DE602007010269D1 - Synthese von acylaminoalkenylenamiden als substanz-p-antagonisten - Google Patents
Synthese von acylaminoalkenylenamiden als substanz-p-antagonistenInfo
- Publication number
- DE602007010269D1 DE602007010269D1 DE602007010269T DE602007010269T DE602007010269D1 DE 602007010269 D1 DE602007010269 D1 DE 602007010269D1 DE 602007010269 T DE602007010269 T DE 602007010269T DE 602007010269 T DE602007010269 T DE 602007010269T DE 602007010269 D1 DE602007010269 D1 DE 602007010269D1
- Authority
- DE
- Germany
- Prior art keywords
- alkenylenamides
- acylamino
- antagonists
- synthesis
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0607532A GB0607532D0 (en) | 2006-04-13 | 2006-04-13 | Organic compounds |
| GB0610244A GB0610244D0 (en) | 2006-05-23 | 2006-05-23 | Organic compounds |
| PCT/EP2007/003213 WO2007118651A1 (en) | 2006-04-13 | 2007-04-11 | Synthesis of acylaminoalkenylene amides useful as substance p antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602007010269D1 true DE602007010269D1 (de) | 2010-12-16 |
Family
ID=38324102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602007010269T Active DE602007010269D1 (de) | 2006-04-13 | 2007-04-11 | Synthese von acylaminoalkenylenamiden als substanz-p-antagonisten |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US8008479B2 (de) |
| EP (1) | EP2010498B1 (de) |
| JP (1) | JP5208917B2 (de) |
| KR (1) | KR20080108291A (de) |
| AR (1) | AR060506A1 (de) |
| AT (1) | ATE486853T1 (de) |
| AU (1) | AU2007237482B2 (de) |
| CA (1) | CA2645362C (de) |
| CL (1) | CL2007001040A1 (de) |
| CY (1) | CY1111294T1 (de) |
| DE (1) | DE602007010269D1 (de) |
| DK (1) | DK2010498T3 (de) |
| EC (1) | ECSP088820A (de) |
| GT (1) | GT200800209A (de) |
| HK (1) | HK1125640A1 (de) |
| HR (1) | HRP20110045T1 (de) |
| JO (1) | JO2630B1 (de) |
| MA (1) | MA30394B1 (de) |
| MX (1) | MX2008013117A (de) |
| MY (1) | MY145069A (de) |
| NO (1) | NO20084783L (de) |
| NZ (1) | NZ571142A (de) |
| PE (1) | PE20071223A1 (de) |
| PL (1) | PL2010498T3 (de) |
| PT (1) | PT2010498E (de) |
| RU (1) | RU2433122C2 (de) |
| SI (1) | SI2010498T1 (de) |
| TW (1) | TW200815358A (de) |
| WO (1) | WO2007118651A1 (de) |
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| CA2583373C (en) | 2004-10-12 | 2013-09-03 | Fmc Biopolymer As | Self-gelling alginate systems and uses thereof |
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| US7820666B2 (en) | 2007-05-08 | 2010-10-26 | Concert Pharmaceuticals, Inc. | Tetrahydrotriazolopyrazine derivatives and uses thereof |
| RU2448958C2 (ru) | 2007-06-12 | 2012-04-27 | Консерт Фармасьютикалз, Инк. | Производные азапептидов |
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| EP2231155A4 (de) | 2007-12-18 | 2011-09-14 | Concert Pharmaceuticals Inc | Tetrahydroisochinolin-derivate |
| EP2242493B1 (de) | 2008-01-22 | 2013-06-05 | Concert Pharmaceuticals Inc. | Gefitinib-derivate |
| US8609673B2 (en) | 2008-01-22 | 2013-12-17 | Concert Pharmaceuticals, Inc. | Vandetanib derivatives |
| EP2265612B1 (de) | 2008-02-29 | 2017-04-05 | Concert Pharmaceuticals, Inc. | Substituierte xanthinderivate |
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| EP2334621A1 (de) | 2008-09-16 | 2011-06-22 | Concert Pharmaceuticals, Inc. | Deuterierte 2-amino-3-hydroxypropansäurederivate |
| EP2418211B1 (de) | 2008-09-19 | 2016-03-16 | Concert Pharmaceuticals Inc. | Deuterierte Morphinanverbindungen |
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| DE102010001040A1 (de) | 2010-01-20 | 2011-07-21 | Evonik RohMax Additives GmbH, 64293 | (Meth)acrylat-Polymere zur Verbesserung des Viskositätsindexes |
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| ES2804540T3 (es) | 2011-02-14 | 2021-02-08 | Concert Pharmaceuticals Inc | Análogos deuterados de ácido 4hidroxibutírico |
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| HUE047354T2 (hu) | 2011-05-18 | 2020-04-28 | Vertex Pharmaceuticals Europe Ltd | Ivacaftor deuterizált származékai |
