KR20080007380A - 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 - Google Patents

지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 Download PDF

Info

Publication number
KR20080007380A
KR20080007380A KR1020077027301A KR20077027301A KR20080007380A KR 20080007380 A KR20080007380 A KR 20080007380A KR 1020077027301 A KR1020077027301 A KR 1020077027301A KR 20077027301 A KR20077027301 A KR 20077027301A KR 20080007380 A KR20080007380 A KR 20080007380A
Authority
KR
South Korea
Prior art keywords
peptide
self
composition
formulation
assembled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020077027301A
Other languages
English (en)
Korean (ko)
Inventor
루틀리지 엘리스-벤케
슈구앙 장
제랄드 슈나이더
궉-파이 소
데이비드 타이
유-시앙 리앙
Original Assignee
메사추세츠 인스티튜트 오브 테크놀로지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36939225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20080007380(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 메사추세츠 인스티튜트 오브 테크놀로지 filed Critical 메사추세츠 인스티튜트 오브 테크놀로지
Publication of KR20080007380A publication Critical patent/KR20080007380A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01GCOMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00Compounds of titanium
    • C01G23/04Oxides; Hydroxides
    • C01G23/047Titanium dioxide
    • C01G23/07Producing by vapour phase processes, e.g. halide oxidation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/06Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/08Heat treatment
    • B01J37/10Heat treatment in the presence of water, e.g. steam
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
KR1020077027301A 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법 Ceased KR20080007380A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67461205P 2005-04-25 2005-04-25
US60/674,612 2005-04-25
US75882706P 2006-01-13 2006-01-13
US60/758,827 2006-01-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020107019627A Division KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Publications (1)

Publication Number Publication Date
KR20080007380A true KR20080007380A (ko) 2008-01-18

Family

ID=36939225

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020077027301A Ceased KR20080007380A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법
KR1020107019627A Ceased KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020107019627A Ceased KR20100102750A (ko) 2005-04-25 2006-04-25 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법

Country Status (11)

