KR20130101067A - 라임병의 진단 방법 - Google Patents

라임병의 진단 방법 Download PDF

Info

Publication number
KR20130101067A
KR20130101067A KR1020137010849A KR20137010849A KR20130101067A KR 20130101067 A KR20130101067 A KR 20130101067A KR 1020137010849 A KR1020137010849 A KR 1020137010849A KR 20137010849 A KR20137010849 A KR 20137010849A KR 20130101067 A KR20130101067 A KR 20130101067A
Authority
KR
South Korea
Prior art keywords
burgdorferi
antibodies
ospc
ospf
ospa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020137010849A
Other languages
English (en)
Korean (ko)
Inventor
베티나 와그너
Original Assignee
코넬 유니버시티
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 코넬 유니버시티 filed Critical 코넬 유니버시티
Publication of KR20130101067A publication Critical patent/KR20130101067A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020137010849A 2010-09-27 2011-09-27 라임병의 진단 방법 Withdrawn KR20130101067A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38669410P 2010-09-27 2010-09-27
US61/386,694 2010-09-27
PCT/US2011/053359 WO2012047607A2 (en) 2010-09-27 2011-09-27 Methods for diagnosing lyme disease

Publications (1)

Publication Number Publication Date
KR20130101067A true KR20130101067A (ko) 2013-09-12

Family

ID=45928310

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137010849A Withdrawn KR20130101067A (ko) 2010-09-27 2011-09-27 라임병의 진단 방법

Country Status (11)

Country Link
US (1) US8946393B2 (enExample)
EP (1) EP2622346A4 (enExample)
JP (1) JP2013539032A (enExample)
KR (1) KR20130101067A (enExample)
CN (1) CN103229055A (enExample)
BR (1) BR112013007329A2 (enExample)
CA (1) CA2812759A1 (enExample)
MX (1) MX2013003609A (enExample)
RU (1) RU2013118647A (enExample)
WO (1) WO2012047607A2 (enExample)
ZA (1) ZA201302402B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT106942B (pt) 2013-05-15 2020-09-10 STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica
US10457721B2 (en) 2014-08-11 2019-10-29 University Of Massachusetts Anti-OSPA antibodies and methods of use
CN104374921B (zh) * 2014-11-21 2016-09-07 安徽医科大学 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用
AU2016328277B2 (en) 2015-09-25 2022-11-24 Biopeptides Corp. Compositions and methods for diagnosing lyme disease and for predicting lyme disease spirochete elimination after treatment
CN105524989A (zh) * 2015-12-31 2016-04-27 中国疾病预防控制中心传染病预防控制所 用于检测莱姆病螺旋体的rpa引物和探针及检测方法
CN105628918A (zh) * 2016-02-04 2016-06-01 浙江大学 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用
US20220034880A1 (en) * 2018-10-01 2022-02-03 The Board Of Trustees Of The Leland Stanford Junior University High specificity and sensitivity immunosorbent diagnostic assays with simultaneous resolution of multiple antibody isotypes
US20210215715A1 (en) * 2020-01-10 2021-07-15 Quidel Corporation Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics
EP4136251A4 (en) * 2020-04-13 2024-10-02 ID-Fish Technology, Inc. DETECTION OF LYME DISEASE
US20230324382A1 (en) * 2022-02-01 2023-10-12 Trustees Of Tufts College Antiphospholipid antibodies for the diagnosis of lyme disease

