KR20160067195A - 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 - Google Patents
피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 Download PDFInfo
- Publication number
- KR20160067195A KR20160067195A KR1020167014302A KR20167014302A KR20160067195A KR 20160067195 A KR20160067195 A KR 20160067195A KR 1020167014302 A KR1020167014302 A KR 1020167014302A KR 20167014302 A KR20167014302 A KR 20167014302A KR 20160067195 A KR20160067195 A KR 20160067195A
- Authority
- KR
- South Korea
- Prior art keywords
- salt
- nicotinamide riboside
- skin
- sodium
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/048—Pyridine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020217026414A KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361897713P | 2013-10-30 | 2013-10-30 | |
| US61/897,713 | 2013-10-30 | ||
| PCT/US2014/063260 WO2015066382A1 (en) | 2013-10-30 | 2014-10-30 | Nicotinamide riboside compositions for topical use in treating skin conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217026414A Division KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160067195A true KR20160067195A (ko) | 2016-06-13 |
Family
ID=53005146
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217026414A Ceased KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| KR1020167014302A Ceased KR20160067195A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| KR1020227022241A Ceased KR20220098049A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217026414A Ceased KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227022241A Ceased KR20220098049A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10688118B2 (enExample) |
| EP (1) | EP3063163B1 (enExample) |
| JP (1) | JP6509844B2 (enExample) |
| KR (3) | KR20210107895A (enExample) |
| CN (2) | CN109985056A (enExample) |
| AU (1) | AU2014342185B2 (enExample) |
| CA (1) | CA2928656C (enExample) |
| ES (1) | ES2925879T3 (enExample) |
| MX (2) | MX394291B (enExample) |
| NZ (1) | NZ719328A (enExample) |
| WO (1) | WO2015066382A1 (enExample) |
| ZA (1) | ZA201603314B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020122547A1 (ko) * | 2018-12-14 | 2020-06-18 | 주식회사 휴메딕스 | 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20210077156A (ko) | 2019-12-17 | 2021-06-25 | 주식회사 휴메딕스 | 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20240000152A (ko) * | 2022-06-23 | 2024-01-02 | 제너럴바이오(주) | Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물 |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2016015997A (es) * | 2014-06-02 | 2017-04-05 | Glaxosmithkline Intellectual Property (No 2) Ltd | Preparacion y uso de beta-d-nicotinamida ribosido cristalina. |
| US10485814B2 (en) | 2014-06-06 | 2019-11-26 | Glaxosmithkline Intellectual Property (No. 2) Limited | Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof |
| CA2956163C (en) | 2014-07-24 | 2023-01-10 | W.R. Grace & Co.-Conn. | Crystalline form of nicotinamide riboside |
| CN107428791B (zh) | 2015-03-09 | 2024-05-28 | 格雷斯公司 | 烟酰胺核苷的结晶形式 |
| KR102426320B1 (ko) | 2015-03-16 | 2022-07-29 | 크로마덱스 아이엔씨. | 니코틴산 리보사이드 또는 니코틴아미드 리보사이드 조성물, 이의 환원 유도체, 및 이의 용도 |
| US20160317420A1 (en) | 2015-05-01 | 2016-11-03 | The Procter & Gamble Company | Method of improving the appearance of skin and compositions therefor |
| WO2016178949A1 (en) * | 2015-05-01 | 2016-11-10 | The Procter & Gamble Company | Method of improving skin health and compositions therefor |
| EP3288529A1 (en) | 2015-05-01 | 2018-03-07 | The Procter and Gamble Company | Method of improving the appearance of skin and compositions therefor using nicotinamide riboside |
| CA2989115C (en) * | 2015-06-10 | 2024-01-02 | Elysium Health, Inc. | Nicotinamide riboside and pterostilbene compositions and methods for treatment of skin disorders |
| WO2016210232A1 (en) * | 2015-06-25 | 2016-12-29 | N.V. Perricone Llc | Niacinamide mononucleotide formulations for skin aging |
