HK1038360B - Tetrahydropyridoethers - Google Patents

Tetrahydropyridoethers Download PDF

Info

Publication number
HK1038360B
HK1038360B HK02100042.6A HK02100042A HK1038360B HK 1038360 B HK1038360 B HK 1038360B HK 02100042 A HK02100042 A HK 02100042A HK 1038360 B HK1038360 B HK 1038360B
Authority
HK
Hong Kong
Prior art keywords
hydroxy
dimethyl
phenyl
naphthyridine
methoxyethoxy
Prior art date
Application number
HK02100042.6A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1038360A1 (en
Inventor
Postius Stefan
Simon Wolfgang-Alexander
Grundler Gerhard
Hanauer Guido
Huber Reinhard
Kromer Wolfgang
Sturm Ernst
Senn-Bilfinger Jorg
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of HK1038360A1 publication Critical patent/HK1038360A1/en
Publication of HK1038360B publication Critical patent/HK1038360B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK02100042.6A 1998-09-23 1999-09-17 Tetrahydropyridoethers HK1038360B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
DE19843504.5 1998-09-23
EP98117988.0 1998-09-23
PCT/EP1999/006899 WO2000017200A1 (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Publications (2)

Publication Number Publication Date
HK1038360A1 HK1038360A1 (en) 2002-03-15
HK1038360B true HK1038360B (en) 2003-05-16

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100042.6A HK1038360B (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Country Status (31)

Country Link
US (4) US6436953B1 (https=)
EP (1) EP1115725B1 (https=)
JP (1) JP4145492B2 (https=)
KR (1) KR100668400B1 (https=)
CN (2) CN100506821C (https=)
AT (1) ATE231862T1 (https=)
AU (1) AU763463B2 (https=)
BG (1) BG65195B1 (https=)
BR (1) BR9914044A (https=)
CA (1) CA2344251A1 (https=)
CZ (1) CZ292335B6 (https=)
DE (1) DE69905178T2 (https=)
DK (1) DK1115725T3 (https=)
EA (1) EA005377B1 (https=)
EE (1) EE04677B1 (https=)
ES (1) ES2191464T3 (https=)
GE (1) GEP20032926B (https=)
HK (1) HK1038360B (https=)
HR (1) HRP20010224A2 (https=)
HU (1) HUP0102990A3 (https=)
ID (1) ID28896A (https=)
IL (2) IL142063A0 (https=)
NO (1) NO317304B1 (https=)
NZ (1) NZ510610A (https=)
PL (1) PL193616B1 (https=)
PT (1) PT1115725E (https=)
RS (1) RS50145B (https=)
SI (1) SI1115725T1 (https=)
SK (1) SK285165B6 (https=)
TR (1) TR200100805T2 (https=)
WO (1) WO2000017200A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE04677B1 (et) 1998-09-23 2006-08-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahdropridoeetrid, nende kasutamine ja ravim
JP2002542248A (ja) * 1999-04-17 2002-12-10 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ハロアルコキシイミダゾナフチリジン
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
MXPA02009549A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Imidazopiridinas triciclicas.
KR100860627B1 (ko) * 2000-03-29 2008-09-29 니코메드 게엠베하 이미다조피리딘 유도체의 프로드러그
PL360412A1 (en) * 2000-10-25 2004-09-06 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
EP1370261A2 (en) * 2001-03-08 2003-12-17 AstraZeneca AB New use
US6927292B2 (en) 2001-08-02 2005-08-09 Altana Pharma Ag Tricyclic epoxides
NZ531433A (en) * 2001-08-03 2005-09-30 Altana Pharma Ag Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders
WO2003014120A1 (en) * 2001-08-03 2003-02-20 Altana Pharma Ag Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
HRP20040834A2 (en) 2002-02-15 2005-06-30 Altana Pharma Ag Tricyclic n-acyl compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1506016A2 (en) * 2002-05-07 2005-02-16 ALTANA Pharma AG New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
CA2506027A1 (en) 2002-11-19 2004-06-03 Altana Pharma Ag 8-substituted imidazopyridines
ES2312844T3 (es) 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
BR0316752A (pt) * 2002-12-20 2005-10-25 Altana Pharma Ag Silil éteres
BRPI0407541A (pt) * 2003-02-17 2006-02-14 Altana Pharma Ag combinações e uso de compostos farmaceuticamente ativos selecionados
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
JP2006528231A (ja) * 2003-05-27 2006-12-14 アルタナ　ファルマ　アクチエンゲゼルシャフト プロトンポンプ阻害剤と胃腸運動性を変更する化合物との医薬品組合せ物
BRPI0414046A (pt) * 2003-08-29 2006-10-24 Dynogen Pharmaceuticals Inc método de tratamento de um distúrbio de motilidade gastrintestinal, de tratamento de "gerd", de "gerd" noturno, composição farmacêutica, kit que compreende um composto e método para aumentar a motilidade esofágica em um paciente
AU2004271744B2 (en) 2003-09-16 2010-07-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
EP1682133A1 (en) * 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
EP1697358A1 (en) 2003-12-19 2006-09-06 Altana Pharma AG Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
MX2007002214A (es) 2004-09-03 2007-05-07 Yuhan Corp Derivados de pirrolo[3,2-c]piridina y procesos para su preparacion.
KR100958828B1 (ko) 2004-09-03 2010-05-24 주식회사유한양행 피롤로[3,2-ｂ]피리딘 유도체 및 그의 제조방법
DK1784404T3 (da) 2004-09-03 2012-02-13 Yuhan Corp Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
WO2013187727A1 (en) * 2012-06-15 2013-12-19 Bio-Pharm Solutions Co., Ltd. Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same
EP3054949A1 (en) 2013-10-08 2016-08-17 Katairo GmbH Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
KR890701585A (ko) * 1987-07-16 1989-12-21 헤르베르크 슈키·울리히 볼프 새로운 디아졸
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
NZ290819A (en) * 1994-07-28 1998-06-26 Byk Gulden Lomberg Chem Fab Acyl 8-benzyloxy- or 8-benzylaminoimidazopyridines
AU740578B2 (en) * 1997-03-24 2001-11-08 Altana Pharma Ag Tetrahydropyrido compounds
EP0971922B1 (en) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyrido compounds
EE04677B1 (et) 1998-09-23 2006-08-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahdropridoeetrid, nende kasutamine ja ravim

