KR20160067195A - 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 - Google Patents
피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 Download PDFInfo
- Publication number
- KR20160067195A KR20160067195A KR1020167014302A KR20167014302A KR20160067195A KR 20160067195 A KR20160067195 A KR 20160067195A KR 1020167014302 A KR1020167014302 A KR 1020167014302A KR 20167014302 A KR20167014302 A KR 20167014302A KR 20160067195 A KR20160067195 A KR 20160067195A
- Authority
- KR
- South Korea
- Prior art keywords
- salt
- nicotinamide riboside
- skin
- sodium
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/048—Pyridine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020217026414A KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361897713P | 2013-10-30 | 2013-10-30 | |
| US61/897,713 | 2013-10-30 | ||
| PCT/US2014/063260 WO2015066382A1 (en) | 2013-10-30 | 2014-10-30 | Nicotinamide riboside compositions for topical use in treating skin conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217026414A Division KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160067195A true KR20160067195A (ko) | 2016-06-13 |
Family
ID=53005146
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167014302A Ceased KR20160067195A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| KR1020227022241A Ceased KR20220098049A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| KR1020217026414A Ceased KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227022241A Ceased KR20220098049A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
| KR1020217026414A Ceased KR20210107895A (ko) | 2013-10-30 | 2014-10-30 | 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10688118B2 (enExample) |
| EP (1) | EP3063163B1 (enExample) |
| JP (1) | JP6509844B2 (enExample) |
| KR (3) | KR20160067195A (enExample) |
| CN (2) | CN105873937A (enExample) |
| AU (1) | AU2014342185B2 (enExample) |
| CA (1) | CA2928656C (enExample) |
| ES (1) | ES2925879T3 (enExample) |
| MX (2) | MX385305B (enExample) |
| NZ (1) | NZ719328A (enExample) |
| WO (1) | WO2015066382A1 (enExample) |
| ZA (1) | ZA201603314B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020122547A1 (ko) * | 2018-12-14 | 2020-06-18 | 주식회사 휴메딕스 | 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20210077156A (ko) | 2019-12-17 | 2021-06-25 | 주식회사 휴메딕스 | 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20240000152A (ko) * | 2022-06-23 | 2024-01-02 | 제너럴바이오(주) | Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물 |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2016149764A (ru) * | 2014-06-02 | 2018-07-17 | Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед | Получение и применение кристаллического бета-d-никотинамида рибозида |
| EP3152220A1 (en) | 2014-06-06 | 2017-04-12 | Glaxosmithkline Intellectual Property (No. 2) Limited | Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof |
| ES2908332T3 (es) | 2014-07-24 | 2022-04-28 | Grace W R & Co | Forma cristalina de cloruro de ribosilnicotinamida |
| ES2963057T3 (es) | 2015-03-09 | 2024-03-25 | Grace W R & Co | Forma cristalina de ribósido de nicotinamida |
| KR102426320B1 (ko) * | 2015-03-16 | 2022-07-29 | 크로마덱스 아이엔씨. | 니코틴산 리보사이드 또는 니코틴아미드 리보사이드 조성물, 이의 환원 유도체, 및 이의 용도 |
