ES2900624T3 - Formulación de anticuerpos - Google Patents

Formulación de anticuerpos Download PDF

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Publication number
ES2900624T3
ES2900624T3 ES16162699T ES16162699T ES2900624T3 ES 2900624 T3 ES2900624 T3 ES 2900624T3 ES 16162699 T ES16162699 T ES 16162699T ES 16162699 T ES16162699 T ES 16162699T ES 2900624 T3 ES2900624 T3 ES 2900624T3
Authority
ES
Spain
Prior art keywords
formulation
antibody
formulations
acz885
months
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16162699T
Other languages
English (en)
Spanish (es)
Inventor
Joachim Momm
Hans-Joachim Wallny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40637230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2900624(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2900624T3 publication Critical patent/ES2900624T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
ES16162699T 2008-12-10 2009-12-09 Formulación de anticuerpos Active ES2900624T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08170884A EP2196476A1 (en) 2008-12-10 2008-12-10 Antibody formulation

Publications (1)

Publication Number Publication Date
ES2900624T3 true ES2900624T3 (es) 2022-03-17

Family

ID=40637230

Family Applications (2)

Application Number Title Priority Date Filing Date
ES16162699T Active ES2900624T3 (es) 2008-12-10 2009-12-09 Formulación de anticuerpos
ES09764858.8T Active ES2579835T3 (es) 2008-12-10 2009-12-09 Formulación de anticuerpo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES09764858.8T Active ES2579835T3 (es) 2008-12-10 2009-12-09 Formulación de anticuerpo

Country Status (31)

Country Link
US (3) US20110236398A1 (enExample)
EP (4) EP2196476A1 (enExample)
JP (5) JP6143416B2 (enExample)
KR (2) KR101762966B1 (enExample)
CN (3) CN104399076B (enExample)
AU (1) AU2009324371B2 (enExample)
BR (1) BRPI0922730A2 (enExample)
CA (1) CA2745938C (enExample)
CL (1) CL2011001406A1 (enExample)
CO (1) CO6361952A2 (enExample)
CY (2) CY1117735T1 (enExample)
DK (2) DK2376533T3 (enExample)
EC (1) ECSP11011192A (enExample)
ES (2) ES2900624T3 (enExample)
HR (2) HRP20211899T1 (enExample)
HU (2) HUE028408T2 (enExample)
IL (3) IL264316B2 (enExample)
LT (1) LT3072906T (enExample)
MA (1) MA33023B1 (enExample)
MX (1) MX2011006242A (enExample)
MY (2) MY166050A (enExample)
NZ (1) NZ592918A (enExample)
PE (1) PE20120342A1 (enExample)
PL (2) PL2376533T3 (enExample)
PT (2) PT2376533T (enExample)
RU (2) RU2745601C2 (enExample)
SI (2) SI2376533T1 (enExample)
SM (1) SMT201600222B (enExample)
TN (1) TN2011000229A1 (enExample)
WO (1) WO2010066762A1 (enExample)
ZA (1) ZA201103362B (enExample)

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US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
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RU2649364C2 (ru) 2011-12-16 2018-04-02 Модерна Терапьютикс, Инк. Составы на основе модифицированного нуклеозида, нуклеотида и нуклеиновой кислоты
WO2013123114A2 (en) * 2012-02-16 2013-08-22 Santarus, Inc. Antibody formulations
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US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
EP3520821A1 (en) 2012-04-02 2019-08-07 Moderna Therapeutics, Inc. Modified polynucleotides for the production of biologics and proteins associated with human disease
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US8883979B2 (en) * 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
US8613919B1 (en) 2012-08-31 2013-12-24 Bayer Healthcare, Llc High concentration antibody and protein formulations
US9592297B2 (en) 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
UA115789C2 (uk) 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Композиція антитіла до cd105 та її застосування
HK1208231A1 (en) * 2012-09-20 2016-02-26 Morphosys Ag Treatment for rheumatoid arthritis
WO2014078502A1 (en) * 2012-11-16 2014-05-22 Novartis Ag Use of il-1 beta binding antibodies for treating peripheral arterial disease
SI2922554T1 (sl) 2012-11-26 2022-06-30 Modernatx, Inc. Terminalno modificirana RNA
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CA2906101A1 (en) * 2013-03-15 2014-09-18 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
TWI679019B (zh) 2013-04-29 2019-12-11 法商賽諾菲公司 抗il-4/抗il-13之雙特異性抗體調配物
NL1040254C2 (en) * 2013-05-17 2014-11-24 Ablynx Nv Stable formulations of immunoglobulin single variable domains and uses thereof.
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
JP6707469B2 (ja) * 2014-05-28 2020-06-10 ノノ インコーポレイテッド アセチル化スカベンジャーを含むTat−NR2B9cの凍結乾燥製剤
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Also Published As

