KR101805754B1 - 단백질 수용체 티로신 키나아제 억제제의 조성물 - Google Patents
단백질 수용체 티로신 키나아제 억제제의 조성물 Download PDFInfo
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- KR101805754B1 KR101805754B1 KR1020117015933A KR20117015933A KR101805754B1 KR 101805754 B1 KR101805754 B1 KR 101805754B1 KR 1020117015933 A KR1020117015933 A KR 1020117015933A KR 20117015933 A KR20117015933 A KR 20117015933A KR 101805754 B1 KR101805754 B1 KR 101805754B1
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- 0 *C1C2=NI=*I=C2*1* Chemical compound *C1C2=NI=*I=C2*1* 0.000 description 3
- HQGWDZBNXDMVSA-PCLIKHOPSA-N CCC(c1c(/C=C(\c(ncnc2)c2N2Cc(cccc3)c3F)/C2=O)ccc(C(NCCCN2CCCC2)=O)c1)I Chemical compound CCC(c1c(/C=C(\c(ncnc2)c2N2Cc(cccc3)c3F)/C2=O)ccc(C(NCCCN2CCCC2)=O)c1)I HQGWDZBNXDMVSA-PCLIKHOPSA-N 0.000 description 1
- ULTRTHDAMISTHF-UHFFFAOYSA-N Cc(ccc(Cl)c1)c1N1CCN(CCCNC(c2ccc(C3=NC=CC3C(N3Cc4ccccc4)=O)c3c2)=O)CC1 Chemical compound Cc(ccc(Cl)c1)c1N1CCN(CCCNC(c2ccc(C3=NC=CC3C(N3Cc4ccccc4)=O)c3c2)=O)CC1 ULTRTHDAMISTHF-UHFFFAOYSA-N 0.000 description 1
- PHVKNKATKXLRSG-MXNGAVTRSA-N O=C(c(cc1)ccc1/N=C(/c1ccccc1N1Cc(cccc2)c2F)\C1=O)NCCCN1CCCC1 Chemical compound O=C(c(cc1)ccc1/N=C(/c1ccccc1N1Cc(cccc2)c2F)\C1=O)NCCCN1CCCC1 PHVKNKATKXLRSG-MXNGAVTRSA-N 0.000 description 1
- GQFOQEMWQTXJKU-QOMWVZHYSA-N O=C(c1ccc(/C=C(/c(cccc2)c2N2Cc(cccc3)c3F)\C2=O)cc1)NCCCN1CCCC1 Chemical compound O=C(c1ccc(/C=C(/c(cccc2)c2N2Cc(cccc3)c3F)\C2=O)cc1)NCCCN1CCCC1 GQFOQEMWQTXJKU-QOMWVZHYSA-N 0.000 description 1
- SISACRKVAFUAPR-UHFFFAOYSA-N O=C(c1ccc(CC(c(cccc2)c2N2Cc3ccccc3F)C2=O)cc1)NCCCN1CCCC1 Chemical compound O=C(c1ccc(CC(c(cccc2)c2N2Cc3ccccc3F)C2=O)cc1)NCCCN1CCCC1 SISACRKVAFUAPR-UHFFFAOYSA-N 0.000 description 1
- MMUWXZUTOXDAGI-UHFFFAOYSA-N OC(c(cc1)ccc1Nc(cc(c1n[o]c(-c2ccccc22)c11)N(CC3)CCN3C3CCCCC3)c1C2=O)=O Chemical compound OC(c(cc1)ccc1Nc(cc(c1n[o]c(-c2ccccc22)c11)N(CC3)CCN3C3CCCCC3)c1C2=O)=O MMUWXZUTOXDAGI-UHFFFAOYSA-N 0.000 description 1
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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