KR101254615B1 - 색소 침착 예방 또는 개선용 조성물 - Google Patents

색소 침착 예방 또는 개선용 조성물 Download PDF

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Publication number
KR101254615B1
KR101254615B1 KR1020077007652A KR20077007652A KR101254615B1 KR 101254615 B1 KR101254615 B1 KR 101254615B1 KR 1020077007652 A KR1020077007652 A KR 1020077007652A KR 20077007652 A KR20077007652 A KR 20077007652A KR 101254615 B1 KR101254615 B1 KR 101254615B1
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South Korea
Prior art keywords
pigmentation
acid
component
composition
test example
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Expired - Lifetime
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KR1020077007652A
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Korean (ko)
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KR20070100226A (ko
Inventor
후미키 하라노
시게오 시노하라
마사히코 다나카
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오츠카 세이야쿠 가부시키가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020077007652A 2004-09-22 2005-09-21 색소 침착 예방 또는 개선용 조성물 Expired - Lifetime KR101254615B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JPJP-P-2004-00274454 2004-09-22
JP2004274454 2004-09-22
JPJP-P-2004-00376562 2004-12-27
JP2004376562 2004-12-27
JPJP-P-2005-00194428 2005-07-01
JP2005194428A JP5093998B2 (ja) 2004-09-22 2005-07-01 色素沈着予防又は改善剤
PCT/JP2005/017363 WO2006033343A1 (ja) 2004-09-22 2005-09-21 色素沈着予防又は改善用組成物

Publications (2)

Publication Number Publication Date
KR20070100226A KR20070100226A (ko) 2007-10-10
KR101254615B1 true KR101254615B1 (ko) 2013-04-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077007652A Expired - Lifetime KR101254615B1 (ko) 2004-09-22 2005-09-21 색소 침착 예방 또는 개선용 조성물

Country Status (11)

Country Link
US (1) US20080260878A1 (enExample)
EP (1) EP1806120B1 (enExample)
JP (1) JP5093998B2 (enExample)
KR (1) KR101254615B1 (enExample)
CN (1) CN101027032B (enExample)
AU (1) AU2005285903B2 (enExample)
BR (1) BRPI0515585A (enExample)
CA (1) CA2580147C (enExample)
ES (1) ES2421606T3 (enExample)
TW (1) TWI359662B (enExample)
WO (1) WO2006033343A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190043738A (ko) * 2017-10-19 2019-04-29 주식회사 삼성인터네셔널 기미 개선용 화장료 조성물

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HRP20130459T1 (en) 2004-01-22 2013-06-30 University Of Miami Topical co-enzyme q10 formulations and methods of use
JP5514268B2 (ja) * 2004-09-22 2014-06-04 大塚製薬株式会社 色素沈着予防又は改善剤
JP5015620B2 (ja) * 2007-01-30 2012-08-29 株式会社クラレ 皮膚外用剤
JP6058263B2 (ja) 2008-04-11 2017-01-11 バーグ リミテッド ライアビリティ カンパニー 癌細胞においてアポトーシスを誘導する方法および使用
JP5263940B2 (ja) * 2008-05-29 2013-08-14 株式会社 資生堂 皮膚外用剤
CN102481269B (zh) 2009-05-11 2015-10-07 博格有限责任公司 包含辅酶q10的药物组合物及其制备方法
JP5748961B2 (ja) * 2010-03-19 2015-07-15 ポーラ化成工業株式会社 組成物
KR20130120450A (ko) 2010-06-25 2013-11-04 오츠카 세이야쿠 가부시키가이샤 광 노출에 의한 비정상적인 피부 세포 형성 억제제
US20130129651A1 (en) * 2010-08-03 2013-05-23 Hayashibara Co., Ltd. Agent for enhancing the effect of skin-whitening ingredients and uses thereof
JP6092844B2 (ja) 2011-04-04 2017-03-08 バーグ エルエルシー 中枢神経系腫瘍の治療方法
CN102813642A (zh) * 2012-09-13 2012-12-12 中南大学湘雅二医院 一种祛斑抗皮肤衰老的复方制剂
JP6166544B2 (ja) * 2013-02-13 2017-07-19 第一三共ヘルスケア株式会社 色素沈着症の予防又は治療剤
CA2908041C (en) 2013-04-04 2018-05-01 Hyundai Pharm Co., Ltd. Composition for external use preparation with improved transdermal permeability
BR112015025424A2 (pt) 2013-04-08 2017-07-18 Berg Llc tratamento de câncer usando terapias de combinação de coenzima q10
MX381399B (es) 2013-09-04 2025-03-12 Berg Llc Formulaciones de coenzima q10 y métodos de uso.
WO2017087576A1 (en) 2015-11-16 2017-05-26 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10
JP7675501B2 (ja) 2017-04-04 2025-05-13 アンタイ－プラスミン テクノロジーズ， エルエルシー 非外科的治療を向上させる方法
US20200375867A1 (en) * 2018-01-31 2020-12-03 Otsuka Pharmaceutical Co., Ltd. Method for suppressing discoloration of external composition containing adenosine phosphate and tranexamic acid
CN111840417A (zh) * 2019-04-30 2020-10-30 成都铜雀台医学美容医院有限公司 一种治疗黄褐斑的针剂、其制备方法及应用
WO2021229533A1 (en) * 2020-05-14 2021-11-18 Palani Llc A fatty acid based composition for treatment and/or prevention of enveloped-virus related infections
WO2022216577A1 (en) * 2021-04-09 2022-10-13 Merck Sharp & Dohme Llc Novel forms of cyclic dinucleotide compounds
KR102726678B1 (ko) * 2022-04-20 2024-11-07 주식회사 바른바름 4-알킬레졸시놀을 포함하는 고체지질 나노입자, 이를 포함하는 화장료 조성물 및 화장품

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JPH0648934A (ja) * 1992-06-02 1994-02-22 Sansho Seiyaku Co Ltd 皮膚外用剤
WO2004016238A1 (ja) * 2002-08-06 2004-02-26 Otsuka Pharmaceutical Co., Ltd. 老化防止用組成物

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JPH0648934A (ja) * 1992-06-02 1994-02-22 Sansho Seiyaku Co Ltd 皮膚外用剤
WO2004016238A1 (ja) * 2002-08-06 2004-02-26 Otsuka Pharmaceutical Co., Ltd. 老化防止用組成物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190043738A (ko) * 2017-10-19 2019-04-29 주식회사 삼성인터네셔널 기미 개선용 화장료 조성물
KR102014602B1 (ko) * 2017-10-19 2019-08-29 주식회사 삼성인터네셔널 기미 개선용 화장료 조성물

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Publication number Publication date
JP2006206575A (ja) 2006-08-10
CN101027032A (zh) 2007-08-29
US20080260878A1 (en) 2008-10-23
TWI359662B (enExample) 2012-03-11
CA2580147C (en) 2013-01-22
CN101027032B (zh) 2010-11-24
KR20070100226A (ko) 2007-10-10
HK1105859A1 (en) 2008-02-29
EP1806120A1 (en) 2007-07-11
BRPI0515585A (pt) 2008-07-29
EP1806120A4 (en) 2009-01-28
JP5093998B2 (ja) 2012-12-12
AU2005285903B2 (en) 2011-03-03
ES2421606T3 (es) 2013-09-04
WO2006033343A1 (ja) 2006-03-30
AU2005285903A1 (en) 2006-03-30
EP1806120B1 (en) 2013-05-22
CA2580147A1 (en) 2006-03-30

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