| WO2016178945A1 (en) | 2015-05-01 | 2016-11-10 | The Procter & Gamble Company | Method of improving the appearance of skin and compositions therefor using nicotinamide riboside |
| US20160317418A1 (en) | 2015-05-01 | 2016-11-03 | The Procter & Gamble Company | Method of improving the appearance of skin and compositions therefor |
| WO2016178949A1 (en) * | 2015-05-01 | 2016-11-10 | The Procter & Gamble Company | Method of improving skin health and compositions therefor |
| CN107849083A (zh) | 2015-06-10 | 2018-03-27 | 益力舒健康公司 | 用于治疗皮肤病症的烟酰胺核苷和紫檀芪组合物和方法 |
| WO2016210232A1 (en) * | 2015-06-25 | 2016-12-29 | N.V. Perricone Llc | Niacinamide mononucleotide formulations for skin aging |
| WO2017004102A1 (en) | 2015-06-29 | 2017-01-05 | The Procter & Gamble Company | Multi-component skin care product comprising nicoinamide riboside in a multi-chambered container |
| WO2017004101A1 (en) | 2015-06-29 | 2017-01-05 | The Procter & Gamble Company | Skin care compositions comprising particles with nicotinamide riboside and methods of using the same |
| WO2017004100A1 (en) | 2015-06-29 | 2017-01-05 | The Procter & Gamble Company | Encapsulated particles comprising nicotinamide riboside |
| CN115414273B (zh) | 2016-01-11 | 2024-01-30 | 宝洁公司 | 处理皮肤状况的方法以及用于其的组合物 |
| CA3017254C (en) | 2016-03-16 | 2023-08-22 | ChromaDex Inc. | B-vitamin and amino acid conjugates of nicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof |
| KR20190008246A (ko) * | 2016-04-20 | 2019-01-23 | 크로마덱스 아이엔씨. | Nad+ 증가용 전구체로서 니코틴산 리보사이드 또는 니코틴아미드 리보사이트 유도체 및 이의 환원된 유도체의 용도 |
| MX2019002211A (es) * | 2016-08-22 | 2019-10-30 | Elysium Health Inc | Composiciones de nicotinamida ribosido y pterostilbeno y metodos para el tratamiento de trastornos neurodegenerativos. |
| CN120383644A (zh) | 2016-11-11 | 2025-07-29 | 英国贝尔法斯特女王大学 | 烟酰基核苷和还原的烟酰基核苷、其改性衍生物、磷酸化的类似物、腺苷二核苷酸共轭物、以及新颖结晶形式的有效且可规模化的合成 |
| JP7136795B2 (ja) | 2016-11-29 | 2022-09-13 | ユニバーシティー オブ アイオワ リサーチ ファウンデーション | 母体の健康および/または子の健康を向上させるためのnad前駆体の使用 |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| CA3046037A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids |
| WO2018114749A1 (en) | 2016-12-21 | 2018-06-28 | Unilever Plc | Personal care compositions with cystine |
| EA038885B1 (ru) | 2016-12-21 | 2021-11-02 | ЮНИЛЕВЕР АйПи ХОЛДИНГС Б.В. | Осветляющая кожу добавка для местного применения и композиция с аминокислотами и никотинамидными соединениями |
| CN110121331B (zh) | 2016-12-21 | 2022-09-16 | 联合利华知识产权控股有限公司 | 含有难溶性化合物的个人护理组合物 |
| RU2651047C1 (ru) * | 2017-05-04 | 2018-04-18 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Лекарственная композиция цитопротекторного действия и способ ее получения |
| EP3624808A4 (en) * | 2017-05-18 | 2021-03-03 | Elysium Health, Inc. | PROCEDURES AND COMPOSITIONS FOR IMPROVED SLEEP |
| US11286274B2 (en) | 2017-06-19 | 2022-03-29 | Mitopower Llc | Nicotinamide riboside derivatives and their uses |
| WO2018237218A1 (en) | 2017-06-23 | 2018-12-27 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
| WO2019023471A1 (en) * | 2017-07-28 | 2019-01-31 | Centers For Age Control, Inc. | COMPOSITIONS AND METHODS FOR PREVENTING AND INVERTING THE ASPECTS OF AGING |
| EP3682746A4 (en) * | 2017-09-14 | 2021-03-10 | Megumi Tanaka | AGING PROTECTION AGENTS AND AGING PROTECTION PROCEDURES |
