KR20070045153A - 의약용 씨알티에이치2 수용체 리간드 - Google Patents
의약용 씨알티에이치2 수용체 리간드 Download PDFInfo
- Publication number
- KR20070045153A KR20070045153A KR1020067027504A KR20067027504A KR20070045153A KR 20070045153 A KR20070045153 A KR 20070045153A KR 1020067027504 A KR1020067027504 A KR 1020067027504A KR 20067027504 A KR20067027504 A KR 20067027504A KR 20070045153 A KR20070045153 A KR 20070045153A
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- KR
- South Korea
- Prior art keywords
- bromo
- phenoxy
- carbonyl
- pyrazole
- acetic acid
- Prior art date
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- 0 C[n]1ncc(C(C2=C*(*)C=C*(*)C=C2OC(*)*)=O)c1 Chemical compound C[n]1ncc(C(C2=C*(*)C=C*(*)C=C2OC(*)*)=O)c1 0.000 description 13
- MSWCWDUVPOCYEV-UHFFFAOYSA-O Bc(cc1)cc(/C(/[OH2+])=N/C(C(C)(CC=C2)C=C2Cl)=N)c1OCC(O)=O Chemical compound Bc(cc1)cc(/C(/[OH2+])=N/C(C(C)(CC=C2)C=C2Cl)=N)c1OCC(O)=O MSWCWDUVPOCYEV-UHFFFAOYSA-O 0.000 description 1
- VBQFJRQIAWMAJY-UHFFFAOYSA-O Bc(cc1)cc(/C(/[OH2+])=N/C(c(cc2)ccc2OC)=N)c1OCC(O)=O Chemical compound Bc(cc1)cc(/C(/[OH2+])=N/C(c(cc2)ccc2OC)=N)c1OCC(O)=O VBQFJRQIAWMAJY-UHFFFAOYSA-O 0.000 description 1
- UDTMRWVMJVYDLZ-UHFFFAOYSA-N CC(C(CCC=C1)=C1O)=O Chemical compound CC(C(CCC=C1)=C1O)=O UDTMRWVMJVYDLZ-UHFFFAOYSA-N 0.000 description 1
- UXCCRERRAPFTAC-UHFFFAOYSA-O N=C(c(cc1)ccc1F)/N=C(/c(cc(cc1)Br)c1OCC(O)=O)\[OH2+] Chemical compound N=C(c(cc1)ccc1F)/N=C(/c(cc(cc1)Br)c1OCC(O)=O)\[OH2+] UXCCRERRAPFTAC-UHFFFAOYSA-O 0.000 description 1
- ZHLIHVKPXKOWLE-VONRICJUSA-N Nc1cc(Br)ccc1N/C=C(\C=N)/C(c(cc(cc1)[N+]([O-])=O)c1OCC(O)=O)=O Chemical compound Nc1cc(Br)ccc1N/C=C(\C=N)/C(c(cc(cc1)[N+]([O-])=O)c1OCC(O)=O)=O ZHLIHVKPXKOWLE-VONRICJUSA-N 0.000 description 1
- WHRYRALKFCAFQN-UHFFFAOYSA-N OC(COc(ccc(Br)c1)c1C(c1c[n](-c2ccccc2Oc2ccccc2)nc1)=O)=O Chemical compound OC(COc(ccc(Br)c1)c1C(c1c[n](-c2ccccc2Oc2ccccc2)nc1)=O)=O WHRYRALKFCAFQN-UHFFFAOYSA-N 0.000 description 1
- WPXLFNPBWUDPIQ-QYGRUQLRSA-O [NH2+]=C/C(/C(c(cc(cc1O)[U])c1OCC(O)=O)=O)=C\Nc1ccccc1 Chemical compound [NH2+]=C/C(/C(c(cc(cc1O)[U])c1OCC(O)=O)=O)=C\Nc1ccccc1 WPXLFNPBWUDPIQ-QYGRUQLRSA-O 0.000 description 1
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- C07D277/24—Radicals substituted by oxygen atoms
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- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0412198.4 | 2004-05-29 | ||
GB0412198A GB0412198D0 (en) | 2004-05-29 | 2004-05-29 | Medicinal use of receptor ligands |
GB0414196A GB0414196D0 (en) | 2004-06-24 | 2004-06-24 | Medicinal use of receptor ligands |
GB0414196.6 | 2004-06-24 | ||
GB0424018A GB0424018D0 (en) | 2004-10-29 | 2004-10-29 | Medicinal use of receptor ligands |
GB0424018.0 | 2004-10-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20070045153A true KR20070045153A (ko) | 2007-05-02 |
Family
ID=34993084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020067027504A KR20070045153A (ko) | 2004-05-29 | 2005-05-30 | 의약용 씨알티에이치2 수용체 리간드 |
Country Status (15)
Country | Link |
---|---|
US (2) | US8022063B2 (es) |
EP (2) | EP1758579A1 (es) |
JP (1) | JP2008500991A (es) |
KR (1) | KR20070045153A (es) |
AU (1) | AU2005247110B2 (es) |
BR (1) | BRPI0511676A (es) |
CA (1) | CA2568766A1 (es) |
CR (1) | CR8838A (es) |
EA (1) | EA014729B1 (es) |
HK (1) | HK1107763A1 (es) |
IL (1) | IL179694A (es) |
MX (1) | MXPA06013912A (es) |
NO (1) | NO20066048L (es) |
NZ (1) | NZ551810A (es) |
WO (1) | WO2005115382A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11957669B2 (en) | 2017-08-11 | 2024-04-16 | Amorepacific Corporation | Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
PT1817282E (pt) | 2004-11-23 | 2011-09-19 | Astrazeneca Ab | Derivados do ácido fenoxiacético úteis para tratar doenças respiratórias |
