KR102866583B1 - 항-met 항체, met에 결합하는 이중특이적 항원 결합 분자, 및 그 사용 방법 - Google Patents

항-met 항체, met에 결합하는 이중특이적 항원 결합 분자, 및 그 사용 방법

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KR102866583B1
KR102866583B1 KR1020237023645A KR20237023645A KR102866583B1 KR 102866583 B1 KR102866583 B1 KR 102866583B1 KR 1020237023645 A KR1020237023645 A KR 1020237023645A KR 20237023645 A KR20237023645 A KR 20237023645A KR 102866583 B1 KR102866583 B1 KR 102866583B1
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met
antibody
binding
antibodies
antigen
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KR1020237023645A
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Korean (ko)
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KR20230110825A (ko
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로버트 밥
강 첸
크리스토퍼 달리
존 다실바
더글라스 맥도날드
토마스 니톨리
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리제너론 파마슈티칼스 인코포레이티드
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Priority to KR1020257032243A priority Critical patent/KR20250150663A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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