KR101296479B1 - 심혈관 질환 치료를 위한 ｌ-카르니틴 및 글루코오스의용도 - Google Patents

심혈관 질환 치료를 위한 ｌ-카르니틴 및 글루코오스의용도 Download PDF

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Publication number
KR101296479B1
KR101296479B1 KR1020077000711A KR20077000711A KR101296479B1 KR 101296479 B1 KR101296479 B1 KR 101296479B1 KR 1020077000711 A KR1020077000711 A KR 1020077000711A KR 20077000711 A KR20077000711 A KR 20077000711A KR 101296479 B1 KR101296479 B1 KR 101296479B1
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KR
South Korea
Prior art keywords
carnitine
acid
infarction
pharmaceutical composition
glucose
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020077000711A
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English (en)
Korean (ko)
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KR20070039541A (ko
Inventor
알레아르도 코베레
Original Assignee
씨그마-토 인더스트리에 파마슈티체 리유니테 에스. 피. 에이.
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Publication of KR20070039541A publication Critical patent/KR20070039541A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077000711A 2004-07-13 2005-06-21 심혈관 질환 치료를 위한 ｌ-카르니틴 및 글루코오스의용도 Expired - Fee Related KR101296479B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2004A000346 2004-07-13
IT000346A ITRM20040346A1 (it) 2004-07-13 2004-07-13 Uso della l-carnitina per il trattamento di patologie cardiovascolari.
PCT/EP2005/006657 WO2006005415A2 (en) 2004-07-13 2005-06-21 Use of l-carnitine and glucose for the treatment of cardiovascular diseases

Publications (2)

Publication Number Publication Date
KR20070039541A KR20070039541A (ko) 2007-04-12
KR101296479B1 true KR101296479B1 (ko) 2013-08-13

Family

ID=34971575

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077000711A Expired - Fee Related KR101296479B1 (ko) 2004-07-13 2005-06-21 심혈관 질환 치료를 위한 ｌ-카르니틴 및 글루코오스의용도

Country Status (21)

Country Link
US (2) US7879908B2 (enExample)
EP (1) EP1773314B1 (enExample)
JP (1) JP5230195B2 (enExample)
KR (1) KR101296479B1 (enExample)
CN (2) CN101087602B (enExample)
AT (1) ATE542529T1 (enExample)
AU (1) AU2005262050B2 (enExample)
BR (1) BRPI0513303A8 (enExample)
CA (1) CA2569888C (enExample)
CY (1) CY1112686T1 (enExample)
DK (1) DK1773314T3 (enExample)
ES (1) ES2380913T3 (enExample)
HR (1) HRP20120178T1 (enExample)
IT (1) ITRM20040346A1 (enExample)
ME (1) ME01345B (enExample)
MX (1) MXPA06014665A (enExample)
PL (1) PL1773314T3 (enExample)
PT (1) PT1773314E (enExample)
RS (1) RS52253B (enExample)
SI (1) SI1773314T1 (enExample)
WO (1) WO2006005415A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR086543A1 (es) * 2011-05-25 2014-01-08 Bg Medicine Inc Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1120033B (it) * 1979-10-05 1986-03-19 Sigma Tau Ind Farmaceuti Composizione farmaceutica comprendente-carnitina adatta per l'alimentazione parenterale
JPS6415220A (en) 1987-07-06 1989-01-19 Mitsubishi Electric Corp Tension control device for utilizing maximum torque and maximum electric current of winding motor
JPH06102624B2 (ja) * 1990-08-10 1994-12-14 アース製薬株式会社 非心臓由来の不整脈防止薬
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
US5998386A (en) * 1997-09-19 1999-12-07 Feldman; Arthur M. Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue
WO2000030637A1 (en) * 1998-11-26 2000-06-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
KR100642731B1 (ko) * 1999-10-11 2006-11-03 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. 의료용 용액에서 삼투제로서 ｌ-카르니틴 및 그의알카노일 유도체의 용도
JP4674046B2 (ja) * 2002-04-01 2011-04-20 ザ ガバナーズ オブ ザ ユニバーシティ オブ アルバータ グルコース利用を刺激する化合物および使用方法
ITRM20030178A1 (it) 2003-04-17 2004-10-18 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Journal of the American College of Cardiology(1995), Vol. 26, No. 2, pp. 380-387 *
Journal of the American College of Cardiology(1995), Vol. 26, No. 2, pp. 380-387*
The American Journal of Cardiology(1996), Vol. 78, pp.476-479 *
The American Journal of Cardiology(1996), Vol. 78, pp.476-479*

Also Published As

Publication number Publication date
RS52253B (sr) 2012-10-31
ITRM20040346A1 (it) 2004-10-13
CN101087602B (zh) 2011-09-14
HK1166003A1 (zh) 2012-10-19
MXPA06014665A (es) 2007-03-12
ME01345B (me) 2012-10-31
CN102349923A (zh) 2012-02-15
HRP20120178T1 (hr) 2012-05-31
JP5230195B2 (ja) 2013-07-10
BRPI0513303A (pt) 2008-05-06
KR20070039541A (ko) 2007-04-12
WO2006005415A2 (en) 2006-01-19
ES2380913T3 (es) 2012-05-21
CA2569888C (en) 2013-08-13
CN102349923B (zh) 2016-04-27
US20070207970A1 (en) 2007-09-06
US8394854B2 (en) 2013-03-12
ATE542529T1 (de) 2012-02-15
PT1773314E (pt) 2012-03-29
AU2005262050B2 (en) 2011-02-24
DK1773314T3 (da) 2012-05-07
PL1773314T3 (pl) 2012-06-29
HK1113542A1 (en) 2008-10-10
AU2005262050A1 (en) 2006-01-19
EP1773314A2 (en) 2007-04-18
US7879908B2 (en) 2011-02-01
US20110086917A1 (en) 2011-04-14
CY1112686T1 (el) 2016-02-10
WO2006005415A3 (en) 2006-05-26
EP1773314B1 (en) 2012-01-25
CA2569888A1 (en) 2006-01-19
SI1773314T1 (sl) 2012-04-30
BRPI0513303A8 (pt) 2017-12-26
CN101087602A (zh) 2007-12-12
JP2008517872A (ja) 2008-05-29

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