KR102787394B1 - MAdCAM에 대한 항체 - Google Patents

MAdCAM에 대한 항체 Download PDF

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Publication number
KR102787394B1
KR102787394B1 KR1020207004168A KR20207004168A KR102787394B1 KR 102787394 B1 KR102787394 B1 KR 102787394B1 KR 1020207004168 A KR1020207004168 A KR 1020207004168A KR 20207004168 A KR20207004168 A KR 20207004168A KR 102787394 B1 KR102787394 B1 KR 102787394B1
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South Korea
Prior art keywords
antibody
madcam
antibodies
delete delete
seq
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English (en)
Korean (ko)
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KR20200028006A (ko
Inventor
카린 앤더슨
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화이자 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020207004168A 2017-07-14 2018-07-13 MAdCAM에 대한 항체 Active KR102787394B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762532809P 2017-07-14 2017-07-14
US62/532,809 2017-07-14
PCT/US2018/042052 WO2019014572A1 (en) 2017-07-14 2018-07-13 ANTIBODIES DIRECTED AGAINST MADCAM

Publications (2)

Publication Number Publication Date
KR20200028006A KR20200028006A (ko) 2020-03-13
KR102787394B1 true KR102787394B1 (ko) 2025-03-26

Family

ID=63209653

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207004168A Active KR102787394B1 (ko) 2017-07-14 2018-07-13 MAdCAM에 대한 항체

Country Status (25)

Country Link
US (2) US20190169291A1 (https=)
EP (1) EP3652211A1 (https=)
JP (1) JP7160491B2 (https=)
KR (1) KR102787394B1 (https=)
CN (2) CN111032694B (https=)
AR (1) AR112336A1 (https=)
AU (1) AU2018300189B2 (https=)
BR (1) BR112020000698A2 (https=)
CA (1) CA3069914A1 (https=)
CL (1) CL2020000102A1 (https=)
CO (1) CO2020000352A2 (https=)
CR (1) CR20200076A (https=)
CU (1) CU20200002A7 (https=)
DO (1) DOP2020000005A (https=)
EA (1) EA202090286A1 (https=)
EC (1) ECSP20011317A (https=)
IL (1) IL272015A (https=)
MA (1) MA48241A1 (https=)
MX (1) MX2023014363A (https=)
NI (1) NI202000004A (https=)
PE (1) PE20200616A1 (https=)
PH (1) PH12020500100A1 (https=)
SG (1) SG11202000298VA (https=)
TW (1) TW201920266A (https=)
WO (1) WO2019014572A1 (https=)

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Also Published As

Publication number Publication date
EP3652211A1 (en) 2020-05-20
EA202090286A1 (ru) 2020-05-12
AU2018300189A1 (en) 2020-01-30
AU2018300189B2 (en) 2025-05-15
MX2023014363A (es) 2023-12-15
AR112336A1 (es) 2019-10-16
DOP2020000005A (es) 2021-02-15
PH12020500100A1 (en) 2020-09-14
US20190169291A1 (en) 2019-06-06
WO2019014572A1 (en) 2019-01-17
CA3069914A1 (en) 2019-01-17
PE20200616A1 (es) 2020-03-11
CR20200076A (es) 2020-06-10
KR20200028006A (ko) 2020-03-13
NI202000004A (es) 2020-03-30
US11802156B2 (en) 2023-10-31
IL272015A (en) 2020-02-27
CL2020000102A1 (es) 2020-10-09
CO2020000352A2 (es) 2020-04-13
ECSP20011317A (es) 2020-12-31
TW201920266A (zh) 2019-06-01
CN111032694B (zh) 2024-03-08
CN118406148A (zh) 2024-07-30
MA48241A1 (fr) 2021-03-31
SG11202000298VA (en) 2020-02-27
JP7160491B2 (ja) 2022-10-25
CU20200002A7 (es) 2020-11-30
CN111032694A (zh) 2020-04-17
US20220119521A1 (en) 2022-04-21
JP2020533953A (ja) 2020-11-26
BR112020000698A2 (pt) 2020-07-14

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