Country Link
US (3) US9327010B2 (enExample)
EP (2) EP1879606B1 (enExample)
JP (3) JP5204646B2 (enExample)
KR (2) KR20080007380A (enExample)
CN (1) CN101267831B (enExample)
AU (1) AU2006241123B2 (enExample)
CA (1) CA2609656C (enExample)
DK (1) DK1879606T3 (enExample)
ES (1) ES2427565T3 (enExample)
IL (3) IL186779A (enExample)
WO (1) WO2006116524A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123375A1 (ko) * 2013-02-06 2014-08-14 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1843776A4 (en) * 2004-07-06 2011-05-11 3D Matrix Inc PURIFIED AMPHILIC PEPTIDE COMPOSITIONS AND ITS USE
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
KR20080007380A (ko) 2005-04-25 2008-01-18 메사추세츠 인스티튜트 오브 테크놀로지 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법
US9364412B2 (en) * 2005-11-14 2016-06-14 University Of Utah Research Foundation Electrostatically controlled hydrogels
AU2014203694B2 (en) * 2006-04-25 2016-08-11 Massachusetts Institute Of Technology Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
KR20110091019A (ko) * 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 오염물, 체액 또는 다른 실재물의 이동 및/또는 다른 생리학적 상태에 영향을 주기 위한 조성물 및 방법
JP5496671B2 (ja) 2006-09-26 2014-05-21 マサチューセッツ インスティテュート オブ テクノロジー 修飾自己組織化ペプチド
US7696309B2 (en) * 2006-10-23 2010-04-13 The Brigham And Women's Hospital, Inc. Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
WO2008073395A2 (en) * 2006-12-11 2008-06-19 3D Matrix, Inc. Compositions and methods for cardiac tissue protection and regeneration
EP2146733B1 (en) * 2007-03-14 2020-11-25 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
US20110022149A1 (en) 2007-06-04 2011-01-27 Cox Brian J Methods and devices for treatment of vascular defects
US7906478B2 (en) * 2007-07-20 2011-03-15 The Procter & Gamble Company Personal-care articles having self-assembling peptides
HUE043133T2 (hu) 2007-11-21 2019-07-29 Smith & Nephew Sebkötözés
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
ES2555204T3 (es) 2007-11-21 2015-12-29 T.J. Smith & Nephew Limited Dispositivo de succión y venda
ES2534770T3 (es) * 2007-12-05 2015-04-28 3-D Matrix, Ltd. Material para la curación de heridas y la reconstrucción de la piel
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
US20090169521A1 (en) * 2007-12-31 2009-07-02 Technion Research & Development Foundation Ltd. Vascularized cardiac tissue and methods of producing and using same
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
US8828358B2 (en) * 2008-03-11 2014-09-09 Materials Modifications, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide
US8852558B2 (en) * 2008-03-11 2014-10-07 Materials Modification, Inc. In situ formation of an artificial blockage to control bleeding by polymer expansion with hydrogen peroxide and platinum catalyst
US9629798B2 (en) * 2008-04-03 2017-04-25 Mallinckrodt Pharma Ip Trading D.A.C. Hemostatic microspheres
CN102119040A (zh) 2008-05-02 2011-07-06 斯昆特医疗公司 用于治疗血管缺损的丝状装置
CN101302249B (zh) * 2008-06-24 2011-08-17 四川大学 一种自组装短肽及其在制备抗肿瘤药物中的应用