Publication number Publication date
KR20170044211A (ko) 2017-04-24
ZA201103362B (en) 2012-01-25
ES2579835T3 (es) 2016-08-17
EP2376533A1 (en) 2011-10-19
ECSP11011192A (es) 2011-08-31
CL2011001406A1 (es) 2012-03-30
MY157772A (en) 2016-07-29
NZ592918A (en) 2012-12-21
RU2745601C2 (ru) 2021-03-29
SI2376533T1 (sl) 2016-07-29
CN102245639A (zh) 2011-11-16
PE20120342A1 (es) 2012-04-24
MA33023B1 (fr) 2012-02-01
SI3072906T1 (sl) 2022-01-31
EP2376533B1 (en) 2016-03-30
RU2015132431A3 (enExample) 2018-12-24
CA2745938A1 (en) 2010-06-17
JP2023109938A (ja) 2023-08-08
TN2011000229A1 (en) 2012-12-17
CN102245639B (zh) 2014-12-24
PL2376533T3 (pl) 2016-09-30
AU2009324371A1 (en) 2011-06-23
US20110236398A1 (en) 2011-09-29
PT3072906T (pt) 2021-12-14
AU2009324371B2 (en) 2013-10-10
DK3072906T3 (da) 2021-12-13
JP7286595B2 (ja) 2023-06-05
EP3072906A1 (en) 2016-09-28
IL276622A (en) 2020-09-30
US20200384108A1 (en) 2020-12-10
WO2010066762A1 (en) 2010-06-17
IL212922A0 (en) 2011-07-31
RU2563179C2 (ru) 2015-09-20
CY1117735T1 (el) 2017-05-17
EP3072906B1 (en) 2021-09-08
PL3072906T3 (pl) 2022-01-24
LT3072906T (lt) 2021-12-27
HRP20211899T1 (hr) 2022-03-04
KR101762966B1 (ko) 2017-07-31
CN114225022A (zh) 2022-03-25
HUE028408T2 (en) 2016-12-28
JP2015231997A (ja) 2015-12-24
DK2376533T3 (en) 2016-06-27
HRP20160754T1 (hr) 2016-08-12
MX2011006242A (es) 2011-06-24
RU2011127913A (ru) 2013-01-20
IL264316A (en) 2019-02-28
BRPI0922730A2 (pt) 2018-11-06
MY166050A (en) 2018-05-22
EP2196476A1 (en) 2010-06-16
RU2015132431A (ru) 2018-12-24
EP3792282A1 (en) 2021-03-17
JP6143416B2 (ja) 2017-06-07
SMT201600222B (it) 2016-08-31
JP2020203889A (ja) 2020-12-24
IL212922B (en) 2019-02-28
IL264316B1 (en) 2023-09-01
CN104399076B (zh) 2021-09-14
JP2012511540A (ja) 2012-05-24
PT2376533T (pt) 2016-07-13
CA2745938C (en) 2018-04-24
US8623367B2 (en) 2014-01-07
KR20120009421A (ko) 2012-01-31
CY1124844T1 (el) 2022-11-25
HUE056626T2 (hu) 2022-02-28
US20120315285A1 (en) 2012-12-13
JP2018168158A (ja) 2018-11-01
IL264316B2 (en) 2024-01-01
CN104399076A (zh) 2015-03-11
CO6361952A2 (es) 2012-01-20
HK1159130A1 (zh) 2012-07-27

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