KR101627901B1 - 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진 - Google Patents

인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진 Download PDF

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KR101627901B1
KR101627901B1 KR1020137029366A KR20137029366A KR101627901B1 KR 101627901 B1 KR101627901 B1 KR 101627901B1 KR 1020137029366 A KR1020137029366 A KR 1020137029366A KR 20137029366 A KR20137029366 A KR 20137029366A KR 101627901 B1 KR101627901 B1 KR 101627901B1
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compound
piperazine
mixture
phenyl
salt
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KR20130133078A (ko
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베뉘 방-안데르센
안드레 팔트
아르네 뫼르크
데 디고 헤이디 로페
레네 홀름
티네 브뤼안 스텐스뵐
로네 뮌크 링고르
마이클 제이 밀리
마이클 해롤드 락
외르겐 브로데르센
모르텐 외르겐센
니콜라스 무어
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하. 룬트벡 아크티에 셀스카브
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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KR1020137029366A 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진 Active KR101627901B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DKPA200600824 2006-06-16
DKPA200600824 2006-06-16
DKPA200601223 2006-09-22
DKPA200601223 2006-09-22
DKPA200601384 2006-10-25
DKPA200601384 2006-10-25
DKPA200700427 2007-03-20
DKPA200700427 2007-03-20
PCT/DK2007/050075 WO2007144005A1 (en) 2006-06-16 2007-06-15 1- [2- (2, 4-dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020087030668A Division KR20090028712A (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ｈｔ3 및 5-ｈｔ1ａ 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진

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Publication Number Publication Date
KR20130133078A KR20130133078A (ko) 2013-12-05
KR101627901B1 true KR101627901B1 (ko) 2016-06-13

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KR1020137029366A Active KR101627901B1 (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진
KR1020087030668A Ceased KR20090028712A (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ｈｔ3 및 5-ｈｔ1ａ 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진
KR1020137013877A Active KR101445514B1 (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진

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KR1020087030668A Ceased KR20090028712A (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ｈｔ3 및 5-ｈｔ1ａ 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진
KR1020137013877A Active KR101445514B1 (ko) 2006-06-16 2007-06-15 인지기능 장애의 치료를 위한, 세로토닌 재흡수, 5-ht3 및 5-ht1a 활성이 조합된 화합물로서의 1-[2-(2,4-디메틸페닐술파닐)-페닐]피페라진

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US (13) US8722684B2 (enExample)
EP (2) EP2439201B1 (enExample)
JP (8) JP4590013B2 (enExample)
KR (3) KR101627901B1 (enExample)
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