KR102787394B1 - MAdCAM에 대한 항체 - Google Patents

MAdCAM에 대한 항체 Download PDF

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Publication number
KR102787394B1
KR102787394B1 KR1020207004168A KR20207004168A KR102787394B1 KR 102787394 B1 KR102787394 B1 KR 102787394B1 KR 1020207004168 A KR1020207004168 A KR 1020207004168A KR 20207004168 A KR20207004168 A KR 20207004168A KR 102787394 B1 KR102787394 B1 KR 102787394B1
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South Korea
Prior art keywords
antibody
madcam
antibodies
delete delete
seq
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English (en)
Korean (ko)
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KR20200028006A (ko
Inventor
카린 앤더슨
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화이자 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020207004168A 2017-07-14 2018-07-13 MAdCAM에 대한 항체 Active KR102787394B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762532809P 2017-07-14 2017-07-14
US62/532,809 2017-07-14
PCT/US2018/042052 WO2019014572A1 (en) 2017-07-14 2018-07-13 ANTIBODIES DIRECTED AGAINST MADCAM

Publications (2)

Publication Number Publication Date
KR20200028006A KR20200028006A (ko) 2020-03-13
KR102787394B1 true KR102787394B1 (ko) 2025-03-26

Family

ID=63209653

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207004168A Active KR102787394B1 (ko) 2017-07-14 2018-07-13 MAdCAM에 대한 항체

Country Status (25)

Country Link
US (2) US20190169291A1 (enExample)
EP (1) EP3652211A1 (enExample)
JP (1) JP7160491B2 (enExample)
KR (1) KR102787394B1 (enExample)
CN (2) CN111032694B (enExample)
AR (1) AR112336A1 (enExample)
AU (1) AU2018300189B2 (enExample)
BR (1) BR112020000698A2 (enExample)
CA (1) CA3069914A1 (enExample)
CL (1) CL2020000102A1 (enExample)
CO (1) CO2020000352A2 (enExample)
CR (1) CR20200076A (enExample)
CU (1) CU20200002A7 (enExample)
DO (1) DOP2020000005A (enExample)
EA (1) EA202090286A1 (enExample)
EC (1) ECSP20011317A (enExample)
IL (1) IL272015A (enExample)
MA (1) MA48241A1 (enExample)
MX (1) MX2023014363A (enExample)
NI (1) NI202000004A (enExample)
PE (1) PE20200616A1 (enExample)
PH (1) PH12020500100A1 (enExample)
SG (1) SG11202000298VA (enExample)
TW (1) TW201920266A (enExample)
WO (1) WO2019014572A1 (enExample)

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* Cited by examiner, † Cited by third party
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EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
WO2024110868A1 (en) 2022-11-22 2024-05-30 Takeda Pharmaceutical Company Limited DOSAGE REGIMEN OF MAdCAM-1 ANTIBODY FOR TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS

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NI202000004A (es) 2020-03-30
CO2020000352A2 (es) 2020-04-13
EP3652211A1 (en) 2020-05-20
CA3069914A1 (en) 2019-01-17
TW201920266A (zh) 2019-06-01
WO2019014572A1 (en) 2019-01-17
AU2018300189A1 (en) 2020-01-30
IL272015A (en) 2020-02-27
US20190169291A1 (en) 2019-06-06
AR112336A1 (es) 2019-10-16
CN111032694A (zh) 2020-04-17
KR20200028006A (ko) 2020-03-13
CL2020000102A1 (es) 2020-10-09
CR20200076A (es) 2020-06-10
JP7160491B2 (ja) 2022-10-25
PH12020500100A1 (en) 2020-09-14
EA202090286A1 (ru) 2020-05-12
US20220119521A1 (en) 2022-04-21
SG11202000298VA (en) 2020-02-27
CN118406148A (zh) 2024-07-30
CN111032694B (zh) 2024-03-08
AU2018300189B2 (en) 2025-05-15
CU20200002A7 (es) 2020-11-30
PE20200616A1 (es) 2020-03-11
MX2023014363A (es) 2023-12-15
US11802156B2 (en) 2023-10-31
ECSP20011317A (es) 2020-12-31
MA48241A1 (fr) 2021-03-31
BR112020000698A2 (pt) 2020-07-14
DOP2020000005A (es) 2021-02-15
JP2020533953A (ja) 2020-11-26

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