KR20050109505A - 액정인 시아노피리돈 유도체 - Google Patents

액정인 시아노피리돈 유도체 Download PDF

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Publication number
KR20050109505A
KR20050109505A KR1020057015519A KR20057015519A KR20050109505A KR 20050109505 A KR20050109505 A KR 20050109505A KR 1020057015519 A KR1020057015519 A KR 1020057015519A KR 20057015519 A KR20057015519 A KR 20057015519A KR 20050109505 A KR20050109505 A KR 20050109505A
Authority
KR
South Korea
Prior art keywords
formula
cyanopyridone
group
carbon atoms
diyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020057015519A
Other languages
English (en)
Korean (ko)
Inventor
루이스 디안 파랜드
미카엘 헉크마이어
Original Assignee
메르크 파텐트 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메르크 파텐트 게엠베하 filed Critical 메르크 파텐트 게엠베하
Publication of KR20050109505A publication Critical patent/KR20050109505A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
    • C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
    • C09K19/3483—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a non-aromatic ring
    • G—PHYSICS
    • G02—OPTICS
    • G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/01—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour 
    • G02F1/13—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour  based on liquid crystals, e.g. single liquid crystal display cells
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2323/00—Functional layers of liquid crystal optical display excluding electroactive liquid crystal layer characterised by chemical composition
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2323/00—Functional layers of liquid crystal optical display excluding electroactive liquid crystal layer characterised by chemical composition
    • C09K2323/02—Alignment layer characterised by chemical composition

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nonlinear Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Pyridine Compounds (AREA)
  • Polarising Elements (AREA)
  • Cosmetics (AREA)
  • Electroluminescent Light Sources (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
KR1020057015519A 2003-02-22 2004-01-23 액정인 시아노피리돈 유도체 Ceased KR20050109505A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03003968 2003-02-22
EP03003968.9 2003-02-22

Publications (1)

Publication Number Publication Date
KR20050109505A true KR20050109505A (ko) 2005-11-21

Family

ID=32892857

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057015519A Ceased KR20050109505A (ko) 2003-02-22 2004-01-23 액정인 시아노피리돈 유도체

Country Status (7)

Country Link
US (1) US7442475B2 (https=)
EP (1) EP1594842A1 (https=)
JP (1) JP2006523184A (https=)
KR (1) KR20050109505A (https=)
CN (1) CN1753873A (https=)
TW (1) TW200504186A (https=)
WO (1) WO2004074253A1 (https=)

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EP1807085B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CA2580762A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
AU2005286648A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
EP2289510A1 (en) 2004-09-20 2011-03-02 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
CA2580857A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
US7829712B2 (en) 2004-09-20 2010-11-09 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
AR051091A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
LU91146B1 (en) 2005-03-10 2006-09-11 Ipalco Bv Device for suppying preconditioned air to an aircraft on the ground
AU2006343359A1 (en) 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
US8795630B2 (en) * 2008-08-29 2014-08-05 Treventis Corporation Butyrylcholinesterase ligands as diagnostic tools and treatment for diseases of the nervous system
US8257639B2 (en) * 2009-09-22 2012-09-04 Kent State University Method of making stimuli responsive liquid crystal-polymer composite fibers
US8168084B2 (en) 2009-12-18 2012-05-01 Vanderbilt University Polar nematic compounds
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
JP6223563B2 (ja) 2013-10-14 2017-11-01 エーザイ・アール・アンド・ディー・マネジメント株式会社 選択的に置換されたキノリン化合物
CN105636945B (zh) 2013-10-14 2017-11-17 卫材R&D管理有限公司 选择性取代的喹啉化合物
KR102392188B1 (ko) 2014-10-27 2022-04-28 삼성전자주식회사 편광 필름용 조성물, 편광 필름 및 표시 장치
US20170351130A1 (en) * 2014-12-19 2017-12-07 Merck Patent Gmbh Light modulation element
CN108341771B (zh) * 2017-01-21 2021-05-11 浙江九洲药业股份有限公司 一种3-氰基-2,6-二羟基吡啶钠水合物的制备方法
CN109705343B (zh) * 2018-12-12 2020-11-06 上海交通大学 薁基共价三嗪骨架及其应用
CN112980225A (zh) * 2021-02-25 2021-06-18 张家港莱拓新材料科技有限公司 一种新型可聚合介晶混合物涂料及其应用
CN113292576B (zh) * 2021-06-08 2023-05-30 山西大学 一类基于三苯胺的光热小分子及其制备方法和应用
KR20240035820A (ko) 2021-07-09 2024-03-18 플렉시움 인코포레이티드 Ikzf2를 조절하는 아릴 화합물 및 약학 조성물