ES2694000T3 (es) 2008-10-06 2018-12-17 3-D Matrix Ltd. Tapón de tejido
CN101514225B (zh) * 2008-10-13 2011-09-14 西安蓝晶生物科技有限公司 自聚体多肽及其制备方法和应用
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
US9333158B2 (en) 2009-03-16 2016-05-10 Nissan Chemical Industries, Ltd. Spray base material including low-molecular gelator
US20110054326A1 (en) * 2009-06-19 2011-03-03 Vanderbilt University Direct visualization catheter
US20110081398A1 (en) * 2009-10-01 2011-04-07 Tyco Healthcare Group Lp Multi-mechanism surgical compositions
CA2778639A1 (en) 2009-11-05 2011-05-12 Sequent Medical Inc. Multiple layer filamentary devices or treatment of vascular defects
US9439941B2 (en) 2009-12-14 2016-09-13 The University Of Hong Kong Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
US20110143993A1 (en) * 2009-12-15 2011-06-16 The Brigham And Women's Hospital, Inc. Endothelial basement membrane targeting peptide ligands
US9308277B2 (en) 2010-02-25 2016-04-12 Mesoblast International Sàrl Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
US8999916B2 (en) 2010-03-31 2015-04-07 Agency For Science, Technology And Research Crosslinked peptide hydrogels
US9687591B2 (en) 2010-03-31 2017-06-27 Agency For Science, Technology And Research Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes
WO2011123061A1 (en) 2010-03-31 2011-10-06 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
US8741833B2 (en) 2010-07-16 2014-06-03 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
CN107033596A (zh) 2010-11-25 2017-08-11 史密夫及内修公开有限公司 组合物i – ii及其产品和用途
US8546338B2 (en) 2010-12-08 2013-10-01 Johnson & Johnson Consumer Companies, Inc. Self-assembling hydrogels based on dicephalic peptide amphiphiles
JP6084352B2 (ja) * 2010-12-24 2017-02-22 国立大学法人 岡山大学 高強度ペプチドゲル
AU2012268078B2 (en) 2011-06-07 2017-06-01 Mesoblast International Sarl Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived Factor-1
EP2741788A4 (en) * 2011-08-14 2015-03-25 Materials Modification Inc METHOD AND COMPOSITION FOR IN-SITU FORMATION OF AN ARTIFICIAL BARRIER FOR FIGHTING BLOOD LOSS
WO2013030673A2 (en) * 2011-09-02 2013-03-07 3-D Matrix, Ltd. Amphiphilic peptides for thoracic air leakage occlusion
US11260072B2 (en) 2011-09-07 2022-03-01 3-D Matrix, Ltd. MicroRNA-based methods and assays for osteocarcinoma
US10905708B2 (en) 2011-09-07 2021-02-02 3-D Matrix, Ltd. MicroRNA-based methods and assays for osteocarcinoma
GB2496654A (en) * 2011-11-18 2013-05-22 Reckitt & Colman Overseas Self-assembling peptides
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
ES2706065T3 (es) 2012-07-06 2019-03-27 3 D Matrix Ltd Proceso de llenado-acabado para soluciones de péptidos
JP6183831B2 (ja) 2012-10-23 2017-08-23 義之 小山 ハイドロゲル形成材
US9241891B2 (en) 2012-10-30 2016-01-26 The Procter & Gamble Company Personal care compositions comprising self-assembling peptides
JP6376562B2 (ja) 2012-12-25 2018-08-22 扶桑薬品工業株式会社 止血剤アプリケータ
WO2014116187A1 (en) * 2013-01-28 2014-07-31 Agency For Science, Technology And Research Crosslinked peptide hydrogels
KR102045030B1 (ko) * 2013-02-08 2019-11-15 재단법인 아산사회복지재단 지혈요소가 구비된 의료기구
WO2014136081A1 (en) * 2013-03-06 2014-09-12 3D-Matrix Ltd. Surgical methods employing purified amphiphilic peptide compositions
EP2968654A1 (en) * 2013-03-14 2016-01-20 3-D Matrix, Ltd Treatment for bile leakage
JP6134050B2 (ja) 2013-03-14 2017-05-24 マサチューセッツ インスティテュート オブ テクノロジー ヒト抗体の長期間持続放出のための多層注射可能自己組織化ペプチドスキャホールドヒドロゲル
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
WO2014149617A1 (en) * 2013-03-15 2014-09-25 Cook Medical Technologies Llc Adhesive medical products and methods for treating gastrointestinal lesions
EP2968647B1 (en) 2013-03-15 2022-06-29 Smith & Nephew plc Wound dressing sealant and use thereof
JP6857857B2 (ja) * 2013-04-30 2021-04-14 国立大学法人九州工業大学 ペプチドおよびその自己集合方法、その集合体、これらを用いた細胞培養基材、並びに、細胞シートの製造方法
US10765774B2 (en) * 2013-07-09 2020-09-08 Ethicon, Inc. Hemostatic pad assembly kit and method
US9955976B2 (en) 2013-08-16 2018-05-01 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
US9078658B2 (en) 2013-08-16 2015-07-14 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
DK3035974T3 (da) * 2013-08-22 2020-01-02 Arch Biosurgery Inc Implanterbare net til styring af bevægelsen af fluider
CN103656618B (zh) * 2013-10-25 2016-06-08 广东药学院 治疗皮肤创伤的多肽纳米纤维凝胶制剂、制备方法及应用
CN103665110B (zh) * 2013-12-06 2015-10-28 华南理工大学 半程电荷互补型手性自组装短肽纳米生物医药材料及应用
JP2015142720A (ja) * 2013-12-27 2015-08-06 株式会社メニコン 止血材
JP6490897B2 (ja) * 2013-12-27 2019-03-27 株式会社メニコンネクト 自己組織化ペプチドゲル
JP6684719B2 (ja) 2014-03-10 2020-04-22 株式会社スリー・ディー・マトリックス ペプチド組成物の滅菌および濾過
BR112016020584A2 (pt) 2014-03-10 2017-10-03 3 D Matrix Ltd Composições de peptídeo auto-organizável
ES2712608T3 (es) 2014-03-10 2019-05-14 3 D Matrix Ltd Péptidos autoensamblantes para el tratamiento de las bullas pulmonares
KR20160142843A (ko) * 2014-03-28 2016-12-13 오츠카 가가쿠 가부시키가이샤 지혈용 약학 조성물
US9629635B2 (en) 2014-04-14 2017-04-25 Sequent Medical, Inc. Devices for therapeutic vascular procedures
WO2016006693A1 (ja) * 2014-07-11 2016-01-14 株式会社メニコン 視認性確保材および視認性確保材吐出装置
DE102015000363A1 (de) 2015-01-20 2016-07-21 Emc Microcollections Gmbh Neue modular funktionalisierbare Peptid-Hydrogele
EP3391897B1 (en) * 2015-12-18 2021-09-08 3-D Matrix Ltd. Hemostatic composition and hemostatic method using hemostatic composition
US10814038B2 (en) 2016-01-06 2020-10-27 3-D Matrix, Ltd. Combination compositions
WO2017158435A1 (en) * 2016-03-18 2017-09-21 3-D Matrix, Ltd. Cerebrospinal fluid leakage occlusion
KR20190022455A (ko) * 2016-03-18 2019-03-06 가부시끼가이샤 쓰리디 매트릭스 생물학적 조직 유착을 방지하는 방법
BR112018068838A2 (pt) * 2016-03-18 2019-01-22 3 D Matrix Ltd oclusão de fístula pancreática
WO2017210416A1 (en) * 2016-06-01 2017-12-07 3-D Matrix, Ltd. Hemostatic dressings with self-assembling peptide hydrogels
US20190275196A1 (en) * 2016-06-01 2019-09-12 Eun Seok Gil Hemostatic Powders with Self-Assembling Peptide Hydrogels
JP6912953B2 (ja) * 2016-06-27 2021-08-04 三洋化成工業株式会社 体液漏出防止剤
JP7012950B2 (ja) 2016-11-17 2022-01-31 地方独立行政法人東京都立産業技術研究センター 生体組織孔閉鎖用、潰瘍保護用及び血管塞栓療術用ゾル
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
CN106701724B (zh) * 2016-12-27 2019-10-08 江南大学 一种碱性果胶酶活性包涵体的制备及其应用
CN107529533B (zh) * 2017-09-07 2020-10-30 中国药科大学 一类可自组装成水凝胶的pH敏感多肽及其作为装载药物材料的应用
KR101989054B1 (ko) * 2017-11-28 2019-06-13 (주)다림티센 지혈용 조성물 및 이를 포함하는 용기
CN107802883B (zh) * 2017-12-09 2020-08-14 青岛市妇女儿童医院 一种伤口清洗液
EP3723726A1 (en) 2017-12-15 2020-10-21 3-D Matrix, Ltd. Surfactant peptide nanostructures and uses in drug delivery
WO2019182905A1 (en) * 2018-03-23 2019-09-26 Arch Biosurgery, Inc. Sap and peptidomimetics for treatment of eye disease
EP3768295A1 (en) 2018-03-23 2021-01-27 Arch Biosurgery, Inc. Sap and peptidomimetic compositions for reducing symptoms of inflammation
CN108517006B (zh) * 2018-05-10 2021-05-28 暨南大学 一种常温常压条件下改善碳纳米管在水中分散性的多肽材料及其应用
JP7142286B2 (ja) * 2018-07-13 2022-09-27 慶應義塾 セレン含有アミノ酸を含む糖鎖-ポリペプチド複合体、および、その医薬用途
CN113194976A (zh) * 2018-10-05 2021-07-30 学校法人久留米大学 用于肠道中的溃疡或瘘管的治疗或预防的医药组合物
MX2021003930A (es) * 2018-10-05 2021-06-04 Basf Se Compuestos estabilizadores de hidrolasas en liquidos.
CN109136165A (zh) * 2018-10-16 2019-01-04 罗忠礼 一种自组装短肽在皮肤组织创伤中快速修复的应用
CN109646711A (zh) * 2019-01-29 2019-04-19 青岛中腾生物技术有限公司 一种医用止血封闭防黏连材料
JP7483744B2 (ja) 2019-03-15 2024-05-15 マイクロベンション インコーポレイテッド 血管障害の治療のためのフィラメント状デバイス
CN113573650B (zh) 2019-03-15 2024-05-28 后续医疗股份有限公司 用于治疗血管缺陷的具有柔性连接部的丝装置
WO2020190620A1 (en) 2019-03-15 2020-09-24 Sequent Medical, Inc. Filamentary devices for treatment of vascular defects
CN110256572B (zh) * 2019-05-07 2022-11-01 西北大学 一种rhc-(rada)4融合蛋白
AU2020292274B2 (en) 2019-06-13 2024-05-23 Hollister Incorporated Reusable urinary catheter products
CA3140908A1 (en) 2019-06-25 2020-12-30 Hollister Incorporated Reusable urinary catheter products
CN110396124B (zh) * 2019-08-21 2021-04-13 上海交通大学 自组装多肽及其作为止血剂的用途
WO2021146291A1 (en) 2020-01-13 2021-07-22 Arch Biosurgery, Inc. Self-assembling peptide gel formulation and methods of use
US12023034B2 (en) 2020-03-11 2024-07-02 Microvention, Inc. Devices for treatment of vascular defects
US20210282789A1 (en) 2020-03-11 2021-09-16 Microvention, Inc. Multiple layer devices for treatment of vascular defects
US12070220B2 (en) 2020-03-11 2024-08-27 Microvention, Inc. Devices having multiple permeable shells for treatment of vascular defects
CN111848736B (zh) * 2020-08-05 2021-12-31 赛克赛斯生物科技股份有限公司 自组装多肽、制备方法、自组装多肽制剂及应用
CN112386737B (zh) * 2020-11-23 2022-07-26 上海交通大学 一种限制伤口部位的体液溢出的组合物
CN113046884B (zh) * 2021-03-25 2022-06-10 台州市中心医院(台州学院附属医院) 一种抗菌可降解医用缝合线
US12446891B2 (en) 2021-08-30 2025-10-21 Microvention, Inc. Devices for treatment of vascular defects
CN114230640A (zh) * 2021-12-21 2022-03-25 西安交通大学 一种具有自组装能力的氨基酸缩合物
EP4518977A1 (en) * 2022-05-04 2025-03-12 Massachusetts Institute Of Technology Formulations and medical devices for minimally-invasive deep tissue applications
CN115252810B (zh) * 2022-05-26 2025-06-27 安徽中医药大学 一种可变形态的喜树碱多肽纳米制剂及其制备方法和应用

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1006606A (en) 1961-05-12 1965-10-06 Fmc Corp Haemostatic wound dressing
US4098728A (en) * 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4272398A (en) * 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4636208A (en) * 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US5019646A (en) 1987-08-25 1991-05-28 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5843156A (en) 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
US5126141A (en) * 1988-11-16 1992-06-30 Mediventures Incorporated Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
CA2122041A1 (en) 1989-12-04 1993-04-29 Kenneth Kensey Plug device for sealing openings and method of use
US5180375A (en) 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US5222974A (en) * 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
JPH05204646A (ja) 1992-01-28 1993-08-13 Mitsubishi Electric Corp 知識処理システム
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5955343A (en) * 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
FR2715309B1 (fr) 1994-01-24 1996-08-02 Imedex Composition adhésive, à usage chirurgical, à base de collagène modifié par coupure oxydative et non réticulé.
US6413539B1 (en) 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
AU5638096A (en) 1995-06-07 1996-12-30 Clarion Pharmaceuticals, Inc. Non-biological patch for hemostasis
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
CA2251475C (en) 1996-04-04 2006-09-05 Immuno Aktiengesellschaft Hemostatic sponge based on collagen
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
US6177609B1 (en) 1997-03-10 2001-01-23 Meadox Medicals, Inc. Self-aggregating protein compositions and use as sealants
US5906997A (en) 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US6368877B1 (en) * 1997-06-25 2002-04-09 Massachusetts Institute Of Technology Self-assembling peptide surfaces for cell patterning and interactions
WO1999052574A1 (en) 1998-04-10 1999-10-21 Massachusetts Institute Of Technology Biopolymers resistant coatings
JP4159682B2 (ja) 1998-12-22 2008-10-01 株式会社クラレ 止血材
AU3347000A (en) * 1999-01-19 2000-08-01 Children's Hospital Of Philadelphia, The Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
WO2000063079A1 (en) * 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
JP4596341B2 (ja) 1999-11-11 2010-12-08 オリンパステルモバイオマテリアル株式会社 液体状創傷被覆材
US6844324B1 (en) * 1999-11-12 2005-01-18 Massachusetts Institute Of Technology Modular peptide mediated intracellular delivery system and uses therefore
DE60118527D1 (de) * 2000-01-24 2006-05-18 Compound Therapeutics Inc Sensible und multiplexe diagnostische tests zur proteinanalyse
US20020010150A1 (en) 2000-04-28 2002-01-24 Cortese Stephanie M. Homostatic compositions of polyacids and polyalkylene oxides and methods for their use
US6953656B2 (en) * 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of polypeptides
US6953659B2 (en) * 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of nucleic acids
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
PL206197B1 (pl) 2001-01-25 2010-07-30 Nycomed Pharma Asnycomed Pharma As Sposób wytwarzania gąbki kolagenowej
US7449180B2 (en) * 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
DE60230593D1 (de) 2001-02-06 2009-02-12 Massachusetts Inst Technology Peptidgerüstverkapselung von gewebszellen und verwendungen davon
JP3838882B2 (ja) 2001-02-28 2006-10-25 株式会社Phg 温度応答性材料およびそれを含む組成物
CA2446322A1 (en) 2001-05-04 2002-11-14 M. Reza Ghadiri Anti-microbial peptides and compositions
AU2002350088A1 (en) 2001-06-22 2003-01-08 Millard Marsden Mershon Compositions and methods for reducing blood and fluid loss from open wounds
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
US20060199778A1 (en) * 2001-09-19 2006-09-07 Rutledge Ellis-Behnke Methods and products related to non-viral transfection
JP2003252936A (ja) 2002-02-28 2003-09-10 Sentomedo:Kk 温度応答性材料及びそれを含む組成物
WO2003084980A2 (en) 2002-04-02 2003-10-16 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
AU2003249606A1 (en) 2002-05-13 2003-12-02 Massachusetts Institute Of Technology Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof
CA2387257C (en) * 2002-05-23 2009-07-28 Suncor Energy Inc. Static deaeration conditioner for processing of bitumen froth
GB0216286D0 (en) 2002-07-15 2002-08-21 Univ Leeds Network
AU2003261398A1 (en) * 2002-08-06 2004-02-23 Epix Pharmaceuticals, Inc. Peptide aggregates
WO2004110964A2 (en) 2003-06-16 2004-12-23 Nuevolution A/S Encoded molecules by translation (emt)
US7713923B2 (en) * 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
WO2005014615A2 (en) * 2003-06-25 2005-02-17 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
ES2552226T3 (es) * 2003-06-27 2015-11-26 DePuy Synthes Products, Inc. Reparación y regeneración de cartílago y hueso utilizando células derivadas posparto
JP2005074079A (ja) 2003-09-02 2005-03-24 Masao Tanihara 止血材
US7846891B2 (en) * 2003-10-17 2010-12-07 Massachusetts Institute Of Technology Self-assembling peptides for regeneration and repair of neural tissue
US20050266086A1 (en) * 2004-06-01 2005-12-01 Sawhney Amarpreet S Intrauterine applications of materials formed in situ
EP1843776A4 (en) 2004-07-06 2011-05-11 3D Matrix Inc PURIFIED AMPHILIC PEPTIDE COMPOSITIONS AND ITS USE
US7884185B2 (en) * 2004-07-28 2011-02-08 University Of Delaware Hydrogels and uses thereof
US8039258B2 (en) 2004-09-28 2011-10-18 Ethicon, Inc. Tissue-engineering scaffolds containing self-assembled-peptide hydrogels
WO2006047315A2 (en) * 2004-10-25 2006-05-04 The Brigham And Women's Hospital, Inc. Targeted delivery of biological factors using self-assembling peptide nanofibers
JP2008526749A (ja) * 2005-01-04 2008-07-24 ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド 自己アセンブリするペプチドナノファイバーを用いたpdgfの徐放性の送達
US9162005B2 (en) * 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
KR20080007380A (ko) * 2005-04-25 2008-01-18 메사추세츠 인스티튜트 오브 테크놀로지 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및방법
KR20110091019A (ko) * 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 오염물, 체액 또는 다른 실재물의 이동 및/또는 다른 생리학적 상태에 영향을 주기 위한 조성물 및 방법
WO2007147002A2 (en) 2006-06-13 2007-12-21 Wisconsin Alumni Research Foundation Beta-peptide lyotropic liquid crystals and methods of manufacture and use thereof
JP5496671B2 (ja) * 2006-09-26 2014-05-21 マサチューセッツ インスティテュート オブ テクノロジー 修飾自己組織化ペプチド
EP2146733B1 (en) 2007-03-14 2020-11-25 Arch Biosurgery, Inc. Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
US20120085262A1 (en) 2010-08-26 2012-04-12 Freudenberg Forschungsdienste Kg Production of Highly Concentrated Solutions of Self-Assembling Proteins
EP3597209A1 (en) 2012-02-22 2020-01-22 Northwestern University Nanostructures for treating cancers and other conditions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014123375A1 (ko) * 2013-02-06 2014-08-14 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도
KR101432276B1 (ko) * 2013-02-06 2014-08-21 주식회사 이노테라피 총경동맥 또는 상시상 정맥동에 출혈이 유발된 지혈제 성능평가 동물모델 및 그 용도

