KR20080108291A - P 물질 길항제로서 유용한 아실아미노알케닐렌 아미드의 합성 - Google Patents

P 물질 길항제로서 유용한 아실아미노알케닐렌 아미드의 합성 Download PDF

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Publication number
KR20080108291A
KR20080108291A KR1020087024839A KR20087024839A KR20080108291A KR 20080108291 A KR20080108291 A KR 20080108291A KR 1020087024839 A KR1020087024839 A KR 1020087024839A KR 20087024839 A KR20087024839 A KR 20087024839A KR 20080108291 A KR20080108291 A KR 20080108291A
Authority
KR
South Korea
Prior art keywords
formula
compound
protecting group
alkyl
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020087024839A
Other languages
English (en)
Korean (ko)
Inventor
로버트 포트만
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0607532A external-priority patent/GB0607532D0/en
Priority claimed from GB0610244A external-priority patent/GB0610244D0/en
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20080108291A publication Critical patent/KR20080108291A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020087024839A 2006-04-13 2007-04-11 P 물질 길항제로서 유용한 아실아미노알케닐렌 아미드의 합성 Ceased KR20080108291A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0607532A GB0607532D0 (en) 2006-04-13 2006-04-13 Organic compounds
GB0607532.9 2006-04-13
GB0610244A GB0610244D0 (en) 2006-05-23 2006-05-23 Organic compounds
GB0610244.6 2006-05-23

Publications (1)

Publication Number Publication Date
KR20080108291A true KR20080108291A (ko) 2008-12-12

Family

ID=38324102

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087024839A Ceased KR20080108291A (ko) 2006-04-13 2007-04-11 P 물질 길항제로서 유용한 아실아미노알케닐렌 아미드의 합성

Country Status (28)

Country Link
US (2) US8008479B2 (enExample)
EP (1) EP2010498B1 (enExample)
JP (1) JP5208917B2 (enExample)
KR (1) KR20080108291A (enExample)
AR (1) AR060506A1 (enExample)
AT (1) ATE486853T1 (enExample)
AU (1) AU2007237482B2 (enExample)
CA (1) CA2645362C (enExample)
CL (1) CL2007001040A1 (enExample)
CY (1) CY1111294T1 (enExample)
DE (1) DE602007010269D1 (enExample)
DK (1) DK2010498T3 (enExample)
EC (1) ECSP088820A (enExample)
GT (1) GT200800209A (enExample)
HR (1) HRP20110045T1 (enExample)
JO (1) JO2630B1 (enExample)
MA (1) MA30394B1 (enExample)
MX (1) MX2008013117A (enExample)
MY (1) MY145069A (enExample)
NO (1) NO20084783L (enExample)
NZ (1) NZ571142A (enExample)
PE (1) PE20071223A1 (enExample)
PL (1) PL2010498T3 (enExample)
PT (1) PT2010498E (enExample)
RU (1) RU2433122C2 (enExample)
SI (1) SI2010498T1 (enExample)
TW (1) TW200815358A (enExample)
WO (1) WO2007118651A1 (enExample)

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US20110217667A1 (en) * 2010-03-08 2011-09-08 Groscurth Randall C Custom linkable imaging and multifunctional tray

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US20110217667A1 (en) * 2010-03-08 2011-09-08 Groscurth Randall C Custom linkable imaging and multifunctional tray
US9226801B2 (en) * 2010-03-08 2016-01-05 Ibur, Llc Custom linkable imaging and multifunctional tray

Also Published As

Publication number Publication date
HK1125640A1 (en) 2009-08-14
ECSP088820A (es) 2008-11-27
DE602007010269D1 (de) 2010-12-16
WO2007118651A1 (en) 2007-10-25
US20110282053A1 (en) 2011-11-17
CA2645362A1 (en) 2007-10-25
US20090137797A1 (en) 2009-05-28
RU2008145102A (ru) 2010-05-27
PT2010498E (pt) 2011-02-08
GT200800209A (es) 2008-12-15
CL2007001040A1 (es) 2008-03-14
AR060506A1 (es) 2008-06-25
PL2010498T3 (pl) 2011-04-29
CY1111294T1 (el) 2015-08-05
JP2009533369A (ja) 2009-09-17
JP5208917B2 (ja) 2013-06-12
RU2433122C2 (ru) 2011-11-10
EP2010498A1 (en) 2009-01-07
DK2010498T3 (da) 2011-02-14
NO20084783L (no) 2008-11-12
CA2645362C (en) 2013-07-16
AU2007237482A1 (en) 2007-10-25
ATE486853T1 (de) 2010-11-15
TW200815358A (en) 2008-04-01
US8008479B2 (en) 2011-08-30
HRP20110045T1 (hr) 2011-02-28
JO2630B1 (en) 2012-06-17
PE20071223A1 (es) 2008-01-22
NZ571142A (en) 2011-02-25
AU2007237482B2 (en) 2011-03-17
MX2008013117A (es) 2008-10-21
MY145069A (en) 2011-12-15
SI2010498T1 (sl) 2011-03-31
EP2010498B1 (en) 2010-11-03
MA30394B1 (fr) 2009-05-04

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