JP2013539032A - ライム病の診断方法 - Google Patents
ライム病の診断方法 Download PDFInfo
- Publication number
- JP2013539032A JP2013539032A JP2013530408A JP2013530408A JP2013539032A JP 2013539032 A JP2013539032 A JP 2013539032A JP 2013530408 A JP2013530408 A JP 2013530408A JP 2013530408 A JP2013530408 A JP 2013530408A JP 2013539032 A JP2013539032 A JP 2013539032A
- Authority
- JP
- Japan
- Prior art keywords
- lyme disease
- antibodies
- ospc
- ospf
- ospa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38669410P | 2010-09-27 | 2010-09-27 | |
| US61/386,694 | 2010-09-27 | ||
| PCT/US2011/053359 WO2012047607A2 (en) | 2010-09-27 | 2011-09-27 | Methods for diagnosing lyme disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013539032A true JP2013539032A (ja) | 2013-10-17 |
| JP2013539032A5 JP2013539032A5 (enExample) | 2014-11-20 |
Family
ID=45928310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013530408A Pending JP2013539032A (ja) | 2010-09-27 | 2011-09-27 | ライム病の診断方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8946393B2 (enExample) |
| EP (1) | EP2622346A4 (enExample) |
| JP (1) | JP2013539032A (enExample) |
| KR (1) | KR20130101067A (enExample) |
| CN (1) | CN103229055A (enExample) |
| BR (1) | BR112013007329A2 (enExample) |
| CA (1) | CA2812759A1 (enExample) |
| MX (1) | MX2013003609A (enExample) |
| RU (1) | RU2013118647A (enExample) |
| WO (1) | WO2012047607A2 (enExample) |
| ZA (1) | ZA201302402B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018536429A (ja) * | 2015-09-25 | 2018-12-13 | キアゲン サイエンシス リミテッド ライアビリティ カンパニー | ライム病を診断するためのおよび治療後のライム病スピロヘータ除去を予測するための組成物および方法 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT106942B (pt) | 2013-05-15 | 2020-09-10 | STAB VIDA, Investigação e Serviços em Ciências Biológicas, Lda | Biochip (1) e bouquet de 16 antigénios (2) para a deteção da doença de lyme aguda e crónica |
| US10457721B2 (en) | 2014-08-11 | 2019-10-29 | University Of Massachusetts | Anti-OSPA antibodies and methods of use |
| CN104374921B (zh) * | 2014-11-21 | 2016-09-07 | 安徽医科大学 | 一种用于莱姆病鞭毛抗原免疫血清学诊断的蛋白质芯片及其制备方法和应用 |
| CN105524989A (zh) * | 2015-12-31 | 2016-04-27 | 中国疾病预防控制中心传染病预防控制所 | 用于检测莱姆病螺旋体的rpa引物和探针及检测方法 |
| CN105628918A (zh) * | 2016-02-04 | 2016-06-01 | 浙江大学 | 一种蜱传莱姆病伯氏疏螺旋体检测试剂及应用 |
| US20220034880A1 (en) * | 2018-10-01 | 2022-02-03 | The Board Of Trustees Of The Leland Stanford Junior University | High specificity and sensitivity immunosorbent diagnostic assays with simultaneous resolution of multiple antibody isotypes |
| US20210215715A1 (en) * | 2020-01-10 | 2021-07-15 | Quidel Corporation | Test strip with structured substrate for multiplex lateral flow assay for disease diagnostics |
| EP4136251A4 (en) * | 2020-04-13 | 2024-10-02 | ID-Fish Technology, Inc. | DETECTION OF LYME DISEASE |
| US20230324382A1 (en) * | 2022-02-01 | 2023-10-12 | Trustees Of Tufts College | Antiphospholipid antibodies for the diagnosis of lyme disease |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| US6300101B1 (en) | 1988-10-24 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions including a 13kD B. burgdorferi protein |
| US5777095A (en) * | 1988-10-24 | 1998-07-07 | Symbicom Aktiebolag | Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90 |
