KR101006594B1 - 안정한 아데노바이러스 벡터 및 그 증식 방법 - Google Patents

안정한 아데노바이러스 벡터 및 그 증식 방법 Download PDF

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KR101006594B1
KR101006594B1 KR1020047016964A KR20047016964A KR101006594B1 KR 101006594 B1 KR101006594 B1 KR 101006594B1 KR 1020047016964 A KR1020047016964 A KR 1020047016964A KR 20047016964 A KR20047016964 A KR 20047016964A KR 101006594 B1 KR101006594 B1 KR 101006594B1
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adenovirus
pix
sequence
promoter
recombinant
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KR20040106365A (ko
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로날드 포헬스
멘조 얀스 엠코 하펜하
다비드 아드리아누스 테오도루스 자위듀헤이스트
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크루셀 홀란드 비.브이.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Lubricants (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020047016964A 2002-04-25 2003-04-24 안정한 아데노바이러스 벡터 및 그 증식 방법 Expired - Fee Related KR101006594B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
NLPCT/NL02/00281 2002-04-25
NL0200281 2002-04-25
NL0200656 2002-10-15
NLPCT/NL02/00656 2002-10-15
EP02102631 2002-11-25
EP02102631.5 2002-11-25
PCT/EP2003/050126 WO2004001032A2 (en) 2002-04-25 2003-04-24 Stable adenoviral vectors and methods for propagation thereof

Publications (2)

Publication Number Publication Date
KR20040106365A KR20040106365A (ko) 2004-12-17
KR101006594B1 true KR101006594B1 (ko) 2011-01-07

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KR1020047016964A Expired - Fee Related KR101006594B1 (ko) 2002-04-25 2003-04-24 안정한 아데노바이러스 벡터 및 그 증식 방법

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US (2) US7285265B2 (https=)
EP (1) EP1497440B1 (https=)
JP (1) JP4495588B2 (https=)
KR (1) KR101006594B1 (https=)
CN (1) CN100374574C (https=)
AT (1) ATE405663T1 (https=)
AU (1) AU2003271738C1 (https=)
CA (1) CA2478508C (https=)
DE (1) DE60323080D1 (https=)
DK (1) DK1497440T3 (https=)
ES (1) ES2310247T3 (https=)
IL (1) IL164802A0 (https=)
NO (1) NO334299B1 (https=)
NZ (1) NZ534865A (https=)
PL (1) PL208588B1 (https=)
SI (1) SI1497440T1 (https=)
WO (1) WO2004001032A2 (https=)

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CA2478508A1 (en) 2003-12-31
WO2004001032A2 (en) 2003-12-31
HK1069185A1 (en) 2005-05-13
CA2478508C (en) 2013-07-02
DK1497440T3 (da) 2008-12-01
NO334299B1 (no) 2014-02-03
CN100374574C (zh) 2008-03-12
EP1497440B1 (en) 2008-08-20
US20050163753A1 (en) 2005-07-28
US7285265B2 (en) 2007-10-23
CN1650021A (zh) 2005-08-03
JP2005523730A (ja) 2005-08-11
KR20040106365A (ko) 2004-12-17
NZ534865A (en) 2008-07-31
US20080206837A1 (en) 2008-08-28
PL208588B1 (pl) 2011-05-31
ATE405663T1 (de) 2008-09-15
AU2003271738A1 (en) 2004-01-06
AU2003271738B2 (en) 2007-10-11
AU2003271738C1 (en) 2008-04-17
US8052967B2 (en) 2011-11-08
NO20045131L (no) 2005-01-21
DE60323080D1 (de) 2008-10-02
ES2310247T3 (es) 2009-01-01
EP1497440A2 (en) 2005-01-19
WO2004001032A3 (en) 2004-04-01
SI1497440T1 (sl) 2009-02-28
IL164802A0 (en) 2005-12-18
PL373337A1 (en) 2005-08-22
JP4495588B2 (ja) 2010-07-07

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