| GB201716391D0 (en) * | 2017-10-06 | 2017-11-22 | Xobaderm Ltd | Kit for delivery of an active compound into a biological barrier |
| JP2021506898A (ja) | 2017-12-22 | 2021-02-22 | エリシウム ヘルス,インコーポレーテッド | ニコチンアミドリボシドクロリドの結晶形態 |
| KR20210011964A (ko) | 2018-07-03 | 2021-02-02 | 더 프록터 앤드 갬블 캄파니 | 피부 병태를 치료하는 방법 |
| JP6887025B2 (ja) * | 2018-08-17 | 2021-06-16 | 邦泰生物工程(深▲セン▼)有限公司 | 安定型ニコチンアミドリボシド組成物及びその調製方法 |
| US11833167B2 (en) | 2018-12-17 | 2023-12-05 | Mitopower Llc | Nicotinyl riboside compounds and their uses |
| CN119684381A (zh) | 2019-07-19 | 2025-03-25 | 生物合成股份公司 | 烟酰胺呋喃核糖苷盐的结晶形式以及包含其的营养补充剂和药物组合物 |
| CN110638827A (zh) * | 2019-10-17 | 2020-01-03 | 泓博元生命科技(深圳)有限公司 | Nadh及其盐在制备皮肤色素抑制剂中的应用 |
| CN111166760A (zh) * | 2019-12-17 | 2020-05-19 | 浙江安赛新材料科技有限公司 | β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用 |
| CN111184732B (zh) * | 2020-03-04 | 2023-09-08 | 武汉华纳联合药业有限公司 | 一种复合组合物制剂及其制备方法和皮肤炎症中的应用 |
| CN111454311B (zh) * | 2020-04-03 | 2021-10-19 | 深圳市迪克曼科技开发有限公司 | 烟酰胺核糖的有机酸盐及其组合物与制备方法 |
| US20230210746A1 (en) * | 2020-05-20 | 2023-07-06 | Nuvamid Sa | Anti-aging cosmetic compositions comprising nmn |
| FR3110410A1 (fr) * | 2020-05-20 | 2021-11-26 | Nuvamid Sa | Compositions cosmétiques anti-âge comprenant de la NMN |
| JP7590462B2 (ja) | 2020-06-01 | 2024-11-26 | ザ プロクター アンド ギャンブル カンパニー | ビタミンb3化合物の皮膚への浸透を改善する方法 |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
| CN111632049A (zh) * | 2020-06-09 | 2020-09-08 | 西北农林科技大学 | 一种通过综合矫正细胞活性氧簇代谢紊乱以缓解睾丸衰老损伤的复合配方 |
| US20230263817A1 (en) * | 2020-08-28 | 2023-08-24 | University Of Washington | High dose nicotinamide adenine dinucleotide (nad) precursor regimens for reduction of inflammation in human patients with preexisting inflammation |
| US20240059727A1 (en) * | 2021-01-19 | 2024-02-22 | Biosynth Ag | Method of making nicotinamide ribofuranoside salts by salt metathesis, the crystalline form of its tosylate salt and the co-crystallized form of its chloride:iodide salt |
| US20220354879A1 (en) * | 2021-05-04 | 2022-11-10 | Sovida Solutions Ltd. | Nicotinamide adenine dinucleotide (nad) compositions, methods of manufacturing thereof, and methods of use thereof |
| CN114129509B (zh) * | 2021-12-03 | 2023-12-01 | 药酚享科技(北京)有限公司 | 一种保湿性nmn亲水凝胶剂及其制备方法 |
| CN114933621A (zh) * | 2022-04-13 | 2022-08-23 | 深圳市迪克曼生物科技有限公司 | 烟酰胺核糖的有机酸盐及其结晶形态、制备方法与用途 |
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| WO2002067889A2 (en) * | 2001-02-22 | 2002-09-06 | Unilever Plc | Skin composition for reducing skin oils and grease |
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| AU2005211773B2 (en) | 2004-02-10 | 2009-06-25 | Trustees Of Dartmouth College | Nicotinamide riboside kinase compositions and methods for using the same |
| DK1755391T3 (en) | 2004-06-04 | 2016-02-08 | Univ Washington | METHODS AND COMPOSITIONS FOR THE TREATMENT OF neuropathies |
| CA2610854A1 (en) | 2005-03-30 | 2006-10-05 | Sirtris Pharmaceuticals, Inc. | Nicotinamide riboside and analogues thereof |
| WO2006138418A2 (en) | 2005-06-14 | 2006-12-28 | President And Fellows Of Harvard College | Improvement of cognitive performance with sirtuin activators |
| WO2007008548A2 (en) * | 2005-07-07 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| CN101257897A (zh) * | 2005-07-07 | 2008-09-03 | 西特里斯药业公司 | 用于治疗或预防肥胖、胰岛素抵抗障碍和线粒体相关障碍的方法和相关组合物 |