| US6143872A (en) * | 1988-10-24 | 2000-11-07 | Symbicom Aktiebolag | Borrelia burdorferi Osp A and B proteins and immunogenic peptides |
| US6872550B1 (en) * | 1991-07-11 | 2005-03-29 | Baxter Vaccine Ag | Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens |
| US6676942B1 (en) | 1991-08-15 | 2004-01-13 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| US6248562B1 (en) * | 1993-11-01 | 2001-06-19 | Research Foundation State University Of New York | Chimeric proteins comprising borrelia polypeptides and uses therefor |
| US7008625B2 (en) * | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| US5620862A (en) | 1993-11-24 | 1997-04-15 | University Of Connecticut | Methods for diagnosing early Lyme disease |
| PT757556E (pt) * | 1994-04-11 | 2006-10-31 | Wyeth Corp | Bacterina borrelia burgdorferi |
| US5558993A (en) * | 1994-06-17 | 1996-09-24 | The Regents Of The University Of California | Cloned Borrelia burgdorferi virulence protein |
| CZ42497A3 (en) * | 1994-08-17 | 1997-10-15 | Max Planck Gesellschaft | VACCINE CONTAINING BORRELIA BURGDORFERI OspG |
| US5853987A (en) * | 1995-04-24 | 1998-12-29 | The Texas A & M University System | Decorin binding protein compositions and methods of use |
| WO1997015600A1 (en) | 1995-10-26 | 1997-05-01 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Tick (ixodes scapularis) vector saliva-induced lyme disease spirochete (borrelia burgdorferi) antigens as vaccine candidates |
| CA2253374C (en) * | 1996-05-02 | 2004-07-20 | Marianne Jartved Mathiesen | Novel osp-c derived peptide fragments |
| US6716574B2 (en) * | 1996-05-02 | 2004-04-06 | Dako A/S | Osp-C derived peptide fragments |
| US6902893B1 (en) | 1997-06-20 | 2005-06-07 | Gil H. Choi | Lyme disease vaccines |
| CA2294701C (en) | 1997-06-30 | 2009-09-08 | The Administrators Of The Tulane Educational Fund | Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease |
| US6610838B1 (en) * | 1997-09-10 | 2003-08-26 | Symbicom Aktiebolag | P13 antigens from Borrelia |
| EP1100922B1 (en) | 1998-07-31 | 2008-02-20 | Gundersen Lutheran Medical Foundation, Inc. | Uses of the borreliacidal epitope(s) of borrelia burgdorferi outer surface protein c (ospc) as vaccine |
| WO2000018791A1 (en) * | 1998-09-29 | 2000-04-06 | Statens Serum Institut | Ligand presenting assembly (lpa), method of preparation and uses thereof |
| US6475492B1 (en) | 1999-04-28 | 2002-11-05 | The Administrators Of The Tulane Educational Fund | Peptides and assays for the diagnosis of lyme disease |
| AU5622800A (en) * | 1999-06-18 | 2001-01-09 | Med Immune, Inc. | Combined decorin binding protein and outer surface protein compositions and methods of use |
| US20030134345A1 (en) * | 2001-07-17 | 2003-07-17 | Michael Brunner | Serological assay for detection of antigens sequested within immune complexes |
| FI112544B (fi) * | 2001-11-26 | 2003-12-15 | Bortech Oy | Menetelmä varhais- ja myöhäisvaiheen Lymen borrelioosin diagnosoimiseksi |
| US20050058661A1 (en) | 2002-10-18 | 2005-03-17 | Sykes Kathryn F. | Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus Borrelia |
| US8821893B2 (en) * | 2004-07-02 | 2014-09-02 | Bio Peptides, Corp. | Oral vaccine for Borrelia |
