ZA200809493B - Method of treatment of age-related macular degeneration (AMD) - Google Patents
Method of treatment of age-related macular degeneration (AMD)Info
- Publication number
- ZA200809493B ZA200809493B ZA200809493A ZA200809493A ZA200809493B ZA 200809493 B ZA200809493 B ZA 200809493B ZA 200809493 A ZA200809493 A ZA 200809493A ZA 200809493 A ZA200809493 A ZA 200809493A ZA 200809493 B ZA200809493 B ZA 200809493B
- Authority
- ZA
- South Africa
- Prior art keywords
- amd
- age
- treatment
- macular degeneration
- related macular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79227806P | 2006-04-14 | 2006-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200809493B true ZA200809493B (en) | 2010-08-25 |
Family
ID=38608967
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200809493A ZA200809493B (en) | 2006-04-14 | 2007-04-13 | Method of treatment of age-related macular degeneration (AMD) |
ZA2010/05922A ZA201005922B (en) | 2006-04-14 | 2010-08-19 | Method of treatment of age-related macular degeneration (amd) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA2010/05922A ZA201005922B (en) | 2006-04-14 | 2010-08-19 | Method of treatment of age-related macular degeneration (amd) |
Country Status (14)
Country | Link |
---|---|
US (3) | US20100144693A1 (xx) |
EP (2) | EP2514423A3 (xx) |
JP (1) | JP5290147B2 (xx) |
KR (2) | KR20080109096A (xx) |
CN (3) | CN102225930A (xx) |
AU (2) | AU2007240120A1 (xx) |
BR (2) | BRPI0710737A2 (xx) |
CA (1) | CA2683756A1 (xx) |
DK (1) | DK2012789T3 (xx) |
ES (1) | ES2437997T3 (xx) |
IL (1) | IL207495A (xx) |
NZ (2) | NZ590271A (xx) |
WO (1) | WO2007118276A1 (xx) |
ZA (2) | ZA200809493B (xx) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
ES2393768T3 (es) | 2005-05-26 | 2012-12-27 | Neuron Systems, Inc | Derivado de quinolina para el tratamiento de enfermedades retinianas |
JP5415942B2 (ja) * | 2006-06-22 | 2014-02-12 | プラナ バイオテクノロジー リミティッド | 処置の方法およびその処置に有用な薬剤 |
US9284297B2 (en) * | 2008-08-11 | 2016-03-15 | President And Fellows Of Harvard College | Halofuginone analogs for inhibition of tRNA synthetases and uses thereof |
JP5719779B2 (ja) * | 2008-12-24 | 2015-05-20 | プラナ バイオテクノロジー リミティッド | キナゾリノン化合物 |
UA103366C2 (ru) | 2009-01-26 | 2013-10-10 | Майкл Спіно | Применение деферипрона для лечения и профилактики связанных с железом глазных расстройств |
CA2782015C (en) | 2009-12-11 | 2020-08-25 | Neuron Systems, Inc. | Topical ophthalmic compositions and methods for the treatment of macular degeneration |
WO2012122534A2 (en) | 2011-03-10 | 2012-09-13 | The Trustees Of Columbia University In The City Of New York | N-quinolin-benzensulfonamides and related compounds for the treatment of cancer, autoimmune disorders and inflammation |
CA2861840C (en) | 2012-01-13 | 2020-12-15 | President And Fellows Of Harvard College | Halofuginol derivatives and their use in cosmetic and pharmaceutical compositions |
SG11201504859YA (en) * | 2012-12-20 | 2015-07-30 | Aldeyra Therapeutics Inc | Peri-carbinols |
RU2018145691A (ru) | 2013-01-23 | 2019-04-01 | Альдейра Терапьютикс, Инк. | Заболевания, связанные с токсичным альдегидом, и их лечение |
RU2015126015A (ru) | 2013-01-25 | 2017-03-03 | Альдейра Терапьютикс, Инк. | Новые улавливатели в лечении макулодистрофии |
US10287285B2 (en) * | 2014-12-02 | 2019-05-14 | Prana Biotechnology Limited | 4H-pyrido[1,2-A]pyrimidin-4-one compounds |
EP3290969B1 (en) * | 2015-04-29 | 2021-06-23 | Triapex Co., Ltd. | Polarizing lens including a polarizing film |