| US20160374918A1 (en) * | 2015-06-29 | 2016-12-29 | The Procter & Gamble Company | Encapsulated skin care agent |
| US20160374908A1 (en) | 2015-06-29 | 2016-12-29 | The Procter & Gamble Company | Skin care composition and methods of using the same |
| US11013678B2 (en) | 2015-06-29 | 2021-05-25 | The Procter & Gamble Company | Multi-component skin care product |
| US9833398B2 (en) | 2016-01-11 | 2017-12-05 | The Procter & Gamble Company | Method of treating a skin condition and compositions therefor |
| CA3017254C (en) | 2016-03-16 | 2023-08-22 | ChromaDex Inc. | B-vitamin and amino acid conjugates of nicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof |
| US10183036B2 (en) | 2016-04-20 | 2019-01-22 | ChromaDex Inc. | Use of nicotinic acid riboside or nicotinamide riboside derivatives, and reduced derivatives thereof, as NAD+ increasing precursors |
| WO2018039207A1 (en) | 2016-08-22 | 2018-03-01 | Elysium Health, Inc. | Nicotinamide riboside and pterostilbene compositions and methods for treatment of neurodegenerative disorders |
| CN120383644A (zh) | 2016-11-11 | 2025-07-29 | 英国贝尔法斯特女王大学 | 烟酰基核苷和还原的烟酰基核苷、其改性衍生物、磷酸化的类似物、腺苷二核苷酸共轭物、以及新颖结晶形式的有效且可规模化的合成 |
| AU2017367092B2 (en) | 2016-11-29 | 2022-11-03 | University Of Iowa Research Foundation | Use of NAD precursors for improving maternal health and/or offspring health |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| CA3047495A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Topical skin lightening additive and composition with amino acids and nicotinamide compounds |
| US11337908B2 (en) | 2016-12-21 | 2022-05-24 | Conopco, Inc. | Personal care compositions with cystine |
| US11260005B2 (en) | 2016-12-21 | 2022-03-01 | Conopco, Inc. | Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids |
| WO2018114745A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Personal care compositions comprising poorly soluble compounds |
| RU2651047C1 (ru) * | 2017-05-04 | 2018-04-18 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Лекарственная композиция цитопротекторного действия и способ ее получения |
| US20200085849A1 (en) * | 2017-05-18 | 2020-03-19 | Elysium Health, Inc. | Methods and compositions for improving sleep |
| EP3642214A2 (en) | 2017-06-19 | 2020-04-29 | Gangadhara Ganapati | Nicotinamide riboside derivatives and their uses |
| CN110785161B (zh) | 2017-06-23 | 2023-06-20 | 宝洁公司 | 用于改善皮肤外观的组合物和方法 |
| CA3108015A1 (en) | 2017-07-28 | 2019-01-31 | Centers For Age Control, Inc. | Compositions and methods for preventing and reversing aspects of aging |
| JP7210459B2 (ja) * | 2017-09-14 | 2023-01-23 | めぐみ 田中 | 老化防止剤及び老化防止方法 |
| GB201716391D0 (en) * | 2017-10-06 | 2017-11-22 | Xobaderm Ltd | Kit for delivery of an active compound into a biological barrier |
| CA3086535A1 (en) | 2017-12-22 | 2019-06-27 | Elysium Health, Inc. | Crystalline forms of nicotinamide riboside chloride |
| EP3817717A1 (en) | 2018-07-03 | 2021-05-12 | The Procter & Gamble Company | Method of treating a skin condition |
| CN110913864B (zh) * | 2018-08-17 | 2022-12-13 | 邦泰生物工程(深圳)有限公司 | 一种稳定型烟酰胺核糖组合物及其制备方法 |
| WO2020131578A2 (en) | 2018-12-17 | 2020-06-25 | Mitopower Llc | Nicotinyl riboside compounds and their uses |
| EP4471043A3 (en) * | 2019-07-19 | 2025-03-05 | Biosynth AG | Method of making nicotinamide ribofuranoside salts, nicotinamide ribofuranoside salts as such, and uses thereof |
| CN110638827A (zh) * | 2019-10-17 | 2020-01-03 | 泓博元生命科技(深圳)有限公司 | Nadh及其盐在制备皮肤色素抑制剂中的应用 |
| CN111166760A (zh) * | 2019-12-17 | 2020-05-19 | 浙江安赛新材料科技有限公司 | β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用 |
| CN111184732B (zh) * | 2020-03-04 | 2023-09-08 | 武汉华纳联合药业有限公司 | 一种复合组合物制剂及其制备方法和皮肤炎症中的应用 |
| CN111454311B (zh) * | 2020-04-03 | 2021-10-19 | 深圳市迪克曼科技开发有限公司 | 烟酰胺核糖的有机酸盐及其组合物与制备方法 |
| FR3110410A1 (fr) * | 2020-05-20 | 2021-11-26 | Nuvamid Sa | Compositions cosmétiques anti-âge comprenant de la NMN |
