KR20150023670A - 조건적 녹아웃 대립유전자의 생성 방법 및 이를 위한 조성물 - Google Patents

조건적 녹아웃 대립유전자의 생성 방법 및 이를 위한 조성물 Download PDF

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KR20150023670A
KR20150023670A KR1020157000353A KR20157000353A KR20150023670A KR 20150023670 A KR20150023670 A KR 20150023670A KR 1020157000353 A KR1020157000353 A KR 1020157000353A KR 20157000353 A KR20157000353 A KR 20157000353A KR 20150023670 A KR20150023670 A KR 20150023670A
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소렌 워밍
케이트 알. 앤더슨
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제넨테크, 인크.
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    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
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    • A01K67/0276Knock-out vertebrates
    • AHUMAN NECESSITIES
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    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
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KR1020157000353A 2012-06-12 2013-06-12 조건적 녹아웃 대립유전자의 생성 방법 및 이를 위한 조성물 Withdrawn KR20150023670A (ko)

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US201261658670P 2012-06-12 2012-06-12
US61/658,670 2012-06-12
PCT/US2013/045382 WO2013188522A2 (en) 2012-06-12 2013-06-12 Methods and compositions for generating conditional knock-out alleles

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KR20150023670A true KR20150023670A (ko) 2015-03-05

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US (1) US20150128300A1 (enExample)
EP (1) EP2858486A4 (enExample)
JP (1) JP6279562B2 (enExample)
KR (1) KR20150023670A (enExample)
CN (1) CN104540382A (enExample)
BR (1) BR112014031080A2 (enExample)
CA (1) CA2876076A1 (enExample)
HK (1) HK1209276A1 (enExample)
MX (1) MX2014015204A (enExample)
RU (1) RU2014153918A (enExample)
WO (1) WO2013188522A2 (enExample)

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KR20150101477A (ko) * 2012-10-23 2015-09-03 주식회사 툴젠 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도

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EP2858486A4 (en) 2016-04-13
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RU2014153918A (ru) 2016-07-27
US20150128300A1 (en) 2015-05-07
CA2876076A1 (en) 2013-12-19
CN104540382A (zh) 2015-04-22
HK1209276A1 (en) 2016-04-01
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