CA2653295C - Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof - Google Patents

Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof Download PDF

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Publication number
CA2653295C
CA2653295C CA2653295A CA2653295A CA2653295C CA 2653295 C CA2653295 C CA 2653295C CA 2653295 A CA2653295 A CA 2653295A CA 2653295 A CA2653295 A CA 2653295A CA 2653295 C CA2653295 C CA 2653295C
Authority
CA
Canada
Prior art keywords
copolymer
metal catalyst
washing
polymer
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2653295A
Other languages
English (en)
French (fr)
Other versions
CA2653295A1 (en
Inventor
Hidetoshi Arimura
Yoshitake Takahashi
Koji Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gunze Ltd
Original Assignee
Gunze Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2006178808A external-priority patent/JP5354844B2/ja
Priority claimed from JP2006178805A external-priority patent/JP5334360B2/ja
Application filed by Gunze Ltd filed Critical Gunze Ltd
Publication of CA2653295A1 publication Critical patent/CA2653295A1/en
Application granted granted Critical
Publication of CA2653295C publication Critical patent/CA2653295C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/90—Purification; Drying
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/16—Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
CA2653295A 2006-06-28 2007-06-18 Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof Expired - Fee Related CA2653295C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2006-178808 2006-06-28
JP2006-178805 2006-06-28
JP2006178808A JP5354844B2 (ja) 2006-06-28 2006-06-28 金属触媒の含有量が少ない生体内分解吸収性高分子の製法
JP2006178805A JP5334360B2 (ja) 2006-06-28 2006-06-28 金属触媒の含有量が少ない生体内分解吸収性高分子の製法
PCT/JP2007/062212 WO2008001633A1 (fr) 2006-06-28 2007-06-18 Polymère biodégradable/absorbable à teneur en catalyseur métallique réduite, et procédé de production

Publications (2)

Publication Number Publication Date
CA2653295A1 CA2653295A1 (en) 2008-01-03
CA2653295C true CA2653295C (en) 2014-03-11

Family

ID=38845401

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2653295A Expired - Fee Related CA2653295C (en) 2006-06-28 2007-06-18 Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof

Country Status (10)

Country Link
US (2) US20090171064A1 (enExample)
EP (1) EP2039714B1 (enExample)
KR (1) KR101102475B1 (enExample)
AU (1) AU2007264560B2 (enExample)
BR (1) BRPI0713060A2 (enExample)
CA (1) CA2653295C (enExample)
IN (1) IN2014DN10439A (enExample)
NZ (1) NZ573125A (enExample)
TW (1) TWI440651B (enExample)
WO (1) WO2008001633A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
CA2619552A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc Multimodal high strength devices and composites
JP2009504929A (ja) * 2005-08-18 2009-02-05 スミス アンド ネフュー ピーエルシー 高強度デバイス及び複合材料
AU2007325001B2 (en) 2006-11-30 2014-04-10 Smith & Nephew, Inc. Fiber reinforced composite material
US9815240B2 (en) 2007-04-18 2017-11-14 Smith & Nephew, Inc. Expansion moulding of shape memory polymers
US9770534B2 (en) 2007-04-19 2017-09-26 Smith & Nephew, Inc. Graft fixation
ATE547129T1 (de) 2007-04-19 2012-03-15 Smith & Nephew Inc Multimodale formgedächtnis-polymere
GB0715376D0 (en) * 2007-08-07 2007-09-19 Smith & Nephew Coating
WO2014167966A1 (ja) 2013-04-12 2014-10-16 国立大学法人京都工芸繊維大学 ラクチド－ラクトン共重合体の製造方法
CN104983484B (zh) * 2015-05-26 2018-07-24 无锡市第二人民医院 一种经导管植入高弹性外支架可降解的生物瓣膜系统及制备和应用
IL272809B2 (en) * 2017-08-31 2025-05-01 Evonik Corp Improved resorbable polymer purification process
GB2568526A (en) * 2017-11-20 2019-05-22 Rebio Tech Oy Composition
KR102884866B1 (ko) * 2018-11-27 2025-11-13 에보니크 오퍼레이션즈 게엠베하 벌크 중합에 의한 과립 또는 분말로서의 재흡수성 폴리에스테르의 제조 방법
CN112940234B (zh) * 2021-01-28 2022-05-03 广东粤港澳大湾区黄埔材料研究院 一种高纯度聚乙丙交酯的制备方法
EP4326445A4 (en) 2021-04-20 2025-03-26 Waterco Limited MULTI-CYCLODE SEDIMENT FILTER
KR102923800B1 (ko) * 2023-01-17 2026-02-04 한국화학연구원 불소기능화 생분해성 고분자, 이의 제조방법 및 이를 이용한 표면 코팅

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4643734A (en) 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
NL9001984A (nl) 1990-09-10 1992-04-01 Stamicarbon Werkwijze voor het produceren van een voorwerp van een copolymeer van lactide en epsilon-caprolacton voor medische toepassingen.
IT1249045B (it) * 1991-02-21 1995-02-11 Himont Inc Processo per la sintesi allo stato solido di polimeri dell'acido lattico e prodotti cosi ottenuti
JPH06116381A (ja) * 1992-10-09 1994-04-26 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸の精製方法
JP3184680B2 (ja) * 1992-10-09 2001-07-09 三井化学株式会社 ポリヒドロキシカルボン酸の精製方法
JP3273821B2 (ja) * 1993-03-02 2002-04-15 三井化学株式会社 ポリヒドロキシカルボン酸の精製法
JP3622327B2 (ja) * 1996-03-28 2005-02-23 トヨタ自動車株式会社 脂肪族ポリエステルのペレットの洗浄方法
JP3453648B2 (ja) 1998-12-26 2003-10-06 株式会社ビーエムジー 金属含有量が少ない生体内分解吸収性高分子およびその製造方法。
EP1334990A1 (en) * 2002-02-06 2003-08-13 Polyganics B.V. DL-Lactide-epsilon-caprolactone copolymers
JP4659451B2 (ja) * 2004-12-28 2011-03-30 グンゼ株式会社 金属触媒の含有量が少ない生体内分解吸収性高分子及びその製法
JP2007070413A (ja) * 2005-09-05 2007-03-22 Teijin Ltd ポリ乳酸組成物およびその製造方法

Also Published As

Publication number Publication date
EP2039714A4 (en) 2010-12-29
CA2653295A1 (en) 2008-01-03
NZ573125A (en) 2011-12-22
AU2007264560A1 (en) 2008-01-03
KR101102475B1 (ko) 2012-01-05
WO2008001633A1 (fr) 2008-01-03
US20130066042A1 (en) 2013-03-14
US8481673B2 (en) 2013-07-09
TWI440651B (zh) 2014-06-11
IN2014DN10439A (enExample) 2015-08-21
HK1129123A1 (en) 2009-11-20
EP2039714B1 (en) 2015-03-04
EP2039714A1 (en) 2009-03-25
KR20090023599A (ko) 2009-03-05
BRPI0713060A2 (pt) 2012-04-10
TW200806704A (en) 2008-02-01
AU2007264560B2 (en) 2011-12-01
US20090171064A1 (en) 2009-07-02

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Effective date: 20170619