KR20080067357A - Ｉａｐ ｂｉｒ 도메인 결합 화합물 - Google Patents
Ｉａｐ ｂｉｒ 도메인 결합 화합물 Download PDFInfo
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- KR20080067357A KR20080067357A KR1020087012374A KR20087012374A KR20080067357A KR 20080067357 A KR20080067357 A KR 20080067357A KR 1020087012374 A KR1020087012374 A KR 1020087012374A KR 20087012374 A KR20087012374 A KR 20087012374A KR 20080067357 A KR20080067357 A KR 20080067357A
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| ATE477254T1 (de) | 2004-12-20 | 2010-08-15 | Genentech Inc | Pyrrolidine als inhibitoren von iap |
| EA012810B1 (ru) | 2005-02-25 | 2009-12-30 | Тетралоджик Фармасеутикалс | Димерные ингибиторы ингибиторов белков апоптоза (iap) |
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| US20100256046A1 (en) * | 2009-04-03 | 2010-10-07 | Tetralogic Pharmaceuticals Corporation | Treatment of proliferative disorders |
| KR20080067357A (ko) | 2005-10-25 | 2008-07-18 | 에게라 쎄라퓨틱스 인코포레이티드 | Ｉａｐ ｂｉｒ 도메인 결합 화합물 |
| RU2451025C2 (ru) | 2005-12-19 | 2012-05-20 | Дженентек, Инк. | Ингибиторы iap |
| TWI543988B (zh) | 2006-03-16 | 2016-08-01 | 科學製藥股份有限公司 | 結合於細胞凋亡抑制蛋白（ｉａｐ）之桿狀病毒ｉａｐ重複序列（ｂｉｒ）區域之化合物 |
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| MY159563A (en) * | 2006-05-16 | 2017-01-13 | Pharmascience Inc | Iap bir domain binding compounds |
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| AU2007276760B2 (en) * | 2006-07-24 | 2012-01-19 | Tetralogic Pharmaceuticals Corporation | Dimeric IAP antagonists |
| BRPI0809867A2 (pt) * | 2007-04-30 | 2014-09-30 | Genentech Inc | Composto, método de indução da apoptose em uma célula, método de sensibilização de uma célula para um sinal apoptótico, método para inibir a ligação de uma proteína iap a uma proteína caspase e métodos |
| US20110008802A1 (en) * | 2007-05-07 | 2011-01-13 | Tetralogic Pharmaceuticals Corp. | TNFalpha GENE EXPRESSION AS A BIOMARKER OF SENSITIVITY TO ANTAGONISTS OF INHIBITOR OF APOPTOSIS PROTEINS |
| US20100203012A1 (en) * | 2007-05-30 | 2010-08-12 | Aegera Therapeutics, Inc. | Iap bir domain binding compounds |
| US20120141496A1 (en) * | 2007-12-17 | 2012-06-07 | Aegera Therapeutics, Inc. | Iap bir domain binding compounds |
| EP2240506B1 (en) * | 2008-01-11 | 2012-12-26 | Genentech, Inc. | Inhibitors of iap |
| US20110117081A1 (en) * | 2008-05-05 | 2011-05-19 | Aegera Therapeutics, Inc. | Functionalized pyrrolidines and use thereof as iap inhibitors |
| US20110171171A1 (en) * | 2008-06-27 | 2011-07-14 | Aegera Therapeutics, Inc. | Bridged secondary amines and use thereof as iap bir domain binding compounds |
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| US8779280B2 (en) * | 2009-08-18 | 2014-07-15 | Lg Electronics Inc. | Solar cell and method of manufacturing the same |
| EP2784076A1 (en) | 2009-10-28 | 2014-10-01 | Joyant Pharmaceuticals, Inc. | Dimeric SMAC mimetics |
| KR20120140658A (ko) | 2010-02-12 | 2012-12-31 | 파마사이언스 인크. | Ｉａｐ ｂｉｒ 도메인 결합 화합물 |
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| NZ602392A (en) * | 2010-03-18 | 2014-03-28 | Innopharma Inc | Stable bortezomib formulations |
| UY33794A (es) | 2010-12-13 | 2012-07-31 | Novartis Ag | Inhibidores diméricos de las iap |
| JP2014528409A (ja) | 2011-09-30 | 2014-10-27 | テトラロジック ファーマシューティカルズ コーポレーション | 増殖性疾患（がん）の治療において使用するためのＳＭＡＣ模倣体（ビリナパント（ｂｉｒｉｎａｐａｎｔ）） |
