KR20070045153A - 의약용 씨알티에이치2 수용체 리간드 - Google Patents

의약용 씨알티에이치2 수용체 리간드 Download PDF

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KR20070045153A
KR20070045153A KR1020067027504A KR20067027504A KR20070045153A KR 20070045153 A KR20070045153 A KR 20070045153A KR 1020067027504 A KR1020067027504 A KR 1020067027504A KR 20067027504 A KR20067027504 A KR 20067027504A KR 20070045153 A KR20070045153 A KR 20070045153A
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South Korea
Prior art keywords
bromo
phenoxy
carbonyl
pyrazole
acetic acid
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Ceased
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KR1020067027504A
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English (en)
Korean (ko)
Inventor
트론드 울벤
토마스 프리무러
오이스테인 리스트
에비 코스테니스
토마스 훼그버그
진-마리에 리세베우르
마리에 그림스트루프
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7티엠 파마 에이/에스
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Priority claimed from GB0412198A external-priority patent/GB0412198D0/en
Priority claimed from GB0414196A external-priority patent/GB0414196D0/en
Priority claimed from GB0424018A external-priority patent/GB0424018D0/en
Application filed by 7티엠 파마 에이/에스 filed Critical 7티엠 파마 에이/에스
Publication of KR20070045153A publication Critical patent/KR20070045153A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
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    • C07D277/24—Radicals substituted by oxygen atoms
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    • C07D277/34—Oxygen atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
KR1020067027504A 2004-05-29 2005-05-30 의약용 씨알티에이치2 수용체 리간드 Ceased KR20070045153A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0412198.4 2004-05-29
GB0412198A GB0412198D0 (en) 2004-05-29 2004-05-29 Medicinal use of receptor ligands
GB0414196.6 2004-06-24
GB0414196A GB0414196D0 (en) 2004-06-24 2004-06-24 Medicinal use of receptor ligands
GB0424018A GB0424018D0 (en) 2004-10-29 2004-10-29 Medicinal use of receptor ligands
GB0424018.0 2004-10-29

Publications (1)

Publication Number Publication Date
KR20070045153A true KR20070045153A (ko) 2007-05-02

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ID=34993084

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Application Number Title Priority Date Filing Date
KR1020067027504A Ceased KR20070045153A (ko) 2004-05-29 2005-05-30 의약용 씨알티에이치2 수용체 리간드

Country Status (14)

Country Link
US (2) US8022063B2 (https=)
EP (2) EP1758579A1 (https=)
JP (1) JP2008500991A (https=)
KR (1) KR20070045153A (https=)
AU (1) AU2005247110B2 (https=)
BR (1) BRPI0511676A (https=)
CA (1) CA2568766A1 (https=)
CR (1) CR8838A (https=)
EA (1) EA014729B1 (https=)
IL (1) IL179694A (https=)
MX (1) MXPA06013912A (https=)
NO (1) NO20066048L (https=)
NZ (1) NZ551810A (https=)
WO (1) WO2005115382A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11957669B2 (en) 2017-08-11 2024-04-16 Amorepacific Corporation Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide
US12059412B2 (en) 2018-04-18 2024-08-13 Amorepacific Corporation Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethylpyridin-3-yl)-acrylamide and method for inhibiting crystal formation thereof

Families Citing this family (53)

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SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
GB0422057D0 (en) * 2004-10-05 2004-11-03 Astrazeneca Ab Novel compounds
JP5208510B2 (ja) 2004-11-23 2013-06-12 アストラゼネカ・アクチエボラーグ 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体
EA015358B1 (ru) * 2005-09-30 2011-06-30 Пульмаджен Терапьютикс (Эсме) Лимитед Хинолины и их терапевтическое применение
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
US8148572B2 (en) 2005-10-06 2012-04-03 Astrazeneca Ab Compounds
WO2007062678A1 (en) * 2005-11-29 2007-06-07 7Tm Pharma A/S Phenoxyacetic acid derivatives as crth2 receptor ligands
GB0524428D0 (en) * 2005-11-30 2006-01-11 7Tm Pharma As Medicinal use of receptor ligands
TWI392671B (zh) 2006-09-07 2013-04-11 Actelion Pharmaceuticals Ltd 吡啶-４-基衍生物
ES2400163T3 (es) 2006-09-08 2013-04-08 Actelion Pharmaceuticals Ltd. Derivados de piridil-3-ilo como agentes de inmunomodulación
MX2009002915A (es) 2006-09-21 2009-03-31 Actelion Pharmaceuticals Ltd Derivados de fenilo y su uso como inmunomoduladores.
EP2079734A1 (en) * 2006-10-25 2009-07-22 NeuroSearch A/S Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
ES2383239T3 (es) * 2006-12-14 2012-06-19 Astellas Pharma Inc. Compuestos de ácidos policíclicos útiles como antagonistas de CRTH2 y como agentes antialérgicos
PT2125797E (pt) 2007-03-16 2014-03-11 Actelion Pharmaceuticals Ltd Derivados aminopiridina como agonistas do receptor s1p1/edg1
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
US8598208B2 (en) 2007-08-17 2013-12-03 Actelion Pharmaceuticals Ltd. Pyridine derivatives as S1P1/EDG1 receptor modulators
ES2622423T3 (es) * 2007-10-04 2017-07-06 Merck Serono S.A. Derivados de oxadiazol
AU2008306886B2 (en) 2007-10-04 2014-01-16 Merck Serono S.A. Oxadiazole diaryl compounds
RU2010121969A (ru) 2007-11-01 2011-12-10 Актелион Фармасьютиклз Лтд (Ch) Новые производные пиримидина
PT2229358E (pt) 2007-12-14 2011-06-29 Pulmagen Therapeutics Asthma Ltd Indoles e sua utilização terapêutica
WO2009082398A1 (en) * 2007-12-21 2009-07-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
AU2009220893A1 (en) 2008-03-07 2009-09-11 Actelion Pharmaceuticals Ltd Novel aminomethyl benzene derivatives
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US8022063B2 (en) 2011-09-20
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