SI1928457T1 (sl) * | 2005-09-30 | 2013-06-28 | Pulmagen Therapeutics (Asthma) Limited | Kuinolilni in njihova terapevtska raba |
US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
GB0524428D0 (en) * | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
AU2007292993B2 (en) | 2006-09-07 | 2013-01-24 | Idorsia Pharmaceuticals Ltd | Pyridin-4-yl derivatives as immunomodulating agents |
AU2007292992B2 (en) | 2006-09-08 | 2013-01-10 | Actelion Pharmaceuticals Ltd | Pyridin-3-yl derivatives as immunomodulating agents |
AU2007298593A1 (en) | 2006-09-21 | 2008-03-27 | Actelion Pharmaceuticals Ltd | Phenyl derivatives and their use as immunomodulators |
JP2010507619A (ja) * | 2006-10-25 | 2010-03-11 | ノイロサーチ アクティーゼルスカブ | オキサジアゾール及びチアジアゾール化合物並びにニコチン性アセチルコリン受容体調節物質としてのその使用 |
EP2094662B1 (en) * | 2006-12-14 | 2012-04-11 | Astellas Pharma Inc. | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents |
MX2009009597A (es) | 2007-03-16 | 2009-09-16 | Actelion Pharmaceuticals Ltd | Derivados de amino-piridina como agonistas del receptor s1p1/edg1. |
UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
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-
2005
- 2005-05-30 AU AU2005247110A patent/AU2005247110B2/en not_active Ceased
- 2005-05-30 JP JP2007513846A patent/JP2008500991A/ja not_active Ceased
- 2005-05-30 CA CA002568766A patent/CA2568766A1/en not_active Abandoned
- 2005-05-30 KR KR1020067027504A patent/KR20070045153A/ko not_active Application Discontinuation
- 2005-05-30 NZ NZ551810A patent/NZ551810A/en unknown
- 2005-05-30 EA EA200602290A patent/EA014729B1/ru not_active IP Right Cessation
- 2005-05-30 MX MXPA06013912A patent/MXPA06013912A/es not_active Application Discontinuation
- 2005-05-30 WO PCT/EP2005/005884 patent/WO2005115382A1/en active Application Filing
- 2005-05-30 EP EP05770220A patent/EP1758579A1/en not_active Withdrawn
- 2005-05-30 EP EP10177122A patent/EP2336113A1/en not_active Withdrawn
- 2005-05-30 US US11/597,873 patent/US8022063B2/en not_active Expired - Fee Related
- 2005-05-30 BR BRPI0511676-7A patent/BRPI0511676A/pt not_active IP Right Cessation
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2006
- 2006-11-29 IL IL179694A patent/IL179694A/en not_active IP Right Cessation
- 2006-12-22 CR CR8838A patent/CR8838A/es not_active Application Discontinuation
- 2006-12-28 NO NO20066048A patent/NO20066048L/no not_active Application Discontinuation
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2007
- 2007-12-11 HK HK07113481.2A patent/HK1107763A1/xx not_active IP Right Cessation
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- 2011-06-02 US US13/151,317 patent/US20110269763A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11957669B2 (en) | 2017-08-11 | 2024-04-16 | Amorepacific Corporation | Pharmaceutical composition containing (R)-N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide |
Also Published As
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WO2005115382A1 (en) | 2005-12-08 |
AU2005247110B2 (en) | 2010-08-26 |
EA200602290A1 (ru) | 2007-06-29 |
MXPA06013912A (es) | 2007-07-18 |
US8022063B2 (en) | 2011-09-20 |
CR8838A (es) | 2009-01-12 |
IL179694A (en) | 2012-09-24 |
EA014729B1 (ru) | 2011-02-28 |
US20090099189A1 (en) | 2009-04-16 |
US20110269763A1 (en) | 2011-11-03 |
NO20066048L (no) | 2007-02-27 |
NZ551810A (en) | 2010-09-30 |
EP2336113A1 (en) | 2011-06-22 |
BRPI0511676A (pt) | 2008-01-08 |
HK1107763A1 (en) | 2008-04-18 |
IL179694A0 (en) | 2008-03-20 |
CA2568766A1 (en) | 2005-12-08 |
JP2008500991A (ja) | 2008-01-17 |
EP1758579A1 (en) | 2007-03-07 |
AU2005247110A1 (en) | 2005-12-08 |
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