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US6300101B1 (en) 1988-10-24 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions including a 13kD B. burgdorferi protein
US5777095A (en) * 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
US6143872A (en) * 1988-10-24 2000-11-07 Symbicom Aktiebolag Borrelia burdorferi Osp A and B proteins and immunogenic peptides
US6872550B1 (en) * 1991-07-11 2005-03-29 Baxter Vaccine Ag Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
US6676942B1 (en) 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
US6248562B1 (en) * 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US7008625B2 (en) * 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US5620862A (en) 1993-11-24 1997-04-15 University Of Connecticut Methods for diagnosing early Lyme disease
PT757556E (pt) * 1994-04-11 2006-10-31 Wyeth Corp Bacterina borrelia burgdorferi
US5558993A (en) * 1994-06-17 1996-09-24 The Regents Of The University Of California Cloned Borrelia burgdorferi virulence protein
CZ42497A3 (en) * 1994-08-17 1997-10-15 Max Planck Gesellschaft VACCINE CONTAINING BORRELIA BURGDORFERI OspG
US5853987A (en) * 1995-04-24 1998-12-29 The Texas A & M University System Decorin binding protein compositions and methods of use
WO1997015600A1 (en) 1995-10-26 1997-05-01 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Tick (ixodes scapularis) vector saliva-induced lyme disease spirochete (borrelia burgdorferi) antigens as vaccine candidates
CA2253374C (en) * 1996-05-02 2004-07-20 Marianne Jartved Mathiesen Novel osp-c derived peptide fragments
US6716574B2 (en) * 1996-05-02 2004-04-06 Dako A/S Osp-C derived peptide fragments
US6902893B1 (en) 1997-06-20 2005-06-07 Gil H. Choi Lyme disease vaccines
CA2294701C (en) 1997-06-30 2009-09-08 The Administrators Of The Tulane Educational Fund Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease
US6610838B1 (en) * 1997-09-10 2003-08-26 Symbicom Aktiebolag P13 antigens from Borrelia
EP1100922B1 (en) 1998-07-31 2008-02-20 Gundersen Lutheran Medical Foundation, Inc. Uses of the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein c (ospc) as vaccine
WO2000018791A1 (en) * 1998-09-29 2000-04-06 Statens Serum Institut Ligand presenting assembly (lpa), method of preparation and uses thereof
US6475492B1 (en) 1999-04-28 2002-11-05 The Administrators Of The Tulane Educational Fund Peptides and assays for the diagnosis of lyme disease
AU5622800A (en) * 1999-06-18 2001-01-09 Med Immune, Inc. Combined decorin binding protein and outer surface protein compositions and methods of use
US20030134345A1 (en) * 2001-07-17 2003-07-17 Michael Brunner Serological assay for detection of antigens sequested within immune complexes
FI112544B (fi) * 2001-11-26 2003-12-15 Bortech Oy Menetelmä varhais- ja myöhäisvaiheen Lymen borrelioosin diagnosoimiseksi
US20050058661A1 (en) 2002-10-18 2005-03-17 Sykes Kathryn F. Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus Borrelia
US8821893B2 (en) * 2004-07-02 2014-09-02 Bio Peptides, Corp. Oral vaccine for Borrelia
US7390626B2 (en) 2005-02-25 2008-06-24 Immunosciences Lab., Inc. Methods and kit for diagnosing tick borne illnesses
CN101374858A (zh) * 2005-11-29 2009-02-25 弗吉尼亚州立大学 多价嵌合ospc疫苗原及诊断抗原
EP1957520A4 (en) * 2005-11-29 2009-05-27 Univ Virginia Commonwealth POLYVALENTIC CHIMERIC OSPC VACCINOGEN AND DIAGNOSTIC ANTIGEN
WO2007133623A2 (en) 2006-05-10 2007-11-22 Biopeptides Corporation Peptide diagnostic agent for lyme disease
CN101516905A (zh) 2006-09-15 2009-08-26 英特塞尔股份公司 疏螺旋体属抗原
EP2191266A4 (en) 2007-09-07 2011-08-03 Univ California BORRELIA DIAGNOSTIC AND SCREENING METHOD
US20110105355A1 (en) 2008-04-22 2011-05-05 Research Foundation Of State University Of New York Borrelia burgdorferi cell envelope protein array
US8565892B2 (en) * 2009-10-31 2013-10-22 Qteris, Inc. Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment
US20130085076A1 (en) * 2009-12-01 2013-04-04 Temple Douglas Borrelia burgdorferi bacterial antigen diagnosic test using polymeric bait containing capture particles
CN103237901B (zh) 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物

Also Published As

Publication number Publication date
US20130273572A1 (en) 2013-10-17
WO2012047607A3 (en) 2012-08-16
ZA201302402B (en) 2014-06-25
RU2013118647A (ru) 2014-11-10
WO2012047607A2 (en) 2012-04-12
EP2622346A4 (en) 2014-04-16
JP2013539032A (ja) 2013-10-17
US8946393B2 (en) 2015-02-03
CA2812759A1 (en) 2012-04-12
BR112013007329A2 (pt) 2016-07-19
MX2013003609A (es) 2013-10-17
CN103229055A (zh) 2013-07-31
EP2622346A2 (en) 2013-08-07

Similar Documents

Publication Publication Date Title
KR20130101067A (ko) 라임병의 진단 방법
US20120142023A1 (en) Proteins and method for detection of lyme disease
JP2021167805A (ja) SARS−CoV−2感染症を診断するための方法および試薬
EP2809348B1 (en) Diagnostic peptides for lyme disease
US20130164759A1 (en) Compositions and methods for screening for lyme disease
CN106468716B (zh) 牙周病原菌血浆或血清抗体效价检测试剂盒
Wagner et al. A fluorescent bead-based multiplex assay for the simultaneous detection of antibodies to B. burgdorferi outer surface proteins in canine serum
US20110105355A1 (en) Borrelia burgdorferi cell envelope protein array
RS56579B1 (sr) Poboljšano dijagnostikovanje vakcina
JP2017531657A (ja) 組換えボレリアタンパク質およびその使用のための方法
CN116528894A (zh) 用于检测SARS-CoV-2的半胱氨酸样蛋白酶(Mpro)的测定
KR20220114257A (ko) PEDV 유래 재조합 스파이크 단백질을 포함하는 PEDV 특이 IgA 검출 키트
US20250298018A1 (en) Test for the detection of antibodies against leishmania
US8338566B2 (en) Characterization of BBK07 antigen of Borrelia burgdorferi and methods of use
US8163500B2 (en) Polypeptides and methods for the specific detection of antibodies in patients with a Borrelia infection
EP3077409B1 (en) Peptides for diagnosing lyme disease
FI112544B (fi) Menetelmä varhais- ja myöhäisvaiheen Lymen borrelioosin diagnosoimiseksi
WO2020158811A1 (ja) ヘリコバクター・ピロリ菌株の同定方法、および同定用キット
US20240353409A1 (en) Novel serology assay for the detection of porcine viruses
KR102089268B1 (ko) 한탄바이러스 절단형 뉴클레오캡시드 단백질을 이용한 한탄바이러스 검출 방법
JP2012511325A (ja) トキソカラ症を検出するための組換え抗原
EP4033247A1 (en) Multi-species immunoassays for detecting antibodies anti-sars-cov-2 using protein a for detection of captured antibodies
WO2018017998A1 (en) Recombinant borrelia proteins and methods of use thereof
Holmqvist Comparison of Two Methods for Detecting Intrathecal Synthesis of Borrelia Specific Antibodies
JP2005263773A (ja) 長期免疫によって認識される重症急性呼吸器症候群コロナウィルス由来ぺプチド

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20130426

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid