BR112016020584A2 - Composições de peptídeo auto-organizável - Google Patents

Composições de peptídeo auto-organizável

Info

Publication number
BR112016020584A2
BR112016020584A2 BR112016020584A BR112016020584A BR112016020584A2 BR 112016020584 A2 BR112016020584 A2 BR 112016020584A2 BR 112016020584 A BR112016020584 A BR 112016020584A BR 112016020584 A BR112016020584 A BR 112016020584A BR 112016020584 A2 BR112016020584 A2 BR 112016020584A2
Authority
BR
Brazil
Prior art keywords
peptide
self
peptide compositions
organizable
concentration
Prior art date
Application number
BR112016020584A
Other languages
English (en)
Inventor
Seok Gil Eun
Gilbert Karl
Mehta Manav
Original Assignee
3 D Matrix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 D Matrix Ltd filed Critical 3 D Matrix Ltd
Publication of BR112016020584A2 publication Critical patent/BR112016020584A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/108—Specific proteins or polypeptides not covered by groups A61L24/102 - A61L24/106
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

COMPOSIÇÕES DE PEPTÍDEO AUTO-ORGANIZÁVEL. A presente revelação fornece composições peptídicas (por exemplo, de peptídeos auto-organizáveis) com a tributos particulares (por exemplo, identidade do peptídeo, concentração de peptídeo, pH, força iônica [incluindo identidade e/ou concentração do sal) etc. que mostram propriedades materiais particularmente úteis. A presente revelação também fornece tecnologias para a seleção e/ou formulação de composições peptídicas particulares úteis em contextos específicos. Em algumas modalidades, as composições peptídicas fornecidas possuem um pH elevado dentro da faixa de cerca de 2,5 até cerca de 3,5 e/ ou uma força iônica que é acima daquela de uma composição correspondente do mesmo peptídeo, na mesma concentração, em água, mas é abaixo de um ponto de sal crítico para o peptídeo (por exemplo, de modo que a composição não seja turva).
BR112016020584A 2014-03-10 2015-03-10 Composições de peptídeo auto-organizável BR112016020584A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461950529P 2014-03-10 2014-03-10
PCT/US2015/019796 WO2015138514A1 (en) 2014-03-10 2015-03-10 Self-assembling peptide compositions

Publications (1)

Publication Number Publication Date
BR112016020584A2 true BR112016020584A2 (pt) 2017-10-03

Family

ID=53008839

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016020584A BR112016020584A2 (pt) 2014-03-10 2015-03-10 Composições de peptídeo auto-organizável

Country Status (12)

Country Link
US (3) US10654893B2 (pt)
EP (2) EP3116896B1 (pt)
JP (3) JP6628733B2 (pt)
KR (1) KR20160127827A (pt)
CN (2) CN106459154A (pt)
AU (2) AU2015229549B2 (pt)
BR (1) BR112016020584A2 (pt)
CA (1) CA2939696C (pt)
DK (1) DK3116896T3 (pt)
ES (1) ES2711728T3 (pt)
RU (1) RU2016139369A (pt)
WO (1) WO2015138514A1 (pt)

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CA2939696C (en) 2023-01-10
DK3116896T3 (en) 2019-03-18
EP3116896B1 (en) 2018-12-19
CN106459154A (zh) 2017-02-22
ES2711728T3 (es) 2019-05-07
KR20160127827A (ko) 2016-11-04
JP2020055836A (ja) 2020-04-09
JP2022036947A (ja) 2022-03-08
AU2019219809A1 (en) 2019-09-12
JP7397042B2 (ja) 2023-12-12
WO2015138514A1 (en) 2015-09-17
US10654893B2 (en) 2020-05-19
CA2939696A1 (en) 2015-09-17
JP2017510568A (ja) 2017-04-13
AU2015229549B2 (en) 2019-05-23
EP3466965A1 (en) 2019-04-10
US20160362451A1 (en) 2016-12-15
EP3116896A1 (en) 2017-01-18
JP6628733B2 (ja) 2020-01-15
RU2016139369A (ru) 2018-04-10
US20220033442A1 (en) 2022-02-03
CN117138022A (zh) 2023-12-01
US20200399310A1 (en) 2020-12-24
AU2015229549A1 (en) 2016-08-18

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