| KR20200108903A (ko) | 2013-06-25 | 2020-09-21 | 더 월터 앤드 엘리자 홀 인스티튜트 오브 메디컬 리서치 | 세포내 감염의 치료 방법 |
| WO2015187998A2 (en) | 2014-06-04 | 2015-12-10 | Sanford-Burnham Medical Research Institute | Use of inhibitor of apoptosis protein (iap) antagonists in hiv therapy |
| WO2016079527A1 (en) | 2014-11-19 | 2016-05-26 | Tetralogic Birinapant Uk Ltd | Combination therapy |
| WO2016097773A1 (en) | 2014-12-19 | 2016-06-23 | Children's Cancer Institute | Therapeutic iap antagonists for treating proliferative disorders |
| EP3831811A4 (en) | 2018-07-31 | 2022-04-20 | Fimecs, Inc. | HETEROCYCLIC COMPOUND |
| JP7455141B2 (ja) * | 2019-04-05 | 2024-03-25 | へパジーン セラピューティクス （エイチケイ） リミテッド | アポトーシスタンパク質の阻害剤の二価拮抗薬 |
| WO2021020585A1 (ja) | 2019-07-31 | 2021-02-04 | ファイメクス株式会社 | 複素環化合物 |
| MX2022008874A (es) | 2020-01-20 | 2022-08-11 | Astrazeneca Ab | Inhibidores de la tirosina cinasa del receptor del factor de creciminto epidermico para el tratamiento del cancer. |
| CN119677743A (zh) * | 2023-02-08 | 2025-03-21 | 成都先导药物开发股份有限公司 | 杂环化合物及其用途 |
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-
2006
- 2006-10-20 KR KR1020087012374A patent/KR20080067357A/ko not_active Withdrawn
- 2006-10-20 US US11/583,816 patent/US7589118B2/en not_active Expired - Fee Related
- 2006-10-20 JP JP2008536890A patent/JP2009512719A/ja active Pending
- 2006-10-20 RU RU2008120408/04A patent/RU2418807C2/ru not_active IP Right Cessation
- 2006-10-20 CA CA2564872A patent/CA2564872C/en not_active Expired - Fee Related
- 2006-10-20 BR BRPI0617751-4A patent/BRPI0617751A2/pt not_active IP Right Cessation
- 2006-10-20 WO PCT/CA2006/001721 patent/WO2007048224A1/en not_active Ceased
- 2006-10-20 AU AU2006308453A patent/AU2006308453B9/en not_active Ceased
- 2006-10-20 EP EP06790872A patent/EP1951698A4/en not_active Withdrawn
- 2006-12-01 US US11/606,883 patent/US7547724B2/en not_active Expired - Fee Related
- 2006-12-04 US US11/607,998 patent/US7795298B2/en not_active Expired - Fee Related
- 2006-12-04 US US11/607,964 patent/US8063095B2/en not_active Expired - Fee Related
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2008
- 2008-04-17 IL IL190936A patent/IL190936A0/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240152498A (ko) * | 2023-04-13 | 2024-10-22 | 성신여자대학교 연구 산학협력단 | 비천연 아미노산을 포함하는 htra 표적 테트라펩타이드 프로브 |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008120408A (ru) | 2009-12-10 |
| BRPI0617751A2 (pt) | 2011-08-02 |
| JP2009512719A (ja) | 2009-03-26 |
| WO2007048224A1 (en) | 2007-05-03 |
| US7547724B2 (en) | 2009-06-16 |
| US20070093428A1 (en) | 2007-04-26 |
| AU2006308453B9 (en) | 2011-12-01 |
| EP1951698A4 (en) | 2010-04-28 |
| US7795298B2 (en) | 2010-09-14 |
| US20080014207A1 (en) | 2008-01-17 |
| CA2564872A1 (en) | 2007-04-25 |
| US20070093429A1 (en) | 2007-04-26 |
| AU2006308453A8 (en) | 2008-05-29 |
| US8063095B2 (en) | 2011-11-22 |
| AU2006308453A1 (en) | 2007-05-03 |
| RU2418807C2 (ru) | 2011-05-20 |
| AU2006308453B2 (en) | 2011-07-28 |
| IL190936A0 (en) | 2009-09-22 |
| CA2564872C (en) | 2010-12-21 |
| US7589118B2 (en) | 2009-09-15 |
| EP1951698A1 (en) | 2008-08-06 |
| US20070219140A1 (en) | 2007-09-20 |
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