HK1166003A1 - -肉鹼和葡萄糖治療心血管疾病的應用 - Google Patents
-肉鹼和葡萄糖治療心血管疾病的應用Info
- Publication number
- HK1166003A1 HK1166003A1 HK12106717.5A HK12106717A HK1166003A1 HK 1166003 A1 HK1166003 A1 HK 1166003A1 HK 12106717 A HK12106717 A HK 12106717A HK 1166003 A1 HK1166003 A1 HK 1166003A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- carnitine
- glucose
- treatment
- infarction
- grams
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 3
- 239000008103 glucose Substances 0.000 title abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title 1
- 229960001518 levocarnitine Drugs 0.000 title 1
- 206010061216 Infarction Diseases 0.000 abstract 2
- 206010000891 acute myocardial infarction Diseases 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 230000034994 death Effects 0.000 abstract 1
- 231100000517 death Toxicity 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000346A ITRM20040346A1 (it) | 2004-07-13 | 2004-07-13 | Uso della l-carnitina per il trattamento di patologie cardiovascolari. |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1166003A1 true HK1166003A1 (zh) | 2012-10-19 |
Family
ID=34971575
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08102916.9A HK1113542A1 (en) | 2004-07-13 | 2008-03-13 | Use of l-carnitine and glucose for the treatment of cardiovascular diseases l- |
HK12106717.5A HK1166003A1 (zh) | 2004-07-13 | 2012-07-10 | -肉鹼和葡萄糖治療心血管疾病的應用 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08102916.9A HK1113542A1 (en) | 2004-07-13 | 2008-03-13 | Use of l-carnitine and glucose for the treatment of cardiovascular diseases l- |
Country Status (22)
Country | Link |
---|---|
US (2) | US7879908B2 (zh) |
EP (1) | EP1773314B1 (zh) |
JP (1) | JP5230195B2 (zh) |
KR (1) | KR101296479B1 (zh) |
CN (2) | CN101087602B (zh) |
AT (1) | ATE542529T1 (zh) |
AU (1) | AU2005262050B2 (zh) |
BR (1) | BRPI0513303A8 (zh) |
CA (1) | CA2569888C (zh) |
CY (1) | CY1112686T1 (zh) |
DK (1) | DK1773314T3 (zh) |
ES (1) | ES2380913T3 (zh) |
HK (2) | HK1113542A1 (zh) |
HR (1) | HRP20120178T1 (zh) |
IT (1) | ITRM20040346A1 (zh) |
ME (1) | ME01345B (zh) |
MX (1) | MXPA06014665A (zh) |
PL (1) | PL1773314T3 (zh) |
PT (1) | PT1773314E (zh) |
RS (1) | RS52253B (zh) |
SI (1) | SI1773314T1 (zh) |
WO (1) | WO2006005415A2 (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR086543A1 (es) * | 2011-05-25 | 2014-01-08 | Bg Medicine Inc | Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1120033B (it) * | 1979-10-05 | 1986-03-19 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica comprendente-carnitina adatta per l'alimentazione parenterale |
JPS6415220A (en) | 1987-07-06 | 1989-01-19 | Mitsubishi Electric Corp | Tension control device for utilizing maximum torque and maximum electric current of winding motor |
JPH06102624B2 (ja) * | 1990-08-10 | 1994-12-14 | アース製薬株式会社 | 非心臓由来の不整脈防止薬 |
IT1261695B (it) * | 1993-06-02 | 1996-05-29 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
US5998386A (en) * | 1997-09-19 | 1999-12-07 | Feldman; Arthur M. | Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue |
WO2000030637A1 (en) * | 1998-11-26 | 2000-06-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia |
ATE336243T1 (de) * | 1999-10-11 | 2006-09-15 | Sigma Tau Ind Farmaceuti | Verwendung von l-carnitin und seinen alkanoyl- derivaten als osmotisches mittel in lösungen für medizinische verwendung |
WO2003082800A1 (en) * | 2002-04-01 | 2003-10-09 | The University Of Alberta | Compounds that stimulate glucose utilization and methods of use |
ITRM20030178A1 (it) * | 2003-04-17 | 2004-10-18 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina per il trattamento di patologie cardiovascolari. |
-
2004
- 2004-07-13 IT IT000346A patent/ITRM20040346A1/it unknown
-
2005
- 2005-06-21 EP EP05755616A patent/EP1773314B1/en active Active
- 2005-06-21 US US11/629,202 patent/US7879908B2/en active Active
- 2005-06-21 AT AT05755616T patent/ATE542529T1/de active
- 2005-06-21 BR BRPI0513303A patent/BRPI0513303A8/pt not_active Application Discontinuation
- 2005-06-21 CN CN2005800234751A patent/CN101087602B/zh not_active Expired - Fee Related
- 2005-06-21 ES ES05755616T patent/ES2380913T3/es active Active
- 2005-06-21 JP JP2007520688A patent/JP5230195B2/ja not_active Expired - Fee Related
- 2005-06-21 SI SI200531481T patent/SI1773314T1/sl unknown
- 2005-06-21 CN CN201110226409.1A patent/CN102349923B/zh not_active Expired - Fee Related
- 2005-06-21 PL PL05755616T patent/PL1773314T3/pl unknown
- 2005-06-21 DK DK05755616.9T patent/DK1773314T3/da active
- 2005-06-21 WO PCT/EP2005/006657 patent/WO2006005415A2/en active Application Filing
- 2005-06-21 CA CA2569888A patent/CA2569888C/en active Active
- 2005-06-21 RS RS20120095A patent/RS52253B/en unknown
- 2005-06-21 PT PT05755616T patent/PT1773314E/pt unknown
- 2005-06-21 AU AU2005262050A patent/AU2005262050B2/en not_active Ceased
- 2005-06-21 KR KR1020077000711A patent/KR101296479B1/ko active IP Right Grant
- 2005-06-21 MX MXPA06014665A patent/MXPA06014665A/es not_active Application Discontinuation
- 2005-06-21 ME MEP-2012-32A patent/ME01345B/me unknown
-
2008
- 2008-03-13 HK HK08102916.9A patent/HK1113542A1/xx not_active IP Right Cessation
-
2010
- 2010-12-20 US US12/972,617 patent/US8394854B2/en active Active
-
2012
- 2012-02-22 HR HRP20120178TT patent/HRP20120178T1/hr unknown
- 2012-04-05 CY CY20121100341T patent/CY1112686T1/el unknown
- 2012-07-10 HK HK12106717.5A patent/HK1166003A1/zh not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230615 |