KR100967277B1 - 퀴놀린 및 이소퀴놀린 유도체, 그의 제조 방법 및항염증제로서의 그의 용도 - Google Patents

퀴놀린 및 이소퀴놀린 유도체, 그의 제조 방법 및항염증제로서의 그의 용도 Download PDF

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KR100967277B1
KR100967277B1 KR1020047015697A KR20047015697A KR100967277B1 KR 100967277 B1 KR100967277 B1 KR 100967277B1 KR 1020047015697 A KR1020047015697 A KR 1020047015697A KR 20047015697 A KR20047015697 A KR 20047015697A KR 100967277 B1 KR100967277 B1 KR 100967277B1
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methyl
group
trifluoromethyl
formula
mmol
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Korean (ko)
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KR20040097268A (ko
Inventor
스테판 야로호
만프레트 레만
노르베르트 슈미스
마르쿠스 베르거
하르트무트 레빙켈
콘라트 크롤리키비츠
베르너 스쿠발라
하이케 슈에케
아른트 쇼텔리우스
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바이엘 쉐링 파마 악티엔게젤샤프트
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
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    • C—CHEMISTRY; METALLURGY
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
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    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Endocrinology (AREA)
  • Cardiology (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020047015697A 2002-04-02 2003-03-29 퀴놀린 및 이소퀴놀린 유도체, 그의 제조 방법 및항염증제로서의 그의 용도 Expired - Fee Related KR100967277B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10215316.7 2002-04-02
DE10215316A DE10215316C1 (de) 2002-04-02 2002-04-02 Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer
PCT/EP2003/003298 WO2003082827A1 (de) 2002-04-02 2003-03-29 Chinolin- und isochinolin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer

Publications (2)

Publication Number Publication Date
KR20040097268A KR20040097268A (ko) 2004-11-17
KR100967277B1 true KR100967277B1 (ko) 2010-07-01

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US (1) US7329753B2 (enExample)
EP (1) EP1492771B1 (enExample)
JP (1) JP4593929B2 (enExample)
KR (1) KR100967277B1 (enExample)
CN (1) CN1659144B (enExample)
AR (1) AR039222A1 (enExample)
AT (1) ATE355277T1 (enExample)
AU (1) AU2003215678B2 (enExample)
BR (1) BR0308967A (enExample)
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DE (2) DE10215316C1 (enExample)
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EA (1) EA008540B1 (enExample)
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IL (1) IL164292A (enExample)
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MX (1) MXPA04009684A (enExample)
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NZ (1) NZ535872A (enExample)
PE (1) PE20040081A1 (enExample)
PL (1) PL212322B1 (enExample)
PT (1) PT1492771E (enExample)
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SI (1) SI1492771T1 (enExample)
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