AU2007240120A1 - Method of treatment of age-related macular degeneration (AMD) - Google Patents

Method of treatment of age-related macular degeneration (AMD) Download PDF

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Publication number
AU2007240120A1
AU2007240120A1 AU2007240120A AU2007240120A AU2007240120A1 AU 2007240120 A1 AU2007240120 A1 AU 2007240120A1 AU 2007240120 A AU2007240120 A AU 2007240120A AU 2007240120 A AU2007240120 A AU 2007240120A AU 2007240120 A1 AU2007240120 A1 AU 2007240120A1
Authority
AU
Australia
Prior art keywords
optionally substituted
cells
pct
neuronal
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007240120A
Other languages
English (en)
Other versions
AU2007240120A2 (en
Inventor
Mariana El Sous
Penelope Jane Huggins
Vijaya Kenche
Gaik Beng Kok
Jack Gordon Parsons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alterity Therapeutics Ltd
Original Assignee
Prana Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prana Biotechnology Ltd filed Critical Prana Biotechnology Ltd
Publication of AU2007240120A1 publication Critical patent/AU2007240120A1/en
Publication of AU2007240120A2 publication Critical patent/AU2007240120A2/en
Priority to AU2010206074A priority Critical patent/AU2010206074B2/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007240120A 2006-04-14 2007-04-13 Method of treatment of age-related macular degeneration (AMD) Abandoned AU2007240120A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010206074A AU2010206074B2 (en) 2006-04-14 2010-07-30 Method of treatment of age-related macular degeneration (AMD)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79227806P 2006-04-14 2006-04-14
US60/792,278 2006-04-14
PCT/AU2007/000490 WO2007118276A1 (en) 2006-04-14 2007-04-13 Method of treatment of age-related macular degeneration(amd)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010206074A Division AU2010206074B2 (en) 2006-04-14 2010-07-30 Method of treatment of age-related macular degeneration (AMD)

Publications (2)

Publication Number Publication Date
AU2007240120A1 true AU2007240120A1 (en) 2007-10-25
AU2007240120A2 AU2007240120A2 (en) 2008-12-18

Family

ID=38608967

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2007240120A Abandoned AU2007240120A1 (en) 2006-04-14 2007-04-13 Method of treatment of age-related macular degeneration (AMD)
AU2010206074A Ceased AU2010206074B2 (en) 2006-04-14 2010-07-30 Method of treatment of age-related macular degeneration (AMD)

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2010206074A Ceased AU2010206074B2 (en) 2006-04-14 2010-07-30 Method of treatment of age-related macular degeneration (AMD)

Country Status (14)

Country Link
US (3) US20100144693A1 (https=)
EP (2) EP2012789B1 (https=)
JP (1) JP5290147B2 (https=)
KR (2) KR20080109096A (https=)
CN (3) CN101987849B (https=)
AU (2) AU2007240120A1 (https=)
BR (2) BRPI0722382A2 (https=)
CA (1) CA2683756A1 (https=)
DK (1) DK2012789T3 (https=)
ES (1) ES2437997T3 (https=)
IL (1) IL207495A (https=)
NZ (2) NZ572591A (https=)
WO (1) WO2007118276A1 (https=)
ZA (2) ZA200809493B (https=)

Cited By (1)

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AU2007262670B2 (en) * 2006-06-22 2012-12-20 Prana Biotechnology Limited Method of treatment of glioma brain tumour

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US9284297B2 (en) * 2008-08-11 2016-03-15 President And Fellows Of Harvard College Halofuginone analogs for inhibition of tRNA synthetases and uses thereof
US8889695B2 (en) 2008-12-24 2014-11-18 Prana Biotechnology Limited Quinazolinone compounds
MA33090B1 (fr) 2009-01-26 2012-03-01 Michael Spino Utilisation de deferiprone pour le traitement et la prevention de troubles oculaires lies au fer
WO2011072141A1 (en) 2009-12-11 2011-06-16 Neuron Systems, Inc. Compositions and methods for the treatment of macular degeneration
WO2012122534A2 (en) 2011-03-10 2012-09-13 The Trustees Of Columbia University In The City Of New York N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation
AU2013207796B2 (en) 2012-01-13 2017-04-27 President And Fellows Of Harvard College Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions
RU2015120478A (ru) * 2012-12-20 2017-01-25 Альдейра Терапьютикс, Инк. Пери-карбинолы
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SG11201505599YA (en) 2013-01-25 2015-08-28 Aldeyra Therapeutics Inc Novel traps in the treatment of macular degeneration
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CN107533181B (zh) * 2015-04-29 2020-06-30 特里亚佩克斯有限公司 偏光膜、制备它的方法及包含它的偏光镜片
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WO2022006439A2 (en) * 2020-07-02 2022-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compound embodiments for treating retinal degeneration and method embodiments of making and using the same
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007262670B2 (en) * 2006-06-22 2012-12-20 Prana Biotechnology Limited Method of treatment of glioma brain tumour

Also Published As

Publication number Publication date
CN101987849B (zh) 2013-05-08
CN101987849A (zh) 2011-03-23
US20110071167A1 (en) 2011-03-24
KR20100110396A (ko) 2010-10-12
KR20080109096A (ko) 2008-12-16
WO2007118276A1 (en) 2007-10-25
US9163018B2 (en) 2015-10-20
US20140088122A1 (en) 2014-03-27
AU2010206074A1 (en) 2010-08-19
ES2437997T3 (es) 2014-01-15
NZ572591A (en) 2012-01-12
AU2007240120A2 (en) 2008-12-18
EP2012789B1 (en) 2013-09-25
ZA200809493B (en) 2010-08-25
US20100144693A1 (en) 2010-06-10
NZ590271A (en) 2011-12-22
EP2514423A3 (en) 2012-12-19
EP2012789A1 (en) 2009-01-14
JP2009533356A (ja) 2009-09-17
DK2012789T3 (da) 2013-12-16
EP2514423A2 (en) 2012-10-24
EP2012789A4 (en) 2011-02-16
JP5290147B2 (ja) 2013-09-18
IL207495A (en) 2015-05-31
ZA201005922B (en) 2013-09-25
IL207495A0 (en) 2010-12-30
BRPI0722382A2 (pt) 2012-06-05
CN102225930A (zh) 2011-10-26
BRPI0710737A2 (pt) 2011-05-10
AU2010206074B2 (en) 2012-08-30
CA2683756A1 (en) 2007-10-25
CN101534826A (zh) 2009-09-16

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