Also Published As

Publication number Publication date
AU763463B2 (en) 2003-07-24
SK3992001A3 (en) 2001-12-03
HUP0102990A3 (en) 2002-09-30
SK285165B6 (sk) 2006-07-07
NO317304B1 (no) 2004-10-04
ES2191464T3 (es) 2003-09-01
EE200100172A (et) 2002-06-17
RS50145B (sr) 2009-03-25
NZ510610A (en) 2003-07-25
NO20011243D0 (no) 2001-03-12
SI1115725T1 (en) 2003-06-30
ATE231862T1 (de) 2003-02-15
HK1038360A1 (en) 2002-03-15
US20040162310A1 (en) 2004-08-19
CN1560055A (zh) 2005-01-05
CN100506821C (zh) 2009-07-01
US7393860B1 (en) 2008-07-01
GEP20032926B (en) 2003-03-25
KR20010075223A (ko) 2001-08-09
BG105270A (en) 2001-11-30
US7105676B2 (en) 2006-09-12
CZ292335B6 (cs) 2003-09-17
HRP20010224A2 (en) 2002-04-30
AU6192099A (en) 2000-04-10
CZ20011082A3 (cs) 2001-09-12
IL142063A0 (en) 2002-03-10
WO2000017200A1 (en) 2000-03-30
DE69905178D1 (de) 2003-03-06
DK1115725T3 (da) 2003-06-23
TR200100805T2 (tr) 2001-08-21
NO20011243L (no) 2001-03-12
PL346617A1 (en) 2002-02-25
IL142063A (en) 2007-10-31
CN1155598C (zh) 2004-06-30
EP1115725B1 (en) 2003-01-29
CA2344251A1 (en) 2000-03-30
EA005377B1 (ru) 2005-02-24
KR100668400B1 (ko) 2007-01-17
BG65195B1 (bg) 2007-06-29
CN1319101A (zh) 2001-10-24
ID28896A (id) 2001-07-12
EE04677B1 (et) 2006-08-15
YU21401A (sh) 2004-03-12
JP2002526499A (ja) 2002-08-20
JP4145492B2 (ja) 2008-09-03
US6696460B2 (en) 2004-02-24
EP1115725A1 (en) 2001-07-18
EA200100315A1 (ru) 2001-10-22
US6436953B1 (en) 2002-08-20
BR9914044A (pt) 2001-12-04
PL193616B1 (pl) 2007-02-28
US20020169320A1 (en) 2002-11-14
HUP0102990A2 (hu) 2002-01-28
DE69905178T2 (de) 2003-07-17
PT1115725E (pt) 2003-06-30

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090917