KR101102475B1 - 금속 촉매의 함유량이 적은 생체내 분해흡수성 고분자 및 그 제조 방법 - Google Patents

금속 촉매의 함유량이 적은 생체내 분해흡수성 고분자 및 그 제조 방법 Download PDF

Info

Publication number
KR101102475B1
KR101102475B1 KR1020087029690A KR20087029690A KR101102475B1 KR 101102475 B1 KR101102475 B1 KR 101102475B1 KR 1020087029690 A KR1020087029690 A KR 1020087029690A KR 20087029690 A KR20087029690 A KR 20087029690A KR 101102475 B1 KR101102475 B1 KR 101102475B1
Authority
KR
South Korea
Prior art keywords
metal catalyst
copolymer
absorbent polymer
washing
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020087029690A
Other languages
English (en)
Korean (ko)
Other versions
KR20090023599A (ko
Inventor
히데토시 아리무라
요시타케 토카하시
코지 야마우치
Original Assignee
군제 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2006178808A external-priority patent/JP5354844B2/ja
Priority claimed from JP2006178805A external-priority patent/JP5334360B2/ja
Application filed by 군제 가부시키가이샤 filed Critical 군제 가부시키가이샤
Publication of KR20090023599A publication Critical patent/KR20090023599A/ko
Application granted granted Critical
Publication of KR101102475B1 publication Critical patent/KR101102475B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78Preparation processes
    • C08G63/82Preparation processes characterised by the catalyst used
    • C08G63/823Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06At least partially resorbable materials
    • A61L17/10At least partially resorbable materials containing macromolecular materials
    • A61L17/12Homopolymers or copolymers of glycolic acid or lactic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78Preparation processes
    • C08G63/82Preparation processes characterised by the catalyst used
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/90Purification; Drying
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00Compositions of unspecified macromolecular compounds
    • C08L101/16Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
KR1020087029690A 2006-06-28 2007-06-18 금속 촉매의 함유량이 적은 생체내 분해흡수성 고분자 및 그 제조 방법 Expired - Fee Related KR101102475B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JPJP-P-2006-178808 2006-06-28
JP2006178808A JP5354844B2 (ja) 2006-06-28 2006-06-28 金属触媒の含有量が少ない生体内分解吸収性高分子の製法
JPJP-P-2006-178805 2006-06-28
JP2006178805A JP5334360B2 (ja) 2006-06-28 2006-06-28 金属触媒の含有量が少ない生体内分解吸収性高分子の製法
PCT/JP2007/062212 WO2008001633A1 (fr) 2006-06-28 2007-06-18 Polymère biodégradable/absorbable à teneur en catalyseur métallique réduite, et procédé de production

Publications (2)

Publication Number Publication Date
KR20090023599A KR20090023599A (ko) 2009-03-05
KR101102475B1 true KR101102475B1 (ko) 2012-01-05

Family

ID=38845401

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087029690A Expired - Fee Related KR101102475B1 (ko) 2006-06-28 2007-06-18 금속 촉매의 함유량이 적은 생체내 분해흡수성 고분자 및 그 제조 방법

Country Status (10)

Country Link
US (2) US20090171064A1 (enExample)
EP (1) EP2039714B1 (enExample)
KR (1) KR101102475B1 (enExample)
AU (1) AU2007264560B2 (enExample)
BR (1) BRPI0713060A2 (enExample)
CA (1) CA2653295C (enExample)
IN (1) IN2014DN10439A (enExample)
NZ (1) NZ573125A (enExample)
TW (1) TWI440651B (enExample)
WO (1) WO2008001633A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
CA2619571A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
US20090274742A1 (en) * 2005-08-18 2009-11-05 Brown Malcolm Nmi Multimodal high strength devices and composites
CN101594831B (zh) 2006-11-30 2011-09-14 史密夫和内修有限公司 纤维增强的复合材料
JP5416090B2 (ja) 2007-04-18 2014-02-12 スミス アンド ネフュー ピーエルシー 形状記憶ポリマーの膨張成形
AU2008243035B2 (en) 2007-04-19 2013-09-12 Smith & Nephew, Inc. Graft fixation
JP5520814B2 (ja) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッド マルチモーダル形状記憶ポリマー
GB0715376D0 (en) * 2007-08-07 2007-09-19 Smith & Nephew Coating
EP2985302B1 (en) 2013-04-12 2018-01-10 National University Corporation Kyoto Institute of Technology Method for producing lactide-lactone copolymer
CN104983484B (zh) * 2015-05-26 2018-07-24 无锡市第二人民医院 一种经导管植入高弹性外支架可降解的生物瓣膜系统及制备和应用
SG11202001688WA (en) * 2017-08-31 2020-03-30 Evonik Corp Improved resorbable polymer purification process
GB2568526A (en) * 2017-11-20 2019-05-22 Rebio Tech Oy Composition
EP3887425A1 (en) 2018-11-27 2021-10-06 Evonik Operations GmbH Process for preparing a resorbable polyester as a granulate or powder by bulk polymerization
CN112940234B (zh) * 2021-01-28 2022-05-03 广东粤港澳大湾区黄埔材料研究院 一种高纯度聚乙丙交酯的制备方法
WO2022221904A1 (en) 2021-04-20 2022-10-27 Waterco Limited Multi-cyclone sediment filter
KR20240114490A (ko) * 2023-01-17 2024-07-24 한국화학연구원 불소기능화 생분해성 고분자, 이의 제조방법 및 이를 이용한 표면 코팅

