KR20070083654A - 맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 - Google Patents
맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 Download PDFInfo
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- KR20070083654A KR20070083654A KR1020077008212A KR20077008212A KR20070083654A KR 20070083654 A KR20070083654 A KR 20070083654A KR 1020077008212 A KR1020077008212 A KR 1020077008212A KR 20077008212 A KR20077008212 A KR 20077008212A KR 20070083654 A KR20070083654 A KR 20070083654A
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- rapamycin
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9606452.2 | 1996-03-27 | ||
| GBGB9606452.2A GB9606452D0 (en) | 1996-03-27 | 1996-03-27 | Organic compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057005463A Division KR100836971B1 (ko) | 1996-03-27 | 1997-03-26 | 맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20070083654A true KR20070083654A (ko) | 2007-08-24 |
Family
ID=10791127
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077008212A Withdrawn KR20070083654A (ko) | 1996-03-27 | 1997-03-26 | 맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 |
| KR1020057005463A Expired - Lifetime KR100836971B1 (ko) | 1996-03-27 | 1997-03-26 | 맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057005463A Expired - Lifetime KR100836971B1 (ko) | 1996-03-27 | 1997-03-26 | 맥관 장애 및 이종 이식술에서의 라파마이신 유도체의 용도 |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US6384046B1 (https=) |
| EP (3) | EP2008657B1 (https=) |
| JP (2) | JP2000507226A (https=) |
| KR (2) | KR20070083654A (https=) |
| CN (1) | CN1124135C (https=) |
| AT (1) | ATE224194T1 (https=) |
| AU (1) | AU716514B2 (https=) |
| BR (1) | BR9708358A (https=) |
| CA (1) | CA2247275C (https=) |
| CY (1) | CY2404B1 (https=) |
| CZ (1) | CZ292483B6 (https=) |
| DE (1) | DE69715611T2 (https=) |
| DK (2) | DK2008657T3 (https=) |
| ES (2) | ES2184078T3 (https=) |
| GB (1) | GB9606452D0 (https=) |
| HU (1) | HU226422B1 (https=) |
| ID (1) | ID17195A (https=) |
| IL (1) | IL125812A (https=) |
| MY (1) | MY117798A (https=) |
| NO (1) | NO316667B1 (https=) |
| NZ (1) | NZ331463A (https=) |
| PL (1) | PL187732B1 (https=) |
| PT (2) | PT2008657E (https=) |
| RU (1) | RU2214247C2 (https=) |
| SI (1) | SI2008657T1 (https=) |
| SK (1) | SK284343B6 (https=) |
| TR (1) | TR199801919T2 (https=) |
| WO (1) | WO1997035575A1 (https=) |
| ZA (1) | ZA972719B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
| PT956034E (pt) | 1996-07-30 | 2002-12-31 | Novartis Ag | Composicoes farmaceuticas para o tratamento da rejeicao de transplantes estados inflamatorios ou auto-imunes compreendendo ciclosporina a e 40-o-(2-hidroxietil)-rapamicina |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| US6890546B2 (en) | 1998-09-24 | 2005-05-10 | Abbott Laboratories | Medical devices containing rapamycin analogs |
| DE60044717D1 (de) * | 1999-05-10 | 2010-09-02 | Paolo Brenner | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
| US20070032853A1 (en) † | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
| US7807211B2 (en) | 1999-09-03 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of an implantable medical device |
| US6790228B2 (en) | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US20070141107A1 (en) * | 2000-03-15 | 2007-06-21 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
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| US20030229393A1 (en) * | 2001-03-15 | 2003-12-11 | Kutryk Michael J. B. | Medical device with coating that promotes cell adherence and differentiation |
| US8460367B2 (en) * | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| AU2001245734A1 (en) | 2000-03-15 | 2001-09-24 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
| US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
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| CN1655738A (zh) * | 2002-05-20 | 2005-08-17 | 奥勃斯医学技术股份有限公司 | 可植入的药物洗脱医疗装置 |
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| CN102268015B (zh) * | 2011-08-30 | 2013-08-28 | 成都摩尔生物医药有限公司 | 一种依维莫司的合成方法 |
| US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
| KR101723265B1 (ko) | 2013-08-16 | 2017-04-04 | 가톨릭대학교 산학협력단 | mTOR/STAT3 신호억제제 처리된 면역조절능을 갖는 간엽줄기세포 및 이를 포함하는 면역질환의 예방 또는 치료용 세포치료제 조성물 |
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| CN110831656A (zh) | 2017-05-04 | 2020-02-21 | 吉纳生命科学公司 | 稳健的可植入气体递送装置和方法、系统以及包括该装置的装置 |
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| HRP20250197T1 (hr) | 2018-12-18 | 2025-04-11 | Novartis Ag | Derivati rapamicina |