| WO2021234009A1 (fr) * | 2020-05-20 | 2021-11-25 | Nuvamid Sa | Compositions cosmetiques anti-age comprenant du nmn |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
| CN111632049A (zh) * | 2020-06-09 | 2020-09-08 | 西北农林科技大学 | 一种通过综合矫正细胞活性氧簇代谢紊乱以缓解睾丸衰老损伤的复合配方 |
| WO2022047182A1 (en) * | 2020-08-28 | 2022-03-03 | University Of Washington | High dose nicotinamide adenine dinucleotide (nad) precursor regimens for reduction of inflammation in human patients with preexisting inflammation |
| WO2022157173A1 (en) * | 2021-01-19 | 2022-07-28 | Biosynth Ag | Method of making nicotinamide ribofuranoside salts by salt metathesis, the crystalline form of its tosylate salt and the co-crystallized form of its chloride:iodide salt |
| EP4333807A1 (en) * | 2021-05-04 | 2024-03-13 | Sovida Solutions Ltd. | Nicotinamide adenine dinucleotide (nad) compositions, methods of manufacturing thereof, and methods of use thereof |
| CN114129509B (zh) * | 2021-12-03 | 2023-12-01 | 药酚享科技(北京)有限公司 | 一种保湿性nmn亲水凝胶剂及其制备方法 |
| CN116621898A (zh) * | 2022-04-13 | 2023-08-22 | 深圳市迪克曼科技开发有限公司 | 烟酰胺核糖的有机酸盐及其结晶形态、制备方法与用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100369602C (zh) * | 2001-02-22 | 2008-02-20 | 荷兰联合利华有限公司 | 改进的皮肤用组合物 |
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| CA2555675A1 (en) | 2004-02-10 | 2005-08-25 | Trustees Of Dartmouth College | Nicotinamide riboside kinase compositions and methods for using the same |
| ES2663226T3 (es) | 2004-06-04 | 2018-04-11 | Washington University | Procedimientos y composiciones para tratar neuropatías |
| CA2610854A1 (en) | 2005-03-30 | 2006-10-05 | Sirtris Pharmaceuticals, Inc. | Nicotinamide riboside and analogues thereof |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| CN101257897A (zh) * | 2005-07-07 | 2008-09-03 | 西特里斯药业公司 | 用于治疗或预防肥胖、胰岛素抵抗障碍和线粒体相关障碍的方法和相关组合物 |
| JP2009500357A (ja) * | 2005-07-07 | 2009-01-08 | サートリス ファーマシューティカルズ, インコーポレイテッド | 肥満、インスリン抵抗性障害およびミトコンドリア関連障害を処置または予防するための方法および関連する組成物 |
| ES2670927T3 (es) | 2005-11-18 | 2018-06-04 | Cornell Research Foundation, Inc. | Composiciones de nicotinoil ribósido y métodos de uso |
| WO2008110268A1 (en) * | 2007-03-12 | 2008-09-18 | Dsm Ip Assets B.V. | Cosmetic compositions |
| US20090069444A1 (en) | 2007-09-07 | 2009-03-12 | The United States Of America, As Represented By Th E Secretary Of Agriculture | Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration |
| US20130004463A1 (en) * | 2010-01-06 | 2013-01-03 | Kabushiki Kaisha Yakult Honsha | Dna damage repair promoter for oral application, and elastase activity inhibitor for oral application |
-
2014
- 2014-10-30 KR KR1020217026414A patent/KR20210107895A/ko not_active Ceased
- 2014-10-30 KR KR1020167014302A patent/KR20160067195A/ko not_active Ceased
- 2014-10-30 NZ NZ719328A patent/NZ719328A/en unknown
- 2014-10-30 US US15/033,285 patent/US10688118B2/en active Active
- 2014-10-30 JP JP2016526337A patent/JP6509844B2/ja active Active
- 2014-10-30 CN CN201910027571.7A patent/CN109985056A/zh active Pending
- 2014-10-30 CN CN201480071722.4A patent/CN105873937A/zh active Pending
- 2014-10-30 CA CA2928656A patent/CA2928656C/en active Active
- 2014-10-30 EP EP14857903.0A patent/EP3063163B1/en active Active
- 2014-10-30 KR KR1020227022241A patent/KR20220098049A/ko not_active Ceased
- 2014-10-30 MX MX2021009652A patent/MX394291B/es unknown
- 2014-10-30 MX MX2016005574A patent/MX385305B/es unknown
- 2014-10-30 ES ES14857903T patent/ES2925879T3/es active Active
- 2014-10-30 WO PCT/US2014/063260 patent/WO2015066382A1/en not_active Ceased
- 2014-10-30 AU AU2014342185A patent/AU2014342185B2/en active Active
-
2016
- 2016-05-16 ZA ZA2016/03314A patent/ZA201603314B/en unknown
-
2020
- 2020-06-03 US US16/891,824 patent/US11033568B2/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020122547A1 (ko) * | 2018-12-14 | 2020-06-18 | 주식회사 휴메딕스 | 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20210077156A (ko) | 2019-12-17 | 2021-06-25 | 주식회사 휴메딕스 | 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20240000152A (ko) * | 2022-06-23 | 2024-01-02 | 제너럴바이오(주) | Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6509844B2 (ja) | 2019-05-08 |
| ES2925879T3 (es) | 2022-10-20 |
| MX394291B (es) | 2025-03-24 |
| EP3063163A1 (en) | 2016-09-07 |
| KR20210107895A (ko) | 2021-09-01 |
| MX2016005574A (es) | 2016-12-09 |
| CN105873937A (zh) | 2016-08-17 |
| CA2928656A1 (en) | 2015-05-07 |
| JP2016538271A (ja) | 2016-12-08 |
| WO2015066382A1 (en) | 2015-05-07 |
| AU2014342185B2 (en) | 2019-01-03 |
| US10688118B2 (en) | 2020-06-23 |
| KR20220098049A (ko) | 2022-07-08 |
| ZA201603314B (en) | 2017-09-27 |
| CA2928656C (en) | 2020-07-28 |
| US11033568B2 (en) | 2021-06-15 |
| US20200289536A1 (en) | 2020-09-17 |
| MX2021009652A (es) | 2022-07-26 |
| MX385305B (es) | 2025-03-18 |
| EP3063163A4 (en) | 2017-05-10 |
| NZ719328A (en) | 2022-04-29 |
| CN109985056A (zh) | 2019-07-09 |
| EP3063163B1 (en) | 2022-08-10 |
| US20160250241A1 (en) | 2016-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11033568B2 (en) | Nicotinamide riboside compositions for topical use in treating skin conditions | |
| AU2014342185A1 (en) | Nicotinamide riboside compositions for topical use in treating skin conditions | |
| EP3288531B1 (en) | Method of improving skin health and compositions therefor | |
| BR9712648B1 (pt) | composição compreendendo pelo menos dois compostos selecionados dentre anti-radical, antinflamatório e antialérgico. | |
| US20100286271A1 (en) | Nitro-alkyl Compound Compositions | |
| US8816065B2 (en) | Pharmaceutical or cosmetic composition containing nicotinic acid adenine dinucleotide phosphate or derivative thereof | |
| US20250127700A1 (en) | Methods of treating hyperpigmentation disorders | |
| US20150202187A1 (en) | Compositions and methods for treatment of vitiligo | |
| ES2827253T3 (es) | Preparación cutánea externa antienvejecimiento | |
| Legiawati | Centella asiatica: alternative dry skin therapy in type 2 diabetes mellitus | |
| HK40011054A (en) | Nicotinamide nucleoside composition for topical use in the treatment of dermatosis | |
| BR112018011580B1 (pt) | Compostos de éster, compostos de amida, composição e uso de pelo menos um composto | |
| JP2007153863A (ja) | 毛髪改善外用剤 | |
| RU2793250C2 (ru) | Композиция и способы лечения патологических состояний кожи; использование света и гидрохлорида глюкозамина | |
| WO2023058731A1 (ja) | 皮膚外用組成物及びその利用、並びに皮膚外用組成物原料 | |
| MX2007006059A (es) | Composicion de crema desmanchadora de piel. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20160527 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20191018 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20201127 Patent event code: PE09021S01D |
|
| AMND | Amendment | ||
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20210720 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20201127 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
|
| AMND | Amendment | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20210819 |
|
| PX0901 | Re-examination |
Patent event code: PX09011S01I Patent event date: 20210720 Comment text: Decision to Refuse Application Patent event code: PX09012R01I Patent event date: 20210526 Comment text: Amendment to Specification, etc. |
|
| PX0601 | Decision of rejection after re-examination |
Comment text: Decision to Refuse Application Patent event code: PX06014S01D Patent event date: 20210923 Comment text: Amendment to Specification, etc. Patent event code: PX06012R01I Patent event date: 20210819 Comment text: Decision to Refuse Application Patent event code: PX06011S01I Patent event date: 20210720 Comment text: Amendment to Specification, etc. Patent event code: PX06012R01I Patent event date: 20210526 Comment text: Notification of reason for refusal Patent event code: PX06013S01I Patent event date: 20201127 |
|
| X601 | Decision of rejection after re-examination |