KR20080109096A - 연령 관련 황반 변성(에이엠디)의 치료 방법 - Google Patents

연령 관련 황반 변성(에이엠디)의 치료 방법 Download PDF

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Publication number
KR20080109096A
KR20080109096A KR1020087027935A KR20087027935A KR20080109096A KR 20080109096 A KR20080109096 A KR 20080109096A KR 1020087027935 A KR1020087027935 A KR 1020087027935A KR 20087027935 A KR20087027935 A KR 20087027935A KR 20080109096 A KR20080109096 A KR 20080109096A
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KR
South Korea
Prior art keywords
optionally substituted
patient
amd
compounds
macular degeneration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR1020087027935A
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English (en)
Korean (ko)
Inventor
애슬리 부쉬
콜린 루이스 마스터스
페넬로페 제인 휴긴스
잭 고든 파슨스
가익 벵 콕
비쟈야 켄체
마리아나 엘 수스
Original Assignee
프라나 바이오테크놀로지 리미티드
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Publication of KR20080109096A publication Critical patent/KR20080109096A/ko
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020087027935A 2006-04-14 2007-04-13 연령 관련 황반 변성(에이엠디)의 치료 방법 Ceased KR20080109096A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79227806P 2006-04-14 2006-04-14
US60/792,278 2006-04-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020107020805A Division KR20100110396A (ko) 2006-04-14 2007-04-13 연령 관련 황반 변성(에이엠디)의 치료 방법

Publications (1)

Publication Number Publication Date
KR20080109096A true KR20080109096A (ko) 2008-12-16

Family

ID=38608967

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020087027935A Ceased KR20080109096A (ko) 2006-04-14 2007-04-13 연령 관련 황반 변성(에이엠디)의 치료 방법
KR1020107020805A Ceased KR20100110396A (ko) 2006-04-14 2007-04-13 연령 관련 황반 변성(에이엠디)의 치료 방법

Family Applications After (1)

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KR1020107020805A Ceased KR20100110396A (ko) 2006-04-14 2007-04-13 연령 관련 황반 변성(에이엠디)의 치료 방법

Country Status (14)

Country Link
US (3) US20100144693A1 (https=)
EP (2) EP2012789B1 (https=)
JP (1) JP5290147B2 (https=)
KR (2) KR20080109096A (https=)
CN (3) CN101987849B (https=)
AU (2) AU2007240120A1 (https=)
BR (2) BRPI0722382A2 (https=)
CA (1) CA2683756A1 (https=)
DK (1) DK2012789T3 (https=)
ES (1) ES2437997T3 (https=)
IL (1) IL207495A (https=)
NZ (2) NZ572591A (https=)
WO (1) WO2007118276A1 (https=)
ZA (2) ZA200809493B (https=)

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WO2012122534A2 (en) 2011-03-10 2012-09-13 The Trustees Of Columbia University In The City Of New York N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation
AU2013207796B2 (en) 2012-01-13 2017-04-27 President And Fellows Of Harvard College Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions
RU2015120478A (ru) * 2012-12-20 2017-01-25 Альдейра Терапьютикс, Инк. Пери-карбинолы
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CN107533181B (zh) * 2015-04-29 2020-06-30 特里亚佩克斯有限公司 偏光膜、制备它的方法及包含它的偏光镜片
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CN113784954A (zh) 2019-05-02 2021-12-10 奥尔德拉医疗公司 多晶型化合物和其用途
CA3175856A1 (en) 2020-05-13 2021-11-18 Todd Brady Pharmaceutical formulations and uses thereof
WO2022006439A2 (en) * 2020-07-02 2022-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compound embodiments for treating retinal degeneration and method embodiments of making and using the same
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CN113214249B (zh) * 2021-04-23 2023-09-19 成都大学 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法

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Also Published As

Publication number Publication date
CN101987849B (zh) 2013-05-08
CN101987849A (zh) 2011-03-23
US20110071167A1 (en) 2011-03-24
KR20100110396A (ko) 2010-10-12
WO2007118276A1 (en) 2007-10-25
US9163018B2 (en) 2015-10-20
US20140088122A1 (en) 2014-03-27
AU2010206074A1 (en) 2010-08-19
ES2437997T3 (es) 2014-01-15
NZ572591A (en) 2012-01-12
AU2007240120A2 (en) 2008-12-18
AU2007240120A1 (en) 2007-10-25
EP2012789B1 (en) 2013-09-25
ZA200809493B (en) 2010-08-25
US20100144693A1 (en) 2010-06-10
NZ590271A (en) 2011-12-22
EP2514423A3 (en) 2012-12-19
EP2012789A1 (en) 2009-01-14
JP2009533356A (ja) 2009-09-17
DK2012789T3 (da) 2013-12-16
EP2514423A2 (en) 2012-10-24
EP2012789A4 (en) 2011-02-16
JP5290147B2 (ja) 2013-09-18
IL207495A (en) 2015-05-31
ZA201005922B (en) 2013-09-25
IL207495A0 (en) 2010-12-30
BRPI0722382A2 (pt) 2012-06-05
CN102225930A (zh) 2011-10-26
BRPI0710737A2 (pt) 2011-05-10
AU2010206074B2 (en) 2012-08-30
CA2683756A1 (en) 2007-10-25
CN101534826A (zh) 2009-09-16

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