CA2812759A1 - Methods for diagnosing lyme disease - Google Patents

Methods for diagnosing lyme disease Download PDF

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Publication number
CA2812759A1
CA2812759A1 CA2812759A CA2812759A CA2812759A1 CA 2812759 A1 CA2812759 A1 CA 2812759A1 CA 2812759 A CA2812759 A CA 2812759A CA 2812759 A CA2812759 A CA 2812759A CA 2812759 A1 CA2812759 A1 CA 2812759A1
Authority
CA
Canada
Prior art keywords
antibodies
burgdorferi
ospc
ospf
ospa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2812759A
Other languages
English (en)
French (fr)
Inventor
Bettina Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell University
Original Assignee
Cornell University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell University filed Critical Cornell University
Publication of CA2812759A1 publication Critical patent/CA2812759A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2812759A 2010-09-27 2011-09-27 Methods for diagnosing lyme disease Abandoned CA2812759A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38669410P 2010-09-27 2010-09-27
US61/386,694 2010-09-27
PCT/US2011/053359 WO2012047607A2 (en) 2010-09-27 2011-09-27 Methods for diagnosing lyme disease

Publications (1)

Publication Number Publication Date
CA2812759A1 true CA2812759A1 (en) 2012-04-12

Family

ID=45928310

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2812759A Abandoned CA2812759A1 (en) 2010-09-27 2011-09-27 Methods for diagnosing lyme disease

Country Status (11)

Country Link
US (1) US8946393B2 (enExample)
EP (1) EP2622346A4 (enExample)
JP (1) JP2013539032A (enExample)
KR (1) KR20130101067A (enExample)
CN (1) CN103229055A (enExample)
BR (1) BR112013007329A2 (enExample)
CA (1) CA2812759A1 (enExample)
MX (1) MX2013003609A (enExample)
RU (1) RU2013118647A (enExample)
WO (1) WO2012047607A2 (enExample)
ZA (1) ZA201302402B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT106942B (pt) 2013-05-15 2020-09-10 STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica
WO2016025331A1 (en) * 2014-08-11 2016-02-18 University Of Massachusetts Anti-ospa antibodies and methods of use
CN104374921B (zh) * 2014-11-21 2016-09-07 安徽医科大学 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用
SG10202110385UA (en) * 2015-09-25 2021-11-29 Qiagen Sciences Llc Compositions and methods for diagnosing lyme disease and for predicting lyme disease spirochete elimination after treatment
CN105524989A (zh) * 2015-12-31 2016-04-27 中国疾病预防控制中心传染病预防控制所 用于检测莱姆病螺旋体的rpa引物和探针及检测方法
CN105628918A (zh) * 2016-02-04 2016-06-01 浙江大学 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用
EP3861344A4 (en) * 2018-10-01 2022-07-20 The Board of Trustees of the Leland Stanford Junior University HIGHLY SPECIFIC AND HIGHLY SENSITIVE DIAGNOSTIC IMMUNODORPTION TESTS WITH SIMULTANEOUS RESOLUTION OF MULTIPLE ANTIBODIES ISOTYPES
WO2021142294A1 (en) * 2020-01-10 2021-07-15 Quidel Corporation Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics
WO2021211637A1 (en) * 2020-04-13 2021-10-21 Id-Fish Technology, Inc. Detection of lyme disease
US20230324382A1 (en) * 2022-02-01 2023-10-12 Trustees Of Tufts College Antiphospholipid antibodies for the diagnosis of lyme disease

Family Cites Families (37)

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DK590288D0 (da) 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US6300101B1 (en) 1988-10-24 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions including a 13kD B. burgdorferi protein
US6143872A (en) * 1988-10-24 2000-11-07 Symbicom Aktiebolag Borrelia burdorferi Osp A and B proteins and immunogenic peptides
US5777095A (en) * 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
US6872550B1 (en) * 1991-07-11 2005-03-29 Baxter Vaccine Ag Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens
US6676942B1 (en) 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
US7008625B2 (en) * 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US6248562B1 (en) * 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US5620862A (en) 1993-11-24 1997-04-15 University Of Connecticut Methods for diagnosing early Lyme disease
US6316005B1 (en) * 1994-04-11 2001-11-13 Solvay Animal Health, Inc. Borrelia burgdorferi bacterin
US5558993A (en) * 1994-06-17 1996-09-24 The Regents Of The University Of California Cloned Borrelia burgdorferi virulence protein
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EP0880543A4 (en) 1995-10-26 2000-08-02 Rhode Island Education ANTIGENS AS VACCINE CANDIDATES FOR THE SPICK-INDUCED LYME DISEASE SPIROCHETES (BORRELIA BURGDORFERI) BY TICK VECTORS (IXODES SCAPULARIS)
US6716574B2 (en) * 1996-05-02 2004-04-06 Dako A/S Osp-C derived peptide fragments
DE896583T1 (de) * 1996-05-02 2000-03-09 Statens Seruminstitut Neue osp-c abgeleitete peptidefragmente
US6902893B1 (en) 1997-06-20 2005-06-07 Gil H. Choi Lyme disease vaccines
ES2270523T3 (es) 1997-06-30 2007-04-01 The Administrators Of The Tulane Educational Fund Antigenos de superficie y proteinas utiles en composiciones para la diagnosis y prevencion de la enfermedad de lyme.
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EP1117677B1 (en) * 1998-09-29 2003-11-12 Statens Serum Institut Ligand presenting assembly (lpa), method of preparation and uses thereof
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US20030134345A1 (en) * 2001-07-17 2003-07-17 Michael Brunner Serological assay for detection of antigens sequested within immune complexes
FI112544B (fi) * 2001-11-26 2003-12-15 Bortech Oy Menetelmä varhais- ja myöhäisvaiheen Lymen borrelioosin diagnosoimiseksi
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Also Published As

Publication number Publication date
EP2622346A4 (en) 2014-04-16
ZA201302402B (en) 2014-06-25
WO2012047607A3 (en) 2012-08-16
US20130273572A1 (en) 2013-10-17
WO2012047607A2 (en) 2012-04-12
EP2622346A2 (en) 2013-08-07
BR112013007329A2 (pt) 2016-07-19
US8946393B2 (en) 2015-02-03
RU2013118647A (ru) 2014-11-10
CN103229055A (zh) 2013-07-31
MX2013003609A (es) 2013-10-17
KR20130101067A (ko) 2013-09-12
JP2013539032A (ja) 2013-10-17

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20160928