| MX2014012384A (es) | 2012-04-13 | 2014-11-26 | Concert Pharmaceuticals Inc | Derivados sustituidos de xantina. |
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| IN2015DN00598A (de) | 2012-07-30 | 2015-06-26 | Concert Pharmaceuticals Inc | |
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| JP6526060B2 (ja) | 2014-02-10 | 2019-06-05 | コンサート ファーマシューティカルズ インコーポレイテッド | 置換トリアゾロベンゾジアゼピン |
| US10160778B2 (en) | 2014-10-27 | 2018-12-25 | Concert Pharmaceuticals, Inc. | Pyrimidine phosphonic acid esters |
| WO2016160945A1 (en) | 2015-03-31 | 2016-10-06 | Concert Pharmaceuticals, Inc. | Deuterated vx-661 |
| US10683305B2 (en) | 2015-04-27 | 2020-06-16 | Concert Pharmaceuticals, Inc. | Deuterated OTX-015 |
| MA42954A (fr) | 2015-09-25 | 2018-08-01 | Vertex Pharmaceuticals Europe Ltd | Potentialisateurs cftr deutérés |
| US11267777B2 (en) | 2015-11-19 | 2022-03-08 | Concert Pharmaceuticals, Inc. | Deuterated EPI-743 |
| US10442761B2 (en) | 2016-02-16 | 2019-10-15 | Concert Pharmaceuticals, Inc. | Deuterated GFT-505 |
| WO2019104179A1 (en) | 2017-11-22 | 2019-05-31 | Concert Pharmaceuticals, Inc. | Deuterated analogs of d-serine and uses thereof |
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Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA002348B1 (ru) | 1995-02-22 | 2002-04-25 | Новартис Аг | Соединения 1-арил-2-ациламиноэтана и их применение в качестве антагонистов нейрокинина, в частности нейрокинина 1 |
| MY132550A (en) * | 1996-08-22 | 2007-10-31 | Novartis Ag | Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists |
| GB0010958D0 (en) * | 2000-05-05 | 2000-06-28 | Novartis Ag | Organic compounds |
-
2007
- 2007-04-10 JO JO2007129A patent/JO2630B1/en active
- 2007-04-11 AU AU2007237482A patent/AU2007237482B2/en not_active Ceased
- 2007-04-11 WO PCT/EP2007/003213 patent/WO2007118651A1/en active Application Filing
- 2007-04-11 SI SI200730483T patent/SI2010498T1/sl unknown
- 2007-04-11 US US12/296,969 patent/US8008479B2/en not_active Expired - Fee Related
- 2007-04-11 NZ NZ571142A patent/NZ571142A/en not_active IP Right Cessation
- 2007-04-11 AR ARP070101533A patent/AR060506A1/es not_active Application Discontinuation
- 2007-04-11 PT PT07724154T patent/PT2010498E/pt unknown
- 2007-04-11 DE DE602007010269T patent/DE602007010269D1/de active Active
- 2007-04-11 RU RU2008145102/04A patent/RU2433122C2/ru not_active IP Right Cessation
- 2007-04-11 AT AT07724154T patent/ATE486853T1/de active
- 2007-04-11 PE PE2007000444A patent/PE20071223A1/es not_active Application Discontinuation
- 2007-04-11 PL PL07724154T patent/PL2010498T3/pl unknown
- 2007-04-11 DK DK07724154.5T patent/DK2010498T3/da active
- 2007-04-11 MX MX2008013117A patent/MX2008013117A/es active IP Right Grant
- 2007-04-11 CA CA2645362A patent/CA2645362C/en not_active Expired - Fee Related
- 2007-04-11 KR KR1020087024839A patent/KR20080108291A/ko not_active Application Discontinuation
- 2007-04-11 JP JP2009504637A patent/JP5208917B2/ja not_active Expired - Fee Related
- 2007-04-11 EP EP07724154A patent/EP2010498B1/de active Active
- 2007-04-12 TW TW096112886A patent/TW200815358A/zh unknown
- 2007-04-12 CL CL200701040A patent/CL2007001040A1/es unknown
-
2008
- 2008-10-08 MY MYPI20083997A patent/MY145069A/en unknown
- 2008-10-10 GT GT200800209A patent/GT200800209A/es unknown
- 2008-10-13 EC EC2008008820A patent/ECSP088820A/es unknown
- 2008-11-03 MA MA31347A patent/MA30394B1/fr unknown
- 2008-11-12 NO NO20084783A patent/NO20084783L/no not_active Application Discontinuation
-
2009
- 2009-05-15 HK HK09104457.9A patent/HK1125640A1/xx not_active IP Right Cessation
-
2011
- 2011-01-21 HR HR20110045T patent/HRP20110045T1/hr unknown
- 2011-01-26 CY CY20111100082T patent/CY1111294T1/el unknown
- 2011-07-22 US US13/188,795 patent/US20110282053A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |