KR101762966B1 - 항체 제제 - Google Patents

항체 제제 Download PDF

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Publication number
KR101762966B1
KR101762966B1 KR1020117015821A KR20117015821A KR101762966B1 KR 101762966 B1 KR101762966 B1 KR 101762966B1 KR 1020117015821 A KR1020117015821 A KR 1020117015821A KR 20117015821 A KR20117015821 A KR 20117015821A KR 101762966 B1 KR101762966 B1 KR 101762966B1
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KR
South Korea
Prior art keywords
formulation
antibody
acz885
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020117015821A
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English (en)
Korean (ko)
Other versions
KR20120009421A (ko
Inventor
요아힘 몸
한스-요아힘 발니
Original Assignee
노파르티스 아게
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40637230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101762966(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20120009421A publication Critical patent/KR20120009421A/ko
Application granted granted Critical
Publication of KR101762966B1 publication Critical patent/KR101762966B1/ko
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020117015821A 2008-12-10 2009-12-09 항체 제제 Active KR101762966B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08170884A EP2196476A1 (en) 2008-12-10 2008-12-10 Antibody formulation
EP08170884.4 2008-12-10
PCT/EP2009/066675 WO2010066762A1 (en) 2008-12-10 2009-12-09 Antibody formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020177009939A Division KR20170044211A (ko) 2008-12-10 2009-12-09 항체 제제

Publications (2)

Publication Number Publication Date
KR20120009421A KR20120009421A (ko) 2012-01-31
KR101762966B1 true KR101762966B1 (ko) 2017-07-31

Family

ID=40637230

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020117015821A Active KR101762966B1 (ko) 2008-12-10 2009-12-09 항체 제제
KR1020177009939A Ceased KR20170044211A (ko) 2008-12-10 2009-12-09 항체 제제

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020177009939A Ceased KR20170044211A (ko) 2008-12-10 2009-12-09 항체 제제

Country Status (31)

Country Link
US (3) US20110236398A1 (enExample)
EP (4) EP2196476A1 (enExample)
JP (5) JP6143416B2 (enExample)
KR (2) KR101762966B1 (enExample)
CN (3) CN102245639B (enExample)
AU (1) AU2009324371B2 (enExample)
BR (1) BRPI0922730A2 (enExample)
CA (1) CA2745938C (enExample)
CL (1) CL2011001406A1 (enExample)
CO (1) CO6361952A2 (enExample)
CY (2) CY1117735T1 (enExample)
DK (2) DK3072906T3 (enExample)
EC (1) ECSP11011192A (enExample)
ES (2) ES2900624T3 (enExample)
HR (2) HRP20211899T1 (enExample)
HU (2) HUE028408T2 (enExample)
IL (3) IL264316B2 (enExample)
LT (1) LT3072906T (enExample)
MA (1) MA33023B1 (enExample)
MX (1) MX2011006242A (enExample)
MY (2) MY166050A (enExample)
NZ (1) NZ592918A (enExample)
PE (1) PE20120342A1 (enExample)
PL (2) PL3072906T3 (enExample)
PT (2) PT3072906T (enExample)
RU (2) RU2745601C2 (enExample)
SI (2) SI2376533T1 (enExample)
SM (1) SMT201600222B (enExample)
TN (1) TN2011000229A1 (enExample)
WO (1) WO2010066762A1 (enExample)
ZA (1) ZA201103362B (enExample)

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Also Published As

Publication number Publication date
AU2009324371B2 (en) 2013-10-10
MY166050A (en) 2018-05-22
RU2745601C2 (ru) 2021-03-29
CY1117735T1 (el) 2017-05-17
EP3072906B1 (en) 2021-09-08
CA2745938A1 (en) 2010-06-17
IL264316B2 (en) 2024-01-01
CO6361952A2 (es) 2012-01-20
PE20120342A1 (es) 2012-04-24
HRP20211899T1 (hr) 2022-03-04
JP2012511540A (ja) 2012-05-24
BRPI0922730A2 (pt) 2018-11-06
KR20120009421A (ko) 2012-01-31
PL2376533T3 (pl) 2016-09-30
PT2376533T (pt) 2016-07-13
US20120315285A1 (en) 2012-12-13
EP2376533A1 (en) 2011-10-19
EP3072906A1 (en) 2016-09-28
DK3072906T3 (da) 2021-12-13
LT3072906T (lt) 2021-12-27
JP2015231997A (ja) 2015-12-24
RU2015132431A3 (enExample) 2018-12-24
DK2376533T3 (en) 2016-06-27
MY157772A (en) 2016-07-29
NZ592918A (en) 2012-12-21
RU2015132431A (ru) 2018-12-24
ES2579835T3 (es) 2016-08-17
MX2011006242A (es) 2011-06-24
TN2011000229A1 (en) 2012-12-17
HRP20160754T1 (hr) 2016-08-12
IL276622A (en) 2020-09-30
AU2009324371A1 (en) 2011-06-23
CY1124844T1 (el) 2022-11-25
MA33023B1 (fr) 2012-02-01
SMT201600222B (it) 2016-08-31
EP2376533B1 (en) 2016-03-30
SI2376533T1 (sl) 2016-07-29
US20110236398A1 (en) 2011-09-29
JP2020203889A (ja) 2020-12-24
HUE056626T2 (hu) 2022-02-28
JP2023109938A (ja) 2023-08-08
JP2018168158A (ja) 2018-11-01
US8623367B2 (en) 2014-01-07
RU2563179C2 (ru) 2015-09-20
PL3072906T3 (pl) 2022-01-24
CL2011001406A1 (es) 2012-03-30
JP7286595B2 (ja) 2023-06-05
SI3072906T1 (sl) 2022-01-31
ECSP11011192A (es) 2011-08-31
RU2011127913A (ru) 2013-01-20
CA2745938C (en) 2018-04-24
CN104399076B (zh) 2021-09-14
CN102245639A (zh) 2011-11-16
WO2010066762A1 (en) 2010-06-17
CN102245639B (zh) 2014-12-24
EP3792282A1 (en) 2021-03-17
IL212922B (en) 2019-02-28
IL264316B1 (en) 2023-09-01
IL264316A (en) 2019-02-28
ES2900624T3 (es) 2022-03-17
IL212922A0 (en) 2011-07-31
HUE028408T2 (en) 2016-12-28
EP2196476A1 (en) 2010-06-16
CN104399076A (zh) 2015-03-11
US20200384108A1 (en) 2020-12-10
KR20170044211A (ko) 2017-04-24
HK1159130A1 (zh) 2012-07-27
ZA201103362B (en) 2012-01-25
CN114225022A (zh) 2022-03-25
PT3072906T (pt) 2021-12-14
JP6143416B2 (ja) 2017-06-07

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