KR20080077132A - 가변 부위에 글리코실화된, 아밀로이드 베타 4에 대한 항체 - Google Patents

가변 부위에 글리코실화된, 아밀로이드 베타 4에 대한 항체 Download PDF

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KR20080077132A
KR20080077132A KR1020087012289A KR20087012289A KR20080077132A KR 20080077132 A KR20080077132 A KR 20080077132A KR 1020087012289 A KR1020087012289 A KR 1020087012289A KR 20087012289 A KR20087012289 A KR 20087012289A KR 20080077132 A KR20080077132 A KR 20080077132A
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antibody
glycosylated
asn
antibody molecule
amyloid
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Korean (ko)
Inventor
한스루에디 로에트쉬에르
발테르 후베르
디아나 쉬우흐바우에르
카를 베예르
맨프레드 브로크하우스
베른드 보어만
한스 콜
안드레아스 쉬아우브마르
쿠르트 란그
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에프. 호프만-라 로슈 아게
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Publication of KR20080077132A publication Critical patent/KR20080077132A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020087012289A 2005-12-12 2006-12-11 가변 부위에 글리코실화된, 아밀로이드 베타 4에 대한 항체 Ceased KR20080077132A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05027090.9 2005-12-12
EP05027090 2005-12-12

Related Child Applications (1)

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KR1020127010552A Division KR101401159B1 (ko) 2005-12-12 2006-12-11 가변 부위에 글리코실화를 가지는 아밀로이드 베타에 대한 항체

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KR20080077132A true KR20080077132A (ko) 2008-08-21

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KR1020087012289A Ceased KR20080077132A (ko) 2005-12-12 2006-12-11 가변 부위에 글리코실화된, 아밀로이드 베타 4에 대한 항체
KR1020127010552A Active KR101401159B1 (ko) 2005-12-12 2006-12-11 가변 부위에 글리코실화를 가지는 아밀로이드 베타에 대한 항체

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US (2) US8906370B2 (https=)
EP (2) EP1960428B1 (https=)
JP (1) JP5145241B2 (https=)
KR (2) KR20080077132A (https=)
CN (2) CN102659943B (https=)
AR (1) AR057233A1 (https=)
AT (1) ATE517923T1 (https=)
AU (1) AU2006326301B2 (https=)
BR (1) BRPI0619605B8 (https=)
CA (1) CA2632828C (https=)
CR (1) CR10000A (https=)
CY (1) CY1114783T1 (https=)
DK (1) DK1960428T3 (https=)
DO (1) DOP2006000278A (https=)
EC (1) ECSP088524A (https=)
ES (1) ES2368591T3 (https=)
IL (1) IL191004A (https=)
JO (1) JO2824B1 (https=)
MA (1) MA30038B1 (https=)
MY (1) MY155286A (https=)
NO (1) NO346105B1 (https=)
NZ (1) NZ568241A (https=)
PE (3) PE20100684A1 (https=)
PL (1) PL1960428T3 (https=)
PT (1) PT1960428E (https=)
RS (1) RS52004B (https=)
RU (1) RU2438706C2 (https=)
SI (1) SI1960428T1 (https=)
TW (1) TWI382990B (https=)
UA (1) UA99097C2 (https=)
UY (1) UY30003A1 (https=)
WO (1) WO2007068429A1 (https=)
ZA (1) ZA200805038B (https=)

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