| WO2007061798A2 (en) | 2005-11-18 | 2007-05-31 | Cornell Research Foundation, Inc. | Nicotinoyl riboside compositions and methods of use |
| ES2439582T3 (es) * | 2007-03-12 | 2014-01-23 | Dsm Ip Assets B.V. | Composiciones cosméticas |
| US20090069444A1 (en) | 2007-09-07 | 2009-03-12 | The United States Of America, As Represented By Th E Secretary Of Agriculture | Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration |
| MX2012007873A (es) * | 2010-01-06 | 2012-07-25 | Yakult Honsha Kk | Promotor de reparacion del daño de acido desoxirribonucleico para aplicacion oral e inhibidor de la actividad de elastasa para apalicacion oral. |
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2014
- 2014-10-30 CN CN201480071722.4A patent/CN105873937A/zh active Pending
- 2014-10-30 JP JP2016526337A patent/JP6509844B2/ja active Active
- 2014-10-30 KR KR1020167014302A patent/KR20160067195A/ko not_active Ceased
- 2014-10-30 NZ NZ719328A patent/NZ719328A/en unknown
- 2014-10-30 AU AU2014342185A patent/AU2014342185B2/en active Active
- 2014-10-30 KR KR1020227022241A patent/KR20220098049A/ko not_active Ceased
- 2014-10-30 MX MX2016005574A patent/MX385305B/es unknown
- 2014-10-30 CA CA2928656A patent/CA2928656C/en active Active
- 2014-10-30 KR KR1020217026414A patent/KR20210107895A/ko not_active Ceased
- 2014-10-30 ES ES14857903T patent/ES2925879T3/es active Active
- 2014-10-30 WO PCT/US2014/063260 patent/WO2015066382A1/en not_active Ceased
- 2014-10-30 MX MX2021009652A patent/MX394291B/es unknown
- 2014-10-30 CN CN201910027571.7A patent/CN109985056A/zh active Pending
- 2014-10-30 EP EP14857903.0A patent/EP3063163B1/en active Active
- 2014-10-30 US US15/033,285 patent/US10688118B2/en active Active
-
2016
- 2016-05-16 ZA ZA2016/03314A patent/ZA201603314B/en unknown
-
2020
- 2020-06-03 US US16/891,824 patent/US11033568B2/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020122547A1 (ko) * | 2018-12-14 | 2020-06-18 | 주식회사 휴메딕스 | 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20210077156A (ko) | 2019-12-17 | 2021-06-25 | 주식회사 휴메딕스 | 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체 |
| KR20240000152A (ko) * | 2022-06-23 | 2024-01-02 | 제너럴바이오(주) | Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물 |
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|---|---|
| MX2021009652A (es) | 2022-07-26 |
| ZA201603314B (en) | 2017-09-27 |
| WO2015066382A1 (en) | 2015-05-07 |
| US11033568B2 (en) | 2021-06-15 |
| US10688118B2 (en) | 2020-06-23 |
| AU2014342185B2 (en) | 2019-01-03 |
| KR20220098049A (ko) | 2022-07-08 |
| JP6509844B2 (ja) | 2019-05-08 |
| ES2925879T3 (es) | 2022-10-20 |
| CA2928656A1 (en) | 2015-05-07 |
| MX2016005574A (es) | 2016-12-09 |
| NZ719328A (en) | 2022-04-29 |
| CA2928656C (en) | 2020-07-28 |
| CN105873937A (zh) | 2016-08-17 |
| EP3063163A4 (en) | 2017-05-10 |
| MX385305B (es) | 2025-03-18 |
| US20200289536A1 (en) | 2020-09-17 |
| EP3063163A1 (en) | 2016-09-07 |
| CN109985056A (zh) | 2019-07-09 |
| JP2016538271A (ja) | 2016-12-08 |
| EP3063163B1 (en) | 2022-08-10 |
| MX394291B (es) | 2025-03-24 |
| KR20210107895A (ko) | 2021-09-01 |
| US20160250241A1 (en) | 2016-09-01 |
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