Also Published As

Publication number Publication date
JP5629241B2 (ja) 2014-11-19
EP2283851B1 (en) 2023-06-07
US20090111734A1 (en) 2009-04-30
IL250767A0 (en) 2017-04-30
AU2006241123B2 (en) 2013-10-03
CA2609656C (en) 2016-02-02
JP5204646B2 (ja) 2013-06-05
IL250767B (en) 2019-02-28
US9327010B2 (en) 2016-05-03
IL245530A (en) 2017-03-30
US11839694B2 (en) 2023-12-12
WO2006116524A1 (en) 2006-11-02
AU2006241123A1 (en) 2006-11-02
KR20100102750A (ko) 2010-09-24
JP2011168623A (ja) 2011-09-01
ES2427565T3 (es) 2013-10-31
US20160296660A1 (en) 2016-10-13
IL186779A0 (en) 2008-03-20
EP1879606B1 (en) 2013-06-12
IL245530A0 (en) 2016-06-30
JP2014221830A (ja) 2014-11-27
IL186779A (en) 2016-05-31
US20070203062A1 (en) 2007-08-30
EP2283851A2 (en) 2011-02-16
CA2609656A1 (en) 2006-11-02
CN101267831B (zh) 2013-04-24
EP1879606A1 (en) 2008-01-23
DK1879606T3 (da) 2013-09-23
EP2283851A3 (en) 2011-06-08
JP2008539257A (ja) 2008-11-13
US9364513B2 (en) 2016-06-14
HK1112847A1 (en) 2008-09-19
CN101267831A (zh) 2008-09-17

Similar Documents

Publication Publication Date Title
JP5629241B2 (ja) 止血および他の生理学的活性を促進するための組成物および方法
US10682386B2 (en) Compositions for prevention of adhesions and other barrier applications
US10137166B2 (en) Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or affecting other physiological conditions
AU2014203694A1 (en) Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
HK1112847B (en) Self-assembling peptides for promoting hemostasis
HK1155356A (en) Compositions and methods for promoting hemostasis and other physiological activities
HK1132469A (en) Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
HK1184397B (en) Compositions for prevention of adhesions and other barrier applications

Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

Patent event date: 20071123

Patent event code: PA01051R01D

Comment text: International Patent Application

PA0201 Request for examination
PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20090824

Patent event code: PE09021S01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20100302

Patent event code: PE09021S01D

A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20100902

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20110129

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20100302

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

Patent event date: 20090824

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20110502

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20110129

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20120704

Appeal identifier: 2011101003208

Request date: 20110502

J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20110502

Effective date: 20120704

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20120704

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 20110502

Decision date: 20120704

Appeal identifier: 2011101003208

J121 Written withdrawal of request for trial
PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20120828

PJ1201 Withdrawal of trial

Patent event code: PJ12011R01D

Patent event date: 20120828

Comment text: Written Withdrawal of Request for Trial

Appeal identifier: 2011101003208

Request date: 20110502

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20120704

WITB Written withdrawal of application