KR101588558B1 - 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제 - Google Patents

프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제 Download PDF

Info

Publication number
KR101588558B1
KR101588558B1 KR1020157002118A KR20157002118A KR101588558B1 KR 101588558 B1 KR101588558 B1 KR 101588558B1 KR 1020157002118 A KR1020157002118 A KR 1020157002118A KR 20157002118 A KR20157002118 A KR 20157002118A KR 101588558 B1 KR101588558 B1 KR 101588558B1
Authority
KR
South Korea
Prior art keywords
fat emulsion
alprostadil
amount
prostaglandin
emulsion
Prior art date
Application number
KR1020157002118A
Other languages
English (en)
Korean (ko)
Other versions
KR20150017775A (ko
Inventor
다카유키 후쿠야마
가즈히코 오자키
겐이치 히라이
Original Assignee
미쓰비시 타나베 파마 코퍼레이션
다이쇼 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 미쓰비시 타나베 파마 코퍼레이션, 다이쇼 세이야꾸 가부시끼가이샤 filed Critical 미쓰비시 타나베 파마 코퍼레이션
Publication of KR20150017775A publication Critical patent/KR20150017775A/ko
Application granted granted Critical
Publication of KR101588558B1 publication Critical patent/KR101588558B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020157002118A 2007-07-13 2008-07-11 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제 KR101588558B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2007-184358 2007-07-13
JP2007184358 2007-07-13
PCT/JP2008/001865 WO2009011112A1 (ja) 2007-07-13 2008-07-11 プロスタグランジンe1を含む安定な脂肪乳剤

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107002368A Division KR20100053541A (ko) 2007-07-13 2008-07-11 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제

Publications (2)

Publication Number Publication Date
KR20150017775A KR20150017775A (ko) 2015-02-17
KR101588558B1 true KR101588558B1 (ko) 2016-01-28

Family

ID=40259458

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020107002368A KR20100053541A (ko) 2007-07-13 2008-07-11 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제
KR1020157002118A KR101588558B1 (ko) 2007-07-13 2008-07-11 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020107002368A KR20100053541A (ko) 2007-07-13 2008-07-11 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제

Country Status (6)

Country Link
JP (2) JP5890599B2 (zh)
KR (2) KR20100053541A (zh)
CN (1) CN101743010A (zh)
MY (1) MY158088A (zh)
TW (1) TW200920379A (zh)
WO (1) WO2009011112A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102038639B (zh) * 2010-12-24 2012-05-02 海南碧凯药业有限公司 一种前列地尔注射制剂
CN102198095A (zh) * 2011-05-03 2011-09-28 北京中海康医药科技发展有限公司 一种依前列醇脂肪乳及其制备方法
JP5759804B2 (ja) * 2011-06-27 2015-08-05 富士フイルム株式会社 容器詰製剤
CN107519132A (zh) * 2017-08-29 2017-12-29 辅必成（上海）医药科技有限公司 一种前列地尔的纳米脂肪乳剂
WO2019230964A1 (ja) * 2018-05-31 2019-12-05 富士フイルム株式会社 容器詰水中油型乳化組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006188474A (ja) 2005-01-07 2006-07-20 Nichi-Iko Pharmaceutical Co Ltd 安定性に優れた脂肪乳剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2815595B2 (ja) * 1988-12-27 1998-10-27 松本製薬工業株式会社 医療用ガラス製品内表面の金属酸化物処理によるアルカリ等の溶出防止法
JP3268470B2 (ja) * 1992-11-18 2002-03-25 興亜硝子株式会社 溶出防止機能を有するガラス製品の製造方法
JPH0769897A (ja) * 1993-09-01 1995-03-14 Green Cross Corp:The 血中トリグリセリド低下作用剤
JPH07206472A (ja) * 1994-01-12 1995-08-08 Nippon Electric Glass Co Ltd 医薬用ホウケイ酸ガラス
JPH08104620A (ja) * 1994-10-05 1996-04-23 Green Cross Corp:The 薬物含有脂肪乳剤
JPH08175998A (ja) * 1994-12-19 1996-07-09 Takada Seiyaku Kk シリコート容器を用いた凍結乾燥製剤
JPH09235230A (ja) * 1995-12-29 1997-09-09 Hisamitsu Pharmaceut Co Inc イオントフォレーシス用製剤
WO1999009992A1 (fr) * 1997-08-27 1999-03-04 Yoshitomi Pharmaceutical Industries, Ltd. Promoteurs de neovascularisation
JP2001328612A (ja) * 2000-05-22 2001-11-27 Daiwa Tokushu Glass Kk 低アルカリガラス容器及びその製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006188474A (ja) 2005-01-07 2006-07-20 Nichi-Iko Pharmaceutical Co Ltd 安定性に優れた脂肪乳剤

Also Published As

Publication number Publication date
JP5890599B2 (ja) 2016-03-22
JP2014224131A (ja) 2014-12-04
JP5965944B2 (ja) 2016-08-10
KR20150017775A (ko) 2015-02-17
TW200920379A (en) 2009-05-16
WO2009011112A1 (ja) 2009-01-22
MY158088A (en) 2016-08-30
KR20100053541A (ko) 2010-05-20
JPWO2009011112A1 (ja) 2010-09-16
CN101743010A (zh) 2010-06-16

Similar Documents

Publication Publication Date Title
EP3248599B1 (en) Omega-3 fatty acid self-emulsifying composition
KR101588558B1 (ko) 프로스타글란딘 ｅ１을 포함하는 안정한 지방 유제
JP2021523909A (ja) 医薬製剤
KR102055937B1 (ko) 불용성 코르티코스테로이드 및 수용성 코르티코스테로이드를 포함하는 약학적 제형
KR101722398B1 (ko) ｐＨ 조절제를 포함하는 탁산의 약학적 용액 및 이의 제조 방법
JP5345744B1 (ja) 網膜疾患の予防、改善、又は治療剤
JP5193870B2 (ja) プロスタグランジン脂肪乳剤およびその製造方法、ならびにその安定化方法および乳化剤
US20210196826A1 (en) Biomaterial
US20210379098A1 (en) Biomaterial
JP2005516945A (ja) アゼチジン誘導体に基づく医薬組成物
CA3018670A1 (en) Viscoelastic gel of liraglutide adapted for once-weekly or once bi-weekly administration
JPH0566929B2 (zh)
CN114555056B (zh) 小分子PI4KIIIα抑制剂组合物、其制备方法及用途
AU2008326593A1 (en) Pyrazolone derivative emulsion formulations
JPH0881360A (ja) 安定な脂肪乳剤
KR20190110563A (ko) 지방 유제, 및 그 제조 방법, 지방 유제의 안정성을 향상시키는 방법, 그리고 지방 유제의 안정성 향상제
CN101632681B (zh) 甘油果糖脂质体药物组合物注射剂及制备方法
JP2013520435A (ja) タキサンのプロエマルジョン製剤ならびにその製造方法および使用
JPH04300833A (ja) プロスタグランジンｅ１　含有脂肪乳剤充填噴霧剤
JP2973077B2 (ja) ビタミンｅ製剤組成物
CN109985004A (zh) 氟比洛芬酯脂肪乳注射液、其制备方法及应用
JP2023522146A (ja) ホスファチジルコリンを含むヒマワリリン脂質組成物
WO2019230964A1 (ja) 容器詰水中油型乳化組成物
JPH04108732A (ja) Ｐａｆ拮抗剤含有脂肪乳剤
KR20170137117A (ko) 피부용의 의약 조성물

Legal Events

Date Code Title Description
A107 Divisional application of patent
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20181226

Year of fee payment: 4