US10781178B2 (en) * | 2015-08-12 | 2020-09-22 | The General Hospital Corporation | 8-hydroxyquinoline derivatives as diagnostic and therapeutic agents |
CN108135907A (zh) | 2015-08-21 | 2018-06-08 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
WO2017053696A2 (en) * | 2015-09-24 | 2017-03-30 | University Of Florida Research Foundation, Incorporated | Halogenated quinoline derivatives as antimicrobial agents |
WO2017196881A1 (en) | 2016-05-09 | 2017-11-16 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
JP7025358B2 (ja) * | 2016-07-01 | 2022-02-24 | オールテリティ セラピューティクス リミテッド | 免疫グロブリン軽鎖アミロイドーシスを治療する方法 |
AU2018234919A1 (en) | 2017-03-16 | 2019-09-19 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
US11040039B2 (en) | 2017-10-10 | 2021-06-22 | Aldeyra Therapeutics, Inc. | Treatment of inflammatory disorders |
US11708353B2 (en) | 2018-06-08 | 2023-07-25 | The General Hospital Corporation | Inhibitors of prolyl-tRNA-synthetase |
EP3833660A4 (en) | 2018-08-06 | 2022-05-11 | Aldeyra Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND THEIR USES |
CN109232396B (zh) * | 2018-11-27 | 2020-07-03 | 聊城大学 | 酰胺吡啶类衍生物及其用途 |
JP2023532134A (ja) * | 2020-07-02 | 2023-07-26 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 網膜変性の処置において使用するための環式化合物 |
CN113214249B (zh) * | 2021-04-23 | 2023-09-19 | 成都大学 | 吡啶并[1,2-a]嘧啶-4-硫酮化合物的合成方法 |
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US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
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US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
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DE59400560D1 (de) | 1993-04-08 | 1996-10-02 | Ideal Standard | Sanitäres wasserventil |
US5631373A (en) | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
GB9404485D0 (en) | 1994-03-09 | 1994-04-20 | Cancer Res Campaign Tech | Benzamide analogues |
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US5801183A (en) | 1995-01-27 | 1998-09-01 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists |
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US20020025944A1 (en) * | 2000-04-28 | 2002-02-28 | Bush Ashley I. | Use of clioquinol for the therapy of Alzheimer's disease |
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AUPR201600A0 (en) | 2000-12-11 | 2001-01-11 | Fujisawa Pharmaceutical Co., Ltd. | Quinazolinone derivative |
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FR2819187A1 (fr) * | 2001-01-10 | 2002-07-12 | Michel Xilinas | Utilisation des substances chelatrices pour le traitement et la prevention de la deferrescence oculaire |
ATE427948T1 (de) | 2001-04-24 | 2009-04-15 | Purdue Research Foundation | Folat-mimetika und deren folatrezeptorbindende konjugate |
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CA2456155A1 (en) | 2001-08-17 | 2003-02-27 | Merck & Co., Inc. | Process for preparing 5-sulfonamido-8-hydroxy-1, 6-naphthyridine-7-carboxamides |
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MXPA05003607A (es) * | 2002-10-04 | 2005-11-17 | Prana Biotechnology Ltd | Compuestos neurologicamente activos. |
AU2002951868A0 (en) * | 2002-10-04 | 2002-10-24 | Prana Biotechnology Limited | Compound i |
US20070037848A1 (en) * | 2003-04-03 | 2007-02-15 | Masters Colin L | Treatment of neurological conditions |
JP5146714B2 (ja) * | 2003-06-23 | 2013-02-20 | ビーエイチアイ リミテッド パートナーシップ | アミロイド関連疾患を治療するための方法および組成物 |
ES2425476T3 (es) * | 2004-04-02 | 2013-10-15 | Prana Biotechnology Limited | Compuestos neurológicamente activos |
AU2006211625A1 (en) * | 2005-01-14 | 2006-08-10 | The Regents Of The University Of California | Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders |
WO2006117660A2 (en) * | 2005-05-04 | 2006-11-09 | Clio Pharmaceutical Corporation | Method for treating cancer, coronary, inflammatory and macular disease, combining the modulation of zinc- and/or copper dependent proteins |
JP5415942B2 (ja) * | 2006-06-22 | 2014-02-12 | プラナ バイオテクノロジー リミティッド | 処置の方法およびその処置に有用な薬剤 |
-
2007
- 2007-04-13 KR KR1020087027935A patent/KR20080109096A/ko not_active Application Discontinuation
- 2007-04-13 ES ES07718737.5T patent/ES2437997T3/es active Active
- 2007-04-13 BR BRPI0710737-4A patent/BRPI0710737A2/pt not_active IP Right Cessation
- 2007-04-13 ZA ZA200809493A patent/ZA200809493B/xx unknown
- 2007-04-13 KR KR1020107020805A patent/KR20100110396A/ko not_active Application Discontinuation
- 2007-04-13 AU AU2007240120A patent/AU2007240120A1/en not_active Abandoned
- 2007-04-13 CN CN2011101585377A patent/CN102225930A/zh active Pending
- 2007-04-13 EP EP12176495A patent/EP2514423A3/en not_active Withdrawn
- 2007-04-13 BR BRPI0722382-0A patent/BRPI0722382A2/pt not_active Application Discontinuation
- 2007-04-13 US US12/297,165 patent/US20100144693A1/en not_active Abandoned
- 2007-04-13 NZ NZ590271A patent/NZ590271A/en unknown
- 2007-04-13 CN CNA2007800222734A patent/CN101534826A/zh active Pending
- 2007-04-13 JP JP2009504530A patent/JP5290147B2/ja not_active Expired - Fee Related
- 2007-04-13 DK DK07718737.5T patent/DK2012789T3/da active
- 2007-04-13 CN CN2010102559981A patent/CN101987849B/zh not_active Expired - Fee Related
- 2007-04-13 CA CA002683756A patent/CA2683756A1/en not_active Abandoned
- 2007-04-13 NZ NZ572591A patent/NZ572591A/en not_active IP Right Cessation
- 2007-04-13 WO PCT/AU2007/000490 patent/WO2007118276A1/en active Application Filing
- 2007-04-13 EP EP07718737.5A patent/EP2012789B1/en not_active Not-in-force
-
2010
- 2010-07-30 AU AU2010206074A patent/AU2010206074B2/en not_active Ceased
- 2010-08-09 IL IL207495A patent/IL207495A/en active IP Right Grant
- 2010-08-19 ZA ZA2010/05922A patent/ZA201005922B/en unknown
- 2010-11-23 US US12/952,425 patent/US20110071167A1/en not_active Abandoned
-
2013
- 2013-11-22 US US14/087,689 patent/US9163018B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20100144693A1 (en) | 2010-06-10 |
JP2009533356A (ja) | 2009-09-17 |
WO2007118276A1 (en) | 2007-10-25 |
JP5290147B2 (ja) | 2013-09-18 |
US20110071167A1 (en) | 2011-03-24 |
US9163018B2 (en) | 2015-10-20 |
ZA201005922B (en) | 2013-09-25 |
CA2683756A1 (en) | 2007-10-25 |
AU2007240120A1 (en) | 2007-10-25 |
BRPI0722382A2 (pt) | 2012-06-05 |
CN101534826A (zh) | 2009-09-16 |
KR20080109096A (ko) | 2008-12-16 |
NZ572591A (en) | 2012-01-12 |
DK2012789T3 (da) | 2013-12-16 |
AU2010206074B2 (en) | 2012-08-30 |
EP2514423A2 (en) | 2012-10-24 |
US20140088122A1 (en) | 2014-03-27 |
NZ590271A (en) | 2011-12-22 |
EP2012789B1 (en) | 2013-09-25 |
IL207495A0 (en) | 2010-12-30 |
CN101987849A (zh) | 2011-03-23 |
EP2012789A1 (en) | 2009-01-14 |
AU2010206074A1 (en) | 2010-08-19 |
ES2437997T3 (es) | 2014-01-15 |
EP2012789A4 (en) | 2011-02-16 |
AU2007240120A2 (en) | 2008-12-18 |
IL207495A (en) | 2015-05-31 |
BRPI0710737A2 (pt) | 2011-05-10 |
CN101987849B (zh) | 2013-05-08 |
CN102225930A (zh) | 2011-10-26 |
KR20100110396A (ko) | 2010-10-12 |
EP2514423A3 (en) | 2012-12-19 |
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