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EP0180188B1 (en) * 1984-10-30 1992-04-15 Otsuka Pharmaceutical Co., Ltd. A composition for increasing the anti-cancer activity of an anti-cancer compound
US4864021A (en) 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
JPH0674248B2 (ja) * 1985-12-20 1994-09-21 チッソ株式会社 含窒素化合物
JPH0625119B2 (ja) * 1985-04-22 1994-04-06 チッソ株式会社 新規ピリジン誘導体
JPS6219568A (ja) * 1985-07-18 1987-01-28 Chisso Corp 新規ピリジン誘導体
JPS61204168A (ja) * 1985-03-06 1986-09-10 Chisso Corp ピリジン誘導体
JPS61233672A (ja) * 1985-04-08 1986-10-17 Chisso Corp 正の誘電異方性を示すピリジン誘導体
US4684477A (en) * 1985-03-06 1987-08-04 Chisso Corporation Pyridine derivatives and their use in liquid crystals
DE3786834T2 (de) * 1986-04-30 1994-03-03 Otsuka Pharma Co Ltd 5-Fluoro-Uracil-Derivate.
JPH0688996B2 (ja) * 1986-07-24 1994-11-09 大塚製薬株式会社 ５−フルオロウラシル誘導体
JPS63201127A (ja) * 1987-02-17 1988-08-19 Otsuka Pharmaceut Co Ltd ５−フルオロウラシル誘導体を含有する制癌剤
JPH0749422B2 (ja) * 1986-12-25 1995-05-31 大塚製薬株式会社 ５−フルオロ−５，６−ジヒドロウラシル誘導体
EP0310676A4 (de) 1987-04-07 1989-04-27 Pavljuchenko Assya I Flüssigkristallderivate von 2,5-disubstituierten pyridinen als komponenten von flüssigkristallmaterialien und flüssigkristallmaterial.
JPH02500274A (ja) * 1987-12-30 1990-02-01 パフルユチェンコ，アススヤ　イオシフォフナ 液晶材料の成分としての２，５‐二置換ピリジンの液晶誘導体および液晶材料
JP2700263B2 (ja) * 1988-12-16 1998-01-19 大塚製薬株式会社 ５―フルオロウラシル誘導体の製造法
JPH04288058A (ja) * 1990-07-11 1992-10-13 Fuji Photo Film Co Ltd フェニルピリジン化合物及びこれを含有する液晶組成物
JPH04217665A (ja) 1990-10-26 1992-08-07 Fuji Photo Film Co Ltd 分岐を有するフェニルピリジン化合物及びこれを含有する液晶組成物
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JPH0551536A (ja) * 1991-08-26 1993-03-02 Mitsubishi Kasei Corp パーフルオロアルキル基含有アゾ系色素
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JPH07207169A (ja) * 1994-01-12 1995-08-08 Mitsui Toatsu Chem Inc 偏光フィルム用アゾ系色素及びこれを用いた偏光フィルム
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US6664025B2 (en) * 2002-02-12 2003-12-16 Kodak Polychrome Graphics Llc Visible radiation sensitive composition

Also Published As

Publication number Publication date
US20060165916A1 (en) 2006-07-27
WO2004074253A1 (en) 2004-09-02
EP1594842A1 (en) 2005-11-16
TW200504186A (en) 2005-02-01
US7442475B2 (en) 2008-10-28
CN1753873A (zh) 2006-03-29
JP2006523184A (ja) 2006-10-12

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PA0105 International application

Patent event date: 20050822

Patent event code: PA01051R01D

Comment text: International Patent Application

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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20090123

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20101117

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20110221

Comment text: Decision to Refuse Application

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Patent event date: 20101117

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I