DK2376533T3 - antibody Formulation - Google Patents

antibody Formulation Download PDF

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Publication number
DK2376533T3
DK2376533T3 DK09764858.8T DK09764858T DK2376533T3 DK 2376533 T3 DK2376533 T3 DK 2376533T3 DK 09764858 T DK09764858 T DK 09764858T DK 2376533 T3 DK2376533 T3 DK 2376533T3
Authority
DK
Denmark
Prior art keywords
formulation
formulations
antibody
acz885
formulation according
Prior art date
Application number
DK09764858.8T
Other languages
Danish (da)
English (en)
Inventor
Joachim Momm
Hans-Joachim Wallny
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40637230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2376533(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK2376533T3 publication Critical patent/DK2376533T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK09764858.8T 2008-12-10 2009-12-09 antibody Formulation DK2376533T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08170884A EP2196476A1 (en) 2008-12-10 2008-12-10 Antibody formulation
PCT/EP2009/066675 WO2010066762A1 (en) 2008-12-10 2009-12-09 Antibody formulation

Publications (1)

Publication Number Publication Date
DK2376533T3 true DK2376533T3 (en) 2016-06-27

Family

ID=40637230

Family Applications (2)

Application Number Title Priority Date Filing Date
DK09764858.8T DK2376533T3 (en) 2008-12-10 2009-12-09 antibody Formulation
DK16162699.9T DK3072906T3 (da) 2008-12-10 2009-12-09 Antistofformulering

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK16162699.9T DK3072906T3 (da) 2008-12-10 2009-12-09 Antistofformulering

Country Status (31)

Country Link
US (3) US20110236398A1 (enExample)
EP (4) EP2196476A1 (enExample)
JP (5) JP6143416B2 (enExample)
KR (2) KR101762966B1 (enExample)
CN (3) CN104399076B (enExample)
AU (1) AU2009324371B2 (enExample)
BR (1) BRPI0922730A2 (enExample)
CA (1) CA2745938C (enExample)
CL (1) CL2011001406A1 (enExample)
CO (1) CO6361952A2 (enExample)
CY (2) CY1117735T1 (enExample)
DK (2) DK2376533T3 (enExample)
EC (1) ECSP11011192A (enExample)
ES (2) ES2900624T3 (enExample)
HR (2) HRP20211899T1 (enExample)
HU (2) HUE028408T2 (enExample)
IL (3) IL264316B2 (enExample)
LT (1) LT3072906T (enExample)
MA (1) MA33023B1 (enExample)
MX (1) MX2011006242A (enExample)
MY (2) MY166050A (enExample)
NZ (1) NZ592918A (enExample)
PE (1) PE20120342A1 (enExample)
PL (2) PL2376533T3 (enExample)
PT (2) PT2376533T (enExample)
RU (2) RU2745601C2 (enExample)
SI (2) SI2376533T1 (enExample)
SM (1) SMT201600222B (enExample)
TN (1) TN2011000229A1 (enExample)
WO (1) WO2010066762A1 (enExample)
ZA (1) ZA201103362B (enExample)

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US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
CA2906101A1 (en) * 2013-03-15 2014-09-18 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
TWI679019B (zh) 2013-04-29 2019-12-11 法商賽諾菲公司 抗il-4/抗il-13之雙特異性抗體調配物
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Also Published As

Publication number Publication date
KR20170044211A (ko) 2017-04-24
ZA201103362B (en) 2012-01-25
ES2579835T3 (es) 2016-08-17
EP2376533A1 (en) 2011-10-19
ECSP11011192A (es) 2011-08-31
CL2011001406A1 (es) 2012-03-30
MY157772A (en) 2016-07-29
NZ592918A (en) 2012-12-21
RU2745601C2 (ru) 2021-03-29
SI2376533T1 (sl) 2016-07-29
CN102245639A (zh) 2011-11-16
PE20120342A1 (es) 2012-04-24
MA33023B1 (fr) 2012-02-01
SI3072906T1 (sl) 2022-01-31
EP2376533B1 (en) 2016-03-30
RU2015132431A3 (enExample) 2018-12-24
CA2745938A1 (en) 2010-06-17
JP2023109938A (ja) 2023-08-08
TN2011000229A1 (en) 2012-12-17
CN102245639B (zh) 2014-12-24
PL2376533T3 (pl) 2016-09-30
AU2009324371A1 (en) 2011-06-23
US20110236398A1 (en) 2011-09-29
PT3072906T (pt) 2021-12-14
AU2009324371B2 (en) 2013-10-10
DK3072906T3 (da) 2021-12-13
JP7286595B2 (ja) 2023-06-05
EP3072906A1 (en) 2016-09-28
IL276622A (en) 2020-09-30
US20200384108A1 (en) 2020-12-10
WO2010066762A1 (en) 2010-06-17
IL212922A0 (en) 2011-07-31
RU2563179C2 (ru) 2015-09-20
CY1117735T1 (el) 2017-05-17
EP3072906B1 (en) 2021-09-08
PL3072906T3 (pl) 2022-01-24
LT3072906T (lt) 2021-12-27
HRP20211899T1 (hr) 2022-03-04
KR101762966B1 (ko) 2017-07-31
CN114225022A (zh) 2022-03-25
HUE028408T2 (en) 2016-12-28
JP2015231997A (ja) 2015-12-24
HRP20160754T1 (hr) 2016-08-12
MX2011006242A (es) 2011-06-24
RU2011127913A (ru) 2013-01-20
IL264316A (en) 2019-02-28
ES2900624T3 (es) 2022-03-17
BRPI0922730A2 (pt) 2018-11-06
MY166050A (en) 2018-05-22
EP2196476A1 (en) 2010-06-16
RU2015132431A (ru) 2018-12-24
EP3792282A1 (en) 2021-03-17
JP6143416B2 (ja) 2017-06-07
SMT201600222B (it) 2016-08-31
JP2020203889A (ja) 2020-12-24
IL212922B (en) 2019-02-28
IL264316B1 (en) 2023-09-01
CN104399076B (zh) 2021-09-14
JP2012511540A (ja) 2012-05-24
PT2376533T (pt) 2016-07-13
CA2745938C (en) 2018-04-24
US8623367B2 (en) 2014-01-07
KR20120009421A (ko) 2012-01-31
CY1124844T1 (el) 2022-11-25
HUE056626T2 (hu) 2022-02-28
US20120315285A1 (en) 2012-12-13
JP2018168158A (ja) 2018-11-01
IL264316B2 (en) 2024-01-01
CN104399076A (zh) 2015-03-11
CO6361952A2 (es) 2012-01-20
HK1159130A1 (zh) 2012-07-27

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