럴딘 해리먼
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님버스 아이리스 인코포레이티드
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Publication of KR20160092991A publication Critical patent/KR20160092991A/ko
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
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  • Orthopedic Medicine & Surgery (AREA)
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  • Urology & Nephrology (AREA)
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KR1020167011026A 2013-09-27 2014-09-25 Irak 억제제 및 이의 용도 Withdrawn KR20160092991A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361883497P 2013-09-27 2013-09-27
US61/883,497 2013-09-27
PCT/US2014/057444 WO2015048281A1 (en) 2013-09-27 2014-09-25 Irak inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
KR20160092991A true KR20160092991A (ko) 2016-08-05

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KR1020167011026A Withdrawn KR20160092991A (ko) 2013-09-27 2014-09-25 Irak 억제제 및 이의 용도

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US (2) US9518065B2 (enExample)
EP (1) EP3049086A4 (enExample)
JP (1) JP2016531870A (enExample)
KR (1) KR20160092991A (enExample)
CN (1) CN106232122A (enExample)
BR (1) BR112016006319A2 (enExample)
CA (1) CA2925211A1 (enExample)
MX (1) MX2016003843A (enExample)
RU (1) RU2016110852A (enExample)
TW (1) TW201522349A (enExample)
WO (1) WO2015048281A1 (enExample)

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WO2017004133A1 (en) * 2015-06-29 2017-01-05 Nimbus Iris, Inc. Irak inhibitors and uses thereof
DK3331877T3 (da) * 2015-08-04 2022-01-03 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Pyrazolpyrimidinderivat og anvendelser deraf
CA2993661A1 (en) 2015-08-04 2017-02-09 Rigel Pharmaceuticals, Inc. Benzazole compounds and methods for making and using the compounds
KR102110573B1 (ko) * 2015-08-13 2020-05-13 베이징 한미 파마슈티컬 컴퍼니 리미티드 Irak4억제제 및 이의 용도
KR102048719B1 (ko) * 2015-08-13 2019-11-26 베이징 한미 파마슈티컬 컴퍼니 리미티드 Irak4억제제 및 이의 용도
GB201518456D0 (en) * 2015-10-19 2015-12-02 Galapagos Nv Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory, autoimmune and/or proliferative diseases
SG10201508795XA (en) * 2015-10-23 2017-05-30 Agency Science Tech & Res Method for treating cancer
WO2017205762A1 (en) * 2016-05-27 2017-11-30 Pharmacyclics Llc Inhibitors of interleukin-1 receptor-associated kinase
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