HUP0102990A3 - Tetrahydroimidazo-naphtyridine derivatives and pharmaceutical compositions thereof - Google Patents

Tetrahydroimidazo-naphtyridine derivatives and pharmaceutical compositions thereof

Info

Publication number
HUP0102990A3
HUP0102990A3 HU0102990A HUP0102990A HUP0102990A3 HU P0102990 A3 HUP0102990 A3 HU P0102990A3 HU 0102990 A HU0102990 A HU 0102990A HU P0102990 A HUP0102990 A HU P0102990A HU P0102990 A3 HUP0102990 A3 HU P0102990A3
Authority
HU
Hungary
Prior art keywords
tetrahydroimidazo
pharmaceutical compositions
naphtyridine
derivatives
naphtyridine derivatives
Prior art date
Application number
HU0102990A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of HUP0102990A2 publication Critical patent/HUP0102990A2/hu
Publication of HUP0102990A3 publication Critical patent/HUP0102990A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HU0102990A 1998-09-23 1999-09-17 Tetrahydroimidazo-naphtyridine derivatives and pharmaceutical compositions thereof HUP0102990A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
PCT/EP1999/006899 WO2000017200A1 (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Publications (2)

Publication Number Publication Date
HUP0102990A2 HUP0102990A2 (hu) 2002-01-28
HUP0102990A3 true HUP0102990A3 (en) 2002-09-30

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102990A HUP0102990A3 (en) 1998-09-23 1999-09-17 Tetrahydroimidazo-naphtyridine derivatives and pharmaceutical compositions thereof

Country Status (31)

Country Link
US (4) US6436953B1 (https=)
EP (1) EP1115725B1 (https=)
JP (1) JP4145492B2 (https=)
KR (1) KR100668400B1 (https=)
CN (2) CN1155598C (https=)
AT (1) ATE231862T1 (https=)
AU (1) AU763463B2 (https=)
BG (1) BG65195B1 (https=)
BR (1) BR9914044A (https=)
CA (1) CA2344251A1 (https=)
CZ (1) CZ292335B6 (https=)
DE (1) DE69905178T2 (https=)
DK (1) DK1115725T3 (https=)
EA (1) EA005377B1 (https=)
EE (1) EE04677B1 (https=)
ES (1) ES2191464T3 (https=)
GE (1) GEP20032926B (https=)
HK (1) HK1038360B (https=)
HR (1) HRP20010224A2 (https=)
HU (1) HUP0102990A3 (https=)
ID (1) ID28896A (https=)
IL (2) IL142063A0 (https=)
NO (1) NO317304B1 (https=)
NZ (1) NZ510610A (https=)
PL (1) PL193616B1 (https=)
PT (1) PT1115725E (https=)
RS (1) RS50145B (https=)
SI (1) SI1115725T1 (https=)
SK (1) SK285165B6 (https=)
TR (1) TR200100805T2 (https=)
WO (1) WO2000017200A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436953B1 (en) * 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
WO2000063211A1 (en) * 1999-04-17 2000-10-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Haloalkoxy imidazonaphthyridines
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
CA2404477A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Tricyclic imidazopyridines
SK286850B6 (sk) * 2000-03-29 2009-06-05 Altana Pharma Ag Prekurzory imidazopyridínových derivátov, farmaceutický prostriedok s ich obsahom a ich použitie
EA008151B1 (ru) * 2000-10-25 2007-04-27 Алтана Фарма Аг Полизамещенные имидазопиридины в качестве ингибиторов желудочной секреции
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MXPA03007888A (es) * 2001-03-08 2003-12-04 Astrazeneca Ab Compuestos para tratamiento y prevencion de ulcera gastrica inducida por medicamentos.
HUP0400379A3 (en) 2001-08-02 2007-10-29 Altana Pharma Ag Tricyclic epoxides and their use for the preparation of pharmaceutically active agents
PL368586A1 (en) * 2001-08-03 2005-04-04 Altana Pharma Ag Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders
US20040235882A1 (en) * 2001-08-03 2004-11-25 Jorg Senn-Bilfinger Amino-substituted imidazopyridines for the treatment of gastrointestial diseases
US7314935B2 (en) 2002-02-15 2008-01-01 Altana Pharma Ag Tricyclic n-acyl compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RS95304A (sr) * 2002-05-07 2006-12-15 Altana Pharma Ag. Nova kombinacija za tretman oboljenja disajnih puteva
AU2003288071A1 (en) 2002-11-19 2004-06-15 Altana Pharma Ag 8-substituted imidazopyridines
US7879833B2 (en) 2002-12-12 2011-02-01 Nycomed Gmbh Combination medicament
HRP20050632A2 (hr) * 2002-12-20 2006-04-30 Altana Pharma Ag Silil eteri
MXPA05008490A (es) * 2003-02-17 2005-10-18 Altana Pharma Ag Combinaciones que contienen imidazopiridinas y su uso en el tratamiento de enfermedades gastrointestinales inflamatorias.
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
KR20060118421A (ko) * 2003-08-29 2006-11-23 다이노젠 파마세우티컬스, 인코포레이티드 위장 운동 장애의 치료에 유용한 조성물
PT1670482E (pt) 2003-09-16 2014-03-12 Takeda Gmbh Utilização de ciclesonida para o tratamento de doenças respiratórias
KR20060099524A (ko) * 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-a]피리딘유도체
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
CA2579127C (en) 2004-09-03 2011-08-02 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-c]피리딘 유도체 및 그의 제조방법
ATE518858T1 (de) 2004-09-03 2011-08-15 Yuhan Corp Pyrroloä3,2-cüpyridinderivate und herstellungsverfahren dafür
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
KR101605063B1 (ko) * 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
JP6001168B2 (ja) * 2012-06-15 2016-10-05 バイオ‐ファーム ソリューションズ カンパニー リミテッドBio‐Pharm Solutions Co., Ltd. フェニルアルキルスルファメート化合物及びこれを含む筋弛緩剤組成物
EP3054949A1 (en) 2013-10-08 2016-08-17 Katairo GmbH Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
WO1989000570A1 (fr) * 1987-07-16 1989-01-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Nouveaux diazoles
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
EP0773945A1 (de) * 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Acylimidazopyridine
EP0971922B1 (en) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyrido compounds
EA002402B1 (ru) * 1997-03-24 2002-04-25 Бык Гульден Ломберг Хемише Фабрик Гмбх Тетрагидропиридо-соединения
US6436953B1 (en) 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers

Also Published As

Publication number Publication date
US20020169320A1 (en) 2002-11-14
SK3992001A3 (en) 2001-12-03
PL193616B1 (pl) 2007-02-28
JP4145492B2 (ja) 2008-09-03
ES2191464T3 (es) 2003-09-01
KR20010075223A (ko) 2001-08-09
JP2002526499A (ja) 2002-08-20
HK1038360B (en) 2003-05-16
DE69905178D1 (de) 2003-03-06
PL346617A1 (en) 2002-02-25
US6696460B2 (en) 2004-02-24
YU21401A (sh) 2004-03-12
ID28896A (id) 2001-07-12
NO317304B1 (no) 2004-10-04
RS50145B (sr) 2009-03-25
AU6192099A (en) 2000-04-10
EA005377B1 (ru) 2005-02-24
CN1155598C (zh) 2004-06-30
HRP20010224A2 (en) 2002-04-30
KR100668400B1 (ko) 2007-01-17
CN100506821C (zh) 2009-07-01
ATE231862T1 (de) 2003-02-15
GEP20032926B (en) 2003-03-25
BG105270A (en) 2001-11-30
CZ292335B6 (cs) 2003-09-17
US20040162310A1 (en) 2004-08-19
CN1319101A (zh) 2001-10-24
EP1115725B1 (en) 2003-01-29
DE69905178T2 (de) 2003-07-17
EP1115725A1 (en) 2001-07-18
IL142063A0 (en) 2002-03-10
NO20011243D0 (no) 2001-03-12
EE04677B1 (et) 2006-08-15
US7393860B1 (en) 2008-07-01
EE200100172A (et) 2002-06-17
SK285165B6 (sk) 2006-07-07
NO20011243L (no) 2001-03-12
CA2344251A1 (en) 2000-03-30
NZ510610A (en) 2003-07-25
IL142063A (en) 2007-10-31
BR9914044A (pt) 2001-12-04
BG65195B1 (bg) 2007-06-29
HUP0102990A2 (hu) 2002-01-28
SI1115725T1 (en) 2003-06-30
EA200100315A1 (ru) 2001-10-22
PT1115725E (pt) 2003-06-30
AU763463B2 (en) 2003-07-24
WO2000017200A1 (en) 2000-03-30
US6436953B1 (en) 2002-08-20
TR200100805T2 (tr) 2001-08-21
CN1560055A (zh) 2005-01-05
HK1038360A1 (en) 2002-03-15
CZ20011082A3 (cs) 2001-09-12
US7105676B2 (en) 2006-09-12
DK1115725T3 (da) 2003-06-23

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees