KR100668400B1 - 테트라히드로피리도에테르 - Google Patents

테트라히드로피리도에테르 Download PDF

Info

Publication number
KR100668400B1
KR100668400B1 KR1020017003553A KR20017003553A KR100668400B1 KR 100668400 B1 KR100668400 B1 KR 100668400B1 KR 1020017003553 A KR1020017003553 A KR 1020017003553A KR 20017003553 A KR20017003553 A KR 20017003553A KR 100668400 B1 KR100668400 B1 KR 100668400B1
Authority
KR
South Korea
Prior art keywords
hydroxy
dimethyl
formula
phenyl
naphthyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020017003553A
Other languages
English (en)
Korean (ko)
Other versions
KR20010075223A (ko
Inventor
포스티우스스테판
시몬볼프강-알렉산더
그룬틀러게르하르트
하나우어귀도
허버라인하르트
크로메르볼프강
스투름에른스트
센-빌핑거요르그
Original Assignee
알타나 파마 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알타나 파마 아게 filed Critical 알타나 파마 아게
Publication of KR20010075223A publication Critical patent/KR20010075223A/ko
Application granted granted Critical
Publication of KR100668400B1 publication Critical patent/KR100668400B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020017003553A 1998-09-23 1999-09-17 테트라히드로피리도에테르 Expired - Fee Related KR100668400B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
EP98117988.0 1998-09-23
DE19843504.5 1998-09-23

Publications (2)

Publication Number Publication Date
KR20010075223A KR20010075223A (ko) 2001-08-09
KR100668400B1 true KR100668400B1 (ko) 2007-01-17

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017003553A Expired - Fee Related KR100668400B1 (ko) 1998-09-23 1999-09-17 테트라히드로피리도에테르

Country Status (31)

Country Link
US (4) US6436953B1 (https=)
EP (1) EP1115725B1 (https=)
JP (1) JP4145492B2 (https=)
KR (1) KR100668400B1 (https=)
CN (2) CN1155598C (https=)
AT (1) ATE231862T1 (https=)
AU (1) AU763463B2 (https=)
BG (1) BG65195B1 (https=)
BR (1) BR9914044A (https=)
CA (1) CA2344251A1 (https=)
CZ (1) CZ292335B6 (https=)
DE (1) DE69905178T2 (https=)
DK (1) DK1115725T3 (https=)
EA (1) EA005377B1 (https=)
EE (1) EE04677B1 (https=)
ES (1) ES2191464T3 (https=)
GE (1) GEP20032926B (https=)
HK (1) HK1038360B (https=)
HR (1) HRP20010224A2 (https=)
HU (1) HUP0102990A3 (https=)
ID (1) ID28896A (https=)
IL (2) IL142063A0 (https=)
NO (1) NO317304B1 (https=)
NZ (1) NZ510610A (https=)
PL (1) PL193616B1 (https=)
PT (1) PT1115725E (https=)
RS (1) RS50145B (https=)
SI (1) SI1115725T1 (https=)
SK (1) SK285165B6 (https=)
TR (1) TR200100805T2 (https=)
WO (1) WO2000017200A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436953B1 (en) * 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
WO2000063211A1 (en) * 1999-04-17 2000-10-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Haloalkoxy imidazonaphthyridines
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
CA2404477A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Tricyclic imidazopyridines
SK286850B6 (sk) * 2000-03-29 2009-06-05 Altana Pharma Ag Prekurzory imidazopyridínových derivátov, farmaceutický prostriedok s ich obsahom a ich použitie
EA008151B1 (ru) * 2000-10-25 2007-04-27 Алтана Фарма Аг Полизамещенные имидазопиридины в качестве ингибиторов желудочной секреции
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MXPA03007888A (es) * 2001-03-08 2003-12-04 Astrazeneca Ab Compuestos para tratamiento y prevencion de ulcera gastrica inducida por medicamentos.
HUP0400379A3 (en) 2001-08-02 2007-10-29 Altana Pharma Ag Tricyclic epoxides and their use for the preparation of pharmaceutically active agents
PL368586A1 (en) * 2001-08-03 2005-04-04 Altana Pharma Ag Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders
US20040235882A1 (en) * 2001-08-03 2004-11-25 Jorg Senn-Bilfinger Amino-substituted imidazopyridines for the treatment of gastrointestial diseases
US7314935B2 (en) 2002-02-15 2008-01-01 Altana Pharma Ag Tricyclic n-acyl compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RS95304A (sr) * 2002-05-07 2006-12-15 Altana Pharma Ag. Nova kombinacija za tretman oboljenja disajnih puteva
AU2003288071A1 (en) 2002-11-19 2004-06-15 Altana Pharma Ag 8-substituted imidazopyridines
US7879833B2 (en) 2002-12-12 2011-02-01 Nycomed Gmbh Combination medicament
HRP20050632A2 (hr) * 2002-12-20 2006-04-30 Altana Pharma Ag Silil eteri
MXPA05008490A (es) * 2003-02-17 2005-10-18 Altana Pharma Ag Combinaciones que contienen imidazopiridinas y su uso en el tratamiento de enfermedades gastrointestinales inflamatorias.
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
KR20060118421A (ko) * 2003-08-29 2006-11-23 다이노젠 파마세우티컬스, 인코포레이티드 위장 운동 장애의 치료에 유용한 조성물
PT1670482E (pt) 2003-09-16 2014-03-12 Takeda Gmbh Utilização de ciclesonida para o tratamento de doenças respiratórias
KR20060099524A (ko) * 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-ａ]피리딘유도체
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
CA2579127C (en) 2004-09-03 2011-08-02 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
ATE518858T1 (de) 2004-09-03 2011-08-15 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und herstellungsverfahren dafür
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
KR101605063B1 (ko) * 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
JP6001168B2 (ja) * 2012-06-15 2016-10-05 バイオ‐ファーム ソリューションズ カンパニー リミテッドＢｉｏ‐Ｐｈａｒｍ Ｓｏｌｕｔｉｏｎｓ Ｃｏ．， Ｌｔｄ． フェニルアルキルスルファメート化合物及びこれを含む筋弛緩剤組成物
EP3054949A1 (en) 2013-10-08 2016-08-17 Katairo GmbH Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
WO1989000570A1 (fr) * 1987-07-16 1989-01-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Nouveaux diazoles
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
EP0773945A1 (de) * 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Acylimidazopyridine
EP0971922B1 (en) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyrido compounds
EA002402B1 (ru) * 1997-03-24 2002-04-25 Бык Гульден Ломберг Хемише Фабрик Гмбх Тетрагидропиридо-соединения
US6436953B1 (en) 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers

Also Published As

Publication number Publication date
US20020169320A1 (en) 2002-11-14
SK3992001A3 (en) 2001-12-03
PL193616B1 (pl) 2007-02-28
JP4145492B2 (ja) 2008-09-03
ES2191464T3 (es) 2003-09-01
KR20010075223A (ko) 2001-08-09
JP2002526499A (ja) 2002-08-20
HK1038360B (en) 2003-05-16
DE69905178D1 (de) 2003-03-06
PL346617A1 (en) 2002-02-25
US6696460B2 (en) 2004-02-24
YU21401A (sh) 2004-03-12
ID28896A (id) 2001-07-12
NO317304B1 (no) 2004-10-04
RS50145B (sr) 2009-03-25
AU6192099A (en) 2000-04-10
EA005377B1 (ru) 2005-02-24
CN1155598C (zh) 2004-06-30
HRP20010224A2 (en) 2002-04-30
CN100506821C (zh) 2009-07-01
ATE231862T1 (de) 2003-02-15
GEP20032926B (en) 2003-03-25
BG105270A (en) 2001-11-30
CZ292335B6 (cs) 2003-09-17
US20040162310A1 (en) 2004-08-19
CN1319101A (zh) 2001-10-24
EP1115725B1 (en) 2003-01-29
DE69905178T2 (de) 2003-07-17
EP1115725A1 (en) 2001-07-18
IL142063A0 (en) 2002-03-10
NO20011243D0 (no) 2001-03-12
EE04677B1 (et) 2006-08-15
US7393860B1 (en) 2008-07-01
EE200100172A (et) 2002-06-17
SK285165B6 (sk) 2006-07-07
NO20011243L (no) 2001-03-12
CA2344251A1 (en) 2000-03-30
NZ510610A (en) 2003-07-25
IL142063A (en) 2007-10-31
BR9914044A (pt) 2001-12-04
BG65195B1 (bg) 2007-06-29
HUP0102990A2 (hu) 2002-01-28
SI1115725T1 (en) 2003-06-30
EA200100315A1 (ru) 2001-10-22
PT1115725E (pt) 2003-06-30
AU763463B2 (en) 2003-07-24
WO2000017200A1 (en) 2000-03-30
HUP0102990A3 (en) 2002-09-30
US6436953B1 (en) 2002-08-20
TR200100805T2 (tr) 2001-08-21
CN1560055A (zh) 2005-01-05
HK1038360A1 (en) 2002-03-15
CZ20011082A3 (cs) 2001-09-12
US7105676B2 (en) 2006-09-12
DK1115725T3 (da) 2003-06-23

Similar Documents

Publication Publication Date Title
KR100668400B1 (ko) 테트라히드로피리도에테르
US5665730A (en) Pharmaceutically useful imidazopyridines
RU2139288C1 (ru) Алкоксиалкилкарбаматы имидазо[1,2-a]пиридинов и лекарственное средство на их основе
KR100823762B1 (ko) 알킬화된 이미다조피리딘 유도체
EP1127059B1 (en) Imidazonaphthyridines
US6197783B1 (en) Tetrahydropyrido compounds
KR100823761B1 (ko) 트리시클릭 이미다조피리딘
AU700730B2 (en) Imidazopyridine-azolidinones
KR20020082494A (ko) 위장 질환 치료용피라노[2,3-씨]이미다조[1,2-에이]피리딘 유도체
MXPA01003047A (en) Tetrahydropyridoethers
ZA200102107B (en) Tetrahydropyridoethers.

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PN2301 Change of applicant

St.27 status event code: A-3-3-R10-R13-asn-PN2301

St.27 status event code: A-3-3-R10-R11-asn-PN2301

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20100109

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20100109

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000