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06116381A (ja) * 1992-10-09 1994-04-26 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸の精製方法
JPH07102053A (ja) * 1992-10-09 1995-04-18 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸およびその精製方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4643734A (en) 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
NL9001984A (nl) * 1990-09-10 1992-04-01 Stamicarbon Werkwijze voor het produceren van een voorwerp van een copolymeer van lactide en epsilon-caprolacton voor medische toepassingen.
IT1249045B (it) * 1991-02-21 1995-02-11 Himont Inc Processo per la sintesi allo stato solido di polimeri dell'acido lattico e prodotti cosi ottenuti
JP3273821B2 (ja) * 1993-03-02 2002-04-15 三井化学株式会社 ポリヒドロキシカルボン酸の精製法
JP3622327B2 (ja) * 1996-03-28 2005-02-23 トヨタ自動車株式会社 脂肪族ポリエステルのペレットの洗浄方法
JP3453648B2 (ja) 1998-12-26 2003-10-06 株式会社ビーエムジー 金属含有量が少ない生体内分解吸収性高分子およびその製造方法。
EP1334990A1 (en) * 2002-02-06 2003-08-13 Polyganics B.V. DL-Lactide-epsilon-caprolactone copolymers
JP4659451B2 (ja) * 2004-12-28 2011-03-30 グンゼ株式会社 金属触媒の含有量が少ない生体内分解吸収性高分子及びその製法
JP2007070413A (ja) * 2005-09-05 2007-03-22 Teijin Ltd ポリ乳酸組成物およびその製造方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06116381A (ja) * 1992-10-09 1994-04-26 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸の精製方法
JPH07102053A (ja) * 1992-10-09 1995-04-18 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸およびその精製方法

Also Published As

Publication number Publication date
US20090171064A1 (en) 2009-07-02
US8481673B2 (en) 2013-07-09
AU2007264560A1 (en) 2008-01-03
TW200806704A (en) 2008-02-01
US20130066042A1 (en) 2013-03-14
AU2007264560B2 (en) 2011-12-01
CA2653295C (en) 2014-03-11
WO2008001633A1 (fr) 2008-01-03
CA2653295A1 (en) 2008-01-03
TWI440651B (zh) 2014-06-11
BRPI0713060A2 (pt) 2012-04-10
EP2039714A1 (en) 2009-03-25
KR20090023599A (ko) 2009-03-05
HK1129123A1 (en) 2009-11-20
EP2039714A4 (en) 2010-12-29
EP2039714B1 (en) 2015-03-04
IN2014DN10439A (enExample) 2015-08-21
NZ573125A (en) 2011-12-22

Similar Documents

Publication Publication Date Title
KR101102475B1 (ko) 금속 촉매의 함유량이 적은 생체내 분해흡수성 고분자 및 그 제조 방법
US7217744B2 (en) Polymeric networks
KR100696407B1 (ko) 폴리(프로필렌 푸마레이트)-디아크릴레이트 마크로머와가교결합된 생분해성 폴리(프로필렌 푸마레이트) 네트워크
AU2006271727B2 (en) Resorbable polyether esters for producing medical implants
EP1472301B1 (en) DL−LACTIDE−&Egr;−CAPROLACTONE COPOLYMERS
JPH03157422A (ja) 変性ポリエステル樹脂組成物、その製造方法、およびその用途
JP4659451B2 (ja) 金属触媒の含有量が少ない生体内分解吸収性高分子及びその製法
JP6017580B2 (ja) 生分解性高分子化合物
CN113583412A (zh) 一种改性聚乳酸材料及其制备方法和应用
CN101466758B (zh) 具有较低的金属催化剂含量的生物可降解的及生物可吸收的聚合物及其制备方法
EP1516006B1 (en) Block copolymers for surgical articles
JP5208184B2 (ja) 金属触媒の含有量が少ない生体内分解吸収性高分子及びその製法
JP2009132769A (ja) 医療用インプラント用ラクチド/ε−カプロラクトン共重合体
JP5354844B2 (ja) 金属触媒の含有量が少ない生体内分解吸収性高分子の製法
HK1129123B (en) Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof
Xie et al. Novel injectable and in situ curable glycolide/lactide based biodegradable polymer resins and composites
JP2003306543A (ja) トリメチレンカーボネート重合体及びその製造方法並びにこれを用いて成形した生体材料
KR20210067089A (ko) 생분해성 블록 공중합체 및 그 제조방법

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20141229

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20141229