| US20200261427A1 (en) | 2019-02-20 | 2020-08-20 | Al Therapeutics, Inc. | Topical rapamycin formulations and their use in treating facial angiofibromas and other skin disorders |
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| US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
| US5364612A (en) * | 1991-05-06 | 1994-11-15 | Immunomedics, Inc. | Detection of cardiovascular lesions |
| ZA924953B (en) * | 1991-07-25 | 1993-04-28 | Univ Louisville Res Found | Method of treating ocular inflammation |
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| US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
| CA2094858C (en) * | 1992-04-28 | 2004-06-15 | Robert D. Mitchell | Method of treating hyperproliferative vascular disease |
| US5747034A (en) * | 1992-07-09 | 1998-05-05 | Chiron Corporation | Methods and materials for the induction of T cell anergy |
| US5283257A (en) * | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| SK78196A3 (en) * | 1993-12-17 | 1997-02-05 | Sandoz Ag | Rapamycin demethoxy-derivatives, preparation method thereof and pharmaceutical agent containing them |
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| GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
-
1996
- 1996-03-27 GB GBGB9606452.2A patent/GB9606452D0/en active Pending
-
1997
- 1997-03-25 MY MYPI97001258A patent/MY117798A/en unknown
- 1997-03-25 ID IDP970980A patent/ID17195A/id unknown
- 1997-03-26 TR TR1998/01919T patent/TR199801919T2/xx unknown
- 1997-03-26 CZ CZ19983070A patent/CZ292483B6/cs not_active IP Right Cessation
- 1997-03-26 PT PT80173362T patent/PT2008657E/pt unknown
- 1997-03-26 EP EP08017336.2A patent/EP2008657B1/en not_active Expired - Lifetime
- 1997-03-26 BR BR9708358A patent/BR9708358A/pt not_active Application Discontinuation
- 1997-03-26 WO PCT/EP1997/001548 patent/WO1997035575A1/en not_active Ceased
- 1997-03-26 IL IL12581297A patent/IL125812A/en not_active IP Right Cessation
- 1997-03-26 ES ES97915441T patent/ES2184078T3/es not_active Expired - Lifetime
- 1997-03-26 KR KR1020077008212A patent/KR20070083654A/ko not_active Withdrawn
- 1997-03-26 PL PL97328659A patent/PL187732B1/pl unknown
- 1997-03-26 HU HU0001267A patent/HU226422B1/hu unknown
- 1997-03-26 DK DK08017336.2T patent/DK2008657T3/da active
- 1997-03-26 DK DK97915441T patent/DK0893996T3/da active
- 1997-03-26 AU AU22918/97A patent/AU716514B2/en not_active Expired
- 1997-03-26 NZ NZ331463A patent/NZ331463A/en not_active IP Right Cessation
- 1997-03-26 JP JP9532077A patent/JP2000507226A/ja not_active Withdrawn
- 1997-03-26 CN CN97193278A patent/CN1124135C/zh not_active Expired - Lifetime
- 1997-03-26 SI SI9730801T patent/SI2008657T1/sl unknown
- 1997-03-26 ES ES08017336T patent/ES2421455T3/es not_active Expired - Lifetime
- 1997-03-26 SK SK1327-98A patent/SK284343B6/sk not_active IP Right Cessation
- 1997-03-26 AT AT97915441T patent/ATE224194T1/de not_active IP Right Cessation
- 1997-03-26 DE DE69715611T patent/DE69715611T2/de not_active Revoked
- 1997-03-26 CA CA2247275A patent/CA2247275C/en not_active Expired - Lifetime
- 1997-03-26 EP EP01116262A patent/EP1149581A3/en not_active Withdrawn
- 1997-03-26 PT PT97915441T patent/PT893996E/pt unknown
- 1997-03-26 KR KR1020057005463A patent/KR100836971B1/ko not_active Expired - Lifetime
- 1997-03-26 EP EP97915441A patent/EP0893996B1/en not_active Revoked
- 1997-03-26 RU RU98119312/14A patent/RU2214247C2/ru active
- 1997-03-27 ZA ZA972719A patent/ZA972719B/xx unknown
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1998
- 1998-09-18 NO NO19984340A patent/NO316667B1/no not_active IP Right Cessation
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2000
- 2000-11-14 US US09/712,359 patent/US6384046B1/en not_active Expired - Lifetime
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2002
- 2002-03-07 US US10/092,639 patent/US20020127248A1/en not_active Abandoned
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2004
- 2004-01-08 CY CY0400004A patent/CY2404B1/xx unknown
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2008
- 2008-12-10 JP JP2008314494A patent/JP5124431B2/ja not_active Expired - Lifetime
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2010
- 2010-03-01 US US12/715,007 patent/US20100152105A1/en not_active Abandoned
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2012
- 2012-01-24 US US13/357,199 patent/US20120177690A1/en not_active Abandoned
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2014
- 2014-03-05 US US14/197,368 patent/US20140187574A1/en not_active Abandoned
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