| US7390626B2 (en) | 2005-02-25 | 2008-06-24 | Immunosciences Lab., Inc. | Methods and kit for diagnosing tick borne illnesses |
| CN101374858A (zh) * | 2005-11-29 | 2009-02-25 | 弗吉尼亚州立大学 | 多价嵌合ospc疫苗原及诊断抗原 |
| EP1957520A4 (en) * | 2005-11-29 | 2009-05-27 | Univ Virginia Commonwealth | POLYVALENTIC CHIMERIC OSPC VACCINOGEN AND DIAGNOSTIC ANTIGEN |
| WO2007133623A2 (en) | 2006-05-10 | 2007-11-22 | Biopeptides Corporation | Peptide diagnostic agent for lyme disease |
| CN101516905A (zh) | 2006-09-15 | 2009-08-26 | 英特塞尔股份公司 | 疏螺旋体属抗原 |
| EP2191266A4 (en) | 2007-09-07 | 2011-08-03 | Univ California | BORRELIA DIAGNOSTIC AND SCREENING METHOD |
| US20110105355A1 (en) | 2008-04-22 | 2011-05-05 | Research Foundation Of State University Of New York | Borrelia burgdorferi cell envelope protein array |
| US8565892B2 (en) * | 2009-10-31 | 2013-10-22 | Qteris, Inc. | Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment |
| US20130085076A1 (en) * | 2009-12-01 | 2013-04-04 | Temple Douglas | Borrelia burgdorferi bacterial antigen diagnosic test using polymeric bait containing capture particles |
| CN103237901B (zh) | 2010-03-01 | 2016-08-03 | 卡里斯生命科学瑞士控股有限责任公司 | 用于治疗诊断的生物标志物 |
-
2011
- 2011-09-27 WO PCT/US2011/053359 patent/WO2012047607A2/en not_active Ceased
- 2011-09-27 JP JP2013530408A patent/JP2013539032A/ja active Pending
- 2011-09-27 EP EP11831265.1A patent/EP2622346A4/en not_active Withdrawn
- 2011-09-27 US US13/876,077 patent/US8946393B2/en active Active
- 2011-09-27 KR KR1020137010849A patent/KR20130101067A/ko not_active Withdrawn
- 2011-09-27 BR BR112013007329A patent/BR112013007329A2/pt not_active IP Right Cessation
- 2011-09-27 MX MX2013003609A patent/MX2013003609A/es not_active Application Discontinuation
- 2011-09-27 CA CA2812759A patent/CA2812759A1/en not_active Abandoned
- 2011-09-27 RU RU2013118647/15A patent/RU2013118647A/ru not_active Application Discontinuation
- 2011-09-27 CN CN2011800562501A patent/CN103229055A/zh active Pending
-
2013
- 2013-04-03 ZA ZA2013/02402A patent/ZA201302402B/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018536429A (ja) * | 2015-09-25 | 2018-12-13 | キアゲン サイエンシス リミテッド ライアビリティ カンパニー | ライム病を診断するためのおよび治療後のライム病スピロヘータ除去を予測するための組成物および方法 |
| US10983121B2 (en) | 2015-09-25 | 2021-04-20 | Qiagen Sciences Llc | Compositions and methods for diagnosing Lyme disease and for predicting Lyme disease spirochete elimination after treatment |
| US12066436B2 (en) | 2015-09-25 | 2024-08-20 | Qiagen Sciences Llc | Compositions and methods for diagnosing Lyme disease and for predicting Lyme disease spirochete elimination after treatment |
Also Published As
| Publication number | Publication date |
|---|---|
| US20130273572A1 (en) | 2013-10-17 |
| WO2012047607A3 (en) | 2012-08-16 |
| KR20130101067A (ko) | 2013-09-12 |
| ZA201302402B (en) | 2014-06-25 |
| RU2013118647A (ru) | 2014-11-10 |
| WO2012047607A2 (en) | 2012-04-12 |
| EP2622346A4 (en) | 2014-04-16 |
| US8946393B2 (en) | 2015-02-03 |
| CA2812759A1 (en) | 2012-04-12 |
| BR112013007329A2 (pt) | 2016-07-19 |
| MX2013003609A (es) | 2013-10-17 |
| CN103229055A (zh) | 2013-07-31 |
| EP2622346A2 (en) | 2013-08-07 |
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